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Diagnóstico da síndrome pré-menstrual : comparação de dois instrumentos - registro diário da intensidade dos problemas (DRSP) e instrumento de rastreamento de sintomas pré-menstruais (PSST)Henz, Aline January 2016 (has links)
Introdução: O diagnóstico da Síndrome Pré-menstrual (SPM) é um desafio. O uso de questionários estruturados está bem estabelecido, e a ferramenta mais aceita é o DRSP, um questionário prospectivo auto preenchido por ao menos dois meses. O PSST é um questionário retrospectivo de autoaplicação, preenchido em um único momento. Objetivo: comparar estes dois instrumentos (PSST e DRSP) para o diagnóstico da SPM. Método: Um estudo transversal com 127 mulheres entre 20 a 45 anos com queixas de SPM. As mulheres foram avaliadas quanto ao peso, altura, Índice de Massa Corporal (IMC). Após exclusão de casos de depressão através do Prime-MD, as pacientes completaram o PSST e foram orientadas a preencherem o DRSP durante dois meses. A concordância entre os dois questionários foi avaliado pelo cálculo de Kappa (k) e valores do coeficiente PABAK. Resultados: Do total de mulheres que atenderam ao chamado, 282 (74%) preencheram os critérios de elegibilidade e responderam o PSST. Entre estas 282 mulheres, somente 127 (45%) completaram o questionário diário (DRSP) por dois ciclos. O percentual das mulheres com diagnóstico de SPM através do DRSP foi de 74,8%, e pelo PSST foi 41,7%. O percentual das mulheres com diagnóstico de TDPM pelo DRSP foi de 3,9%, e pelo PSST foi de 34,6%. Assim, verificou-se uma maior prevalência de SPM com o DRSP do que com o PSST. De outra parte a TDPM foi mais dignosticada pelo PSST do que com o DRSP. O número de pacientes consideradas “normais” foi semelhante com os dois instrumentos. Na avaliação entre os dois instrumentos verificou-se não haver nenhuma concordância (Kappa = 0,12) nos resultados do diagnóstico de SPM e TDPM (Coeficiente Pabak resultou = 0,39). Para a trigem de SPM/TDPM o PSST tem uma sensibilidade de 79% e especificidade de 33,3%. Conclusão: O PSST deve ser considerado como uma ferramenta de triagem diagnóstica. Conclui-se que os casos SPM/TDPM do PSST devem ser sempre melhor avaliados pelo DRSP. / Background: The diagnosis of Premenstrual Syndrome (PMS) is a challenge. The use of structured questionnaires is well established and the most accepted is the DRSP, a prospectively self-administered questionnaire that needs two months at least to be completed. The PSST is a retrospective self-scale questionnaire, filled at a single time. Aim: To compare these two instruments (PSST and DRSP) to diagnosis PMS. Methods: A cross-sectional study with 127 women between 20 and 45 years with PMS complaints. The women were evaluated about weight, high, Body Mass Index (BMI). After the exclusion of depression by the Prime-MD Questionnaire, the PSST was completed and the women were oriented to complete the DRSP for two months. The agreement between the two questionnaires was assessed by calculating the Kappa (k) and PABAK values. Results: 282 (74% of all the women) women met eligibility criteria and answered the PSST. Only 127 (45% of the 282 women) completed the daily questionnaire (DRSP) for two cycles. The percentual of women with PMS diagnosis by the DRSP was 74.8%, and by PSST was 41.7%. The percentual of women with PMDD diagnosis by the DRSP was 3.9%, and by the PSST was 34.6%. The number of patients considered “normal” (with the symptoms above the necessary for the diagnostic the PMS) was similar with both questionnaires. We found no agreement between the two instruments (Kappa = 0.12) in the diagnosis of PMS and PMDD (Pabak coefficient keep this result = 0.39). For screening PMS/PMDD the PSST has a sensitivity of 79% and a specificity 33.3%. Conclusion: The PSST should be considered as diagnostic screening tool. We concluded that positive PMD/PMDD cases of PSST should be ever better evaluated by DRSP.
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Síndrome pré-menstrual : relação entre a intensidade dos sintomas e a reserva ovarianaOderich, Carolina Leão January 2017 (has links)
Introdução. A Síndrome Pré-menstrual (SPM) é caracterizada por sintomas de estresse somáticos e comportamentais que se desenrolam logo após a ovulação, atingindo um pico máximo próximo à data da menstruação e desaparecendo em média em até quatro dias após o início do sangramento. A presença da formação do corpo lúteo seria necessária para a presença dos sintomas, contudo essa dinâmica dos hormônios da fase lútea associados à SPM é pouco conhecida. O hormônio antimülleriano (HAM) é um dos melhores marcadores de declínio da capacidade reprodutiva das mulheres. Até o momento o mesmo não foi correlacionado a sintomas da SPM. A percepção de piora dos sintomas da SPM na perimenopausa é sugerida, existindo a possibilidade de que com a menor função ovariana (redução do HAM) exista uma exacerbação da SPM durante essa fase da vida reprodutiva da mulher. Objetivo: avaliar o padrão de SPM em mulheres com idade superior a 35 anos e correlacionar seus sintomas com a redução de HAM. Métodos: Estudo observacional, transversal, com uma amostra de conveniência composta por mulheres recrutadas através da mídia local. O questionário Registro Diário da Intensidade de Problemas (DRSP) de 2 meses foi utilizado para o diagnóstico de SPM. As participantes (N = 101) foram avaliadas em seus perfis antropométricos (peso, altura, índice de massa corporal) e social (paridade, nível educacional, uso de contracepção oral). Depois de completar o questionário DRSP por 2 meses, as mulheres retornaram no período prémenstrual para a coleta do sangue. Entre as participantes que utilizaram contracepção hormonal, foi solicitado um período de wash out de um mês para a coleta de sangue e dosagem de HAM no soro. O HAM foi analisado usando um kit comercial ELISA, de acordo com as instruções do fabricante. A análise estatística foi realizada na versão SPSS 18.0. O nível de significância adotado para todas as análises foi estabelecido em 5%. Resultados: A análise de HAM mostrou uma redução significativa após a idade de 35 anos, e não foi relacionada à severidade dos sintomas de SPM. Os sintomas físicos na fase lútea, mas não os emocionais, foram maiores em mulheres com mais de 35 anos de idade. A análise de Spearman mostrou uma correlação positiva entre um grupo de ≥35 anos e uma correlação negativa entre o uso de contracepção oral com piora dos sintomas físicos da SPM. Conclusão: este estudo mostrou que não houve piora dos sintomas emocionais entre as mulheres com SPM após os 35 anos de idade, apenas piora dos sintomas físicos, que necessitam uma investigação mais aprofundada. Não há relação entre os sintomas físicos e emocionais com níveis de HAM nas mulheres com SPM. / Background. Premenstrual Syndrome (PMS) is characterized by somatic and behavioral stress symptoms that take place soon after ovulation, reaching a peak near the time of menstruation and disappears on average within 4 days after the start of the bleeding. The presence of the corpus luteum formation would be needed for the presence of symptoms, however, these dynamics luteal phase of hormones associated with PMS is not well known. The anti-müllerian hormone (AMH) is one of the best markers of decline in women's reproductive capacity, and AMH has not been correlated with PMS symptoms. The perception of worsening of PMS symptoms in perimenopause is suggested, with the possibility that with less ovarian reserve (reduction of AMH) there is an exacerbation of PMS during this phase of the woman's reproductive life. Objective: To evaluate the pattern of PMS in women aged over 35 years, and correlate its symptoms to the reduction of AMH. Methods: It was an observational, cross-sectional study with a convenience sample composed of women recruited through local media. The 2-months DRSP questionnaire was used for PMS diagnosis. The participants (N=101) were evaluated in their anthropometric (weight, height, body mass index) and social (parity, educational level, use of oral contraception) profiles. After completing the DRSP questionnaire for 2 months, women returned in the pre-menstrual period for serum collection. Among participants using hormonal contraception, a one-month washout period was requested for serum collection and AMH dosage. AMH was analyzed using an ELISA commercial kit, according the manufacturer’s instructions. Statistical analysis was carried out in SPSS version 18.0. Significance level adopted for all analyzes was set at 5%. Results: AMH analysis showed a significant reduction after the age of 35 years, and it was not related to PMS symptoms severity. Physical symptoms in luteal stage were greater in women aged over 35 years, emotional symptoms were equal in both ages. Spearman’s analysis showed a positive correlation between ≥ 35years group and a negative correlation between the use of oral contraception with PMS physical symptoms worsening. Conclusion: this study showed that there is no worsening of emotional symptoms among women with PMS after 35 years of age, with a greater physical complaint, that needs further investigation. There is no relation between the physical and emotional symptoms with AMH levels in PMS women.
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The effects of Hypericum perforatum with Vitex agnus-catus in the treatment of menopausal symptomsvan Die, Margaret Diana, diana.vandie@rmit.edu.au January 2009 (has links)
Background: Interest in alternatives to hormone therapy (HT) for menopausal symptoms increased following its association with serious health risks. In terms of phytotherapeutic interventions, while traditional use supports a range of herbs for treating menopausal symptoms, evidence from rigorous scientific trials is limited, and has largely focused on the phytoestrogenic plants. Because of some safety concerns over long-term use of isoflavones, the present study focused on two non-estrogenic herbs, Hypericum perforatum and Vitex agnus-castus, also employed in this context in the Anglo-American and European traditions. Both herbs have shown effectiveness for the alleviation of symptoms of premenstrual syndrome (PMS), which is reported to be more severe during the perimenopause, and may account for many of the so-called 'menopausal symptoms' at this time. Research on menopausal vasomotor symptoms is prone to substantial placebo responses. There has been much interest in increasing our understanding of the placebo response with a view to controlling it in clinical research and harnessing it in clinical practice. Methods & Results: A double-blind, randomised controlled trial (RCT), with a 16-week treatment phase, was conducted on 100 late-perimenopause and early postmenopause women. The herbal combination (Hypericum and Vitex) was not found to be superior to placebo for any of the endpoints - daily weighted flushing scores, overall menopausal symptoms (on the Greene Climacteric Scale) and depression (on the Hamilton Depression Inventory). However, significant improvements across the treatment phase were observed in both arms for all of these outcome measures. No significant change was found for either group on the Utian quality of life scale. The effects of the herbal combination were also examined on PMS-like symptoms in the small sub-population of late-perimenopausal women, and found to be superior to placebo for total PMS-like symptoms and the sub-clusters, PMS-D (depression) and PMS-C (cravings). The active treatment group also showed significant improvements on PMS-A (anxiety) and PMS-H (hydration), although these effects were not superior to placebo. Predictors of the placebo response were investigated and found to include study-entry anxiety for the outcome measures of flushing, depression and overall menopausal symptoms, and improvement during non-treatment run-in for depression and overall symptoms. Because no difference had been found between 'active' and placebo groups in the menopause RCT, it was hypothesised that the same predictors would predict the response to the study treatment. However, low anxiety was significantly associated with improvement in this group. None of the other variables that predicted the placebo response was relevant to the study treatment response. This finding is discussed with reference to the possibility that 'drug' effects and placebo effects are not necessarily additive, and that the same magnitude of effect in both arms might not necessarily imply activity via the same pathways. Conclusions: This research contributes to the growing body of scientific knowledge about evidence-based complementary therapies that informs the community, health-care providers and regulatory authorities. The findings may facilitate identification of potential placebo responders in future research. The need for more research in the area of mechanisms of placebo versus active responses is supported.
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The nearby young [special character] Chamaeleontis cluster as a laboratory for star formation and evolutionLyo, A-Ran, Physical, Environmental & Mathematical Sciences, Australian Defence Force Academy, UNSW January 2004 (has links)
[Special characters cannot be displayed. Please see the pdf version of the Abstract for an accurate reproduction.] We studied the circumstellar discs, the initial mass function (IMF), mass distribution, binarity and the fundamental properties of the [special character] 9 Myr-old pre-main sequence (PMS) [special character] Chamaeleontis cluster. Using JHKL colour-colour and colour-excess diagrams, we found the circumstellar disc fraction to be [special character] 0.60 among the late-type members. Four stars with [special character] (K - L) > 0.4 were identified as experiencing ongoing accretion which was later confirmed by high-resolution spectroscopic study. Quantitative analysis of the H[special character] profiles found accretion in these four stars at rates comparable to that of two members of the similarly-aged TW Hydrae Association (TWA); rates 1 - 3 orders of magnitude lower than in younger classical T Tauri stars. Together these results suggest that, while the mass accretion rate decreases with age, PMS stars can retain their inner discs for [special character] 10 Myr. An optical photometric survey spanning 1.3 ?? 1.3 pc added two low-mass stars to the cluster inventory. Together with other recent surveys the population is likely to be significantly complete for primaries with masses M > 0.15M[special character]. The cluster now consists of 18 primaries and 9 confirmed and candidate secondaries, with [special character] 2-4 times higher multiplicity than seen in field dwarfs. The cluster IMF is consistent with that of rich young clusters and field stars. By extending the IMF to lower masses, we predict 20-29 low-mass stars and brown dwarfs may remain undiscovered. From study of the cluster???s spatial and mass distribution, we find the [special character] Cha cluster has significant mass segregation, with > 50 per cent of the stellar mass residing within the central 0.17 pc. Lastly we classified members of the cluster with low-resolution spectra, providing information about the fundamental properties of the PMS stars by comparison to standard dwarfs. Broadband VRI colours and pseudocontinuum indices derived for the cluster stars are indistinguishable from dwarfs at visual and red wavelengths. This suggests the temperature sequence for the PMS [special character] Cha cluster is similar to that of the dwarf sequence. Narrow-band spectral indices for the [special character] Cha cluster possibly indicate higher metallicity and strongly indicate lower surface gravity than the dwarf indices.
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Nucléosynthèse dans les étoiles de la branche asymptotique: du coeur dégénéré à l'envellope circumstellaireDUFOUR, Emmanuel 17 February 2000 (has links) (PDF)
Les étoiles de la branche asymptotique (AGBS) sont surtout connues pour deux faits historiques: - le "mystère des éléments s": riches en neutrons et possédant une durée de vie inférieure à celle des AGBS, ces éléments sont néanmoins présents dans les enveloppes de ces étoiles. De plus, les abondances de ces éléments "s" sont mal reproduites par les modèles existants. - le "mystère des étoiles carbonées": ces étoiles, dont les abondances vérifient C/O>1, sont majoritairement de faible luminosité. C'est un drainage (DUP) qui permet aux AGBS de devenir carbonées: l'enveloppe convective (CE) descend là où brûle 1H et prélève du Carbone, produit plus bas par la combustion de 4He et amené là par des languettes convectives récurrentes, les pulses thermiques. Or, les profondeurs des DUP modélisés pour des AGBS de faibles masses n'expliquent la forte proportion de Carbone observée. Ces deux mystères conduisent à identifier deux paramètres majeurs de l'évolution des abondances: la perte de masse et le DUP. Le premier contrôle la fin de la phase AGB et la température à la base de la CE, à masse stellaire fixée. Le deuxième maîtrise l'apport de protons entre les couches de 1H et de 4He et la modification des abondances de surface. Et c'est de la physique non standard qui est sous-jacente à ces paramètres: couplage gaz-poussière, pulsations, ondes de chocs, dégénérescence, convection avec gradient de composition, mélange non standard (non thermiquement induit)... Plusieurs études ayant été faites, tant sur les mécanismes de production que sur le paramétrage de la perte de masse, ce travail est centré sur l'influence du traitement du DUP sur la nucléosynthèse des AGBS de masses intermédiaires. La nucléosynthèse étant connue grâce à une coopération étroite entre méthodes observationnelles et théoriques, cette thèse a été menée sur les deux fronts. Cela rend possible "l'éclairage" de chacune des méthodes par les forces et les faiblesses de l'autre et donc de mieux évaluer la fiabilité d'une mesure réalisée sur Terre lorsqu'on veut l'interpréter en terme d'abondances au centre de l'étoile. La partie observationnelle de ce travail est focalisée sur l'amélioration de la précision de rapports isotopiques délicats à interpréter dans des enveloppes particulières: rapports d'éléments lourds de sources brillantes ou rapports des CNO dans des sources présentant des anomalies d'abondances. L'interprétation des observations a requis deux modélisations avancées dont l'une, faisant partie intégrante de cette thèse, porte sur l'émission de l'enveloppe, et l'autre, portant sur le processus "s", a fait l'objet d'une collaboration. Dans le domaine théorique, le code d'évolution stellaire de Grenoble a été optimisé pour les AGBS afin d'étudier l'influence de la modélisation physique et du traitement numérique du DUP sur la nucléosynthèse. Le cœur de la modélisation d'une étoile, l'équation d'état (EOS), a été réécrite et une grande partie du traitement numérique du code a été revue. La physique du mélange non standard a été incorporée et "l'arsenal" numérique nécessaire à la mise en œuvre de cette physique a fait l'objet d'une collaboration. Ce travail a permis la précision des caractéristiques d'enveloppes d'étoiles J (riches en 13C), la détermination de 35Cl / 37Cl dans IRC+10216 et la production d'outils de calcul performants pour les étoiles (même de faibles masses) et leurs enveloppes moléculaires. Mais il a surtout montré que l'incorporation de mélange non standard permet à la fois d'augmenter la profondeur du DUP et de produire une poche de 13C propice au processus "s". Ce fait, ajouté aux difficultés pour concilier les résultats d'observations des étoiles J avec les modèles, tend à réorienter le futur des modèles d'AGBS. Il faudrait disposer de modèle d'AGBS plus généraux, notamment pour les faibles masses, cohérents avec la physique et le numérique de la phase évolutive qui les précède, elle qui est naturellement modélisée avec du mélange non standard. En prime, les changements effectués dans le code et notamment l'élaboration d'une nouvelle EOS, ont permis de modéliser le flash de l'Helium et de produire des tracés d'étoiles pré séquence principale (PMS) jusqu'à 0.1 masse solaire concurrençant les codes les plus spécialisés.
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The nearby young [special character] Chamaeleontis cluster as a laboratory for star formation and evolutionLyo, A-Ran, Physical, Environmental & Mathematical Sciences, Australian Defence Force Academy, UNSW January 2004 (has links)
[Special characters cannot be displayed. Please see the pdf version of the Abstract for an accurate reproduction.] We studied the circumstellar discs, the initial mass function (IMF), mass distribution, binarity and the fundamental properties of the [special character] 9 Myr-old pre-main sequence (PMS) [special character] Chamaeleontis cluster. Using JHKL colour-colour and colour-excess diagrams, we found the circumstellar disc fraction to be [special character] 0.60 among the late-type members. Four stars with [special character] (K - L) > 0.4 were identified as experiencing ongoing accretion which was later confirmed by high-resolution spectroscopic study. Quantitative analysis of the H[special character] profiles found accretion in these four stars at rates comparable to that of two members of the similarly-aged TW Hydrae Association (TWA); rates 1 - 3 orders of magnitude lower than in younger classical T Tauri stars. Together these results suggest that, while the mass accretion rate decreases with age, PMS stars can retain their inner discs for [special character] 10 Myr. An optical photometric survey spanning 1.3 ?? 1.3 pc added two low-mass stars to the cluster inventory. Together with other recent surveys the population is likely to be significantly complete for primaries with masses M > 0.15M[special character]. The cluster now consists of 18 primaries and 9 confirmed and candidate secondaries, with [special character] 2-4 times higher multiplicity than seen in field dwarfs. The cluster IMF is consistent with that of rich young clusters and field stars. By extending the IMF to lower masses, we predict 20-29 low-mass stars and brown dwarfs may remain undiscovered. From study of the cluster???s spatial and mass distribution, we find the [special character] Cha cluster has significant mass segregation, with > 50 per cent of the stellar mass residing within the central 0.17 pc. Lastly we classified members of the cluster with low-resolution spectra, providing information about the fundamental properties of the PMS stars by comparison to standard dwarfs. Broadband VRI colours and pseudocontinuum indices derived for the cluster stars are indistinguishable from dwarfs at visual and red wavelengths. This suggests the temperature sequence for the PMS [special character] Cha cluster is similar to that of the dwarf sequence. Narrow-band spectral indices for the [special character] Cha cluster possibly indicate higher metallicity and strongly indicate lower surface gravity than the dwarf indices.
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[en] PROPOSAL OF A PERFORMANCE MEASUREMENT SYSTEM BASED ON THE BALANCED SCORECARD FOR THE CENTRAL TRANSPORTATION UNIT OF THE BRAZILIAN ARMY / [pt] PROPOSTA DE UM SISTEMA DE MEDIÇÃO DE DESEMPENHO BASEADO NO BALANCED SCORECARD PARA A UNIDADE CENTRAL DE TRANSPORTES DO EXÉRCITO BRASILEIROCAIO CESAR FERREIRA MODESTO MARQUES 09 October 2017 (has links)
[pt] Na atual conjuntura econômica, as organizações públicas devem prestar contas à sociedade através dos resultados e impactos que são capazes de gerar. O reconhecimento pela sociedade dos produtos gerados pelas organizações públicas se dá através da coerência nas decisões dos gestores com a eficiência, eficácia e efetividade na administração dos recursos disponíveis. Nesse sentido, é através da Gestão Estratégica que as organizações desenvolvem um processo contínuo e integrado de formulação, implantação, avaliação e correção da estratégia, capaz de conduzi-la à excelência no cumprimento da sua razão de existir (missão organizacional). O Balanced Scorecard é um Sistema de Medição de Desempenho que apoia o processo de implantação da estratégia, sendo o mais difundido e detalhado, o que garante melhor resultado na compreensão do desdobramento da estratégia em ações operacionais. Além dos motivos citados anteriormente, atendendo ao interesse do Exército Brasileiro de implantar o Sistema de Gestão Estratégica com o uso da metodologia BSC, esse trabalho buscou, através de um estudo de caso cumprindo as etapas de preparação da organização, formulação da estratégia e detalhamento, propor um Sistema de Medição de Desempenho baseado no Balanced Scorecard em apoio à Gestão Estratégica na Unidade Central de Transportes do Exército Brasileiro (Estabelecimento Central de Transportes), tendo como resultado a validação e utilização do sistema proposto, viabilizando a melhor gestão dos recursos disponíveis, adoção de uma mentalidade estratégica por parte dos militares envolvidos, além da aderência ao Programa de Excelência do Exército Brasileiro. / [en] In the current economic environment, public organizations must be accountable to society through the results and impacts that they are capable of generating. The recognition by society of the products generated by the public organizations is given through the coherence in the decisions of the managers with an efficiency, efficiency and effectiveness in the administration of the available resources. In this sense, it is through the Strategic Management that organizations develop a continuous and integrated process of formulation, implementation, evaluation and correction of the strategy, capable of leading it to excellence in fulfilling its reason for existing (organizational mission). The Balanced Scorecard is a Performance Measurement System that supports the process of implementing the strategy, being the most widespread and detailed, which guarantees a better result in understanding the strategy s deployment in operational actions. In addition to the reasons cited above, in view of the Brazilian Army s interest in implementing the Strategic Management System with the use of the BSC methodology, this work sought, through a case study fulfilling the steps of preparation of the organization, strategy formulation and detailing, to propose a Performance Measurement System based on the Balanced Scorecard in support of Strategic Management in the Central Transportation Unit (Estabelecimento Central de Transportes), resulting in a validity and use of the proposed system, making possible a better management of available resources, adoption of a strategic mentality on the military involved, in addition to adherence to the Program of Excellence of the Brazilian Army.
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Diagnóstico da síndrome pré-menstrual : comparação de dois instrumentos - registro diário da intensidade dos problemas (DRSP) e instrumento de rastreamento de sintomas pré-menstruais (PSST)Henz, Aline January 2016 (has links)
Introdução: O diagnóstico da Síndrome Pré-menstrual (SPM) é um desafio. O uso de questionários estruturados está bem estabelecido, e a ferramenta mais aceita é o DRSP, um questionário prospectivo auto preenchido por ao menos dois meses. O PSST é um questionário retrospectivo de autoaplicação, preenchido em um único momento. Objetivo: comparar estes dois instrumentos (PSST e DRSP) para o diagnóstico da SPM. Método: Um estudo transversal com 127 mulheres entre 20 a 45 anos com queixas de SPM. As mulheres foram avaliadas quanto ao peso, altura, Índice de Massa Corporal (IMC). Após exclusão de casos de depressão através do Prime-MD, as pacientes completaram o PSST e foram orientadas a preencherem o DRSP durante dois meses. A concordância entre os dois questionários foi avaliado pelo cálculo de Kappa (k) e valores do coeficiente PABAK. Resultados: Do total de mulheres que atenderam ao chamado, 282 (74%) preencheram os critérios de elegibilidade e responderam o PSST. Entre estas 282 mulheres, somente 127 (45%) completaram o questionário diário (DRSP) por dois ciclos. O percentual das mulheres com diagnóstico de SPM através do DRSP foi de 74,8%, e pelo PSST foi 41,7%. O percentual das mulheres com diagnóstico de TDPM pelo DRSP foi de 3,9%, e pelo PSST foi de 34,6%. Assim, verificou-se uma maior prevalência de SPM com o DRSP do que com o PSST. De outra parte a TDPM foi mais dignosticada pelo PSST do que com o DRSP. O número de pacientes consideradas “normais” foi semelhante com os dois instrumentos. Na avaliação entre os dois instrumentos verificou-se não haver nenhuma concordância (Kappa = 0,12) nos resultados do diagnóstico de SPM e TDPM (Coeficiente Pabak resultou = 0,39). Para a trigem de SPM/TDPM o PSST tem uma sensibilidade de 79% e especificidade de 33,3%. Conclusão: O PSST deve ser considerado como uma ferramenta de triagem diagnóstica. Conclui-se que os casos SPM/TDPM do PSST devem ser sempre melhor avaliados pelo DRSP. / Background: The diagnosis of Premenstrual Syndrome (PMS) is a challenge. The use of structured questionnaires is well established and the most accepted is the DRSP, a prospectively self-administered questionnaire that needs two months at least to be completed. The PSST is a retrospective self-scale questionnaire, filled at a single time. Aim: To compare these two instruments (PSST and DRSP) to diagnosis PMS. Methods: A cross-sectional study with 127 women between 20 and 45 years with PMS complaints. The women were evaluated about weight, high, Body Mass Index (BMI). After the exclusion of depression by the Prime-MD Questionnaire, the PSST was completed and the women were oriented to complete the DRSP for two months. The agreement between the two questionnaires was assessed by calculating the Kappa (k) and PABAK values. Results: 282 (74% of all the women) women met eligibility criteria and answered the PSST. Only 127 (45% of the 282 women) completed the daily questionnaire (DRSP) for two cycles. The percentual of women with PMS diagnosis by the DRSP was 74.8%, and by PSST was 41.7%. The percentual of women with PMDD diagnosis by the DRSP was 3.9%, and by the PSST was 34.6%. The number of patients considered “normal” (with the symptoms above the necessary for the diagnostic the PMS) was similar with both questionnaires. We found no agreement between the two instruments (Kappa = 0.12) in the diagnosis of PMS and PMDD (Pabak coefficient keep this result = 0.39). For screening PMS/PMDD the PSST has a sensitivity of 79% and a specificity 33.3%. Conclusion: The PSST should be considered as diagnostic screening tool. We concluded that positive PMD/PMDD cases of PSST should be ever better evaluated by DRSP.
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An evaluation of a performance management system in a freight rail organisationMbonambi, S'thembiso Samuel 03 1900 (has links)
The purpose of this study was to evaluate the effectiveness of the existing performance management system (PMS) in enhancing performance at this freight rail organisation (FRO). The focus of this study was to establish whether the performance management processes are effective in enhancing the individual performance level in this FRO. The performance management processes referred to in this study include conceptualising and exploring; performance management and its processes, the balanced scorecard (BSC) as a tool of performance management and explaining the relationship between performance management and a reward system within the FRO.
A qualitative research design was used for this study to answer the research question. The research design consisted of a case study where thirty semi structured interviews were conducted with the first line managers, junior managers, middle managers and senior managers at this FRO. The interviews were transcribed, and research data was analysed using a content analysis method.
This study yielded a number of benefits in terms of the research findings, conclusions and recommendations about the effectiveness of performance management processes, the BS and the relationship between individual performance and reward. As a result, the study will not only benefit management in dealing with a strategy and drive individual performance, but will also assist all levels of employees within the FRO and other organisations in understanding the day-to-day operational activities of performance management. It will also help human capital professionals, industrial psychologists at the FRO and other organisations in knowing and understanding the best practices to adopt, in managing their individual performance levels. / Industrial and Organisational Psychology / M. Com. (Industrial and Organisational Psychology)
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Síndrome pré-menstrual : relação entre a intensidade dos sintomas e a reserva ovarianaOderich, Carolina Leão January 2017 (has links)
Introdução. A Síndrome Pré-menstrual (SPM) é caracterizada por sintomas de estresse somáticos e comportamentais que se desenrolam logo após a ovulação, atingindo um pico máximo próximo à data da menstruação e desaparecendo em média em até quatro dias após o início do sangramento. A presença da formação do corpo lúteo seria necessária para a presença dos sintomas, contudo essa dinâmica dos hormônios da fase lútea associados à SPM é pouco conhecida. O hormônio antimülleriano (HAM) é um dos melhores marcadores de declínio da capacidade reprodutiva das mulheres. Até o momento o mesmo não foi correlacionado a sintomas da SPM. A percepção de piora dos sintomas da SPM na perimenopausa é sugerida, existindo a possibilidade de que com a menor função ovariana (redução do HAM) exista uma exacerbação da SPM durante essa fase da vida reprodutiva da mulher. Objetivo: avaliar o padrão de SPM em mulheres com idade superior a 35 anos e correlacionar seus sintomas com a redução de HAM. Métodos: Estudo observacional, transversal, com uma amostra de conveniência composta por mulheres recrutadas através da mídia local. O questionário Registro Diário da Intensidade de Problemas (DRSP) de 2 meses foi utilizado para o diagnóstico de SPM. As participantes (N = 101) foram avaliadas em seus perfis antropométricos (peso, altura, índice de massa corporal) e social (paridade, nível educacional, uso de contracepção oral). Depois de completar o questionário DRSP por 2 meses, as mulheres retornaram no período prémenstrual para a coleta do sangue. Entre as participantes que utilizaram contracepção hormonal, foi solicitado um período de wash out de um mês para a coleta de sangue e dosagem de HAM no soro. O HAM foi analisado usando um kit comercial ELISA, de acordo com as instruções do fabricante. A análise estatística foi realizada na versão SPSS 18.0. O nível de significância adotado para todas as análises foi estabelecido em 5%. Resultados: A análise de HAM mostrou uma redução significativa após a idade de 35 anos, e não foi relacionada à severidade dos sintomas de SPM. Os sintomas físicos na fase lútea, mas não os emocionais, foram maiores em mulheres com mais de 35 anos de idade. A análise de Spearman mostrou uma correlação positiva entre um grupo de ≥35 anos e uma correlação negativa entre o uso de contracepção oral com piora dos sintomas físicos da SPM. Conclusão: este estudo mostrou que não houve piora dos sintomas emocionais entre as mulheres com SPM após os 35 anos de idade, apenas piora dos sintomas físicos, que necessitam uma investigação mais aprofundada. Não há relação entre os sintomas físicos e emocionais com níveis de HAM nas mulheres com SPM. / Background. Premenstrual Syndrome (PMS) is characterized by somatic and behavioral stress symptoms that take place soon after ovulation, reaching a peak near the time of menstruation and disappears on average within 4 days after the start of the bleeding. The presence of the corpus luteum formation would be needed for the presence of symptoms, however, these dynamics luteal phase of hormones associated with PMS is not well known. The anti-müllerian hormone (AMH) is one of the best markers of decline in women's reproductive capacity, and AMH has not been correlated with PMS symptoms. The perception of worsening of PMS symptoms in perimenopause is suggested, with the possibility that with less ovarian reserve (reduction of AMH) there is an exacerbation of PMS during this phase of the woman's reproductive life. Objective: To evaluate the pattern of PMS in women aged over 35 years, and correlate its symptoms to the reduction of AMH. Methods: It was an observational, cross-sectional study with a convenience sample composed of women recruited through local media. The 2-months DRSP questionnaire was used for PMS diagnosis. The participants (N=101) were evaluated in their anthropometric (weight, height, body mass index) and social (parity, educational level, use of oral contraception) profiles. After completing the DRSP questionnaire for 2 months, women returned in the pre-menstrual period for serum collection. Among participants using hormonal contraception, a one-month washout period was requested for serum collection and AMH dosage. AMH was analyzed using an ELISA commercial kit, according the manufacturer’s instructions. Statistical analysis was carried out in SPSS version 18.0. Significance level adopted for all analyzes was set at 5%. Results: AMH analysis showed a significant reduction after the age of 35 years, and it was not related to PMS symptoms severity. Physical symptoms in luteal stage were greater in women aged over 35 years, emotional symptoms were equal in both ages. Spearman’s analysis showed a positive correlation between ≥ 35years group and a negative correlation between the use of oral contraception with PMS physical symptoms worsening. Conclusion: this study showed that there is no worsening of emotional symptoms among women with PMS after 35 years of age, with a greater physical complaint, that needs further investigation. There is no relation between the physical and emotional symptoms with AMH levels in PMS women.
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