Made available in DSpace on 2010-04-20T20:14:57Z (GMT). No. of bitstreams: 0 Previous issue date: 1997-04-07T00:00:00Z / A presente dissertação analisa o desempenho de quarenta fundos mútuos de ações brasileiros no período de agosto de 1990 a maio de 1996. As ferramentas usadas na avaliação desses fundos foram as obtidas nos três modelos -clássicos de Treynor, Sharpe e Jensen e o Modelo de Treynor e Mazuy, que também analisa habilidade de market timing dos administradores dos fundos. Além disso, examinamos estratégia de construção e administração de fundos, bem como analisamos algumas características e classificações desses fundos.

The aim of this survey is also to determine vaccination coverage in compulsory vaccination of kids in the first years of life, compliance of vaccine dose timing with vaccination schedule and reasons why some children were not vaccinated. Another goal is to analyse the reasons for some kids in the first years of life being vaccinated late and whether some kids in groups most at risk are vaccinated against tuberculosis. We used a quantitative research method in the form of a cross-sectional study comprised of data collection and analysis. Our research sample consisted of children born in the years 2009, 2010 and 2011 in České Budějovice district. The reason why we have chosen this particular group of children is that (if applicable vaccination schedule had been adhered to) they were supposed to be fully vaccinated against diphtheria, tetanus, whooping cough, haemophilus influenzae b, Hepatitis B virus, poliomyelitis (DTPHibHB). This group of 831 children (427 boys and 404 girls) have been chosen by random sampling from practising paediatricians. These selected physicians provided us with data about all children born in above mentioned years. The results showed that overall vaccination coverage for Infanrix Hexa vaccine (four doses) is 98.2% and 97.26% for Priorix vaccine (two doses). Vaccination coverage for tuberculosis in the years 2009 and 2010 was 90.05%. In the first years of life, up to 88.1% of newborns were vaccinated against tuberculosis ? at least, according to vaccination schedule (and applicable Order). In the first year of life, 99.9% of children have been given three doses of Infanrix Hexa vaccine against diphtheria, tetanus, whooping cough, poliomyelitis, Haemophilus influenzae b invasive disease and Hepatitis B virus. In the first eighteen months of life, 97.4% of children in analysed sample were given fourth dose of said vaccine. 68.6% of children were given the first dose of Priorix-Tetra vaccine in the first fifteen months of life. In the following six to ten months, 75.4% of children were given the second dose. Further analysis revealed that in 40.5% of analysed records some vaccine dose timings were not met. The most common reason for vaccination delay was the state of health of the child. Two instances of vaccination delay were also caused by the omissions of parents. In 2010, indication for vaccination against tuberculosis was recorded for one newborn. In 2011, for four children from the analysed sample vaccination against tuberculosis was recommended. In all cases, vaccination against tuberculosis has been carried out in calmetisation centre. Taking into account my study and its results I can safely assume that the goals of my diploma thesis have been met and the hypotheses set forth have been confirmed by the research.

No description available.

abstract: Alternative computation based on neural systems on a nanoscale device are of increasing interest because of the massive parallelism and scalability they provide. Neural based computation systems also offer defect finding and self healing capabilities. Traditional Von Neumann based architectures (which separate the memory and computation units) inherently suffer from the Von Neumann bottleneck whereby the processor is limited by the number of instructions it fetches. The clock driven based Von Neumann computer survived because of technology scaling. However as transistor scaling is slowly coming to an end with channel lengths becoming a few nanometers in length, processor speeds are beginning to saturate. This lead to the development of multi-core systems which process data in parallel, with each core being based on the Von Neumann architecture. The human brain has always been a mystery to scientists. Modern day super computers are outperformed by the human brain in certain computations. The brain occupies far less space and consumes a fraction of the power a super computer does with certain processes such as pattern recognition. Neuromorphic computing aims to mimic biological neural systems on silicon to exploit the massive parallelism that neural systems offer. Neuromorphic systems are event driven systems rather than being clock driven. One of the issues faced by neuromorphic computing was the area occupied by these circuits. With recent developments in the field of nanotechnology, memristive devices on a nanoscale have been developed and show a promising solution. Memristor based synapses can be up to three times smaller than Complementary Metal Oxide Semiconductor (CMOS) based synapses. In this thesis, the Programmable Metallization Cell (a memristive device) is used to prove a learning algorithm known as Spike Time Dependant Plasticity (STDP). This learning algorithm is an extension to Hebb’s learning rule in which the synapses weight can be altered by the relative timing of spikes across it. The synaptic weight with the memristor will be its conductance, and CMOS oscillator based circuits will be used to produce spikes that can modulate the memristor conductance by firing with different phases differences. / Dissertation/Thesis / Masters Thesis Electrical Engineering 2015

Made available in DSpace on 2014-12-17T15:36:40Z (GMT). No. of bitstreams: 1 BrunoSBG_DISSERT.pdf: 3965357 bytes, checksum: 7e3aabdd040d50db3f4557799b032b1d (MD5) Previous issue date: 2013-04-03 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / Circadian rhythms are variations in physiological processes that help living beings to adapt to environmental cycles. These rhythms are generated and are synchronized to the dark light cycle through the suprachiasmatic nucleus. The integrity of circadian rhythmicity has great implication on human health. Currently it is known that disturbances in circadian rhythms are related to some problems of today such as obesity, propensity for certain types of cancer and mental disorders for example. The circadian rhythmicity can be studied through experiments with animal models and in humans directly. In this work we use computational models to gather experimental results from the literature and explain the results of our laboratory. Another focus of this study was to analyze data rhythms of activity and rest obtained experimentally. Here we made a review on the use of variables used to analyze these data and finally propose an update on how to calculate these variables. Our models were able to reproduce the main experimental results in the literature and provided explanations for the results of experiments performed in our laboratory. The new variables used to analyze the rhythm of activity and rest in humans were more efficient to describe the fragmentation and synchronization of this rhythm. Therefore, the work contributed improving existing tools for the study of circadian rhythms in mammals / Os ritmos circadianos s?o varia??es em processos fisiol?gicos que auxiliam os seres vivos na adapta??o aos ciclos ambientais. Esses ritmos s?o gerados e se sincronizam ao ciclo claro escuro por meio do n?cleo supraquiasm?tico. A integridade da ritmicidade circadiana tem grande implica??o na sa?de dos seres humanos. Atualmente sabe-se que dist?rbios nos ritmos circadianos est?o relacionados com alguns problemas da atualidade como a obesidade, propens?o a determinados tipos de c?ncer e transtornos mentais por exemplo. A ritmicidade circadiana pode ser estudada por meio de experimentos com modelos animais e diretamente nos seres humanos. Nesse trabalho utilizamos modelos computacionais para reunir resultados experimentais da literatura e explicar resultados de nosso laborat?rio. Outro foco desse trabalho foi na an?lise de dados de ritmos de atividade e repouso obtidos experimentalmente. Aqui fizemos uma revis?o sobre o uso de vari?veis utilizadas para analisar esses dados e por ?ltimo propomos uma atualiza??o na forma de calcular essas vari?veis. Os nossos modelos foram capazes de reproduzir os principais resultados experimentais da literatura e nos forneceram explica??es para resultados de experimentos realizados em nosso laborat?rio. As novas vari?veis utilizadas para analisar o ritmo de atividade e repouso em humanos se mostraram mais eficiente para descrever a fragmenta??o e sincroniza??o desse ritmo. Assim esse trabalho contribuiu aperfei?oando as ferramentas existentes para o estudo da ritmicidade circadiana nos mam?feros

nÃo hà / Os comovimentos entre os preÃos de ativos sugerem a atuaÃÃo de influÃncias exÃgenas. No entanto, nÃo hà consenso na literatura sobre quais fatores econÃmicos sÃo determinantes. Neste estudo, investiga-se a sensibilidade dos Ãndices setoriais BM&FBOVESPA a mudanÃas nas expectativas dos participantes do mercado para as variÃveis econÃmicas constantes do RelatÃrio Focus. CompÃem a amostra os sete Ãndices setoriais com sÃrie completa para o perÃodo de janeiro de 2009 a junho de 2014, compreendendo 286 observaÃÃes semanais. A abordagem utilizada para a modelagem da mÃdia das sÃries dos Ãndices fundamenta-se na teoria de precificaÃÃo multifatorial, utilizando-se as variÃveis forward-looking acompanhadas nesse relatÃrio como candidatas a fatores. Dada a presenÃa de heterocedasticidade condicional nas sÃries de retornos dos Ãndices setoriais, propÃe-se o arcabouÃo GARCH para modelagem da volatilidade. Os resultados sugerem que algumas variÃveis de expectativas sÃo significativas para explicaÃÃo das variaÃÃes dos Ãndices setoriais brasileiros e que os modelos multifatoriais propostos podem gerar ganhos de previsÃo, evidenciados pela reduÃÃo do erro quadrÃtico mÃdio das projeÃÃes de retorno. / The co-movements among asset prices suggest the action of exogenous influences, however, there is no consensus in the literature about which economic factors are responsible. This study investigates the sensitivity of the sector indexes BM&FBOVESPA to changes in expectations of market participants to the constant economic variables Focus Report. Make up the sample the seven sectoral indexes with complete series for the period January 2009 to June 2014, comprising 286 weekly observations. The approach used for the average modeling of indexes of series is based on multifactor pricing theory, using the forward-looking variables accompanied this report as candidates for factors. Given the presence of conditional heteroskedasticity in the sector indexes return series, it is proposed to GARCH framework for modeling the volatility. The results suggest that some expectations variables are significant for explanation of variations in Brazilian industry indices and the proposed multifactor models of returns can generate prediction gains evidenced by reduced of mean squared error of the return predictions.

A capacidade de adaptação das respostas posturais automáticas de acordo com informações do contexto indica uma interação entre dois níveis de controle, em que o processamento cognitivo de alta ordem das características de uma perturbação iminente seria capaz de modular o controle postural em níveis inferiores do sistema sensoriomotor. Os estudos aqui propostos procuram responder quais informações sobre as características da perturbação são utilizadas pelo central set para modular as respostas posturais automáticas. A tarefa estudada consistiu na recuperação do equilíbrio da postura ereta em resposta à translação da base de suporte. No Experimento 1, foi avaliada a influência de dicas visuais sobre a amplitude de deslocamento da base de suporte em sequências repetitivas ou aleatórias de perturbação. No Experimento 2, a dica de amplitude de deslocamento foi dada por meio da sequência de perturbações, comparando-se tentativas repetidas em bloco, em sequência conhecida e em sequência aleatória. No Experimento 3, foi avaliado o efeito de incerteza tanto da amplitude da perturbação quanto do tempo de aplicação da perturbação. O Experimento 4 teve como propósito avaliar a interação entre dica temporal e tarefa cognitiva concomitante à recuperação do equilíbrio. Os resultados mostram que (a) informações prévias sobre a magnitude da perturbação postural parecem ser incapazes de modular respostas posturais automáticas; (b) modulação de respostas posturais automáticas a partir de uma sequência repetitiva de perturbações aparentemente está associada à adaptação do sistema sensoriomotor e não à participação de processamento cognitivo das características físicas da perturbação iminente; (c) previsibilidade temporal da perturbação postural induz uma otimização das respostas posturais automáticas; e (d) a execução de tarefa cognitiva no momento da perturbação inibe o ganho de estabilidade de respostas posturais automáticas conferido pela dica temporal. Como conclusão, parece haver uma limitação do processamento cognitivo em modular respostas posturais automáticas. Considerando-se que o conceito de central set expressa a noção de que processamento cognitivo de dicas contextuais é capaz de otimizar respostas posturais automáticas, nossos resultados sugerem a necessidade da revisão deste conceito amplamente empregado na literatura de controle postural / Adaptability of automatic postural responses according to context information indicates an interaction between two levels of control, in which the high-order cognitive processing of the perturbation characteristics would be able to modulate postural control in lower levels of the sensorimotor system. The studies proposed here intended to scrutinize what cues about the perturbation characteristics are used by the central set to modulate the automatic postural responses. The task studied consisted in the recovery of postural equilibrium in response to a posterior translation of the support base. In Experiment 1, it was evaluated the effect of precueing the displacement amplitude of the supporting base in repetitive or random perturbation sequences. In Experiment 2, precueing of the support base displacement was provided by the sequence of perturbations, comparing repetitive trials, known sequence and random sequence. In Experiment 3, we evaluated the effect of uncertainty about amplitude and time of perturbation. Experiment 4 aimed to evaluate the interaction of temporal precueing and a concurrent cognitive task on body equilibrium recovery. Results show that (a) previous information about perturbation magnitude seems to be unable to modulate automatic postural responses; (b) modulation of automatic postural responses from a repetitive sequence of perturbations is apparently associated with an adaptation of the sensorimotor system rather than to the participation of cognitive processing of the perturbation characteristics; (c) temporal predictability of the postural perturbation induces optimization of automatic postural responses; and (d) cognitive task execution at the time of the perturbation inhibits the gain of automatic postural responses stability provided by temporal precueing. As a conclusion, there seems to be a limitation of cognitive processing to modulate automatic postural responses. Considering that the concept of central set expresses the notion that cognitive processing of a contextual precue is able to optimize automatic postural responses, our results suggest the need for revision of this conceptualization widely used in the postural control literature

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No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_augusto_pich.pdf: 767723 bytes, checksum: 4cf8d4b0f7a299a3c983a45743c74b89 (MD5) Previous issue date: 2014-08-11 / Sem bolsa / As novas tecnologias OGM (Organismos Modificados Geneticamente) foram desenvolvidas para aumentar o potencial produtivo das culturas. O presente trabalho tem como objetivo avaliar a influência da aplicação de ácido giberélico na redução ou superação da senescência precoce das linhagens de milho amarelo geneticamente modificadas, estabelecendo a dose de AG3 mais adequada a ser aplicada. Para tanto foram feitos experimentos em duas épocas, onde foram avaliadas a produtividade e umidade de colheita. Na primeira época de plantio (outubro 2012) foram utilizadas cinco doses (0, 50, 100, 150, 200 mg/planta) de PRO-GIBB (100 g/Kg de AG3), aplicadas em dois períodos, quando as plantas estavam em estádio V10 e VT. Na segunda época de plantio (abril 2013) foram utilizadas 4 doses (0, 10, 30, 50 mg/planta) de PRO-GIBB (100 g/Kg de AG3), aplicadas em quatro períodos, quando as plantas estavam em estádio V10, VT, R2 e R4. Foram utilizadas duas linhagens da Syngenta Seeds LTDA NPBXXX6 e NPBXXX9 que foram semeadas com equipamento mecânico (trator e semeadora a vácuo). A população final de 85.000/ha foi obtida após realização de desbaste, este realizado 20 dias após emergência. Foram instaladas quatro repetições e cada parcela foi constituída de 4 linhas de 4 metros, sendo que o espaçamento utilizado entre as linhas foi de 0,70 metros. Em laboratório foi determinado o rendimento por unidade de área (Kg ha-1) e a umidade foi determinada utilizando aparelho portátil Dickey John modelo Multi-Grain. Conclui-se que para a linhagem NPBXXX6 a aplicação de 40 mg/planta de PRO-GIBB (340 gramas de AG3/há) parceladas em quatro aplicações de 10 mg/planta (85 gramas de AG3/há) aumenta a sua produtividade em até 33% em relação à testemunha. Para linhagem NPBXXX9 a aplicação da mesma dose de PRO-GIBB parcelada em quatro aplicações aumenta a sua produtividade em até 45% em relação à testemunha. Quanto à redução ou superação da senescência precoce houve aumento na umidade de colheita com aplicação de 40 mg/planta de PRO-GIBB (340 gramas de Ag3/há) parceladas em quatro aplicações somente para linhagem NPBXXX9 indicando aumento no ciclo da linhagem. / New GMOs (Genetically Modified Organisms) technologies were developed to increase the yield potential of crops. This study aims to evaluate the influence of the application of gibberellic acid in reducing or overcoming premature senescence of strains of genetically modified yellow corn, establishing the most appropriate dose of GA3 to be applied. For both experiments in two seasons, where productivity and harvest moisture were evaluated were made. In the first planting season (October 2012) 5 doses were used (0, 50, 100, 150, 200 mg / plant) of PRO-GIBB (100 g / kg GA3) applied in two periods, when the plants were in V10 and VT stadium. In the second growing season (April 2013) 4 doses (0, 10, 30, 50 mg / plant) of PRO-GIBB (100 g / kg AG3) were used, applied in four periods, when the plants were in V10 stadium , VT, R2 and R4. Two strains of Syngenta Seeds LTD NPBXXX6 NPBXXX9 and sown with mechanical equipment (tractor and seeder vacuum) were used. The final population of 85,000 / ha was obtained after performing thinning, this made 20 days after emergence. 4 replicates were installed and each plot consisted of four rows of four meters, and the spacing used between rows was 0.70 meters. In the laboratory the yield per unit area (kg ha-1) and moisture was determined was determined using John Dickey Model Multi-Grain handset. We conclude that for strain NPBXXX6 the application of 40 mg / plant-PRO GIBB (340 grams AG3 / ha) applied in four applications of 10 mg / plant (85 grams of AG3 / no) increases your productivity by up to 33% compared to control. For lineage NPBXXX9 the application of the same dose of PRO-GIBB split in four applications increases your productivity by up to 45% compared to control. As for the reduction or overcoming premature senescence there was an increase in moisture crop with application of 40 mg / plant-PRO GIBB (Ag3 340 grams / ha) applied in four applications only for lineage NPBXXX9 indicating an increase in the strain cycle.

This thesis will deal with problems and solutions of cross-platform developing using MoNo framework as a replacement of Microsoft .NET framework on Linux and Mac OS-X platforms. It will take in account matters such as limitations in the filesystem to problems with deploying released programs. It will also deal with demands of precise timing and the need of efficient code on precise tasks to construct a program used for creating data from recordings of animals. These animals is set to perform a task, for example exploring a labyrinth or running on a rod, and it is all recorded on video. These videos are later reviewed by an observer which transcripts the recordings into data based on predefined behaviors and the time and frequency with which the animal is expressing them.

This thesis will deal with problems and solutions of cross-platform developing using MoNo framework as a replacement of Microsoft .NET framework on Linux and Mac OS-X platforms. It will take in account matters such as limitations in the filesystem to problems with deploying released programs. It will also deal with demands of precise timing and the need of efficient code on precise tasks to construct a program used for creating data from recordings of animals. These animals is set to perform a task, for example exploring a labyrinth or running on a rod, and it is all recorded on video. These videos are later reviewed by an observer which transcripts the recordings into data based on predefined behaviors and the time and frequency with which the animal is expressing them.