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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
81

Die representasie van Kwasi/Aquasi : 'n ondersoek na die voortsetting al dan nie van die koloniale diskoers in De zwarte met het witte hart deur Arthur Japin

Faasen, Petro 03 1900 (has links)
Thesis (MA)--Stellenbosch University, 2003. / ENGLISH ABSTRACT: The term 'representation' is often used to refer to the possibility of a link between literature and reality. The word also suggests the reiteration of an event and is used in literary studies to indicate that a representation should be read as the author's interpretation of events and thus as a mediated rendition thereof. This study focuses on the representation of a black character who lived in the 19th Century by a white author from the zo" Century, Arthur Japin, in his novel, De zwarte met het witte hart (1997). This novel, based on historical events, is a rendering of the lives of two Ashanti princes who were taken to the Netherlands in 1837 as guarantee to an agreement between the king of the Ashanti and the Netherlands. This study therefore looks at the way in which Japin interpreted and represented the available information in his novel. This study furthermore focuses on ways in which this novel, written in what may be termed a postcolonial era could be read as a continuation of the colonial discourse in the 21st Century. This is demonstrated by identifying and examining the characteristics of colonial discourse, postcolonial discourse, the historic novel and the didactic novel, as well as ways in which these genres deal with representation. The study refers to the work of literary and social theoreticians such as Edward Said, Frantz Fanon, Homi Bhabha, Gayatri Spivak, Linda Hutcheon and Maaike Meijer. The study indicates that this novel can partially be read as a continuation of the colonial discourse. The results of this study also indicates that an uncritical reading of the novel De zwarte met het witte hart could lead to a continuation of the colonial discourse in the 21st Century. The role and responsibility of the reader in the interpretation and the subversion of the colonial discourse could therefore be further investigated. / AFRIKAANSE OPSOMMING: Die term 'representasie' word dikwels gebruik om die moontlikheid van 'n verband tussen die letterkunde en die werklikheid aan te dui. Die woord suggereer die herhaling van 'n gegewe en word in die letterkunde gebruik om aan te dui dat die representasie wat gelees word, die outeur se interpretasie en dus bemiddelde weergawe van gebeure is. Hierdie ondersoek fokus op die representasie van 'n swart hoofkarakter uit die 19de eeu deur 'n blanke outeur in die 20ste eeu soos dit in die roman, De zwarte met het witte hart (1997) deur Arthur Japin, weergegee word. Hierdie roman, gebaseer op historiese gegewens, handeloor die lewens van twee Ashanti prinse wat in 1837 as onderpand vir 'n ooreenkoms tussen Nederland en die Ashantynse koning na Nederland geneem is en die gevolge wat dit vir hulle ingehou het. Daar word dus in dié ondersoek gekyk na die manier waarop Japin die gegewens tot sy beskikking geïnterpreteer en in die roman weergegee het. Verder fokus die ondersoek op die manier waarop hierdie roman, geskryf in wat as 'n postkoloniale era gesien kan word, moontlik as 'n voortsetting van die koloniale diskoers in die 21ste eeu gelees kan word. Dit word gedoen deur kenmerke van die koloniale diskoers, die postkoloniale diskoers, die historiese roman en die tendensroman te identifiseer en ondersoek, saam met die wyses waarop hierdie genres met representasie omgaan. Daar word verwys na die werk van letterkundige en sosiale teoretici soos Edward Said, Frantz Fanon, Homi Bhabha, Gayatri Spivak, Linda Hutcheon en Maaike Meijer. Uit die ondersoek blyk dat hierdie roman gedeeltelik as 'n voortsetting van die koloniale diskoers gelees kan word. Die resultate van hierdie ondersoek dui ook aan dat 'n onkritiese lees van die roman De zwarte met het witte hart kan lei tot die voortsetting van die koloniale diskoers in die 21ste eeu. Die rol en die verantwoordelikheid van die leser in die interpretasie en ondermyning van die koloniale diskoers kan dus verder ondersoek word.
82

The pamphlet that woke a nation

Sterk, John 10 April 2008 (has links)
No description available.
83

Aplicação do óleo de buriti no desenvolvimento de emulsões e estudo da citotoxicidade e potencial foto-protetor em cultivo celular / Application of Buriti oil (Mauritia flexuosa) on emulsions development and cytotoxic and photoprotector potential evaluation in cell culture.

Zanatta, Cinthia Fernanda 07 May 2008 (has links)
Nos últimos anos intensificou-se o estudo sobre sistemas criados para veicular princípios ativos, como nanoemulsões, dispersões contendo cristais líquidos e emulsões múltiplas, bem como o emprego de matérias-primas da biodiversidade brasileira na produção destes sistemas, a exemplo dos óleos de andiroba, copaíba, urucum e buriti, cuja fruta amazônica é rica em micro-nutrientes com propriedades anti-oxidante, hidratante e fotoprotetora. Durante o desenvolvimento de novas formulações cosméticas, o potencial de irritação dérmica deve ser investigado antes que o produto seja disponibilizado ao consumidor, a fim de identificar compostos que possam causar reações adversas na pele. O objetivo deste trabalho foi avaliar cientificamente o emprego do óleo de buriti na obtenção de emulsões contendo cristais líquidos, nanoemulsões e emulsões múltiplas estáveis e estudar o possível potencial citotóxico e fotoprotetor destas formulações em culturas de células epidérmicas (fibroblastos e queratinócitos), bem como o potencial irritante em modelo organotípico (HET-CAM). Foi estabelecido como valor de EHL crítico igual a 7,25 e selecionados dois pares de tensoativos (Steareth-2 associado aos Ceteareth- 5 e Ceteareth-20) para produção das macroemulsões contendo cristal líquido pela técnica do diagrama ternário. Os testes preliminares em centrifuga, estresse térmico, microscopia, potencial zeta e o estudo do comportamento reológico permitiram a seleção de uma emulsão de cada diagrama para continuar o estudo, as quais foram submetidas aos testes de estabilidade acelerada. As formulações F29D1 e F51D2 com e sem vitamina E não apresentaram modificações no comportamento reológico, pH e estabilidade física, após serem submetidas às condições de estresse. O método de emulsificação em etapa única se mostrou eficiente na produção de emulsões múltiplas estáveis à centrifugação e estresse térmico, com óleo de buriti e monooleato de sorbitano e PEG-40 castor oil como sistema tensoativo. O estudo de EHL crítico da emulsão múltipla mostrou maior estabilidade do sistema no valor de EHL=9,0. Uma modificação no processo de emulsificação da emulsão múltipla permitiu a obtenção de nanoemulsões estáveis por PIT, cujas temperaturas de inversão de fases foram de 89, 91 e 93°C, para os valores de EHL 9,0; 9,5 e 10,0 respectivamente. Os resultados dos ensaios de citotoxicidade mostraram que as emulsões formuladas com óleo de buriti e tensoativos comerciais se mostraram não irritantes à pele devido aos escassos efeitos citotóxicos que provocaram às monocamadas de fibroblastos 3T3 e queratinócitos HaCat, sendo que a adição de vitamina E chegou a aumentar a viabilidade celular em alguns casos. As emulsões contendo álcoois graxos etoxilados como sistema tensoativo, se mostraram mais fototóxicas às células quando comparadas as que continham outra classe de tensoativos não iônicos, sendo que todas se mostraram mais fototóxicas quando foram aplicadas em condições de pré-tratamento. Os ensaios também demonstraram que os fibroblastos 3T3 foram mais sensíveis que os queratinócitos HaCat ao efeito da radiação quando tratados com os produtos. O ensaio em membrana corioalantóide auxiliou na identificação dos compostos irritantes e confirmou os resultados obtidos nos ensaios de citotoxicidade e associados podem ser considerados uma ferramenta importante na substituição de animais para avaliação do potencial irritante de produtos cosméticos e farmacêuticos. / In the past few years, more attention has been given to delivery systems, like nanoemulsions, emulsions containing liquid crystals and multiple emulsions, as well as the employment of new raw materials from the Brazilians biodiversity in their production, such as Andiroba, Copaíba, Urucum and Buriti oils. The Buriti is an Amazonian fruit rich in micro nutrients, with antioxidants and photoprotector properties. During the development of new cosmetic formulations, the skin irritation potential must be investigated in order to identify chemicals which might induce adverse skin reactions, previously to human exposition to such substances. The aim of this work was to evaluate the employment of Buriti oil in the production of stable nanoemulsions, emulsions containing liquid crystals and multiple emulsions; and study their cytotoxic and photoprotector potential in epidermal cell culture and irritancy potential in organotypic model (HET-CAM). Two surfactant systems were chosen (Steareth-2 associated to Ceteareth-5 and Ceteareth-20) at the critical HLB value of 7.25 to produce the macroemulsions containing liquid crystals using the ternary diagram technique. Preliminary stability tests such as centrifugation, thermal stress, microscopic analysis, zeta potential and rheological behavior were used to choose one emulsion from each diagram. Subsequently, those emulsions were submitted to accelerated stability tests. The formulations F29D1 and F51D2, containing or not Vitamin E, did not present modifications in their physical stability, pH and rheological behavior after being exposed to the stress conditions. The emulsification method by one step demonstrated to be an efficient methodology to attain multiple emulsions containing Buriti oil, Sorbitan monooleato and PEG-40 castor oil as surfactant system. This system remained stable even after centrifugation and thermal stress. At a critical HBL of 9.0, the multiple emulsions showed major stability. A single modification performed on the emulsification method of the multiple emulsion allowed the production of stable nanoemulsions by PIT method. The phase inversion temperatures were identified as 89, 91 e 93°C, for the emulsions at HLB values equal to 9.0, 9.5 and 10.0, respectively. The results of the cytotoxicity assays showed that the emulsions containing Buriti oil and commercial surfactants are non-irritant to skin due to their low cytotoxic effects in the 3T3 and HaCat cell monolayers. The addition of vitamin E not only decreased the toxicity of the products, but also increased the cellular viability. The emulsions containing ethoxylated fatty alcohol as surfactant systems showed to be more phototoxic to the cells than those prepared with another class of non ionic surfactant. All the emulsions demonstrated to be more phototoxic when applied on the cells during pre-treatment condition, moreover the 3T3 fibroblasts demonstrated to be more sensitive to the majority of products than the HaCat, after exposed to UV radiation. The hens egg test-chorioallantoic membrane has collaborated the identification of irritant chemicals and confirmed the results obtained on the cytotoxicity assays. Those assays associated should be considered a valuable tool to evaluate irritancy potential of cosmetics and pharmaceutical products.
84

Développement, caractérisation et modélisation d'interfaces pour cellules solaires à haut rendement à base d'hétérojonctions de silicium

Varache, Renaud 20 November 2012 (has links) (PDF)
L'interface entre le silicium amorphe (a-Si:H) et le silicium cristallin (c-Si) est un constituent clés de cellules solaires à haut rendement reposant sur des procédés à basse température. Trois propriétés de l'interface déterminent le rendement des cellules solaires à hétérojonction de silicium: les décalages de bandes entre a-Si:H et c-Si, les défauts d'interface et la courbure de bande dans c-Si. Ces trois aspects sont traités dans ces travaux de thèse.Dans un premier un temps, un calcul analytique de la courbure de bande dans c-Si est développé. Il repose sur l'approximation d'une densité d'état (DE) constante dans la bande interdite de a-Si:H. L'influence des principaux paramètres de la structure sur la courbure de bande est étudiée : décalage de bande, densité d'état dans a-Si:H, défaut d'interface, etc. La présence d'un effet de confinement quantique est discutée. Grâce à une comparaison entre ces calculs et des mesures de conductance planaire en fonction de la température sur des structures (p)a-Si:H/(n)c-Si et (n)a-Si:H/(p)c-Si, les décalages de bande de valence et de conduction ont pu être estimés à 0.36 eV et 0.15 eV respectivement. En outre, il est montré que le décalage de la bande de valence est indépendant de la température, alors que le décalage de la bande de conduction suit les évolutions des bandes interdites de c-Si et a-Si:H. Ces mesures tendent à prouver que le 'branch point' dans a-Si:H est indépendant du dopage.Ensuite, les calculs analytiques sont approfondis pour prendre en compte différents aspects de la structure complète incorporée dans les cellules : contact avec un oxyde transparent conducteur, présence d'une couche de a-Si:H non-dopée à l'interface. A l'aide de simulations numériques et à la lumière de mesures de conductance planaire conjuguées à des mesures de la qualité de passivation de l'interface, des pistes pour optimiser les cellules à hétérojonction sont commentées. En particulier, il est montré qu'un optimum doit être trouvé entre une bonne passivation et une courbure de bande suffisante. Ceci peut être accompli par un réglage fin des propriétés de la couche tampon (épaisseur, dopage), du contact (travail de sortie élevé) et de l'émetteur (p)a-Si:H (densité de défauts et épaisseur). En particulier, un émetteur avec une DE importante conduit paradoxalement à de meilleures performances.Enfin, un nouveau type d'interface a été développé. La surface de c-Si a été oxydée volontairement dans de l'eau pure dé-ionisée à 80 °C avant le dépôt de (p)a-Si:H afin d'obtenir une structure (p)a-Si:H/SiO2/(n)c-Si. A l'aide d'un modèle de courant par effet tunnel implémenté dans le logiciel de simulation numérique AFORS-HET, l'effet d'une couche à grande bande interdite (comme c'est le cas pour SiO2) sur les performances de cellules est étudié : le facteur de forme et le courant de court-circuit sont extrêmement réduits. En revanche, une couche de SiO2 n'a que peu d'impact sur les propriétés optiques de la structure. Expérimentalement, les échantillons réalisés montrent une qualité de passivation à mi-chemin entre le cas sans couche tampon et le cas avec (i)a-Si:H : ceci est expliqué par la présence d'une charge fixe négative dans l'oxyde. La courbure de bande dans c-Si est moins affectée par la présence d'une couche d'oxyde que d'une couche de (i)a-Si:H. Les cellules solaires réalisées démontrent que le concept a le potentiel d'aboutir à de hauts rendements : sur des structures non-optimisées, une tension de court-circuit supérieure à 650 mV a été démontrée, alors que l'oxyde ne semble pas limiter le transport de charge.
85

Aplicação do óleo de buriti no desenvolvimento de emulsões e estudo da citotoxicidade e potencial foto-protetor em cultivo celular / Application of Buriti oil (Mauritia flexuosa) on emulsions development and cytotoxic and photoprotector potential evaluation in cell culture.

Cinthia Fernanda Zanatta 07 May 2008 (has links)
Nos últimos anos intensificou-se o estudo sobre sistemas criados para veicular princípios ativos, como nanoemulsões, dispersões contendo cristais líquidos e emulsões múltiplas, bem como o emprego de matérias-primas da biodiversidade brasileira na produção destes sistemas, a exemplo dos óleos de andiroba, copaíba, urucum e buriti, cuja fruta amazônica é rica em micro-nutrientes com propriedades anti-oxidante, hidratante e fotoprotetora. Durante o desenvolvimento de novas formulações cosméticas, o potencial de irritação dérmica deve ser investigado antes que o produto seja disponibilizado ao consumidor, a fim de identificar compostos que possam causar reações adversas na pele. O objetivo deste trabalho foi avaliar cientificamente o emprego do óleo de buriti na obtenção de emulsões contendo cristais líquidos, nanoemulsões e emulsões múltiplas estáveis e estudar o possível potencial citotóxico e fotoprotetor destas formulações em culturas de células epidérmicas (fibroblastos e queratinócitos), bem como o potencial irritante em modelo organotípico (HET-CAM). Foi estabelecido como valor de EHL crítico igual a 7,25 e selecionados dois pares de tensoativos (Steareth-2 associado aos Ceteareth- 5 e Ceteareth-20) para produção das macroemulsões contendo cristal líquido pela técnica do diagrama ternário. Os testes preliminares em centrifuga, estresse térmico, microscopia, potencial zeta e o estudo do comportamento reológico permitiram a seleção de uma emulsão de cada diagrama para continuar o estudo, as quais foram submetidas aos testes de estabilidade acelerada. As formulações F29D1 e F51D2 com e sem vitamina E não apresentaram modificações no comportamento reológico, pH e estabilidade física, após serem submetidas às condições de estresse. O método de emulsificação em etapa única se mostrou eficiente na produção de emulsões múltiplas estáveis à centrifugação e estresse térmico, com óleo de buriti e monooleato de sorbitano e PEG-40 castor oil como sistema tensoativo. O estudo de EHL crítico da emulsão múltipla mostrou maior estabilidade do sistema no valor de EHL=9,0. Uma modificação no processo de emulsificação da emulsão múltipla permitiu a obtenção de nanoemulsões estáveis por PIT, cujas temperaturas de inversão de fases foram de 89, 91 e 93°C, para os valores de EHL 9,0; 9,5 e 10,0 respectivamente. Os resultados dos ensaios de citotoxicidade mostraram que as emulsões formuladas com óleo de buriti e tensoativos comerciais se mostraram não irritantes à pele devido aos escassos efeitos citotóxicos que provocaram às monocamadas de fibroblastos 3T3 e queratinócitos HaCat, sendo que a adição de vitamina E chegou a aumentar a viabilidade celular em alguns casos. As emulsões contendo álcoois graxos etoxilados como sistema tensoativo, se mostraram mais fototóxicas às células quando comparadas as que continham outra classe de tensoativos não iônicos, sendo que todas se mostraram mais fototóxicas quando foram aplicadas em condições de pré-tratamento. Os ensaios também demonstraram que os fibroblastos 3T3 foram mais sensíveis que os queratinócitos HaCat ao efeito da radiação quando tratados com os produtos. O ensaio em membrana corioalantóide auxiliou na identificação dos compostos irritantes e confirmou os resultados obtidos nos ensaios de citotoxicidade e associados podem ser considerados uma ferramenta importante na substituição de animais para avaliação do potencial irritante de produtos cosméticos e farmacêuticos. / In the past few years, more attention has been given to delivery systems, like nanoemulsions, emulsions containing liquid crystals and multiple emulsions, as well as the employment of new raw materials from the Brazilians biodiversity in their production, such as Andiroba, Copaíba, Urucum and Buriti oils. The Buriti is an Amazonian fruit rich in micro nutrients, with antioxidants and photoprotector properties. During the development of new cosmetic formulations, the skin irritation potential must be investigated in order to identify chemicals which might induce adverse skin reactions, previously to human exposition to such substances. The aim of this work was to evaluate the employment of Buriti oil in the production of stable nanoemulsions, emulsions containing liquid crystals and multiple emulsions; and study their cytotoxic and photoprotector potential in epidermal cell culture and irritancy potential in organotypic model (HET-CAM). Two surfactant systems were chosen (Steareth-2 associated to Ceteareth-5 and Ceteareth-20) at the critical HLB value of 7.25 to produce the macroemulsions containing liquid crystals using the ternary diagram technique. Preliminary stability tests such as centrifugation, thermal stress, microscopic analysis, zeta potential and rheological behavior were used to choose one emulsion from each diagram. Subsequently, those emulsions were submitted to accelerated stability tests. The formulations F29D1 and F51D2, containing or not Vitamin E, did not present modifications in their physical stability, pH and rheological behavior after being exposed to the stress conditions. The emulsification method by one step demonstrated to be an efficient methodology to attain multiple emulsions containing Buriti oil, Sorbitan monooleato and PEG-40 castor oil as surfactant system. This system remained stable even after centrifugation and thermal stress. At a critical HBL of 9.0, the multiple emulsions showed major stability. A single modification performed on the emulsification method of the multiple emulsion allowed the production of stable nanoemulsions by PIT method. The phase inversion temperatures were identified as 89, 91 e 93°C, for the emulsions at HLB values equal to 9.0, 9.5 and 10.0, respectively. The results of the cytotoxicity assays showed that the emulsions containing Buriti oil and commercial surfactants are non-irritant to skin due to their low cytotoxic effects in the 3T3 and HaCat cell monolayers. The addition of vitamin E not only decreased the toxicity of the products, but also increased the cellular viability. The emulsions containing ethoxylated fatty alcohol as surfactant systems showed to be more phototoxic to the cells than those prepared with another class of non ionic surfactant. All the emulsions demonstrated to be more phototoxic when applied on the cells during pre-treatment condition, moreover the 3T3 fibroblasts demonstrated to be more sensitive to the majority of products than the HaCat, after exposed to UV radiation. The hens egg test-chorioallantoic membrane has collaborated the identification of irritant chemicals and confirmed the results obtained on the cytotoxicity assays. Those assays associated should be considered a valuable tool to evaluate irritancy potential of cosmetics and pharmaceutical products.
86

Hur påverkas operativa stridsfordonstransporter av olika grader av autonomi : En värdering av den militära nyttan / How does degree of autonomy affect the transportation of combat vehicles? : An analysis of the military utility

Liivrand, Daniel January 2020 (has links)
Helt självkörande fordon är inte längre en utopi eller något som man ser på film. Redan idag finns fullt fungerande prototyper och flera tillverkare påstår sig ha fullt självkörande fordon redan on några år. Autonomi bedöms civilt kunna ge upphov till flera resurseffektiviseringar inom vägtransportområdet. En kapacitetsökning av förmågan till förbandstransporter av stridsfordonsförband, samt en ökning av uthållighet, transportförmåga och tillgänglighet är faktorer som Försvarsmaktens perspektivstudie (2018) och Försvarsberedningens rapport, Värnkraft (2019) anser borde prioriteras fram till 2025.  I denna komparativa prediktionsstudie har tre olika alternativ av autonomi jämförts med hjälp av Analytic hierarchy process (AHP), för att analysera vilken grad av autonomi som har störst militär nytta för stridsfordonstransporter. Utgångspunkt för studien har varit utifrån ett scenario där förbandstransport av en mekaniserad bataljon genomförts. Som ingångsvärden för studien har litteraturstudier och intervjuer utifrån tekniken, autonominoch militära kontexten nyttjats. Resultatet indikerar att autonomi har militär nytta vid operativa stridsfordonstransporter genom att den taktiska tillgängligheten, operativa rörligheten och transportkapaciteten ökas. Möjlighet till autonomi minskar transporttiden vilket medger längre tid till förberedelser i insatsområdet för förbandet som transporterades. / Self-driving vehicles are no longer a utopian idea or something that you see in the movies. Today there are already fully functioning prototypes and several manufacturers claim they will have fully self-driving vehicles in just a few years’ time. In the civilian world, this new technology is expected to be capable of generating several resource efficiencies in road transportation. Increased capacity in unit combat vehicle transport capability and an increase in endurance, transportability and availability are factors that the Armed Forces' Perspective Study, as well as the Swedish Ministry of Defence´s study report Värnkraft, considers should be prioritized by 2025. In this comparative study, three different autonomy options have been compared, using the Analytic Hierarchy Process (AHP), to analyse what degree of autonomy has the greatest military utility for combat vehicle transport. The starting point of the study was based on a scenario where the transportation of a mechanized battalion had been carried out. The sources of information ​​for the study were literature studies and interviews based on technology, autonomy and the military context. The results indicate some degree of autonomy has military utility in the long-distance transportation of combat vehicles, by increasing tactical availability, operational mobility and transport capacity. Autonomy reduces transport time, allowing longer preparation time for the transported unit in the combat zone.
87

Untersuchungen zur Prädiktivität des versuchstierfreien Micronucleustests am angebrüteten Hühnerei (Hen´s Egg Test for Micronucleus-Induction, HET-MN)

Greywe, Daniela 09 May 2011 (has links)
Der Hen´s Egg Test for Micronucleus-Induction (HET-MN) wurde bereits mehrfach als ein alternatives, versuchstierfreies Testsystem für in-vivo Mutagenitätstests am Nager unter Verwendung von angebrüteten Hühnereiern vorgestellt (Wolf and Luepke 1997; Wolf, Niehaus-Rolf et al. 2002; Wolf, Niehaus-Rolf et al. 2003; Wolf, Niehaus-Rolf et al. 2008). Während der häufig verwendete in-vivo Micronucleustest am Nager aufgrund seines komplexen in-vivo Stoffwechsel für die Bewertung von Mutagenen sehr gute Ergebnisse liefert (Wolf 2003), können Alternativen zur Testung am Tier, zum Beispiel in-vitro Micronucleustests, die Vorteile der in-vivo Testung nicht erreichen, weshalb sie häufig zu sensitiv sind. Gegenüber herkömmlichen in-vitro Tests stellt die Komplexität des angebrüteten Hühnereis, welches sowohl toxikodynamische als auch toxikokinetische Wirkungen der Prüfsubstanz aufzeigen kann, einen besonderen Vorteil dar, so dass der HET-MN unter anderem nicht nur direkte Mutagene sondern auch Promutagene detektieren kann. Mit Hilfe von zehn ausgewählten Substanzen wurde in dieser Arbeit die Prädiktivität des HET-MN weiter untersucht. Hierzu gehörten, neben den in-vitro und in-vivo negativen Stoffen Ephedrin-HCl und Ampicillin-Natrium und den in-vitro und in-vivo positiven Substanzen para-Chloranilin, Carbendazim und Vinorelbintartrat, auch die fünf so genannten irrelevant positiven Substanzen Isophoron, 2,4-Dichlorphenol, Phthalsäureanhydrid, Menthol und Malathion, für die uneinheitliche in-vivo und in-vitro Daten vorliegen, die aber aufgrund validierter Testverfahren als in-vivo negativ eingestuft werden. Die im HET-MN ermittelten Ergebnisse zeigen für alle zehn Substanzen, im Vergleich zu den gängigen Einstufungen auf Grundlage validierter Tests, eine vollständige Übereinstimmung und damit eine sehr hohe Prädiktivität des HET-MN. Die Ergebnisse stärken daher die Position des HET-MN als einen zuverlässigen in-vitro Test mit besonderen metabolischen Fähigkeiten, der darüber hinaus dazu beitragen kann, so genannte irrelevant positive Substanzen besser einzustufen.
88

Social elements in English prose fiction between 1700 and 1832

Proper, Coenraad Bart Anne. January 1929 (has links)
Proefschrift--Amsterdam. / Bibliography: p. 291-302.
89

Het vertalen van spreektaal : Een vergelijking tussen de Zweedse vertalingen van spreektaal in twee kinderboeken van Guus Kuijer: Krassen in het tafelblad en Ik ben Polleke hoor! / Translating spoken language : A comparison of the Swedish translation of spoken language in two children's books by Guus Kuijer: Krassen in het tafelblad en Ik ben Polleke hoor!

Renting, Miriam January 2018 (has links)
In deze scriptie wordt onderzocht hoe spreektaal in de Nederlandse kinderboeken Krassen in het tafelblad en Ik ben Polleke hoor! vertaald is naar het Zweeds. De analyse is gemaakt volgens de theorie over vertaalnormen van de descriptieve vertaalwetenschap, en uitdrukkingen van spreektaal worden geanalyseerd vanuit Lindqvists (2005) indeling op drie niveaus: fonologisch/ morfologisch niveau, lexicaal niveau en syntactisch niveau. Het onderzoek toont aan welke strategie de vertalers mee hebben gewerkt en de vertaalnormen die mogelijk invloed hebben gehad tijdens het vertalen. Het resultaat wijst op dat de spreektaal in Krassen in het tafelblad vrijer vertaald is dan de spreektaal in Ik ben Polleke hoor!. Beide vertalingen tonen een streven aan om binnen de doelcultuur te passen, maar Krassen in het tafelblad ligt dichter bij een aanvaardbare vertaling dan Ik ben Polleke hoor!, die zich dichter bij de brontekst bevindt en gezien kan worden als een meer adequate vertaling. / This thesis examines how spoken language in the Dutch children's books Krassen in het tafelblad and Ik ben Polleke hoor! has been translated into Swedish. The analysis is done according to the descriptive translation studies’ theory of translation norms, and spoken language expressions are analyzed by using Lindqvist's (2005) classification of spoken language markers on three levels: the phonological/ morphological level, the lexical level and the syntactic level. The survey shows the translation strategies used by the translators and the norms that may have had an impact during the translation process. The result shows that the spoken language in Krassen in het tafelblad is more freely translated than the spoken language in the translation of Ik ben Polleke hoor!. Both translations show an ambition to fit within their target culture, but Krassen in het tafelblad lies closer to an acceptance-oriented translation than Ik ben Polleke hoor!, that adheres more to the source text and can be seen as a more adequate-oriented translation.
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Die Agterhuis – Lina Spies se vertaling van Anne Frank se dagboek, Het Achterhuis, in Afrikaans : besluite, benaderings en strategieë

Spies, Carla-Marie 03 1900 (has links)
Thesis (MPhil (Afrikaans and Dutch))--University of Stellenbosch, 2010. / ENGLISH ABSTRACT: This study investigates the translation approaches and strategies used by Lina Spies in her translation of Anne Frank's diary, Het Achterhuis, from Dutch into Afrikaans (Die Agterhuis). The researcher mainly works descriptively to discuss the decisions made regarding translation approaches and strategies adopted and applied in this translation. However, when necessary, a critique of the translation is also offered. The first chapter deals with the background of, and rationale for, the study; it provides a hypothesis, problem statement, methodology and the research questions. The next chapter provides background information on the source text, as well as considering reasons why this source text was translated into Afrikaans. The translator (Spies) as an agent of power is discussed as well. In the third chapter, the literature review, the most prominent translation theories which are relevant to this study are discussed. There are amongst others focused on functionalism (Nord 1997), intercultural communication (Katan 200), descriptive translation studies (DTS) (Toury 1995), and foreignization and domestication (Venuti 1995). Chapters 4 and 5 present the practical application/empirical study. In the macro-analysis aspects such as genre, overall translation approach and the paratext are looked at. The micro-analysis investigates the translation strategies which were used on the micro-level in order to achieve the overall effect this translation has on macro-level. Pragmatic, intercultural, interlinguistic and text-specific translation problems/challenges and the way that Spies (possibly) resolved these in the target text are discussed. The conclusion is drawn that Spies adopts a functionalist approach towards the translation as she takes into consideration both Nord's (1995) yardsticks for a "good"/"adequate" translation, namely (1) the source text and source text author, as well as (2) the target text reader. The foreignization approach is the primary approach used in this translation and the translator is very faithful to the source text and loyal to the source text author. Domestication is used as a secondary approach as the target text is made accessible to the target text reader on a grammatical level. The thesis finds that the authenticity of the source text and the literary value of this text are preserved, and that the voice and style of the source text author are conveyed to the target text reader. / AFRIKAANSE OPSOMMING: In hierdie studie word ondersoek ingestel na die vertaalbenaderings en -strategieë wat Lina Spies gebruik in die vertaling van Anne Frank se dagboek, Het Achterhuis uit Nederlands in Afrikaans (Die Agterhuis). Die navorser gaan hoofsaaklik deskriptief te werk om die besluitneming ten opsigte van watter vertaalbenaderings en vertaalstrategieë wat gevolg en toegepas word, te beskryf. Kritiek word wel uitgespreek waar nodig. Die eerste hoofstuk behels die agtergrond en rasionaal vir die studie, 'n hipotese, probleemstelling en navorsingsvrae en beskryf die metodologie wat in die tesis gevolg word. Die volgende hoofstuk verskaf 'n agtergrond van die bronteks en redes vir die vertaling daarvan in Afrikaans. Daar word hier ook na die vertaler (Spies) as magsagent gekyk. In die daaropvolgende hoofstuk, die literatuurstudie, word die vernaamste vertaalteoretiese benaderings bespreek wat van toepassing is op hierdie studie. Belangrike teorieë waarop daar gefokus word, is funksionalisme (Nord 1997), interkulturele kommunikasie (Katan 2004), deskriptiewe vertaalstudies (Toury 1995) en vervreemding en domestikering (Venuti 1995). Hoofstuk 4 en 5 beslaan die praktiese toepassing/empiriese studie. In die makro-analise word aspekte soos die genre, oorkoepelende vertaalbenadering en parateks bespreek. In die mikroanalise word daar gekyk na die vertaalstrategieë wat op mikrovlak gevolg is om die effek wat die doelteks op makrovlak het, te bewerkstellig. Daar word gekyk na pragmatiese, interkulturele, intertalige en teksspesifieke vertaalprobleme/-uitdagings en Spies se oplossings (of pogings tot oplossings) daarvoor. Daar word na afloop van die studie tot die gevolgtrekking gekom dat Spies funksionalisties te werk gaan, aangesien sy albei Nord (1995) se maatstawwe vir 'n "goeie"/"voldoende" vertaling, naamlik, eerstens, die bronteks en bronteksouteur, sowel as, tweedens, die doelteksleser, in ag neem. Die vervreemdingsbenadering word hoofsaaklik in die vertaling gevolg en daar word baie lojaal aan die bronteksouteur en getrou aan die bronteks gebly. Domestikering word as sekondêre benadering gevolg, deurdat die doelteks meestal grammatikaal toeganklik vir die doelteksleser gemaak word. Daar word bevind dat die outentiekheid van die bronteks en die literêre waarde daarvan, sowel as om die stem en styl van die bronteksouteur in die doelteks behou word.

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