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Im Rahmen des Postgradual-Studienganges (PGS) „Toxikologie und Umweltschutz“ wird das interaktive Lernprogramm „Toxnetz-Explorer“ entwickelt. Anhand von Grafiken, Animationen und unterstützenden Texten sollen die wichtigsten Funktionen des menschlichen Körpers und einzelner Organe sowie der Zusammenhang dieser mit toxikologischen Vorgängen veranschaulicht werden. Die vorliegende Arbeit stellt die Basis des Abschnittes über die Niere für das Lernprogramms „Toxnetz-Explorer“ dar. Die Nieren sind die zentralen Ausscheidungsorgane des menschlichen Körpers. Alle löslichen Verbindungen werden in der Niere filtriert, dem Körper über unterschiedliche Prozesse zurückgeführt, metabolisiert oder ausgeschieden. Darüber hinaus besitzt die Niere weitere regulierende Aufgaben, wie beispielsweise die Regulation des Wasser-Elektrolyt- oder des Säure-Haushaltes. Sie sind ebenfalls für die Autoregulation des renalen Blutdruckes und die Synthese von verschiedenen Substanzen verantwortlich. Auf Grund dieser vielen und wichtigen Funktionen und der hohen Durchblutungsrate sowie der Aufkonzentrierung von Substanzen stellen die Nieren ein attraktives Ziel für ein große Anzahl an toxischen Stoffen dar, welche an die verschiedenen renalen Funktionseinheiten eine Schädigung bewirken können. Ziel dieser Arbeit ist die anschauliche Darstellung des anatomischen Aufbaus der Niere, der normalen renalen Funktionen und Aufgaben im menschlichen Körper, sowie eine Zusammenstellung verschiedener nephrotoxischen Substanzen und deren spezifischen Schädigungsmechanismen.

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After the students in high school have learned to integrate a function, the calculation of the volume of a solid of revolution, like a rotated parabola, is taken as a good applied example. The next step is to calculate the volume of an object of reality which is interpreted as a solid of revolution of a given function f(x). The students do all these calculations in the same way and get the same result. Consequently the teachers can easily decide if a result is right or wrong. If the students have learned to work with a graphical or CAS calculator, they can calculate the volume of solids of revolution in reality by modelling a possible fitted function f(x). Every student has to decide which points of the curve that generates the solid of revolution can be taken and which function will suitably fit the curve. In Austrian high schools teachers use GeoGebra as a software which allows you to insert photographs or scanned material in the geometric window as a background picture. In this case the student and the teacher can control if the graph of the calculated function will fit the generating curve in a useful way.

After the students in high school have learned to integrate a function, the calculation of the volume of a solid of revolution, like a rotated parabola, is taken as a good applied example. The next step is to calculate the volume of an object of reality which is interpreted as a solid of revolution of a given function f(x). The students do all these calculations in the same way and get the same result. Consequently the teachers can easily decide if a result is right or wrong. If the students have learned to work with a graphical or CAS calculator, they can calculate the volume of solids of revolution in reality by modelling a possible fitted function f(x). Every student has to decide which points of the curve that generates the solid of revolution can be taken and which function will suitably fit the curve. In Austrian high schools teachers use GeoGebra as a software which allows you to insert photographs or scanned material in the geometric window as a background picture. In this case the student and the teacher can control if the graph of the calculated function will fit the generating curve in a useful way.

Research on mixed devices in web surveys is in its infancy. Using a randomized experiment, we investigated device effects (desktop PC, tablet and mobile phone) for six response formats and four different numbers of scale points. N=5,077 members of an online access panel participated in the experiment. An exact test of measurement invariance and Composite Reliability were investigated. The results provided full data comparability for devices and formats, with the exception of continuous Visual Analog Scale (VAS), but limited comparability for different numbers of scale points. There were device effects on reliability when looking at the interactions with formats and number of scale points. VAS, use of mobile phones and five point scales consistently gained lower reliability. We suggest technically less demanding implementations as well as a unified design for mixed-device surveys.

This volume contains the papers presented at the International Conference on “Models in Developing Mathematics Education” held from September 11-17, 2009 at The University of Applied Sciences, Dresden, Germany. The Conference was organized jointly by The University of Applied Sciences and The Mathematics Education into the 21st Century Project - a non-commercial international educational project founded in 1986. The Mathematics Education into the 21st Century Project is dedicated to the improvement of mathematics education world-wide through the publication and dissemination of innovative ideas. Many prominent mathematics educators have supported and contributed to the project, including the late Hans Freudental, Andrejs Dunkels and Hilary Shuard, as well as Bruce Meserve and Marilyn Suydam, Alan Osborne and Margaret Kasten, Mogens Niss, Tibor Nemetz, Ubi D’Ambrosio, Brian Wilson, Tatsuro Miwa, Henry Pollack, Werner Blum, Roberto Baldino, Waclaw Zawadowski, and many others throughout the world. Information on our project and its future work can be found on Our Project Home Page http://math.unipa.it/~grim/21project.htm It has been our pleasure to edit all of the papers for these Proceedings. Not all papers are about research in mathematics education, a number of them report on innovative experiences in the classroom and on new technology. We believe that “mathematics education” is fundamentally a “practicum” and in order to be “successful” all new materials, new ideas and new research must be tested and implemented in the classroom, the real “chalk face” of our discipline, and of our profession as mathematics educators. These Proceedings begin with a Plenary Paper and then the contributions of the Principal Authors in alphabetical name order. We sincerely thank all of the contributors for their time and creative effort. It is clear from the variety and quality of the papers that the conference has attracted many innovative mathematics educators from around the world. These Proceedings will therefore be useful in reviewing past work and looking ahead to the future.

This volume contains the papers presented at the International Conference on “Turning Dreams into Reality: Transformations and Paradigm Shifts in Mathematics Education” held from September 11-17, 2011 at Rhodes University, Grahamstown, South Africa. The Conference was organized jointly by Rhodes University and The Mathematics Education into the 21st Century Project - an international educational project founded in 1986. Our Project is dedicated to the improvement of mathematics education world-wide through the publication and dissemination of innovative ideas. Many prominent mathematics educators have supported and contributed to the project, including the late Hans Freudental, Andrejs Dunkels and Hilary Shuard, as well as Bruce Meserve and Marilyn Suydam, Alan Osborne and Margaret Kasten, Mogens Niss, Tibor Nemetz, Ubi D’Ambrosio, Brian Wilson, Tatsuro Miwa, Henry Pollack, Werner Blum, Roberto Baldino, Waclaw Zawadowski, and many others throughout the world. Information on our project and its future work can be found on our Project home page http://math.unipa.it/~grim/21project.htm . In this year, 2011, we celebrate the 25th anniversary of the founding of our Project, when Manmohan Singh Arora suggested the idea to Fayez Mina and myself around a swimming pool in Bahrain (of all places!) That first meeting was, however, typical of the multi-cultured and global character of our Project and it’s subsequent conferences throughout the world. These Proceedings begin with the Plenary Papers and then the other contributions in alphabetical name order of the principal authors. We sincerely thank all of the contributors for their time and creative effort. It is clear from the variety and quality of the papers that the conference has attracted many innovative mathematics educators from around the world.

This volume contains the papers presented at the International Conference on “Models in Developing Mathematics Education” held from September 11-17, 2009 at The University of Applied Sciences, Dresden, Germany. The Conference was organized jointly by The University of Applied Sciences and The Mathematics Education into the 21st Century Project - a non-commercial international educational project founded in 1986. The Mathematics Education into the 21st Century Project is dedicated to the improvement of mathematics education world-wide through the publication and dissemination of innovative ideas. Many prominent mathematics educators have supported and contributed to the project, including the late Hans Freudental, Andrejs Dunkels and Hilary Shuard, as well as Bruce Meserve and Marilyn Suydam, Alan Osborne and Margaret Kasten, Mogens Niss, Tibor Nemetz, Ubi D’Ambrosio, Brian Wilson, Tatsuro Miwa, Henry Pollack, Werner Blum, Roberto Baldino, Waclaw Zawadowski, and many others throughout the world. Information on our project and its future work can be found on Our Project Home Page http://math.unipa.it/~grim/21project.htm It has been our pleasure to edit all of the papers for these Proceedings. Not all papers are about research in mathematics education, a number of them report on innovative experiences in the classroom and on new technology. We believe that “mathematics education” is fundamentally a “practicum” and in order to be “successful” all new materials, new ideas and new research must be tested and implemented in the classroom, the real “chalk face” of our discipline, and of our profession as mathematics educators. These Proceedings begin with a Plenary Paper and then the contributions of the Principal Authors in alphabetical name order. We sincerely thank all of the contributors for their time and creative effort. It is clear from the variety and quality of the papers that the conference has attracted many innovative mathematics educators from around the world. These Proceedings will therefore be useful in reviewing past work and looking ahead to the future.

This volume contains the papers presented at the International Conference on “Turning Dreams into Reality: Transformations and Paradigm Shifts in Mathematics Education” held from September 11-17, 2011 at Rhodes University, Grahamstown, South Africa. The Conference was organized jointly by Rhodes University and The Mathematics Education into the 21st Century Project - an international educational project founded in 1986. Our Project is dedicated to the improvement of mathematics education world-wide through the publication and dissemination of innovative ideas. Many prominent mathematics educators have supported and contributed to the project, including the late Hans Freudental, Andrejs Dunkels and Hilary Shuard, as well as Bruce Meserve and Marilyn Suydam, Alan Osborne and Margaret Kasten, Mogens Niss, Tibor Nemetz, Ubi D’Ambrosio, Brian Wilson, Tatsuro Miwa, Henry Pollack, Werner Blum, Roberto Baldino, Waclaw Zawadowski, and many others throughout the world. Information on our project and its future work can be found on our Project home page http://math.unipa.it/~grim/21project.htm . In this year, 2011, we celebrate the 25th anniversary of the founding of our Project, when Manmohan Singh Arora suggested the idea to Fayez Mina and myself around a swimming pool in Bahrain (of all places!) That first meeting was, however, typical of the multi-cultured and global character of our Project and it’s subsequent conferences throughout the world. These Proceedings begin with the Plenary Papers and then the other contributions in alphabetical name order of the principal authors. We sincerely thank all of the contributors for their time and creative effort. It is clear from the variety and quality of the papers that the conference has attracted many innovative mathematics educators from around the world.