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When reading the Bible in an independent way, i.e., not through the lenses of any official Church dogma, one is amazed by the many voices that come through to us. Add to this variety the literaiy finds from Nag Hammadi, as well as the Dead Sea Scrolls, then the question now confronting many spiritual pilgrims is how it came about that these obviously diverse theologies, represented in the socalled Old and New Testaments, were moulded into only one "orthodox" result. In what way and to what degree were the many Christian groups different and distinctive from one another, as well as from other Jewish groups? Furthermore, what was the influence of other religions, Judaism, the Mysteries, Gnostics and Philosophers on the development, variety of groups and ultimately 021 the consolidation of "orthodox" soteriology? / Systematic Theology and Theological Ethics / M.Th. (Systematic Theology)

Submitted by Gilmar Barros (gilmargomesdebarros@gmail.com) on 2015-04-24T18:55:36Z No. of bitstreams: 1 DANIEL BAZ DOS SANTOS.pdf: 840231 bytes, checksum: da5b75b0dadd012df868a17e0c935224 (MD5) / Rejected by Vitor de Carvalho (vitor_carvalho_im@hotmail.com), reason: - Nomes nos primeiros campos não podem ser em caixa alta; - Citação incorreta, conferir o tutorial. on 2015-06-12T19:12:55Z (GMT) / Submitted by Gilmar Barros (gilmargomesdebarros@gmail.com) on 2015-06-15T15:04:29Z No. of bitstreams: 1 DANIEL BAZ DOS SANTOS.pdf: 840231 bytes, checksum: da5b75b0dadd012df868a17e0c935224 (MD5) / Rejected by Vitor de Carvalho (vitor_carvalho_im@hotmail.com), reason: Um dos sobrenomes do autor está incorreto. on 2015-06-22T19:17:13Z (GMT) / Submitted by Gilmar Barros (gilmargomesdebarros@gmail.com) on 2015-06-23T16:39:04Z No. of bitstreams: 1 DANIEL BAZ DOS SANTOS.pdf: 840231 bytes, checksum: da5b75b0dadd012df868a17e0c935224 (MD5) / Approved for entry into archive by Vitor de Carvalho (vitor_carvalho_im@hotmail.com) on 2015-07-03T18:25:12Z (GMT) No. of bitstreams: 1 DANIEL BAZ DOS SANTOS.pdf: 840231 bytes, checksum: da5b75b0dadd012df868a17e0c935224 (MD5) / Made available in DSpace on 2015-07-03T18:25:12Z (GMT). No. of bitstreams: 1 DANIEL BAZ DOS SANTOS.pdf: 840231 bytes, checksum: da5b75b0dadd012df868a17e0c935224 (MD5) Previous issue date: 2012 / Esta dissertação analisa o livro Uma história do romance de 30, de Luís Bueno, a partir de conceitos relativos à escrita da história da literatura. Para tanto, busca-se averiguar os artifícios retóricos de sua construção, como narratividade, taxonomia e cânone. Além disso, a partir dos conteúdos expressos pelo objeto analisado, pretende-se discutir uma série de temas relativos à literatura brasileira e sua tradição historiográfica. Sendo assim, estuda-se, por exemplo, a trajetória do romance de 30 enquanto gênero nas histórias da literatura brasileira; pensam-se noções célebres na histografia literária nacional, como a noção, de “sistema” de Antonio Candido, e o nacionalismo literário; entre outras preocupações. / Esa disertación discorre sobre el libro Uma história do romance de 30, de Luís Bueno, partiendo de conceptos que interesan a la historia de la literatura. Para eso, averiguase los artificios retoricos de su construcción, como la narratividad, la taxonomia y el canon. Además, a partir de los contenidos expresados por el objeto analisado, discutese una serie de temas relativos a la literatura brasileña y su tradición historiografica, como por ejemplo, el percurso de la novela de 30, en cuanto género, en las historias de la literatura brasileña; nociones célebres en la historiografia literaria nacional, como la noción de “sistema”, de Antonio Candido, y el nacionalismo literario; entre otras preocupaciones.

Orientadores: Andre Leonardo Chevitarese, Pedro Paulo Abreu Funari / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciencias Humanas / Made available in DSpace on 2018-08-05T17:24:50Z (GMT). No. of bitstreams: 1 Silva_RobertaAlexandrinada_M.pdf: 709742 bytes, checksum: 07d17ed4da3eac86fef561532ed5888a (MD5) Previous issue date: 2006 / Resumo: Este texto analisa a participação da mulher na proposta de Reino de Deus apresentado pelo ministério de Jesus e, ao mesmo tempo, abordar os Movimentos de Jesus e, posteriormente, o cristão fixado nas estruturas de seu tempo e meio. Com a observação das várias expressões sobre o Reino de Deus contida nos textos dos evangelistas pode-se fazer um estudo de gênero entendendo a relação que estes trabalhavam a idéia de Reino de Deus com as mulheres, e como isso era perpassado nos diálogos de Jesus e das comunidades cristãs / Abstract: This text analyzes the participation of woman in the proposal Kingdom of God presented by the department of Jesus and, at the same time, approaches the Movements of Jesus and, subsequently, the Christian set in the structures of his time and half. With the observation of the several expressions about the Kingdom of God contained us texts of the evangelists is able to be done a study of kind understanding the relation that these worked Kingdom of God idea with the women, and as that to be passed us dialogues of Jesus and of the Christian communities / Mestrado / Historia Cultural / Mestre em História

A ênfase do estudo é ver a representação do período de 30-60 na obra drummondiana; ou seja, a incorporação da realidade brasileira na subjetividade lírica a partir de alguns pontos específicos: certos traços do país-colônia e do país-burguês na construção da figura do gauche; o discurso da ditadura de Vargas; os novos meios de produção e recepção da arte na década de 40; e o desenvolvimentismo de JK. / Our approach of Drummonds work aims to study the way in which the decades of 30-60 are represented in his poetry; or the way by which the Brazilian reality is incorporated in the subjectivity of the poet starting from some particular elements: some aspects regarding realities of the country that are due to Brazils colonialist past, and some aspects that are linked to the modern developments of the country, both seen in the building of the gauches 3 portrait; the dictatorial speech of the Vargas era; new production and reception means of art in the decade of 40s; and the effort towards development in the government of JK.

Esta pesquisa tem como enfoque as personagens femininas de Graciliano Ramos em suas obras Caetés, São Bernardo, Angústia, Vidas Secas e Infância. Partindo dos conceitos de Antonio Candido sobre estrutura e função, busca-se analisar como a construção literária se relaciona com os dados sociais e históricos da época em que os livros foram escritos e/ou publicados, a década de 1930. A partir das análises feitas, desenvolve-se a ideia da importância dessas personagens que, mesmo deixadas em segundo plano, são essenciais para a construção dos textos literários. / The following research focuses on the female characters of Graciliano Ramos in his works Caetés, São Bernardo, Angústia, Vidas Secas and Infância. Thinking about the concepts of Antonio Candido on structure and function, we analyze how the literary construction relates to the social and historical life in the moment that the books were written, the decade of 1930. From the analyzes made, we realized the importance of these female characters, even when left in the background.

M.A. (Latin) / Please refer to full text to view abstract

Doctorat en philosophie et lettres / info:eu-repo/semantics/nonPublished

Les métastases osseuses sont des complications fréquentes du cancer du sein, responsables sur le plan clinique d'hypercalcémie, fractures osseuses et douleurs, pour lesquelles, il n'existe que des traitements palliatifs. Les cellules tumorales de carcinomes mammaires qui métastasent au site osseux expriment des gènes qui favorisent le tropisme osseux de ces cellules ainsi que leur ancrage et développement dans la moelle osseuse. Les mécanismes moléculaires sous-jacents à ces processus sont contrôlés par l'expression génique des cellules tumorales qui interagissent avec le microenvironnement et les cellules osseuses. Dans ce contexte, les microARNs en tant que régulateur endogène de l'expression génique, interfèrent avec les différentes étapes de la formation des métastases osseuses, incluant l'échappement des cellules tumorales de la tumeur primaire, la dissémination et l'invasion du site osseux, ainsi que l'apparition de lésions ostéolytiques. Les profils transcriptomiques des microARNs de cellules tumorales mammaires à caractère ostéotropique montrent que l'expression de la famille de microARNs-30s (miRs-30) est inhibée dans ces cellules. En clinique, la faible expression des miRs-30 est associée à un mauvais diagnostique de rechute et au statut hormono-résistant. Dans un modèle animal de métastases osseuses, l'expression forcée des miRs-30 dans des cellules tumorales qui métastasent fortement et spécifiquement à l'os, inhibe la formation des métastases osseuses. Nous montrons que les miRs-30 inhibent l'invasion et stimulent l'ostéoblastogenèse, in vitro et réduisent la charge tumorale et l'ostéoclastogenèse, in vivo. En accord avec ces résultats, l'expression de gènes qui stimulent les métastases osseuses est inhibée par les miRs-30. Parmi ces gènes, l'expression du CTGF (connective tissue growth factor) est augmentée dans les métastases osseuses humaines. Les étapes précoces des métastases osseuses sont étudiées par inoculation de cellules tumorales métastatiques murines dans la glande mammaire de souris. Dans ce modèle, les miRs-30 n'altèrent pas la croissance tumorale et la dissémination métastatique à l'os. Cependant, les miRs-30 inhibent l'invasion et le caractère de cellules souches tumorales de ces cellules métastatiques. Ces résultats suggèrent que les miRs-30, en régulant négativement les métastases osseuses, représentent une thérapie potentielle pour réprimer des gènes cibles qui stimulent les métastases osseuses / Bone metastasis is a common complication of advanced breast cancers and is clinically responsible of bone fractures, hypercalcemia and pain for which only palliative therapies are proposed. Breast tumor cells that preferentially invade bone express a set of deregulated genes that enhance bone tropism and facilitate bone marrow engraftment which may lead to the formation of overt osteolytic lesions. Molecular pathways underlining these steps are regulated through the tight control of genes expressed by cancer cells interacting with cells from the bone microenvironment. In this context, microRNAs act as regulators of gene expression and control multiple aspects of bone metastasis, including tumor cell escape from the primary site, dissemination, invasion of the bone marrow and secondary outgrowth. MicroRNA transcriptomic profiling of osteotropic breast cancer cell lines identified drastic down-regulation of the miR-30 family (miRs-30). In the clinic, low expression of miRs-30 in breast primary tumors is associated with poor distant metastasis-free survival and hormoneinsensitive status. In a model of human bone metastasis in vivo, the forced expression of miRs-30 in a breast cancer cell line that is highly and specifically metastatic to bone inhibited bone metastasis. We demonstrated that miRs-30 inhibit tumor cell invasiveness and stimulate osteoblastogenesis, in vitro, and reduces tumor burden and osteoclast activity, in vivo. Consistent with that, the expression of several genes that promote bone metastasis were inhibited by miRs- 30. Among these, expression of connective tissue growth factor (CTGF) was up-regulated in human bone metastasis. The early steps of bone metastasis were studied in a mouse model using spontaneously metastatic mouse breast cancer cell lines inoculated in the mammary gland. In this model, miRs-30 did not alter tumor growth or metastatic dissemination to bone. However, miRs-30 inhibited cell invasiveness and cancer stem cell-like phenotype of these metastatic cells. We conclude that miRs-30, by interfering negatively with bone metastasis, represent a potential therapy to repress gene targets that promote bone metastasis

In this thesis we have investigated the correlated ground state properties of polymers by applying wave-function-based ab-initio quantum-chemical methods such as the Hartree-Fock approach, the full configuration interaction method (FCI), coupled-cluster (CC) and Moller-Plesset second-order perturbation (MP2) theory. The polymers we have studied are the boron-nitrogen polymers, i.e., polyiminoborane (PIB) and polyaminoborane (PAB), the lithium hydride chain and the beryllium hydride polymer as well as the polymethineimine (PMI). The optimized structural parameters, cohesive energies, polymerization ernergies, relative stabilities of isomeric forms and some band structure results are presented. The results demonstrated that quantum chemical ab initio methods can be applied successfully to infinite systems like polymers, although such calculations are still far from being routine.