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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Friedrich Hölderlin. Kritisch-historische Ausgabe von Franz Zinkernagel 1914– 1926 [Rezension]: Werkteil Gedichte, Lesarten und Erläuterungen mit dem Text.Burdorf, Dieter 17 July 2024 (has links)
Teil I: Herausgeberbericht mit Benutzung einer Briefedition von
Frank Hieronymus. Teil II: Edition als PDF
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Customer satisfaction in the food sector / Using causal analyses to measure service quality / Kundenzufriedenheit in der Ernährungswirtschaft / Messung der Service Qualität mithilfe von KausalanalysenLülfs-Baden, Frederike 29 January 2009 (has links)
No description available.
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Berufsausbildung in Deutschland und den USA / Institutionalisierung des dualen Berufsbildungssystems in vergleichender Perspektive / Vocational Education in Germany and the United States / Institutionalisation of the dual vocational education system in comparative perspectiveKreysing, Matthias 26 May 2003 (has links)
No description available.
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Zielgruppensegmente und Positionierungsstrategien für das Marketing von Premium-Lebensmitteln / Target group segments and positioning strategies for the marketing of premium productsLüth, Maren 19 May 2005 (has links)
No description available.
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Zwischen Sorgerecht und Unterhaltspflicht. / Determinanten väterlichen Sorgehandelns in Nachtrennungsfamilien an den Beispielen Deutschland, Großbritannien und Norwegen. / Between Custody Rights and Maintenance Duties. / Determinants of Non-resident Fathering in Germany, Great Britain and Norway.Marten, Carina 17 April 2008 (has links)
No description available.
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Öffentliche Videoüberwachung in den USA, Großbritannien und Deutschland / Ein Drei-Länder-Vergleich / Public Camera Surveillance in USA, Great Britain and Germany / A Three-Nation ComparisonLin, Chen-Yu 19 July 2006 (has links)
No description available.
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Die Politisierung der ethnischen Differenz / Ethnische Mobilisierung und Ethnopolitik in Estland seit der Perestrojka / The Politization of Ethnic Differences. / Ethnic mobilization and ethno-policy in Estonia after PerestrojkaDittmer, Stephanie 07 May 2003 (has links)
No description available.
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Intravital imaging of hemodynamic glomerular effects of enalapril or/and empagliflozin in STZ-diabetic miceKroeger, Hannah, Kessel, Friederike, Sradnick, Jan, Todorov, Vladimir, Gembardt, Florian, Hugo, Christian 30 May 2024 (has links)
Background: Diabetic kidney disease is the leading cause of end-stage renal disease. Administration of ACE inhibitors or/and SGLT2 inhibitors show renoprotective effects in diabetic and other kidney diseases. The underlying renoprotective mechanisms of SGLT2 inhibition, especially in combination with ACE inhibition, are incompletely understood. We used longitudinal intravital microscopy to directly elucidate glomerular hemodynamics on a single nephron level in response to the ACE inhibitor enalapril or/and the SGLT2 inhibitor empagliflozin.
Methods: Five weeks after the induction of diabetes by streptozotocin, male C57BL/6 mice were treated with enalapril, empagliflozin, enalapril/empagliflozin or placebo for 3 days. To identify hemodynamic regulation mechanisms, longitudinal intravital multiphoton microscopy was employed to measure single nephron glomerular filtration rate (snGFR) and afferent/efferent arteriole width.
Results: Diabetic mice presented a significant hyperfiltration. Compared to placebo treatment, snGFR was reduced in response to enalapril, empagliflozin, or enalapril/empagliflozin administration under diabetic conditions. While enalapril treatment caused significant dilation of the efferent arteriole (12.55 ± 1.46 µm vs. control 11.92 ± 1.04 µm, p < 0.05), empagliflozin led to a decreased afferent arteriole diameter (11.19 ± 2.55 µm vs. control 12.35 ± 1.32 µm, p < 0.05) in diabetic mice. Unexpectedly under diabetic conditions, the combined treatment with enalapril/empagliflozin had no effects on both afferent and efferent arteriole diameter change.
Conclusion: SGLT2 inhibition, besides ACE inhibition, is an essential hemodynamic regulator of glomerular filtration during diabetes mellitus. Nevertheless, additional mechanisms—independent from hemodynamic regulation—are involved in the nephroprotective effects especially of the combination therapy and should be further explored in future studies.
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