Dans le cadre de la simulation numérique portant sur la prédiction de phénomènes complexes, la modélisation de la pénétration d’un corps à travers un solide reste un challenge. Ceci est d’autant plus vrai si le corps impacté comporte une épaisseur importante devant les dimensions du projectile. Notamment, dans le contexte de la biomécanique des chocs, l’investigation des traumatismes suite à une blessure par balle, par un moyen numérique, nécessite la modélisation d’une zone pouvant être de plusieurs dizaines de fois supérieure aux dimensions du projectile sur un temps extrêmement court (de l’ordre de quelques dixièmes de milli-seconde). Les méthodes numériques dites classiques comme les éléments finis sont limitées dans ce domaine, dû en particulier à des problèmes de distorsions de maillage. Ce travail de thèse tente donc d’apporter une contribution dans le cadre de la modélisation des impacts pénétrants en proposant l'utilisation d’une méthode alternative sans maillage, la méthode "Smoothed Particle Hydrodynamics" (SPH).Méthode "Smoothed Particle Hydrodynamics, Impact Pénétrant, Biomécanique, Dynamique Rapide, Axisymétrie / Numerical simulation offers the possibility to investigate complexe phenomenons by giving access to useful informations about the evolution of a material system under constraints. Nevertheless, there are some situations where classical procedures, such as the Finite Elements Method (FEM), suffers from issues (e.g. mesh distorsions). One of these situations comes from a biomechanical context, where the investigation tends to observe the penetration of a projectile through human soft tissus. In this context, the objective of this Ph.D Thesis is to evaluate the capability of one alternative method, named Smoothed Particle Hydrodynamics method (SPH), to handle such modelling configurations.Smoothed Particle Hydrodynamics method, Penetrating Impact, Biomechanics, Fast Dynamics, Axis-symmetry

The aim of this thesis has been to investigate the benefits, pitfalls and possibilities of using geophysical methods in archaeological projects. This is exemplified by surveys carried out at archaeological sites in different geographical and chronological contexts. The thesis also aims at investigating the cause for the under-use of the methods in Swedish archaeology by looking at previously conducted surveys. The methods used during these surveys have been Ground-penetrating radar (GPR), magnetometer, slingram and a kappameter. The surveys in the mountain tundra region of Lapland show that magnetic susceptibility surveys is a valuable aid in discovering heaps of fire-cracked stones and when combined with magnetometry, also hearths. GPR and magnetometer surveys within the Migration Period ringfort Sandbyborg provided the spatial layout of the fort and indicated, along with results from recent excavations and metal detections, many similarities with the ringfort Eketorp II. The non-magnetic character of the sedimentary bedrock on Öland and Gotland is suitable for magnetometer surveys and the method is also highly appropriate for the detection of the remains of high-temperature crafts. GPR surveys at St. Mary’s Dominican convent in Sigtuna produced the spatial layout of the central cloister area. The investigations also show that the geology, pedology, land use and the character of commonly occurring prehistoric remains in Sweden, in certain circumstances and in certain areas, have restricted the possibility of successfully carrying out geophysical surveys. Care must therefore be taken to choose the right instrument for the survey and to tailor the sampling density of each geophysical survey, according to the character and size of the expected archaeological remains, in order to maximize their information return. To increase the use of geophysical methods in Sweden the educational opportunities, both for surveyors and professional archaeologists, need to improve. / <p>At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 2: Submitted. Paper 3: Manuscript.</p>

Ground penetrating radar (GPR) systems are increasingly being used for the detection and location of buried objects within the upper regions of the earth’s surface. The antenna is the most critical component of such a system. This thesis presents a comprehensive study of resistor-loaded planar dipole antennas for GPR applications using both theory and experiments. The theoretical analysis is performed using the finite difference time domain (FDTD) technique. The analysis starts with the most popular planar dipole, the bow-tie. A parametric study is done to find out how the flare angle, length, and lumped resistors of the antenna should be selected to achieve broadband properties and good target detection with less clutter. The screening of the antenna and the position of transmitting and receiving antennas with respect to each other and ground surface are also studied. A number of other planar geometrical shapes are considered and compared with the bow-tie in order to find what geometrical shape gives the best performance. The FDTD simulations are carried out for both lossless and lossy, dispersive grounds. Also simulations are carried out including surface roughness and natural clutter like rocks and twigs to make the modeling more realistic. Finally, a pair of resistor-loaded bow-tie antennas is constructed and both indoor and outdoor measurements are carried out to validate the simulation results. / <p>QC 20100923</p>

The terms &lsquo / ground-probing radar&rsquo / , &lsquo / ground penetrating radar (GPR)&rsquo / , &lsquo / sub-surface radar&rsquo / or &lsquo / surface-penetrating radar (SPR)&rsquo / refer to various techniques for detecting and imaging of subsurface objects. Among those terms GPR is preferred and used more often. In this thesis, the depth and the position of the buried circular cylinder are determined by a GPR system which comprises of an optical fiber sensor (OFS). The system is a combination of OFS, GPR and optical communication link. In order to determine the depth and the position, first of all the electric field distribution at the OFS is obtained by integrating the Green&rsquo / s function over the induced current distribution. Those distributions are observed for different frequency and depth values. The voltages inside the distribution are measured by OFS. By changing the depth of the cylinder and the frequency of the system, various plots showing x axis displacement versus measured voltages are obtained. Those plots are related to interference fringe patterns. The position and the depth of the cylinder are obtained using interference fringe patterns. All of the studies mentioned are performed in MATLAB R2007b program. The noises of the system due to OFS are extracted using OPTIWAVE OPTISYSTEM 7.0 program. By adding those noises to the measured voltage values, the operating frequency of the system is observed.

Several studies suggest that deep convection that penetrates the tropical tropopause layer may influence the long-term trends in lower stratospheric water vapor. This thesis investigates the relationship between penetrating deep convection and lower stratospheric water vapor variability using historical infrared (IR) observations. However, since infrared observations do not directly resolve cloud vertical structure and cloud top height, and there has been some debate on their usefulness to characterize penetrating deep convective clouds, CloudSat/Calipso and Aqua MODIS observations are first combined to understand how to best interpret IR observations of penetrating tops. The major findings of the combined CloudSat/Calipso and Aqua MODIS analysis show that penetrating deep convection predominantly occur in the western tropical Pacific Ocean. This finding is consistent with IR studies but is in contrast to previous radar studies where penetrating deep convective clouds predominantly occur over land regions such as equatorial Africa. Estimates on the areal extent of penetrating deep convection show that when using IR observations with a horizontal resolution of 10 km, about two thirds of the events are large enough to be detected. Evaluation of two different IR detection schemes, which includes cold cloud features/pixels and positive brightness temperature differences (+BTD), show that neither schemes completely separate between penetrating deep convection and other types of high clouds. However, the predominant fraction of +BTD distributions and cold cloud features/pixels ≤ 210 K is due to the coldest and highest penetrating tops as inferred from collocated IR and radar/lidar observations. This result is in contrast to previous studies that suggest the majority of cold cloud features/pixels ≤ 210 K are cirrus/anvil cloud fractions that coexist with deep convective clouds. Observations also show that a sufficient fraction of penetrating deep convective cloud tops occur in the extratropics. This provides evidence that penetrating deep convection should be documented as a pathway of stratospheric-tropospheric exchange within the extratropical region. Since the cold cloud feature/pixel ≤ 210 K approach was found to be a sufficient method to detect penetrating deep convection it was used to develop a climatology of the coldest penetrating deep convective clouds from GridSat observations covering years 1998-2008. The highest frequencies of the coldest penetrating deep convective clouds consistently occur in the western-central Pacific and Indian Ocean. Monthly frequency anomalies in penetrating deep convection were evaluated against monthly anomalies in lower stratospheric water vapor at 82 mb and show higher correlations for the western-central Pacific regions in comparison to the tropics. At a lag of 3 months, the combined western-central Pacific had a small but significant anticorrelation, where the largest amount of variance explained by the combined western-central Pacific region was 8.25%. In conjunction with anomalies in the 82 mb water vapor mixing ratios, decreasing trends for the 1998-2008 period were also observed for tropics, the western Pacific and Indian Ocean. Although none of these trends were significant at the 95% confidence level, decreases in the frequency of penetrating deep convection over the 1998-2008 shows evidence that could explain in part some of the 82 mb lower stratospheric water vapor variability.

Rock glaciers play a significant role in the alpine debris transport system. For practical and engineering considerations, identifying the internal structure and its relationship to surface characteristics is significant in terms of how a rock glacier settles during periods of melting, and the mode of deformation. A better understanding of these factors is important for engineers, engineering geologists and geomorphologists who must make prudent evaluations of rock glaciers as potential sites for human development and uses. It is equally important for evaluating potential stores for water on other planets such as Mars. Ground penetrating radar (GPR) shows that the internal structure of a lobate rock glacier located in the San Juan Mountains of southwest Colorado consists of continuous to semi-continuous horizontal layers of ice-supersaturated sediments and coarse blocky rockslide debris which likely formed through catastrophic episodes of rockfall from the cirque headwall. Folds in the uppermost layers correspond to the surface expression of ridges and furrows, indicating that compressive stresses originating in the steep accumulation zone are transmitted downslope through the rock glacier. The rock glacier is a composite feature that formed by a process involving the development and overlap of discrete flow lobes that have overridden older glacial moraine and protalus rampart materials. The latter materials have been incorporated into the present flow structure of the rock glacier. The discovery of rock glacier-like features on Mars suggests the presence of flowing, or once-flowing ice-rock mixtures. These landforms, which include lobate debris aprons, concentric crater fill and lineated valley fill, hold significant promise as reservoirs of stored water ice that could be used as fuel sources for human exploration of Mars and provide a frozen record of the climatic history of the planet. To this end, the rock glacier in this study was used as a surrogate for similar Martian landforms. Liquid water, found to be abundant in this rock glacier, occurs within a network of interconnected channels that permeate throughout the landform. In terms of water storage within Martian analogs, consideration must include the possibility that some water ice may be stored in relatively pure form within lenses and vein networks that are supplied by seasonal frost accumulation and/or water influx from below.

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Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal

La mitochondrie fournit l'énergie nécessaire au fonctionnement cellulaire, grâce au mécanisme de phosphorylation oxydative. Cette fonction nécessite une expression coordonnée des génomes nucléaires et mitochondriaux assurée par la famille de coactivateurs transcriptionnels PGC-1 (Peroxisome proliferator-activated receptor γ Coactivator-1), sensibles aux signaux endogènes et/ou environnementaux. Une régulation plus fine de la phosphorylation oxydative par des miRNAs est maintenant soupçonnée. Afin de préciser ces différents modes de régulation dans des modèles cellulaires de carcinomes thyroïdiens, nous avons exploré la voie PRC-dépendante (PGC-related coactivator) et les miRNAs spécifiquement exprimés dans ces modèles présentant une richesse en mitochondries et des niveaux de PRC et de PGC-1α différents. Ce travail a permis de mettre en évidence miR-218 comme marqueur clé de régulation de la fonction mitochondriale. Au-delà de la régulation de l'expression génique, une fourniture énergétique adéquate nécessite également une répartition optimale des mitochondries au sein de la cellule, grâce à d'étroites connexions entre le cytosquelette et la mitochondrie. Des peptides issus de la sous-unité légère des neurofilaments, dont le NFL-TBS.40-63, sont capables d'entrer spécifiquement dans les cellules de glioblastomes humains et d'y déstabiliser le réseau microtubulaire, conduisant à la mort cellulaire par apoptose. Pour étudier l'impact de ce peptide sur le réseau de mitochondries et leurs fonctions, nous avons traité le modèle cellulaire de glioblastomes humains T98G, par différentes concentrations de NFL-TBS.40-63. Ce travail révèle une perturbation du réseau de mitochondries et une diminution de la respiration mitochondriale dans les cellules exposées. L'ensemble de ces travaux doit permettre le développement de traitements ciblés de la fonction mitochondriale.