No description available.

Résumé : Le contrôle de la chimie de l'eau dans un réacteur nucléaire refroidi à l'eau nécessite une compréhension détaillée des effets de la radiolysede l'eau afin de limiter la corrosion et la dégradation des matériaux par oxydation générée par les produits de cette radiolyse. Toutefois, la mesure directe de la chimie dans le cœur des réacteurs est extrêmement difficile, sinon impossible, en raison des conditions extrêmes de haute température et haute pression, et les champs d’irradiation mixtes neutrons/γ, qui ne sont pas compatibles avec l'instrumentation chimique normale. Pour ces raisons,des modèles théoriques et des simulations sur ordinateur sont essentielles pour la prédiction de la chimie sous rayonnement de l'eau de refroidissement dans le cœur et son impact sur les matériaux. Dans ce travail, des simulations Monte Carlo ont été utilisées pour calculer les rendements des principales espèces (e[indice supérieur -][indice inférieur aq], H[indice supérieur •], H[indice inférieur 2], [indice supérieur •]OH et H[indice inférieur 2]O[indice inférieur 2]) formées lors de la radiolyse de l’eau liquide neutre par des neutrons mono-énergétiques de 2 MeV à des températures entre 25 et 350 °C. Le choix des neutrons de 2 MeV comme énergie d'intérêt est représentatif du flux de neutrons rapides dans un réacteur. Pour l'eau légère, la contribution la plus significative à la radiolyse vient des quatre premières collisions des neutrons qui produisent, dans la majorité des cas, des protons avec des énergies de recul de ~1.264, 0.465, 0.171 et 0.063 MeV et des transferts d’énergie linéique (TEL) moyens respectivement de ~22, 43, 69et 76 keV/[micro]m. Par ailleurs, nous avons négligé les effets des radiations dus aux ions de recul de l’oxygène. Les rendements moyens finaux peuvent alors être estimés comme étant la somme des rendements résultant de l’action de ces protons après pondérations en fonction de l’énergie déposée. Les rendements ont été calculés à 10[indice supérieur -7], 10[indice supérieur -6] et 10[indice supérieur -5] s. Les valeurs obtenues sont en accord avec les données expérimentales disponibles. En comparant nos résultats avec les données obtenues pour les rayonnements à faible TEL (rayons γ de [indice supérieur 60]Co ou électrons rapides), nos rendements calculés pour les neutrons rapides ont montré une dépendance en température essentiellement similaire, mais avec des valeurs plus faibles pour les rendements en radicaux libres et des valeurs plus élevées pour les rendements moléculaires. Nous avons également utilisé les simulations Monte Carlo pour étudier l'existence de la chute rapide de la constante de vitesse de réaction de l'électron hydraté (e[indice supérieur -][indice inférieur aq]) sur lui-même – l’une des principales sources de formation de H[indice inférieur 2] – au-dessus de 150 °C. Cette dépendance en température a été observée expérimentalement en milieu alcalin par divers auteurs, mais jamais en milieu neutre. Lorsque cette baisse de la constante de vitesse d’auto-réaction de e[indice supérieur -][indice inférieur aq] est incluse dans nos codes de simulation, tant pour des rayonnements de bas TEL (grappes isolés) que de haut TEL (trajectoires cylindriques), g(H[indice inférieur 2]) montre une discontinuité marquée à la baisse à ~150°C, ce qui n'est pas observée expérimentalement. Les conséquences de la présence de cette discontinuité dans le rendement en H[indice inférieur 2] pour les rayonnements à bas et haut TEL sont discutées. Enfin, nous avons tenté d’expliquer l'augmentation – considérée comme anormale – du rendement en H[indice inférieur 2] en fonction de la température au-dessus de 200 °C par l’intervention de la réaction des atomes H[indice supérieur •] avec l'eau, préalablement proposée par Swiatła-Wojcik et Buxton en 2005. La constante de vitesse de cette réaction est toujours controversée. // Abstract : Controlling the water chemistry in a water-cooled nuclear power reactor requires understanding and mitigating the effects of water radiolysis to limit the corrosion and degradation of materials by oxidizing radiolysis products. However, direct measurement of the chemistry in reactor cores is extremely difficult due to the extreme conditions of high temperature, pressure, and mixed neutron/γ-radiation fields, which are not compatible with normal chemical instrumentation. For these reasons, theoretical models and computer simulations are essential for predicting the detailed radiation chemistry of the cooling water in the core and the impact on materials. Monte Carlo simulations were used to calculate the yields for the primary species (e[superscript -][subscript aq], H[superscript •], H[subscript 2], [superscript •]OH, and H[subscript 2]O[subscript 2]) formed from the radiolysis of neutral liquid water by mono-energetic 2-MeV neutrons and the mechanisms involved at temperatures between 25 and 350 °C. In this work, we chose 2-MeV neutron as our energy of interest since it is known as representative of a fast neutron flux in a nuclear reactor. For light water, for that chosen energy, the most significant contribution to the radiolysis comes from the first four neutron collisions that generate mostly ejected protons with energies of ~1.264, 0.465, 0.171, and 0.063 MeV, which had, at 25 °C, mean linear energy transfers (LETs) of ~22, 43, 69, and 76 keV/[micro]m, respectively. In this work, we simply neglected the radiation effects due to oxygen ion recoils. The average final fast neutron yields could be estimated as the sum of the yields for these protons after allowance was made for the appropriate weightings (by using the Eq (2) in Chapter 4) according to their deposited energy. Yields were calculated at 10[superscript -7], 10[superscript -6] and 10[superscript -5] s. Our computed yield agreed reasonably well with the available experimental data. By comparing our results with data obtained for low-LET radiation ([superscript 60]Co γ-rays or fast electrons), our computed yields for fast neutron radiation showed essentially similar temperature dependences over the range of temperature studied, but with lower values for yields of free radicals and higher values for molecular yields. In this work, we also used our Monte Carlo simulation to investigate the existence of drop of hydrated electron (e[superscript -][subscript aq]) self-reaction rate constant at 150 °C. One of the main sources of H[subscript 2] formation is the self-reaction of hydrated electrons. The temperature dependence of the rate constant of this reaction (k[subscript 1]), measured under alkaline conditions, reveals that the rate constant drops abruptly above ~150 °C. However, when this drop in the e[superscript -][subscript aq] self-reaction rate constant is included in our code for low (isolated spurs) and high (cylindrical tracks) linear energy transfer (LET), g(H[subscript 2]) shows a marked downward discontinuity at ~150 °C which is not observed experimentally. The consequences of the presence of this discontinuity in H[subscript 2] yield for both low and high LET radiation are discussed. Another reaction that might explain the anomalous increasing of H[subscript 2] yield with temperature is the reaction of H[superscript •] atoms with water previously proposed by Swiatla-Wojcik and Buxton (2005) whose rate constant is still in controversial.

The following thesis project has been done in direct collaboration with Autokaross i Floby AB Rescue Vehicle Department, in Sweden.  The report contains the design development of a protective cover against weather conditions for the extendable ladder in a fire vehicle.   The aim of the report has been to develop a functional and low cost solution cover for the FEL on a fire truck, which is allocated on the roof, with the express intention of providing adequate access and protection against weather conditions in Nordic countries, so as to prevent premature deterioration of the FEL unit. The company has set the technical and conceptual boundaries, with the help of the two previous concepts currently used, the BMC and the ACP.   The initial requirements laid out by the company were expressed through a number of specific demands which can be categorized in two main points:   Cost: Designing a solution keeping in mind cost limits, assembly cost and time, and space optimization. This was done by taking into account the two existing solutions, particularly the BMC, which represents the lowest, cost wise and function wise. Therefore it was used as the basis on which to apply improvements, rather than trying to lower the high cost on the overqualified function of the ACP.   Function: Providing the adequate protection and access to the FEL. In this case, the problem was solved by establishing the correct degree of protection relevant to the Nordic weather conditions and FEL needs, and regarding the access, this was assured by fully automating the opening/closing process with the existing extraction operating system of the FEL.     The result of this report is a concept solution which meets the company’s demands, obtained by creative detailing, together with an analysis regarding possible considerations that could improve the creative detailing result in this report in the form of future work.     The report documents the process that has taken place in exploration, concept generation, concept evaluation, concept selection, and detailed CAD development. Each section shows the requirements and adjustments taken to fulfil the company’s needs.

Résumé : Les ions hydronium (H3O + ) sont formés, à temps courts, dans les grappes ou le long des trajectoires de la radiolyse de l'eau par des rayonnements ionisants à faible transfert d’énergie linéaire (TEL) ou à TEL élevé. Cette formation in situ de H3O + rend la région des grappes/trajectoires du rayonnement temporairement plus acide que le milieu environnant. Bien que des preuves expérimentales de l’acidité d’une grappe aient déjà été signalées, il n'y a que des informations fragmentaires quant à son ampleur et sa dépendance en temps. Dans ce travail, nous déterminons les concentrations en H3O + et les valeurs de pH correspondantes en fonction du temps à partir des rendements de H3O + calculés à l’aide de simulations Monte Carlo de la chimie intervenant dans les trajectoires. Quatre ions incidents de différents TEL ont été sélectionnés et deux modèles de grappe/trajectoire ont été utilisés : 1) un modèle de grappe isolée "sphérique" (faible TEL) et 2) un modèle de trajectoire "cylindrique" (TEL élevé). Dans tous les cas étudiés, un effet de pH acide brusque transitoire, que nous appelons un effet de "pic acide", est observé immédiatement après l’irradiation. Cet effet ne semble pas avoir été exploré dans l'eau ou un milieu cellulaire soumis à un rayonnement ionisant, en particulier à haut TEL. À cet égard, ce travail soulève des questions sur les implications possibles de cet effet en radiobiologie, dont certaines sont évoquées brièvement. Nos calculs ont ensuite été étendus à l’étude de l'influence de la température, de 25 à 350 °C, sur la formation in situ d’ions H3O + et l’effet de pic acide qui intervient à temps courts lors de la radiolyse de l’eau à faible TEL. Les résultats montrent une augmentation marquée de la réponse de pic acide à hautes températures. Comme de nombreux processus intervenant dans le cœur d’un réacteur nucléaire refroidi à l'eau dépendent de façon critique du pH, la question ici est de savoir si ces fortes variations d’acidité, même si elles sont hautement localisées et transitoires, contribuent à la corrosion et l’endommagement des matériaux. / Abstract : Hydronium ions (H3O+) are formed within spurs or tracks of the low or high linear energy transfer (LET) radiolysis of pure, deaerated water at early times. The in situ radiolytic formation of H3O+ renders the spur and track regions temporarily more acid than the surrounding medium. Although experimental evidence for an acidic spur has already been reported, there is only fragmentary information on its magnitude and time dependence. In this work, spur or track H3O+ concentrations and the corresponding pH values are obtained from our calculated yields of H3O+ as a function of time, using Monte Carlo track chemistry simulations. We selected four impacting ions and we used two different spur and track models: 1) an isolated “spherical” spur model characteristic of low-LET radiation and 2) an axially homogeneous “cylindrical” track model for high-LET radiation. Very good agreement was found between our calculated time evolution of G(H3O+) in the radiolysis of pure, deaerated water by 300-MeV incident protons (which mimic 60Co gamma/fast electron irradiation) and the available experimental data at 25 °C. For all cases studied, an abrupt transient acid pH effect, which we call an “acid spike”, is observed during and shortly after the initial energy release. This acid-spike effect is virtually unexplored in water or in a cellular environment subject to the action of ionizing radiation, especially high-LET radiation. In this regard, this work raises a number of questions about the potential implications of this effect for radiobiology, some of which are briefly evoked. Our calculations were then extended to examine the effect of temperature from 25 to 350 °C on the yield of H3O+ ions that are formed in spurs of the low-LET radiolysis of water. The results showed an increasingly acidic spike response at higher temperatures. As many in-core processes in a water-cooled nuclear reactor critically depend on pH, the question here is whether these variations in acidity, even highly localized and transitory, contribute to material corrosion and damage.

Cette thèse en informatique se situe dans le domaine des Environnements Informatiques pour l’Apprentissage Humain (EIAH). Dans ce cadre, nous avons abordé la question de la personnalisation de l’apprentissage. Nos travaux de recherche consistaient à identifier un processus qui permette à la fois de personnaliser des séances de travail sur papier et des séances de travail sur des logiciels pédagogiques. Nous souhaitions que ce processus permette de prendre en compte les spécificités de chaque apprenant en s’appuyant sur son profil, mais qu’il prenne également en compte les buts et les habitudes pédagogiques des enseignants. Enfin, nous souhaitions que ce processus soit implémentable dans un système externe aux logiciels à personnaliser. Notre problématique s’est donc décomposée en trois points : comment exploiter les profils d’apprenants pour prendre en compte les individualités des apprenants ? Comment adapter une activité pour prendre en compte les besoins et habitudes pédagogiques d’un enseignant ? Et enfin, comment attribuer une activité à un apprenant ? Pour répondre au premier point, nous avons proposé le modèle cPMDL. Ce complément du langage de modélisation des profils PMDL permet de contraindre les profils des apprenants afin de sélectionner ceux ayant les caractéristiques requises par les contraintes. cPMDL nous permet donc d’exploiter les informations contenues dans les profils au sein du processus de personnalisation. Pour répondre au deuxième point, nous avons proposé l’approche GEPPETO. Cette approche s’appuie sur des modèles et des processus génériques permettant d’adapter les activités en fonction des intentions pédagogiques des enseignants grâce à la définition de contraintes sur les activités. Nous avons décliné cette approche pour permettre l’adaptation des activités papier (GEPPETOP), ainsi que pour l’adaptation des activités logicielles et de la configuration des environnements qui les supportent (GEPPETOS). Pour répondre au troisième point, nous avons proposé le modèle PERSUA2 qui permet de lier les contraintes sur profils de cPMDL aux contraintes sur activités de GEPPETO. Ces liens, nommés règles d’affectation, sont ensuite hiérarchisés selon leur degré de priorité pour former une stratégie pédagogique qui sera associée { un ou plusieurs contextes d’utilisation. Nous avons mis en oeuvre ces différentes contributions théoriques dans Adapte, un module de l’environnement informatique du projet PERLEA. Le rôle de cet environnement est d’assister l’enseignant dans la gestion de profils créés par l’enseignant lui-même ou issus de logiciels pédagogiques. Adapte est l’une des exploitations possibles des profils : le module réalisé permet de fournir à chaque apprenant des activités adaptées à son profil tout en respectant les choix pédagogiques de son enseignant. Ces activités peuvent être des activités papier proposées par le système ou des activités logicielles personnalisées par Adapte, mais effectuées dans un autre EIAH. Ce module, pleinement opérationnel, a montré la faisabilité technique de nos contributions théoriques et nous a permis de conduire des mises à l'essai auprès d'enseignants / This thesis in computer science belongs to the field of Interactive Learning Environments (ILE). In this context, we have addressed the issue of personalization of learning. Our research has consisted in identifying a process allowing one to personalize both paper working sessions and working sessions on educational software. Our goal was to design a process able to take into account the specificities of each learner, based on their profiles, but also to take into account the pedagogical goals and habits of teachers. Moreover, we had to design this process such as it could be easily implemented in a software external to the system being personalized. Our problem was therefore decomposed into three points: how to use learners’ profiles to take the individuality of learners into account? How to adapt a pedagogical activity to take the teaching needs and habits of a teacher into account? And finally, how to assign an activity to a learner? To answer the first point, we have proposed the cPMDL model. This complement of the profiles modelling language PMDL allows one to constrain the learners’ profiles to select those with the characteristics required by the constraints. cPMDL allows us to exploit the information contained in the profiles during the personalization process. To answer the second point, we have proposed the GEPPETO approach. This approach relies on generic models and processes to adapt activities according to the teachers' intentions, by defining constraints on activities. We have instantiated this approach to enable on the one hand the adaptation of paper activities (GEPPETOP) and on the other hand to enable the adaptation of software activities and the adaptation of configuration of environments that support them (GEPPETOS). To address the third point, we have proposed the PERSUA2 model which links cPMDL constraints on profiles with GEPPETO constraints on activities. Next, these links, called assignment rules, are organized into a hierarchy according to their priority degree in order to form a pedagogical strategy. This pedagogical strategy is then associated with one or more contexts of use. We have implemented these different theoretical contributions in Adapte, a module of the environment associated to the PERLEA project. The role of this environment is to assist teachers in the management of profiles created by themselves or coming from pedagogical software. Adapte is one of the possible uses of profiles: the module developed provides each learner with activities suited to their profiles, while respecting the teaching choices of the teacher. These activities may be paper activities proposed by the system or software activities personalized by Adapte but made within another ILE. This module, fully operational, has demonstrated the technical feasibility of our theoretical contributions and has allowed us to conduct experiment with teachers.

L'étude de l'architecture à travers ses composantes domestique et monumentale permet d'appréhender directement le fonctionnement de la société qui l'a produite, car les conditions sociales ont une influence aussi déterminante dans l'histoire de l'architecture que les aspects plus techniques, comme la disponibilité des matériaux de construction et l'évolution des connaissances techniques. Au Levant sud, cette situation s'observe d'autant mieux au 3ème millénaire avant notre ère, car l'époque marque la première urbanisation de la région. Cette dernière est caractérisée par l'apparition de nouvelles formes architecturales et de nouvelles techniques de construction. Les changements architecturaux les plus importants apparaissent lors de la construction des fortifications et des palais au Bronze ancien II et III. Les différences d'architecture impliquent l'action de constructeurs différents. Dans le cas des maisons du Bronze ancien, les différences de qualité de construction indiquent que les maisons devaient être réalisées par des particuliers, à l'inverse, la construction des palais et des fortifications implique l'intervention de véritables architectes - les premiers - travaillant sur l'ordre de commanditaires ou d'élites.

North-West University in South Africa is committed to expanding use of learning technologies for contact and distance education students by augmenting the existing NWU teaching and learning policy with an e-learning policy. The School of Continuing Teacher Education at North-West University is currently training about 24 000 in-service teacher students through Open Distance Learning. Only a few students submit assignments in typed format and seldom electronically. Students rarely use electronic technologies to augment their learning, and the SCTE employs few to support students. This does not comply with the South African Government’s policy on e-Education that demands information and communication technology mastery in teacher training. The aim of this research was integration of learning technologies in open distance learning at SCTE NWU through recommendations compiled in a sociologically transformative emergent implementation framework. The researcher followed a concurrent mixed-method sociologically transformative approach, focussing on the use of technology for social empowerment to cross the digital divide, through a theoretical lens of ICT for development. The lived experience in the natural setting of distance education students, lecturers, and involved stakeholders was used as initial data collection, informed by a continuous literature study of emergent learning technology use. Purposeful sampling was used during participant selection. The role of the researcher was that of participant observer, interviewer, and human instrument, from a position of methodological pragmatism as a method of inquiry. Using a design-based research approach, the thesis addresses the main research question through five research papers; each addressing one of the sub-questions as design-based research cycles, while collectively addressing the research problem to address the main research question. Nonstandardised measuring instruments were developed based on themes identified from literature and the analysis of qualitative data. Significant barriers to population-wide ICT adoption exist. Strong intentions of perseverance in attaining functional computer literacy are evident. Support and enablement are required to promote trust to attempt using computers, necessary to obtain self-confidence through accomplishment. In this way perseverance to attain functional computer literacy may be cultivated. The study presents a model for intention to use, confidence, trust and perseverance in attaining computer literacy competence with statistically significant standardised regression weights. In terms of affective responses of students during computer literacy training, a twodimensional model for computer literacy learning emotions is presented. Perceptions during professional development produced a model for faculty development towards socially transformative learning technology integration for open distance learning. The researcher also presents a people-technology interaction in teaching and learning model in the fifth paper. A distinction is made between reactionary interventions and pre-emptive unobtrusive seamless support, based on requirements identified through bottom-up feedback listening to latent requests of participants. Technology-enhanced learning integration should be legitimised through visible commitment from the university as institution. Lecturer training, innovative planning of time issues, acquisition of appropriate infrastructure, buying in from the institution and IT support services, and support of teacher-students are all essential for evolvement towards an e-mature organisation for the delivery of ODL to vast numbers of newly industrialised context clients. / Thesis (PhD (Curriculum Development Innovation and Evaluation))--North-West University, Potchefstroom Campus, 2013

Preface - Biotechnology is generally considered to be the wave of the future. To facilitate accurate and rapid development of medication and treatments, it is critical that we are able to simulate the human body. One section of this complex model would be the human energy system. Pharmaceutical companies are currently pouring vast amounts of capital into research regarding general simulation of cellular structures, protein structures and bodily processes. Their aim is to develop treatments and medication for major diseases. Some of these diseases are epidemics like cancer, cardiovascular diseases, stress, obesity, etc. One of the most important causes of these diseases is poor blood glucose control. Current management methods for insulin dependent diabetes are limited to trial and error systems: clearly ineffective and prone to errors. It is critical that better management systems be developed, to ease the diabetic epidemic. The blood glucose control system is one of the major systems in the body, as we are in constant need of energy to facilitate the optimum functioning of the human body. This study makes use of a developed simulation model for the human energy system to ease the management of Diabetes mellitus, which is a malfunction of the human energy system. This dissertation is presented in two parts: The first part discusses the human energy simulation model, and the verification thereof, while the second presents possible applications of this model to ease the management of Diabetes. The human energy system simulation model - This section discusses the development and verification of the model. It also touches on the causes, and current methods, of managing diabetes, as well as the functioning of the human energy system. The human energy model is approached with the conservation of energy in mind. A top down model is developed, using data from independent studies to verify the model. Application of human energy simulation model - The human energy simulation model is of little use if the intended audience cannot use it: people suffering from malfunctioning energy systems. These include people having trouble with obesity, diabetes, cardiovascular disease, etc. To facilitate this, we need to provide a variety of products useable by this group of people. We propose a variety of ways in which the model can be used: Cellular phone applications, Personal digital assistants (PDAs) applications, as well as computer software. By making use of current technology, we generate a basic proof-of-concept application to demonstrate the intended functionality. / MIng (Mechanical Engineering) North-West University, Potchefstroom Campus, 2004

North-West University in South Africa is committed to expanding use of learning technologies for contact and distance education students by augmenting the existing NWU teaching and learning policy with an e-learning policy. The School of Continuing Teacher Education at North-West University is currently training about 24 000 in-service teacher students through Open Distance Learning. Only a few students submit assignments in typed format and seldom electronically. Students rarely use electronic technologies to augment their learning, and the SCTE employs few to support students. This does not comply with the South African Government’s policy on e-Education that demands information and communication technology mastery in teacher training. The aim of this research was integration of learning technologies in open distance learning at SCTE NWU through recommendations compiled in a sociologically transformative emergent implementation framework. The researcher followed a concurrent mixed-method sociologically transformative approach, focussing on the use of technology for social empowerment to cross the digital divide, through a theoretical lens of ICT for development. The lived experience in the natural setting of distance education students, lecturers, and involved stakeholders was used as initial data collection, informed by a continuous literature study of emergent learning technology use. Purposeful sampling was used during participant selection. The role of the researcher was that of participant observer, interviewer, and human instrument, from a position of methodological pragmatism as a method of inquiry. Using a design-based research approach, the thesis addresses the main research question through five research papers; each addressing one of the sub-questions as design-based research cycles, while collectively addressing the research problem to address the main research question. Nonstandardised measuring instruments were developed based on themes identified from literature and the analysis of qualitative data. Significant barriers to population-wide ICT adoption exist. Strong intentions of perseverance in attaining functional computer literacy are evident. Support and enablement are required to promote trust to attempt using computers, necessary to obtain self-confidence through accomplishment. In this way perseverance to attain functional computer literacy may be cultivated. The study presents a model for intention to use, confidence, trust and perseverance in attaining computer literacy competence with statistically significant standardised regression weights. In terms of affective responses of students during computer literacy training, a twodimensional model for computer literacy learning emotions is presented. Perceptions during professional development produced a model for faculty development towards socially transformative learning technology integration for open distance learning. The researcher also presents a people-technology interaction in teaching and learning model in the fifth paper. A distinction is made between reactionary interventions and pre-emptive unobtrusive seamless support, based on requirements identified through bottom-up feedback listening to latent requests of participants. Technology-enhanced learning integration should be legitimised through visible commitment from the university as institution. Lecturer training, innovative planning of time issues, acquisition of appropriate infrastructure, buying in from the institution and IT support services, and support of teacher-students are all essential for evolvement towards an e-mature organisation for the delivery of ODL to vast numbers of newly industrialised context clients. / Thesis (PhD (Curriculum Development Innovation and Evaluation))--North-West University, Potchefstroom Campus, 2013

Preface - Biotechnology is generally considered to be the wave of the future. To facilitate accurate and rapid development of medication and treatments, it is critical that we are able to simulate the human body. One section of this complex model would be the human energy system. Pharmaceutical companies are currently pouring vast amounts of capital into research regarding general simulation of cellular structures, protein structures and bodily processes. Their aim is to develop treatments and medication for major diseases. Some of these diseases are epidemics like cancer, cardiovascular diseases, stress, obesity, etc. One of the most important causes of these diseases is poor blood glucose control. Current management methods for insulin dependent diabetes are limited to trial and error systems: clearly ineffective and prone to errors. It is critical that better management systems be developed, to ease the diabetic epidemic. The blood glucose control system is one of the major systems in the body, as we are in constant need of energy to facilitate the optimum functioning of the human body. This study makes use of a developed simulation model for the human energy system to ease the management of Diabetes mellitus, which is a malfunction of the human energy system. This dissertation is presented in two parts: The first part discusses the human energy simulation model, and the verification thereof, while the second presents possible applications of this model to ease the management of Diabetes. The human energy system simulation model - This section discusses the development and verification of the model. It also touches on the causes, and current methods, of managing diabetes, as well as the functioning of the human energy system. The human energy model is approached with the conservation of energy in mind. A top down model is developed, using data from independent studies to verify the model. Application of human energy simulation model - The human energy simulation model is of little use if the intended audience cannot use it: people suffering from malfunctioning energy systems. These include people having trouble with obesity, diabetes, cardiovascular disease, etc. To facilitate this, we need to provide a variety of products useable by this group of people. We propose a variety of ways in which the model can be used: Cellular phone applications, Personal digital assistants (PDAs) applications, as well as computer software. By making use of current technology, we generate a basic proof-of-concept application to demonstrate the intended functionality. / MIng (Mechanical Engineering) North-West University, Potchefstroom Campus, 2004