Magister Psychologiae - MPsych / South Africans are exposed to many traumatic events and exposure to such events is associated with negative emotional and behavioural outcomes. However, there are those who are still able to remain psychologically well amidst their difficulties. Resilience is the motivation to be strong in the face of unwarranted demands and this study proposes that it could serve as a buffer against the harmful effects of traumatic events. It is assumed that traumatic events present with demanding circumstances and further that resilience plays a role in the relationship between trauma, the challenges these events present and one’s ability to function in these circumstances. Furthermore, ‘race’ may have a particular influence on this relationship as the level and severity of trauma among different ‘racial’ groups may vary. The link between resilience and trauma has been investigated, but little focus has been given to how ‘race’ may influence this relationship among students in the South African context. The aim of the current study was therefore to investigate the interaction between these three variables and add to existing knowledge related to resilience. Constructs related to resilience include sense of coherence, potency, hardiness, learned resourcefulness and fortitude. The two ‘racial’ groups included in the sample include ‘African’ and ‘Coloured’ students (categories created by the past apartheid government). Resilience was measured by the Resilience Scale for Adults (RSA), trauma was measured by the Harvard Trauma Scale (HTS) and violence exposure was measured by the Childhood Exposure to Community Violence Scale (CECV). Participants included 249 students at the University of the Western Cape. Results indicate that ‘Coloured’ students report similar levels of violence exposure and trauma symptoms as ‘African’ students do. ‘Coloured’ students report higher scores on overall resilience and resilience sub-scales (except the structured style sub-scale) than ‘African’ students as measured on the RSA. With regard to the trauma versus no trauma groups, the results indicate that ‘African’ students who form part of the no trauma group score higher on resilience than those who form part of the trauma group and within the trauma group ‘Coloured’ students score higher on resilience than ‘African’ students. In analyses amongst the high and the low trauma groups, the results indicate that those who form part of the low trauma group score higher on resilience than those who are among the high trauma group; ‘African’ students who form part of the low trauma group score higher on resilience than those who form part of the high trauma group; and ‘Coloured’ students who form part of the low trauma group score higher on resilience than those who form part of the high trauma group. The results yielded in the current study are both similar to and differ from findings presented in previous studies and highlight the complexity of the construct of resilience. Limitations of the study are outlined and recommendations for future research are also provided.

Background: Justice-involved populations report a higher than average number of pre-incarceration stressful life events. However, few studies have described stressful life events which occur during incarceration, explored gender differences in these events, or evaluated the effect of these events on well-being. Method: This study draws from a sample of male and female adults incarcerated in 6 prison facilities across two states (n = 160) to identify the number and type of stressful life events they experienced during incarceration, gender differences in stressful events, and the relationship between stressful life events and markers of well-being (i.e., depression, hopelessness, loneliness, suicidality). We also examined whether perceived social support would buffer the relationship between stressful events and well-being outcomes. Results: Participants on average reported experiencing 4 stressful life events during their current incarceration, the most common being relocation to another cell and being made fun of/insulted by someone in the prison. There were few gender differences in types of events experienced. Regression analyses showed that stressful life events were associated with more loneliness, as well as suicidality, but only when participants had low perceived social support. Conclusions: Stressful life events, and drawing on social support networks to cope with stress, should be addressed in the context of correctional treatments to reduce suicide risk during incarceration.

Some people are genetically more vulnerable to stress than others, leading them towards poorer outcomes following stressful events. Mothers' vulnerability to stress may, in turn, influence their children, leading their children towards poor outcomes as well. A biological marker of vulnerability to stress may indicate mothers who are at greater risk for experiencing parenting stress, depression, and less support of the infant's emotional development, and infants who are at greater risk for development of poor emotion regulation and behavior problems. Taste sensitivity to propylthiouracil (PROP) is proposed as a biological marker of stress vulnerability in mothers and children. This research used a bioecological approach to examine extant data from two previous longitudinal studies, both with child and mother data from maternal interviews and video-recorded observations of mother-child interaction. Participants included 121 low-income and 102 middle-income mother-child pairs who were studied for presence of the biological marker in relation to stressful life events, parenting stress, depression, and lower support of infants' emotions. Children were studied for presence of the biological marker in relation to their development of emotion regulation and their later behavior problems. Results revealed that PROP taste sensitivity, as tested in this study, is not likely to be a useful biological marker of higher vulnerability to stress. Although results flowed in the hypothesized direction, few reached statistical significance and most were of small effect size. For depression, results supported previous research, although with smaller effect sizes. In addition, results depended on the sample and source of stress. For low-income mothers the source of stress was stressful life events. For the middle-income sample the source of stress was parenting stress, specifically mother-child dysfunctional interaction. Among mothers with higher PROP taste sensitivity, those from the low-income sample reported more depression whether stressful events were higher or lower, whereas those from the middle-income sample reported more depression when parenting stress, particularly poor mother-child dyadic interaction, was higher. From both samples, mothers' parenting stress or depression at 14 months predicted children's later behavior problems when they were school-age. Children with lower PROP taste sensitivity were more emotionally regulated with their mothers. Because the results were consistent and suggestive, although not conclusive enough to warrant the use of PROP as a biological marker, future research should examine individual situational factors under which PROP taste sensitivity is related to stress vulnerability.

The objective of this study was to examine the combined moderating effects of life stress and loneliness on the association between social problem solving ability (SPS) and suicidal behaviors. We assessed SPS, suicidal behavior, loneliness, and stressful life events in a sample of 385 ethnically diverse college students. Overall, only loneliness moderated the association between SPS and suicidal behaviors. Across ethnic groups, loneliness moderated the association between SPS and suicidal behavior for Blacks, Whites, and Asians; life stress was a moderator for Hispanics. For most individuals, loneliness increases the strength of the association between poor problem-solving and suicidal behaviors. For Hispanics, life stress exacerbates this relationship. Ethnically-specific prevention strategies targeting loneliness and life stress may promote effective problem-solving, reducing suicide risk.

Suicidal Behavior in the U.S. Army is a problem that persists despite significant efforts to promote help-seeking behaviors and the investment of millions of dollars to develop resilience-building interventions. Evidence-based literature supports the use of reasons for living as a protective factor against suicidal behavior in clinical and nonclinical samples, yet it has rarely been studied in an active duty (AD) Army population. This study examined the relationship between self-reported reasons for living and self-reported suicidal behavior, to determine if high levels of reasons for living correlated with low risk of suicidal behavior, over and above demographics, depression, stressful life events, and social support, using standardized questionnaires. The study sample consisted of 244 AD Army soldiers attending the Warrior Leadership Course in Germany. The results analysis showed that reasons for living were inversely related to suicidal behavior among this sample. Although African American soldiers scored higher on measures of reasons for living and suicidal behavior, demographic variables did not significantly predict suicidal behavior. Reasons for living accounted for a unique amount of variance in suicidal behavior; however, depression, stressful life events, and social support were better predictors. This study demonstrates the benefits of incorporating reasons for living in military research and practice, as efforts are made to identify AD Army personnel at risk for suicide. The study findings also support the claim that examining protective and risk factors supersedes efforts to study risk factors alone. It promotes positive social change by informing efforts to develop comprehensive suicide prevention policies, programs, and procedures aimed at effectively reducing the rate of suicide in the U.S. Army.

Suicidal Behavior in the U.S. Army is a problem that persists despite significant efforts to promote help-seeking behaviors and the investment of millions of dollars to develop resilience-building interventions. Evidence-based literature supports the use of reasons for living as a protective factor against suicidal behavior in clinical and nonclinical samples, yet it has rarely been studied in an active duty (AD) Army population. This study examined the relationship between self-reported reasons for living and self-reported suicidal behavior, to determine if high levels of reasons for living correlated with low risk of suicidal behavior, over and above demographics, depression, stressful life events, and social support, using standardized questionnaires. The study sample consisted of 244 AD Army soldiers attending the Warrior Leadership Course in Germany. The results analysis showed that reasons for living were inversely related to suicidal behavior among this sample. Although African American soldiers scored higher on measures of reasons for living and suicidal behavior, demographic variables did not significantly predict suicidal behavior. Reasons for living accounted for a unique amount of variance in suicidal behavior; however, depression, stressful life events, and social support were better predictors. This study demonstrates the benefits of incorporating reasons for living in military research and practice, as efforts are made to identify AD Army personnel at risk for suicide. The study findings also support the claim that examining protective and risk factors supersedes efforts to study risk factors alone. It promotes positive social change by informing efforts to develop comprehensive suicide prevention policies, programs, and procedures aimed at effectively reducing the rate of suicide in the U.S. Army.

Psychological stress is a major risk factor for cardiovascular diseases. While the relevance of early life stress, such as that which is due to child maltreatment (CM), is well known to impact individual stress responses in the long-term, and data on the interplay between CM and stressful events in adulthood on cardiovascular health are sparse. Here, we aimed to assess how stressful life events in adulthood are associated with cardiovascular health infarction in later life and whether this association is independent of CM. In a cross-sectional design, a probability sample of the German population above the age of 14 was drawn using different sampling steps. The final sample included 2510 persons (53.3% women, mean age: 48.4 years). Participants were asked about sociodemographic factors, adult life events, CM, and health conditions in adulthood. Results indicate that the number of experienced adverse life events in adulthood is associated with significantly increased odds for obesity (Odds Ration (OR)women = 1.6 [1.3; 2.0], ORmen = 1.4 [1.1; 1.9]), diabetes (ORwomen = 1.5 [1.1; 2.1], ORmen = 1.5 [1.1; 2.3]) and myocardial infarction (ORwomen = 2.1 [1.0; 4.3], ORmen = 1.8 [1.1; 2.8]). This association is not moderated by the experience of CM, which is associated with cardiovascular problems independently. Taken together, adult stressful life events and CM are significantly and independently associated with cardiovascular health in men and women in the German population in a dose-dependent manner. General practitioners, cardiologists and health policy-makers should be aware of this association between psychosocial stressors during childhood and adulthood and cardiovascular health.

Objectif: Examiner l’association entre l'exposition aux évènements stressants de la vie et le cancer du poumon. Méthodes: Les données proviennent d’une étude cas-témoins, menée chez les hommes et les femmes vivant dans la région métropolitaine de Montréal entre 1996 et 2001. Le cancer du poumon d’un cas éligible devait être confirmé histologiquement à l’un des 18 hôpitaux de cette région. Les témoins ont été sélectionnés aléatoirement de la liste électorale du Québec et ont été appariés au cas par fréquence de groupes d'âge et par sexe. Un questionnaire a été administré en entrevue pour recueillir les données, dont l’évaluation de huit évènements stressants de la vie par le participant. Si le participant avait vécu un évènement stressant ciblé durant les six dernières années, il devait aussi coter cet évènement sur une échelle de trois points. La régression logistique non conditionnelle a été utilisée pour estimer les rapports de cotes ainsi que leurs intervalles de confiance à 95%. Des analyses par sexe, niveau de tabagisme et par type histologique ont été réalisées. Nous avons aussi analysé l’association entre le cancer du poumon et le nombre total d'évènements, les évènements de perte et les évènements socioéconomiques, ainsi que chaque évènement individuellement. Les analyses des scores d'impact autoévalués et avec un score externe de perception, ont également été menées. Résultats: La population de ce projet comprend 1061 cas et 1422 témoins, âgés de 35 à 70 ans. Les participants inclus avaient répondu aux sections du questionnaire portant sur les facteurs de style de vie et sur l'historique de tabagisme. Dans l'ensemble, nous n’avons pas observé d’association entre le cancer du poumon et l'exposition aux évènements stressants de la vie. Nous avons observé une diminution du risque pour les évènements socioéconomiques autoévalués comme peu stressants (RC=0,50; IC 95%= 0,31 - 0,81). Conclusion: Nos résultats suggèrent que les évènements socioéconomiques sont associées à un risque réduit si ces évènements sont considérés comme peu stressant. / Objective: To examine exposure to stressful life events in relation to lung cancer risk. Methods: Our research used data from a case-control study conducted in Montreal from 1996 to 2001. Cases were diagnosed with histologically confirmed incident lung cancer at one of 18 Montreal-area hospitals. Controls were randomly selected from the Quebec electoral list and frequency matched to the distribution of cases by sex and 5 year age groups. Data was collected on sociodemographic characteristics, lifetime smoking, and lifestyle factors including 8 stressful life events. Participants indicated the stressful life events they experienced over the past six years, and an appraisal of their level of stress due to each event on a three-point scale. Unconditional logistic regression was used to estimate adjusted odds ratios and 95% confidence intervals. Each stressful life event was analyzed individually as well as in grouped variables measuring total number of events, loss events and socioeconomic events. Analyses of self-appraised impact scores were also conducted; additionally an external perceived stress score was also employed. Results: 1061 cases and 1422 population controls were included in the analyses. Overall, we observed no association between lung cancer and stressful life events. A decrease in risk for socioeconomic events self-appraised as not very stressful was observed (OR, 0.50; 95% CI, 0.31, 0.81), which included job loss, increase in debt, and move to another city. Conclusion: Our results suggest that socioeconomic events, deemed not very stressful, may reduce the risk of lung cancer.

The 5-HTT gene (SLC6A4) is regulated by a common polymorphism in the promoter region (5-HTTLPR), which has functional consequences. Two major alleles have been observed and shown to have differential transcriptional activity with the long (L) allele having greater gene expression than the short (S) allele. 5-HTTLPR appears to modulate depression, anxiety and personality traits such as neuroticism. Additionally, a significant influence of 5-HTTLPR genotype on amygdala reactivity in response to fearful stimuli has been reported. Moreover, 5-HTTLPR seems to impact on the role of stressful life events (SLEs) in the development of depression. An elevated risk of depression and suicidal behaviors has been found in carriers of at least one low expressing S allele who had experienced SLEs, suggesting a gene x environment interaction. However, a recent meta-analysis showed that several findings failed to replicate this finding. Since genetic polymorphisms of the dopaminergic and serotonergic neurotransmission interact at the molecular, analyses with another polymorphism of the dopaminergic system, the dopamine D4 receptor (DRD4) was included to consider these likely gene-gene interactions (epistasis). The aim of this series of studies was to investigate the role 5-HTTLPR and SLEs on the endocrine stress response in different age samples. While newborns have been examined by a heel prick, stress responses were provoked in children (8-12 yrs) and younger adults (19-31 yrs) and older adults (54-68 yrs.) with the Trier Social Stress Test (TSST). The Life History Calendar (LHC) and Life Events Questionnaire (LEQ) were used to acquire data on SLEs. While in newborns the S/S genotype showed a significantly higher acute endocrine stress response than L/L or S/L genotypes, no significant difference between genotype groups was found in children. In the younger adult sample, the genotype impacted on cortisol stress responsiveness was reversed. Adults carrying the more active L allele of the 5-HTTLPR polymorphism showed a significantly larger cortisol response to the TSST than individuals carrying at least one of the lower expressing S allele. In older adults, no significant difference between genotype groups was found. However, results point in the same direction with showing highest cortisol response in individuals with L/L genotype. These data suggest that the association between 5-HTTLPR and endocrine stress reactivity seems to alter across lifespan, more specific the effects of genotype turns around. In addition, a significant interaction effect of 5-HTTLPR and SLEs has been found in the sample of younger adults, i.e. that early SLE as well as a severe number SLEs across the entire lifespan seem to modulate the interaction between HPA axis activity and 5-HTTLPR genotype. Additionally, a DRD4 by 5-HTTLPR interaction emerged which point to independent and joint effects of these polymorphisms on stress responsivity with regard to the concept of genegene interaction.

Introduction : Identifier des mécanismes sous-tendant l’association entre les évènements stressants et la dépression est essentiel pour développer des interventions de santé publique ciblées. Pour faire face aux évènements stressants, les individus adoptent des styles d'adaptation qui sont associés différemment aux symptômes dépressifs. Cependant, aucune étude n'a évalué si le style d'adaptation est médiateur et/ou modérateur de cette association. Objectifs : Examiner chacun des styles soit l’adaptation centrée sur le problème, l’adaptation centrée sur les émotions et l’adaptation évitante comme médiateur et/ou modérateur de l’association entre les évènements stressants et les symptômes dépressifs chez les jeunes adultes. Méthodes : Nicotine Dependence in Teens (NDIT) est une étude longitudinale portant sur 1294 participants recrutés en secondaire I dans 10 écoles secondaires de Montréal, Québec entre 1999–2000. L’analyse actuelle utilise les données (n = 782) de questionnaires auto-rapportés recueillis après le secondaire entre 2011–2012. En utilisant la décomposition en quatre parties de VanderWeele, l’effet total d’évènements stressants sur les symptômes dépressifs a été décomposé en composantes représentant la modération uniquement, la médiation uniquement, l’interaction médiée et ni la médiation ni la modération par chaque style d’adaptation. Résultats : Nous avons observé une modération par l’adaptation centrée sur le problème (β ̂(IC à 95%)=-1.51(-2.22, -1.06)) et une médiation (0.15(0.05, 0.17)) et une modération (1.16(1.05, 1.68) par l’adaptation centrée sur les émotions. L’adaptation évitante n’a ni médiatisé ni modéré cette association. Ainsi, les individus ayant une adaptation centrée sur le problème présentent moins de symptômes dépressifs lorsqu’ils sont exposés à plus d’évènements stressants. Ceux ayant une adaptation centrée sur les émotions présentent plus de symptômes dépressifs. Conclusion : Ces résultats suggèrent que les interventions préventives contre la dépression chez les jeunes adultes devraient inclure des éléments pour renforcer les stratégies d'adaptation centrées sur le problème et pour minimiser les stratégies d'adaptation centrées sur les émotions. / Introduction: Identifying potential mechanisms underpinning the association between stressful life events and depression is key to developing targeted public health interventions. To cope with stressful experiences, individuals adopt coping styles which are differentially associated with depressive symptoms. However, no study has assessed whether coping style mediates and/or moderates this association. Objectives: To examine each of problem-focused, emotion-focused and avoidant coping style as a mediator and/or moderator of the association between stressful life events and depressive symptoms in young adults. Methods: The Nicotine Dependence in Teens (NDIT) is a longitudinal study including 1294 participants recruited in grade 7 from 10 high schools in Montreal Quebec between 1999–2000. The current analysis uses data (n = 782) from self-report questionnaires collected post-high school between 2011–2012. Using VanderWeele’s four-way decomposition approach, the total effect of stressful life events on depressive symptoms was decomposed into components representing moderation only, mediation only, mediated interaction and neither mediation nor moderation by each coping style. Results: We observed moderation by problem-focused coping (β ̂(95%CI)=-1.51(-2.22, -1.06)) and mediation (0.15(0.05, 0.17)) and moderation (1.16(1.05, 1.68) by emotion-focused coping. An avoidant coping style neither mediated nor moderated this association. Thus, individuals reporting more problem-focused coping experienced fewer depressive symptoms when exposed to more stressful life events; those reporting more emotion-focused coping experienced more depressive symptoms. Conclusion: These results suggest that preventive interventions for depression in young adults should include components to reinforce problem-focused coping strategies and should minimize negative emotion-focused coping strategies.