The Service-Oriented Architecture (SOA) has become one of the most popular approaches to building large-scale network applications. The web service technologies are de facto the default implementation for SOA. Simple Object Access Protocol (SOAP) is the key and fundamental technology of web services. Service composition is a way to deliver complex services based on existing partner services. Service orchestration with the support of Web Services Business Process Execution Language (WSBPEL) is the dominant approach of web service composition. WSBPEL-based service orchestration inherited the issue of interoperability from SOAP, and it was furthermore challenged for performance, scalability, reliability and modifiability. I present an architectural approach for service composition in this thesis to address these challenges. An architectural solution is so generic that it can be applied to a large spectrum of problems. I name the architectural style RESTful Service Composition (RSC), because many of its elements and constraints are derived from Representational State Transfer (REST). REST is an architectural style developed to describe the architectural style of the Web. The Web has demonstrated outstanding interoperability, performance, scalability, reliability and modifiability. RSC is designed for service composition on the Internet. The RSC style is composed on specific element types, including RESTful service composition client, RESTful partner proxy, composite resource, resource client, functional computation and relaying service. A service composition is partitioned into stages; each stage is represented as a computation that has a uniform identifier and a set of uniform access methods; and the transitions between stages are driven by computational batons. RSC is supplemented by a programming model that emphasizes on-demand function, map-reduce and continuation passing. An RSC-style composition does not depend on either a central conductor service or a common choreography specification, which makes it different from service orchestration or service choreography. Four scenarios are used to evaluate the performance, scalability, reliability and modifiability improvement of the RSC approach compared to orchestration. An RSC-style solution and an orchestration solution are compared side by side in every scenario. The first scenario evaluates the performance improvement of the X-Ray Diffraction (XRD) application in ScienceStudio; the second scenario evaluates the scalability improvement of the Process Variable (PV) snapshot application; the third scenario evaluates the reliability improvement of a notification application by simulation; and the fourth scenario evaluates the modifiability improvement of the XRD application in order to fulfil emerging requirements. The results show that the RSC approach outperforms the orchestration approach in every aspect.

Despite years of research, the role that hypovolemia plays in orthostatic intolerance after head down bed rest (BR) and spaceflight remains unclear. Additionally, the efficacy of oral saline countermeasures, employed in an attempt to restore plasma volume (PV) after BR is questionable. Several previous studies have suggested that a new homeostatic set point is achieved in space or during BR, making attempts to restore PV temporary at best. We tested the hypotheses that one day of BR would induce a transient increase in PV followed by hypovolemia and new hormonal balance; that a salt tablet and water fluid loading (FL) countermeasure would be ineffective in restoring PV; and also that the FL would not attenuate the exaggerated hormonal responses to orthostatic stress that are expected after 28hr of BR. Plasma volume, serum sodium and osmolarity, and plasma ANP, AVP, renin, angiotensin II, aldosterone, and catecholamines were measured in nine male subjects undergoing 5 different protocols (28hr Bed Rest without Fluid Loading = 28NFL, 28hr Bed Rest with Fluid Loading = 28FL, 4hr Seated Control = 4NFLS, 4hr Seated Control with Fluid Loading = 4FLS, and 4hr Bed Rest = 4BR) in a randomized repeated measures design. The FL countermeasure was 15 ml/kg of body weight of water with 1g of NaCl per 125ml of water. Orthostatic testing by lower body negative pressure (LBNP) was performed before and after all protocols. In agreement with our first hypothesis, we observed transient reductions in renin, angiotensin II, and aldosterone, which after 25.5hr were restored to baseline, slightly augmented, and suppressed, respectively. Also after 25.5hr, PV was reduced in the 28hr BR protocols and was not restored in 28FL; however, the FL protocol increased PV during 4FLS. We additionally observed augmented renin and aldosterone responses, as well as generally elevated angiotensin II after 28NFL, but not after 28FL or any of the 4hr protocols. Furthermore, no changes in plasma norepinephrine responses to LBNP were documented from Pre-Post test in any protocol. Our results indicate that: 1) PV is reduced after short term BR and is not restored by an oral FL; 2) renin-angiotensin-aldosterone system (RAAS) responses to orthostatic stress are augmented after 28hr of BR and the amplified response can be abrogated by FL; and 3) plasma norepinephrine responses during orthostatic stress are not affected by BR or FL, suggesting that RAAS activity may be modulated by FL independently of sympathetic activity and PV during orthostasis after bed rest.

Remote Explosives Scent Tracing (REST) is the concept of bringing the mine field to Mine Detection Dogs or Rats, instead of vice versa. This is done by collecting air or dust from minefields, and taking these samples to a laboratory environment, where they are subsequently analysed by the detection animals. REST has previously proven to be very fast and cost effective, but one of the issues facing the method is that there is yet no reliable tool for sampling dust. In earlier sampling units, air has been collected in filters. However, the concentration of scents related to mines has been seen to be a million times higher in dust particles than in air sampled from above the ground. The aim of this project was to evaluate and improve a dust sampling prototype constructed in the beginning of 2010. The project was initiated in cooperation with the GICHD (Geneva International Centre for Humanitarian demining), and carried out in cooperation with APOPO (Anti-Personnel Landmines Detection Product Development). During this project, information was gathered on the samplers that have previously been used for REST. A new prototype was made in Trondheim in cooperation with NTNU (Norwegian University of Science and Technology). With this new sampler prototype, tests were made in a laboratory environment at NTNU as well as at APOPO’s test mine field in Morogoro, Tanzania. Several obstacles were faced, such as difficulties to test and evaluate the sampler during the rainy season, insufficient air supply for the prototype, and issues with the laboratory equipment in Morogoro. Due to this, the number of tests performed and the number of repetitions of each test was not as high as would have been desired. The results of the information gathering and the tests are presented in this report, and the knowledge and experience gained resulted in several suggestions for improvements for the sampler prototype. A suggestion for a grid design that would cover the entire mouth piece, with a built-in distance to the suction inlet, in order to avoid both clogging of the grid and that too much dust is sucked in if the mouth piece touches the ground and a fully adjustable sampling unit. Several other recommendations are given that would reduce cross contamination risks and improve ergonomics and other aspects of the sampler prototype.

This study was designed to test the hypothesis that 60 days continuous head down bed rest (HDBR), an Earth-based analogue of the effects of space flight, would elevate factors that increase vasoconstriction and would increase markers of vascular inflammation. The study incorporated countermeasures consisting of treadmill running within lower-body negative pressure and resistive "flywheel" exercise (exercise countermeasure, EX) or an increased protein intake of 0. 6 g/kg body weight/day (dietary countermeasures, DIET) to determine whether these interventions might prevent the vasoconstrictor and inflammatory responses when compared to a control (CON) group. Markers of vascular health measured in the study include the vasoactive molecules angiotensin II (Ang II), endothelin-1 (ET-1), and nitric oxide metabolites (NO_met); and markers of inflammation including C-reactive protein (CRP), and the adhesion molecules E-selectin (E-sel), intracellular adhesion molecule-1 (ICAM), and vascular cell adhesion molecule-1 (VCAM). Twenty four women were housed at the MEDES clinic in Toulouse, France, as part of a large international study (Women International Space Simulation for Exploration, WISE) in which various experimental protocols and countermeasures were integrated into a single experimental design completed during two campaigns. Each 100 day campaign included 20 days of pre-testing (pre-HDBR), 60 days of bed rest (HDBR), and 20 days of post-testing (post-HDBR). The experimental countermeasures were applied only during the 60-day HDBR period. Following 60 days of HDBR, many changes occurred in the concentrations of the measured molecules. Specifically, the concentration of Ang II significantly increased in the CON and DIET groups (52. 9%, p = 0. 014; and 124. 4%, p <0. 0001 respectively), but not in the EX group. Also, NO_met decreased in all groups, with reductions in the EX and DIET groups (p = 0. 013, and p = 0. 056 respectively). Markers used to assess vascular inflammation increased following the HDBR. The increase in CRP in the CON and DIET groups and the decrease in the EX group from pre- to post-HDBR were not significant; however, the directional changes resulted in an interaction between group and HDBR (p = 0. 052). The adhesion molecule E-sel was significantly increased in the DIET group (p = 0. 003), and VCAM was significantly increased in the CON group (p = 0. 016) with a smaller increase in the DIET group (p = 0. 08). No changes in adhesion molecules were observed in the EX group. This study demonstrated that 60 days of HDBR by young, healthy, women caused changes in several different molecules that are beginning to emerge as risk factors for the development of cardiovascular diseases. Further, it was observed that regular, vigorous exercise during HDBR prevented these changes. These results suggest that future studies of this kind should directly monitor the effects of simulated space flight on vascular health in men and women to obtain a greater understanding of the adaptations that might occur during long term space exploration missions. HDBR can be considered an extreme model of physical inactivity and could be used to provide insight into mechanisms of disease processes associated with the sedentary lifestyle that is prevalent in Western society.

Despite years of research, the role that hypovolemia plays in orthostatic intolerance after head down bed rest (BR) and spaceflight remains unclear. Additionally, the efficacy of oral saline countermeasures, employed in an attempt to restore plasma volume (PV) after BR is questionable. Several previous studies have suggested that a new homeostatic set point is achieved in space or during BR, making attempts to restore PV temporary at best. We tested the hypotheses that one day of BR would induce a transient increase in PV followed by hypovolemia and new hormonal balance; that a salt tablet and water fluid loading (FL) countermeasure would be ineffective in restoring PV; and also that the FL would not attenuate the exaggerated hormonal responses to orthostatic stress that are expected after 28hr of BR. Plasma volume, serum sodium and osmolarity, and plasma ANP, AVP, renin, angiotensin II, aldosterone, and catecholamines were measured in nine male subjects undergoing 5 different protocols (28hr Bed Rest without Fluid Loading = 28NFL, 28hr Bed Rest with Fluid Loading = 28FL, 4hr Seated Control = 4NFLS, 4hr Seated Control with Fluid Loading = 4FLS, and 4hr Bed Rest = 4BR) in a randomized repeated measures design. The FL countermeasure was 15 ml/kg of body weight of water with 1g of NaCl per 125ml of water. Orthostatic testing by lower body negative pressure (LBNP) was performed before and after all protocols. In agreement with our first hypothesis, we observed transient reductions in renin, angiotensin II, and aldosterone, which after 25.5hr were restored to baseline, slightly augmented, and suppressed, respectively. Also after 25.5hr, PV was reduced in the 28hr BR protocols and was not restored in 28FL; however, the FL protocol increased PV during 4FLS. We additionally observed augmented renin and aldosterone responses, as well as generally elevated angiotensin II after 28NFL, but not after 28FL or any of the 4hr protocols. Furthermore, no changes in plasma norepinephrine responses to LBNP were documented from Pre-Post test in any protocol. Our results indicate that: 1) PV is reduced after short term BR and is not restored by an oral FL; 2) renin-angiotensin-aldosterone system (RAAS) responses to orthostatic stress are augmented after 28hr of BR and the amplified response can be abrogated by FL; and 3) plasma norepinephrine responses during orthostatic stress are not affected by BR or FL, suggesting that RAAS activity may be modulated by FL independently of sympathetic activity and PV during orthostasis after bed rest.

This thesis sets out to analyze how restricting rest (sleep) locations for long-haul truckers may impact operational productivity, given hours-of-service regulations. Productivity in this thesis is measured by the minimum number of unique drivers required to feasibly execute a set of load requests over a known planning horizon. When drivers may stop for rest at any location, they may maximize utilization under regulated driving hours. When drivers may only rest at certain discrete locations, their productivity may be diminished since they may no longer be able to fully utilize available service hours. These productivity losses may require trucking firms to operate larger driver fleets. This thesis addresses two specific challenges presented by this scenario; first, understanding how a given discrete set of rest locations may affect driver fleet size requirements; and second, how to determine optimal discrete locations for a fixed number of rest facilities and the potential negative impact on fleet size of non-optimally located facilities. The minimum fleet size problem for a single origin-destination leg with fixed possible rest locations is formulated as a minimum cost network flow with additional bundling constraints. A mixed integer program is developed for solving the single-leg rest facility location problem. Tractable adaptations of the basic models to handle problems with multiple lanes are also presented. This thesis demonstrates that for typical long-haul lane lengths the effects of restricting rest to a relatively few fixed rest locations has minimal impact on fleet size. For an 18-hour lane with two rest facilities, no increase in fleet size was observed for any test load set instances with exponentially distributed interdeparture times. For test sets with uniformly distributed interdeparture times, additional required fleet sizes ranged from 0 to 11 percent. The developed framework and results should be useful in the analysis of truck transportation of security-sensitive commodities, such as food products and hazardous materials, where there may exist strong external pressure to ensure that drivers rest only in secure locations to reduce risks of tampering.

Due to the consideration of economic dispatch or system operation, the regional severe unbalance between power generation and load demand will introduce large amount of power flow over the inter-area tie lines. The tripping of transmission lines due to power system fault contingency will result in the increase of power flow over the inter-area tie lines, which may violate the constraint of transient stability. The whole power system could be collapsed due to further tripping of more generators unless proper remedy actions are executed in tie. This thesis proposes an effective approach to determine the generators to be tripped for power system protection. All of the generators in the power system are divided into critical group and non-critical group based on the methods of Energy-gap and Impedance-gap. The power flow capability limit of transmission lines on inter-areas have been derived by transient stability analysis. Once fault contingency occurs on the power system, the power flow of transmission lines on inter-area is compared to the above transmission limit to determine the generators in the critical group to be tripped. By this way, the stable operation of power system can be maintained after the contingency. To demonstrate the effectiveness of the proposed methodology, the Taipower system is selected for computer simulation to verify the generator tripping by system transient stability analysis. Different scenarios of system fault contingencies on primary EHV substations with various power flow conditions over the inter-area tie lines have been investigated to confirm the power system performance by applying the proposed generator tripping.

<p>Remote Explosives Scent Tracing (REST) is the concept of bringing the mine field to Mine Detection Dogs or Rats, instead of vice versa. This is done by collecting air or dust from minefields, and taking these samples to a laboratory environment, where they are subsequently analysed by the detection animals.</p><p>REST has previously proven to be very fast and cost effective, but one of the issues facing the method is that there is yet no reliable tool for sampling dust. In earlier sampling units, air has been collected in filters. However, the concentration of scents related to mines has been seen to be a million times higher in dust particles than in air sampled from above the ground. The aim of this project was to evaluate and improve a dust sampling prototype constructed in the beginning of 2010. The project was initiated in cooperation with the GICHD (Geneva International Centre for Humanitarian demining), and carried out in cooperation with APOPO (Anti-Personnel Landmines Detection Product Development).</p><p>During this project, information was gathered on the samplers that have previously been used for REST. A new prototype was made in Trondheim in cooperation with NTNU (Norwegian University of Science and Technology). With this new sampler prototype, tests were made in a laboratory environment at NTNU as well as at APOPO’s test mine field in Morogoro, Tanzania. Several obstacles were faced, such as difficulties to test and evaluate the sampler during the rainy season, insufficient air supply for the prototype, and issues with the laboratory equipment in Morogoro. Due to this, the number of tests performed and the number of repetitions of each test was not as high as would have been desired.</p><p>The results of the information gathering and the tests are presented in this report, and the knowledge and experience gained resulted in several suggestions for improvements for the sampler prototype. A suggestion for a grid design that would cover the entire mouth piece, with a built-in distance to the suction inlet, in order to avoid both clogging of the grid and that too much dust is sucked in if the mouth piece touches the ground and a fully adjustable sampling unit. Several other recommendations are given that would reduce cross contamination risks and improve ergonomics and other aspects of the sampler prototype.</p>

A major hurdle for any company to cross is the act of re-engineering software if they wish to stay relevant. With the speed that software and technology advances, it would be ignorant for any product to stagnate. With that comes the inherent difficulties of choosing which of the older technologies to keep (if any) and which newer technologies to employ in the re-engineered solution. Once that is covered, the actual implementation presents its own set of challenges to both the decision makers and developers in the process. This thesis describes a case study, in particular the efforts put forth to re-engineer some specific software. While the software is quite capable, it is becoming more and more out-dated every passing year, not to mention more difficult to maintain, upgrade and alter, providing a perfect example to explore. The focus of this thesis is to discuss what avenues of upgrading and methods of providing comparable or improved services to the end user our team chose and implemented. These include using a relational database with an advanced object-relational mapper in a modern environment to provide a REpresentational State Transfer (REST) web service that will then supply a rich interactive front-end. Taken together, these tools are quite powerful and capable.

Aim of the study: to analyze and compare work and leisure regime of urban and rural middle-school-age students. Objectives: 1. To evaluate passive and active leisure of schoolchildren in relation with health. 2. To evaluate learning process of schoolchildren. 3. To evaluate nourishment regime of schoolchildren in relation with health. Methods: The research was conducted in October – November 2004. Anonymous questionnaire was used for the survey. The final version of the questionnaire includes 40 questions. Schoolchildren from grade 6th to grade 8th from Birzai and Kaunas took part in the survey. 310 students were questioned in total. Received survey data were converged for the statistic computer analysis. The statistic data analysis was carried out by using statistic package “SPSS 11.5”. Results: Schoolchildren from both cities usually have a feeling of not getting enough sleep in the morning (33.8% of Birzai and 52.7% of Kaunas schoolchildren). Schoolchildren from Birzai spend more time watching TV during the week than schoolchildren from Kaunas (2 hours – students from Birzai, 1 hour 45 min – those from Kaunas). Pupils are not attending sports activities (70.4% Birzai, 49.3% Kaunas) however Kaunas pupils are more active than those from Birzai (p<0.001). 15.5% of Birzai and 6.6% of Kaunas schoolchildren have never had dinner on working days. 1.9% of Birzai pupils and 4.7% of Kaunas pupils never eat supper. Conclusions: Schoolchildren from Birzai spend more time watching... [to full text]