This study used mixed methods to examine the impact of service-members‟ knowledge and acknowledgement of Posttraumatic Stress Disorder (PTSD) on relationship satisfaction of both the service-members and their spouses. Family stress theory was used to conceptualize the relationship between the occurrence of PTSD and relationship satisfaction. Forty individuals (i.e., 20 couples) completed questionnaires containing self-report measures of knowledge of PTSD, experience of PTSD symptoms, severity of PTSD symptoms, and relationship satisfaction. Participants also completed semi-structured interviews concerning PTSD symptoms, impact of PTSD symptoms on their relationship, and attitudes observed about PTSD. No significant links were found between knowledge, acknowledgement, and relationship satisfaction. Qualitative analysis of semi-structured interviews found that the couples‟ experiences of PTSD symptoms and the impact of PTSD on the couple relationships were consistent with the existing literature. Common attitudes regarding PTSD were reported by the couples, indicating a persistent negative attitude of PTSD.

Veterans of the Iraqi and Afghanistan conflicts have frequently returned with injuries such as mild traumatic brain injury (mTBI) and posttraumatic stress disorder (PTSD). More recently, concern has been raised about the large number of returning soldiers who are diagnosed with both. Literature exists on the neuropsychological factors associated with either alone, however far less research has explored the effects when combined (PTSD+mTBI). With a sample of 206 OEF/OIF veterans, the current study employed neuropsychological and psychological measures to determine whether participants with PTSD+mTBI have poorer cognitive and psychological outcomes than participants with PTSD-o, mTBI-o, or veteran controls (VC), when groups are matched on IQ, education, and age. The PTSD+mTBI and mTBI-o groups exhibited very similar neuropsychology profiles, and both PTSD+mTBI and mTBI-o performed significantly (α=.01) worse than VC on executive functioning and processing speed measures. There were no significant differences between VC and PTSD-o on any notable neuropsychology measures. In contrast, on the psychological measures, the PTSD+mTBI and PTSD-o groups were identical to each other and more distressed than either mTBI-o or VC. These findings suggest there are lasting cognitive impairments following mTBI that are unique to the condition and cannot be attributed to known impairments associated with distress.

In einer längsschnittlichen Untersuchung wurden 64 Patienten der unfallchirurgischen Abteilung einer Universitätsklinik 10 Tage und 3 Monate nach einem Verkehrsunfall untersucht. Erhoben wurden die posttraumatische Belastungssymptomatik und Gedankenkontrollstrategien. Zum ersten Untersuchungszeitpunkt (10 Tage) zeigt sich eine der Posttraumatischen Belastungsstörung (PTB) äquivalente Belastungssymptomatik bei 14,1% und nach 3 Monaten eine PTB-Prävalenz von 39,1%. Es zeigen sich Zusammenhänge zwischen einigen Gedankenkontrollstrategien und PTB-Symptomatik nach 10 Tagen und, in schwächerer Ausprägung auch nach 3 Monaten. Im Ergebnis einer explorativen Auswertung zeigt sich, daß insbesondere die Strategien «Ablenkung» und «Sorgen» eine relevante Rolle im Zusammenhang mit der PTB-Symptomatik spielen. / In a longitudinal survey 64 inpatients of an emergency clinic were examined 1 week as well as 3 months after a motor vehicle accident. Posttraumatic stress symptoms and strategies of thought control were assessed. Ten days after the accident, a posttraumatic stress symptomatology is observable in 14.1% of patients, 3 months after the accident the prevalence of posttraumatic stress disorder (PTSD) is 39.1%. Strategies of thought control are correlated with posttraumatic symptomatology 10 days after the accident and after 3 months. The result of an explorative data analysis shows an important role of the control strategies ’distraction’ and ’worry’ in correlation with posttraumatic stress symptoms. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

This study examined the influence of social support on the relationship between posttraumatic stress disorder and comorbid psychopathology, suicidal behaviour, and mental and physical health functioning in the general population. Data came from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) (N=34,653). Results showed a differential impact of posttraumatic stress disorder and social support depending on gender. For men, social support had a moderating effect, where social support had a greater influence on the prevalence of comorbid psychopathology for men with posttraumatic stress disorder compared to those without the disorder. In contrast, social support had an additive effect for women, where social support was associated with decreased psychopathology and posttraumatic stress disorder was associated with increased psychopathology. This study suggests that social support should be included in the treatment of men with posttraumatic stress disorder and encouraged among women regardless of mental disorder diagnosis.

Attention biases to trauma-related information contribute to symptom maintenance in Posttraumatic Stress Disorder (PTSD); this phenomenon has been observed through various behavioral studies, although findings from studies using a precise, direct bias task, the dot probe, have been mixed. PTSD neuroimaging studies have indicated atypical function in specific brain regions involved with attention bias; when viewing emotionally-salient cues or engaging in tasks that require attention, individuals with PTSD have demonstrated altered activity in brain regions implicated in cognitive control and attention allocation, including the medial prefrontal cortex (mPFC), dorsolateral prefrontal cortex (dlPFC) and amygdala. However, remarkably few PTSD neuroimaging studies have employed tasks that both measure attentional strategies being engaged and include emotionally-salient information. In the current study of attention biases in highly traumatized African-American adults, a version of the dot probe task that includes stimuli that are both salient (threatening facial expressions) and relevant (photographs of African-American faces) was administered to 19 participants with and without PTSD during functional magnetic resonance imaging (fMRI). I hypothesized that: 1) individuals with PTSD would show a significantly greater attention bias to threatening faces than traumatized controls; 2) PTSD symptoms would be associated with a significantly greater attentional bias toward threat expressed in African-American, but not Caucasian, faces; 3) PTSD symptoms would be significantly associated with abnormal activity in the mPFC, dlPFC, and amygdala during presentation of threatening faces. Behavioral data did not provide evidence of attentional biases associated with PTSD. However, increased activation in the dlPFC and regions of the mPFC in response to threat cues was found in individuals with PTSD, relative to traumatized controls without PTSD; this may reflect hyper-engaged cognitive control, attention, and conflict monitoring resources in these individuals. Additionally, viewing threat in same-race, both not other-race, faces was associated with increased activation in the mPFC. These findings have important theoretical and treatment implications, suggesting that PTSD, particularly in those individuals who have experienced chronic or multiple types of trauma, may be characterized less by top-down “deficits” or failures, but by imbalanced neurobiological and cognitive systems that become over-engaged in order to “control” the emotional disruption caused by trauma-related triggers.

Childhood maltreatment increases risk for Posttraumatic Stress Disorder (PTSD). Maladaptive patterns of attention to threat-related stimuli warrant examination as possible contributing risk factors. It remains unclear whether persistent threat-processing biases are differentially apparent in adults who were maltreated as children and either did, or did not, develop later PTSD. The present study examined associations among attention bias, childhood maltreatment, and PTSD in adults. We hypothesized that attentional bias toward threat significantly mediates associations between childhood maltreatment and adult PTSD symptoms. 183 adults with and without childhood maltreatment histories participated in this study, which involved completion of a range of clinical measures; attention bias was measured by the Dot Probe task. We found that attention bias toward happy faces partially mediated the relationship between childhood maltreatment and PTSD avoidance and numbing symptoms. Childhood maltreatment, happy face attention bias, and perceived racially discriminative experiences all accounted for significant variance in PTSD symptoms.

Posttraumatic Stress Disorder (PTSD) is a psychiatric condition that can develop following exposure to a traumatic event involving actual or threatened death or serious injury. Responses include intense fear, helplessness or horror. Symptoms are characterised into clusters, described as re-experiencing, avoidance, and arousal. These symptoms, which are also evident in other conditions, have been associated with dysfunctions in the central acetylcholinergic system. Benefits from administering acetylcholinesterase inhibitors (AChEI) to people suffering these symptoms have been demonstrated. Donepezil hydrochloride, a reversible inhibitor of the enzyme acetylcholinesterase, is used in the treatment of conditions with difficulties in cognitive function, but has not been used in PTSD. The aim of this thesis was to determine (1) whether there was a difference in the ACh system in people with PTSD and (2) whether administration of an AChEI would change the symtomatology. IDEX (I¹ ² ³ iododexetimide) has been useful in imaging muscarinic-ACh receptors using Single Photon Emission Computerised Tomography (SPECT) and was utilised to investigate whether cholinergic activity in PTSD is altered. One hundred and sixty eight potential subjects were screened and eleven PTSD subjects were enrolled in the IDEX SPECT study. Three healthy non-PTSD control subjects also completed the study. Due to technical complications only the data obtained from eight PTSD and two control subjects was available for analysis. Imaging data for 2 further healthy non-PTSD control subjects were obtained from another study. Sixteen subjects were enrolled in the donepezil open label study (assessed at baseline, Week 2, 6 and 10). Nine PTSD subjects completed the 10-week trial and seven withdrew prematurely (at or after Week 2) due to side effects or a worsening of PTSD symptoms. For the IDEX SPECT study, a voxel-by-voxel statistical analysis of the PTSD subject group versus the control group showed both areas of reduced and increased IDEX uptake. Significant clusters in the PTSD group with a reduced IDEX uptake centred around the bilateral hippocampus, left insula and right precuneus, while increased IDEX uptake appeared in the caudate head. For the donepezil study, in the per-protocol analysis (including only the 9 subjects that completed the protocol), all psychological assessments revealed a difference between the totals obtained at the Week 10 visit compared to those at the Baseline visit and the improvement was in the order of 51%. The intention-to-treat analysis (including all 16 subjects), a repeated measures Analysis of Variance (ANOVA) with a mixed models approach showed that all psychological measures demonstrated statistically significant benefits of the treatment. All subjects who completed the protocol recounted considerable improvement in their overall PTSD symptom profile, which covered symptoms in each of the three clusters. The results of the IDEX SPECT study suggest that alterations in ACh binding in PTSD are evident and may begin to explain a part of the altered cognitive symptomatology apparent in this condition. The pilot open label donepezil trial provided some preliminary evidence that treatment with an AChEI can lessen the intrusions and distress associated with traumatic memories in people with PTSD. / http://proxy.library.adelaide.edu.au/login?url= http://library.adelaide.edu.au/cgi-bin/Pwebrecon.cgi?BBID=1374974 / Thesis (M.Med.Sc.) -- University of Adelaide, School of Medicine, 2009

Submitted by Noeme Timbo (noeme.timbo@metodista.br) on 2017-06-01T18:55:08Z No. of bitstreams: 1 Celia Mendes de Sousa.pdf: 1112765 bytes, checksum: c120510735266288b8fb36111eeaa8ce (MD5) / Made available in DSpace on 2017-06-01T18:55:08Z (GMT). No. of bitstreams: 1 Celia Mendes de Sousa.pdf: 1112765 bytes, checksum: c120510735266288b8fb36111eeaa8ce (MD5) Previous issue date: 2017-05-17 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / This study aimed to investigate violence against women as a risk factor for the development of Post Traumatic Stress Disorder (PTSD) and its associations with the psychodynamics of these subjects. The participants were five women, aged over 18 years, victims of violence and attended at a Reference and Support Center for Women in the metropolitan region of São Paulo. At first, a questionnaire was used to collect sociodemographic data, past history of the subject and crime (violence suffered). The other instruments used were: the Childhood Trauma Questionnaire (QUESI), the Traumatic Stress Symptom Screening Instrument (Portuguese version of the Screen for Posttraumatic Stress Symptoms - SPTSS) And the Thematic Apperception Test. For the development of the present study the qualitative descriptive combined with a quantitative analysis was carried out as a research method, based on the data obtained in the questionnaire and the scale. The results indicate that four of the five participants present symptoms compatible with the disorder, confirming the hypothesis that the violence committed against women contributes to the development of symptoms related to Post Traumatic Stress Disorder, evidencing itself as one of the risk factors For the occurrence of the disorder. The experience of the situation of violence in a chronic and / or prolonged way appears as aggravating in the appearance and maintenance of the symptoms; On the other hand, social support, favorable family history and perception of aggression as violence and crime are considered as protective factors in this condition. / Este estudo teve como objetivo investigar a violência contra a mulher como fator de risco para o desenvolvimento do Transtorno de Estresse Pós-Traumático (TEPT) e suas associações com a psicodinâmica destes sujeitos. Os participantes foram cinco mulheres, com idade acima de 18 anos, vítimas de violência e atendidas em um Centro de Referência e Apoio à Mulher da região metropolitana de São Paulo. Num primeiro momento foi aplicado um questionário para coleta de dados sociodemográficos, história passada do sujeito e o crime (violência sofrida). Os demais instrumentos utilizados foram: o Childhood Trauma Questionnaire (Questionário Sobre Traumas na Infância (QUESI) – tradução para o português), o Instrumento de Rastreio para Sintomas de Estresse Pós-Traumático (versão em português do Screen for Posttraumatic Stress Symptoms – SPTSS) e o Teste de Apercepção Temática. Para o desenvolvimento do presente estudo adotou-se como método de pesquisa o descritivo-qualitativo combinado a uma análise quantitativa, realizada a partir dos dados obtidos no questionário e na escala. Os resultados apontam que quatro das cinco participantes apresentam sintomas compatíveis com o transtorno, confirmando a hipótese de que a violência cometida contra a mulher contribui para o desenvolvimento de sintomas relativos ao Transtorno de Estresse Pós-Traumático, evidenciando-se como um dos fatores de risco para a ocorrência do transtorno. A vivência da situação de violência de forma crônica e/ou prolongada aparece como agravante no surgimento e manutenção dos sintomas; por outro lado, o apoio social, histórico familiar favorável e percepção das agressões enquanto violência e crime são tidos como fatores protetivos nesta condição.

Researchers examining issues of recent veterans of military conflicts in Iraq and Afghanistan have found evidence of psychological distress and difficulty adjusting to civilian life post-deployment. Changes in educational benefits offered to veterans will likely facilitate greater numbers of veterans to enter academia in the coming years. This survey of 49 college student veterans at a large Midwestern university was designed to reveal the frequency and intensity of psychological distress, PTSD and alcohol misuse. Relationships between these constructs and the constructs of social support, stigma and barriers to psychological care, life satisfaction, traumatic experiences, attitudes toward help seeking, and service utilization are reported. A history of mental health service utilization since military service was reported by many respondents. PTSD and alcohol misuse symptoms were reported by many college student veterans and incidence in this sample was greater than the incidence previously reported in the literature on veterans. Stigma was found to be negatively correlated with attitudes toward help seeking. Post deployment social support was found to be negatively associated with psychological distress and positively associated with service utilization. Implications and limitations of these findings are presented and future directions for research and intervention are discussed.

abstract: Major Depressive Disorder (MDD) and Posttraumatic Stress Disorder (PTSD) are highly prevalent illnesses that can result in profound impairment. While many patients with these disorders present in primary care, research suggests that physicians under-detect and suboptimally manage MDD and PTSD in their patients. The development of more effective training interventions to aid primary care providers in diagnosing mental health disorders is of the utmost importance. This research focuses on evaluating computer-based training tools (Avatars) for training family physicians to better diagnose MDD and PTSD. Three interventions are compared: a "choice" avatar simulation training program, a "fixed" avatar simulation training program, and a text-based training program for training physicians to improve their diagnostic interviewing skills in detecting and diagnosing MDD and PTSD. Two one-way ANCOVAs were used to analyze the differences between the groups on diagnostic accuracy while controlling for mental health experience. In order to assess specifically how prior mental health experience affected diagnostic accuracy the covariate of prior mental health experience was then used as an independent variable and simple main effects and pairwise comparisons were evaluated. Results indicated that for the MDD case both avatar treatment groups significantly outperformed the text-based treatment in diagnostic accuracy regardless of prior mental health experience. For the PTSD case those receiving the fixed avatar simulation training more accurately diagnosed PTSD than the text-based training group and the choice-avatar training group regardless of prior mental health experience. Confidence ratings indicated that the majority of participants were very confident with their diagnoses for both cases. Discussion focused on the utility of avatar technology in medical education. The findings in this study indicate that avatar technology aided the participants in diagnosing MDD and PTSD better than traditional text-based methods employed to train PCPs to diagnose. Regardless of experience level the fixed avatar group outperformed the other groups for both cases. Avatar technology used in diagnostic training can be user-friendly and cost-effective. It can also have a world-wide reach. Additional educational benefit could be provided by using automated text analysis to provide physicians with feedback based on the extent to which their case diagnostic summaries cover relevant content. In conclusion, avatar technology can offer robust training that could be potentially transferred to real environment performance. / Dissertation/Thesis / Ph.D. Counseling Psychology 2012