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Summaries in Afrikaans and English / Text in Afrikaans / Die tema van hierdie studie toon die kerkbegrip van Cyprianus aan as 'n spanning tussen die kerk as instituut en die kerk van die Gees. Hoofstuk een skets die invloed van Tertullianus as leermeester op Cyprianus. Tertullianus se kerkbegrip getuig self van spanning wat die produk is van 'n verandering van lidmaatskap vanaf die Katolieke kerk na die Montaniste. Tertullianus se kerkbegrip word vanuit twee perspektiewe belig. Eerstens vanuit 'n Katolieke, met 'n fokus op die fundering van die ware kerk en die mag van die kerk om sondes te kan vergewe. Tweedens vanuit 'n Montanistiese, wat die def iniering van die ware kerk en die mag van die kerk om sondes te kan vergewe eksklusief geestelik begrond. Hoofstuk twee skets die milieu waarbinne Cyprianus gearbei het. Dit sluit in 'n biografie van Cyprianus en die Afrika-religie en bevolking. Tweedens word die Europese invloed op Cyprianus se kerkbegrip aangedui. Die invloed van die Romeinse staatkundige model kan duidelik waargeneem word. Die grootste invloed was egter die Roomse kerklike model, weens die dinamika van die Roomse kerk. Hoofstuk drie skets die ekklesiologie van Cyprianus. Die spanning tussen die kerk as 'n instituut en die kerk van die Gees word aangedui deur 'n bespreking van die episkopaat; die betekenis van die biskop; Cyprianus se gesagsbegrip en sy perspektief op die primaat. Cyprianus se Bybelse verbintenis, sowel as die twee historiese lyne, naamlik die Pauliniese lyn en die Petruslyn, plaas sy uitspraak salus extra ecclesiam non est in perspektief. Cyprianus se kerkbegrip is primer 'n ekklesiologie van die Gees. In sy strewe na die eenheid van die kerk vind hy die kerk as instituut egter onontbeerlik. Spanning onstaan in sy poging om 'n sintese tussen die twee te vorm. / The theme of this study reveals the tension to be found between the church as institution and the church of the Spirit, in the ecclesiology of Cyprian. Chapter one shows the influence which Tertullian, as tutor, exerted on Cyprian. The ecclesiology of Tertullian also reveals the tension which is produced by the change of membership from Catholicism to Montanism. Tertullian's ecclesiology is highlighted from two different perspectives. Firstly from a Catholic view, with the focus on the fundamentals of the true church, and the authority and power of the church to forgive sins. Secondly, a Montanist view is proposed, which defines the true church, and the power it yields in forgiving sins, as being exclusively spiritual in nature. Chapter two describes the environment in which Cyprian worked. This includes a biography of Cyprian, as well as the African religion and people. Secondly the European influence is shown on Cyprian's ecclesiology. The influence exerted by the Roman state model is also clearly seen. The major influence though, was exercised by the Roman church model, on account of the dynamics of the Roman church. Chapter three describes Cyprian's ecclesiology. The tension between the church as institute and the church of the Spirit is revealed in a discussion on the episcopacy; the significance of the bishop; Cyprian's view on authority and his perspective on the primacy. Cyprian's biblical connection, as well as the two historical lines, namely the Pauline and Petrine lines, put his salus extra ecclesiam non est pronouncement in perspective. ecclesiology the unity of Cyprian's view is primarily that of a of the Spirit. In his striving towards the church though, he finds the church as institute to be indispensable. Tension develops in his endeavor to form a synthesis between the two. / Christian Spirituality, Church History and Missiology / D. Th.

Summaries in Afrikaans and English / Text in Afrikaans / Die tema van hierdie studie toon die kerkbegrip van Cyprianus aan as 'n spanning tussen die kerk as instituut en die kerk van die Gees. Hoofstuk een skets die invloed van Tertullianus as leermeester op Cyprianus. Tertullianus se kerkbegrip getuig self van spanning wat die produk is van 'n verandering van lidmaatskap vanaf die Katolieke kerk na die Montaniste. Tertullianus se kerkbegrip word vanuit twee perspektiewe belig. Eerstens vanuit 'n Katolieke, met 'n fokus op die fundering van die ware kerk en die mag van die kerk om sondes te kan vergewe. Tweedens vanuit 'n Montanistiese, wat die def iniering van die ware kerk en die mag van die kerk om sondes te kan vergewe eksklusief geestelik begrond. Hoofstuk twee skets die milieu waarbinne Cyprianus gearbei het. Dit sluit in 'n biografie van Cyprianus en die Afrika-religie en bevolking. Tweedens word die Europese invloed op Cyprianus se kerkbegrip aangedui. Die invloed van die Romeinse staatkundige model kan duidelik waargeneem word. Die grootste invloed was egter die Roomse kerklike model, weens die dinamika van die Roomse kerk. Hoofstuk drie skets die ekklesiologie van Cyprianus. Die spanning tussen die kerk as 'n instituut en die kerk van die Gees word aangedui deur 'n bespreking van die episkopaat; die betekenis van die biskop; Cyprianus se gesagsbegrip en sy perspektief op die primaat. Cyprianus se Bybelse verbintenis, sowel as die twee historiese lyne, naamlik die Pauliniese lyn en die Petruslyn, plaas sy uitspraak salus extra ecclesiam non est in perspektief. Cyprianus se kerkbegrip is primer 'n ekklesiologie van die Gees. In sy strewe na die eenheid van die kerk vind hy die kerk as instituut egter onontbeerlik. Spanning onstaan in sy poging om 'n sintese tussen die twee te vorm. / The theme of this study reveals the tension to be found between the church as institution and the church of the Spirit, in the ecclesiology of Cyprian. Chapter one shows the influence which Tertullian, as tutor, exerted on Cyprian. The ecclesiology of Tertullian also reveals the tension which is produced by the change of membership from Catholicism to Montanism. Tertullian's ecclesiology is highlighted from two different perspectives. Firstly from a Catholic view, with the focus on the fundamentals of the true church, and the authority and power of the church to forgive sins. Secondly, a Montanist view is proposed, which defines the true church, and the power it yields in forgiving sins, as being exclusively spiritual in nature. Chapter two describes the environment in which Cyprian worked. This includes a biography of Cyprian, as well as the African religion and people. Secondly the European influence is shown on Cyprian's ecclesiology. The influence exerted by the Roman state model is also clearly seen. The major influence though, was exercised by the Roman church model, on account of the dynamics of the Roman church. Chapter three describes Cyprian's ecclesiology. The tension between the church as institute and the church of the Spirit is revealed in a discussion on the episcopacy; the significance of the bishop; Cyprian's view on authority and his perspective on the primacy. Cyprian's biblical connection, as well as the two historical lines, namely the Pauline and Petrine lines, put his salus extra ecclesiam non est pronouncement in perspective. ecclesiology the unity of Cyprian's view is primarily that of a of the Spirit. In his striving towards the church though, he finds the church as institute to be indispensable. Tension develops in his endeavor to form a synthesis between the two. / Christian Spirituality, Church History and Missiology / D. Th.

L'objectif général de cette thèse est d'identifier l'influence des manifestations de la culture de l'organisation, en matière de valeurs et de pratiques organisationnelles, ainsi que de l'identité professionnelle et organisationnelle sur la performance professionnelle par les compétences, c'est-à-dire la performance compétente, au sein de la police. 916 policiers militaires du District Fédéral de tous les niveaux hiérarchiques ont participé à cette recherche. Des analyses factorielles exploratoires et confirmatoires ont été utilisées pour vérifier les évidences de la validité des mesures des constructions qui composent le modèle théorique. Les résultats trouvés suggèrent que les variables antécédentes (valeurs organisationnelles, pratiques organisationnelles, identité professionnelle et identité organisationnelle) permettent de faire des prédictions quant à la performance professionnelle. Aussi bien l'identité organisationnelle que l'identité professionnelle ont permis de faire une médiation (médiation simple et en chaîne) entre les dimensions sous-jacentes aux valeurs et aux pratiques organisationnelles et la performance au travail. Les pratiques organisationnelles ont plus de pouvoir de prédiction que les types de motivations par rapport à la performance professionnelle. Le test des modèles généraux et des modèles détaillés (modèles concurrents) a démontré que les constructions du modèle étaient stables et invariantes, ce qui permet leur utilisation dans différents contextes. Enfin, des limitations de recherche ont été montrées, leurs implications sont d'ordre théorique, méthodologique et de gestion, ce qui demande la mise en place de nouvelles recherches. / The purpose of this research was to identify and describe the influence of the manifestations of the culture, represented in this work by organizational values and practices, organizational and professional identity regarding the professional performance competencies of the professional in his service as a policeman. In total, 916 military police officers from Distrito Federal of all hierarchical levels of the police organization were questioned about organizational values, organizational practices, professional identity, organizational identity and professional performance competencies. The scales were tested using exploratory factorial analysis and confirmatory factorial analysis in order to validate the theoretical model using structural equation modeling. The results suggest that the variables of organizational values, organizational practices, professional identity and organizational identity can predict professional performance competencies. Organizational identity and professional identity have mediated (simple mediation and chain mediation) the relation between subjacent dimensions of values and organizational practices regarding performance at work. The organizational practices have predicted the professional performance competencies better than the organizational values subtypes. The tests of the general model and the parsimonious models (concurrent models) have demonstrated the stability and the invariance of the constructs of the model, indicating their usability in other contexts. After the conclusion are proposed the research limitations, theoretical, methodological and managerial implications, as well as an agenda to attend the gaps of the research.

This thesis deals with the options found in children's drawings symptoms that might help in uncovering school failure. The thesis consists of a theoretical and research part. The theoretical part is based on knowledge of the literature and the praxis. The first chapter describes the causes and symptoms of school failure. The second chapter deals with drawings and by drawing tests. There is described the methods and techniques used in my research in the third chapter. The research section contains the survey whose main objective was to confirm certain features of the drawing containing the failed student. The results of the survey were achieved through drawings, "Questionnaire of self - conception pupils' school success" by Z. Matějček and M. Vágnerová, analysis of average marks and interviews with teachers. The aim is to characterize the symptoms of failed student in the drawing.

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A experiência adquirida na realização de estudos epidemiológicos sobre o líquen plano oral associado à infecção crônica de hepatite C nos faz acreditar que as lesões atróficas/erosivas associadas ao vírus C tendem a apresentar características clínicas atípicas, por vezes exacerbadas e com resposta piorada à terapêutica proposta. Acreditando que existiria uma contrapartida histopatológica que justificasse o comportamento clinico evidenciado, o presente estudo propôs-se a estudar as populações de células T CD8+ e Foxp3+ no líquen plano oral associado à infecção crônica de hepatite C e compará-las com as populações do líquen plano oral idiopático. Foram selecionados 11 blocos de líquen plano oral associado à infecção crônica de hepatite C (Grupo 1) e 19 blocos parafinados de líquen plano oral idiopático (Grupo 2) dos arquivos do Laboratório de Patologia Cirúrgica da Disciplina de Patologia Bucal da Faculdade de Odontologia da Universidade de São Paulo e do Laboratório de Patologia Bucal, do Departamento de Patologia, da Universidade Federal de Santa Catarina. Para ambos os grupos foram realizados ensaios imunohistoquímicos com marcação dos anticorpos anti-CD8 e anti-Foxp3. As células marcadas foram contabilizadas e os resultados tratados estatisticamente. No Grupo 1, 64% dos pacientes eram do sexo feminino; 82% leucodermas e a média de idade era de 59 anos (variação 46 aos 75 anos). No Grupo 2, 63% dos pacientes eram do sexo feminino; 71% leucodermas e a média de idade era de 50,2 anos (variação 32 aos 66 anos). Quando os dados entre os Grupos 1 e 2 foram comparados, não houve correlação estatisticamente significante entre as contagens de células T CD8+, contagens de células T Foxp3+ ou na relação CD8+/Foxp3+ por mm2. As lesões atróficas/erosivas do Grupo 1 apresentaram densidade aumentada de células T CD8+ (p=0,034) e aumento na relação CD8+/Foxp3+ por mm2 (p=0,018), em relação ao Grupo 2. O estudo realizado não encontrou diferenças nas densidades de células T CD8+ e Foxp3+ no infiltrado do líquen plano oral associado ao vírus C em relação ao líquen plano idiopático. Por outro lado, as diferenças encontradas na quantidade de células T CD8+ e na relação CD8/Foxp3, em lesões atróficas/erosivas, parecem justificar as características clínicas evidenciadas em estudos prévios. / Our previous studies with oral lichen planus associated with chronic hepatitis C virus infection leads us to believe that atrophic/erosive forms of oral lesions tend to present unusual clinical features, sometimes exacerbated with a worsened response to treatment. Considering that this exacerbated aspect could indicate a similar exacerbate histopathological feature, the aim of this study was evaluated the populations of CD8(+) and Foxp3(+) T cells in oral lichen planus associated with chronic hepatitis C virus infection and correlated the findings with idiopathic forms of these lesions. The sample consisted of 11 cases of oral lichen planus associated with chronic hepatitis C virus infection (Group 1) and 19 cases of idiopathic oral lichen planus (Group 2) obtained from the Laboratories of Oral Pathology of the University of São Paulo and the Federal University of Santa Catarina. In both groups immunohistochemistry staining were performed using anti-CD8 and anti-Foxp3 antibodies. Positive cells were counted per area and the results were subjected to statistical analysis. In Group 1, 64% of the patients were female, 82% caucasian with mean age of 59 years (range from 46 to 75 years). In Group 2, 63% of the patients were female, 71% caucasian with mean age 50.2 years (range from 32 to 66 years). When Groups 1 and 2 were compared, no significant correlation between the frequencies of CD8(+), Foxp3(+) T cells and the ratio of CD8(+)/Foxp3(+) counts per mm2 was found. The atrophic/erosive lesions in Group 1 showed an increased frequency of CD8(+) T cells (p = 0.034) and an increased ratio of CD8(+)/Foxp3(+) counts per mm2 (p = 0.018) compared to Group 2. In conclusion, our data indicated no differences in the frequencies of CD8(+) and Foxp3(+) T cells in the inflammatory infiltrate of oral lichen planus associated with chronic hepatitis C virus infection compared to idiopathic lesions. However, the differences in the counts of CD8(+) T cells and the ratio of CD8(+)/Foxp3(+) in atrophic/erosive lesions seemed justify the clinical features in previous studies.

A porfiria aguda intermitente é uma doença autossômica dominante, decorrente de um distúrbio na via biossintética do heme, causado pela redução dos níveis da enzima uroporfirinogênio-I-sintetase. As manifestações clínicas envolvem o sistema nervoso periférico e o central. O diagnóstico baseia-se na excreção urinária elevada dos precursores das porfirinas ácido d-aminolevulínico e porfobilinogênio. O objetivo deste estudo foi analisar o quadro clínico apresentado por pacientes do Hospital das Clínicas de São Paulo com porfiria aguda intermitente, atendidos no período de janeiro de 1979 a dezembro de 1999. Foram avaliados 37 pacientes, com idades entre 6 e 48 anos, na proporção de 2,7 mulheres:1 homem. A faixa etária na qual ocorreu o maior número de crises foi a terceira década. Os pacientes apresentaram 63 crises, sendo que 13 deles também tiveram manifestações de caráter crônico. As manifestações clínicas mais freqüentes foram: dor abdominal, alteração da cor da urina, mudança no ritmo intestinal, déficit motor ou sensitivo-motor, vômitos, alteração do nível de consciência ou confusão mental, crises convulsivas, quadros disautonômicos cardio-vasculares e distúrbios psiquiátricos. As crises foram classificadas em leves, moderadas e graves, segundo critérios previamente estabelecidos. Todas as manifestações crônicas foram caracterizadas como leves. A neuropatia periférica motora ou sensitivo-motora nunca foi a manifestação inicial da crise de porfiria aguda intermitente. Houve correlação entre o tipo e o número de fatores precipitantes e a manifestação da neuropatia periférica motora ou sensitivo-motora, verificando-se que as crises nas quais ela está ausente foram em geral desencadeadas por apenas um fator, mais comumente de origem endócrina ou metabólica endógena, como período menstrual e jejum, enquanto que nas crises com neuropatia periférica houve a participação de vários fatores concomitantemente, sendo estes principalmente de origem exógena, como medicamentos. Os tratamentos mais utilizados nos surtos foram a administração de glicose, aumento da ingestão de carboidratos e o uso de fenotiazínicos. / Acute intermittent porphyria is an autosomal dominant disease, caused by a disturbance in the heme biosynthetic pathway, secondary to the reduction on the levels of uroporphyrinogen-I-synthetase enzyme. Clinical manifestations involve central and peripheral nervous system. The diagnosis is based on the elevated urinary excretion of porphyrins precursors d-aminolevulinic acid and porphobilinogen. The aim of this study was to analyze the clinical manifestations of acute intermittent porphyria in patients of the Hospital das Clínicas of São Paulo, seen between January 1979 and December 1999. 37 patients were studied, from 6 to 48 years old, with a rate of 2,7 women: 1 man. The age in which most of the crisis occurred was the third decade. The patients presented 63 crisis, and 13 of them presented also with chronic manifestations. The commonest clinical presentations were: abdominal pain, change in urine color, change in bowel habits, motor or sensory-motor deficit, vomiting, alteration of consciousness or mental confusion, convulsions, dysautonomic cardiovascular signs and psychiatric disorders. The crisis were classified as mild, moderate and severe, following criteria previously established. All chronic manifestations were characterized as mild. The peripheral motor or sensory-motor neuropathy was never the initial manifestation. Correlation was found between the kind and the number of precipitating factors, and the absence of peripheral neuropathy was in general related to just one factor, more commonly of endogenous endocrine or metabolic origin, like menstrual period and starvation, while in the crisis with peripheral neuropathy multiple factors were involved at the same time, these being of exogenous origin, like drugs. The most commonly used treatments were glucose administration, elevation of carbohydrate intake, and phenothiazines use.

A Doença do Refluxo Gastroesofágico (DRGE), comumente observada em crianças e adolescentes, é uma das causas intrínsecas mais frequentes do desgaste erosivo. O objetivo dessa pesquisa foi realizar um estudo exploratório e analítico em crianças e adolescentes com idade entre 10 e 15 anos com DRGE e identificar possíveis diferenças entre grupos Casos e Controles quanto à presença de halitose, fluxo salivar, pH, capacidade tampão da saliva, lesões de desgaste erosivo e cárie dentária, classificação socioeconômica e qualidade de vida. Trinta voluntários participaram da pesquisa, sendo 15 do grupo Caso e 15 do grupo Controle. Informações sexo e idade foram coletadas durante a anamnese. A presença de halitose foi verificada por meio de avaliação organoléptica. A avaliação salivar foi realizada pelo fluxo salivar estimulado e o pH e a capacidade tampão (técnica de Ericsson), medidos com um pHmetro digital. Para a classificação econômica, utilizou-se o Critério de Classificação Econômica Brasil 2014 (CCEB/2014). Os voluntários responderam um questionário sobre qualidade de vida, validado no brasil (Child-OIDP) para faixa etária de 11-14 anos de idade. Além disso, foi realizado exame clínico para detecção de desgaste erosivo e cárie dentária de acordo com os índices BEWE e ICDAS, respectivamente. Os dados foram analisados pelo software STATA 9. As variáveis categorizadas sexo, idade, halitose e classificação socioeconômica e as variáveis numéricas fluxo salivar, capacidade tampão e pH não apresentaram diferença estatística entre os grupos (p > 0,05). O grupo Caso apresentou diferença significativa comparado ao grupo Controle para as variáveis BEWE e ICDAS. Apenas o desgaste erosivo e a presença de lesões de cárie foram associados a DRGE. O BEWE e o ICDAS podem ser considerados métodos auxiliares para o diagnóstico de pacientes com refluxo patológico. A relação interdisciplinar entre os profissionais de saúde, em especial, cirurgiões dentistas e médicos gastroenterologistas, é essencial para melhor conduta médica-odontológica de pacientes com Doença do Refluxo Gastroesofágico. / Gastroesophageal Reflux Disease (GERD), commonly observed in children and adolescents is one of the most common intrinsic causes of the erosive wear. The aim of this research was to conduct an exploratory and analytical study in children and adolescents aged between 10 and 15 years with GERD and to identify possible differences between Cases and Controls groups for the presence of halitosis, salivary flow, pH, saliva buffering capacity, erosive wear and dental caries, socioeconomic classification and quality of life. Thirty volunteers participated in this study, but fifteen were in the Case group and fifteen were in the Control group. Information about age and sex were collected during the anamnesis. The presence of halitosis was verified by organoleptic evaluation. The salivary tests were performed by saliva stimulated salivary flow; pH and buffering capacity (by Ericsson technique) were measured with a digital pH meter. Economic classification was evaluated by Economic Classification Criteria Brazil 2014 (CCEB/2014). The volunteers answered a questionnaire about quality of life, validated in Brazil (Child-OIDP) for the age group of 11-14 years. Furthermore, the clinical examination was conducted to erosive wear and caries detection in accordance with BEWE and ICDAS index, respectively. The data were analysed by Stata 9.0 software. Categorical variables sex, age, halitosis and socioeconomic classification and numeric variables salivary flow, buffer capacity and pH had not statistical difference between groups (p > 0.05). The Case group had significant difference compared to the Control group using BEWE and ICDAS variables. Only erosive tooth wear and carious lesions were associated with GERD. The BEWE and ICDAS can complement the methods for the diagnosis of patients with pathological reflux. The interdisciplinary relationship between dentists and gastroenterologists is essential for better medical and dental management of patients with Gastroesophageal Reflux Disease.