The high speed transfer of information in materials with dimensions below the sub-diffraction limit is essential for future technological developments. Metallic nanoparticle (NP) waveguides serve a unique role in efficient energy transfer in this size regime. Light may be confined to metallic structures and propagate along the surface of the waveguide via propagating plasmon waves known as surface plasmon polaritons (SPPs). Plasmon propagation of energy in metallic structures is not perfect however and damping losses from the waveguide material lead to a characteristic exponential decay in the plasmon near field intensity. This decay length is known as the propagation length and serves as an excellent metric to compare various waveguide materials and structures to one another at particular excitation wavelengths. This thesis presents recent work in the development of a novel measurement technique termed bleach imaged plasmon propagation (BlIPP). BlIPP uses the photobleaching property of fluorophores and far field fluorescence microscopy to probe the near-field intensity of propagating plasmons and determine the propagation length. The experimental setup, image analysis, conditions, and application of BlIPP are developed within this thesis and an in depth review of the 1-photon photobleaching mechanism is also investigated. The BlIPP method is used to investigate long plasmon propagation lengths along straight chains of tightly packed Au NPs through the coupling of light to sub-radiant propagating modes, where radiative energy losses are suppressed. The findings of this work reveal, experimentally, the importance of small gap distances for the propagation of energy. Complex chain architectures are then explored using BlIPP measurements of tightly packed straight and bent chains of spherical silver NPs. We observe the highly efficient propagation of energy around sharp corners with no additional bending losses. The findings of this thesis demonstrate the advantages and capabilities of using BlIPP propagation length measurement. Further, BlIPP is used to reveal the advantage of coupling light to sub-radiant modes of NP chains, which demonstrate the ability to guide light efficiently across long distances and around complex structures, bringing us a step closer to the goal of applying plasmonic devices and circuitry in ultra compact opto-electronic devices.

This thesis involves systems for virtual presence in remote locations, a field referred to as telepresence. Recent image-based representations such as Google map's street view provide a familiar example. Several areas of research are open; such image-based representations are huge in size and the necessity to compress data efficiently for storage is inevitable. On the other hand, users are usually located in remote areas, and thus efficient transmission of the visual information is another issue of great importance. In this work, real-world images are used in preference to computer graphics representations, mainly due to the photorealism that they provide as well as to avoid the high computational cost required for simulating large-scale environments. The cubic format is selected for panoramas in this thesis. A major feature of the captured cubic-panoramic image datasets in this work is the assumption of static scenes, and major issues of the system are compression efficiency and random access for storage, as well as computational complexity for transmission upon remote users' requests. First, in order to enable smooth navigation across different view-points, a method for aligning cubic-panorama image datasets by using the geometry of the scene is proposed and tested. Feature detection and camera calibration are incorporated and unlike the existing method, which is limited to a pair of panoramas, our approach is applicable to datasets with a large number of panoramic images, with no need for extra numerical estimation. Second, the problem of cubic-panorama image dataset compression is addressed in a number of ways. Two state-of-the-art approaches, namely the standardized scheme of H.264 and a wavelet-based codec named Dirac, are used and compared for the application of virtual navigation in image based representations of real world environments. Different frame prediction structures and group of pictures lengths are investigated and compared for this new type of visual data. At this stage, based on the obtained results, an efficient prediction structure and bitstream syntax using features of the data as well as satisfying major requirements of the system are proposed. Third, we have proposed novel methods to address the important issue of disparity estimation. A client-server based scheme is assumed and a remote user is assumed to seek information at each navigation step. Considering the compression stage, a fast method that uses our previous work on the geometry of the scene as well as the proposed prediction structure together with the cubic format of panoramas is used to estimate disparity vectors efficiently. Considering the transmission stage, a new transcoding scheme is introduced and a number of different frame-format conversion scenarios are addressed towards the goal of free navigation. Different types of navigation scenarios including forward or backward navigation, as well as user pan, tilt, and zoom are addressed. In all the aforementioned cases, results are compared both visually through error images and videos as well as using the objective measures. Altogether free navigation within the captured panoramic image datasets will be facilitated using our work and it can be incorporated in state-of-the-art of emerging cubic-panorama image dataset compression/transmission schemes.

This thesis involves systems for virtual presence in remote locations, a field referred to as telepresence. Recent image-based representations such as Google map's street view provide a familiar example. Several areas of research are open; such image-based representations are huge in size and the necessity to compress data efficiently for storage is inevitable. On the other hand, users are usually located in remote areas, and thus efficient transmission of the visual information is another issue of great importance. In this work, real-world images are used in preference to computer graphics representations, mainly due to the photorealism that they provide as well as to avoid the high computational cost required for simulating large-scale environments. The cubic format is selected for panoramas in this thesis. A major feature of the captured cubic-panoramic image datasets in this work is the assumption of static scenes, and major issues of the system are compression efficiency and random access for storage, as well as computational complexity for transmission upon remote users' requests. First, in order to enable smooth navigation across different view-points, a method for aligning cubic-panorama image datasets by using the geometry of the scene is proposed and tested. Feature detection and camera calibration are incorporated and unlike the existing method, which is limited to a pair of panoramas, our approach is applicable to datasets with a large number of panoramic images, with no need for extra numerical estimation. Second, the problem of cubic-panorama image dataset compression is addressed in a number of ways. Two state-of-the-art approaches, namely the standardized scheme of H.264 and a wavelet-based codec named Dirac, are used and compared for the application of virtual navigation in image based representations of real world environments. Different frame prediction structures and group of pictures lengths are investigated and compared for this new type of visual data. At this stage, based on the obtained results, an efficient prediction structure and bitstream syntax using features of the data as well as satisfying major requirements of the system are proposed. Third, we have proposed novel methods to address the important issue of disparity estimation. A client-server based scheme is assumed and a remote user is assumed to seek information at each navigation step. Considering the compression stage, a fast method that uses our previous work on the geometry of the scene as well as the proposed prediction structure together with the cubic format of panoramas is used to estimate disparity vectors efficiently. Considering the transmission stage, a new transcoding scheme is introduced and a number of different frame-format conversion scenarios are addressed towards the goal of free navigation. Different types of navigation scenarios including forward or backward navigation, as well as user pan, tilt, and zoom are addressed. In all the aforementioned cases, results are compared both visually through error images and videos as well as using the objective measures. Altogether free navigation within the captured panoramic image datasets will be facilitated using our work and it can be incorporated in state-of-the-art of emerging cubic-panorama image dataset compression/transmission schemes.

Each year, students who are newly enrolled in the University of Ottawa Cooperative Education Programs prepare for their first co-op work terms. In this period of pre-employment, students ask themselves important questions like, “What do I have to do to get a job?” and “What do I want to be?” As a co-op practitioner I am exposed to students’ experiences and the dilemmas they face but I still wondered what was hidden from my view and outside of my understanding. Thus, during one-on-one interviews that occurred prior to their first co-op work terms, six co-op students shared the photographs and stories of their co-op experiences with me and I shared my photographs and stories with them. Goffman’s (1959) theory of dramaturgy provided the theoretical framework to present, interpret, and understand the words and pictures that emerged from these interviews. What resulted were dramas, narratives, and allegories: six participant descriptions written as mini-biographies, verbatim transcripts prepared as a reader’s theatre script, and a set of five themes composed with vivid symbolism. The five metaphoric themes of co-op student experience are (a) journey, (b) circus, (c) metamorphosing, (d) anglers at sea, and (e) warriors. Taken together, what emerged was a deeper seeing and a richer understanding of what’s “really going on” in the time prior to students’ first co-op work terms (Goffman, 1974, p. 8) particularly with regards to legitimate peripheral participation, reflection, and experiential learning.

La radiothérapie est souvent utilisée pour contrôler la progression d'un cancer. Cependant, la mauvaise spécificité de ciblage de la plupart des techniques de radiothérapie peut entraîner une réponse clinique ambiguë. Une stratégie alternative - et complémentaire - est d'utiliser des matériaux possédant un numéro atomique élevé et qui peuvent ainsi agir en synergie avec les rayonnements ionisants pour améliorer le ratio thérapeutique de la radiothérapie. Dans ce contexte, une nanoparticule (NP) théranostique à base de gadolinium (Gd) est particulièrement adaptée pour fournir simultanément une plus grande précision en Imagerie par Résonance Magnétique (IRM) et une meilleure efficacité en radiothérapie clinique. Au cours de cette thèse, nous avons étudié d'un point de vue préclinique la pharmacocinétique et le métabolisme de ces NP chez des rongeurs et des primates non humains afin d'élucider leurs voies d'élimination et de calculer la dose sans effet nocif observé (NOAEL). De plus, nous avons démontré la capacité d'imagerie et de thérapie de ces particules sur un modèle de souris porteuses de mélanome cérébral, ceci afin d'appuyer le potentiel des NP pour la radiothérapie guidée par IRM en clinique. Ces travaux de thèse - ainsi que des résultats précédents - ont contribué au début d'un essai clinique actuellement en cours / Combinations of chemotherapy and radiotherapy are often used to control cancer progression. However, the poor targeting specificity of most chemotherapies and radiotherapies can cause toxicity and ambiguous clinical response. In particular, dose escalation in radiotherapy inevitably increases radiation exposure for some surroundings normal tissues and organs, putting them at risk for debilitating damage. An alternative – and complementary – strategy is the use of materials with high atomic numbers (Z) that strongly interact with low energy photons to produce photoelectrons and Auger electrons In this context, a new efficient type of gadolinium (Gd)-based theranostic agent (AGuIX®) has recently been developed by the team of Prof. Tillement for MRI-guided radiotherapy. AGuIX® is a 3-nm size nanoparticles of 9 kDa, consist of a polysiloxane network surrounded by Gd chelates. In this thesis, we investigated the elimination kinetics of AGuIX nanoparticle’s (NPs) from sub-cellular to whole organ scale using original and complementary techniques. This combination of techniques allows the exact mechanism of AGuIX NPs elimination to be elucidated. We reported the preclinical pharmacokinetics and toxicology studies of intravenous AGuIX NPs administration in healthy and atherosclerosis non-human primates (NHP), the goal of which is to demonstrate the safety of AGuIX NPs, in particular, for pre-clinical evaluation. Subsequently, we performed experimental and theoretical studies to investigate the radiosensitization of AGuIX NPs, in particular with B16F10 mouse melanoma as a model for brain metastases. After, we implemented experimental and theoretical studies to precisely understand the mechanism of this radiosensitization, we suggest additional mechanism, potentially caused by chemical and biological effects induced by the combination of Gd and radiation (i.e. high yield of radicals formation and combination, and bystander effect)

Reading comprehension is one of the basic learning skills that need to be learned in an early school years. The English language is generally introduced as early as Grade 2 level in township primary schools. Township learners are at most exposed to English as the language of learning and teaching (LoLt) for three years (Grade 5-7) before entering secondary school. Most township primary school learners enter secondary school with poor English language development and poor language proficiency. Reading comprehension is one of the problems experienced by most township secondary school learners. Lack of reading comprehension skills negatively affect their ability to constuct meaning from what they are reading. Reading support techniques or strategies need to be sought and developed to address the reading comprehension problems experienced by learners especially from the disadvantaged enviroment. ind it difficult to understand or interpret what they are reading. This research focused on the use of the imaging technique on a learning suport in developing reading comprehension skills of township secondary school learners. The emphasis was mainly on how this technique can be adapted in order to enhance its mastery in developing reading comprehension skills. This imaging technique is seen as a feasible technique in a holistic approach to develop reading comprehension skills. The imaging technique makes use of the formation of multisensory pictures during the reading process which are valuable in the independent construction of meaning. The use of imaging for reading enhances active learning and memory. The research was conducted with learners in Grade 9 in a secondary school in a Pretoria township. The participants in the research group experienced reading comprehension problems, lack of English language development and difficulty in the use of English as the (LoLT). Some of the learners in the research group appeared to be experiencing intellectual learning disability. The practical implementation of the imaging technique was done in twenty sessions. A control group attended twenty reading support sessions using a dictionary method, for the same texts. Qualitative and quantitative analyses of the results are performed and discussed. / Thesis (MEd (Educational Psychology))--University of Pretoria, 2004. / Educational Psychology / unrestricted

Each year, students who are newly enrolled in the University of Ottawa Cooperative Education Programs prepare for their first co-op work terms. In this period of pre-employment, students ask themselves important questions like, “What do I have to do to get a job?” and “What do I want to be?” As a co-op practitioner I am exposed to students’ experiences and the dilemmas they face but I still wondered what was hidden from my view and outside of my understanding. Thus, during one-on-one interviews that occurred prior to their first co-op work terms, six co-op students shared the photographs and stories of their co-op experiences with me and I shared my photographs and stories with them. Goffman’s (1959) theory of dramaturgy provided the theoretical framework to present, interpret, and understand the words and pictures that emerged from these interviews. What resulted were dramas, narratives, and allegories: six participant descriptions written as mini-biographies, verbatim transcripts prepared as a reader’s theatre script, and a set of five themes composed with vivid symbolism. The five metaphoric themes of co-op student experience are (a) journey, (b) circus, (c) metamorphosing, (d) anglers at sea, and (e) warriors. Taken together, what emerged was a deeper seeing and a richer understanding of what’s “really going on” in the time prior to students’ first co-op work terms (Goffman, 1974, p. 8) particularly with regards to legitimate peripheral participation, reflection, and experiential learning.

The Bachelor dissertation What do you mean national self-image? is a discourse analysis of the relationship between Swedish news providers. The study aims to investigate how Swedish-language print media interact with the main provider of Swedish news in English, The Local Sweden, and what it reports as the “essence” of the nation and its people.   The investigation has been conducted through the implementation of Ernesto Laclau’s and Chantal Mouffe’s discourse analysis and uses intertextuality, stereotypes, social representation, as well as nationalism and the imagined communities as its theoretical framework. The material selected for the analysis comprises publications by Swedish-language print media from the year of 2014, which engage in a dialogue with The Local Sweden beyond the generic interaction of news. The dissertation concludes that Swedish-language print media approach The Local Sweden’s news coverage in two ways: in agreement or in opposition of what has been reported. When The Local Sweden has published something with the intention of capturing the “essence” of Sweden and its people, they bring attention to the Swede’s hugging culture, their food and souvenirs, as well as their knowledge of language. The results of the study suggest that The Local Sweden manages to provide new information on the subjects, which then leads to Swedish-language print media responding with entire articles dedicated to these topics. The articles convey a sense of fascination and curiosity toward the findings and confirm that The Local Sweden has been correct in their observations. However, when The Local Sweden publishes something with the intention of presenting Swedish news rather than the specific “essence” of it, they find different angles in news stories than what has been covered by Swedish-language print media. The results of the study suggest that by doing so they set themselves apart and provoke Swedish-language print media into responding by incorporating a comment for and/or relating to them as a news provider. The comments convey that Swedish-language print media question The Local Sweden’s validity as a valuable member in covering Swedish news.