The purpose of the study was to test the hypothesis that dogs sensitized to soy antigen would produce significantly greater amounts of antigen specific IgE antibody compared to a control population before and after challenges with soy, hydrolyzed soy, and non-soy diets. Further, we sought to evaluate important allergenic components of soy using Western blot analysis. Lastly, absorption and mucosal function testing using inert sugars were evaluated for our sensitized and non-sensitized controls. Eight dogs (6 female, 2 male) were sensitized to whole soy using an established protocol. Seven dogs (3 female, 4 male) roughly age matched were used as controls. The dogs were randomly split into three groups. All dogs were fed an elimination diet of egg and Brewer's rice for six weeks. Samples were collected and each group was fed a diet of soy and rice flour, hydrolyzed soy and rice flour, or corn and rice flour for three weeks. Samples were collected and each group was fed the elimination diet followed by challenge with each of the diets. Serum was collected and stored for allergen specific IgE semi-quantitation and Western blot analysis using whole soy fractionated into globulin and whey components. A solution of monosaccharide and disaccharide sugars was administered in a volume determined by weight. Six hours after administration the dogs were catheterized and the entire urine volume was collected for measurement of sugar recovery by high pressure chromatography, followed by pulsed amphometric detection. There was a statistically significant difference in serum IgE between sensitized and control dogs after the elimination diet, and also for each of the challenged diets. There were differences detected by Western blot analysis for allergens within the soy globulin and whey fractions for sensitized dogs compared to control dogs. There were no significant differences between sensitized and control dogs for sugar recovery for any of the diets. We conclude that although there were significant differences in measurable IgE between sensitized and control dogs, we were unable to differentiate these groups using gastrointestinal mucosal permeability and function testing.

According to science, food allergy is a growing health problem. In home- and consumer studies (HCS), food and meals are central parts. According to the Education Act, teachers must be given professional development to create a safe environment for students.   The purpose of this study was to examine how teachers in home economics and consumer studies experienced the conditions for teaching students with food allergies. The focus was on the classroom, routines, allocated budget, and professional development.   Qualitative method was used. Nine qualified home economics teachers were interviewed based on a semi-structured question guide. The interviews were transcribed and analyzed with a qualitative content analysis.   The results showed that the classroom and the economic conditions limited the teaching. The teachers felt confident in their current knowledge but were positive about continuing education. Routine improvements regarding information management and action plan are desired.     The study showed that the classroom was important for the teaching and that the few students with food allergies did not affect the budget in general. Routines around these students should be reconsidered. Basic education needs to be strengthened and teachers need to be given the opportunity for further training.

Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2016-09-19T13:36:37Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) COLACAO FINAL.pdf: 6155295 bytes, checksum: 72b54a0d2d74622812225c02c45a9105 (MD5) / Made available in DSpace on 2016-09-19T13:36:37Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) COLACAO FINAL.pdf: 6155295 bytes, checksum: 72b54a0d2d74622812225c02c45a9105 (MD5) Previous issue date: 2016-02-05 / O anel na derivação gástrica em Y de Roux (DGYR) pode levar a intolerância alimentar, mesmo na ausência de estenose, sendo sua remoção cirúrgica o tratamento habitual. Objetivou-se avaliar a viabilidade, eficácia e segurança da dilatação endoscópica do anel com balão de acalasia – Rigiflex®, bem como a evolução ponderal que se segue ao procedimento. Procedeu-se a um estudo longitudinal retrospectivo, com avaliação de dados coletados prospectivamente. A coorte estudada foi submetida ao procedimento proposto no Hospital das Clínicas da UFPE, entre 2002 e 2011, sendo composta por pacientes advindos de serviços de cirurgia bariátrica, em diferentes regiões do Brasil. Foram incluídos 63 pacientes (45 mulheres e 18 homens), com média de idade de 42,4 anos, com quadro de vômitos pós-alimentares em frequência superior a quatro episódios semanais. A efetividade do método baseou-se na melhora dos sintomas obstrutivos, tendo sido empregadas até quatro sessões. Avaliou-se a evolução do índice de massa corporal (IMC), do percentual de excesso de peso (%EP) e do percentual de perda de excesso de peso (%PEP) da amostra em relação aos períodos pré-operatório, da dilatação e do seguimento tardio. Houve melhora completa da sintomatologia inicial em 59 casos (93,6%) e parcial, em dois casos (3,2%). Houve complicações leves em seis casos (9,6%), todos tratados clinicamente. Após seguimento mediano de 43 meses houve incremento médio no IMC de 2,5 kg/m². A dilatação endoscópica com balão, método minimamente invasivo, mostrou-se viável, segura e eficaz, observando-se pequeno aumento ponderal na avaliação tardia. / The placement of a ring on Roux-en-y gastric bypass (RYGB) can lead to food intolerance, even in the absence of stenosis, and its surgical removal is the usual treatment. The purpose of this retrospective, longitudinal study, which evaluated prospectively collected data, was to evaluate the feasibility, efficacy and safety of endoscopic ring dilation with achalasia balloon - Rigiflex®, as well as the weight gain following the procedure. The patients enrolled in this cohort came from different bariatric services in Brazil and underwent the proposed procedure at Hospital das Clínicas of UFPE, between 2002 and 2011. Sixty three patients (45 women and 18 men) with a mean age of 42.4 years who had more than four post-prandial vomiting episodes per week were included. The effectiveness of the method was based on the improvement in obstructive symptoms, after up to four sessions. The body mass index (BMI), the percentage of excess weight (% EW) and the percentage of excess weight loss (% EWL) of the subjects were evaluated in relation to the preoperative period, the dilation moment and the late follow-up. There was full improvement of the initial symptoms in 59 cases (93.6%) and partial, in two cases (3.2%). Minor complications were observed in six cases (9.6%), which were all treated clinically. After median follow-up of 43 months there was an average BMI increase of 2.5 kg / m². Endoscopic balloon dilation, which is a minimally invasive method, proved to be feasible, safe and effective with a slight weight gain in late evaluation.

Food-related diseases, including food allergies and food intolerances, are on the rise worldwide. According to the World Health Organisation (WHO), allergic diseases in the economically advanced countries of the WHO have become the largest child environmental epidemic. Dysregulation of immune tolerance is the basic mechanism involved in the development of food allergy. It is believed that the risk of developing allergies is more related to other lifestyle factors such as a diet, physical activity or obesity. Food allergies in children and adult populations vary both in the spectrum of triggering foods and also their symptoms and their severity. The prognosis also differs in allergies for different types of foods. One of the most important factors affecting the correct development of the baby's immune system is nutrition. In the first 4 - 6 months, the baby should only receive breast milk - for infants it is the most appropriate and allergenically safe diet. It strengthens their immune system. Its positive effect is observed especially on the occurrence of food allergies and atopic eczema. However, developing asthma and other allergies may not be prevented. Breastfeeding has an extraordinary importance and benefits in preventing many illnesses for both the child and the mother. Milk is a major food...

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Submitted by Natalia de Souza Gonçalves (natalia.goncalves@ufpe.br) on 2016-10-10T13:09:11Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) GALENO EGYDIO - COLACAO DE GRAU.pdf: 1509311 bytes, checksum: f4dc67e7a0e6a1a9159df433631ba569 (MD5) / Made available in DSpace on 2016-10-10T13:09:12Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) GALENO EGYDIO - COLACAO DE GRAU.pdf: 1509311 bytes, checksum: f4dc67e7a0e6a1a9159df433631ba569 (MD5) Previous issue date: 2014-02-19 / O uso de anel na derivação gástrica em Y de Roux (DGYR) está associado à intolerância alimentar pós-operatória, cujo tratamento clássico tem sido a remoção cirúrgica. Um novo método utilizando prótese plástica autoexpansível (PPAE) induz erosão intragástrica do anel, o qual é removido por via endoscópica de forma minimamente invasiva. Objetiva-se analisar a eficácia e a segurança dessa técnica de remoção de anel após DGYR. Estudo prospectivo longitudinal de série de 41 pacientes com intolerância alimentar associada à presença de anel, que foram, tratados por via endoscópica, entre 2007 e 2013. O grupo apresentava média de idade igual a 44,1 anos, IMC médio de 27,0 Kg/m², e vômitos foram os sintomas mais frequentes (n=37), com ocorrência diária em 46,3%. O sucesso terapêutico foi definido como a melhora dos sintomas após a remoção do anel. O implante de PPAE foi realizado sob anestesia geral e guiado por radioscopia, sendo utilizado endoscópio padrão. Os pacientes receberam alta após 24 horas com dieta líquida e inibidor de bomba de prótons (IBP), que foi prescrito durante o tempo médio de permanência da PPAE, que foi de 15,3 dias. A prótese promoveu erosão completa de anel em 24 (58,5%) pacientes e no grupo restante, a remoção em segundo estágio após 7 dias com pinça de corpo estranho. Houve três casos de migração da prótese com eliminação espontânea por via retal. O efeito adverso mais comum foi vômito (n=7). Não houve complicações graves, nem necessidade de remoção precoce da prótese. Após seguimento médio de 6 meses, não houve mudança significativa no IMC e 78% dos pacientes foram capazes de ingerir carne vermelha. A remoção do anel com uso de prótese endoscópica demonstrou ser um procedimento seguro e eficaz, com100% dos anéis sendo removidos com sucesso e 29,3% de ocorrência de eventos adversos leves (vômitos). Esta técnica é uma alternativa adequada na remoção do anel, evitando a intervenção cirúrgica e reduzindo a possibilidade de reganho de peso. / Ring dysfunction after roux-en-y gastric bypass (RYGB) causing delayed gastric emptying on Fobi pouch is classically treated by surgical ring removal. In a novel way of using selfexpandable stents, intraluminal erosion of the ring is achieved, allowing its removal by endoscopy, with no need of surgery. No study has shown clinical applicability of this principle in RYGB banded with silastic ring. In this case series we analyze endoscopic removal of noneroded dysfunctional rings after RYGB using self-expandable plastic stents (SEPS). This is a prospective case series of 41 patients with delayed gastric emptying secondary to extrinsic compression of the ring after RYGB between 2007 and 2013. Successful ring removal, symptoms improvement, weight control and adverse events were evaluated. Mean age of subjects was 44.1 years, median BMI at treatment was 27.0 Kg/m2. Most common symptom was vomiting (n=37), with daily occurrence in 46.3%. Success was defined as symptoms improvement after stent and ring removal. SEPS placement was done under general anesthesia and fluoroscopic guidance. A standard gastroscope (Pentax Medical, Montvale, NJ), and a PolyflexTM stent (25x21x150mm) (Boston Scientific, Natick, MA) were used in all cases. All patients were discharged after a 2-hour observation period, with liquid diet and proton pump inhibitor. SEPS induced complete erosion in 24 patients, allowing for simultaneous stent and ring removal. The median time of stenting was 15 days. There was one case of stent migration, which was naturally expelled. Most common adverse event was vomiting (n=7). There was no early stent removal, and no serious complications. After a mean follow-up of 6 months, there was no significant change in mean BMI, and 78% of patients are able to ingest solid foods. Endoscopic stents led to ring intraluminal erosion in 100% of subjects, allowing for successful removal of dysfunctional rings. The procedure is technically feasible and safe, with a 29.3% occurrence of mild adverse events (vomiting), and no serious complications. It proved to be a reasonable alternative for ring removal in our casuistic, avoiding surgery, and decreasing the possibility of weight regain.