Flash is the unwanted or excessrubber material that presents on the outersurface of themolded rubber product. This will affect the surface finish; it is a cosmetic defect andit can be removed. It forms because of the leak or the excess molded rubber materialbetween the surface of the mold, typically on the parting line, (Jordan Anderson,2014). The presence of flash will reduce customer satisfaction. There are manymethods to remove the flash. The method is selected according to the degree of flashextension and the location where it occurs.The project aims to design a semi/full automated machine, which helps for having asmooth and fine surface finish of the weight plates. These plates are made up of rubberfor the ELEIKO group. The weight plates have different weights from 10 to 20 kg,but the diameter of each plate stays the same, but the thickness will be different foreach plate. The machine should be designed that removes all the excess rubber andshould smoothen the outer surface of the weight. The purpose of this work is to gainknowledge about different product development methods, respective tools, andtechniques that are used. The machine should be user- friendly, should not becomplicated, should not damage the workpiece (marks or trace of the blade), shouldnot put the employer in danger, and economically feasible.This report presents the progress of designing of the product, product development,methods, and literature study. The designed model can construct in the industry fortheir problem they are faced by the flash. The model is very simple and unique so thateveryone can perform the task without any previous experience. Material alternativeswere evaluated as well as manufacturing possibilities. The designed machine was theoffered for free as means for further research and development. Keywords: flashing, additive manufacturing, Ullman method, Pugh matrix, rubberweight plates, lever arm, smoothening tool.

New technology in the automotive industry is the key to success. Therefore, it is appreciated when people come with new design ways to solve problems. This leads to innovation in the automotive industry that will lead to better and more environmentally friendly cars. This report presents a concept on a pushing counter lever spring which provides the same characteristics of force curve as a diaphragm spring in a pressure plate of a car has. The mechanism is to be used for long-term testing and evaluating clutch pedals. The work describes the development process and the manufacture of a prototype. The program Creo (CAD / 3D) is largely used to construct the components. As are the subprograms Mechanism Design and Simulate to simulate the movement and loads. Excel is a great help at the theoretical calculation of the mechanism and to evaluate the theory behind the concept. The result shows how to simulate a diaphragm spring in the pressure plate in a car for long-term testing of clutch pedals. The goal is to accurately mimic the force curve of a diaphragm spring, in order to design better pedals, and thus reduce the weight on the pedals to in turn reduce fuel consumption to protect the environment is one of the most important factors of all in the automotive industry.

Dissertação apresentada para obtenção do grau de Mestre em Engenharia do Ambiente, apresentada na Faculdade de Engenharia da Universidade do Porto, sob a orientação dos Prof. Doutor Chia-Yau Cheng e Prof. Doutor Tentúgal Valente

The purpose of this dissertation was to determine if the New Lifestyles NL-2000 (NL) and the Digi-Walker SW-200 (DW), waist-mounted devices, yield similar daily step counts as compared to the StepWatch 3 (SW), an ankle-mounted device, worn by adults and children in the free-living environment. For the first study, fifty-six adults (32.7 + 14.5 y) wore the devices for seven consecutive days. There were 20 normal weight, 18 overweight, and 18 obese participants. The NL and DW undercounted (pedometer error) similarly in the normal weight and overweight groups (-15.4% to -18.2%, respectively). However, the DW undercounted more than the NL in the obese group (-32.8% vs -23.9%, respectively). Stepwise regression revealed that both the NL and DW had more error (undercounted more) as a greater percentage steps were accumulated while walking slowly. The DW also had more error with greater BMI. Use of the DW in an obese population will result in twice the error as compared to a normal weight population and thus the DW should not be used to determine relationships between walking volume and adiposity For the second study, 74 children (13 ± 1.1 y) wore the same devices during one weekday. There were 33 normal weight, 21 overweight, and 20 obese participants. The error was determined for the NL and DW, and the values were similar in the normal weight and overweight groups (-10.8% to -15.4%, respectively). The DW undercounted more than the NL in the obese group (-27.3% vs -8.4%, respectively). The NL was very consistent regardless of BMI category, recording 89.1% (-10.8% error), 89.1% (-10.9% error), and 91.6% (-8.4% error) for the normal weight, overweight, and obese participants, respectively. Stepwise regression revealed that the DW undercounted more in participants with a high weight. Using the DW in obese children of this age group will result in significantly more undercounting when compared to normal weight children. The DW should not be used to determine relationships between walking volume and adiposity in this population. The NL undercounted by ~10%, regardless of BMI category.

Although two-thirds of colorectal cancer patients are cured by surgery, approximately 50% of the patients with this disease develop locally recurrent or distant metastases during the course of their illness. The aim of this study was to identify metastatic sites associated with poor prognosis in rectal cancer and then to investigate methods that can prevent the development and growth of metastases and optimise uptake of drugs at these sites in animal models. In a defined population, 151 patients with irresectable metastatic or local rectal cancer were identified. Bilateral liver involvement, abnormal liver function tests, paritoneal growth or abdominal lymph node metastases implied a poor prognosis. In a study on Wistar rats with liver metastases from colorectal cancer, blocking of hyaluronan uptake and elimination by the liver enhanced the hyaluronan uptake in liver metastases. Hyaluronan may thus be used to promote uptake of drugs in specific hyaluronan receptor-positive turnout sites. Adjuvant intravenous radioimmunotherapy delivered as a specific or unspecific monoclonal antibody prevented human colonic cancer calls inoculated into the portal vein of nude rats from developing into liver metastases. Furthermore, intraperitoneally administered radioimmunotherapy inhibited the growth of peritoneal metastases. Blocking of 5-FU absorption with a vasoconstrictive agent enhanced the uptake of 5-FU in peritoneal metastases. In addition, the uptake of 5-FU in peritoneal metastases could be improved when these turnouts were mechanically disintegrated by surgical turnout reduction and the drug was given intraperitoneally.

An epicyclic gear mechanism for automobile transmissions is a device which is connected from engine to driving wheels, and the main purpose is to maintain the revolution speed of engine to be in a desired working range while accelerating or decelerating the automobile. The epicyclic gear mechanisms for automobile transmissions in production are mostly Ravigneaux-type, Parallel-connected type and Lepelletier epicyclic mechanisms, and the Lepelletier epicyclic gear mechanisms is a device which is connected with a simple epicyclic gear mechanism besides the input end to increase the total number of speed ratios of an automatic transmission. For the incompletion in the relative design methodology, a systematic methodology of designing Lepelletier epicyclic gear mechanisms for automobile transmission is described. At first, fundamental and gear-shifting operations of the Lepelletier-type automatic transmissions is introduced, and the basic principles of lever analogy is explained, the gear ratio¡¦s analysis for Lepelletier epicyclic gear mechanisms is illustrated to establish the design requirements. Secondly, gearing-sequence is devised base on the lever analogy diagrams, and a systematical procedure to arrange desired clutches and brakes into epicyclic gear mechanisms is provided, then the number of the teeth of all gears can be calculated. At last, the six-speed and eight-speed Lepelletier automatic transmissions are designed base on the above design procedure. The results of this work obtain 19 types of automatic transmission which could reach six-speed.

There are many advantages of Epicyclic gear type automobile transmissions. It is composed more densely and weights lighter. It provides higher gear ratio and can transmit power differentially. Therefore, this type of transmissions are applied to almost every automobiles in recent years. However, the design process of an Epicyclic gear type automobile transmission is more complicated than Counter shaft type one. In the world, there are just two kinds of 8-speed Epicyclic gear type automobile transmission in production. This study introduced a design methodology of Parallel epicyclic gear type automobile transmission by decomposing and recomposing of Lever diagram. First we drew the Lever diagram from given rotation speed ratios. Next we listed all 3-point lever diagrams which are decomposed from the original Lever diagram, and deleted those with unreasonable value of K. Then we listed all combinations of 3-point lever diagram which composed the original Lever diagram, and we got all feasible epicyclic gear train mechanisms. After choosing feasible epicyclic gear train mechanism, we set up necessary clutches and breakes in clutch graphs. Finally, based on the clutch graph, we draw the schematic diagram of mechanisms, and embodies out results. Methodology of this study is better than old ones because our methodology based on Lever diagram did not need to find the usable mechanisms from the catalog of epicyclic gear train mechanisms. Thus, the new methodology simplifies the process of designing a epicyclic gear type automobile transmission.

Epicyclic-type automatic transmissions are used in automobiles widely. There are many advantages of epicyclic-type automatic transmissions. It is composed more densely, smaller and provide higher gear ratio. We can get different output speed by actuating different clutches or brakes. There are a lot of patents for epicyclic-type automatic transmissions, but most of them tends to be three degrees of freedom automatic transmissions or using embedded clutches or brakes and other complex constructions. It is a better choice if we could use relatively simple manufacturing and control of two degrees of freedom and external clutches and brakes in the same multi speeds, speed ratio of the same premise. Therefore, this study aims to propose a set of design process for two degrees of freedom parallel-connected epicyclic gear automatic transmissions and computerize the process. First, we established the lever diagram for eight-speed automatic transmissions. By decomposing lever diagrams to all possible three-point lines, then composing four different lines to get all possible eight-speed automatic transmission constructions. Then, we use direct-member -number method to get member number of all constructions. Determining the possibility of configuring clutches and brakes, excluding the construction which can¡¦t configure the clutch and brake, establish the database can be configured. Finally, we determine a speed ratio for the eight-speed automatic transmissions, excluding the constructions doesn¡¦t match the appropriate gear ratios. Drawing the diagram which comply the restriction for eight-speed automatic transmissions. Keywords: automatic transmission, lever diagram, direct-member-number method, member number, configuration of clutches

An epicyclic-type automatic transmission is a device that is connected to the back of an engine and sends the power from the engine to the drive wheels. Its job is to keep the engine within a certain angular velocity. For the development of multi-speed parallel-connected automatic transmission for automobiles, the related configuration design methods are still tedious and prone to human error. Therefore, the purpose of this research is to present an efficient methodology for the systematic design of the parallel-connected automatic transmission for automobiles. First, fundamentals and gear-shifting operations of the parallel-connected automatic transmission are illustrated to establish the design requirements, and the theory of the analysis of speed ratios for epicyclic-type automatic transmission is derived based on the concept of lever analogy. Next, one simple clutching-sequence synthesis methods are proposed and illustrated, based on the lever analogy, and the design theory and the procedure of clutch configuration of epicyclic-type automatic transmission are developed. With the above methods, designs of six-speed and eight-speed parallel-connected automatic transmission. Finally, the complete atlas of six-speed and eight-speed parallel-connected automatic transmission can be systematically synthesized from the data of given speed ratios. This proposed design method can also be applied to the development and design of multi-speed parallel-connected automatic transmissions.

The characteristic staminal lever mechanism is defined as a functional unit including the modification of stamens into lever-like structures, their reversible movement and the organisation with the remaining floral structures and they are involved in the process of pollen transfer. The staminal levers play a major role in the process of pollen deposition on the pollinators&rsquo / body and their proportion and interaction with pollinators may have significant consequences for the pollination system in Salvia. In this study, staminal lever mechanism and floral diversity of bee pollinated species including Salvia absconditiflora, Salvia aethiopis, Salvia russellii, Salvia tchihatcheffii which grow sympatrically are investigated in the campus flora of Middle East Technical University. The functioning of the staminal lever mechanism is tested and pollinators of the Salvia species are observed by field investigations. Special attention is given to species-specific patterns of pollen deposition on the pollinators&rsquo / body. Floral diversity of the Salvia species such as corolla shape, size, colour, stamen type are studied. Floral and pollinator structures are measured morphometrically by laboratory investigations. Moreover, the isolation mechanism among the co-occuring Salvia species are investigated by field observations. All field observations are backed by photos and video recordings. Field and laboratory investigations revealed that co-occuring Salvia species are reproductively isolated by several means and the diversity of floral constructions and staminal lever mechanism increases the mechanical isolation by attracting different pollinators and by loading pollen on different parts of their bodies.