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Animal models of bingeing have typically used stress to induce bingeing. A recent model, limited-access to high-fat diet (HFD), has shown that caloric restriction and stress were not required to induce bingeing in rats. This study replicated this model in mice, explored the fat content within the model, and investigated locomotor activation associated with binge-eating. Adult mice were maintained on a restricted feeding (RF) schedule of 2 h/d of access to chow or ad lib access to chow, and then provided limited access to 45% HFD or 84% HFD for 30 min 3 d/ week for 6 total snack sessions. Circadian activity was monitored for RF animals offered 84% HFD, and after 6 snack sessions were complete, allowed continuous access to the 45% HFD or the 84% HFD for two weeks to explore rebound feeding. Bingeing, defined by increasing intakes across days, was reported for mice offered 45% HFD regardless of deprivation state (RF or ad lib), while mice offered 84% HFD only exhibited bingeing when they were restricted. Comparison of male and female mice maintained RF, offered 45% HFD snack, showed that females had higher intake (kcals/g-bw) while ad lib fed mice exhibited no sex differences. Circadian recordings for female RF mice offered 84% HFD showed shifts in activity from the first hour of dark cycle to the hour preceding the snack and supported that offering the HFD produced alterations in food-associated arousal. During rebound, female RF mice given 84% HFD showed the highest intakes in week 1, and then exhibited a marked decline in week 2. The week 1 intake for RF animals were to regain lost body weight and that homeostatic-like intake in week 2 allowed normal body weight maintenance. Results of this investigation support human data that females are more susceptible to binge-type eating disorder, shows that limited access to palatable foods for females under caloric restriction induces changes in circadian activity, and reveals that using mice in this model requires more investigation to optimize binge-behavior. Diet comparisons also suggest that homeostatic and reward mechanisms may have an additive effect on bingeing.

This thesis determines and examines the obstacles to Saudi women's right to work in terms of religious and cultural barriers and limited access to higher education through an analysis of Sharia sources, Saudi domestic law and international human rights treaties pertaining to Saudi women's right to work in the Kingdom of Saudi Arabia. It also delineates the provisions for women's right to work in Sharia and Saudi domestic law in the public and private sectors. The thesis also examines the reservations that the Kingdom of Saudi Arabia has entered into, and some of the international human rights treaties it has ratified, with a particular focus on the application of the Convention on the Elimination of All Forms of Discrimination against Women (CEDAW). It also examines Saudi Arabia's obligations under International Labour Organization (ILO) Conventions. In the context of Saudi domestic law, it identifies obstacles that underlie Saudi Arabia's decision not to ratify the International Covenant on Economic, Social and Cultural Rights (ICESCR); it examines the arguments for the Kingdom of Saudi Arabia signing up to the ICESCR; and it examines Saudi Arabia's obligations to respect, protect and fulfil women's right to work under CEDAW. The protection of women's right to work under customary international law, by its sources will be explored. This section will look through customary international law elements; whether or not women's right to work is protected. Finally, the thesis provides recommendations for action which can be taken by the Kingdom of Saudi Arabia to provide Saudi women with equal rights to work. It also makes recommendations concerning ratified and pending international human rights treaties which have the capacity to protect Saudi women's right to work.

The environment is taking a larger part of the debate resulting in the creation of UN declarations, domestic and regional laws, public pressure on companies and politicians to take responsibility, and a greater awareness on our increasingly exploited planet. However, the people who are affected the most, poor and often indigenous people, find themselves in an increasingly dangerous position when they try to defend the planet. Previous research lack understanding on which features that facilitates deadly violence against environmentalists. In contemporary time, three environmentalists per week die when they try to defend the planet from environmental harm, making it more than twice as dangerous as being a journalist. This thesis tries to answer - what explains deadly violence against environmentalists in developing countries by using the method of structured focused comparison (SFC). Honduras is the deadliest country per capita for environmentalists and they will be compared with El Salvador, which does not experience a high degree of deadly violence against environmentalists. The attributes tested are chosen in accordance with the analytical framework of Limited Access Orders (LAO). LAOs are controlled by elites who create rents to maintain their power, hence decreasing elites power by enforcing open access orders (OAO) in LAO can result in increased violence. Honduras and El Salvador’s differences suggest that environmentalists have been subjected to enhanced dangerous circumstances in Honduras than environmentalists in El Salvador and historical conditions have resulted in the protection of the environment in El Salvador by the wider social movement. Earlier research in Honduras has pointed at the importance to decrease corruption in order to decrease violence against environmentalists. However, the theory of LAO suggests that attempts to abolish corruption, increase access, institute democracy or increase rule of law surge violence. In order to limit deadly violence against environmentalists, this study suggests that Honduras focus should be at: prevent expropriation, limit international corporations access on natural resources, attain consent from the local communities before starting projects, require corporations and organizations to publish public environmental assessment reports before projects starts that can degrade the environment and increase focus on the manufacturing sector instead of extraction of natural resources.

Background In remote areas of the Peruvian Amazon there is a high burden of communicable diseases, limited access to health care and a low distribution of registered nurses. Registered nurses are working with indigenous patients in the area, where traditional medicine and practice is common. In order to strengthen the relation between western and traditional practices, intercultural health has been implemented within the public health care. Aim The aim was to describe registered nurses’ experiences of working with indigenous patients in remote health care settings in Loreto region, Peruvian Amazon. Method A qualitative field study with semi-structured interviews was conducted at four health clinics in Maynas and Mariscal Ramón Castilla province. A qualitative content analysis was used when analyzing the data. Findings Three categories were identified in the analysis; Working environment in a remote area, Providing health care for indigenous patients and Including intercultural health in nursing practice. The participants’ daily work with few colleagues and high demand in remote clinics was described. Experiences of working with intercultural health, as well as opportunities and challenges of working with indigenous patients was found. Conclusion The registered nurses work in an area with a high workload, limited resources and geographic isolation. Intercultural implementations were shown to improve intercultural relations, autonomy and health. Challenges between registered nurses and indigenous patients related to communication and different cultures were described. In order to improve the situation and reach the UN Sustainable Development Goals, infrastructural and socio-economic improvements, more resources and health professionals are necessary.

The decline of the world’s fisheries, and the inability of traditional management frameworks to maintain them, has led managers to adopt new, alternative management frameworks. Alternative management frameworks include marine protected areas (MPA) and dedicated access privileges (DAP). The use of such frameworks has often been shown to be quite unpopular, especially with commercial fishers. In this thesis, commercial fishers’ preference for alternative management frameworks is examined in the context of the unique multispecies fisheries of the Florida Keys. By surveying commercial fishers, it was found that the size of operation plays no role in affecting fisher perception of dedicated access privileges. Furthermore, fishers who are organized are less likely to support dedicated access privilege frameworks. Finally, the fishing industry does not support the implementation of dedicated access privileges in the Florida Keys. These findings can provide inputs for managers in developing effective management plans in the region.

Cette thèse traite de l’établissement d’une plateforme logicielle nommée DaWeS permettant le déploiement et la gestion en ligne d’entrepôts de données alimentés par des données provenant de services web et personnalisés à destination des petites et moyennes entreprises. Ce travail s’articule autour du développement et de l’expérimentation de DaWeS. L’idée principale implémentée dans DaWeS est l’utilisation d’une approche virtuelle d’intégration de données (la médiation) en tant queprocessus ETL (extraction, transformation et chargement des données) pour les entrepôts de données gérés par DaWeS. A cette fin, un algorithme classique de réécriture de requêtes (l’algorithme inverse-rules) a été adapté et testé. Une étude théorique sur la sémantique des requêtes conjonctives et datalog exprimées avec des relations munies de limitations d’accès (correspondant aux services web) a été menée. Cette dernière permet l’obtention de bornes supérieures sur les nombres d’appels aux services web requis dans l’évaluation de telles requêtes. Des expérimentations ont été menées sur des services web réels dans trois domaines : le marketing en ligne, la gestion de projets et les services d’aide aux utilisateurs. Une première série de tests aléatoires a été effectuée pour tester le passage à l’échelle. / The role of data warehouse for business analytics cannot be undermined for any enterprise, irrespective of its size. But the growing dependence on web services has resulted in a situation where the enterprise data is managed by multiple autonomous and heterogeneous service providers. We present our approach and its associated prototype DaWeS [Samuel, 2014; Samuel and Rey, 2014; Samuel et al., 2014], a DAta warehouse fed with data coming from WEb Services to extract, transform and store enterprise data from web services and to build performance indicators from them (stored enterprise data) hiding from the end users the heterogeneity of the numerous underlying web services. Its ETL process is grounded on a mediation approach usually used in data integration. This enables DaWeS (i) to be fully configurable in a declarative manner only (XML, XSLT, SQL, datalog) and (ii) to make part of the warehouse schema dynamic so it can be easily updated. (i) and (ii) allow DaWeS managers to shift from development to administration when they want to connect to new web services or to update the APIs (Application programming interfaces) of already connected ones. The aim is to make DaWeS scalable and adaptable to smoothly face the ever-changing and growing web services offer. We point out the fact that this also enables DaWeS to be used with the vast majority of actual web service interfaces defined with basic technologies only (HTTP, REST, XML and JSON) and not with more advanced standards (WSDL, WADL, hRESTS or SAWSDL) since these more advanced standards are not widely used yet to describe real web services. In terms of applications, the aim is to allow a DaWeS administrator to provide to small and medium companies a service to store and query their business data coming from their usage of third-party services, without having to manage their own warehouse. In particular, DaWeS enables the easy design (as SQL Queries) of personalized performance indicators. We present in detail this mediation approach for ETL and the architecture of DaWeS. Besides its industrial purpose, working on building DaWeS brought forth further scientific challenges like the need for optimizing the number of web service API operation calls or handling incomplete information. We propose a bound on the number of calls to web services. This bound is a tool to compare future optimization techniques. We also present a heuristics to handle incomplete information.

En el Perú existe un gran déficit educacional y generalmente esto se refleja con mayor énfasis en los pueblos, localidades, caseríos y zonas alejadas donde el acceso es limitado, carecen de servicios básicos y falta de comunicación. La provincia de Purús, ubicada en la región de Ucayali, es un claro ejemplo de este déficit por el grado de aislamiento que presenta. El inicio de clases en las distintos instituciones educativos a lo largo de esta región se ve afectado por diferentes motivos como es el retraso con el abastecimiento de materiales educativos, lo que ocasiona una frecuente inasistencia del docente y alumno. En la presente tesis se plantea realizar el diseño de un enlace satelital-terrestre que permita, tanto al alumno como al docente de las instituciones educativas en Purús, acceder a materiales educativos actualizados y de calidad. Este servicio será ofrecido vía intranet, cuyo material será dado por el Ministerio de Educación, y vía internet para que el alumno pueda hacer uso de los todos beneficios que ofrece este. In Peru there is a great educational deficit and generally this is reflected more strongly in the villages, towns, villages and remote areas where access is limited, lack basic services and lack of communication. Purus province, located in Ucayali region, is a clear example of this deficit by the degree of isolation that presents. The beginning of classes in the various educational institutions throughout this region is affected by different reasons such as delay in the supply of educational materials, causing frequent absences of teachers and students. In this thesis it is proposed to make a design of a satellite-terrestrial link enabling both students and teachers of the educational institutions in Purus, access to updated educational materials and quality. This service will be offered via intranet, which material will be given by the Ministry of Education and via internet so that students can make use of all benefits that offers this.

The subject of this final thesis is research study, which deals with new, respectively modernized route between cities Pelhřimov and Humpolec. Both of these cities are located in Pelhřimov district, Vysočina region. Route is designed in three variants: motorway, limited access road and modernization of existing road to a 2+1 configuration. Thesis is a response to new concept of motorway network, which was released by Ministry of Transportation in 2020. In this concept, there is also a plan to build new ring road, which would connect main roads in Bohemia and it would ease Prague and its surroundings from traffic.

The aim of this research is to bridge the correlation of peace and foreign investments through the lens of North et al.’s (2013) Limited Access Orders (LAOs). The research seeks to engage in the discussion of LAOs by providing a perspective from analyzing Chinese investments under the context of New Silk Road policy with the case of Tasang Dam. Current discussion of LAOs does not involve how foreign investments affect institutional transition in LAOs. Therefore this research is a humble attempt to engage in the existing literature from a different perspective.         Tasang Dam is designed to be built in southern Shan State, Myanmar, an area that has encountered continuous armed conflicts. The conflicts between the local armed group SSA-S/RCSS and the Tatmadaw continue even after a ceasefire agreement was signed in 2011. Chinese investors acting under the context of New Silk Road project have tried to involve in creating stability in the area to reduce costs.         According to the LAOs logic, if the access to rents is open to armed organizations, there will be motivations for rival parties to avoid violence. In order to redistribute the resources, there should be an institutional transition. In Tasang Dam’s case, the rents created by Chinese investments are not available to SSA-S/RCSS, but with the Chinese investments as the democratization of Myanmar goes on, there are opportunities to alter the story of repeated violence.