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41	The Influence of Spatial Attention on Neuronal Receptive Field Structure within Macaque Area MT / Der Einfluss von räumlicher Aufmerksamkeit auf die Struktur rezeptiver Felder im superior-temporalen Kortex des Rhesusaffen Womelsdorf, Thilo 04 November 2004 (has links) No description available. 570 Biowissenschaften, Biologie Mathematics and Computer Science Aufmerksamkeit rezeptives Feld Primaten Wahrnehmung Bewegung visuelles System Elektrophysiologie Area MT Parietallappen Krosskorrelation Kortex attention receptive field primates perception motion vision visual system electrophysiology area MT parietal cortex reverse correlation cortex 42.63 77.37 77.40 WA 000: Biologie WA 700: Systeme in der Biologie FI 000: Psychologie: Sonstiges
42	Development of nonsymmetrical 1,4-disubstituted anthraquinones that are potently active against cisplatin-resistant ovarian cancer cells Teesdale-Spittle, P.H., Pors, Klaus, Brown, R., Patterson, Laurence H., Plumb, J.A. January 2005 (has links) No / A novel series of 1,4-disubstituted aminoanthraquinones were prepared by ipso-displacement of 1,4-difluoro-5,8-dihydroxyanthraquinones by hydroxylated piperidinyl- or pyrrolidinylalkyl-amino side chains. One aminoanthraquinone (13) was further derivatized to a chloropropyl-amino analogue by treatment with triphenylphosphine-carbon tetrachloride. The compounds were evaluated in the A2780 ovarian cancer cell line and its cisplatin-resistant variants (A2780/ cp70 and A2780/MCP1). The novel anthraquinones were shown to possess up to 5-fold increased potency against the cisplatin-resistant cells compared to the wild-type cells. Growth curve analysis of the hydroxyethylaminoanthraquinone 8 in the osteosarcoma cell line U-2 OS showed that the cell cycle is not frozen, rather there is a late cell cycle arrest consistent with the action of a DNA-damaging topoisomerase II inhibitor. Accumulative apoptotic events, using time lapse photography, indicate that 8 is capable of fully engaging cell cycle arrest pathways in G2 in the absence of early apoptotic commitment. 8 and its chloropropyl analogue 13 retained significant activity against human A2780/cp70 xenografted tumors in mice. Treatment resistance Transition metal Complexes Divalent metal Complexes Platinum II Complexes Malignant tumour Alkylating agent Vertebrata Mammalia Rodentia Cell line Chlorine Organic compounds Animal Ovary Tumour cell Human Alcohol Antineoplastic agent Mechanism of action Antimitotic Intraperitoneal administration Chemotherapy Cytotoxicity In vivo Pyrrolidine derivatives Piperidine derivatives Tricyclic compound Condensed benzenic compound Structure activity relation Diphenols Aromatic amine Ovarian cancer In vitro Chemical synthesis Cisplatin
43	Klonierung und Charakterisierung des Interleukin-1beta-Systems im Gehirn von Callithrix jacchus / Cloning and characterization of the interleukin-1beta-system in the brain of Callithrix jacchus Köster-Patzlaff, Christiane 03 July 2003 (has links) No description available. 570 Biowissenschaften, Biologie Mathematics and Computer Science Lipopolysaccharid RT-PCR in-situ-Hybridisierung Immunhistologie Hippocampus Claustrum Cortex IL-1ra IL-1RI IL-1RII Lipopolysaccharid RT-PCR in-situ-Hybridization Immunhistology Hippocampus Claustrum Cortex IL-1ra IL-1RI IL-1RII 42.13 Molekularbiologie 42.60 Zoologie: Allgemeines 42.63 Tierphysiologie 42.84 Mammalia WA WF WH
44	Determinants of population structure in the world's smallest primate, <i>Microcebus berthae</i>, across its global range in Menabe Central, Western Madagascar / Determinanten der räumlichen Populationsstruktur des kleinsten bekannten Primaten, <i>Microcebus berthae</i>, in dessen globalem Verbreitungsgebiet Menabe Central, West-Madagaskar Schäffler, Livia 16 December 2011 (has links) No description available. 570 Biowissenschaften Biologie räumliche Verteilung ökologische Struktur Populationsdynamik Koexistenz Gemeinschaft nahverwandte Arten interspezifische Interaktion Konkurrenz Prädation Mausmaki Artenschutz Biodiversität distribution ecological structure population dynamics species assemblage congener coexistence interspecific interaction competition predation <i>Microcebus</i> biodiversity conservation 42.65 Tiergeographie Tierökologie 42.84 Mammalia Primatenkunde 43.31 Naturschutz Artenschutz 43.70 Entwicklungsländer und Umwelt Artenschutz WXR 000 Tierökologie WXU 000 Populationsdynamik Tiergeographie WXU 100 Faunen

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