Made available in DSpace on 2016-04-27T19:31:31Z (GMT). No. of bitstreams: 1 Paulo Costa.pdf: 19161926 bytes, checksum: 86cd40cb849a781cfa5922a4715c8722 (MD5) Previous issue date: 2007-05-17 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Beginning with the naming of the first governor of the Federal Territory of Amapá in 1943, Captain Janary Gentil Nunes, the local style of life was systematically disrespected by that government and by the succeeding governments during the period between 1945 and 1970, stamped by an idea of progress for the region based on a network of highways despite the existing waterways by means of its rivers the dominant facet of life in the region. Such political disdain generated tension between the officially adopted political speech - prioritizing and expanding road construction and the lifestyle of the Amapaenses whose experience and survival were drawn from the rivers. It is within this context that this Master's Dissertation presents a study about the river-water lifestyle and the regatões, the commercializing boat culture that supplied varied goods to the city of Macapá, capital of the Territory. It will demonstrate as well that the rivers were fundamental for the regatões, not only affecting the trading and commercial business, but also in relation to the living experience which transformed itself into the essence of the people of the region. In the study of this specific lifestyle - the regatões, the use of oral documentation in the form of interviews with people directly involved provides evidence of the problematizing of life style of those who anchored their canoes at the Doca do Canal do Igarapé da Fortaleza de São José de Macapá, in opposition to the intention of the territorial governors of building land-based roads. In this manner, a comprehension of the lifestyle of various of the regatão people was undertaken not out of a nostalgic sense of a lost time, but as a means of identifying the tensions and extant contradictions between the governmentally adopted discourse and the ways of life that were occurring facing the changes in the Territory of Amapá at that time / A partir da nomeação do primeiro governador do Território Federal do Amapá, Capitão Janary Gentil Nunes, em 1943, o modo de vida local foi sistematicamente desconsiderado por seu governo e pelos governantes que o sucederam no período compreendido entre 1945 e 1970, balizado pela idéia de progresso para a região baseada na construção de uma malha rodoviária em desprezo às hidrovias existentes a grande marca da vida regional através de seus rios. Tal desdém político gerou tensão entre o discurso oficial adotado que priorizava e engrandecia a construção de estradas contra o modo de vida local dos amapaenses que retiravam dos rios sua vivência e sobrevivência. Diante deste contexto, esta Dissertação de Mestrado apresenta um estudo sobre o modo de vida marítimo-fluvial e a cultura material dos regatões que comercializavam e abasteciam com gêneros variados a cidade de Macapá capital do então Território. Demonstra, outrossim, que para os regatões os rios eram fundamentais não apenas no tocante às trocas e negociações comerciais, mas também em relação às experiências vividas que se traduzem na essência dos homens da região. No estudo de um modo de vida específico o dos regatões, a utilização de documentação oral foi evidenciada através da problematização do modo de vida dos sujeitos que fundeavam suas canoas na Doca do Canal do Igarapé da Fortaleza de São José de Macapá, em oposição à intenção dos governantes territoriais em construir estradas de rodagem. Desta forma, o entendimento do modo de vida de alguns regatões foi desenvolvido não com um sentido nostálgico e perdido no tempo, mas como uma forma de identificação da tensão e da contradição existente entre o discurso governamental adotado e as formas de viver que ocorriam frente às mudanças que aconteciam no Território do Amapá naquele momento

A proteína jun é um dos principais integrantes do complexo AP-1 e está envolvido nos processos inflamatórios, diferenciação, apoptose e migração celular. Esta proteína pode formar homodímeros e heterodímeros por meio da dimerização que ocorre pelo sítio de sequências de leucinas. Existem evidências de que a proteína jun pode ser inibida pela proteína RPL10 mediante a ligação destas proteínas, no mesmo sítio de sequências de leucinas no núcleo celular, parando a progressão de tumores. O objetivo deste trabalho foi expressar, isolar e caracterizar a região de ligação das sequências de leucinas (região AP-1), para estudos posteriores de ligação com a proteína RPL10. O cDNA para proteína jun foi amplificado por PCR e clonado nos vetores de expressão pET 26b(+), pET 28a-c(+) e p1813 e expressa em E.coli BL21 (DE3). A proteína expressa em vetor pET28_AP1 foi eficientemente purificada pela técnica de cromatografia de afinidade a íons metálicos, por possuir uma sequência (poli)histidina que facilitou a purificação, apresentando um excelente grau de pureza. A identidade da proteína foi confirmada através de análise feita por western blotting e dot blotting e também por analise por espectrometria de massas. / The jun protein is one of the main AP-1 complex members and is involved in the inflammatory process, differentiation, apoptosis and cell migration. The Jun protein may form homodimers and heterodimers by dimerization in the leucines sequences site. There are evidences that jun protein can be inhibited by RPL10 protein through these protein binding in the same leucine sequences site, in the cell nucleus, stopping the tumor progress. The objective of this study was to express, isolate and characterize the binding region of the leucine sequences (AP-1 region) for subsequent binding studies with RPL10 protein. The jun protein cDNA was amplified by PCR and cloned into pET 26b(+), pET 28a-c(+) and p1813 expression vectors, and was expressed in E.coli BL21 (DE3). The protein expressed in pET28_AP1 vector was efficiently purified by the affinity chromatography technique to metal ions because have a (poly)histidine sequence which facilitate the protein purification, showing an excellent high purity. The protein identity was confirmed by western blotting and dot blotting and also by mass spectrometry analysis.

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2016-08-23T17:05:27Z No. of bitstreams: 1 2011 - Michele Valadares Deveza.pdf: 2385296 bytes, checksum: 127bd8c33d0595f06af98fe22cfc21e1 (MD5) / Made available in DSpace on 2016-08-23T17:05:27Z (GMT). No. of bitstreams: 1 2011 - Michele Valadares Deveza.pdf: 2385296 bytes, checksum: 127bd8c33d0595f06af98fe22cfc21e1 (MD5) Previous issue date: 2011-02-08 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The bee?s pollen is a product rich in essential nutrients to feed the bees. In the hive it goes through chemical processes and becomes the bee?s bread, of extreme importance for the growth of larvae. Currently, the use of pollen in the human?s cuisine has been increasing for its therapeutic properties, and by its use in the food industry. To produce quality pollen the hive needs to be healthy, and bees, like any other animal, are susceptible to various diseases, parasites and predators, which can affect their development and productivity. The The Brazilian Sac Brood (BSB) is one of these diseases, which in Brazil affects honeybee larvae. In apiaries of Rio de Janeiro state, a high mortality of larvae with symptoms similar to the BSB is occurring, and until now, there is no definite conclusion regarding the etiologic agent of this disease in the state. Therefore, the objectives of this study was to clarify two issues: 1) provide a mycological research, through a study case, of bees? bread samples, adult bees and bees? pollen in areas affected and not affected by the BSB, aiming the elucidation of its etiologic agent, 2) verify the hygienic quality of dehydrated pollen samples sold in Rio de Janeiro state. A total of 48 samples of bees? bread, 15 of adult bees and 12 of pollen were collected from endemic regions of the BSB. The samples were collected in the months before, during and after the period of the disease. The dehydrated pollen samples were also purchased in commercial stores of the state, totaling 27 samples. Fungal species enumeration (cfu g-1) was through decimal dilution method using general culture media and selective ones. The isolation frequency and relative density of species were determined. The toxigenic profile of strains was determined, as also the detection and quantification of aflatoxin B1 in bread and bees? pollen. The results obtained from the study case samples showed that the bees? bread was the best vehicle of contamination for the hive. It was also observed a high fungal counts and the presence of mycotoxins and entomopathogenic fungi such as Aspergillus flavus, A. niger aggregate and A. fumigatus, which cause a decrease of the immune response, leaving them susceptible to various diseases, including the BSB itself. Pollen dehydrated samples showed a high fungal contamination with 92% of the samples in unsatisfactory hygienic conditions according to legal standards. A total of 25% of the A. flavus strains showed to be aflatoxigenic. The high percentage of unhygienic samples combined with the presence of a large variety of fungal contaminants, including mycotoxin-producing species, evidences that the legislation needs to be updated so that it can be safely commercialized. It is considered that the whole line production of bees? pollen, since its extraction until its storage should be monitored in order to minimize risks to human health. / O p?len ? um produto ap?cola rico em nutrientes essenciais para a alimenta??o das abelhas. Na colmeia ele passa por processos qu?micos e se torna o p?o de abelhas, de extrema import?ncia para o crescimento das larvas. Atualmente, o p?len ap?cola vem se destacando tamb?m na alimenta??o humana, tanto por suas propriedades terap?uticas, quanto pela sua utiliza??o na ind?stria aliment?cia. Para a produ??o de um p?len de qualidade a colmeia precisa estar sadia, e as abelhas, como qualquer outro animal, s?o suscept?veis a v?rias doen?as, parasitas e predadores, que podem prejudicar seu desenvolvimento e produtividade. A Cria Ensacada Brasileira (CEB) ? uma dessas doen?as, que no Brasil acomete larvas de abelhas mel?feras. Em api?rios do estado do Rio de Janeiro v?m ocorrendo uma alta mortalidade de larvas com sintomatologia semelhante a da CEB, e ainda n?o h? uma conclus?o definitiva acerca do agente etiol?gico desta doen?a no estado. Portanto, os objetivos desse estudo visam esclarecer duas problem?ticas: 1) avaliar, atrav?s de estudo de caso, amostras de p?o de abelhas, abelhas adultas e p?len ap?cola em regi?es atingidas e n?o atingidas pela CEB, diagnosticando a presen?a de fungos, visando fornecer informa??es importantes para a elucida??o do agente etiol?gico da CEB no estado do Rio de Janeiro; 2) verificar a qualidade higi?nica das amostras de p?len desidratado comercializado no estado do Rio de Janeiro. Um total de 48 amostras de p?o de abelhas, 15 de abelhas adultas e 12 de p?len ap?cola, foram adquiridas de regi?es end?micas da CEB. As coletas ocorreram nos meses que antecederam, durante e ap?s o per?odo da doen?a. J? as amostras de p?len desidratado foram adquiridas no com?rcio do estado, totalizando 27 amostras. A enumera??o da micobiota (ufc g-1) foi realizada atrav?s do m?todo de dilui??o decimal com semeadura em placas utilizando-se meios de cultivo gerais e seletivos. Foram determinadas a freq??ncia de isolamento dos g?neros f?ngicos e a densidade relativa das esp?cies. Foi determinado o perfil tox?geno de cepas isoladas e foi feita a detec??o e quantifica??o de aflatoxina B1 no p?o de abelhas e p?len ap?cola. Nos resultados obtidos das amostras do estudo de caso, o p?o de abelhas mostrou ser o melhor substrato para o ve?culo de contamina??o para a colmeia. Observou-se tamb?m altas contagens f?ngicas, al?m da presen?a de micotoxinas e fungos entomopatog?nicos, como Aspergillus flavus, A. niger agregados e A. fumigatus o que favorece a queda da imunidade desses insetos deixando-os suscet?veis a diversas doen?as, entre elas a pr?pria CEB. Em rela??o ao p?len desidratado, os resultados mostraram uma alta carga f?ngica com 92% das amostras em condi??es higi?nicas insatisfat?rias segundo os padr?es legais consultados e 25% das cepas de A. flavus mostraram-se potencialmente produtoras de aflatoxinas. Os alt?ssimos percentuais de reprova??o das amostras para a qualidade higi?nica, aliado ? presen?a de grande variedade de fungos contaminantes, incluindo esp?cies produtoras de micotoxinas, ? uma evid?ncia de que a legisla??o necessita ser atualizada, para que este produto possa ser comercializado com seguran?a. Considera-se que toda a linha de produ??o do p?len ap?cola, desde sua coleta at? o armazenamento deva ser monitorada, a fim de minimizar os riscos para a sa?de humana

Orientador: Tania Maria Alkmim / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem / Made available in DSpace on 2018-08-06T09:38:18Z (GMT). No. of bitstreams: 1 Oliveira_EdnadosSantos_M.pdf: 8039496 bytes, checksum: b74f46e793c4682414efb52b400338c4 (MD5) Previous issue date: 2006 / Resumo: O objeto de estudo desta dissertação é a comunidade afro-descendente de Curiaú, especificamente os aspectos lingüísticos em correlação com os aspectos sociais, uma vez que se trata de pesquisa sociolingüística. A partir da leitura cuidadosa da escritura curiauense e da observação das atividades cotidianas e festivas de Curiaú, identificamos uma mudança no seu comportamento lingüístico que se traduz na escrita pelas mãos da comunidade da sua própria história, sobretudo uma nova história. Isso nos permitiu postular que a introdução de uma outra forma de comunicação tem motivação social, mais especificamente, está associada ao reconhecimento da sua remanescência quilombola, evidenciada através da temática abordada nos livros, no jornal, assim como nos poemas. Identificamos que a escritura está para além da fixação da história que, naturalmente, a escrita promove. Há um outro aspecto embutido nessa escritura, isto é, ela tem uma evidente função social que é a sustentação da vida quilombola. Somente através da observação de aspectos relativos às mudanças de natureza social e política e a associação com o fenômeno lingüístico é que pudemos identificar essa relação. Estamos tratando ainda esse processo de escrita como a inserção de uma nova tradição, uma vez que as práticas dessa comunidade giravam em torno da oralidade. Assim, o advento da escrita representa uma nova tradição, sobretudo em atividades que só se realizavam oralmente / Abstract: The object of study of this dissertation is the afro-descending community of Curiaú, specifically the linguistic aspects in correlation with the social aspects, once it is a research on sociolinguistics. Starting from the careful reading of the writing curiauense and of the observation of the daily and festival activities of Curiaú, we identified a change in its linguistic behavior that translates itself in the writing by the hands of community's own history, especially a new history. This allowed us to postulate that the introduction of another way of communication has social motivation, more specifically, it is associated with the recognition of its remanescência quilombola, evidenced through the theme approached in the books, in the newspaper, as well as in the poems. We identified that the writing is beyond the fixation of the history that, naturally, the writing promotes. There is another aspect embedded in that writing, that is, it has an evident social function that it is the sustentation of the life quilombola. Only through the observation of aspects related to the changes of social and political nature and the association with the linguistic phenomenon we could identify that relationship. We are still treating that writing process as the insert of a new tradition, once that community's practices rotated around the orality. This way, the coming of the writing represents a new tradition, above all in activities that only took place orally / Mestrado / Sociolinguistica / Mestre em Linguística

Les cancers du sein triple négatifs (TNBC) ne bénéficient d’aucune thérapie ciblée et restent incurables. L’identification de nouvelles cibles moléculaires diagnostiques et surtout, thérapeutiques constitue donc un enjeu majeur pour le traitement de ces cancers. Fra-1 et Fra-2, deux constituants du complexe transcriptionnel AP-1, sont surexprimés dans les TNBC où ils participent à l’agressivité tumorale et/ou la métastatisation. Les gènes cibles de Fra-1 et Fra-2, ainsi que les mécanismes moléculaires via lesquels ils gouvernent la transcription de leurs gènes cibles sont très peu caractérisés. Dans ce contexte, l’objectif général de ma thèse à été d’identifier les gènes codants sous contrôle de Fra-1 et/ou Fra-2 et de caractériser les sites de fixation de Fra-1 et Fra-2 sur la chromatine pour identifier des cibles directes, en combinant des approches transcriptomiques et génomiques combinées à l’interférence à l’ARN dans la lignée modèle MDA-MB231. Les résultats obtenus, associés à l’analyse de banques de données humaines, ont permis la sélection de gènes cibles pour les études mécanistiques et fonctionnelles. Le gène HMGA1, choisi en raison de son rôle maintenant bien établi dans l’agressivité des tumeurs épithéliales, a fait l’objet d’une étude portant sur les mécanismes transcriptionnels gouvernés par Fra-1 et/ou Fra-2 pour sa régulation. L’étude fonctionnelle a été focalisée sur CD68 dont l’expression est fortement induite par Fra-1 et Fra-2. CD68 code pour une protéine transmembranaire dont la fonction n’est pas clairement établie et dont l’implication dans le phénotype tumoral n’a jamais été étudiée. / Triple negative breast cancers (TNBC) are characterized by a poor prognosis and no targeted therapy is currently available. The identification of new diagnostic and therapeutic targets is crucial for the treatment of these cancers. Fra-1 and Fra-2, two members of the AP-1 transcriptional complex, are frequently overexpressed in TNBC, where they contribute to the tumorigenic phenotype. The panel of genes under the control of Fra-1 and/or Fra-2 in TNBC, as well as the molecular mechanisms by which they control their target gene expression are mostly unknown. The aim of my thesis was to identify the panel of genes controlled by Fra-1 and/or Fra-2 in TNBC and to characterize the binding sites of Fra-1 and Fra-2 on chromatin to select direct targets for further studies, by using transcriptomic and ChIP-seq approaches combined to RNAi in the model cell line MDA-MB231. The results allowed us to select target genes for transcriptional and functional studies. The study of the transcriptional mechanisms governed by Fra-1 and/or Fra-2 was carried out on the HMGA1 gene, already known for its crucial role in the aggressiveness of epithelial tumours. The fonctional study was focused on CD68, as its expression in highly induced by Fra-1 and Fra-2. CD68 encodes a transmembrane protein which cellular fonction is still not known and its potential role in tumorigenesis has not been studied yet.

Orientador: Paulo Celso Miceli / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciencias Humanas / Made available in DSpace on 2018-07-31T22:44:33Z (GMT). No. of bitstreams: 1 Campos_NezildaJaciraLourinhode_M.pdf: 12225967 bytes, checksum: 6b9b192555b854b78dec71b491cae155 (MD5) Previous issue date: 2002 / Resumo: Esta dissertação apresenta um estudo realizado em Macapá, capital do Estado do Amapá, sobre uma comunidade de negros denominada Vila do Curiaú, cuja atração maior está no fato de ter sido reconhecida e tombada pela Fundação Palmares como terra remanescente de quilombo. Objetivando resgatar parte do acervo histórico e sócio - cultural daquele universo, foi iniciada em 1996 uma pesquisa de campo com sete velhos filhos daquela comunidade, que, através de depoimentos auto - biográficos, fi-uto das memórias, caracterizaram a realidade cotidiana do passado e do presente, sinalizando também perspectivas de futuro para a comunidade que até hoje e a muito custo, ainda resiste às interferências externas de um modelo etnocêntrico padronizado e ostentado como mais viável para todos os povos e" raças". Através da história oral e história de vida dos negros velhos do Curiaú, este estudo apresenta parte de seu universo material e simbólico, pois os relatos caracterizaram especificidades sobre mentalidade, costumes e crenças de uma comunidade negra, localizada num espaço geográfico ímpar e agraciado pela natureza, que lhe presenteou com solo fértil e um lago majestoso não só pela beleza, mas principalmente pela utilidade que tem para a criação de gado e pela variedade de peixes que lá existem, utilizados apenas para subsistência dos moradores e filhos da terra. Os depoimentos resgatam e aqui registram a origem da Vila com todas suas controvérsias, seus primeiros habitantes, as características antigas do lugar e das habitações, formas de trabalho, cultura, relações sociais e de parentesco; além da crença religiosa manifestada através da fé católica dirigida principalmente a São Joaquim, santo padroeiro do lugar e merecedor de festejo mesclado de relações sagradas e profanas durante nove dias. Este estudo também discute, embora não especificamente, o papel do poder público nas relações com o lugar e seus habitantes que, desanimados, percebem a aproximação da perda de suas raízes, hábitos e costumes, por falta de uma política de conscientização, valorização, resgate e preservação do lugar, principalmente junto às gerações maisjovens que se sentem mais atraídas e mais próximas dos costumes colonizadores e "civilizados" do branco, nos tempos modernos de tecnologia consumista / Abstract: This dissertation presents a study carried out in the city of Macapá, State of Amapá, Brazil that deals with an Afro-Brazilian community--- Vila do Curiaú. This community has been officially recognized by the Palmares Foundation as a parcel of land which was originally a "quilombo". With the intention of preserving part of the important historical and socio-cultural heritage of this community, seven elderly residents were interviewed in order to document their memory ofthe past, views of the present and perspectives for the future.This research is important for it indicates that the community still attempts to resist external interference based on a ethnocentric and stylized model, held up as the sole model for all peoples and races. By means of an oral history narrated by the elderly residents themselves, this study presents part of their material and symbolic universe. Their narratives point to the way of thinking, customs, beliefs and view of the world of an Afro-Brazilian community situated in a privileged geographical space, blessed by nature, which provides the residents with fertile soil as well as a majestic lake enabling them to fish for their subsistence and bring their cattle to water. The interviews register the origin of the Vila with all its controversies, its first inhabitants, the characteristics of the place in times past with its dwellings, work activities, culture, social relations and kinship as well its religious belief directed centered mainly on Saint Joachim, patron saint of the locale. The interviewees in their narratives point to the nine-day long festival in honor of that Saint in which the sacred and the profane intermingle. This study also refers in part to the role of the governrnent in its dealings with the community and its residents who sadly relate their own perception of the approaching demise of their roots, habits and customs due to the lack of a policy of consciousness raising with regard to the protection of the cultural and historical heritage of the place, in particular with the younger generations who appear to be closer to and more attracted by the colonizing customs and supposedly "civilized" of present-day white culture with its consumer technology and drive toward modernization / Mestrado / Mestre em História

<p>Lens development is an intricate process governed by growth factor signaling and a hierarchy of transcription factors that regulate important processes required for normal lens development.</p> <p>Midline hedgehog (Hh) signaling has been implicated in lens defects including cyclopia and lens degeneration in rodents and fish. A lens specific model of hedgehog signaling has not been examined, and it was unknown whether the lens is able to respond to Hh signals. To investigate this question, and to determine any consequences of abnormal Hh signaling on lens development, a mouse model of constitutively active smoothened in the surface ectoderm and derivatives, (including the lens), was created. These mutants exhibited ectopic expression of FoxE3 by E12.5, and ectopic Pax6 expression by E15.5, along with deregulation of the lens cell cycle and lens degeneration.</p> <p>Similar to the Hh signaling pathway, normal expression of the transcription factor Activating Protein-2 (AP-2, <em>tcfap2</em>), in the lens, was shown to be essential for the maintenance of an epithelial cell phenotype, and the regulation of the lens cell cycle. AP-2α has been shown to be important at the placode stage of development for correct separation of the lens vesicle away from the overlying surface ectoderm. Defects resulting from the loss of AP-2α at this stage do not manifest until E12.5, at time at which AP-2β expression is lost in the lens, suggesting possible redundancy between the two AP-2 family members in early lens development.</p> <p>To investigate this possible redundancy, <em>Tcfap2a </em>and <em>Tcfap2b</em> were conditionally deleted from the lens at E9.5 (AP-2α/β DKOs). These family members were shown to play redundant roles during early lens development, with the double mutants exhibiting more severe defects than those seen in the AP-2α single knockout model A more nasally positioned lens stalk and a rotated lens were observed. Severe corneal defects and deregulation of the lens cell cycle were also evident.</p> <p>Roles for AP-2α in later lens development were unknown. To examine whether or not this transcription factor continues to play a role in lens epithelial cell maintenance subsequent to lens vesicle separation, a mouse model with <em>Tcfap2a</em> conditionally deleted from the lens during these later stages of development was created (MRL10-AP-2α). These mutants displayed a disorganized and multilayered lens epithelial cell layer with elongated epithelial cells that abnormally expressed fiber cell specific β/γ crystallins. These mutants also exhibited defects in cell adhesion between the epithelium and fiber cells, as well as between the epithelium and capsule, and exhibited fiber cell defects including vacuoles.</p> <p>Together, the work presented in this thesis outline previously unknown roles for Hh and AP-2 signaling in lens development. Both Hh and AP-2 are required for the maintenance of a normal lens epithelial cell phenotype and regulation of the cell cycle. This thesis also illustrates the requirement (and redundant roles) for AP-2α and AP-2β at the lens placode stage of development.</p> / Doctor of Philosophy (Medical Science)

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Submitted by Larissa Silva (larissasilva@ufpa.br) on 2018-04-13T19:35:54Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_PraticaMusicalVomineFestaSaoTiago.pdf: 7054435 bytes, checksum: e16aee94434d6e66e79173f7012d989e (MD5) / Approved for entry into archive by Larissa Silva (larissasilva@ufpa.br) on 2018-04-17T13:26:33Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_PraticaMusicalVomineFestaSaoTiago.pdf: 7054435 bytes, checksum: e16aee94434d6e66e79173f7012d989e (MD5) / Made available in DSpace on 2018-04-17T13:26:33Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_PraticaMusicalVomineFestaSaoTiago.pdf: 7054435 bytes, checksum: e16aee94434d6e66e79173f7012d989e (MD5) Previous issue date: 2017-07-29 / CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Esta pesquisa problematiza aspectos da prática musical chamada Vominê que integra a Festa de São Tiago, em Mazagão Velho – AP. A festividade dedicada a São Tiago é uma prática secular que acontece anualmente, sendo o Vominê, espécie de celebração da vitória ou exaltação à bravura, parte integrante do festejo. Investigar a prática musical do Vominê, considerando a maneira como esta opera em suas estruturas tanto musicais quanto sociais em seu contexto foi o nosso objetivo principal. Tendo como suporte as perspectivas teóricas da etnomusicologia, discutimos sobre as potencialidades representativas dessa prática musical em relação aos indivíduos que dela tomam parte, considerando a revisão da literatura consultada, a observação direta da realidade, e a análise cultural da prática musical como proposta por Chada, Blacking, Seeger e Geertz. / The present work problematizes aspects of the musical practice called Vominê, that integrates the Festa de São Tiago in Mazagão Velho, lacated in Amapá province. Supported by the theoretical perspectives of ethnomusicology, it is sought to reflect on the potentialities representative of this practice in relation to the individuals that take part of it. The Festivity of St. Tiago is a secular practice that happens annually, with Vominê, a kind of song of victory or exaltation of bravery, an integral part of this festivity. Investigating Vominê's practice, considering the way it operates in its musicais and social structures in its context is our main objective. In order to do so, we started with a review of the available literature and the direct observation of reality, considering the cultural analysis of the musical practice as proposed by Chada.

Next Generation networks (3G and beyond) are evolving towards all IP based systems with the aim to provide global coverage. For Mobility in IP based networks, Mobile IPv6 is considered as a standard by both industry and research community, but this mobility protocol has some reliability issues. There are a number of elements that can interrupt the communication between Mobile Node (MN) and Corresponding Node (CN), however the scope of this research is limited to the following issues only: • Reliability of Mobility Protocol • Home Agent Management • Handovers • Path failures between MN and CN First entity that can disrupt Mobile IPv6 based communication is the Mobility Anchor point itself, i.e. Home Agent. Reliability of Home Agent is addressed first because if this mobility agent is not reliable there would be no reliability of mobile communication. Next scenario where mobile communication can get disrupted is created by MN itself and it is due to its mobility. When a MN moves around, at some point it will be out of range of its active base station and at the same time it may enter the coverage area of another base station. In such a situation, the MN should perform a handover, which is a very slow process. This handover delay is reduced by introducing a “make before break” style handover in IP network. Another situation in which the Mobile IPv6 based communication can fail is when there is a path failure between MN and CN. This situation can be addressed by utilizing multiple interfaces of MN at the same time. One such protocol which can utilize multiple interfaces is SHIM6 but it was not designed to work on mobile node. It was designed for core networks but after some modification in the protocol , it can be deployed on mobile nodes. In this thesis, these issues related to reliability of IPv6 based mobile communication have been addressed.