Thesis (M.A.)--Trinity Evangelical Divinity School, 1986. / Includes bibliographical references (leaves 93-103).

Thesis (doctoral)--Rheinische Friedrich-Wilhelms-Universität Bonn, 2000. / Date from cover. Includes bibliographical references (p. 77).

Thesis (Doctoral)--Universität Bonn, 1991. / Includes bibliographical references.

Zugl.: Bonn, Universiẗat, Diss., 1990.

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Agronomia e Medicina Veterinária, Programa de Pós-Graduação em Saúde Animal, 2014. / Submitted by Guimaraes Jacqueline (jacqueline.guimaraes@bce.unb.br) on 2014-10-02T13:00:36Z No. of bitstreams: 1 2014_ManuellaRodriguesDeSouzaMello.pdf: 681269 bytes, checksum: 245580771537987e3030e85ea75ecfa7 (MD5) / Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2014-10-02T13:01:16Z (GMT) No. of bitstreams: 1 2014_ManuellaRodriguesDeSouzaMello.pdf: 681269 bytes, checksum: 245580771537987e3030e85ea75ecfa7 (MD5) / Made available in DSpace on 2014-10-02T13:01:16Z (GMT). No. of bitstreams: 1 2014_ManuellaRodriguesDeSouzaMello.pdf: 681269 bytes, checksum: 245580771537987e3030e85ea75ecfa7 (MD5) / O recente aparecimento de bactérias produtoras de enzimas carbapenemases representa um problema de saúde pública relacionado com a ineficiência no tratamento de infecções nosocomiais. Além do aumento de isolados humanos, muitas pesquisas apontam o crescente número de bactérias multirresistentes não somente em ambientes hospitalares, mas também em isolados de animais, ambientes e afluentes. Entretanto, estudos direcionados para o potencial zoonótico ainda são limitados. O objetivo do presente estudo foi identificar cepas de Enterobacteriaceae e P. aeruginosa produtores de enzimas carbapenemases circulantes em ambientes veterinários. Foram isoladas 17 amostras provenientes de clínicas veterinárias e submetidas ao teste de difusão em disco com imipenem, ertapenem e meropenem. 11 cepas sugestivas da presença de carbapenemases, com halo ≤22 mm no antibiograma, foram submetidas ao Teste de Hodge Modificado. Todas as amostras foram negativas para o teste de Hodge Modificado. Apesar de não ter sido detectada fenotipicamente a expressão da enzima carbapenemase, a resistência aos carbapenêmicos pode estar relacionada a outro mecanismo de resistência adquirido. Portanto, considerando os crescentes relatos da disseminação de carbapenemases, em especial a KPC, o mapeamento das áreas onde bactérias multirresistentes estão presentes é vital para a elaboração de medidas de controle e manutenção da salubridade da população. ______________________________________________________________________________ ABSTRACT / The recent emergence of bacteria producing carbapenemase enzyme represents a public health issue related to the inefficiency in the treatment of nosocomial infections. In addition to the increased human isolates, current studies indicate the increasing number of multidrug-resistant bacteria not only in hospital settings, but also present in isolates from animals, common areas and affluents. However, studies on the zoonotic potential are still limited. The aim of this study was to identify strains of Enterobacteriaceae and P. aeruginosa producing carbapenemase enzymes in veterinary environments. 17 samples from veterinary clinics were isolated and examined through the disk diffusion test with imipenem, meropenem and ertapenem. 11 strains suggesting of the presence of carbapenemase with halo ≤ 22 mm on antibiograma were submitted to the modified Hodge test. All samples were negative for the modified Hodge test. Despite the expression of carbapenemase enzyme has not been phenotypically detected, the carbapenem resistance may be related to another mechanism of acquired resistance. Therefore, considering the increasing reports of the spread of carbapenemases, especially KPC, the mapping of areas where multidrug-resistant bacteria are present is vital for the development of control measures and maintenance of the population health.

In dieser Arbeit wird die de-Rham-Kohomologie für die Quantengruppen zu den vier klassischen Serien von Lie-Gruppen bestimmt und es wird der Hodgeschen Zerlegungssatz gezeigt. Als entscheidendes Mittel wurde der Laplace-Beltrami-Operator L für Woronowicz’ äußere Algebren entwickelt. Für transzendente Werte von q und reguläre Kalkülparameter z ist L diagonalisierbar. Für die obigen Quantengruppen bestimmen wir die Eigenwerte von L, die neben q und z von zwei integralen dominanten Gewichten abhängen. Wie im klassischen Fall wird die de-Rham-Kohomologie durch harmonische Formen repräsentiert. Jedoch entspricht nur im Fall der A-Serie jeder harmonischen Form auch eine de-Rham-Kohomologieklasse. Im Falle der B-, C- und D-Serien sind biinvariante Formen nicht notwendig geschlossen. Es gilt aber, dass jede biinvariante Form harmonisch ist. Das zweite Hauptresultat ist die Hodge-Zerlegung für die Quantengruppen GLq(N) und SLq(N): Ist der Kalkülparameter z regulär, so lässt sich jede Form eindeutig zerlegen in die Summe aus einem Rand, einem Korand und einem Kohomologierepräsentanten. Ferner gilt, analog zum klassischen Fall, dass die folgenden drei Formenräume übereinstimmen: die biinvarianten Formen, die harmonischen Formen und die de-Rham-Kohomologie. Für die orthogonalen und symplektischen Quantengruppen gibt es keine vollständige Hodge-Zerlegung. Nur für die Elemente, die im Bild des Laplace-Beltrami-Operators liegen, gibt es eine eindeutige Zerlegung in Rand und Korand. Für die Standardkalküle auf den Quantengruppen GLq(N) und SLq(N) wird die Größe von Woronowicz’ äußerer Algebra bestimmt. Es wird gezeigt, dass der Raum der linksinvarianten k-Formen (N² über k)-dimensional ist. Die Algebra der biinvarianten Formen ist graduiert kommutativ. Ihre Poincaré-Reihe ist (1+t)(1+t³) ... (1+t^(2N-1)). Biinvariante Formen sind geschlossen. / Consider one of the standard bicovariant first order differential calculi for the quantum groups GLq(N), SLq(N), SOq(N), or SPq(N), where q is a transcendental complex number. It is shown that the de Rham cohomology of Woronowicz' external algebra coincides with the de Rham cohomologies of its left-invariant, its right-invariant and its bi-invariant subcomplexes. In the cases GLq(N) and SLq(N), the cohomology ring is isomorphic to the left-invariant external algebra and to the vector space of harmonic forms. We prove a Hodge decomposition theorem in these cases. The main technical tool is the spectral decomposition of the quantum Laplace-Beltrami operator. As in the classical case all three spaces of differential forms coincide: bi- invariant forms, harmonic forms and the de-Rham-cohomology. For orthog- onal and symplectic quantum groups there is no complete Hodge decompo- sition. In case of the standard calculi on the quantum groups GLq(N) and SLq(N), the size of exterior algebra is computed. The space of left-invariant k-forms has dimension C(N², k) (binomial coefficient). The algebra of bi-invariant forms is graded commutative with Poincaré series (1+t)(1+t³) ... (1+t^(2N-1)). Bi-invariant forms are closed.

Dans cette thèse, on construit puis on étudie une classe d'exemples de variations de structure de Hodge (VSH) sur des variétés complexes compactes. Dans la première partie, on construit des variétés projectives lisses munies de VSH à partir de certaines familles de sections hyperplanes à singularités simples. Les deux parties suivantes correspondent à l'étude de ces VSH de deux points de vue différents: on montre d'abord que leur application des périodes est génériquement immersive, puis on utilise le théorème décomposition de M. Saito pour calculer certains invariants cohomologiques.

Cette thèse a pour objet l'étude de quelques propriétés arithmétiques et géométriques des variétés de Shimura orthogonales. Ces variétés apparaissent naturellement comme espaces de modules de structures de Hodge de type K3. Dans certains cas, elles paramètrent des objets géométriques tels que les surfaces K3 et leurs analogues en dimensions supérieures, les variétés hyperkähleriennes. Ce point de vue modulaire sera notre fil conducteur tout au long de ce mémoire. Ainsi, dans la première partie, on démontre un résultat d'équirépartition du lieu de Hodge dans les variations de structures de Hodge de type K3 au dessus d'une courbe complexe quasi-projective. Dans la deuxième partie, on étudie des analogues arithmétiques du résultat précédent. Un exemple d'énoncés qu'on obtient est le suivant: étant donnée une surface K3 définie sur un corps de nombres et ayant partout bonne réduction, alors sous certaine hypothèse d'approximation, il existe une spécialisation telle que le nombre de Picard géométrique croît strictement. Dans la troisième partie, on relie les problèmes du saut de nombre de Picard dans les familles de surfaces K3 à la question de construction de courbes rationnelles sur ces surfaces. Enfin, on étend un résultat de Bogomolov et Tschinkel. On montre notamment que toute surface K3 définie sur un corps algébriquement clos de caractéristique quelconque et admettant une fibration elliptique non-isotriviale contient une infinité de courbes rationnelles. / This thesis deals with some arithmetical and geometrical aspects of orthogonal Shimura varieties. These varieties appear naturally as moduli spaces of Hodge structures of K3 type. In some cases, they parametrize geometric objects as K3 surfaces and their analogous in higher dimensions, the hyperkähler varieties. This modular point of view will be our guiding principle throughout this dissertation. In the first part, we prove an equidistribution result of the Hodge locus in variations of Hodge structures of K3 type above complex quasi-projective curves. In the second part, we study analogous results in the arithemtic setting. An example of statements we get is the following: given a K3 surface having everywhere good reduction and satisfying an approximation hypothesis, there exists a specialization with strictly increasing geometric Picard rank. In both cases, our methods take advantage of the rich arithmetic, automorphic and geometric structure of orthogonal Shimura varieties as well as the Kuga-Satake construction that links them to moduli spaces of abelian varieties. Finally, we extend a result of Bogomolov and Tschinkel. In particular, we show that any K3 surface defined over an algebraically closed field of arbitrary characteristic and admitting a non-isotrivial elliptic fibration contains infinitely many rational curves.

No description available.

Orientador: Elizabeth Terezinha Gasparim / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Matemática Estatística e Computação Científica / Made available in DSpace on 2018-08-23T08:45:07Z (GMT). No. of bitstreams: 1 Callander_Brian_M.pdf: 1926930 bytes, checksum: 341dd0f9759ced382e138cd14fc4ae2c (MD5) Previous issue date: 2013 / Resumo: O propósito desta tese é estudar fibrações de Lefschetz simpléticas, nas quais os ciclos evanescentes são subvariedades Lagrangianas das fibras. Para a descrição da teoria de interseção dos ciclos evanescentes utilizamos cohomologia de Floer Lagrangiana, cujo conceito revemos nesta tese. Apresentamos três exemplos principais e de caráteres distintos: (1) twists de Dehn generalizados, (2) o "espelho" da reta projetiva, e (3) uma fibração numa órbita adjunta de sl(3,C). O terceiro destes exemplos é original e utiliza um teorema recente de Gasparim- Grama-San Martin / Abstract: The objective of this thesis is to study symplectic Lefschetz fibrations, in which the vanishing cycles are Lagrangian submanifolds of the fibres. In order to describe the intersection theory of vanishing cycles we use Lagrangian intersection Floer cohomology, which we review. We present three main examples of distinct characters: (1) generalized Dehn twists, (2) the "mirror" of the projective line, and (3) a fibration on an adjoint orbit of sl(3,C). The third of these examples is original and uses a recent theorem of Gasparim- Grama-San Martin / Mestrado / Matematica / Mestre em Matemática