Made available in DSpace on 2016-08-03T16:34:31Z (GMT). No. of bitstreams: 1 ECFerreira.pdf: 845142 bytes, checksum: e77019da6850908cff3683b0b780c547 (MD5) Previous issue date: 2013-12-09 / This study aimed to identify and describe associations between subjective well-being, construct formed by general satisfaction with life and positive and negative affects, and self-efficacy for drug abstinence in cocaine/crack in the process of withdrawal. Used to assess the variables, the Scales of Positive and Negative Affects, General Satisfaction with Life, Self-efficacy for Withdrawal of Drug Evaluation for Change, University of Rhode Island and a questionnaire on socio-demographic and socio-cultural. 70 men participated, cocaine/crack, young and low education. They were people of incomes of up to three minimum wages (63%) who were hospitalized more than once (65%), self-reported abstinence at the time of data collection. Participants had average levels of self-efficacy for abstinence from drugs, low levels of subjective well-being, and were satisfied with their lives. Calculations of Pearson correlation revealed no association between subjective well-being and self-efficacy for abstinence from drugs, including readiness to change drug use and subjective well-being, nor between readiness to change drug use and self-efficacy for abstinence drugs. Results of analysis of variance revealed no differences in the levels of subjective well-being among different groups of readiness for change nor between the mean self-efficacy for abstinence from drugs among different groupings of readiness for change in drug use. The discussion touched on the results of the fact that the admission of participants was voluntary or involuntary, length of stay, their stage of readiness to change their behavior of drug and the characteristics of their group withdrawal on the literature of the area. Finally, he pointed out, in conclusion, limitations and future research agenda. / Este estudo teve por objetivo identificar e descrever associações entre bem-estar subjetivo, construto formado por satisfação geral com a vida e afetos positivos e negativos,e autoeficáciapara abstinência de drogas em dependentes de cocaína/crack em processo de abstinência. Utilizou, para avaliar as variáveis, as Escalas de Afetos Positivos e Negativos, de Satisfação Geral com a Vida, de Autoeficácia para Abstinência de Drogas, de Avaliação para Mudança da Universidade de Rhode Island e um questionário de dados sócio-demográficos e socioculturais. Participaram 70 homens, dependentes de cocaína/crack, jovens e de baixa escolaridade.Eram pessoas de rendimentos de até três salários mínimos (63%), que foram internadas mais de uma vez (65%), autodeclaradas abstinentes no momento da coleta dos dados. Os participantes possuíam níveis médiosde autoeficácia para abstinência de drogas, níveis baixos de bem-estar subjetivo, e estavam satisfeitos com suas vidas. Cálculos de correlação de Pearson revelaram que não há associação entre bem-estar subjetivoe autoeficácia para abstinência de drogas, entre prontidão para mudança no consumo de drogas e bem-estar subjetivo, nem entre prontidão para mudança no consumo de drogas eautoeficácia para abstinência de drogas. Resultados de análise de variância revelaram que não houve diferençasnos níveis de bem-estar subjetivo entreos diferentes os agrupamentos de prontidão para mudanças nem entre as médias de autoeficácia para abstinência de drogas entre os diferentes agrupamentos de prontidão para mudanças no consumo de drogas. A discussão abordou os resultados diante do fato de a internação dos participantes ter sido involuntária ou voluntária, do tempo de internação, do seu estágio de prontidão para mudar seu comportamento de consumo de drogas e das características de seu grupo de abstinência diante da literatura da área. Finalmente, apontou, em conclusão, limitações e agenda de pesquisa futura.

This research contributes to understanding the attitudes of Russian politicians towards sex education in schools and the kind of argumentation styles they use to oppose it. The paper is based on a framing analysis of the arguments of two important opponents to sex education: Pavel Astakhov, a Russian politician and former Children’s Rights Commissioner from 2009 to 2016; and Yelena Mizulina, Chairman of the State Duma Committee on Family Affairs, Women and Children since 2008, using online media sources in a ten-year period (2011-2021). The analysis finds that Astakhov’s most used frames are the disapproval of children’s exposure to new, different attitudes, the interference in Russian traditions by the West and the spread of a gender discourse in Russia. Mizulina focuses mainly on the unfitness of teachers since sex education should only be addressed by parents, and on the “right age” to start talking about it with young people. From the results, both politicians seem to strongly oppose comprehensive sex education (CSE), but Astakhov proposes to adopt a type of abstinence-only curriculum (AO), while Mizulina tries to completely discourage sex education of any kind for school-aged children.

No description available.

The topic Needs of people addicted to drugs and alcohol to maintain succesful abstinence in aftercare was chosen. Aftercare is an important part of addiction treatment, but often overlooked and unused. The aim is to clarify the needs of abstinent persons addicted to alcohol and other non-alcohol drugs and their subsequent comparison. The thesis is divided into two parts, theoretical and practical. The theoretical part deals with the development of addiction, its diagnosis, description of drugs and treatments options. Chapters dealing with treatment are thoroughly discussed because of the individual usage during the treatment of addiction. Aftecare of addicted people and problems with relapse take place in this part of work. The second part deals with research focused on identifying the needs of addicted people to drugs and alcohol to maintain successful abstinence and their subsequent comparison. Clarifying of these needs can serve as a recommendation to other abstaining people or as a support to services in the system of aftercare to successful abstinence nowadays. KEYWORDS Addiction, addictive substances, drug addiction treatment, abstinence, relapse, aftercare for drug and alcohol rehab

Background Buprenorphine is a semi-synthetic opioid used for the treatment of opioid dependence. Opioid use, including buprenorphine, has been increasing in recent years, in the general population and in pregnant women. Consequently, there has been a rise in frequency of neonatal abstinence syndrome (NAS), associated with buprenorphine use during pregnancy. The purpose of this study was to investigate correlations between buprenorphine and buprenorphine-metabolite concentrations in cord blood and onset of NAS in buprenorphine exposed newborns. Methods Nineteen (19) newborns who met inclusion criteria were followed after birth until discharge in a double-blind non-intervention study, after maternal consent. Cord blood and tissue samples were collected and analyzed by liquid chromatography–mass spectrometry (LC–MS) for buprenorphine and metabolites. Simple and multiple logistic regressions were used to examine relationships between buprenorphine and buprenorphine metabolite concentrations in cord blood and onset of NAS, need for morphine therapy, and length of stay. Results Each increase in 5 ng/ml level of norbuprenorphine in cord blood increases odds of requiring treatment by morphine 2.5 times. Each increase in 5 ng/ml of buprenorphine-glucuronide decreases odds of receiving morphine by 57.7 %. Along with concentration of buprenorphine metabolites, birth weight and gestational age also play important roles, but not maternal buprenorphine dose. Conclusions LC–MS analysis of cord blood concentrations of buprenorphine and metabolites is an effective way to examine drug and metabolite levels in the infant at birth. Cord blood concentrations of the active norbuprenorphine metabolite and the inactive buprenorphine-glucuronide metabolite show promise in predicting necessity of treatment of NAS. These finding have implications in improving patient care and reducing healthcare costs if confirmed in a larger sample.

This review will focus on a systems medicine approach to neonatal abstinence syndrome (NAS). Systems medicine utilizes information gained from the application of “omics” technology and bioinformatics (1). The omic approaches we will emphasize include genomics, epigenomics, proteomics, and metabolomics. The goals of systems medicine are to provide clinically relevant and objective insights into disease diagnosis, prognosis, and stratification as well as pharmacological strategies and evidence-based individualized clinical guidance. Despite the increasing incidence of NAS and its societal and economic costs, there has been only a very modest emphasis on utilizing a systems medicine approach, and this has been primarily in the areas of genomics and epigenomics. As detailed below, proteomics and metabolomics hold great promise in advancing our knowledge of NAS and its treatment. Metabolomics, in particular, can provide a quantitative assessment of the exposome, which is a comprehensive picture of both internal and external environmental factors affecting health.

This survey research explores neonatal intensive care unit speech-language pathologists’ perceptions of infants with neonatal abstinence syndrome; specifically, how NAS affects infants’ feeding skills, along with structural and oral-motor characteristics. The findings of this research will contribute to this population’s information base. The results are expected to inform the field and current evidence-based practice care for infants with NAS.Learner Outcome(s): Explain Neonatal Abstinence Syndrome (NAS) Describe infants with NAS and how NAS affects the infants’ feeding skills from the perspective of Neonatal Intensive Care Unit (NICU) Speech-Language Pathologists (SLPs) Identify how SLPs in the NICU participate in intervention for infants with NAS and their families

The purpose of this review of review was to determine if inclusive and comprehensive formal sexual education is effective in promoting safer sex behaviors compared to abstinence only until marriage sexual education, for lesbian, gay, bisexual, transgender and questioning (LGBTQ) adolescents. Peer reviewed articles were retrieved from Cumulative Index to Nursing and Allied Health Literature (CINAHL), Educational Resources Information Center (ERIC), Elton B. Stephens Co. Host (Ebsco Host), Medical Literature On-line (Medline), Psychological Information Database (PsychINFO) and government released statistical information that was published from 2000-2017. Inclusion criteria of synthesized articles were based on formal sexual education aimed at adolescent populations, including focus on LGBTQ subgroups. The literature reviewed demonstrated abstinence only until marriage formal sexual education has minimal to no effects on LGBTQ adolescent’s sexual behaviors. Whereas, comprehensive and inclusive formal sexual education has been shown to increase condom use, delay first sexual interaction, and decrease number of sexual partners and teen pregnancy. In conclusion, the research indicates that individuals who have received comprehensive or inclusive formal sexual education have a greater chance of demonstrating safe sex behaviors compared to those who received abstinence only until marriage sexual education.

No description available.

Background and Aims: In India, alcohol per capita consumption (APC) has substantially increased over the past 2 decades. Although consumption does vary across the country, consistent state-level data are lacking. We aimed to identify all state-level alcohol exposure estimates since 2000 to (i) model consistent current drinking (CD) (12 months) prevalence estimates for all 36 states/union territories (UT) in 2019 and (ii) compare state-level CD trends with national-level APC trends. Design: A systematic review for studies on the Indian state-level prevalence of CD, lifetime abstinence (LA), alcohol use disorders (AUD) or the quantity of alcohol consumed among current drinkers (QU) was conducted. Subsequently, statistical modelling was applied. Setting: Data were collected and modelled for all Indian states/UTs. Participants: Studies since 2000 referring to the general adult population (≥15 years) of at least one Indian state/UT were eligible. The total sample size covered was 29 600 000 (males: females, 1:1.6). Measurements: Results on LA, AUD and QU were summarized descriptively. For (i) the state-, sex- and age-specific CD prevalence was estimated using random intercept fractional response models. For (ii) random intercept and slope models were performed. Findings: Of 2870 studies identified, 30 were retained for data extraction. LA, AUD and QU data were available for 31, 36 and 12 states/UTs, respectively. CD model estimates ranged from 6.4% (95% CI = 2.1%–18.1%; males) in Lakshadweep and 1.3% (95% CI = 0.7%–2.6%; females) in Delhi to 76.1% (95% CI = 68.1%–82.6%; males) and 63.7% (95% CI = 49.4%–75.7%; females) in Arunachal Pradesh. Over time, CD decreased in most states/UTs in the observed data, contradicting increasing national-level APC trends. Conclusions: Alcohol use (measured as consistent current drinking) in India has large regional variations, with alcohol consumption being most prevalent in the North-East, Chhattisgarh, Telangana, Himachal Pradesh, Punjab and Jharkhand.