Este trabalho teve o objetivo de analisar retrospectivamente o significado da interseção de dois fenômenos sociomodernos. Em primeiro lugar, a epidemia de HIV/AIDS (Vírus da Imunodeficiência Humana/Síndrome de Imunodeficiência Adquirida), com suas características históricas pouco usuais e alta letalidade; e, por outro lado, a intrusão de leis de propriedade intelectual na sociedade, como o Acordo TRIPS (Trade Related Intellectual Property Subjects), com amplas repercussões sobre a saúde pública assim como sobre o desenvolvimento econômico e tecnológico dos países, sendo aqui tratados especificamente os casos de Brasil e México. Ambos os países modificaram suas leis de propiedade intelectual (LPI) para implementar o Acordo TRIPS (e, no caso do México, também o NAFTA) nas últimas duas décadas, levando a patamares mais elevados de proteção de propriedade intelectual no México, quando comparado ao Brasil. Estas mudanças, porém, podem ter contribuído, no caso do México, para um menor rendimento e eficácia do seu programa de combate à epidemia de AIDS/HIV já que, para dar uma cobertura mais adequada de tratamento com medicamentos antirretrovirais (ARVs) para sua população, teve que enfrentar maiores dificuldades para sua aquisição. / This work analyzed retrospectively the meaning of the intersection of two modern social phenomena. Firstly, the epidemic of HIV/AIDS (Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome), with its unusual historical characteristics and high lethality; and , on the other hand, the intrusion of intellectual property laws in society as the TRIPS (Trade Related Intellectual Property Subjects) Agreement, that has far-reaching consequences on public health as well as on the economic and technological development of countries, and here we treated specifically the cases of Brazil and Mexico. Both countries changed their intellectual property laws to implement the TRIPS Agreement (and in the case of Mexico also NAFTA) during the last two decades, leading to higher levels of intellectual property protection in Mexico compared to Brazil. However these changes may have contributed in the case of Mexico to a lower performance and effectiveness of its programme to combat the epidemic of HIV/AIDS, since to give a more adequate coverage of treatment with antiretroviral drugs (ARVs) for its population, had to face major difficulties for the purchase of these medicines.

L’analyse de la personnalité du dieu ouest-sémitique Rašap permet de suivre les étapes de l’évolution de sa figure divine. Son culte a connu une large diffusion dans tout le Levant et jusqu’en Égypte. Apparu au IIIe millénaire à Ebla, il s’éteint à la fin du Ier millénaire. La dernière attestation de son nom apparaît dans une inscription de l’an 6 av. J. C. à Palmyre. On tenait Rašap pour maître des activités militaires et responsable de la propagation des épidémies. Ce sont ces fonctions qui lui ont valu la pérennité qui lui est propre, entretenue par des guerres incessantes, entraînant fléaux et épidémies. Contrairement au sources textuelles égyptiennes, prolifiques, la littérature sémitique est plutôt avare d’informations et de descriptions relatives aux spécificités de Rašap. Toutefois, son rapprochement des différentes divinités connues, notamment de Nergal aux IIIe et IIe millénaires, dans le milieu syrien, et d’Apollon à l’époque classique chypriote, aide à mieux comprendre la personnalité de Rašap. Son nom est également mentionné dans la Bible hébraïque, accompagné de ceux d’autres êtres suprêmes : Bārād, Qeteb et Deber. Bien que les versets bibliques révèlent le côté guerrier et redoutable de celui qui est appelé en hébreu Rešep, l’aspect divin de ce dernier s’estompe graduellement, pour laisser place à un simple nom commun, dont la signification n’est pas toujours limpide, comme le prouve un certain passage du livre de Ben Sirah. Une riche iconographie rassemblée notamment à partir de documents proche orientaux et égyptiens (reliefs, statues, sceaux, amulettes) complète les données textuelles et confirme leur interprétation. / The analysis of the personality of the West Semitic god Rašap allows us to follow the evolution of its divine figure. His cult has known a large diffusion into the Levant and up to Egypt. It first appeared in the third millennium Ebla and extinguished at the end of the first millennium. The last occurrence of his name appears in a Palmyrene inscription dating from the year 6 B. C. Rašap was the master of military activities and responsible of widespread diseases. These particular qualities ensured his unbroken existence, without major disruption, maintained by conflicts between realms, thus causing contagious and epidemic diseases. Unlike plentiful textual Egyptian sources, Semitic documentation seems rather stingy with information and description of Rašap’s characteristics. Nevertheless, his relation with different deities, in particular Nergal at the 3rd and the 2nd Millennium in a Syrian context, and Apollo in Cyprus classical era, helps to define and outline Rašap’s personality. His name appears as well in the biblical texts, accompanied with other divine names, such as Bārād, Qeteb and Deber. Even if the biblical verses reveal the warrior and dreadful side of the so-called Rešep, his divine aspect fades away, to become afterwards a simple noun, as it is proved in the book of Ben Sirah. A rich Oriental and Egyptian iconographical documentation (reliefs, statues, seals, amulets) completes the textual sources and confirms their interpretation.

Introducao - Ha reduzido conhecimento no campo da Saude Publica sobre a funcao social da midia em saude e, particularmente, sobre a relacao entre a midia e o contexto de uma epidemia associada a vetores biologicos, como a dengue. Diante desse quadro, optou-se por estudar a primeira epidemia de dengue em Ribeirao Preto, a qual ocorreu entre novembro de 1990 e marco de 1991. O fato dessa epidemia, assim como as demais, ter sido estudada apenas em seu aspecto biologico, desconsiderando o aspecto social, justifica a realizacao deste estudo. Objetivo - Investigar como se deu a construcao midiatica da primeira epidemia de dengue no municipio de Ribeirao Preto, de novembro de 1990 a marco de 1991, para os leitores dos jornais e revistas veiculadas na epoca. Metodo O material de pesquisa foram reportagens de jornais e revistas confeccionadas na regiao de Ribeirao Preto e na capital do Estado de Sao Paulo - as de grande circulacao na epoca da primeira epidemia de dengue em Ribeirao Preto, de novembro de 1990 a marco de 1991. O metodo adotado foi o Discurso do Sujeito Coletivo, fundamentado na Teoria das Representacoes Sociais. Resultados Foram resgatadas as representacoes sociais veiculadas pela midia e o poder de difusao dessas representacoes no processo de divulgacao cientifica para o publico em geral durante a primeira epidemia de dengue. A analise do conteudo midiatico permitiu apresentar os principais assuntos veiculados no noticiario por meio da elaboracao dos discursos. Conclusoes Foi possivel entender como se deu a construcao dos sentidos acerca da dengue: o jornal fez existir uma realidade epidemica. Comprovou-se a defasagem na informacao disponibilizada nos meios de comunicacao e observou-se vies politico nas reportagens veiculadas, desviando a atencao que deveria ser direcionada para educacao e promocao da saude. Salientou-se a importancia de formacao de profissionais que transitem na interface Saude Publica e Comunicacao para que questoes politicas nao prevalecam sobre questoes prioritarias de saude na midia impressa / Introduction There is limited knowledge in the field of Public Health about the social role of media in health and particularly on the relationship between the media and the context of an epidemic associated with biological vectors such as dengue. So, it was decided to study the first epidemic of dengue at Ribeirao Preto, which occurred between November 1990 and March 1991. This epidemic, like the others, was studied only in its biological aspect, ignoring the social aspect, which justifies this study. Aim The aim of this study was to investigate how was the media construction of the first epidemic of dengue in Ribeirao Preto, from November 1990 to March 1991 for the readers of newspapers and magazines circulating at the time. Method The research material were reports of newspapers and magazines made at Ribeirao Preto and at the capital of the State of Sao Paulo - the large circulation - at the time of the first dengue epidemic at Ribeirao Preto, from November 1990 to March 1991. The method adopted was the Collective Subject Discourse, which is based on the Social Representations Theory. Results Social representations in the media were rescued in the media and also the power of diffusion of these representations in the process of scientific diffusion to the general public during the first dengue epidemic. The analysis of media content allowed to present the main issues in the newspapers and magazines through the speeches elaboration. Conclusions In this research, it could be understood how was the construction of meanings about dengue: the newspaper created a reality epidemic. The lag of information provided by mass media was proven and there was political bias in the news published, diverting the attention that should be directed towards education and health promotion. A professional transiting the interface Public Health and Communication is important so that political issues do not prevail on priority issues of health in printed media

O trabalho focaliza as controvérsias que se seguem ao evento da epidemia de cóleramorbus deflagrada na província de Pernambuco no ano de 1855, em torno de práticas e terapias que foram mobilizadas no combate à moléstia. O fio condutor da análise são os embates que se estabeleceram entre a medicina acadêmica e outras formas terapêuticas - particularmente de homeopatas, leigos, negros e índios. Adicionalmente, o trabalho procura pontos de intersecção entre a emergência de um projeto moderno de medicina e a religião, acompanhando a reflexão e a prática produzidas pelos missionários capuchinhos italianos sobre a epidemia. / The work focuses on the controversy following the event of the epidemic of choleramorbus triggered in the province of Pernambuco in the year 1855, around practices and therapies that have been mobilized to fight the disease. The guiding thread of the analysis are the shocks that have been established between academic medicine and other therapeutic methods - particularly of homeopaths, lay people, blacks and indians. Additionally, the work searches points of intersection between the emergence of a modern project of medicine and religion, accompanying the reflection and practice produced by italian capuchin missionaries on the epidemic.

Mathematical modeling of spreading processes have been largely studied in the literature, and its presented a boom in the past few years. This is a fundamental task on the understanding and prediction of real spreading processes on top of a population and are subject to many structural and dynamical constraints. Aiming at a better understanding of this processes, we focused in two task: the modeling and the analysis of both dynamical and structural aspects of these processes. Initially, we proposed a new and general model that unifies epidemic and rumor spreading. Besides, regarding the analysis of these processes, we extended the classical formalism to multilayer networks, in which the theory was lacking. Interestingly, this study opened up new challenges concerning the understanding of multilayer networks. More specifically, regarding their spectral properties. In this thesis, we analyzed such processes on top of single and multilayer networks. Thus, throughout our analysis, we followed three complementary approaches: (i) analytical, (ii) numerical and (iii) simulations, mainly Monte Carlo simulations. Our main results are: (i) a new unifying model, enabling us to model and understand spreading processes on large systems, (ii) characterization of new phenomena on multilayer networks, such as layer-wise localization and the barrier effect and (iii) an spectral analysis of multilayer systems, suggesting a universal parameter and proposing a new analytical tool for its analysis. Our contributions enable further research on modeling of spreading processes, also emphasizing the importance of considering the complete multilayer structure instead of any coarse-graining. Additionally, it can be directly applied on the prediction and modeling real processes. Thus, aside from the theoretical interest and its mathematical implications, it also presents important social impact. / A modelagem matemática dos processos de disseminação tem sido amplamente estudada na literatura, sendo que o seu estudo apresentou um boom nos últimos anos. Esta é uma tarefa fundamental na compreensão e previsão de epidemias reais e propagação de rumores numa população, ademais, estas estão sujeitas a muitas restrições estruturais e dinâmicas. Com o objetivo de entender melhor esses processos, nos concentramos em duas tarefas: a de modelagem e a de análise de aspectos dinâmicos e estruturais. No primeiro, propomos um modelo novo e geral que une a epidemia e propagação de rumores. Também, no que diz respeito à análise desses processos, estendemos o formalismo clássico às redes multicamadas, onde tal teoria era inexistente. Curiosamente, este estudo abriu novos desafios relacionados à compreensão de redes multicamadas, mais especificamente em relação às suas propriedades espectrais. Nessa tese, analisamos esses processos em redes de uma e múltiplas camadas. Ao longo de nossas análises seguimos três abordagens complementares: (i) análises analíticas, (ii) experimentos numéricos e (iii) simulações de Monte Carlo. Assim, nossos principais resultados são: (i) um novo modelo que unifica as dinâmicas de rumor e epidemias, nos permitindo modelar e entender tais processos em grandes sistemas, (ii) caracterização de novos fenômenos em redes multicamadas, como a localização em camadas e o efeito barreira e (iii) uma análise espectral de sistemas multicamadas, sugerindo um parâmetro de escala universal e propondo uma nova ferramenta analítica para sua análise. Nossas contribuições permitem que novas pesquisas sobre modelagem de processos de propagação, enfatizando também a importância de se considerar a estrutura multicamada. Dessa forma, as nossas contribuições podem ser diretamente aplicadas à predição e modelagem de processos reais. Além do interesse teórico e matemático, nosso trabalho também apresenta implicações sociais importantes.

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Dr. Robert Pack, associate dean for Academic Affairs in ETSU’s College of Public Health, joined leaders from public health schools in four other states in the Appalachian region to discuss with members of the U.S. Congress the complex and dynamic processes at work in the opioid crisis. Pack joined his colleagues in sharing findings on unique approaches to address the course of the epidemic as well as discuss how university-based public health experts are assisting affected communities by bringing traditional and novel epidemic control strategies to bear on the disease.