Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-04T12:43:24Z No. of bitstreams: 2 fabricio_paula.pdf: 833499 bytes, checksum: 4864104f710a7129c6089e9dac7beda1 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-04T12:43:53Z (GMT) No. of bitstreams: 2 fabricio_paula.pdf: 833499 bytes, checksum: 4864104f710a7129c6089e9dac7beda1 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2016-01-04T12:43:53Z (GMT). No. of bitstreams: 2 fabricio_paula.pdf: 833499 bytes, checksum: 4864104f710a7129c6089e9dac7beda1 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2012 / Atletas de v?rias modalidades desportivas realizam mais de uma sess?o de treinamento por dia. Diversas estrat?gias t?m sido utilizadas com o intuito de acelerar a recupera??o p?s-exerc?cio. Embora a imers?o em ?gua seja uma estrat?gia comum entre os atletas, a sua efic?cia na acelera??o da recupera??o ainda n?o est? estabelecida, e os efeitos da temperatura da ?gua na imers?o sobre o desempenho n?o s?o claros. Sendo assim, este estudo avaliou os efeitos da recupera??o passiva por imers?o em ?gua, em diferentes temperaturas, sobre o desempenho ap?s uma sess?o de exerc?cio. Nove homens, jovens, fisicamente ativos, participaram de quatro sess?es experimentais randomizadas compostas por exerc?cio exc?ntrico (3 x 10 repeti??es a 100% de uma repeti??o m?xima) e 90 minutos de corrida em esteira rolante a 70%do pico de consumo de oxig?nio. Em seguida, os volunt?rios recuperaram durante 45 minutos, distribu?dos em 15 minutos de imers?o em ?gua a 15, 28 ou 38?C sentados e 30 minutos deitados em repouso a temperatura ambiente (20 ? 2? C). Na sess?o controle (CON), durante a recupera??o, os volunt?rios permaneceram sentados durante 15 minutos ? temperatura ambiente. Quatro horas ap?s o final do exerc?cio experimental, os volunt?rios foram submetidos ? corrida de intensidade autorregulada m?xima de 5 km seguido do teste de Wingate para avaliar o desempenho f?sico. A temperatura retal (Tret), a frequ?ncia card?aca (FC) e sua variabilidade (VFC) foram medidas ao longo de toda a sess?o. O consumo excessivo de oxig?nio p?s-exerc?cio (EPOC) foi medido durante a recupera??o. Os marcadores do dano muscular, creatina quinase (CK) e aspartato amino transferase (AST) e a contagem de leuc?citos totais foram medidas antes e ap?s o exerc?cio, ap?s imers?o, antes e ap?s o desempenho, e 24 horas ap?s o exerc?cio experimental. A velocidade m?dia na corrida de intensidade autorregulada m?xima de 5 km e a pot?ncia pico relativano teste de Wingate n?o foram diferentes entre as condi??es experimentais.A imers?o em ?gua a 15?C reduziu a Tret, a FC e os ?ndices de VFC a valores de repouso, ap?s a recupera??o.O EPOC foi maior na imers?o em ?gua a 15?C e a 28?C.Durante a corrida de intensidade autorregulada de 5 km e do teste Wingate, a Tret e a FC n?o foram diferentes entre as condi??es experimentais. A sess?o de exerc?cio experimental induziu dano muscular e leucocitose. Entretanto, n?o houve diferen?a nos n?veis s?ricos de CK, AST e no n?mero de leuc?citos totais entre as condi??es experimentais. A recupera??o por imers?o em ?gua,a diferentes temperaturas, n?o foi efetiva em modificar o desempenho f?sico 4 horas ap?s uma sess?o de exerc?cio prolongado. / Disserta??o (Mestrado) ? Programa Multic?ntrico de P?s-gradua??o em Ci?ncias Fisiol?gicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2012. / ABSTRACT Athletes of several sport modalities regularly train more than once a day. Several strategies have been used in order to accelerate post-exercise recovery. Although water immersion is a common strategy among athletes, it effectiveness in accelerate the recovery is not yet established, and the effects of temperature water immersion on performance are not clear. Thus, this study evaluated the effects of passive recovery water immersion at different temperatures on performance following an exercise session.Nine physically active men (24 ? 6 years old, 72 ? 13 kg, 177 ? 7 cm, peak oxygen consumption (VO2peak) of 55 ? 4 mL?kg-1?min-1), participated of four randomized experimental sessions. Each session consisted of eccentric knee flexion (3 x 10 repetitions of 100% from one maximum repetition) and 90 minutes of treadmill running at 70% of VO2peak, followed by 15 minutes of passive recovery by water immersion at 15?C, 28?C or 38?C and 30 minutes resting in supine position at room temperature (20 ? 2?C). In the control session, volunteers remained seated for 15 minutes at room temperature after exercise. After four hours of resting, in order to evaluate recovery strategies, the volunteers underwent a 5 km of maximal self-paced treadmill running followed by the Wingate test. Prior to experimental sessions, rested volunteers completed 5 km of maximal self-paced running and the Wingate test, which were used as reference performance values. Rectal temperature (Tret), heart rate (HR) and heart rate variability indexes (HRV indexes) were measured through the entire session. Excess post-exercise oxygen consumption (EPOC) was measured during recovery period. The markers of muscle damage, creatine kinase (CK) and aspartate aminotransferase (AST) and total leukocyte count were measured before and after exercise, after immersion, before and after performance tests, and 24 hours after the experimental exercise. Average speed during 5 km of maximal self-paced treadmill running and relative peak power during Wingate test were not different between experimental conditions. Water immersion at 15?C reduced Tret, HR and HRV indexes to baseline values after recovery. EPOC was higher in water immersion at 15?C and 28?C. During 5 km of maximal self-paced treadmill running and Wingate test, Tret and HR were not different between experimental conditions. The experimental exercise session induced muscle damage and leukocytosis. However, there was no difference in serum CK, AST and total leukocyte count between experimental conditions.The recovery by water immersion at different temperatures was not effective in modify the physical performance 4 hours after a session of prolonged exercise.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-04T16:04:23Z No. of bitstreams: 2 mariana_aguiar_matos.pdf: 3238462 bytes, checksum: 3f1d0300b61c8980e15bd5468c0ae135 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2016-01-04T16:05:17Z (GMT) No. of bitstreams: 2 mariana_aguiar_matos.pdf: 3238462 bytes, checksum: 3f1d0300b61c8980e15bd5468c0ae135 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2016-01-04T16:05:17Z (GMT). No. of bitstreams: 2 mariana_aguiar_matos.pdf: 3238462 bytes, checksum: 3f1d0300b61c8980e15bd5468c0ae135 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2012 / Funda??o de Amparo ? Pesquisa do estado de Minas Gerais (FAPEMIG) / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (Capes) / A maior quantidade de ?cidos graxos livres e de citocinas pr?-inflamat?rias plasm?tica presentes na obesidade, podem desencadear a resist?ncia a insulina, dentre outros fatores, pela fosforila??o inibit?ria do substrato do receptor de insulina 1 (IRS-1), via ativa??o de quinases relacionadas ao estresse, como a quinase C-jun N-terminal (JNK). Em obesos, a resist?ncia a insulina correlaciona-se com altera??es do sistema imune, e com a baixa express?o da prote?na de choque t?rmico de 72kDa (Hsp72) e aumento da ativa??o da JNK no m?sculo esquel?tico. Considerando que o exerc?cio f?sico aer?bico promove melhora da sensibilidade a insulina e tem um efeito anti-inflamat?rio. O objetivo desse estudo foi avaliar os efeitos de uma sess?o de exerc?cio f?sico aer?bico na express?o da HSP70, ativa??o da JNK e fosforila??o do IRS-1 no res?duo de serina 612 (IRS-1 ser612) no m?sculo esquel?tico de obesos. Al?m disso, foi avaliada a frequ?ncia dos linf?citos T auxiliares (CD4+) e citol?ticos (CD8+) e das subpopula??es de mon?citos cl?ssicos (CD14++CD16-), intermedi?rios (CD14++CD16+) e n?o cl?ssicos (CD14+CD16++). Os participantes do estudo (n=27) foram alocados em tr?s grupos experimentais (eutr?ficos sens?veis a insulina, obesos sens?veis a insulina, obesos resistentes a insulina) de acordo com a classifica??o do estado nutricional, de acordo com o ?ndice de massa corporal e presen?a ou n?o de resist?ncia a insulina, definida pelo modelo de avalia??o da homeostase (HOMA1-IR). Amostras de sangue venoso e do m?sculo vasto lateral foram obtidas antes e ap?s uma sess?o de exerc?cio f?sico aer?bico realizado a 60% do VO2pico,em cicloerg?metro, com dura??o de 60 minutos. Para avaliar a frequ?ncia das diferentes popula??es de mon?citos e linf?citos T circulantes utilizou-se a citometria de fluxo. As an?lises da express?o da HSP70, ativa??o da JNK e fosforila??o do IRS-1 ser612 no m?sculo esquel?tico foram feitas pelo procedimento de western blot. Nossos resultados demonstraram que obesos resistentes a insulina apresentam uma maior frequ?ncia de mon?citos intermedi?rios e maior fosforila??o do IRS-1 ser612 comparado aos eutr?ficos, maior ativa??o da JNK e menor express?o da HSP70 em rela??o aos demais grupos. Ap?s 1 hora do t?rmino da sess?o de exerc?cio aer?bico houve redu??o da frequ?ncia dos mon?citos intermedi?rios (CD14++CD16+) e dos linf?citos auxiliares (TCD4+) circulantes. Adicionalmente, a sess?o de exerc?cio induziu no m?sculo esquel?tico maior express?o da HSP70, redu??o da fosforila??o do IRS-1 ser612 nos grupos de indiv?duos obesos e menor atividade da JNK nos obesos resistentes a insulina. Conclui-se que uma sess?o de exerc?cio aer?bico promove altera??es que caracterizam redu??o da inflama??o e/ou estresse celular, que podem contribuir para a modula??o da sensibilidade a insulina promovida pelo exerc?cio f?sico. / Disserta??o (Mestrado) ? Programa Multic?ntrico de P?s-gradua??o em Ci?ncias Fisiol?gicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2012. / ABSTRACT The great amount of free fatty acids and proinflammatory cytokines present in obese individuals may trigger insulin resistance, through the inhibitory phosphorylation of insulin receptor substrate 1 (IRS-1), via activation of kinases related to stress, such as kinase C-Jun N-terminal (JNK). In obese individuals, insulin resistance correlates with alterations of the immune system and lower expression of the heat shock protein of 72kDa (Hsp72) and increased activation of JNK in skeletal muscle. Considering that aerobic exercise improve insulin sensitivity and has an anti-inflammatory effect, the purpose of this study was to evaluate the effects of a bout of aerobic exercise in the expression of HSP70, activation of JNK and phosphorylation of IRS-1 in serine residue 612 (IRS-1 ser612) in skeletal muscle of obese patients. Furthermore, we assessed the frequency of helper T lymphocytes (CD4 +) and cytolytic (CD8 +) and subpopulations of classical (CD14 + + CD16-), intermediate (CD14 + + CD16 +) and non-classical (CD14 + CD16 + +) monocytes. Study participants (n = 27) were divided into three experimental groups (eutrophic sensitive to insulin, insulin-sensitive obese, insulin-resistant obese) according to the classification of nutritional status, according to the body mass index, and the presence or absence of insulin resistance, defined by the homeostasis assessment model (HOMA1-IR). Venous blood and vastus lateralis samples were obtained before and after a bout of aerobic exercise performed at 60% of VO2peak on a cycle ergometer, lasting 60 minutes. To assess the frequency of the different populations of monocytes and T lymphocytes circulating we used flow cytometry. Analyses of of HSP70 expression, JNK activation and IRS-1 phosphorylation of ser612 in skeletal muscle were performed by western blot. Our results showed that obese insulin resistant subjects have an increased frequency of intermediate monocytes and higher phosphorylation of IRS-1 ser612 compared to normal weight individuals, and greater activation of JNK and lower expression of HSP70 than the other two groups. 1 hour after the exercise bout, we observed reductions on the frequency of intermediate circulating monocytes (CD14 + + CD16 +) and helper cells (CD4 +). Additionally, the exercise bout induced in the skeletal muscle higher expression of HSP70, decreased phosphorylation of IRS-1 ser612 in the obese groups and lower activity of JNK in the obese insulin resistant individuals. It is concluded that a bout of aerobic exercise promotes changes that characterize reduction of inflammation and / or cellular stress, which may contribute to the modulation of insulin sensitivity promoted by exercise.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-04-26T19:45:45Z No. of bitstreams: 1 PriscillaRiqueFurtado_DISSERT.pdf: 1546748 bytes, checksum: a3509e4944fe4fbcd3d434243426a399 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-04-29T19:38:25Z (GMT) No. of bitstreams: 1 PriscillaRiqueFurtado_DISSERT.pdf: 1546748 bytes, checksum: a3509e4944fe4fbcd3d434243426a399 (MD5) / Made available in DSpace on 2016-04-29T19:38:25Z (GMT). No. of bitstreams: 1 PriscillaRiqueFurtado_DISSERT.pdf: 1546748 bytes, checksum: a3509e4944fe4fbcd3d434243426a399 (MD5) Previous issue date: 2015-03-20 / Introdu??o: A determina??o da qualidade de vida (QV) de crian?as asm?ticas ? importante, pois, a asma grave ou com sintomas mal controlados, pode impedir a participa??o em atividades esportivas, prejudica o sono e o rendimento escolar, o que contribui para uma qualidade de vida ruim9 . Objetivos: Avaliar a rela??o entre qualidade de vida, capacidade de exerc?cio, e qualidade de sono de crian?as asm?ticas. Materiais e m?todos: Trata-se de um estudo observacional do tipo anal?tico transversal. A dispneia e a fadiga de membros inferiores foi alvaliada atrav?s da Escala 10-point Borg category-ratio (CR10); a espirometria, utilizando um espir?metro port?til digital KOKO? (Longmont, Estados Unidos da Am?rica); a qualidade de sono e presen?a de dist?rbios do sono, utilizando a Escala de dist?rbio de sono para crian?as (EDSC); a capacidade funcional, pelo teste do degrau de 6 minutos (TD6); e a qualidade de vida pelo Question?rio sobre a Qualidade de Vida na Asma Pedi?trica (QQVAP). O aceler?metro Actilife GT3X foi usado para classifica??o do n?vel de atividade f?sica. Foi utilizado o SPSS 17, n?vel de signific?ncia de 5%, e o teste de Kolmogorov-Smirnov para normalidade de dados. A estat?stica descritiva se deu atrav?s de m?dias, desvio padr?o e porcentagem. Os testes ?t? e ANOVA oneway foram usados para an?lises comparativas da qualidade de vida. O coeficiente de correla??o de Pearson foi utilizado entre as vari?veis quantitativas e os escores do QQVAP. Foram realizadas an?lises de regress?o linear m?ltipla (m?todo backward) entre as vari?veis que se correlacionaram. Resultados: Participaram 45 crian?as asm?ticas de ambos os sexos (60% - masculino), de faixa et?ria entre 7-12 anos. Dentre elas, 51,1% tinham asma de intermitente ? leve, e 48,9% tinham asma moderada ? grave. Os dist?rbios observados foram: Dist?rbio respirat?rio de sono (n=20), Hiperhidrose do sono (n=12), e Dist?rbio de in?cio e manuten??o do sono (n=2). A amostra foi composta por 71,1% de crian?as sedent?rias ou com n?vel de atividade f?sica leve. A m?dia de TD6-T foi 175,9?32,9. As m?dias do QQVAP para o escore Total, e dom?nios: sintomas (S), limita??o de atividades (LA) e Fun??o emocional (FE), foram respectivamente, 5,5?1,2; 5,6?1,3; 4,9?1,4; 5,7?1,3. A gravidade da asma, a qualidade de sono, e ? dispneia sentida ap?s o TD6, explicaram 31% da varia??o do escore total do QQVAP, e 35,6% do dom?nio de sintomas. A dispneia ap?s o 60 minuto de TD6 explicou a 7,2% para o dom?nio LA, e a gravidade em conjunto com o sono, explicaram 16,2% para o escore FE. Conclus?o: Os achados do presente estudo sugerem que em crian?as asm?ticas, a qualidade de vida pode estar relacionada ? gravidade da asma, a qualidade de sono, e ? dispneia sentida ap?s exerc?cios f?sicos. / Introduction: The determination of the quality of life (QoL) of asthmatic children is important because, severe or poorly controlled asthma symptoms, may prevent participation in sports activities, impairs sleep and school performance, which contributes to worse quality of life. Objectives: To evaluate the relationship between quality of life, exercise capacity, and quality of asthmatic children sleep. Objectives: To avaluate the relationship between quality of life, exercise capacity and capacity of sleep of asthmatic children. Methods: This study is an observational cross sectional. Dyspnea and fatigue of the lower limbs were assessed by the 10-point Borg scale category-ratio (CR 10); spirometry, using a digital portable spirometer KOKO? (Longmont, United States of America); quality of sleep and presence of sleep disorders, using The Sleep Disturbance Scale for Children (SDSC); for functional capacity, the 6MST was used; and for quality of life, the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). The accelerometer Actilife GT3X was used for physical activity level classification. We used the SPSS 17, assigning the significance level of 5%, and Kolmogorov-Smirnov test for normality of data. Descriptive statistics are given as mean, standard deviation and percentage. The "t" test and oneway ANOVA were used for comparative analysis of the quality of life. The Pearson correlation coefficient was used between quantitative variables and PAQLQ scores. Multiple linear regression analysis (backward method) between the variables that correlated were made. Results: were 45 asthmatic children of both sexes (60% - male), at age 7-12 years. Among them, 51.1% had asthma intermittently to light, and 48.9% had moderate to severe asthma. The following sleep disorders were observed: sleep-disordered breathing (n = 20), sleep hyperhydrosis (n = 12), and disorders of initiating and maintaining sleep (n = 2). The sample consisted of 71.1% of sedentary children or with low physical activity level. The 6MST-T average was 175.9 ? 32.9. QQVAP mean for the Total score and domains: symptoms, activity limitation (AL) and emocional function (EF) were, respectively, 5.5?1.2; 5.6?1.3; 4.9?1.4; 5.7?1.3. Asthma severity, sleep quality, and dyspnea felt after 6MST, explained 31% of the change in total score QQVAP, and 35.6% of domain symptoms. Dyspnea after 6 minutes of TD6, 7.2% for the AL field and gravity level in combination with sleep, to 16.2% explained EF score. Conclusion: The findings of this study suggest that in asthmatic children, the quality of life may be related to asthma severity, sleep quality, and dyspnea felt after exercise.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-06-15T00:36:47Z No. of bitstreams: 1 RafaelaCatherineDaSilvaCunhaDeMedeiros_DISSERT.pdf: 2269062 bytes, checksum: db9ca56020240e0009f73a1eb4b87c47 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-06-20T20:00:27Z (GMT) No. of bitstreams: 1 RafaelaCatherineDaSilvaCunhaDeMedeiros_DISSERT.pdf: 2269062 bytes, checksum: db9ca56020240e0009f73a1eb4b87c47 (MD5) / Made available in DSpace on 2016-06-20T20:00:27Z (GMT). No. of bitstreams: 1 RafaelaCatherineDaSilvaCunhaDeMedeiros_DISSERT.pdf: 2269062 bytes, checksum: db9ca56020240e0009f73a1eb4b87c47 (MD5) Previous issue date: 2015-07-03 / O aumento da incid?ncia, juntamente com as novas terapias para o HIV/AIDS trazem de maneira ascendente o exerc?cio f?sico como modalidade terap?utica. Esse, promove altera??es relevantes como regula??o do sono, aumenta as capacidades funcionais e aer?bicas, auxilia na manuten??o da fun??o imune, atenua os efeitos adversos da terapia antirretroviral, melhorando, consequentemente, a qualidade de vida desses indiv?duos. O objetivo do presente estudo foi avaliar, em diferentes per?odos, a influ?ncia do exerc?cio f?sico na qualidade de vida e qualidade do sono de pessoas vivendo com HIV/AIDS. A amostra foi composta por 17 pessoas vivendo com HIV/AIDS, acompanhadas longitudinalmente por 25 meses. Os volunt?rios foram submetidos as avalia??es da qualidade de vida, qualidade do sono e par?metros imunol?gicos, sendo ent?o reavaliados durante os per?odos de 2-4 meses (curto per?odo), de 5-17 meses (m?dio per?odo ou intermedi?rio) e por fim, de 19-25 meses (longo per?odo). Os resultados evidenciaram diferen?as significativas em 5 dos 9 dom?nios da qualidade vida, apontando comportamentos positivos, especificamente nos dom?nios fun??o geral, satisfa??o com a vida, preocupa??es com a sa?de, preocupa??es com a medica??o, aceita??o ao HIV e na qualidade de vida total. Houveram mudan?as e comportamentos positivos nos aspectos da qualidade do sono e par?metros imunol?gicos. Conclu?mos que o exerc?cio f?sico promoveu benef?cios tanto a curto como ? longo prazo, principalmente em dom?nios da qualidade de vida de pessoas vivendo com HIV/AIDS. / The increased incidence along to new therapies for the treatment of HIV/AIDS bring way up exercise as a treatment option, as this promotes relevant changes in the general functioning of the body. The objective of this study was to evaluate in different periods the influence of exercise on quality of life and quality of sleep people living with HIV/AIDS, Natal/RN. The sample consisted of 17 people living with HIV/AIDS participating in physical exercise program, along accompanied by 25 months during the period January 2013 to April 2015. We evaluated through specific instruments quality of life, sleep quality and immunological parameters, which were evaluated before starting the exercise program and reassessed during periods of 2-4 months (short), 5-17 months (average period or intermediate) and finally to 19-25 months (long period). The results showed significant differences in five of the nine areas of quality life, pointing positive behaviors, specifically in the areas overall function, life satisfaction, health concerns, concerns about the medication and acceptance to HIV. We conclude that physical exercise promoted benefits both in short and long term, especially for the areas of quality of life of people living with HIV/AIDS and also demonstrated positive behavior changes and to aspects of sleep quality.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-06-23T20:06:05Z No. of bitstreams: 1 DiegoDeLimaSousa_DISSERT.pdf: 2208966 bytes, checksum: 2885ffd2a2607c0a81d1654eca74abed (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-06-27T20:16:49Z (GMT) No. of bitstreams: 1 DiegoDeLimaSousa_DISSERT.pdf: 2208966 bytes, checksum: 2885ffd2a2607c0a81d1654eca74abed (MD5) / Made available in DSpace on 2016-06-27T20:16:49Z (GMT). No. of bitstreams: 1 DiegoDeLimaSousa_DISSERT.pdf: 2208966 bytes, checksum: 2885ffd2a2607c0a81d1654eca74abed (MD5) Previous issue date: 2016-01-28 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A medi??o de vaz?o atrav?s da predi??o da press?o diferencial ? amplamente utilizada no dia-a-dia industrial, isso acontece, principalmente, devido ao fato de ser utilizado para os mais variados tipos de fluidos, tais como: fluxo de gases e l?quido com viscosidades distintas, at? mesmo, escoamento de fluidos com part?culas em suspens?o. A adequa??o desses equipamentos para a medi??o de vaz?o m?ssica em escoamentos bif?sicos ? de suma import?ncia para o desenvolvimento tecnol?gico e confiabilidade dos resultados. Quando se trata de escoamentos bif?sicos as rela??es existentes entre os fluidos e as intera??es entre eles s?o de suma import?ncia na predi??o da vaz?o. No presente trabalho, ? proposto a utiliza??o de placa de orif?cio conc?ntrica utilizada em tubula??es de pequenos di?metros da ordem de 25,4 mm onde escoa um fluxo bif?sico de ?gua e ar. A medi??o de vaz?o monof?sica foi feita com a utiliza??o dos dados referentes na norma NBR 5167-1 onde utilizou-se a equa??o de Stolz para a mensura??o do coeficiente de descarga. No escoamento bif?sico foi utilizado duas correla??es largamente empregadas no progn?stico da vaz?o m?ssica, o padr?o de Zhang (1992), e o modelo de Chisholm (1967), para o modelo de escoamento homog?neo. Observou-se que o comportamento encontrado no modelo de Zhang, condizem de forma mais real?stica a vaz?o m?ssica do fluxo bif?sico, pois, o modelo de Chisholm extrapola nos par?metros para a press?o a jusante, P2, a placa de orif?cio, assim como o coeficiente de descarga avaliada. A utiliza??o da modifica??o nas quedas de press?o, P1-P2, e coeficiente de descarga, permitiu uma melhor converg?ncia entre os valores obtidos para o fluxo bif?sico ?gua-ar. / The measurement of flow through the prediction of differential pressure is widely used in industrial day-to-day, this happens mainly due to the fact that it is used for various types of fluids, such as gas flow and liquid with viscosity distinct even flow of fluids with particles in suspension. The suitability of this equipment for measuring mass flow in two-phase flow is of paramount importance for technological development and reliability of results. When it comes to two-phase flow the relationship between the fluids and their interactions are of paramount importance in predicting the flow. In this paper, we propose the use of concentric orifice plate used in small diameter pipes of 25.4 mm order where a two-phase flow flows between water-air. The measurement of single-phase flow was made with the use of data in NBR 5167-1 which was used to Stolz equation for measuring discharge coefficient. In the two-phase flow was used two correlations widely used in the prognosis of mass flow, the pattern of Zhang (1992) and the model of Chisholm (1967), to the homogeneous flow model. It was observed that the behavior found in Zhang model are consistent more realistic way the mass flow of two-phase flow, since the model Chisholm extrapolate the parameters for the downstream pressure P2, the orifice plate, and the rated discharge coefficient. The use of the change in pressure drop P1-P2 and discharge coefficient, led to a better convergence of the values obtained for the two-phase air-water stream.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-07-25T23:29:05Z No. of bitstreams: 1 AndersonRodriguesDeOliveira_DISSERT.pdf: 2673961 bytes, checksum: 94e48d2aac9ebb6eb6d30bb575363364 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-08-04T22:39:37Z (GMT) No. of bitstreams: 1 AndersonRodriguesDeOliveira_DISSERT.pdf: 2673961 bytes, checksum: 94e48d2aac9ebb6eb6d30bb575363364 (MD5) / Made available in DSpace on 2016-08-04T22:39:37Z (GMT). No. of bitstreams: 1 AndersonRodriguesDeOliveira_DISSERT.pdf: 2673961 bytes, checksum: 94e48d2aac9ebb6eb6d30bb575363364 (MD5) Previous issue date: 2016-03-18 / Diabetes Mellitus (DM) ? um grupo de doen?as caracterizada por anormalidades metab?licas e complica??es cr?nicas. A hiperglicemia caracter?stica dessa doen?a produz glicosila??o de prote?nas e consequente ac?mulo de produtos finais da glicosila??o em v?rios tecidos humanos, entre eles, o tend?o. O exerc?cio aer?bio (EA) e a terapia laser de baixa intensidade (TLBI) t?m sido utilizados no manejo de tendinopatias em indiv?duos com ou sem DM. Objetivo: O objetivo desse estudo ? observar o efeito da TLBI e o EA, associados, no processo de reparo tecidual do tend?o de Aquiles (TA) de ratos diab?ticos. M?todos: Foram utilizados 91 animais divididos nos seguintes grupos: grupo controle (GC), grupo controle lesionado (GCL), grupo diab?tico (GD), grupo diab?tido laser (GDL), grupo diab?tico treinado (GDT) e grupo diab?tico treinado laser (GDTL). De acordo com o grupo, os ratos foram submetidos interven??o do EA, TLBI ou associa??o dos dois recursos. Foram analisadas as caracter?sticas morfol?gicas, biomec?nicas e moleculares. Resultados: O peso final dos animais diab?ticos foi estatisticamente menor quando comparado com os animiais controles (p <0,01). A glicemia dos animais diab?ticos foi estatisticamente maior quando comparado aos grupos controles (p<0,01). Os testes biomec?nicos indicaram melhoras significativas nos animais dos grupos GC e GDTL quando comparados aos grupos diab?ticos nas vari?veis de carga m?xima, distens?o, energia absorvida, stress, ?rea de sec??o transversa, m?dulo el?stico e densidade de energia (p<0,05). A an?lise por meio de biologia molecular indicou que a associa??o do exerc?cio aer?bio e Laser promoveu aumento da express?o g?nica de col?geno I e modulou a express?o das MMP2 e MMP9. N?o foi observada melhora significativa nas vari?veis morfol?gicas estudadas. Conclus?o: a TLBI associada ao exerc?cio aer?bio promove melhora nas propriedades mec?nicas e no controle da express?o g?nica do col?geno I e da MMP2 e MMP9 de ratos diab?ticos. Palavras-chave Diabetes Mellitus. Fototerapia. Exerc?cio. Tend?o de Aquiles. Cicatriza??o / Diabetes Mellitus (DM ) is a complex disease that requires continuous medical care for the reduction of risk factors in addition to glycemic control. The typical hyperglycemia of this disease produces glycosylation of proteins and so the consequence is the accumulation of glycosylation final products in various human tissues, among them, the tendon. The aerobic exercise (AE) and the low level laser therapy (LLLT) have been used to treat tendinopathies in individuals with or without DM. Objective: The aim of this study was to watch the effect of the LLLT and the AE, in association, in partial tenotomy of the tissue repair of the Achilles tendon (AT) of diabetic rats. Methods: 91 animals were utilized and divided in to the following groups: control group (GC), injured control group (GCL), diabetic group (GD), diabetic group LLLT (GD ? TLBI), diabetic group trained (GD - EX) and diabetic group trained laser (GD-EX+TLBI). The animals were submitted to intervention with AE, using a protocol with a progressive increase of time (12 to 60 min) and speed of (4 to 9 m/min), and the LLLT (660 nm laser, 10mW, 4 J/cm?, single point for 16 seconds, three times for week). It was analyzed morphological, biomechanical and molecular characteristics. For data showing normal distribution was used one-way ANOVA test and post hoc Tukey and data without normal distribution was used Mann Whitney test and post hoc Dunn's. It was accepted p <0.05 for statistical significance Results: The biomechanical tests indicated major improvement in the GC and GD-EX+TLBI groups when compared with the diabetic groups in the following variables: maximum load, strain, absorbed energy, stress, cross section area, elastic modulus and energy density (p<0.05). The analysis through molecular biology indicated that the association of aerobic exercise and LLLT generated an increase of the collagen I gene expression and modulated the expression of the MMP2 and MMP9 (p<0.05). No observed any major improvement in the morphological variable studied. Conclusion: the LLLT associated with aerobic exercise promotes and increase of the mechanical properties, in the control of collagen I gene expression and of the MMP2 and MMP9 of the diabetic rats.

Made available in DSpace on 2014-12-17T14:52:44Z (GMT). No. of bitstreams: 1 ThiagoJAL.pdf: 723589 bytes, checksum: f29a9df6e168b3cfcaeac69b80136c28 (MD5) Previous issue date: 2009-02-27 / Deregulation of the sugar-alcohol sector in the 90s meant that agribusiness firms begin a process of reorganization of their production structures to enhance their abilities to become competitive in the new scenario. This study aims to examine the Production Chain of Sugar cane in Agreste region of Rio Grande do Norte, with studies to contribute to the competitiveness of farmers giving grants for planning and implementing policies, programs and projects, public and / or private. The method used in the study was researching the literature on the history of sugar cane in Brazil, agribusiness management, production chains and competitiveness, in field research used a questionnaire to collect information from farmers. It is concluded that the rural producers of cane sugar in newborns are not competitive and therefore it is necessary policies and / or for private gain in competitiveness of producers and consequently the production chain. It is hoped that the study serves as a subsidy for those policies proposi??o / A desregulamenta??o do setor sucroalcooleiro na d?cada de 90 fez com que as empresas agroindustriais iniciassem um processo de reorganiza??o das suas estruturas produtivas a fim de aumentar suas compet?ncias para torna-se competitivas no novo cen?rio. O presente estudo objetiva estudar a Cadeia Produtiva da Cana-de-a??car, na regi?o Agreste do Rio Grande do Norte, visando contribuir com estudos para a competitividade dos produtores rurais apresentando subs?dios para planejamento e implementa??o de pol?ticas, programas e projetos, p?blicos e/ou privados. O m?todo utilizado no estudo foi pesquisa da literatura existente sobre hist?ria da cana-de-a??car no Brasil, gest?o agroindustrial, cadeias produtivas e competitividade; na pesquisa de campo utilizou-se um question?rio para coletar informa??es dos produtores rurais. Conclui-se que os produtores rurais de cana-de-a??car do RN n?o s?o competitivos e por isso se faz necess?rio pol?ticas p?blicas e/ ou privadas para ganho de competitividade dos produtores e consequentemente da cadeia produtiva. Espera-se que o estudo sirva de subs?dio para proposi??o dessas pol?ticas

Made available in DSpace on 2014-12-17T15:12:08Z (GMT). No. of bitstreams: 1 AntonioJGF.pdf: 467077 bytes, checksum: 1405bda77b6c7763d645718e75052177 (MD5) Previous issue date: 2007-10-31 / Lucr?ce, penseur latin du si?cle I, avant J.C., ?crire que le peur de la mort imput? par la religion et la superstition, nourrit le souhait ? la richesse, l'ambition du pouvoir et les actes insens?s, dont les cons?quences se refl?tent dans les maladies de l'?me. La terreur qui s'installe chez l'homme, ? l'?tre confront? au d?c?s, est aussi un obstacle ? la libert? et ? la vie ?quilibr?e. Les craintes sans fondement seulement seraient surmonter, avec la compr?hension de la nature et du mouvement de l'?me, en percevant leur g?n?ration, corpor?it? et finitude. Pour cela, la compr?hension des atomes et du vide, les ?l?ments primordiaux de la nature se basent tout la connaissance de l'?me. L'objectif de ce travail est enqu?ter la nature de l'?me dans Lucr?ce, en pr?sentant une r?flexion sur les craintes sans fondement et la peur de la mort, comme une mani?re de percevoir le mouvement de la vie elle-m?me, et de que mani?re sa philosophie affronte ? la crainte de la mort. / Para Lucr?cio, pensador latino do s?c. I. a.C., o temor da morte imputado pela religi?o e as v?s supersti??es, alimenta o amor ? riqueza, a ambi??o do poder e os atos insensatos, cujas conseq??ncias se refletem nas doen?as an?micas. O terror que instala no homem, ao ser confrontado com a morte, ? tamb?m um obst?culo ? liberdade e ? vida equilibrada. Os temores infundados s? seriam desfeitos, com a compreens?o da natureza e do movimento da alma, percebendo a sua gera??o, corporeidade e finitude. Para isso, a compreens?o dos ?tomos e do vazio como elementos primordiais da natureza fundamentam todo o conhecimento da alma. O objetivo deste trabalho ? investigar a natureza da alma em Lucr?cio, apresentando uma reflex?o sobre os temores infundados e o medo da morte, como uma maneira de perceber o movimento da pr?pria vida, e de que modo a sua filosofia enfrenta o temor da finitude.

Made available in DSpace on 2014-12-17T15:34:48Z (GMT). No. of bitstreams: 1 LiviaACD_DISSERT.pdf: 1531134 bytes, checksum: c1e2d5ae497c2b82138de5eb2b97dad5 (MD5) Previous issue date: 2013-08-30 / The objective of this study was to characterize the socioeconomic profile of the family farmers who live and work in Brazilian rural space and highlight the importance of family agribusiness through the significant relation between some variables as the value of the total production, GDP share in total area of the establishments, agricultural production and farmer income, that show the important participation of these farmers in agricultural productivity and consequently on the economy of country. Therefore, this sector deserves a greater attention and more investment in the development of public policies that lead to a quality education in rural areas, availability of technical courses for farmers, technical assistance more efficient and effective, as well as funding more readily available / Objetivou-se com este trabalho, caracterizar o perfil socioecon?mico dos agricultores familiares que vivem e trabalham no espa?o rural brasileiro e destacar a import?ncia do agroneg?cio familiar atrav?s da rela??o entre algumas vari?veis significativas, como o valor da produ??o total, PIB, participa??o na ?rea total dos estabelecimentos, produ??o agropecu?ria e renda do agricultor, que mostram a importante participa??o destes agricultores na produtividade agropecu?ria e consequentemente na economia do pa?s. Portanto, este setor merece uma maior aten??o e mais investimentos no desenvolvimento de pol?ticas p?blicas que levem ? uma educa??o de qualidade no meio rural, disponibilidade de cursos t?cnicos para os agricultores; assist?ncia t?cnica mais eficiente e efetiva, assim como financiamentos de mais f?cil obten??o

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2018-03-12T19:37:13Z No. of bitstreams: 1 LidianeCristinaCorreiaBulhoes_DISSERT.pdf: 1256553 bytes, checksum: 8a1403a25ff7025a622f889416a372ea (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2018-03-16T15:25:26Z (GMT) No. of bitstreams: 1 LidianeCristinaCorreiaBulhoes_DISSERT.pdf: 1256553 bytes, checksum: 8a1403a25ff7025a622f889416a372ea (MD5) / Made available in DSpace on 2018-03-16T15:25:26Z (GMT). No. of bitstreams: 1 LidianeCristinaCorreiaBulhoes_DISSERT.pdf: 1256553 bytes, checksum: 8a1403a25ff7025a622f889416a372ea (MD5) Previous issue date: 2017-12-15 / Introdu??o: Os idosos tendem a apresentar redu??o no trofismo, na amplitude de ativa??o muscular e na for?a, o que pode impactar negativamente na sua funcionalidade. Estudos t?m sido realizados com exerc?cios na plataforma vibrat?ria, por?m, existe uma escassez na literatura no que se refere aos poss?veis efeitos neurofisiol?gicos agudos desta t?cnica em sujeitos idosos. Objetivo: Analisar os efeitos agudos de uma sess?o de exerc?cio na plataforma vibrat?ria sobre o desempenho neuromuscular dos membros inferiores em idosos. M?todos: Trata-se de um ensaio controlado, randomizado e cego, no qual 44 volunt?rios, de ambos os sexos, com idade m?dia de 68,5 ? 2,67 anos, foram submetidos a uma avalia??o da oscila??o postural (baropodometria), do desempenho isocin?tico e da atividade eletromiogr?fica dos m?sculos vasto lateral (VL) e s?leo, do membro dominante. Em seguida, foram distribu?dos aleatoriamente em dois grupos, com 22 participantes cada: grupo placebo (GP) ? executou um protocolo de exerc?cio com a plataforma desligada; e grupo experimental (GE) ? realizou um protocolo de exerc?cio com a plataforma ligada, numa frequ?ncia de 40 Hz e amplitude pico a pico de 4 mm. Ambos os grupos realizaram o mesmo protocolo de exerc?cios na plataforma, composto por 4 s?ries de 90 segundos de dura??o e intervalo de repouso de 1 minuto, em semi-agachamento bipodal est?tico, a 400 de flex?o de joelho. Ao final das interven??es os volunt?rios foram submetidos a uma reavalia??o id?ntica a realizada antes do protocolo de exerc?cios. Os dados foram analisados no software SPSS 21.0, atribuindo-se n?vel de signific?ncia de 5% (p ? 0,05). Para an?lise da normalidade dos dados foi usado o teste de Kolmogorov-Smirnov e para atestar a homogeneidade entre os grupos foi utilizado um teste ?t? para medidas independentes. Para compara??o intra e intergrupo foi utilizada uma ANOVA modelo misto. Resultados: Houve diferen?a significativa intergrupo no valor do RMS para o VL e intragrupo no RMS do s?leo, ap?s o protocolo de interven??o no GE. Na avalia??o do desempenho isocin?tico, o pico de torque dos extensores do joelho apresentou aumento intragrupo no GE e nos flexores plantares foi observado aumento intragrupo para o GP e GE; para a vari?vel pot?ncia houve aumento intragrupo, em ambos os grupos. N?o foi observada diferen?a significativa na oscila??o postural. Conclus?o: O protocolo de exerc?cio na plataforma vibrat?ria promove um maior recrutamento neuromuscular do vasto lateral em indiv?duos idosos. Entretanto, de maneira imediata, n?o foram observadas altera??es na oscila??o postural, nem no desempenho isocin?tico desses sujeitos. / Background: Elderly people tend to present a decrease of the trophism, amplitude of muscular activation and strength, which causes significant negative implications in their functionality. Studies about exercise on the whole body vibration have been performed, however, there is a lack in the literature regarding the possible neurophysiological acute effects of this technique in elderly people. Objective: To analyze the immediate effects of an exercise session on the vibratory platform on the lower limb neuromuscular performance of elderly. Methods: This is a ramdomized, blind, controlled trial, in wich 44 volunteers, of both genders, mean age of 68,5 ? 2,67 years, were submitted to an evaluation of the postural oscillation (baropodometry), isocinetic performance and electromyographic activity of the vastus lateralis (VL) and soleus muscle of the dominant limb. After, they were randomly assigned in two groups, with 22 participants each: placebo group (PG) ? underwent a series of exercises with the vibrating platform off; and experimental group (EG) - underwent a series of exercises with the vibrating platform on, configured at frequency of 40 Hz and a displacement amplitude of 4 mm. Both groups executed the same exercise protocol in the platform, composed of a bipodal isometric squat at 400 of knee flexion, being 4 series of 90 seconds of duration, with interval of 1 minute. At the end of the intervention, the volunteers were submitted to a re-evaluation identical to the previous performed before the exercise protocol. Data were analyzed using SPSS 21.0 software, assigning a level of significance of 5% (p ? 0,05). To the analysis of normality of data it was used the Kolmogorov-Smirnov test and to attest the homogeneity between groups, a paired-sample test t. To analyze the differences between and within group, it was used a mixed model ANOVA. Results: There was a significant between-group increase in RMS for the VL and within group for soleus RMS after the intervention protocol in the EG. For isokinetic performance, there was an within group increase in peak torque of knee extensors on EG and of plantar flexors on PG and EG; for the variable power, there was an within group increase in both groups. It was not observed significant differences on postural oscillation. Conclusion: The protocol of exercise on the whole-body vibration promotes a greater neuromuscular recruitment of VL muscles in elderly. However, it was not observed immediate effects on postural oscillation or in isokinetic performance in this population.