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The Global ETD Search service is a free service for researchers
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Showing 1 to 2 of 2 (0.034 seconds)Spelling suggestions: "subject:"arvsmassa"" "subject:"arvsmassan""
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Jämförelse av spermakvalitet med avseende på DNA fragmentations index (DFI) : Hos svenska och danska män med fertilitetsproblematik / Comparison of sperm quality with regards to DNA fragmentation index (DFI) : In Swedish and Danish men with fertility problemsBjörk, Matilda January 2024 (has links)
För att bedöma mäns spermiekvalitet och därmed pars chanser till en graviditet har standardparametrar tidigare använts som fertilitetsindikator, men har visat sig vara en mindre tillförlitlig metod. Därför har en ny metod som bygger på flödescytometri och kallas Sperm Chromatin Structure Assay (SCSA) utvecklats som fokuserar på spermiernas arvsmassa, och som då har visat sig vara en mycket mer tillförlitlig metod. Syftet med denna studie var att jämföra DNA Fragmentations Index (DFI) -värde mellan svenska och danska män och se om en signifikant skillnad finns. För att uppfylla detta späddes och färgades spermaproven in och analyserades med SCSA, som därefter gav hur stor andel av spermiernas DNA som är defekt, vilket presenterades som ett procentuellt DFI-värde. Resultatet visade en signifikant skillnad av medianvärdet mellan svenska och danska män med avseende på DFI, där svenska män hade högre medianvärde än de danska männen. Detta i kombination med tidigare forskning som gjordes mellan svenska och danska män och som visade att svenska män hade bättre kvalitet än danska män med avseende på standardparametrarna, stödjer tidigare forskning som visar på att det ej finns ett samband mellan standardparametrar och DFI. Dock hade ytterligare forskning av skillnaderna mellan svenska och danska män behövts, för att validera fynden i denna studie. / To assess men's sperm quality and thus couples' chances of pregnancy, standard parameters have previously been used as a fertility indicator, but have proven to be a less reliable method. Therefore, a new method based on flow cytometry called Sperm Chromatin Structure Assay (SCSA) has been developed which focuses on the sperm's genetic mass, and which has been shown to be a much more reliable method. The purpose of this study was to compare the DNA Fragmentation Index (DFI) value between Swedish and Danish men and see if a significant difference exists. To fulfill this, the sperm samples were diluted and stained and analyzed with SCSA, which then gave the ratio of the sperm's DNA that is defective, which was presented as a percentage DFI value. The result showed a significant difference in the median value between Swedish and Danish men with regard to DFI, where Swedish men had a higher median value than the Danish men. This, in combination with previous research that has been done between Swedish and Danish men which showed that Swedish men had better quality than Danish men in regards to the standard parameters, supports previous research that shows that there is no connection between standard parameters and DFI. However, further research into the differences between Swedish and Danish men is needed to validate the findings in this study.
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Gemensamma Symboliska Beteenden Och Interaktioner Mellan Neanderthalare Och H. SapiensKarlsson, Julia January 2022 (has links)
The behaviours that the Neanderthals and Homo sapiens sapiens had in common could have made their interaction more advanced and deeper. Ever since Richard E. Green et al’s discovery in 2010 that a lot of the modern day population have inherited about 1-4 % of the genome from Neanderthals, the assumption that Neanderthals are primitive beings lacking advanced cognition has changed. For H. Sapiens to interbreed with Neanderthals one could argue that they could not have been that dissimilar. Since the modern day population inherited parts of the Neanderthals it could be very interesting to bring more insight into how their relationship and interaction would have looked in relation to H. Sapiens. In this thesis some behaviours will be analysed and compared that existed among them both. In this remark it will be about behaviors of a symbolic nature, indicating a more advanced thinking. These are the usage of personal ornaments, the burial practice, and lastly language and speech. The personal ornaments they used are in some instances very similar, but there is also variation in what they put value in as personal ornaments, later H. Sapiens put a lot of energy into making beads of different types, and Neanderthals having a focus on birds of prey. The burial practice is in general nothing that is too common among either of them during the middle palaeolithic or African Middle stone age. Before the upper palaeolithic there is not too much evidence indicating that they had a tradition of burying their dead. In cases they did bury their dead there is evidence of places with multiple burials, maybe working as grave centers. The anatomical capacities for speech existed among them both. When it comes to language it is harder to discern, since it does not fossilise, but since language is symbolic it could be argued that evidence of symbolism among them could indicate that they had language as well. In the discussion and conclusions it is argued that these common behaviours could have made it possible for a more advanced interaction and relationship between the two.
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