Fresenius Kabi is a company specializing in clinical nutrition, infusion therapy and medicinal technology. Fresenius Kabi has two production facilities in Sweden, one in Brunna and one in Uppsala. The production facility in Brunna supplies the facility in Uppsala with the raw materials needed to create ampules of anesthetics, bags of parental nutrition, vitamin solutions and many other medicinal products. Fresenius Kabi has recently made a big investment in a software program called PAS-X which is designed to store and control the flow of information during production of the company’s various products. This information is currently written by hand on paper in batch protocols and stored for up to 10 years as part of the company’s quality assurance. The problem with PAS-X and the motivation behind this thesis project is that the production and production information therein is not optimized to be controlled electronically. The production layout and processflow have been largely adapted with manual information storage in mind, making a direct transition to electronic storage problematic. This project was ordered by the PAS-X project group at Fresenius Kabi where the goals were to analyze the production layout and production flow and subsequently rearrange the production layout and revise the process using a LEAN methodology. By identifying and eliminating areas of waste and also standardizing the production of one of the company’s main products, SMOFKabiven, this thesis and the work behind it was able to theoretically reduce transportation distance during key moments by 65 %, the time to complete selected operations by 40 % and manpower necessity by 50 % in 75 % of analyzed work operations.

Laboratories within quality control are very complicated to schedule due to the high product mix and diversified products tested with many different analysts and instruments. Thus, it requires a flexible planning system to change and improve the overall lab performance and increase efficiency. This thesis is a case study in collaboration with Fresenius Kabi AB and the quality control (QC) department in Uppsala. The QC department has an inflow of batches from the production department as well as from internal customers. Internal customers usually send batches that are part of stability studies or projects. These stability batches arrive at the QC department within irregular intervals and sometimes tightly adjacent, making the QC planning more complex, creating backlogs. Hence, the question in the study is formulated: ● How to improve a planning system and workflow in a quality control department? The current condition of batch inflow and how the planning system is managed today have to be understood to answer the question. Hence, the following sub-questions will be answered: ○ How is the current planning system at the quality control structured? ○ How is the inflow of stability batches at the department made more even andpredictable? This study aims to accomplish a practical planning system to prevent WIP, bottlenecks, and backlogs. The thesis is based on a qualitative method involving an inductive approach. The data collected mainly includes data from incoming batches, interviews, and literature studiesto gain multiple perspectives on the covered area. The study results showed that the internal customers were not satisfied with the current delivery times of QC. The common patterns identified are that internal customers want more contact and cooperation with the QC department. Furthermore, the result shows that the QC can handle the batches that arrive, but the planning system is not good enough. The proposed improvements to the current planning  system are mainly to change it to a longer-term planning system and introduce a standard log or planning system between the internal departments. Also, QC should reorganize the lab and schedule based on common analysis to accomplish a higher efficiency of the scheduling. Further recommendations include more transparency and precise planning between departments to improve the inflow of the stability batches. / Quality Control (QC) laboratorium är svåra att planera detta på grund den höga mängden och variationen av produkter. Det kräver således ett flexibelt planeringssystem för att förändra och förbättra prestandan och öka effektiviteten i laboratorier. Detta examensarbete är en fallstudie i samarbete med Fresenius Kabi AB och deras kvalitetsavdelningen i Uppsala. QC avdelningen har ett inflöde av batcher från produktionsavdelningen samt från de interna kunder. De interna kunderna skickar vanligtvis batcher som ingår i stabilitetsstudier eller projekt. Dessa stabilitets batchar inkommer till QC inom icke bestämda tidpunkter och ibland tätt inpå varandra, vilket försvårar planeringen inom QC vilket in sin tur skapar backloggar. Därav är frågeställningen i studien formulerad: ● Hur kan ett planeringssystem och arbetsflöde i ett kvalitetskontroll laboratoriumförbättras? För att kunna besvara denna frågeställning bör det aktuella planeringssystemet i avdelningen att undersökas. Därav kommer även dessa delfrågor att besvaras för att i denna studie: ● Hur är det nuvarande planeringssystemet strukturerat? ● Hur kan inflödet av stabilitets studier på avdelningen jämnas ut och bli mer förutsägbara? Syftet med denna studie är därav att effektivisera det nuvarande planeringssystem för att förhindra WIP, flaskhalsar och backlogs i QC avdelningen. Examensarbetet bygger på en kvalitativ metod med en induktiv forskningsansats. Den insamlade datan främst inkluderar data från inkommande batcher, intervjuer samt litteraturstudie för att få flera perspektiv av det undersökta ämnesområdet. Studiens resultat visade att samtliga interna kunder inte är nöjda med de nuvarande leveranstider som QC har. De gemensamma mönster som identifierats är att de interna kunderna önskar mer kontakt och samarbete med QC avdelningen. Vidare visar resultatet att QC bör ha kapaciteten som krävs för att kunna hanterade batcher som inkommer men att planeringen inte är tillräckligt bra. De förbättringsförslag som föreslås till det nuvarande planeringssystemet är främst att utveckla en mer långsiktig planering samt införa en gemensam logg. QC avdelningen på Fresenius Kabi bör även se över sin organisering och dela in grupper baserat på analyser och inte utrustning. Vidare rekommendationer inkluderar mer transparent och tydlig planering mellan avdelningarna.

Purpose: The purpose of this study is to identify and develop relevant keyperformance indicators within the warehouse operations in amanufacturing company, and how they can be used for control. Research question: In a manufacturing company, which are the most important KPIs forcontrolling and monitoring the warehouse operations, and how can thoseKPIs be developed?Methodology: This master thesis is based on a case study at a pharmaceutical companynamed Fresenius Kabi. A qualitative approach has been used whereprimary data was collected through 10 structured & semi structuredinterviews and through observations in the warehouses to understand thecurrent state. Secondary data was used in form of academic papers to seewhat previous research had to say about KPIs and operation & processmanagement. Internal documents were also used as a secondary source. Findings: Two key performance indicators have been developed, productivity andcost efficiency. A template has been designed to produce the KPIs. Thisstudy contributes to the understanding of how to develop KPIs that fits amanufacturing company´s warehouse operations and a recommendation onhow you could develop a system for producing the data.