Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-01-20T20:57:18Z No. of bitstreams: 1 AlessandraMendesPachecoGuerraVale_TESE.pdf: 6083940 bytes, checksum: 50490507cf0394240eea06786d58ff08 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-01-21T19:07:52Z (GMT) No. of bitstreams: 1 AlessandraMendesPachecoGuerraVale_TESE.pdf: 6083940 bytes, checksum: 50490507cf0394240eea06786d58ff08 (MD5) / Made available in DSpace on 2016-01-21T19:07:52Z (GMT). No. of bitstreams: 1 AlessandraMendesPachecoGuerraVale_TESE.pdf: 6083940 bytes, checksum: 50490507cf0394240eea06786d58ff08 (MD5) Previous issue date: 2014-12-26 / A detec??o autom?tica de componentes sangu?neos em imagens microsc?picas ? um importante t?pico da ?rea hematol?gica. A segmenta??o permite que os componentes sangu?neos sejam agrupados em ?reas comuns e a classifica??o diferencial dos leuc?citos possibilita que os mesmos sejam analisados separadamente. Com a segmenta??o autom?tica e classifica??o diferencial, contribui-se no processo de an?lise dos componentes sangu?neos, fornecendo ferramentas que propiciem a diminui??o do trabalho manual e o aumento da sua precis?o e efici?ncia. Utilizando t?cnicas de processamento digital de imagens associadas a uma abordagem fuzzy gen?rica e autom?tica, este trabalho apresenta dois Sistemas de Infer?ncia Fuzzy, definidos como I e II, para a segmenta??o autom?tica de componentes sangu?neos e classifica??o diferencial de leuc?citos, respectivamente, em imagens microsc?picas de esfrega?os. Utilizando o Sistema de Infer?ncia Fuzzy I, a t?cnica desenvolvida realiza a segmenta??o da imagem em quatro regi?es: n?cleo e citoplasma leucocit?rios, eritr?citos e ?rea de plasma e utilizando o Sistema de Infer?ncia Fuzzy II e os leuc?citos segmentados (n?cleo e citoplasma leucocit?rios), os classifica diferencialmente em cinco tipos: bas?filos, eosin?filos, linf?citos, mon?citos e neutr?filos. Foram utilizadas para testes 530 imagens contendo amostras microsc?picas de esfrega?os sangu?neos corados com m?todos variados. As imagens foram processadas e seus ?ndices de Acur?cia e Gold Standards foram calculados e comparados com os resultados manuais e com outros resultados encontrados na literatura para os mesmos problemas. Quanto ? segmenta??o, a t?cnica desenvolvida demonstrou percentuais de acur?cia de 97,31% para leuc?citos, 95,39% para eritr?citos e 95,06% para plasma sangu?neo. Quanto ? classifica??o diferencial, os percentuais variaram entre 92,98% e 98,39% para os diferentes tipos leucocit?rios. Al?m de promover a segmenta??o autom?tica e classifica??o diferencial, a t?cnica desenvolvida contribui ainda com defini??o de novos descritores e a constru??o de um banco de imagens utilizando diversos processos de colora??o hematol?gicos / Automatic detection of blood components is an important topic in the field of hematology. The segmentation is an important stage because it allows components to be grouped into common areas and processed separately and leukocyte differential classification enables them to be analyzed separately. With the auto-segmentation and differential classification, this work is contributing to the analysis process of blood components by providing tools that reduce the manual labor and increasing its accuracy and efficiency. Using techniques of digital image processing associated with a generic and automatic fuzzy approach, this work proposes two Fuzzy Inference Systems, defined as I and II, for autosegmentation of blood components and leukocyte differential classification, respectively, in microscopic images smears. Using the Fuzzy Inference System I, the proposed technique performs the segmentation of the image in four regions: the leukocyte?s nucleus and cytoplasm, erythrocyte and plasma area and using the Fuzzy Inference System II and the segmented leukocyte (nucleus and cytoplasm) classify them differentially in five types: basophils, eosinophils, lymphocytes, monocytes and neutrophils. Were used for testing 530 images containing microscopic samples of blood smears with different methods. The images were processed and its accuracy indices and Gold Standards were calculated and compared with the manual results and other results found at literature for the same problems. Regarding segmentation, a technique developed showed percentages of accuracy of 97.31% for leukocytes, 95.39% to erythrocytes and 95.06% for blood plasma. As for the differential classification, the percentage varied between 92.98% and 98.39% for the different leukocyte types. In addition to promoting auto-segmentation and differential classification, the proposed technique also contributes to the definition of new descriptors and the construction of an image database using various processes hematological staining

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-04T14:29:34Z No. of bitstreams: 1 FranciscoDaRochaBezerraJunior_DISSERT.pdf: 14313930 bytes, checksum: 6666840bda945bca422ef821ec0cb2f2 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-14T13:19:03Z (GMT) No. of bitstreams: 1 FranciscoDaRochaBezerraJunior_DISSERT.pdf: 14313930 bytes, checksum: 6666840bda945bca422ef821ec0cb2f2 (MD5) / Made available in DSpace on 2017-07-14T13:19:03Z (GMT). No. of bitstreams: 1 FranciscoDaRochaBezerraJunior_DISSERT.pdf: 14313930 bytes, checksum: 6666840bda945bca422ef821ec0cb2f2 (MD5) Previous issue date: 2016-08-02 / Nos ?ltimos anos, a pol?tica habitacional no pa?s tem se caracterizado por um modelo de interven??o marcado pela question?vel qualidade arquitet?nica e urban?stica da habita??o social, sobremaneira, voltada ?s popula??es da baixa renda. Desde o lan?amento do Programa Minha Casa Minha Vida ? PMCMV -, em 2009, as principais cr?ticas a este modelo de Programa Habitacional, recaem, sobretudo, no que se refere ?s solu??es apresentadas nos projetos desenvolvidos para habita??o de interesse social, uma vez que n?o refletem as necessidades dos diversos perfis de usu?rios, t?o pouco consideram as transforma??es na estrutura familiar ocorridas ao longo do tempo. Como desenvolver projetos para habita??o de interesse social que atendam ?s necessidades program?ticas e a din?mica dos diferentes tipos de usu?rios? Nesse sentido, o presente trabalho se insere no tema da Arquitetura da Habita??o de Interesse Social, tendo como objetivo geral elaborar um projeto de habita??o de interesse social, utilizando estrat?gias de flexibilidade, apresentando como universo de estudo o bairro de M?e Luiza, localizado no munic?pio de Natal/RN. Para tanto, foi realizada uma pesquisa bibliogr?fica, abordando o conceito de flexibilidade aplicado ao projeto da habita??o social, como forma de construir um referencial te?rico sobre o assunto; elabora??o de estudos de refer?ncia de projetos de habita??o que utilizam estrat?gias e t?cnicas construtivas aplicadas ? flexibilidade program?tica e funcional do edif?cio; identifica??o do perfil e demandas dos usu?rios atendidos pelo PMCMV, por meio do banco de dados da SEHARPE; an?lise dos condicionantes projetuais necess?rios ? elabora??o da proposta arquitet?nica; e o desenvolvimento de diferentes tipologias habitacionais e tipos de estrat?gias de flexibilidade relacionadas com espa?os coletivos e de sociabilidade. / In the last years, the housing policy in Brazil has been characterized by an intervention model marked by questionable architectural and urban quality of social housing, especially, when directed to low-income populations. Since the launch of the program named ?Minha Casa Minha Vida?- PMCMV in 2009, the main criticism to this model housing program are, especially, regarding to the solutions presented in projects developed for social housing, since it does not consider the needs of several user profiles, neither consider the changes in family structure that have occurred over time. How to develop projects for social housing that attend programmatic needs and dynamics of different types of users? Therefore, this work adresses the issue of social housing architecture, and aims the development of a social housing project, using flexible strategies, presenting as study universe the neighborhood named ?M?e Luiza? located in the city of Natal / RN. For such purpose, a literature survey was made addressing the concept of flexibility applied to social housing project as a way to build a theoretical background on the subject; development of reference studies of housing projects that use strategies and construction techniques applied to programmatic and functional flexibility of the building; identify the profile and demands of users served by PMCMV through the SEHARPE database; analysis of projective conditions necessary for the preparation of the architectural proposal; and the development of different housing typologies and types of flexibility strategies related to collectivity and sociability spaces.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-17T13:28:12Z No. of bitstreams: 1 MarcosPauloGomesPinheiro_TESE.pdf: 5533718 bytes, checksum: bf1ce7fe9e0014df2de63606b02f02ec (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-19T14:40:04Z (GMT) No. of bitstreams: 1 MarcosPauloGomesPinheiro_TESE.pdf: 5533718 bytes, checksum: bf1ce7fe9e0014df2de63606b02f02ec (MD5) / Made available in DSpace on 2017-07-19T14:40:04Z (GMT). No. of bitstreams: 1 MarcosPauloGomesPinheiro_TESE.pdf: 5533718 bytes, checksum: bf1ce7fe9e0014df2de63606b02f02ec (MD5) Previous issue date: 2017-02-13 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / As leishmanioses s?o graves problemas de sa?de p?blica no Brasil, causadas por protozo?rios do g?nero Leishmania transmitidos pelos flebotom?neos, pequenos insetos da ordem Diptera cujas f?meas s?o hemat?fagas. A leishmaniose visceral (LV) ou calazar, tem como principal vetor nas Am?ricas Lutzomyia longipalpis e Leishmania infantum como agente etiol?gico. No Brasil, a Regi?o Nordeste se destaca com a maior incid?ncia de casos de LV, principalmente entre as camadas mais desfavorecidas da sociedade. A leishmaniose tegumentar (LT) possui diferentes vetores e agentes etiol?gicos em todo o pa?s, tem ampla distribui??o, e apesar da menor gravidade, causa s?rias les?es desfigurantes e incapacitantes em todas as regi?es, principalmente na regi?o Norte. ? relevante a introdu??o de estrat?gias de preven??o que venham a modificar as a??es humanas por meio da informa??o e sensibiliza??o para o problema, sendo a literatura de cordel um instrumento educativo que atrai por sua conota??o l?dica e informal, despertando a aten??o das pessoas. O presente estudo buscou, portanto, conhecer os flebotom?neos de uma Unidade de Conserva??o da Mata Atl?ntica e seu entorno, bem como alguns fatores bi?ticos e abi?ticos relacionados ? sua ocorr?ncia, al?m de testar a utiliza??o do cordel como ferramenta informativa sobre o tema. O estudo aconteceu durante tr?s anos na ?rea interna e externa da Floresta Nacional (Flona) de N?sia Floresta, localizada no munic?pio de N?sia Floresta, regi?o metropolitana de Natal, Rio Grande do Norte, utilizando-se armadilhas Shannon e CDC. Foi produzido um cordel, em seu formato cl?ssico, intitulado ?Um bebedor de sangue na terra do mandacaru - Peleja contra o calazar?, para a??es de educa??o em sa?de com a popula??o residente no entorno da Flona e com alunos de escolas do munic?pio. Foram coletados e identificados 82.638 flebotom?neos das esp?cies Evandromyia evandroi, Evandromyia lenti, Evandromyia walkeri, Evandromyia sallesi, Lutzomyia longipalpis, Micropygomyia schreiberi, Nyssomyia intermedia, Nyssomyia whitmani, Psathyromyia abonnenci, Psathyromyia brasiliensis, Psathyromyia shannoni, Psychodopygus wellcomei e Sciopemyia sordellii. Os flebotom?neos foram mais abundantes junto ao solo do ambiente silvestre, apesar de tamb?m serem abundantes junto ?s copas e no peridomic?lio rural. Evandromyia walkeri foi a esp?cie mais abundante, representando 76% de todos os flebotom?neos coletados, sendo importante outras investiga??es acerca dessa esp?cie. Lutzomyia longipalpis, E. evandroi e E. lenti demonstraram prefer?ncia pelos ambientes antropizados. Esse estudo comprova a elevada antropofilia de P. wellcomei, que se mostra ativo durante quase todo o dia no ambiente silvestre, bem como sua rela??o com os meses chuvosos. Com base no conhecimento da bioecologia dos flebotom?neos vetores das leishmanioses na ?rea, espera-se que esse trabalho possa contribuir com estrat?gias de preven??o e controle das leishmanioses no Nordeste.O cordel teve grande aceita??o por parte dos estudantes da EJA e a experi?ncia demonstrou que esse pode ser um importante meio para a dissemina??o de informa??es acerca da leishmaniose visceral, regionalizando as estrat?gias, sensibilizando e divulgando um tema t?o importante em sa?de p?blica. / Leishmaniasis is a serious public health problem in Brazil, caused by protozoa of the genus Leishmania transmitted by sand flies, small insects of the order Diptera whose females are hematophagous. The main vector of visceral leishmaniasis (VL), or kala-azar, in the Americas is Lutzomyia longipalpis while Leishmania infantum is the etiological agent. In Brazil, the Northeastern Region stands out with the highest incidence of VL cases, especially among the most disadvantaged groups of society. Tegumentary leishmaniasis (TL) has different vectors and etiological agents throughout the country, a wide distribution, and despite its lower severity, it causes serious disfiguring and disabling lesions all over the country, especially in the North Region. It is relevant to introduce prevention strategies, through information and consciousness of the problem, in order to modify deleterious anthropic actions. Cordel folk literature has proved to be an educational instrument with potential use to address this issue, since it attracts by its playful and informal connotations and awakens the attention of people of different age groups. This study aimed, therefore, to know the sand flies fauna at an Atlantic Forest Conservation Unit and its surroundings, as well as some factors related to their occurrence, in addition to testing the use of cordel literature as an informative tool on the subject. The study took place over three years in the internal and external area of the N?sia Floresta National Forest (Flona) located in the city of N?sia Floresta, metropolitan region of Natal, Rio Grande do Norte, using Shannon and CDC traps. A cordel pamphlet in its classic format was produced, entitled "A blood drinker in the land of mandacaru - fight against kala-azar," for health educational activities among the population living in the vicinity of the Flona and students. The use of the cordel was validated through questionnaires applied to students of the Education of Young and Adults Program. The pamphlet approaches the transmission, symptoms, treatment and prophylaxis of the disease. There were collected and identified 82,638 sand flies of the species Evandromyia evandroi, Evandromyia lenti, Evandromyia walkeri, Evandromyia sallesi, Lutzomyia longipalpis, Micropygomyia schreiberi, Nyssomyia intermedia, Nyssomyia whitmani, Psathyromyia abonnenci, Psathyromyia brasiliensis, Psathyromyia shannoni, Psychodopygus wellcomei and Sciopemyia sordellii. Phlebotomines were more abundant near the soil of the wild environment, although they were also abundant near the canopy and in the rural peridomicille. L. walkeri was the most abundant species, representing 76% of all sandflies collected, and other investigations about this species are important. L. longipalpis, E. evandroi and E. lenti showed preference for anthropized environments. This study confirms the high anthropophilic behavior of P. wellcomei, which is active throughout the day in the wild, as well as its relationship with the rainy months. Based on the knowledge of the bioecology of sand flies vectors of leishmaniasis in the study area, as well as the factors involved in its occurrence, it is expected that this work may contribute to strategies for the prevention and control of leishmaniasis in Northeastern Brazil. The cordel literature was widely accepted by students and the experience has shown that this may be an important way for dissemination of information about visceral leishmaniasis. It is also desired that the regionalization of educational strategies through cordel literature can contribute to the dissemination of knowledge, sensitizing the community and disseminating such an important subject in public health. / 2019-05-04

Data de aprova??o retirada da vers?o impressa do trabalho. / Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2017-08-30T18:13:36Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) gelson_cerqueira_oliveira_junior.pdf: 2578577 bytes, checksum: 83cb8ab9378ea856fed151a0f1c1992d (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2017-08-30T18:51:12Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) gelson_cerqueira_oliveira_junior.pdf: 2578577 bytes, checksum: 83cb8ab9378ea856fed151a0f1c1992d (MD5) / Made available in DSpace on 2017-08-30T18:51:12Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) gelson_cerqueira_oliveira_junior.pdf: 2578577 bytes, checksum: 83cb8ab9378ea856fed151a0f1c1992d (MD5) Previous issue date: 2015 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Neste trabalho s?lica gel foi preparada a partir de areia de constru??o e carbonato de s?dio, apresentando uma ?rea de superf?cie de 378,68 m2/g, e volume de poro de 1,59x10-2 cm3/g. A fim de preparar diferentes catalisadores a base do mesmo material uma al?quota foi previamente aquecida a 400? C e outra a 700? C, as quais foram denominadas S400 e S700 que ap?s tratamento com H2SO4, deram origem a dois diferentes catalisadores, chamados de C400 e C700. Os catalisadores apresentaram volume total dos mesoporos de 0,23 cm3/g (C400) e 0,20 cm3/g (C700) e ?rea superficial de 31,06 m2/g (C400) e 23,10 m2/g (C700). Pela primeira vez foi utilizado ?cido de Bronsted imobilizado em s?lica para a convers?o de OGR em biodiesel. Ambos C400 e C700 apresentaram alta atividade na convers?o do ?leo e gordura residuais altamente ?cidos (13,7 mg de KOH) e com teor de ?gua de 0,58%, a biodiesel (?steres met?licos de ?cido graxo) em aproximadamente 99,4 %. As rea??es foram repetidas 4 vezes antes do catalisador perder sua atividade catal?tica. / Disserta??o (Mestrado) ? Programa de P?s-gradua??o em Biocombust?veis, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2015. / In this work, silica gel was prepared from building sand and sodium carbonate, having a surface area of 378.68 m2/g and pore volume of 1,59x10-2 cm3/g. In order to prepare different catalysts the basis of the same material aliquot was preheated to 400? C and another at 700? C, which were referred to as S400 and S700 which upon treatment with H2SO4, gave rise to two different catalysts, called C400 and C700. The catalysts showed total volume of mesopores of 0.23 cm3/g (C400) and 0.20 cm3/g (C700) and surface area of 31.06 m2/g (C400) and 23.10 m2/g (C700). For the first time was used Bronsted acid immobilized on silica OGR for conversion into biodiesel. Both C400 and C700 showed high activity in the oil conversion and highly acidic waste fat (13.7 mg of KOH) and 0.58% water content, biodiesel (fatty acid methyl esters) by approximately 99.4% . Reactions were repeated four times before the catalyst to lose its catalytic activity.

Made available in DSpace on 2014-12-17T14:13:22Z (GMT). No. of bitstreams: 1 GiuseppeAP.pdf: 289778 bytes, checksum: 0019c3f931b948d4ac6b9aa32d20ec37 (MD5) Previous issue date: 2007-08-16 / &#65279;The use of radionuclides has contributed for advances in Health Sciences, to research or to the diagnosis and/or treatment of diseases. These advances have been possible with the utilization of radiopharmaceuticals labeled with technetium-99m (99mTc). Stannous chloride (SnCl2) has the main reducing agent utilized to obtain radiopharmaceuticals labeled with technetium-99m. It has been reported that several natural or synthetic drugs are capable to alter the labeling of blood constituents with 99mTc, as well as the red blood cells morphology. The aim of this study was to evaluate possible alterations of Chrysobalanus icaco extract on the labeling of blood constituents with 99mTc, on the morphology of RBC of blood of Wistar rats, on the breakage of plasmid DNA and on the effects of stannous chloride on plasmid DNA. The results showed significant (P<0.05) alteration of the labeling of blood constituents with 99mTc, as well as, modification of the morphology and morphometry (perimeter/area ratio) of the RBC in presence of the extract. These data suggest that this abajeru extract could alter the labeling of blood constituents with 99mTc by its chelating/antioxidant action and/or effects on membrane structures. Moreover C. icaco extract altered the electrophoretic profile and decreased significantly (p<0.05) the effect of SnCl2 on plasmid DNA. The results obtained in this work could indicate a dose-dependent protective action against the SnCl2 and a genotoxic effect of C. icaco extract on plasmid DNA / &#65279;O uso de radionucl?deos tem contribu?do para avan?os relevantes em Ci?ncias da Sa?de, seja para pesquisa ou seja para o diagn?stico e/ou tratamento de doen?as. Muitos desses avan?os t?m sido poss?veis com a utiliza??o de radiof?rmacos marcados com tecn?cio-99m (99mTc). A marca??o desses radiof?rmacos necessita de um agente redutor e o cloreto estanoso tem sido o mais empregado. Tem sido descrito que diversas drogas naturais ou sint?ticas s?o capazes de interferir na marca??o de constituintes sangu?neos com 99mTc, assim como na morfologia das hem?cias. O objetivo deste estudo foi avaliar poss?veis interfer?ncias de um extrato de Chrysobalanus icaco (C. icaco) na marca??o dos constituintes sangu?neos com 99mTc, na morfologia de hem?cias do sangue de ratos Wistar, na quebra de DNA de plasm?dios e na a??o do cloreto estanoso no DNA plasmidial. Os resultados indicam que o extrato de C. icaco altera a marca??o de constituintes sangu?neos significativamente (p<0,05) com 99mTc, a morfologia e a morfometria (rela??o per?metro/?rea) das hem?cias, talvez por a??o quelante ou antioxidante e/ou por efeitos em estruturas da membrana envolvidas no transporte de ?ons. Al?m disso C. icaco altera o perfil eletrofor?tico e diminui significativamente (p<0.05) os efeitos do cloreto estanoso no DNA plasmidial. Estes ?ltimos resultados sugerem uma a??o protetora dose-dependente contra a a??o do cloreto estanoso e um efeito genot?xico do extrato de C. icaco no DNA plasmidial. O estudo tem car?ter multidisciplinar com a participa??o das seguintes ?reas do conhecimento: Radiobiologia, Bot?nica, Gen?tica, Fitoterapia e Hematologia

Made available in DSpace on 2014-12-17T14:13:40Z (GMT). No. of bitstreams: 1 CamilaGR.pdf: 488995 bytes, checksum: fa9e656a33d6c75d3226bec90875615a (MD5) Previous issue date: 2008-08-12 / Radiobiocomplexes are used in nuclear medicine to obtain images and to treat diseases. Blood constituents have been used as radiobiocomplexes. Natural or synthetic products can influence on the labeling of blood constituents with technetium-99m (99mTc), the morphology of red blood cells and on the stannous chloride (SnCl2) action on plasmid DNA. Sambucus australis and Sambucus nigra are used in popular culture for treating diseases. The aim of this work was to evaluate the effects of the extracts of Sambucus australis and Sambucus nigra on the labeling of blood constituents with 99mTc, on morphology of red blood cells of Wistar rats, on the topology of plasmids DNA and the action against the SnCl2 effects on the DNA of plasmids pBSK. On the labeling of blood constituents with 99mTc it was verified that both extracts were capable to decrease significantly the radioactivity in the cellular compartment and in the insoluble fraction of plasma. Sambucus australis also decreased the labeling of insoluble fraction of blood cells with 99mTc. Both extracts did not alter the morphology of red blood cells. Moreover, it was verified that Sambucus nigra did not alter the electrophoretic profile of plasmid DNA, but decreased the effect of SnCl2 on plasmid DNA. These last results sugest a genotoxic effect and a protective action of Sambucus nigra extract against the SnCl2 action on plasmid DNA. This work was developed with the contribution of several Departments of biomedical area of the Hospital Universit?rio Pedro Ernesto, of the UERJ, characterizing a multidisciplinary experimental research / Radiobiocomplexos s?o utilizados em medicina nuclear para obten??o de imagens e tratamento de doen?as. Constituintes sangu?neos t?m sido utilizados como radiobiocomplexos. Produtos naturais ou sint?ticos podem influenciar a marca??o de constituintes sang??neos com tecn?cio-99m (99mTc), a morfologia de hem?cias e a a??o do cloreto estanoso no DNA plasmidial. Sambucus australis e Sambucus nigra s?o utilizados na cultura popular para o tratamento de doen?as. O objetivo desse estudo foi avaliar os efeitos dos extratos de Sambucus australis e de Sambucus nigra na marca??o de constituintes sang??neos com 99mTc, na morfologia de hem?cias de ratos Wistar, na topologia do DNA plasmidial e sua a??o sobre os efeitos do cloreto estanoso no DNA de plasm?dios pBSK. Na marca??o de constituintes sang??neos com 99mTc verificou-se que os dois extratos foram capazes de diminuir significativamente a radioatividade no compartimento celular e na fra??o insol?vel do plasma. Sambucus australis diminuiu tamb?m a marca??o da fra??o insol?vel da c?lula com 99mTc. Os dois extratos n?o alteraram a morfologia das hem?cias. Al?m disso, foi verificado que um extrato de Sambucus nigra n?o alterou o perfil eletrofor?tico do DNA plasmidial, entretanto diminuiu os efeitos do cloreto estanoso no DNA plasmidial. Estes ?ltimos resultados sugerem um efeito genot?xico e uma a??o protetora do extrato de Sambucus nigra contra a a??o do cloreto estanoso no DNA plasmidial. Este trabalho foi realizado com a colabora??o de diversos Departamentos da ?rea biom?dica do Hospital Universit?rio Pedro Ernesto, da UERJ, caracterizando uma pesquisa experimental multidisciplinar

Made available in DSpace on 2014-12-17T15:03:33Z (GMT). No. of bitstreams: 1 AnneKFR_DISSERT.pdf: 446021 bytes, checksum: 247b6b8e1c94c43a75ed6fa260d6757a (MD5) Previous issue date: 2014-03-11 / A regi?o semi?rida sofre escassez h?drica. A fim de regularizar a disponibilidade h?drica nos per?odos de estiagem, s?o constru?das barragens. No entanto, a qualidade da ?gua armazenada tem sofrido os efeitos do descarte irregular de res?duos no meio ambiente e das atividades antr?picas exercidas nas bacias hidrogr?ficas. A degrada??o h?drica pode ser constatada a partir do monitoramento dos par?metros de qualidade da ?gua. Estes dados podem ser analisados atrav?s de m?todos estat?sticos tais como a An?lise de Componentes Principais e a an?lise de agrupamento, que seleciona indiv?duos com caracter?sticas semelhantes. O objetivo deste trabalho ? realizar oagrupamento dos reservat?rios do Rio Grande do Norte, com base nos par?metros de qualidade da ?gua, para a identifica??o de grupos homog?neos de reservat?rios em termos de fontes de polui??o. Ser?o objeto desse estudo as bacias Piranhas-A?u, Apodi-Mossor?, Trair?, Potengi e Cear?-Mirim. Os par?metros merc?rio, chumbo, cromo, f?sforo total, nitrog?nio total e zinco contribu?ram para a forma??o da primeira componente principal, que pode indicar polui??o por metais pesados; s?lidos totais, DBO, OD e cobre, para a segunda componente, que pode ser indicativo de polui??o por mat?ria org?nica e atividades antr?picas; e clorofila a , c?dmio e n?quel, para a terceira componente, que pode indicar eutrofiza??o e polui??o por metais pesados. De posse das componentes principais se procedeu o agrupamento dos reservat?rios, formando-se quatro grupos distintos. Os grupos 1 e 2 s?o constitu?dos por reservat?rios da Bacia Piranhas-A?u, que apresentou maiores valores de metais pesados. O grupo 3, constitu?do por reservat?rios das bacias Cear?-Mirim, Potengi e Trair?, apresentou maiores valores de DBO e s?lidostotais e o grupo 4 ? formado por reservat?rios da Bacia Apodi-Mossor?. Nas Bacias do Trar? e Piranhas-A?u deve ser coibido o lan?amento desordenado de efluentes e fontes de polui??o difusas, e implantado um sistema de coleta de esgoto para minimizar a polui??o por mat?ria org?nica

Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2017-06-09T19:03:28Z No. of bitstreams: 1 2016 - Patr?cia Ferreira de Andrade.pdf: 2739383 bytes, checksum: 4ef99b3a1e0c6cd9e74b662e4f2751c4 (MD5) / Made available in DSpace on 2017-06-09T19:03:28Z (GMT). No. of bitstreams: 1 2016 - Patr?cia Ferreira de Andrade.pdf: 2739383 bytes, checksum: 4ef99b3a1e0c6cd9e74b662e4f2751c4 (MD5) Previous issue date: 2016-02-24 / CAPES / This dissertation consisted in investigating the Municipal Plan of Education of Itagua?/RJ, which was reformulated in the year 2015 and will be current until the year 2025. For this purpose, acknowledging the relevance of the PME (2015) from Itaguai/RJ, (because it acts in a sense of re-orientating the education in the municipality) this study researched the reorientation of that document regarding pedagogical and educational assistance of the target-public students of the special education program of the municipality, and overall of the CEMAEE (Centro Municipal de Atendimento Educacional Especializado, in english "Municipal Centre of Specialized Educational Assistance"). Our researched issues were: Does the Municipal Plan of Education of Ituaguai (2015) contribute to the democratization process of the education system? How is the political-pedagogical organization set in the (re) orientation included in the PME (2015) of Itagua?, regarding the assistance to the target-public students in special education programs? Is the PME Itagua? (2015) in line with the PNE (National Education Plan)? Which are the perspectives of improvement that the PME Itagua? could establish in the CEMAEE's assistance? Which are the difficulties that the participants in this study have found for the implementation of the inclusive orientation for the target-public of the special education program? What do the participants of this study think/know about the current Public Policy of Inclusive Education concerning the special education target-public students? The methodological conception of this research was the "undissociability" between method and theory exposed in the Teor?a Critica (Critical Theory) of education. The thought of Theodor Adorno inspired our analysis, as well as Damasceno and Costa, commentators of his thought. Regarding the methodological procedures, we divided them in two moments, the first moment consisted in the documental analysis, in which we evaluated the previous PME of Itagua? (2010-2020) and the current (2015-2025) and we characterized the Documento de Forma??o (Formation Document) from 2010 from the CEMAEE. In the second moment, we accomplished the interviews with the subjects of the study, as follows: Ex-secretary of Education, Ex-sub-secretary of Education, Secretary of education, manager of the CEMAEE and the teacher of the CEMAEE, and we applied the characterization to them. In our final considerations, we identified that the PME (2015) represents a very important achievement for the education of the Municipality, since it presents political-pedagogical disposals that collaborate with the school inclusion of the target-public students of special education. Nevertheless Itagua? still faces challenges that raise obstacles to reach education for everyone, thus becoming urgent that what was instituted by the PME (2015) is implemented in the sphere of the institutive of the municipal network of Itagua?. We emphasize the importance of this and other researches that have the objective of studying the operational ability of the process of the school inclusion of the target-public individuals/students in the special education programs, in tune with the movement of democratization of the education. / Esta disserta??o tem como objeto de investiga??o o Plano Municipal de Educa??o de Itagua?/RJ, que foi reformulado no ano de 2015, com validade at? o ano de 2025. Para tal, tomando conhecimento da relev?ncia do PME (2015) de Itagua?, no que se refere a (re)orienta??o da educa??o do Munic?pio, este estudo pesquisou/problematizou os impactos deste documento no atendimento pedag?gico e educacional dos estudantes p?blico-alvo da educa??o especial do Munic?pio e, sobretudo, no CEMAEE (Centro Municipal de Atendimento Educacional Especializado). Nossas quest?es de investiga??o, derivadas de nosso objetivos, foram: O Plano Municipal de Educa??o de Itagua? (2015) contribui para o processo de democratiza??o no sistema de ensino? Como est? posta a organiza??o pol?tico-pedag?gica na (re) orienta??o inclusiva do PME (2015) de Itagua?, no que tange ao atendimento dos estudantes p?blico-alvo da educa??o especial? O PME de Itagua? (2015) est? em conson?ncia com o PNE? Quais as perspectivas de aperfei?oamento que o PME de Itagua? poder? instituir no atendimento do CEMAEE? Quais as dificuldades que os profissionais da educa??o, participantes deste estudo, tem encontrado para a implementa??o da orienta??o inclusiva para o p?blico-alvo da educa??o especial? O que pensam/sabem os sujeitos participantes do estudo sobre as atuais Pol?ticas p?blicas de Educa??o Inclusiva no que se refere aos estudantes p?blico-alvo da educa??o especial? A concep??o metodol?gica desta pesquisa se fundamenta na indissociabilidade entre teoria e m?todo posta na Teoria Cr?tica da educa??o. O pensamento de Theodor Adorno subsidiou nossas an?lises, assim como as reflex?es de Damasceno e Costa, comentadores de seu pensamento. Quanto aos instrumentos e procedimentos metodol?gicos, os dividimos em duas etapas: a primeira consistiu na an?lise documental, onde analisamos o PME de Itagua? (2010-2020) e o atual (2015-2025), al?m do Documento de Forma??o (2010) do CEMAEE. Na segunda etapa, realizamos as entrevistas com os sujeitos de estudo, a saber: Ex-secret?ria de educa??o, Ex-subsecret?ria de educa??o, Atual Secret?ria de educa??o, Gestor do CEMAEE e uma Docente do CEMAEE. Em nossas considera??es finais de pesquisa identificamos que o PME (2015) representa uma significativa conquista para a educa??o do Munic?pio, pois apresenta disposi??es pol?tico-pedag?gicas que colaboram com a inclus?o escolar de estudantes p?blico-alvo da educa??o especial. Entretanto, Itagua? ainda possui in?meros desafios que obstaculizam a afirma??o de uma educa??o para todos, tornando-se urgente que o institu?do no PME (2015) se implemente na esfera instituinte dos movimentos democr?ticos desta rede de ensino. Destacamos a import?ncia desta e outras pesquisas que possuem como objeto de estudo a operacionalidade do processo de inclus?o escolar de indiv?duos/estudantes p?blico-alvo da modalidade de educa??o especial, consent?neo ao movimento de democratiza??o da educa??o na contemporaneidade.

Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2017-07-21T18:25:26Z No. of bitstreams: 1 2017 - M?rcia Regina de Sant'Ana Maciel.pdf: 2074056 bytes, checksum: 266b01301517749928db36838481a716 (MD5) / Made available in DSpace on 2017-07-21T18:25:26Z (GMT). No. of bitstreams: 1 2017 - M?rcia Regina de Sant'Ana Maciel.pdf: 2074056 bytes, checksum: 266b01301517749928db36838481a716 (MD5) Previous issue date: 2017-02-21 / The present study analises the educational policy named National Pact for Literacy in the Right Age - PNAIC, regardingit?s contributions to the continued formation, the improvement of quality of alphabetization process and the teaching practices in the city of Belford Roxo, located in the State of Rio de Janeiro. The PNAIC is a course of continued formation of literacy teachers and the sistematic monitoring of its execution, by an organization structure suggested by MEC. The subject of this research was defined from the need of understanding if this continued formation has been important for the teacher, and which contributions can be considered significant in terms of their pedagogical praxis. For this we take as a reference the general principles proposed in this formation, which focus on the practice of reflexivity, mobilization of teaching knowledge, the constitution of professional identity, the socialization, the engagement and the collaboration. It was aimed in this research to contemplate,beyond the results measured through exams applied to the students, the qualitative results of the continued formation focusing the teacher. For so, different contexts of production and operationalization of the referred policy, compared with the speech of those involved directly with the continued formation: the coordinators, the advisors, and the local teachers. The basic theoretical reference is the analytical approach of the educational policies cycle, proposed by Stephen Ball. Therefore, we accomplished an study about the context of text production that informs about the referred educational policy, the context of its influence and the context of the continued formation practices of PNAIC. The present work consists of qualitative field research. We used as research methods the participant observationand bibliographical research, using the following resources for collecting data: interview and semi-structured questionnaire, logbook, and documental analysis. We concluded that, in the studied reality, the PNAIC continued formation, in the short period that happened, brought contributions to the improvement of the teaching quality through changes in the teaching practices, and these changes resulted in higher motivation, attention and participation from the students, bringing with it, advances in their learning. The continued formation follows problematizing characteristics, in which by way of exchanges of experiences and knowledges, the students are encouraged to think over the problem situation and to construct intervention strategies. However, some obstacles caused by external and internal factors were identified, requiring attention, mainly by the political authorities and the central PNAIC team, for the success of this policy in the network. / O presente estudo analisa a pol?tica educacional denominada Pacto Nacional pela Alfabetiza??o na Idade Certa - PNAIC, no que tange ?s suas contribui??es para a forma??o continuada, a melhoria da qualidade do processo de alfabetiza??o e as pr?ticas docentes no munic?pio de Belford Roxo, localizado na regi?o metropolitana da Baixada Fluminense do Estado do Rio de Janeiro. O PNAIC se desdobra em um curso de Forma??o Continuada de Professores Alfabetizadores e no acompanhamento sistem?tico de sua execu??o, por meio de uma estrutura organizacional sugerida pelo MEC. A tem?tica da pesquisa foi definida a partir da necessidade de compreender se esta forma??o tem sido importante para o professor e quais contribui??es podem ser consideradas significativas em termos de sua pr?xis pedag?gica. Para tanto tomamos como refer?ncia os princ?pios gerais propostos nessa forma??o, que incidem sobre a pr?tica da reflexividade, mobiliza??o dos saberes docentes, a constitui??o da identidade profissional, a socializa??o, o engajamento e a colabora??o. Objetivou-se nesta pesquisa contemplar, al?m dos resultados mensurados a partir das provas aplicadas aos alunos, os resultados qualitativos da forma??o com foco no professor. Para isso, foram analisados os diferentes contextos de produ??o e de operacionaliza??o da referida pol?tica, cotejada com os discursos dos envolvidos diretamente nesta forma??o: Coordenadora local, os Orientadores de estudo e os Professores locais. Seu referencial te?rico b?sico ? a abordagem anal?tica do ciclo de pol?ticas educacionais, proposta Stephen Ball. Portanto, realizamos um estudo sobre o contexto de produ??o do texto que informa a referida pol?tica educacional, o contexto da influ?ncia e o contexto da pr?tica da forma??o continuada do PNAIC. Este trabalho se constitui de pesquisa de campo do tipo qualitativa. Utilizamos como procedimentos de pesquisa a observa??o participante e a pesquisa bibliogr?fica, tendo por m?todos de coleta de dados: entrevista e question?rio semi-estruturado, di?rio de bordo e an?lise documental. Conclu?mos que, na realidade estudada, a forma??o continuada do PNAIC, mesmo no pouco tempo em que se sucedeu, trouxe contribui??es ? melhoria da qualidade do ensino atrav?s de mudan?as nas pr?ticas docentes. Estas mudan?as repercutiram em melhor motiva??o, participa??o e aten??o dos alunos trazendo com isso, avan?os nas suas aprendizagens. A forma??o segue caracter?stica problematizadora, onde por meio das trocas de experi?ncias e saberes, os cursistas s?o incentivados a refletir sobre as situa??es problemas e a construir estrat?gias de interven??o. Por?m alguns entraves causados por fatores externos e internos foram identificados, merecendo aten??o, principalmente por parte das autoridades pol?ticas e da equipe central municipal do PNAIC, para o sucesso dessa pol?tica na rede.

Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2017-07-25T18:37:04Z No. of bitstreams: 1 2015 - William Teixeira Alves.pdf: 1323115 bytes, checksum: 4bb8f0dadf6f166db7d7196979211740 (MD5) / Made available in DSpace on 2017-07-25T18:37:04Z (GMT). No. of bitstreams: 1 2015 - William Teixeira Alves.pdf: 1323115 bytes, checksum: 4bb8f0dadf6f166db7d7196979211740 (MD5) Previous issue date: 2015-02-23 / Accepting that changes in the current Brazilian educational system are possible, we point out the need to promote an effective training for teachers during graduate courses. The internship provides a perfect opportunity for interaction between theory and practice and offers the intern an opportunity to develop critical thought. This study aims at promoting a debate about the Teacher Graduation Course at UFRRJ, taking into consideration the new national guidelines for such courses; and underlining the importance of an initial training stage based on assisted practice guided by theoretical knowledge acquired during the course. Those, among others aspects, feed the debate on the importance and contributions of managed internship for the training of teachers in the aforementioned course. Therefore, in order to reach a better understanding of the relevance of Managed Internship for teacher education, we began by analyzing the legal documents that regulate the course, seeking possible gaps. Aside from that, we interviewed teachers and proposed questionnaires to students, whose narratives we analyzed. They all led us to the conclusion that Managed Internship can be an effective way to join theory and practice, since they are reflexive processes connected to teacher intervention in the classroom. This study does not intend to propose a standard to this practical teaching subject, but rather to ponder about aspects that can contribute to the development of a graduation process seen as a reflexive exercise about teaching. All this taking into consideration that throughout different historical periods, initial teacher graduation courses in Brazil have always considered internship as playing an essential role in the training of teachers, as well as in the development of teacher identity. / Por acreditar que mudan?as no atual sistema de educa??o brasileira s?o poss?veis, precisamos criar meios para uma forma??o reflexiva de professores/pedagogos. O tempo de est?gio proporciona uma integra??o entre a teoria e a pr?tica e oportuniza ao aluno-professor o desenvolvimento de um pensamento cr?tico. Este trabalho tem como objetivo promover uma discuss?o sobre a forma??o no Curso de Pedagogia proposta pela UFRRJ, considerando as novas diretrizes curriculares nacionais e a relev?ncia de uma forma??o inicial pautada numa pr?tica articulada ?s teorias e conhecimentos apreendidos ao longo de uma licenciatura. Esses, entre outros aspectos, impulsionam-me a discutir ainda a import?ncia e a contribui??o do Est?gio Supervisionado para a constru??o identit?ria do futuro profissional docente na referida institui??o. Assim, com intuito de melhor compreender o papel dos est?gios neste processo de forma??o de professores, buscou-se analisar as ideias preconizadas nos documentos legais, bem como os documentos institucionais que regulamentam o curso, a fim de discutir se ambos caminham em conson?ncia e ou apresentam disparidades. E, a partir deles, realizar uma an?lise das narrativas proferidas pelos licenciandos acerca do Est?gio supervisionado, por meio de question?rios. Neste sentido entendo o est?gio como o local da pr?tica-teoria-pr?tica, pois s?o processos reflexivos que permeiam a interven??o docente em sala de aula. Este trabalho n?o pretende impor um modelo para a disciplina Pr?tica de ensino, e sim refletir sobre os aspectos que possam contribuir para a implanta??o de um processo de forma??o que se constitua tamb?m num exerc?cio de reflex?o sobre a pr?tica docente. Isto levando em considera??o que no Brasil, ao longo do processo hist?rico de forma??o inicial de professores, independente dos distintos enfoques, a pr?tica advinda do Est?gio Supervisionado tem assumido um papel essencial na sua forma??o profissional, bem como na forma??o de sua identidade docente.