Thesis (MSc)--Stellenbosch University, 2014. / ENGLISH ABSTRACT: Pregnant women living in South African peri-urban settlements face many challenges for their health and the health of their infants. Current health care services face many constraints and are not able to meet all the needs of pregnant mothers. Home-visiting programmes implemented by community health workers can alleviate these constraints. The current RCT assessed the effectiveness of the Philani Plus Intervention Program that addressed HIV, alcohol, maternal and child nutrition and mental health. The effectiveness of the intervention was assessed by measuring infant social withdrawal behaviour using the modified Alarm Distress Baby Scale (m- ADBB). A total of 681 cases were randomised into control (N=330) and intervention groups (N=351) and assessed using the m-ADBB. A cut-off score of two and above was used to determined significant social withdrawal behaviour. Data was analysed using descriptive statistics and cross-tabulation initially, followed by analysis of variance and multilevel modelling. Results indicated a prevalence of 46.7% of social withdrawal behaviour; however, no significant differences between groups were found. The current prevalence was substantially higher in comparison to the only other published study using the m-ADBB. Furthermore, the prevalence rate was also significantly higher compared to the majority of other studies using the original Alarm distress Baby Scale (ADBB). The high prevalence of social withdrawal behaviour found in this study indicates an increased risk for suboptimal infant development. Further research regarding social withdrawal behaviour and the casual mechanisms associated with the development of such behaviour is needed. Furthermore, validation of the m-ADBB in different settings is needed. / AFRIKAANSE OPSOMMING: Swanger vroue wat in Suid-Afrikaanse buitestedelike nedersettings woon staar baie uitdagings in die gesig met betrekking tot hul gesondheid en die gesondheid van hul babas. Huidige gesondheidsdienste is baie beperk en is nie in staat om in al die behoeftes van swanger moeders te voorsien nie. Huis-besoek programme wat deur gemeenskaplike gesondheidswerkers geïmplementeer word, kan hierdie beperkings verlig. Die huidige RCT het die effektiwiteit van die Philani Plus Intervensie Program wat MIV, alkohol, voeding en geestelike gesondheid aanspreek, geassesseer. Die effektiwiteit van die intervensie is geassesseer deur sosiale onttrekkingsgedrag met behulp van die gewysigde Alarm Nood Baba Skaal (m-ADBB) te meet. ‘n Totaal van 681 gevalle is lukraak in kontrole (N = 330) en intervensie groepe (N = 351) verdeel en geëvalueer volgens die m-ADBB. 'n Afsnypunt van twee en hoër is gebruik om beduidende sosiale onttrekkingsgedrag te bepaal. Data is aanvanklik ontleed met behulp van beskrywende statistiek en kruis-tabulering, gevolg deur analise van variansie en multi-modelle. Resultate toon 'n 46,7%-voorkoms van sosiale onttrekkingsgedrag, maar het egter geen beduidende verskille tussen groepe getoon nie. Die huidige voorkoms was aansienlik hoër in vergelyking met die enigste ander gepubliseerde studie wat gebruik gemaak het van die m- ADBB. Verder was die voorkomssyfer ook aansienlik hoër in vergelyking met die meerderheid van die ander studies wat gebruik gemaak het van die oorspronklike Alarm Nood Baba Skaal (ADBB). Die hoë voorkoms van sosiale onttrekkingsgedrag dui op 'n verhoogde risiko vir suboptimale baba ontwikkeling. Verdere navorsing oor sosiale onttrekkingsgedrag en die meganismes wat verband hou met die ontwikkeling van sulke gedrag, is nodig. Verder word die bekragtiging van die m-ADBB in verskillende instellings benodig.

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In step with the development of society, new social phenomena develop where ”acute social withdrawl” is one of them. Acute social withdrawl is a phenomenon that is about individuals ending up in a social isolation where they withdraw from different relationships and contexts, such as school. Problematic school absenteeism is something that student health works withdaily so students don´t become acute social withdrawn. Based on previous research, we find that early coordinated interventions are significant for the preventive work towards individuals who are at risk for becoming acute social withdrawn. However, we see a knowledge gap in how this type of work should be performed. Through a qualitativ studie in the form of semistructured interviews, we interviewed six people who work actively in a student health team to gain deeper understanding of their work with early interventions. The theories we used to analyze the empirical meterial are Collaboration, Systems theory and Empowerment. Based on our study, we could see several conclusions. For example, we saw that the different interviewees had different functioning processes to draw attention to the students needs, and that collaboration with external organisations worked differently in different municipalities. This is due to the availability, resorurces and willinggness. That it´s not only being meetings and meetings without any results. Based on this, we can se that student health´s work with early coordinated interventions is limited and instead we saw that the interviewees themselves, in their professional role had to find their own 3(64)strategies. In Conclusion, we can see that a group perspective is lacking inte work, as there is a lot of individual focus.

Ce travail de mémoire porte sur le processus d’insertion sociale et économique des personnes vivant des problèmes de santé mentale. Le travail est devenu un important véhicule d’intégration sociale. En effet, on prétend que la pratique d’un métier serait pour les personnes souffrant de problèmes de santé un outil de rétablissement et de mieux-être, car elle permet de réduire les symptômes et l’incidence des hospitalisations. Le travail permet, également, d’augmenter les interactions sociales et de contribuer activement à la société. Il existe, toutefois, d’autres véhicules d’intégration qui semblent, sous certains angles, apporter les mêmes avantages. Les activités bénévoles améliorent la qualité de vie, favorisent les interactions sociales et donnent, à l’individu, l’occasion de contribuer à sa communauté. Par ailleurs, le retrait social peut être un moyen de s’éloigner des pressions sociales et de s’accorder une pause bénéfique. On soutient que les personnes ayant un problème de santé mentale qui ont une lecture positive de leur situation de marginalité tendent à être moins hospitalisées. S’appuyant sur une démarche qualitative, ce travail de recherche a tenté de cerner les perspectives, les questionnements et les perceptions des personnes ayant un trouble mental à l’égard d’un processus d’intégration socioprofessionnelle, de participation sociale et de retrait social. Des entrevues semi-dirigées ont été menées auprès de onze personnes, et grâce à ces entretiens, un portrait au regard de leurs parcours social et professionnel a pu être brossé. Les entretiens ont permis d’explorer l’impact des problèmes de santé mentale sur leur réalité et sur leur identité, leurs représentations du marché de l’emploi et les motifs qui justifient le choix de s’engager ou de renoncer à un processus d’intégration socioprofessionnelle. Les résultats de cette recherche ont permis d'identifier cinq facteurs qui peuvent influencer la décision des personnes qui sont le rapport à l'environnement social, l'identité, le rapport aux institutions de l'État, les discours de légitimation et les perspectives d'avenir. Les résultats démontrent que l'on ne peut isoler les notions de vulnérabilité, d'autonomie, de bien-être ou de stabilité dans une phase spécifique. La vulnérabilité, l'autonomie, le bien-être et la stabilité sont des états que l’on peut vivre en situation de retrait social, de participation sociale et d’intégration socioprofessionnelle. Selon les circonstances et l’état émotif, ils peuvent être des modes adaptés ou inadaptés. / This theisis explores the social and economic integration of people with mental health problems in regard to paid work. Work has become an important vehicle for social integration. Indeed, it is argued that having an occupation could be a tool to recovery and wellness in that it can reduce symptoms and prevent hospitalisation. Work also allows for increased social interactions and active participation in society. There are however, other vehicles for social integration that have the possibility of providing the same advantages as work. Volunteer activities improve the quality of life, promote social interaction and provide opportunities to contribute to community life. Moreover, social withdrawal can be viewed as a way to attain a sense of distance from social pressures and thus provide a beneficial break. It is argued that persons with mental health problems who have a positive perception of their marginal situation have a lower tendency for hospitalisation. Based on a qualitative approach, this research has attempted to identify the reasons why people with a mental disorder engage in a process of socio-professional integration, social participation and social withdrawal. Semi-structured interviews were conducted with 11 people, and through these interviews, a portrait of their social and professional process has been presented. The interviews explored the impact of mental health problems on their reality and their identity, what the labour market represents, and the reasons that justify the decision to commit or to abandon a process of socio-professional integration. This research has demonstrated that there are five factors that can influence people’s decisions: the relationship to the social environment, identity, the relationship to state institutions, legitimizing discourses and future perspectives. The results show that we can isolate the notions of vulnerability, autonomy, well-being or stability in a specific phase. Vulnerability, autonomy, well-being and stability are states that can be lived in a situation of social withdrawal, social participation and professional integration. Depending on the circumstances and the emotional state of the person, they may be considered adaptive or inadequate modes of adaptation.

Ce travail concerne le comportement de retrait relationnel du jeune enfant, sa mesure et sa validité prédictive sur la qualité du développement précoce dans ses différentes dimensions. Il représente la première synthèse de l'histoire du concept de retrait relationnel du jeune enfant, de ses liens avec les modèles animaux, avec le modèle paradigmatique du "Still Face" et de la réparation, de la dys-synchronie comme facteur majeur de la psychopathologie précoce. Le comportement de retrait relationnel prend ses racines dans la physiologie, comme mode privilégié de régulation par le bébé de l'interaction, dans une échelle micro interactive. D'une façon plus clinique et sur une échelle temporelle plus longue, il apparaît comme un mode de défense majeur face à la violation des attentes du bébé dans l'interaction. On l'observe donc de façon privilégiée dans la dépression maternelle post natale mais aussi dans toutes les circonstances psychopathologiques qui affectent les capacités parentales (par exemple et de façon très nette dans les situations de conflit et violences conjugales). Le retrait relationnel peut également être lié à des difficultés de traitement de l'information sensorielle par le bébé, à des difficultés de communication sociale, à une douleur intense prolongée, et dans la prématurité ou dans certains syndromes génétiques à une association de ces facteurs liés à l'enfant. Ce travail retrace les débuts de la construction d'un outil de mesure du retrait relationnel précoce, dans la mesure où cet outil n'existait pas en tant que tel, alors que le retrait relationnel apparaît comme un signal d'alarme important, témoignant de la difficulté du bébé de jouer le jeu relationnel à hauteur de ses capacités développementales, que ce soit pour des causes liées à lui-même, à la relation avec ses caregivers, ou aux deux. Ce travail s'ouvre par une histoire de la psychiatrie du bébé et de l'avènement de la psychopathologie développementale, car on note l'importance du symptôme retrait dans cette histoire, qu'il s'agisse de l'autisme (Kanner) ou de la dépression ou de la carence précoces (Spitz), puis un historique de concept de retrait relationnel précoce : contexte clinique modèles animaux, biologie, la Construction et validation de l'échelle Alarme Détresse bébé (ADBB à 8 items) puis celle de la m-ADBB à 5 items, puis par la Psychopathologie du retrait relationnel durable, et Les développements et les applications de l'échelle ADBB : m-ADBB, effets à terme du retrait, études longitudinales, la prématurité comme analyseur du développement, dépistage précoce de l'autisme et enfin les projets en cours et trois projets actuels, autour du dépistage de l'autisme, autour de l'étude des différentes analyses factorielles et de la validation de la m-ADBB, et autour des pistes génétiques et épigénétiques du comportement de retrait. Il présente les résultats des études contrôlées et publiées avec l'ADBB, en particulier celles liées à la cohorte française d'étude des facteurs de risque et de résilience du développement précoce (étude périnatale EDEN). Le comportement clinique de retrait relationnel apparaît comme le résultat d'une interaction gène environnement, basée sur la susceptibilité génétique au comportement de retrait. Celle-ci apparaît liée au système allélique 5-HTTPR. Sur le plan cognitif, la question se pose du retrait comme pari, comme choix dans une situation d'incertitude. Les études de suivi des enfants en retrait montrent l'impact sur diverses dimensions du développement, langage, intersubjectivité, régulation émotionnelle, avec la question d'une période sensible. Ceci souligne l'importance du dépistage de ce comportement en vue d'une intervention précoce adaptée à sa cause. / This work deals with social withdrawal behavior in infants, its measure and its conceptual validity, its predictive value on early development within its several dimensions. This is the first synthesis on the history of the concept of withdrawal in infant, of its links with animal models, with the still face experimental paradigm, as well as with the repair process and with interactional dys- syssynchrony as a major process in early psychopathology. Social withdrawal behavior has its roots in physiology, as privileged way used by the infant to regulate the input within the parent infant interaction, within a micro temporal scale. On a longer temporal and more clinical scale, withdrawal behavior appears as a major defense maneuver when the baby is faced with major violations of his her expectations within the relationship. It is therefore observed in a privileged way in maternal post-natal depression, but also in all circumstances which hamper parental capacities, as conjugal violence and conflict may do for instance. Social withdrawal behavior may be as well linked with difficulties in processing sensorial input in the child, or difficulties in social communication and synchrony, or be due to an intense and sustained pain, or be linked with some genetic disorder or with some association of these factors. This work retraces the construction of a scale to asses social withdrawal behavior in infants, since no such tool existed at the time, although social withdrawal behavior appears to be an important alarm signal, showing the inability of the child to play the relational game as his her developmental level allow him or her to do, be it for causes related to himself or herself, for relational causes of because of both. This work opens on a history of the development of child psychiatry and of the coming of ages of infant development. Social withdrawal behavior took a large place at the onset of this history, with the description of autism by Kanner and anaclitic depression by Spitz. Then a history of the concept of social relational withdrawal, and of the construction of the alarm distress scale (8 item) the of the short version (5 item m-ADBB), then the studies on long term effects of social withdrawal on development. We then review the application of the scale on early diagnosis of autism, on the several factor analysis with several samples, and of the several epigenetic and genetic pathways of the social withdrawal behavior. This work reviews the results of several controlled studies with the ADBB, particularly those from the perinatal French EDEN cohort. Social withdrawal behavior appears as the result of a gene interaction, based on the genetic c susceptibility for social withdrawal behavior, possibly liked with the 5-HTPPR allele system. On a cognitive level, the issue is raised of social withdrawal behavior as a choice of a risk taking position in an uncertain situation. Follow up studies show the impact of the social withdrawal behavior on several dimensions of early development, i.e. language, early development of intersubjectivity or emotional regulation.

The Minnesota Multiphasic Personality Inventory-2 (MMPI-2) is a popular measure of psychosocial functioning and psychopathology in the assessment of individuals in a variety of settings. However, the method of construction employed with the MMPI more than 60 years ago with psychiatric patients challenges the applicability of the scales for determining the psychosocial functioning of individuals from different settings. The restandardisation conducted in 1987 made no effort to eradicate the item overlap that was a result of the criterion keying method with contrasted groups. Although restandardized and updated with more contemporary language and content, the original psychiatric constructs were retained in order to maintain continuity with its predecessor. The aims of this investigation were to develop a new structure for the MMPI-2 constructed at the item-level, empirically derived and which specifically represents the dimensions that are relevant and appropriate in evaluating the psychosocial functioning of personal injury claimants. This task included comparisons with a comparable scale-level analysis and developing optimal scoring strategies where items in components and facets are allocated weightings based upon their strength of association. Study 1 was conducted using a sample of 2989 personal injury claimants assessed in Australia and the United States of America. The final sample of 3230, included 241 normal individuals, was utilized to develop a scale-level structure from 79 standard MMPI-2 scales and subscales. A nine-component solution consisting of General Maladjustment /Emotional Distress, Asocial Beliefs, Social Vulnerability, Somatic Complaints, Psychological Disturbance, Impulsive Expression, Antisocial Practices, Stereotypic Fears and Family Difficulties was derived using principal component analysis. However, intercorrelation between components in the structure signaled the need to develop a structure that would eradicate problems that were perpetuated by item overlap. The second study was conducted with a set of best practice procedures with the same clinical sample of 2989 personal injury claimants as Study 1. Forty-one components were derived through principal component analysis. Through the application of a set of criteria, a 35-component solution was retained. The pattern coefficients from the allocation of items to components determined the weightings to be applied to each item. Further analysis of the 35 components derived a substructure of 37 facets. The 35 components included only 442 of the 567 items, with the reliability coefficients of the first 25 components that ranged between .5 and .97, and the remaining 10 components that ranged from .29 to .49. The latter unreliable components were not included in the final Structural Summary, leaving 25 components (400 items) and their 33 facets for interpretation. Hence, in demonstrating the utility of the newly-derived structure, only 25 components and their 33 facets were interpreted. The 25 components were grouped conceptually into six domains. In the emotional domain were Psychological Distress (PsyDist), Anger, Fears, Psychotic Symptoms (PsyS), Paranoia (Par), Irritability (Irrit), Elation (Elat), Fear of the Dark (FD), and Financial Worry (FinWo). Somatic Complaints (SomC), Sexual Concerns (SexCon), and Gastrointestinal Problems (GasP) made up the measures in the physiological domain. In the behavioural domain were Cognitive Difficulties (CogDiff), Stimulus-Seeking (StimuS), Discipline (Dis), and Delinquency (Del) whilst the interpersonal domain was formed by Social Withdrawal (SoW), Negative Interpersonal Attitude (NIA), Timidity (Tim), Lie, Dissatisfaction with Self (DWS) and Family Relationship Difficulties (FReD). Alcoholism (Alco) was the only measure in the substance abuse domain, and the gender domain was comprised of Masculinity (Mas) and Femininity (Fem). The third study established preliminary normative means and standard deviations using a small opportunistic Australian university student sample (N = 219). No substantial gender differences were found but gender norms were maintained to facilitate comparisons with the traditional MMPI-2 approach. Comparisons of frequency of 'true' item response between the Australian university student sample and the U.S. restandardisation sample found relatively little differences and permitted evaluation of between sample differences on components and facets. The utility of the structure was demonstrated with the illustration of two clinical case examples, and a comparison was made with the standard MMPI-2 scales and subscales. The Structural Summary for the MMPI-2 demonstrated discriminative measures of psychosocial functioning that were a result of no item overlap, and the ability to attend to the different levels of intensity of self-report items because of differential weightings.