This work is a proposal for an alternative approach to working with print, making the printing process a key element within designing. It is an investigation into flat garment construction between fabric layers, as this enables for the printing to be used in place of sewing. Additionally, working with multiple textile layers connects with the reference of the peeling wallpaper, which is used as a base for material and form developments. The aim of the work is to develop a more holistic approach and new expressions in garment-making in relation to the application of printing processes within textile layers. The main objective is to present a new perspective of the relationship between garment pattern and print, bringing the later forward. Not only does the surface print, through the interaction of colour and texture provide an important element in terms of creating expression, but it additionally acts as a construction element. Moreover, by using the process of printing to create form the element of print becomes integrated into the process of garment-making.

Yes / 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP) is an enzyme that adds a single ADP-ribose moiety to itself or other proteins. Tiparp is highly expressed in the brain; however, its function in this organ is unknown. Here, we used Tiparp–/– mice to determine Tiparp’s role in the development of the prefrontal cortex. Loss of Tiparp resulted in an aberrant organization of the mouse cortex, where the upper layers presented increased cell density in the knock-out mice compared with wild type. Tiparp loss predominantly affected the correct distribution and number of GABAergic neurons. Furthermore, neural progenitor cell proliferation was significantly reduced. Neural stem cells (NSCs) derived from Tiparp–/– mice showed a slower rate of migration. Cytoskeletal components, such as α-tubulin are key regulators of neuronal differentiation and cortical development. α-tubulin mono-ADP ribosylation (MAR) levels were reduced in Tiparp–/– cells, suggesting that Tiparp plays a role in the MAR of α-tubulin. Despite the mild phenotype presented by Tiparp–/– mice, our findings reveal an important function for Tiparp and MAR in the correct development of the cortex. Unravelling Tiparp’s role in the cortex, could pave the way to a better understanding of a wide spectrum of neurological diseases which are known to have increased expression of TIPARP. / European Union Seventh Framework Program (FP7-PEOPLE-2013-COFUND) Grant n609020-Scientia Fellows (to G.G.) and by the Johan Throne Holst Foundation and the University of Oslo (J.M.).

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what follows is a relatively concise attempt at designing a place that would contain spaces of quietude, solitude and interaction through architectural qualities such as light and shadow, mass and void along with materials and layering. enjoyable and relaxing spaces that would last in one's memory. Hoping that these qualities would engrave a beautiful mark on one's soul even when they are no longer at that place. a complex of thermal baths in the city of isfahan, iran, a city rich in culture, made this exploration of mine pursuable and possible. / Master of Architecture

Under åren har intensiv forskning pågått för att förbättra maskininlärningsmodellers förmåga att förutse marknadsrörelser. Trots detta har det, under finanshistorien, inträffat flera händelser, såsom "Flash-crash", som har påverkat marknaden och haft dramatiska konsekvenser för prisrörelserna. Därför är det viktigt att undersöka hur modellerna påverkas av manipulativa handlingar på finansmarknaden för att säkerställa deras robusthet och tillförlitlighet i sådana situationer.  För att genomföra detta arbete har processen delats upp i tre steg. Först har en undersökning av tidigare arbeten gjorts för att identifiera de mest robusta modellerna inom området. Detta gjordes genom att träna modellerna på FI-2010 datasetet, som är ett offentligt tillgängligt dataset för högfrekvent handel med aktier på NASDAQ Nordic-börsen. De modeller som undersöktes inkluderade DeepLOB, DeepLOB-Attention, DeepLOB-seq2seq, DTNN och TCN. Det andra steget innefattade att köpa det svenska datasetet från Nasdaq Nordic, vilket tillhandahåller data om svenska aktier Limit Order Book (LOB). De två modellerna som visade bäst resultat i det första steget tränades sedan med detta dataset. Slutligen genomfördes en manipulation på de svenska orderböckerna för att undersöka hur dessa modeller påverkas. Resultatet utgjorde en tydlig bedömning av modellernas robusthet och pålitlighet när det gäller att förutse marknadsrörelser genom en omfattande jämförelse och analys av samtliga tester och deras resultat. Arbetet belyser även hur modellernas resultat påverkas av manipulativa handlingar. Dessutom framgår det hur valet av normaliseringsmetod påverkar modellernas resultat. / Over the years, intensive research has been conducted to enhance the capability of machine learning models to predict market movements. Despite this, during financial history, several events, such as the "Flash-crash," have impacted the market and had dramatic consequences for price movements. Therefore, it is crucial to examine how the models are affected by manipulative actions in the financial market to ensure their robustness and reliability in such situations. To carry out this work, the process has been divided into three steps. Firstly, a review of previous studies was conducted to identify the most robust models in the field. This was achieved by training the models on the FI-2010 dataset, which is a publicly available dataset for high-frequency trading of stocks on the NASDAQ Nordic stock exchange. The examined models included DeepLOB, DeepLOB-Attention, DeepLOB-seq2seq, DTNN, and TCN. The second step involved acquiring the Swedish dataset from Nasdaq Nordic, providing data on Swedish stock Limit Order Books (LOB). The two models that demonstrated the best results in the first step were then trained with this dataset. Finally, a manipulation was performed on the Swedish order books to investigate how these models would be affected. The result constituted a clear assessment of the models' robustness and reliability in predicting market movements through a comprehensive comparison and analysis of all tests and their results. The work also highlights how the models' outcomes are affected by manipulative actions. Furthermore, it becomes evident how the choice of normalization method affects the models' results.

This thesis tells the tales of auxiliation in Swedish. It describes how the auxiliary features of the aspectual auxiliaries bruka ‘use to’, tendera ‘tend to’, börja ‘begin, start’, fortsätta ‘continue’, sluta ‘stop, cease’ och hota ‘threaten’ evolve, as seen in a text corpora covering the 11th to the 21st century. A grammaticalization perspective is employed, which not unexpectedly has implications for the way data is interpreted and presented, but also less expectedly for how the method is understood and applied. The method consists of Swedish auxiliary tests, designed to reveal auxiliary features. The discussion of their validity involves auxiliation theory as well as a more general theoretical discussion of how the category and the function of auxiliaries have been conceived. The main point made is that a valid test should have an explicit link to auxiliary function. Establishing the nature of such a link, however, is no trivial matter and so the plausibility of the link turns out to be the main factor in judging the validity of auxiliary tests. In the early stages of the auxiliation processes, action nominals were often used as complements of the verbs under study. Later on these verbs started taking infinitive complements, lost their semantic restrictions on their subjects and started occurring in a type of passive construction where the nonfinite verb carries the semantic relationship to the arguments of the clause. The occurrence in this type of passive construction is perceived as the most plausible indication of auxiliary function available for subject raising auxiliaries, since the auxiliary and the nonfinite verb in these clauses do function together as one single predicate. The evolution of these aspectual auxiliaries essentially follows the predictions made by auxiliation theory. That said, they all show individual deviations from those predictions, depending on such factors as their semantics, their source construction and during which period in the history of Swedish their auxiliation took place.

Approved for public release; distribution in unlimited. / While a necessity of all operating systems, the code that initializes a system can be notoriously difficult to understand. This thesis explores the most common architectures used for bringing an operating system to its initial state, once the operating system gains control from the boot loader. Specifically, the ways in which the OpenBSD and Linux operating systems handle initialization are dissected. With this understanding, a set of threats relevant to the initialization sequence was developed. A thorough study was also made to determine the degree to which initialization code adheres to widely accepted software engineering principles. Based upon this threat analysis and the observed strengths and weaknesses of existing systems, a set of recommendations for initialization sequence architecture and implementation have been developed. These recommendations can serve as a guide for future operating system development. / Civilian, Naval Postgraduate School

Student Number : 0201438A - PhD thesis - School of Geosciences - Faculty of Science / This project focuses on the Upper Critical and Lower Main Zones in the eastern Bushveld Complex, South Africa. Lithological and stratigraphic information show that there are distinct differences at this level between the eastern and western limbs of the complex. Geochemical studies are centred on the Merensky and Bastard Cyclic Units in which the platiniferous Merensky Reef occurs. A major geochemical hiatus occurs in the Bushveld Complex at the level of the platiniferous Merensky Reef, close to the Critical/Main Zone boundary. The origin of this hiatus and its relation to mineralisation has not been fully resolved. Geochemical parameters are investigated that allow minerals in the Merensky and Bastard Cyclic Units to be classified as originating from either Critical or Main Zone magmas. Modelling of element ratios (Ni/Y, Cr/Ni, Cr/Co, Y/Co, Cr/V, Co/V and Cr/MgO) demonstrates the varying reliability of using ratios as geochemcial tools to constrain magma influxes within a chamber. However, it is shown that the Cr/MgO ratio is effective in determining real differences across the Critical/Main Zone boundary that are independent of lithology. In addition, initial Sr isotope ratios for plagioclase are significantly different in Critical and Main Zone rocks. Geochemical data through the Merensky and Bastard Cyclic Units indicate that orthopyroxene that originated from magma with composition like that of the Critical Zone magma sometimes occurs together with plagioclase that originated from Main Zone magma. In detail, in the pyroxenite at the base of the Merensky Unit, both plagioclase and orthopyroxene display Critical Zone signatures, but in the overlying part of the Merensky Cyclic Unit, plagioclase increasingly shows a Main Zone signature, whereas orthopyroxene continues to display a Critical Zone signature. Similarly, in the Bastard pyroxenite, Sr isotopes and absolute Sr in plagioclase display a range of values from Main Zone to Critical Zone, but orthopyroxene consistently displays Critical Zone affinity. These observations of mineral disequilibrium clearly show that the two major minerals in the Merensky and Bastard Cyclic Units were formed from two different, but coexisting, magmas. A model that accounts for this disequilibrium is proposed here. It invokes the influx of Main Zone magma at the level of the base of the Merensky unit that dispalced the Critical Zone magma upward, but the two magmas did not mix. The latter continued to crystallise orthopyroxene which sank through the Main Zone influx, due to its density contrast. These crystals collected on the crystal pile to form the Merensky pyroxenite. The Main Zone magma, into which the cumulus Critical Zone orthopyroxene accumulated, crystallised interstitial plagioclase that had a Main Zone Sr isotopic ratio. Whole-rock, major element geochemical data show that a variable proportion of the plagioclase in both the Merensky and Bastard pyroxenites is cumulus. It is inferred to have accumulated with orthopyroxene and has a Critical Zone initial Sr isotope ratio. Thus the two pyroxenites now yield a mixed Sr isotopic signature of Critical Zone cumulus and Main Zone intercumulus and possibly cumulus plagioclase that varies along strike. Above the two pyroxenites, the Sr signature of the norites and anorthosites of both cyclic units is dominated by cumulus plagioclase from the Main Zone magma. It is concluded that the variations in initial Sr isotope ratios do not result from mixing of magmas, but result from accumulation of orthopyroxene and plagioclase from a higher, isotopically distinct layer of magma into an underlying layer. The Merensky and Bastard Cyclic Units therefore display features of Critical or Main Zone magma characteristics depending upon which chemical parameter is considered. These cycles are therefore classified as a Transitional Unit.

This thesis suggests the concept of layering as a &ldquo / generative&rdquo / operation in architectural design process. To understand generation of architectural forms and trace their transformations in this process, this study proposes layering as an integrative and intellectual operation embracing analysis, design and representation phases of architecture. In order to do that, the operation of layering is discussed under three titles: Layering as an analytical tool, as a design tool and as a representational tool. This means that, &ldquo / layering&rdquo / can operate to understand complex forms (to analyze), to generate space (to design), and to communicate in design process (to represent). In this context, for a deeper inquiry into the operation of layering, House II designed by Peter Eisenman is analyzed. The complex and layered form of House II addresses an extensive formal analysis that attempts to reveal the formations and transformations of layers constituting the building. Considering the building as a formal system, &ldquo / layers&rdquo / are defined as the fragments of the whole, and &ldquo / layering&rdquo / is conceptualized as the main operation that organizes relationships between these fragments. These analyses reveal the multi-layered formation of House II. Creating an architectural system, the operation of layering has the capacity to organize varied architectural elements by defining relationships in-between them.