For whom do we draw buildings? Why does contemporary architecture look the way it does?Why are certain aesthetics considered more valid than others? With this project, I propose Dirty Geometry: norm-bending design that could challenge conventions within the field of architecture. It is an investigation of concepts such as ugliness, beauty, architecture and the human body, interiority, femininity and ”bad taste”. The purpose is to, with the aid of parametric design processes, make Stockholm less boring and more dirty. Dirty Geometry is both the creative process sprung from one’s personal desires, and the resulting design. It aims to celebrate the weird, playful and colorful in an empowering way. This thesis project draws a lot of inspiration from camp aesthetics and drag culture, because of the way humour is used in a subversive way to question gender identities, power structures and norms.

It is my belief that theatre is the telling of stories, and that playwrighting is the creation of those stories. Regardless of the underlying motives (to make the audience think, to make them feel, to offend them or to draw them in,) the core of the theatre world is the storyline. Some critics write of the importance of audience effect and audience reception; after all, a performance can only be so named if at least one person is there to witness it. So much of audience effect is based the storyline itself - that structure of which is created by the power characters have over others. Theatre generalists learn of Aristotle's well-made play structure. Playwrights quickly learn to distinguish between protagonists and antagonists. Actors are routinely taught physicalizations of creating "status" onstage. A plotline is driven by the power that people, circumstances, and even fate exercise over protagonists. Most audience members naturally sympathize with the underdog or victim in a given storyline, and so the submissive or oppressed character becomes (largely) the most integral. By what process, then, is this sense of oppression created in a play? How can oppression/victimization be analyzed with regard to character development? With emerging criticism suggesting that the concept of character is dying, what portrayals of victim have we seen in the late 20th century? What framework can we use to fully understand this complex concept? What are we to see in the future, and how will the concept evolve? In my attempt to answer these questions, I first analyze the definition of "victim" and what categories of victimization exist - the victim of a crime, for example, or the victim of psychological oppression. "Victim" is a word with an extraordinarily complex definition, and so for the purposes of this study, I focus entirely on social victimization - that is, oppression or harm inflicted on a character by their peers or society. I focus on three major elements of this sort of victimization: harm inflicted on a character by another (not by their own actions), harm inflicted despite struggle or protest, and a power or authority endowed on the victimizer by the victim. After defining these elements, I analyze the literary methods by which playwrights can represent or create victimization - blurred lines of authority, expressive text, and the creation of emotion through visual and auditory means. Once the concept of victim is defined and a framework established for viewing it in the theatre, I analyze the victimization of one of American theatre's most famous sufferers - Eugene O'Neill's Yank in The Hairy Ape. To best contextualize this character, I explore the theories of theatre in this time period - reflections of social struggles, the concept of hierarchy, and clearly drawn class lines. I also position The Hairy Ape in its immediate historical and theoretical time period, to understand if O'Neill created a reflection on or of his contemporaries. Finally, I look at the concept of victim through the nonrealistic and nonlinear plays of the 20th century - how it has changed, evolved, or even (as Eleanor Fuchs may suggest) died. I found that my previously established framework for "making victim" has change dramatically to apply to contemporary nonlinear theatre pieces. Through this study, I have found that the lines of victimization and authority are as blurred today in nonrealistic and nonlinear theatre as they were in the seemingly "black and white" dramas of the 1920s and 30s. In my research, I have found the very beginnings of an extraordinarily complex definition of "victim".

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The moment-to-moment fluctuations in pain-evoked sensory and emotional qualities, and how the pain experience differs between sexes are not well understood. Therefore, this thesis sought to 1) characterise the temporal profiles of the most prominent noxious heat-evoked sensations, 2) characterise sex differences in these sensations, 3) evaluate the magnitude of sharp pain quality evoked in hairy and glabrous skin, and 4) determine the role of absolute stimulus temperatures on sex differences in pain adaptation and habituation. A broad-based heat pain model was developed for this study that incorporates a temporally-continuous assessment of multiple sensory and affective pain dimensions, including pain, burning, sharp, stinging, cutting, and annoyance evoked by two types (static, dynamic) of repeated prolonged noxious heat stimuli. The salient hypotheses were: 1) Burning sensations have a different temporal profile compared with sharp and other related qualities, 2) The temporal dynamics of heat pain intensity and annoyance differ between males and females, 3) Sex differences in heat pain are associated with specific pain qualities and specific types of skin, and 4) Moderate-high temperatures induce pain adaptation and habituation in females but not in males. The most prominent findings were 1) sharp, stinging and cutting sensations adapted when stimulus intensity was static, but burning sensations were evoked during static and dynamic stimulus phases, 2) pain and annoyance in women were greater than men during the dynamic phases of the first stimulus but less than men during static stimulus phases and on stimulus repetition, 3) the sex difference in pain adaptation occurred with percept-fixed stimulus intensities and with absolute stimulus temperatures, 4) the sex effects associated with dynamic stimuli occurred in hairy but not glabrous skin. These findings give new insights into the relationships between pain intensity, quality and affect and have strong implications for views on sex differences in pain sensitivity.

The moment-to-moment fluctuations in pain-evoked sensory and emotional qualities, and how the pain experience differs between sexes are not well understood. Therefore, this thesis sought to 1) characterise the temporal profiles of the most prominent noxious heat-evoked sensations, 2) characterise sex differences in these sensations, 3) evaluate the magnitude of sharp pain quality evoked in hairy and glabrous skin, and 4) determine the role of absolute stimulus temperatures on sex differences in pain adaptation and habituation. A broad-based heat pain model was developed for this study that incorporates a temporally-continuous assessment of multiple sensory and affective pain dimensions, including pain, burning, sharp, stinging, cutting, and annoyance evoked by two types (static, dynamic) of repeated prolonged noxious heat stimuli. The salient hypotheses were: 1) Burning sensations have a different temporal profile compared with sharp and other related qualities, 2) The temporal dynamics of heat pain intensity and annoyance differ between males and females, 3) Sex differences in heat pain are associated with specific pain qualities and specific types of skin, and 4) Moderate-high temperatures induce pain adaptation and habituation in females but not in males. The most prominent findings were 1) sharp, stinging and cutting sensations adapted when stimulus intensity was static, but burning sensations were evoked during static and dynamic stimulus phases, 2) pain and annoyance in women were greater than men during the dynamic phases of the first stimulus but less than men during static stimulus phases and on stimulus repetition, 3) the sex difference in pain adaptation occurred with percept-fixed stimulus intensities and with absolute stimulus temperatures, 4) the sex effects associated with dynamic stimuli occurred in hairy but not glabrous skin. These findings give new insights into the relationships between pain intensity, quality and affect and have strong implications for views on sex differences in pain sensitivity.

Grâce à la présence et à l’instrumentalisation de la Mare de Déu, l’abbaye et le massif de Montserrat sont devenus, au fil des siècles, un symbole religieux et un bastion du christianisme, puis les gardiens des traditions, de la culture et de l’identité catalanes. Le mythe fondateur religieux, lié à la Vierge de Montserrat, est associé au mythe fondateur de la Catalogne, lié au comte de Barcelone Guifré le Velu, de sorte que religion et identité nationale sont étroitement imbriquées dès la fin du Moyen Âge. Beaucoup d’autres légendes sont élaborées à cette époque, mais la relation entre les Catalans et la Mare de Déu de Montserrat prend une orientation particulière et s’exerce dans un cadre à part.L’universalité de la pensée mythique permet une instrumentalisation politico-religieuse de l’image mariale tout au long de l'histoire de la Catalogne, jusqu’à aujourd’hui. Le XIXe siècle marque une étape majeure dans l’instrumentalisation de la Moreneta et sa liaison avec le sentiment identitaire. Le massif de Montserrat devient le symbole de la patrie catalane et la Vierge de Montserrat se transforme en Vierge de la Patrie. Le régime franquiste signifie une rupture profonde. La Moreneta, dans un premier temps, protège l’action de suppléance intellectuelle et culturelle accomplie par les Bénédictins de Montserrat, puis l’engagement politique devient total. Avec l’arrivée de la démocratie, la Catalogne se réapproprie son passé, et un nouveau rôle se dessine pour la Mare de Déu de Montserrat. / Thanks to the presence and implementation of the Mare de Déu, the abbey and the mountain of Montserrat became, in the course of the centuries, a religious symbol and a bastion of christianity, and, later on, the guardians of the catalan traditions, culture and identity. The religious founding myth, linked to Montserrat Virgin, is associated with Barcelona Count Guifré le Velu, so that religion and national identity have remained closely interlinked since the end of the Middle Ages. Numerous other legends were created at the same time, but the relationship between Catalan people and the Mare de Déu of Montserrat takes a special orientation and grows in a specific place.The universality of the myths enables a political and religious implementation of the marian image throughout the history of Catalonia, until nowadays. The XIXe century marks a major step in the implementation of the Moreneta and Her connection with the sense of identity. The Montserrat mountain becomes the symbol of the Catalan mother country and the Virgin of Montserrat is transformed into the Virgin of the mother country. The pro-Franco regime meant a deep change. At first, the Moreneta protectd the intellectual and cultural substitution carried out by the Montserrat Benedictines, then their political commitment became total. With the arrival of democracy, Catalonia has been recovering its past, and a new role has been emerging for the Mare de Déu of Montserrat.

“‘Oh, Awful Power’: Energy and Modernity in African American Literature” analyzes the social and cultural meaning of energy through an examination of African American literature from the first half of the twentieth century—the era of both King Coal and Jim Crow. Situating African Americans as both makers and subjects of the history of modern energy, I argue that black writers from this period understood energy as a material substrate which moves continually across boundaries of body, space, machine, and state. Reconsidering the surface of metaphor which has masked the significant material presence of energy in African American literature--the ubiquity of the racialized descriptor of “coal-black” skin, to take one example—I show how black writers have theorized energy as a simultaneously material, social, and cultural web, at once a medium of control and a conduit for emancipation. African American literature emphasizes how intensely energy impacts not only those who come into contact with its material instantiation as fuel—convict miners, building superintendents—but also those at something of a physical remove, through the more ambient experiences of heat, landscape, and light. By attending to a variety of experiences of energy and the nuances of their literary depiction, “‘Oh, Awful Power’” shows how twentieth-century African American literature not only anticipates some of the later insights of the field now referred to as the Energy Humanities but also illustrates some ways of rethinking the limits of that discourse on interactions between energy, labor, and modernity, especially as they relate to problems of race. These insights are made especially visible, I argue, by way of experiments with literary form, particularly through play with the expectations, limitations, and affordances of genre. I identify three particular generic formations which prove vital to the African American theorization of modern energy: the picturesque, tragedy, and naturalism. In my first chapter, I examine a 1986 novel by West Virginia-born novelist and politician J. McHenry Jones, entitled Hearts of Gold, which features the rare portrayal of black life in a convict coal mine at its narrative core. The feverish episode in the mine stands out against the otherwise genteel narrative of light-skinned striving and respectability, which aligns closely with Washingtonian ideologies of progress and the aesthetic sensibilities of the picturesque. In this depiction of the convict mine, Jones both poses a challenge to the social and political ideologies which subtend the picturesque, and draws a novel link between the rise of coal and the persistence of slavery in the form of the convict lease system. Chapter two extends Jones’ critique of the racial politics of coal mining through an examination of Shirley Graham’s Dust to Earth, a play briefly produced in 1941 which depicts the interracial conflicts that arise after a deadly collapse at a coal mine in Illinois. I argue that the play represents the fulfillment of Graham’s earlier project of rewriting Eugene O’Neill’s The Hairy Ape for an all-black cast—a project that O’Neill himself swiftly vetoed. Examining Dust to Earth’s intertwined plots of descent and sabotage, I show how the play exploits the generic conventions of tragedy in order to reconfigure familiar narratives of racial domination to fit the distinctly modern space of the coal mine. My third chapter reads the presence of two relatively “minor” forms of energy—hydroelectricity and solar power—in two novels by George Schuyler and W.E.B. Du Bois, Dark Princess (1928) and Black Empire (193638). In each of these texts, energy is written into the narrative as a powerful force, capable of affecting social and political life on a global scale. I argue that Du Bois’ romance is better understood as an experiment in naturalism, and that through conceiving of the body as a “human motor” Du Bois is able to form a critique of progressive era hydroelectric projects as aspects of an international war for colonial control. For Schuyler, on the other hand, solar power is figured as a potentially revolutionary form of energy that, despite its roots in a recent history of imperial expansion, nonetheless carries some promise once wrested from the control of the nation-state. In my final chapter, I interpret Ann Petry’s 1946 naturalist novel The Street as a drama of thermal management—a narrative in which the cultural politics of energy are refracted primarily through various characters’ bodily experiences of temperature. I argue that the protagonist’s struggle to maintain homeostasis represents an embodied critique of the often-elided racial politics of domestic heat. Finally, with the literary history of the furnace room as a backdrop, I argue that Petry’s depiction of the space foregrounds its paradoxical status as both a crucible of atavistic degeneration and a fount of humanist inspiration.

Magister Chirurgiae Dentium - MChD / Purpose: To assess the oral health status of 4-15-year-old schoolchildren in the Western Region of the Eastern Cape Province, by determining the prevalence of dental caries, periodontal disease, dental fluorosis, malocclusion and oral mucosal lesions and to create baseline data for planning oral health services in this region. Materials and Methods: The prevalent analytic survey was undertaken on 822 schoolchildren between the ages of 4-15 years in 27 different schools. The sample size selected for this region by the Department of Statistics, University of Pretoria, for the National Oral Health Survey of 1999/2000 was used. The data on 209, 210, 209 and 194 scholars in the 4-5, 6, 12 and 15-year-old age groups respectively were collected. The World Health Organization's (1997) criteria were used to determine the prevalence of caries, periodontal treatment needs, the dental fluorosis, malocclusion and prevalence of oral mucosal lesions. Six calibrated and trained examiners recorded the data on a survey form. The WHO survey forms were used for data collection. The data were analysed and processed by the author on Microsoft Excel 2000. Results: The sample size consisted of 1.35 % Asian, 51.89 % Black, 26.07 % Coloured and 20.06 % White scholars. Nearly equal amounts of males (48.3 %) and females (51.7%) were examined. The dental caries prevalence in the primary dentition of 4-5-year-olds with an average age of 4.43 years was 40.67%, with a mean dmft of 3,56. The dental caries prevalence in the permanent dentition of6-, 12- and 15-year-oldage groups was 67.62%, 46.05% and 67.92% respectively. The mean DMFT for 6-, 12- and 15 year olds were 0.05, 1.19 and 2.02 respectively. Gender differences and differences in prevalence of dental caries between the populations groups were recorded. The Coloured children experienced the highest dental caries prevalence. In the 4-5- and 15-year-old groups the males were affected more than the females by dental caries. Prevalent differences were recorded between rural and urban areas in the same population group. The prevalence of periodontal disease in 373, 12-15-year-olds was 79.09%. Only 4.02 % were in need of dental hygiene instructions and polishing. Dental education, dental hygiene instructions, dental scaling and polishing were needed by 75.07% of the children. Dental fluorosis prevalence in 450, 6-15-year-olds was 13.03%. Dental fluorosis did not affect 86.97% of the scholars; 10.63% had mild fluorosis and 2.05% was severely affected. The mean fluoride concentration in the drinking water in this region were 1.07 mgIL, ranging between 0.3-3 mgIL. Definite malocclusion was recorded in only 0.48% of the 12-year-old group, whom needed elective treatment. In the 12-year-olds, 99.52% needed no or slight treatment for no or minor malocclusions. The majority of children had no oral mucosal lesions (91.55%). The prevalence of oral mucosal lesions was 8.5% in this survey. The most frequent conditions were traumatic lesions (1.96%), dento-alveolar abscess (1.22%) and herpes labialis (1.22%). The intra-examiner reliability for caries, dental fluorosis, periodontal treatment needs and prevalence of malocclusions was 97.66%, 100%, 88.89% and 86.67% respectively. The inter-examiner reliability was 98.75%, 98.34%, 100%, 100% and 100% respectively for the five examiners. Conclusion: This survey indicated a higher prevalence of dental caries in the primary dentition (63.48%), than the permanent dentition (41.3%). The mean dmft was 3.65 and the DMFT 1.2, which indicated a low mean caries experience for these children. The WHO goal for the year 2000 for the 6-year-olds of 50% being caries free has not reached for only 32.56% were caries free. The mean DMFT of 1.2 for 12-year-olds in this survey is below the WHO goal of a mean DMFT of 1.5 or less. The lack of available preventative service provision, were ) indicated by the low percentage of fissure sealants (2.8%). The need for dental treatment was highlighted by the need mostly for one-surface restorations. Preventative treatment, two-surface fillings and extractions were also needed. Periodontal disease was a major public oral health concern for this region for a prevalence of 79.09% was recorded for the 12-15-year-olds. The majority of the children affected by periodontal disease (75.07%) were in need of professional cleaning and calculus removal. The prevalence of dental fluorosis was 8.2%, 19.87% and 13.05% for 6-, 12- and IS-year age groups respectively. The prevalence of malocclusion was 0.48% for the 12-year-old group. The prevalence of oral mucosa lesions was 8.5% for 4-15-year-old schoolchildren. Therefore, the conclusion can be made that dental fluorosis; malocclusions and oral mucosal lesions were no public concern in this region. The major public oral health concerns were dental caries in the primary dentition and periodontal disease in all age groups. Recommendations: Dental services in this region should be directed towards prevention of dental caries in the primary dentition and periodontal disease in all age groups. The focus of dental services should be primarily on preventative programs and treatments. The public dental treatments needs indicated in this survey, namely scaling and polishing, restorations and extractions, consists of the primary health care package delivery. Currently, no evaluation tool exists to monitor the efficiency of oral health programs, no baseline data for the Province exists. Therefore, the urgent need for dental research and oral health service planning and delivery are recommended.

Ce travail est axé sur l’amélioration des propriétés de biospécificité de sondes polymères fluorescentes, d’architectures contrôlées synthétisées par polymérisation RAFT, pour deux applications principales : le ciblage de tumeurs cancéreuses in vivo et le marquage de protéines pour des études in cellulo. Pour une imagerie ciblée de l’angiogénèse tumorale in vivo, des systèmes de ciblage multivalents à deux niveaux ont été élaborés en combinant à la fois i) des polymères bien contrôlés synthétisés par polymérisation RAFT et par le procédé PISA, ii) des clusters peptidiques tétravalents présentant une forte affinité pour les intégrines αvβ3 et iii) des fluorophores émettant dans le rouge lointain/proche-infrarouge pour un suivi in vitro et in vivo par microscopie optique. Deux types de sondes ont été synthétisés, des conjugués linéaires et des nanoparticules chevelues. La présentation multivalente du cluster peptidique permet d’augmenter considérablement l’affinité pour les intégrines αvβ3. Les premières évaluations biologiques indiquent une internalisation cellulaire des sondes polymères médiée par les clusters peptidiques ainsi qu’un marquage sélectif des cellules sur-exprimant les intégrines αVβ3. Pour le marquage de protéines, deux stratégies ont été explorées : le marquage de protéines natives par couplage covalent de sondes ω-fonctionnelles et le marquage de protéines recombinantes par des sondes porteuses d’un ligand spécifique. Pour la première stratégie, une fonction ester activé a été introduite en extrémité ω de sondes polymères par chimie thiol-ène pour marquer les résidus lysines des protéines natives. Cette approche a abouti à un poly-marquage difficile à contrôler mais offrant une brillance élevée. Pour la seconde stratégie, un groupement acide nitrilotriacétique (NTA) a été introduit en extrémité α des sondes polymères afin de marquer spécifiquement les protéines taguées Histidines. Cette approche a permis un marquage efficace de différentes protéines et permet de contrôler précisément le nombre de sondes par protéine ainsi que leur site de fixation sur la protéine. Finalement, suite à ces travaux, une nouvelle stratégie de synthèse de polymères séquencés par addition successive de monomères hétéro-bifonctionnels en utilisant des réactions chimiques très efficaces, sélectives et orthogonales a été proposée et validée. / This work is focused on improving the biospecificity properties of fluorescent polymer probes, with controlled architectures, for two main applications: the in vivo targeting of cancer tumors and the labeling of proteins for in cellulo studies. For a targeted imaging of tumor angiogenesis in vivo, targeting systems presenting two levels of multivalency were developed by combining both i) well-controlled polymers synthesized by RAFT polymerization and the PISA process, ii) peptide tetravalent clusters exhibiting a high affinity for the αvβ3 integrins and iii) fluorophores emitting in the far red / near-infrared for a monitoring in vitro and in vivo by optical microscopy. Two types of probes were synthesized, linear conjugates and hairy nanoparticles. Multivalent presentation of the peptide cluster induced a significant increase of the affinity for αvβ3 integrins. The first biological evaluations also indicated an efficient cellular internalization of polymer probes mediated by the peptide clusters and a selective labeling of cells over-expressing αvβ3 integrins. For protein labeling, two strategies were explored: the labeling of native proteins by covalent coupling of ω-functional polymer probes and the labeling of recombinant proteins by probes bearing a specific ligand at one chain-end. For the first strategy, an activated ester function was introduced at the ω-end of polymer probes by thiol-ene chemistry to label the lysine residues of native proteins. This approach resulted in a poly-labeling, difficult to control but providing highly bright bioconjugates. For the second strategy, a nitrilotriacetic acid group (NTA) was introduced at the α-end of polymers probes to specifically label Histidine tagged proteins. This approach enabled an efficient labeling of different proteins with a more precise control of the number of probes per protein and of the binding site. Finally, following this work, a new synthetic strategy of sequenced polymers by successive addition of hetero-bifunctional monomers using highly efficient, selective and orthogonal chemical reactions was proposed and validated.