<p>Examensarbetet som beskrivs i denna rapport handlar om en ny teknik för att förbättra säkerheten för flygplan i luften och i närheten av flygplatser. Denna teknik benämns ADS-B (Automatic Dependent Surveillance Broadcast), och är tänkt att göra det möjligt för piloter att själva få information om trafik i närområdet. Nuvarande system baserar sig i huvudsak på visuella observationer från flygledare i kontrolltorn samt radarspaning omkring flygplatserna. Med det nuvarande systemet kommer det att bli både dyrt och svårt att upprätthålla en acceptabel nivå på flygsäkerheten när trafiken ökar. </p><p>Arbetet har bedrivits i AerotechTelubs regi i Linköping samt med hjälp ifrån företaget Sectra Wireless Technologies AB. Huvuddelen av arbetet inriktar sig på implementerandet av C-funktioner för att hantera kommunikationen och sammankopplandet av ett tidigare skapat system, för grafikvisning, med en transponder som hanterar ADS-B (tillverkad av Sectra). Målet med detta var att göra förberedande arbete åt AerotechTelub som de förhoppningsvis kommer att kunna använda i ett eventuellt kommande projekt. Rapporten tar upp några standarder som hör till konceptet GP&C (Global Positioning & Communication), samt beskriver de delar som ligger till grund för programmets funktion. </p><p>Examensarbetet har resulterat i ett demonstrationsprogram för att visa hur en lösning av problemet kan se ut. Det har tyvärr inte gått att säkerställa om programmet fungerar till fullo, men genom simuleringar och andra tester har huvuddelen av programmets funktioner gått att verifiera.</p>

ABA type tri-block amphiphilic polyelectrolyte consisting of poly(methyl methacrylate-block-methacrylic acid-block-methyl methacrylate) (P(MMA-b-MAA-b-MMA)) was synthesized by atom transfer radical polymerization technique (ATRP) and the self-assembly behavior of the polymers in aqueous solution was studied over the course of neutralization. Combination of potentiometric and conductometric titrations along with dynamic light scattering (DLS) techniques were used to investigate the size and shape of aggregates at various degrees of neutralization. The effect of hydrophobic-hydrophilic (MMA-MAA) ratio and polymer chain length on the aggregation behavior during neutralization was studied. P(MMA-b-MAA-b-MMA) with longer MMA segment self-assembles via the close association mechanism through stronger self-entanglement of MMA chains, whereas P(MMA-b-MAA-b-MMA) with shorter MMA chain self-assembles via the open association mechanism, as confirmed by transmission electron microscopy (TEM). Conductometric titration was used to determine the counterion condensation during the course of neutralization. When the charge density of micelle approaches a critical value as neutralization progresses, counterion condensation of Na+ ions on the polymer chains occurs. The effect of counterion condensation on the aggregation behavior during neutralization was elucidated. / Singapore-MIT Alliance (SMA)

Thesis (Ph.D.)--Memorial University of Newfoundland, 2005. / Bibliography: leaves 268-300.

No description available.

Introduktion: Hepatit B är ett virus med hög smittsamhet som är orsak till den vanligaste leversjukdomen globalt. I Vietnam är prevalensen av hepatit B hög.Syfte: Att undersöka vietnamesiska universitetsstudenters kunskap om hepatit B och attityder till hepatit B vaccination, samt att undersöka om det fanns någon skillnad mellan könen.Metod: En kvantitativ tvärsnittsstudie med hjälp av en enkät. Studien genomfördes på University of Medicine and Pharmacy i Ho Chi Minh City. Förstaårsstudenter på sjuksköterske- och medicinsk teknikprogrammet valdes ut och 233 studenter fyllde i enkäten korrekt och inkluderades i studien.Resultat: Majoriteten av studenterna (95,3%) hade hört om hepatit B viruset (HBV) innan studien ägde rum. Fler än hälften av studenterna (55,4%) visste att HBV inte sprids genom att dela mat med en infekterad person, och 58,4% visste att HBV kan orsaka levercancer. Endast 47,6% visste att HBV är sexuellt överförbart och 39,5% visste att HBV kan smitta från mor till barn perinatalt. Fler manliga studenter än kvinnliga visste att HBV kan överföras genom att dela tandborste med en infekterad person (p= 0,026). Majoriteten av studenterna (93,1%) trodde att de skulle vaccineras mot HBV i framtiden.Slutsats: Studenterna visade att de hade kunskap i ämnet, men studien visar också på en viss brist på kunskap, som är allvarlig. Förbättrad utbildning om HBV är nödvändigt för att vietnamesiska universitetsstudenter ska utöka sin kunskap om HBV. / Introduction: The hepatitis B virus is highly contagious and causes the world’s most common liver infection. Vietnam is a country where the endemicity of hepatitis B is high.Aim: To investigate Vietnamese university students’ knowledge about hepatitis B infection and attitudes towards hepatitis B virus vaccination and to examine if there is a difference between genders.Method: A cross-sectional study with quantitative method using a questionnaire. The study was carried out at the University of Medicine and Pharmacy in Ho Chi Minh City. First year students from the nursing and medical technician programme were selected and 233 students completed the questionnaire and were included in the study.Result: The majority of the university students (95.3%) had heard about hepatitis B virus (HBV). More than half (55.4%) knew correctly that HBV can not be transmitted by sharing food with an infected person, and 58.4% knew that HBV can cause liver cancer. Only 47.6% knew that HBV can be sexually transmitted and 39.5% knew that HBV can be transmitted from mother to child at birth. More male than female students answered correctly that HBV can be transmitted by sharing a toothbrush with an infected person (p= 0.026). Almost all students (93.1%) thought that they would receive HBV vaccination.Conclusion: The students showed insight into the subject, but the result also showed some gaps of knowledge among the university students considered as serious. Improved education about HBV is necessary for university students to increase their knowledge about HBV.

Siphonaria zelandica, a pulmonate mollusk, has been the subject of many natural product isolation studies by several, independent research groups. These studies have yielded several polypropionate structures (e.g. 4, 6, 8, and 10), which, upon careful inspection, were proposed to be related. There has been speculation that none of these isolated structures (4, 6, 8, and 10) are biosynthetic products, but are artifacts of isolation. Instead, it has been proposed that an unstable, acyclic precursor, such as 14/15 is the biosynthetic product produced by this mollusk; the putative acyclic precursor has not been isolated or synthesized. None of the synthetic studies on this series of compounds have attempted to address the potential relationships between these structures or speak to their status as natural products.<p> This work describes the enantioselective synthesis of the putative acyclic precursor 14/15 and its isomerization to siphonarin B (4). This was the first enantioselective synthesis of siphonarin B (4). Siphonarin B (4) was shown to readily undergo a retro-Claisen rearrangement to afford baconipyrone C (6) and concurrently undergo a retro-Claisen rearrangement/aldol cascade to provide baconipyrone A (6). This was the first total synthesis of baconipyrone A (6) through an unprecedented retro-Claisen rearrangement/aldol cascade and the first total synthesis of baconipyone C (8) by a biomimetic route versus the classical esterification route. The fourth compound in this series of potentially related compounds, caloundrin B (10), was never observed despite a careful search of each reaction crude where it may have been present.<p> The relationships between these compounds were probed and it was found, that under the conditions examined, the putative acyclic precursor 14/15 is not a biosynthetic product. Instead, siphonarin B (4) or perhaps caloundrin B (10), are the most likely biosynthetic products of the mollusk. Baconipyrone C (8) is not a precursor of baconipyrone A (6). The processes responsible for baconipyrones A (6) and C (8) are irreversible. As had been previously hypothesized, baconipyrones A (6) and C (8) are most likely artifacts of isolation (i.e., not natural products). The missing link in this series of compounds is caloundrin B (10) and its isomerization and rearrangement behavior.

Lepton pairs resulting from the decay of heavy flavor mesons are an important tool to probe the hot and dense matter created in nucleus-nucleus collisions at the Relativistic Heavy Ion Collider. Due to their large mass, heavy quarks are produced in the earliest stages of the collision and will, therefore, experience the full evolution of the system. The yield of heavy flavor mesons can be measured through their semi-leptonic decay channel by constructing like-sign and unlike-sign lepton pairs. Cross section measurements in p + p collisions provide a test of perturbative quantum chromodynamics (pQCD) theory in addition to a crucial baseline measurement to study the hot and cold nuclear matter effects present in heavy ion collisions. For the first time, the b¯b cross section in p+p collisions at √s = 500 GeV is measured. The results are based on the yield of high mass, like-sign dimuons measured in the PHENIX muon arm acceptance (1.2 < |y| < 2.2). The extrapolated total cross section is 25.2 ± 3.2 (stat) +11.4 -9.5 µb (sys). The cross section is comparable to pQCD calculation within uncertainties.

Siphonaria zelandica, a pulmonate mollusk, has been the subject of many natural product isolation studies by several, independent research groups. These studies have yielded several polypropionate structures (e.g. 4, 6, 8, and 10), which, upon careful inspection, were proposed to be related. There has been speculation that none of these isolated structures (4, 6, 8, and 10) are biosynthetic products, but are artifacts of isolation. Instead, it has been proposed that an unstable, acyclic precursor, such as 14/15 is the biosynthetic product produced by this mollusk; the putative acyclic precursor has not been isolated or synthesized. None of the synthetic studies on this series of compounds have attempted to address the potential relationships between these structures or speak to their status as natural products.<p> This work describes the enantioselective synthesis of the putative acyclic precursor 14/15 and its isomerization to siphonarin B (4). This was the first enantioselective synthesis of siphonarin B (4). Siphonarin B (4) was shown to readily undergo a retro-Claisen rearrangement to afford baconipyrone C (6) and concurrently undergo a retro-Claisen rearrangement/aldol cascade to provide baconipyrone A (6). This was the first total synthesis of baconipyrone A (6) through an unprecedented retro-Claisen rearrangement/aldol cascade and the first total synthesis of baconipyone C (8) by a biomimetic route versus the classical esterification route. The fourth compound in this series of potentially related compounds, caloundrin B (10), was never observed despite a careful search of each reaction crude where it may have been present.<p> The relationships between these compounds were probed and it was found, that under the conditions examined, the putative acyclic precursor 14/15 is not a biosynthetic product. Instead, siphonarin B (4) or perhaps caloundrin B (10), are the most likely biosynthetic products of the mollusk. Baconipyrone C (8) is not a precursor of baconipyrone A (6). The processes responsible for baconipyrones A (6) and C (8) are irreversible. As had been previously hypothesized, baconipyrones A (6) and C (8) are most likely artifacts of isolation (i.e., not natural products). The missing link in this series of compounds is caloundrin B (10) and its isomerization and rearrangement behavior.

Es gibt wenige Erkenntnisse über den Zusammenhang zwischen Lamivudin induzierten Resistenzmutationen und Hepatitis B Genotypen. Die vorliegende Studie untersucht das Verhältnis zwischen diesen Mutationen und den Hepatitis B Genotypen A-D. Die Datenbank der US-amerikanischen Kongressbibliothek (Pubmed) wurde nach den Begriffen „HBV OR hepatitis B”, „YMDD”, „genotype”, und „lamivudine” durchsucht. Alle in dieser Suche gefundenen Arbeiten, die bis Juni 2009 veröffentlicht worden waren, wurden in die Studie eingeschlossen. Die Ergebnisse der Literaturanalyse wurden mit den Hepatitis B-Genomdaten zweier Referenzlabore in Tübingen und Melbourne verglichen. Insgesamt konnten 29 Arbeiten aus der Datenbankrecherche in die Literaturanalyse eingeschlossen werden. Diese Studien enthielten Daten zu insgesamt 827 Patienten, deren Hepatitis B Genotyp bekannt war und die eine Lamivudinresistenzmutation aufwiesen. In statistischen Untersuchungen konnte nachgewiesen werden, dass die rtM204V-Mutation die dominierende Mutation bei Infektionen mit Genotyp A ist. Dieses Ergebnis konnte durch die Analyse der Genomdaten der Referenzlabore bestätigt werden. Ferner konnte gezeigt werden, dass bei den Genotypen A, B, und D die rtL180M-Mutation hochsignifikant mit der rtM204V-Mutation verknüpft ist. Die Dissertationsschrift enthält neben dem Artikel „Mutation pattern of lamivudine resistance in relation to hepatitis B genotypes: hepatitis B genotypes differ in their lamivudine resistance associated mutation pattern“ (Damerow, H, Yuen L et al.; J Med Virol. 2010 Nov; 82(11):1850-8) eine Einführung in die Rationale der Studie, eine Zusammenfassung der Ergebnisse sowie ein Fazit.

On top of cost reduction, product quality and manufacturing quality, manufacturing industry should start to consider the influence of business-to-business service quality on customers¡¦ satisfaction and loyalty. Therefore, how to measure customer perceived business-to-business service quality become a critical issue in manufacturing industry. Previously, the service quality research are more concentrated on business-to-consumer, such as retail or other service industry. However, it's not appropriate for apply it on business-to business level. The purpose of this paper is to study the influence of business-to business service quality on customer satisfaction and customer loyalty. This research is intended to prove the following. 1. IMP model is applicable to measure business-to-business service quality in manufacturing. 2. The better business-to-business service quality can lead to customer satisfaction and also customer loyalty. 3. To understand customer¡¦s satisfaction and loyalty on Manufacturing assembly and testing house in Taiwan accurately. This research attempts to find a relationship between six factors from IMP model and business-to-business service quality. Further, to know if business-to-business service quality can affect customer satisfaction and customer loyalty, especially more purchasing behavior.The research methodology is to use Woo & Ennew¡¦s (2005) questionnaires which based on the concept of IMP model. We provided questionnaires to Taiwan¡¦s assembly and testing house¡¦s customers. There are 143 returned with effective results. The conclusion of the research showed the business-to-business service qualtiy have significant and positive effects on customers satisfaction then to loyalty. However, the questionnaires didn¡¦t have a good fit to measure business-to-business service quality in manufacturing. From the result, it remind manufacturer take business-to-business sevrice quality seriously and pay much attention to it.