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Estudo da ação do laser de baixa intensidade sobre o recrutamento celular e os mediadores inflamatórios pulmonares na DPOC experimental em ratos / Low intensity laser action study on cell recruitment and pulmonary inflammatory mediators of experimental COPD in ratsAlves, Wellington dos Santos 26 February 2015 (has links)
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Previous issue date: 2015-02-26 / Introduction: One of the most common diseases in the present century, COPD (Chronic Obstructive Pulmonary Disease) has its mark on pulmonary inflammation, characterized by a number of cells such as macrophages, lymphocytes and neutrophils mainly degrading elastic fibers and release a series of inflammatory mediators that recruit other cells that act in defense in the lung. Objective: To develop a COPD model with passive inhalation of cigarette smoke in a 45 day period and promote the treatment of the disease with low-power laser. Methodology: the animals were organized into groups, control (breathing room air without cigarette smoke), the COPD group (45 days of passive inhalation of cigarette smoke) and Laser (45 days of passive inhalation + 15 days of application low power laser) .Results: Total and differential cell counts as well as histological and biochemical analysis shows the presence of COPD. Data from low-power laser-treated group shows that there was a reduction in the number of inflammatory cells and the concentration of the inflammatory mediators present in animal tissue in COPD. Conclusion: The passive inhalation of cigarette smoke for 45 days resulted in COPD, and the low-power laser was effective in the treatment because it took the reduction of inflammatory mediators and cells present in this lung disease. / Introdução: Uma das doenças mais comuns no século atual , a DPOC (Doença Pulmonar Obstrutiva Crônica) tem a sua marca na inflamação pulmonar, caracterizada por uma série de células como os macrófagos, linfócitos e principalmente os neutrófilos que degradam as fibras elásticas e liberam uma série de mediadores inflamatórios que recrutam outras células que atuam na defesa a nível pulmonar. Objetivo: desenvolver um modelo de DPOC com inalação passiva de fumaça de cigarro num período de 45 dias e promover o tratamento da doença com o laser de baixa potência. Metodologia: os animais foram organizados em grupos, o controle (respira o ar ambiente sem fumaça de cigarro), o grupo DPOC (45 dias de inalação passiva de fumaça de cigarro) e Laser (45 dias de inalação passiva + 15 dias de aplicação do laser de baixa potência). Resultados: A contagem total e diferencial das células, bem como as análises histológicas e bioquímicas mostra a presença da DPOC. Os dados do grupo tratado com laser de baixa potência mostra que houve redução do número de células inflamatórias e da concentração dos mediadores inflamatórios presentes na DPOC nos tecidos animais. Conclusão: A inalação passiva de fumaça de cigarro por 45 dias ocasionou a DPOC, e o laser de baixa potência foi eficaz no seu tratamento pois levou a redução dos mediadores inflamatórios e células presentes nesta doença pulmonar.
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Generation of compact test sets and a design for the generation of tests with low switching activityKumar, Amit 01 December 2014 (has links)
Test generation procedures for large VLSI designs are required to achieve close to 100% fault coverage using a small number of tests. They also must accommodate on-chip test compression circuits which are widely used in modern designs. To obtain test sets with small sizes one could use extra hardware such as test points or use software techniques. An important aspects impacting test generation is the number of specified positions, which facilitate the encoding of test cubes when using test compression logic. Fortuitous detection or generation of tests such that they facilitate detection of yet not targeted faults, is also an important goal for test generation procedures.
At first, we consider the generation of compact test sets for designs using on-chip test compression logic. We introduce two new measures to guide automatic test generation procedures (ATPGs) to balance between these two contradictory requirements of fortuitous detection and number of specifications. One of the new measures is meant to facilitate detection of yet undetected faults, and the value of the measures is periodically updated. The second measure reduces the number of specified positions, which is crucial when using high compression. Additionally, we introduce a way to randomly choose between the two measures.
We also propose an ATPG methodology tailored for BIST ready designs with X-bounding logic and test points. X-bounding and test points used to have a significant impact on test data compression by reducing the number of specified positions. We propose a new ATPG guidance mechanism that balances between reduced specifications in BIST ready designs, and also facilitates detection of undetected faults. We also found that compact test generation for BIST ready designs is influenced by the order in which faults are targeted, and we proposed a new fault ordering technique based on fault location in a FFR. Transition faults are difficult to test and often result in longer test lengths, we propose a new fault ordering technique based on test enumeration, this ordering technique and a new guidance approach was also proposed for transition faults. Test set sizes were reduced significantly for both stuck-at and transition fault models.
In addition to reducing data volume, test time, and test pin counts, the test compression schemes have been used successfully to limit test power dissipation. Indisputably, toggling of scan cells in scan chains that are universally used to facilitate testing of industrial designs can consume much more power than a circuit is rated for. Balancing test set sizes against the power consumption in a given design is therefore a challenge. We propose a new Design for Test (DFT) scheme that deploys an on-chip power-aware test data decompressor, the corresponding test cube encoding method, and a compression-constrained ATPG that allows loading scan chains with patterns having low transition counts, while encoding a significant number of specified bits produced
by ATPG in a compression-friendly manner. Moreover, the new scheme avoids periods of elevated toggling in scan chains and reduces scan unload switching activity due to unique test stimuli produced by the new technique, leading to a significantly reduced power envelope for the entire circuit under test.
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Politecast - a new communication primitive for wireless sensor networksLundén, Marcus January 2010 (has links)
Wireless sensor networks have the potential for becoming a huge market. Ericsson predicts 50 billion devices interconnected to the Internet by the year 2020. Before that, the devices must be made to be able to withstand years of usage without having to change power source as that would be too costly. These devices are typically small, inexpensive and severally resource constrained. Communication is mainly wireless, and the wireless transceiver on the node is typically the most power hungry component. Therefore, reducing the usage of radio is key to long lifetime. In this thesis I identify four problems with the conventional broadcast primitive. Based on those problems, I implement a new communication primitive. This primitive is called Politecast. I evaluate politecast in three case studies: the Steal the Light toy example, a Neighbor Discovery simulation and a full two-month deployment of the Lega system in the art gallery Liljevalchs. With the evaluations, Politecast is shown to be able to massively reduce the amount of traffic being transmitted and thus reducing congestion and increasing application performance. It also prolongs node lifetime by reducing the overhearing by waking up neighbors.
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Experimental Evaluation of the Feasibility of Wearable Piezoelectric Energy HarvestingJanuary 2020 (has links)
abstract: Technological advances in low power wearable electronics and energy optimization techniques
make motion energy harvesting a viable energy source. However, it has not been
widely adopted due to bulky energy harvester designs that are uncomfortable to wear. This
work addresses this problem by analyzing the feasibility of powering low wearable power
devices using piezoelectric energy generated at the human knee. We start with a novel
mathematical model for estimating the power generated from human knee joint movements.
This thesis’s major contribution is to analyze the feasibility of human motion energy harvesting
and validating this analytical model using a commercially available piezoelectric
module. To this end, we implemented an experimental setup that replicates a human knee.
Then, we performed experiments at different excitation frequencies and amplitudes with
two commercially available Macro Fiber Composite (MFC) modules. These experimental
results are used to validate the analytical model and predict the energy harvested as a function
of the number of steps taken in a day. The model estimates that 13μWcan be generated
on an average while walking with a 4.8% modeling error. The obtained results show that
piezoelectricity is indeed a viable approach for powering low-power wearable devices. / Dissertation/Thesis / Masters Thesis Electrical Engineering 2020
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Collaborative control of wave glider platforms - Local Communication and Sea State EstimationFangbemi, Kossivi Agbessi 28 February 2020 (has links)
Climate change is the focus of many oceanography and marine engineering researchers, with possible links between climate change and the carbon cycle in the Southern Ocean being considered. This type of investigation requires modern and cost-effective tools to conduct surveys and collect data from the ocean. The self-propelled unmanned surface vessel, the Liquid Robotics Wave Glider, was designed primarily as a marine research tool and offers several advantages over existing research vessels and other tools employed for data acquisition in the ocean. The main advantages are its robustness at sea, i.e. its ability to withstand extreme weather conditions, its propulsion energy source, which is the wave energy, and its customisable electronics payload. The inter-platform communication strategy of the Wave Glider inspired a few engineering questions, one of which is the focal point of this research: whether Low Power Wide Area Network (LPWAN) technology can be used to set up a local communication system enabling the collaboration of two or more Wave Gliders and reduce the cost, in terms of power and communication channels, involved in the communication with the Wave Glider platforms during missions. This research considers various LPWAN technologies available on the market and proposes LoRaWAN technology for the local communication system. LoRaWAN was selected as it presented a robust radio modulation and had growing support in the industry. In this research, a LoRa-based network of two nodes was developed, implemented and tested over the surface of the ocean. It was found that the system performs well over a distance of 1 km with both antennas having one end at the mean surface level of the sea. With the intention to increase the range of the platform and achieve a reliable and robust system, the research continued with the study of the influence of the surface waves on the proposed local communication system by exploring, firstly, the impact of seawater and, secondly, the wave height on signal transmission. The first study investigated the influence that the electromagnetic properties of seawater may have on the transmission of signals from one node to the second through simulations using the computational electromagnetic package FEKO. It revealed that, at the frequency of operation, which was 868 MHz, seawater reacted as a lossy conductor and reflected the signal upward, with negligible power penetrating the surface of the ocean. The subsequent study reviewed the statistical properties of the ocean surface waves in a sea of deep waters and proposed a relationship between the wind speed (or surface wave elevation), the antenna height, the distance separation between the two nodes and the probability of the presence of a line of sight (LoS) between the two nodes. This relationship quantifies the expected result that the probability of the LoS diminishes as the wind speed or the distance between the two nodes increases, whereas it improves with an increase in the antenna height. The last part of the research focused on initial works on sea state estimation using the lossless wave equation and Kalman Filter to provide 3D sea surface elevations that would be used to change to the probability of the LoS calculated previously in the research. Indeed, using the local communication to share the point-wise sea state data can be exploited to estimate the sea state over a rectangular region delimited to include these points. Sea state estimation is expected to enhance the joint navigation and coordination of the platforms and consequently, boost the probability of the LoS through the transmission at the crest of the waves. During the development of the Kalman Filter model, it was discovered that the sample time and the sample space significantly affect the performance and the stability of the discretised models. However, a carefully selected sampling time and sample space exhibited a stable system model. The results of the Kalman filtering were a realistic sea state estimate with a minimum error at the locations in the surrounding of the measurements.
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Energy-Efficient On-Chip Cache Architectures and Deep Neural Network Accelerators Considering the Cost of Data Movement / データ移動コストを考慮したエネルギー効率の高いキャッシュアーキテクチャとディープニューラルネットワークアクセラレータXu, Hongjie 23 March 2021 (has links)
付記する学位プログラム名: 京都大学卓越大学院プログラム「先端光・電子デバイス創成学」 / 京都大学 / 新制・課程博士 / 博士(情報学) / 甲第23325号 / 情博第761号 / 新制||情||130(附属図書館) / 京都大学大学院情報学研究科通信情報システム専攻 / (主査)教授 小野寺 秀俊, 教授 大木 英司, 教授 佐藤 高史 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM
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Návrh DDA zesilovače pro zpracování biologických signálů / Design of differential difference amplifier (DDA) for biological signals processingGrochal, Peter January 2021 (has links)
The work deals with the analog design of low-voltage and low-power differential difference amplifier DDA with adaptive differential input stage, second stage class AB, improved by a self – cascode to achieve higher gain and slew rate. Conventional and unconventional techniques, and methods for low-voltage and low-power design are presented. The finished design of the differential difference amplifier DDA with the analyzed results is presented. Design of a Butterwortho low-pass filter of the sixth order based on DDA with Sallen Key topology and design of a multifunctional ARC filter based on DDA.
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Viewer-Aware Intelligent Mobile Video System for Prolonged Battery LifeGao, Peng January 2017 (has links)
In the modern society, mobile is gradually going to become all about video streaming. The main reasons of video growth are mobile devices such as smartphones and tablets which enable people to have access to videos they would like to watch at anywhere and anytime. However, due to the large video data size and intensive computation, video processing leads to a huge power consumption. Mobile system designers typically focus on hardware-level power optimization techniques without considering how hardware performance interfaces with viewer experience. In my research, I investigated how viewing context factors affect mobile viewing experience. Furthermore, a viewer-aware intelligent mobile video system was designed to optimize power efficiency automatically in real-time according to the viewing context and maintain the same viewing experience. Our research opened a door for developments of future viewer-aware mobile system design, accelerating low-cost mobile devices with longer battery life.
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Efficient Bi-Directional Communications for Low-Power Wireless Mesh Network / 低消費電力無線メッシュネットワークにおける高能率双方向通信Okumura, Ryota 23 March 2021 (has links)
京都大学 / 新制・課程博士 / 博士(情報学) / 甲第23328号 / 情博第764号 / 新制||情||130(附属図書館) / 京都大学大学院情報学研究科通信情報システム専攻 / (主査)教授 原田 博司, 教授 守倉 正博, 教授 大木 英司 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM
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Non-Planar Nanotube and Wavy Architecture Based Ultra-High Performance Field Effect TransistorsHanna, Amir 11 1900 (has links)
This dissertation presents a unique concept for a device architecture named the nanotube (NT) architecture, which is capable of higher drive current compared to the Gate-All-Around Nanowire architecture when applied to heterostructure Tunnel Field Effect Transistors. Through the use of inner/outer core-shell gates, heterostructure NT TFET leverages physically larger tunneling area thus achieving higher driver current (ION) and saving real estates by eliminating arraying requirement. We discuss the physics of p-type (Silicon/Indium Arsenide) and n-type (Silicon/Germanium hetero-structure) based TFETs. Numerical TCAD simulations have shown that NT TFETs have 5x and 1.6 x higher normalized ION when compared to GAA NW TFET for p and n-type TFETs, respectively. This is due to the availability of larger tunneling junction cross sectional area, and lower Shockley-Reed-Hall recombination, while achieving sub 60 mV/dec performance for more
than 5 orders of magnitude of drain current, thus enabling scaling down of Vdd to 0.5 V.
This dissertation also introduces a novel thin-film-transistors architecture that is named the Wavy Channel (WC) architecture, which allows for extending device width by integrating vertical fin-like substrate corrugations giving rise to up to 50% larger device width, without occupying extra chip area. The novel architecture shows 2x higher output drive current per unit chip area when compared to conventional planar architecture. The current increase is attributed to both the extra device width and 50% enhancement in
field effect mobility due to electrostatic gating effects. Digital circuits are fabricated to demonstrate the potential of integrating WC TFT based circuits. WC inverters have shown 2× the peak-to-peak output voltage for the same input, and ~2× the operation frequency of the planar inverters for the same peak-to-peak output voltage. WC NAND circuits have shown 2× higher peak-to-peak output voltage, and 3× lower high-to-low propagation delay times when compared to their planar counterparts. WC NOR circuits have shown 70% higher peak-to-peak output voltage, over their planar counterparts. Finally, a WC based pass transistor logic multiplexer circuit is demonstrated, which has shown more than 5× faster high-to-low propagation delay compared to its planar counterpart at a similar peak-to-peak output voltage.
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