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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

Fatores associados a transtornos psiquiátricos no pós-parto

Kerber, Suzi Roseli January 2008 (has links)
OBJETIVO: Esta dissertação tem por objetivo apresentar o estudo da associação entre transtornos psiquiátricos pós-parto e fatores demográficos, psicossociais e relacionados à gestação e parto em uma amostra de base populacional de um bairro de Porto Alegre. MÉTODO: O estudo envolveu todas as mães de crianças nascidas em hospital público no bairro Vila Jardim, em Porto Alegre, de novembro de 1998 a dezembro de 1999. As famílias foram estudadas quando os bebês completaram quatro meses de idade. A saúde mental das mães e pais foi avaliada pelo Self Report Questionnaire (SRQ) e por entrevistas semi-estruturadas individuais e do casal. A Escala Avaliação Global do Funcionamento Relacional (GARF) do Manual Diagnóstico e Estatístico de Transtornos Mentais (DSM-IV) foi usada para aferir a qualidade do relacionamento do casal, do relacionamento materno com sua família de origem, com a família paterna e com a rede social. Para os outros fatores foram feitas perguntas diretas à mãe e ao pai da criança. RESULTADOS: Segundo a escala SRQ 34,45% das 148 mulheres entrevistadas apresentaram suspeita de transtorno psiquiátrico, sendo que a avaliação clínica feita por dois profissionais de saude mental que avaliavam independentemente utilizando os critérios diagnósticos do DSM-IV indicou um percentual de 54%. Sessenta e dois por cento das mulheres coabitavam com companheiro, sendo que estes também foram entrevistados. Dos 118 pais, 25,4% apresentaram suspeita de transtorno psiquiátrico, segundo a escala SRQ. Nesta população, o fato de coabitar ou não com companheiro não esteve associado com transtorno mental. Nesta pesquisa, na análise de regressão logística estudando a totalidade do grupo de mulheres os fatores que se mostraram relacionados com o desfecho (SRQ igual ou superior a sete ) foram a baixa renda familiar (p=0,017) e a presença de transtorno psiquiátrico materno no passado (p=0,043). Na regressão logística feita exclusivamente com as mulheres que viviam com companheiro, apenas a má qualidade da relação do casal (notas de 1 a 3 pela escala GARF) esteve associada à presença de transtornos psiquiátricos quatro meses após o parto (OR=7,34, p=0,001). CONCLUSÃO: Este estudo reforça a necessidade de verificar a presença de transtornos psiquiátricos da mãe nas consultas de puericultura, introduz dados sobre o pai e, especialmente, sobre a importância de avaliar rotineiramente a relação conjugal. / OBJECTIVE: To study the association between suspicion of psychiatric disorder and demographic, psychosocial factors, as well as those related to pregnancy and delivery, in a population-based sample of women from a circumscribed neighborhood in Porto Alegre. METHOD: This study included the mothers of all the children born in public hospitals in Vila Jardim, a district of Porto Alegre, Brazil, from November 1998 through December 1999. Families were assessed when infants were 4 months of age. Parents’ mental health was assessed using the Self-Report Questionnaire (SRQ) and individual and couple semi-structured interviews. The DSM-IV Global Assessment of Relational Functioning Scale was used to measure quality of couple relationship, of maternal relationship with the mother's family of origin, with paternal family and with social network. As to other factors, direct questions were asked to the child’s parents. RESULTS: According to the SRQ scale, 34.45% of all 148 interviewed women had suspicion of psychiatric disorder. The clinical assessment by two mental health professionals independently using DSM-IV criteria revealed a percentage of 54%. Sixty-two percent of women lived with partners, who were also interviewed. Of the 118 fathers, 25.4% had suspicion of psychiatric disorder, according to the SRQ scale. In this population, the fact of living or not with a partner was not associated with mental disorder. Analysis by logistic regression of the total group of women showed that factors associated with the main outcome (SRQ equal or higher than 7) were low family income (p = 0.017) and presence of previous maternal psychiatric disorder (p = 0.043). Logistic regression including only women living with a partner showed that poor marital relationship was associated with presence of psychiatric disorder, 4 months after delivery (OR = 7.34 p = 0.001). CONCLUSION: This study reinforces the need of investigating presence of maternal psychiatric disorder during childcare, introduces data on the father and especially on the importance of a routine assessment of the marital relationship.
22

Investigação da validade e precisão do psicodiagnóstico miocinético - PMK / Investigation of validity and reliability of the Myokinetic Psychodiagnosis PMK

Fábio Donini Conti 30 April 2014 (has links)
A presente pesquisa teve o objetivo de atualizar os parâmetros psicométricos do Psicodiagnóstico Miocinético PMK. Foi estudada uma amostra composta por 210 sujeitos adultos, todos destros, divididos em quatro grupos, um com 50 mulheres depressivas, um com 50 pacientes esquizofrênicos (35 homens e 15 mulheres), um com 50 reincidentes do sexo masculino do Sistema Prisional do Estado de São Paulo, que cometeram crimes de furto e/ou roubo e um grupo de controle, com 60 participantes (29 mulheres e 31 homens). Os instrumentos utilizados foram a entrevista clínica estruturada para o DSM-IV-TR, também conhecida como SCID-NP, com a finalidade de observar a presença de morbidades entre os presos e o grupo controle e de comorbidades entre os depressivos e esquizofrênicos, o Teste Palográfico, usado como critério no estudo de validade, e o PMK. A precisão foi obtida por meio do teste-reteste, somente com os protocolos da amostra controle e a validade, pelo método de grupos contrastantes e pelo método de validade simultânea. Para a precisão, foi calculado o coeficiente de correlação de Pearson e também utilizado o teste t para determinar se existiam diferenças entre os resultados das duas aplicações. Para os grupos contrastantes foi utilizada a ANOVA de um fator e o teste Post hoc de Tukey, com a finalidade de observar possíveis diferenças significativas das medidas do PMK entre os grupos. Nesta análise, os resultados foram comparados de acordo com o gênero dos participantes. Para a validade simultânea, os dados do Tônus Vital e da Agressividade do PMK e os da Produtividade, Direção das Linhas e Ganchos do Palográfico foram transformados em nota z e correlacionados por meio do coeficiente de correlação de Pearson, primeiramente com a amostra total e posteriormente com o grupo de depressivas e com o grupo de presos, separadamente. Os resultados do estudo de precisão indicaram que boa parte das medidas e dos traçados do PMK apresentou satisfatória estabilidade temporal, não sendo encontrada nenhuma diferença significativa entre teste e reteste. Ao todo, 64% das correlações foram superiores a 0,60, e as maiores médias das correlações foram para o Tônus Vital, a Agressividade e a Dimensão Tensional. As obtidas para o Predomínio Tensional foram as que apresentaram valores mais baixos, embora as correlações entre as aplicações tenham sido, todas, moderadas. Os resultados da validade entre grupos contrastantes demonstraram que, entre as mulheres, as diferenças significativas ocorreram, principalmente, no Tônus Vital, na Emotividade e na Dimensão Tensional. Entre os homens, na Agressividade, na Emotividade (com e sem sinal no DS) e na Dimensão Tensional. Os resultados da validade simultânea revelaram que as maiores correlações ocorreram entre as medidas da Agressividade do PMK com os Ganchos à direita do Palográfico. As correlações obtidas para o Tônus Vital também foram, na maior parte dos casos, significativas. A partir desses resultados, considerou-se que o PMK possui parâmetros científicos que permitem afirmar que ele é um teste preciso e válido para discriminar quadros clínicos de não clínicos / The present research had the purpose to update psychometric parameters of the Myokinetic Psychodiagnosis PMK. Participated a sample of 210 adult subjects, all right handed, divided into four groups, the first composed by 50 depressed women, the second by 50 schizophrenic patients (35 men and 15 women), the third by 50 male prisoners from the Prison System of the São Paulo State who had rescinded thefts and/or steals crimes, and a control group with 60 participants (29 women and 31 men). The instruments used were the Structured Clinical Interview for the DSM-IV-TR, also known as SCID-NP, in order to observe the presence of morbidity among prisoners and the control group and the co morbidity among depressed and schizophrenics. The Test Palográfico, was used as the validity criterion of the PMK test. The reliability was obtained by test-retest, restricted to the control sample and validity by the method of contrasting groups and the simultaneous validity. For the reliability was calculated the Pearson correlation coefficient and also the t test was used to verify if there were differences between the test-retest results. To evaluate the validity by contrasting groups it was used the one-way ANOVA and Pos hoc Tukey test, in order to determinate possible differences of PMK measures between groups. For simultaneous validity, data from PMK Vital Tonus and Aggressiveness and Productivity, Direction Lines and Hooks of Palográfico were transformed in z scores and then correlated by Pearson correlation coefficient, using data from the total sample and from the depressive group and the prisoner group independently. Results of the reliability study indicated that most of measures of PMK had a satisfactory temporal stability and no significant difference between test and retest means was found. Altogether, 64% of correlations were above 0.60 and higher means of correlations were for the Vital Tonus, Aggressiveness and Tensional Dimension. Correlations for Tensional Predominance showed the lowest values, although they can be considered moderate. Results of contrasting groups showed that, among women, significant differences were observed mainly in Vital Tonus, Emotionality and Tensional Dimension, and among men in Aggressiveness, Emotionality (with an without DS signal) and Tensional Dimension. The concurrent validity showed that significant correlations occurred mainly between PMK Aggressiveness measures and Palográfico Hooks at right. Vital Tonus correlations were in most cases significant. These results indicate that the PMK Test presents scientific parameters that allow to confirm that its a reliable and valid test to discriminate clinical cases from those non-clinical
23

Transtornos psiquiátricos menores em cuidadores familiares de usuários de Centros de Atenção Psicossocial do sul do Brasil / Minor psychiatric disorders in family members caregivers of clients at Psychosocial Attendance Center in southern Brazil

Quadros, Lenice de Castro Muniz de 09 November 2010 (has links)
Made available in DSpace on 2014-08-20T13:49:43Z (GMT). No. of bitstreams: 1 Dissertacao_LENICE.pdf: 600422 bytes, checksum: f234dc900847523fdd9aca8f1f62990a (MD5) Previous issue date: 2010-11-09 / The current Mental Health Policy in Brazil is based on the Law 10.216/02 and seeks the consolidation of a model of an open mental health care, community-based. By encouraging the creation of alternative services to asylum model, it is clear the inclusion of the user's mental health services family in the treatment, to provide user support and to receive specific care. It is worth noting that care for patients with mental disorder can lead to family burden which can lead to greater frequency of problems related to mental health. It is estimated that disorders related to mental health represent 12% of the global burden of disease (WHO, 2001). This study is a substudy of the CAPSUL project . Data collection osf the quantitative subproject was performed in 30 municipalities in the southern region (Rio Grande do Sul, Santa Catarina and Parana) for 14 pairs of interviewers, in the period from May to June 2006. This is a transversal design study aiming to determine the overall prevalence of minor psychiatric disorders and its association with sociodemographic variables and burden in family caregivers of CAPS users in southern Brazil. The outcome is the minor psychiatric disorders, assessed by the Brazilian version of the Self Report Questionnaire (SRQ-20) and the independent variables included sociodemographic characteristics, stressors and self-reported burden. We interviewed 936 caregivers. The prevalence of minor psychiatric disorders was associated with low education, having some health problems, presence of stressful events, being the sole caregiver and self-reported burden. The study helps to assess the mental health of caregivers for CAPS users, identifying patterns of occurrence, associated factors and vulnerable groups. It is also useful in designing policies aimed at carers of users of health services who have chronic diseases, including interventions for mental health promotion, risk prevention and control of diseases. Finally there is the potential for comprehensive epidemiological studies in assessing the health of family caregivers of patients with some pathology and also users of the Unified Health System. / A atual Política de Saúde Mental no Brasil apóia-se na lei 10.216/02 e busca a consolidação de um modelo de atenção à saúde mental aberto, de base comunitária. Ao incentivar a criação de serviços alternativos ao modelo asilar, torna-se evidente a inclusão da família do usuário dos serviços de saúde mental no tratamento, para proporcionar suporte ao usuário bem como para receber cuidados específicos. Cabe destacar que o cuidado ao portador de transtorno mental pode gerar sobrecarga ao familiar o que pode levar a maior freqüência de problemas relacionados à saúde mental. Estima-se que transtornos relacionados à saúde mental representem 12% da carga global de doenças (OMS, 2001). Este estudo é um subestudo do Projeto CAPSUL. A coleta de dados do subprojeto quantitativo foi realizada em 30 municípios da região sul (Rio Grande do Sul, Santa Catarina e Parana) por 14 duplas de entrevistadores, no período de maio e junho de 2006. Trata-se de um estudo com delineamento transversal com objetivo geral de determinar a prevalência de transtornos psiquiátricos menores e sua associação com variáveis sociodemográficas e sobrecarga em familiares cuidadores de usuários de CAPS no sul do Brasil. O desfecho em estudo são os Transtornos Psiquiátricos Menores, aferidos através da versão brasileira do Self Report Questionnaire (SRQ-20) e as variáveis independentes incluíram características sóciodemográficas, eventos estressores e sobrecarga auto-referida. Entrevistou-se 936 cuidadores. A prevalência de Transtornos Psiquiátricos Menores associou-se com baixa escolaridade, possuir algum problema de saúde, presença de eventos estressores, ser o único cuidador e sobrecarga auto-referida. O estudo contribui para a avaliação da saúde mental dos cuidadores de usuários de CAPS, identificando padrões de ocorrência, fatores associados e grupos mais vulneráveis. Também é útil no delineamento de políticas voltadas aos cuidadores de usuários dos serviços de saúde que apresentam doenças crônicas, incluindo intervenções para promoção da saúde mental, prevenção de riscos e controle dos agravos. Finalmente destaca-se a potencialidade de estudos epidemiológicos abrangentes na avaliação das condições de saúde dos cuidadores familiares de portadores de alguma patologia e também usuários do Sistema Único de Saúde.
24

<i>Pet-1</i> Is Required Across Different Stages of Life to Regulate Serotonergic Function

Liu, Chen January 2010 (has links)
No description available.
25

Patienter med psykisk sjukdom som vårdas inom somatisk respektive psykiatrisk vård: Faktorer av betydelse för vårdpersonal och patienter : – en litteraturöversikt / Patients with psychiatric disorders receiving care within somatic and psychiatric care respectively: factors of importance to healthcare personnel and patients : – a literature review

Ogeryd, Pierre, Cederlöf, Daniel January 2017 (has links)
Bakgrund: Forskning visar att personer med psykisk sjukdom löper ökad risk för fysisk ohälsa men erhåller inte likvärdig vårdkvalité som övriga patientgrupper. Syfte: Litteraturöversiktens syfte var att beskriva faktorer av betydelse för vårdpersonalens upplevelse av att vårda patienter med psykisk sjukdom inom somatisk respektive psykiatrisk vård samt att beskriva faktorer av betydelse för upplevelsen av att som patient med psykisk sjukdom vårdas inom somatisk respektive psykiatrisk vård. Metod: Litteratursökning utfördes i databaserna PubMed, ScienceDirect, Cinahl och PsycInfo. Efter urval utifrån inklusions- och exklusionskriterier samt kvalitetsgranskning återstod 22 artiklar som analyserades genom innehållsanalys. Resultat: Enligt litteraturöversiktens resultat var attityder och fördomar, yrkeserfarenhet, kunskap och kompetens samt arbetsmiljö faktorer av betydelse för upplevelsen av att vårda patienter med psykisk sjukdom inom somatisk vård. Inom psykiatrisk vård var attityder och fördomar, erfarenhet samt kön faktorer av betydelse. Enligt litteraturöversiktens resultat var vårdrelation och personcentrering faktorer av betydelse för upplevelsen av att som patient vårdas inom somatisk vård. Inom psykiatrisk vård var vårdrelation samt självbestämmande och delaktighet faktorer av betydelse. Konklusion: Resultatet talar för att det råder brist på personcentrering inom såväl somatisk som psykiatrisk vård och att personcentrerad vård är en förutsättning för att kravet om god hälsa och vård på lika villkor ska kunna uppnås. / Background: Research shows that individuals with mental illness have an increased risk of somatic diseases, yet won’t receive equal care as other patients. Aim: The aim was to describe factors relevant to nursing staff’s experience of caring for patients with psychiatric disorders within somatic and psychiatric care respectively, and to describe factors of importance for the experiences of patients with psychiatric disorders who receive care within somatic and psychiatric care respectively. Method: Literature search was conducted in PubMed, ScienceDirect, Cinahl and PsycInfo. After a selection using inclusion and exclusion criteras as well as a quality review 22 articles remained which were analysed using content analysis Results: According to the result of the literature review attitudes and prejudice, professional experience, knowledge and competence and work environment were factors relevant to the experience of caring for patients with psychiatric disorders within somatic care. Within psychiatric care attitudes and prejudice, experience and gender were relevant factors. According to the result of the literature review care relation and person-centered care were factors relevant to the experiences of patients with psychiatric disorders receiving treatment within somatic care. Within psychiatric care, care relation and self-determination and involvement were relevant factors. Conclusion: The results indicate a lack of person centered care in both somatic and psychiatric care and that person-centered care is a prerequisite for the achievement of good health on equal terms.
26

Kindliche Traumatisierung, elterliche Erziehungsstile, familiäre Vorbelastung und Geburtsrisikofaktoren bei Patienten mit Schizophrenie / Childhood trauma, parenting skills, psychiatric disorder history and birth risk factors in schizophrenic patients

Auerbach, Isabelle 07 March 2012 (has links)
No description available.
27

Durée de lʼexposition avec symptômes, séquelles et coûts de lʼasthme professionnel en relation avec le statut psychologique et socioéconomique

Miedinger, David 04 1900 (has links)
Le facteur le plus important de pronostic de l'asthme professionnel (AP) est la durée des symptômes avant le retrait de lʼexposition à lʼagent causant lʼAP. La qualité de vie réduite, la détresse psychologique et les maladies psychiatriques sont des conditions souvent associées à l'AP. Notre objectif était d'identifier les facteurs, incluant le statut socioéconomique, qui ont une influence sur lʼintervalle de temps nécessaire pour présenter une requête à une agence médicolégale à la suite de lʼapparition de symptômes dʼasthme et de confirmer qu'un tel délai est associé à un moins bon pronostic respiratoire et à des coûts directs plus élevés. En outre, nous avons examiné la relation entre les variables cliniques et socio-économiques dʼune part et leur influence sur les facteurs psychologiques et économiques dʼautre part chez des travailleurs atteints d'AP. Ensuite, nous avons voulu évaluer si les individus souffrant de détresse psychologique (DP) et de morbidité psychiatrique pourraient être identifiés en utilisant un instrument mesurant la qualité de vie (QV). Lʼétude a été effectuée auprès dʼindividus ayant déposé des demandes d'indemnisation pourʼAP auprès du Commission de la sécurité et de la santé du travail du Québec (CSST). Les données ont été recueillies au moment de la réévaluation, soit environ deux ans et demi après le diagnostic. Outre la collecte des marqueurs cliniques de l'asthme, les individus ont été soumis à une évaluation générale de leur histoire sociodémographique et médicale, à une brève entrevue psychiatrique (évaluation des soins primaires des troubles mentaux, PRIME-MD) et à un ensemble de questionnaires, incluant le Questionnaire sur la qualité de vie - AQLQ(S), le Questionnaire respiratoire de St. George (SGRQ) et le Psychiatric Symptom Index (PSI).Soixante personnes ont été incluses dans l'étude. Etre plus âgé, avoir un revenu supérieur à 30 000$ CA etêtre atteint dʼAP dû à un allergène de haut poids moléculaire ont une association positive avec le nombre dʼannées dʼexposition avec symptômes avant le retrait. Au cours de la période de suivi, le nombre dʼannées dʼexposition avec symptômes était plus grand chez les individus ayant une hyperréactivité bronchique persistante. Par ailleurs, la présence de symptômes au poste de travail pendant moins d'un an est associée à une réduction des coûts directs. Les paramètres de QV et de DP avaient des corrélations modérées avec les marqueurs cliniques de lʼAP. Les plus fortes associations avec ces variables ont pu être observées dans les cas de la sévérité de l'asthme, des statuts dʼemploi et matrimonial, du revenu et de la durée de la période de travail avec l'employeur. Un seuil de 5,1 au niveau de la sous-échelle de la fonction émotionnelle de lʼAQLQ(S) sʼest avéré avoir la meilleure valeur discriminante pour distinguer les individus avec ou sans détresse psychiatrique cliniquement significative selon le PSI. Nous avons été en mesure d'identifier les variables socio-économiques associées à un intervalle plus long dʼexposition professionnelle en présence de symptômes dʼasthme. De même, une plus longue période d'exposition a été associée à un moins bon pronostic de la maladie et à des coûts de compensation plus élevés. Ces résultats s'avèrent utiles pour la surveillance de lʼAP qui pourrait cibler ces sous-groupes d'individus. La QV et la PS sont fréquemment réduites chez les individus atteints d'AP qui perçoivent une compensation. Elles sont associées à des marqueurs cliniques de lʼasthme et à des facteurs socio-économiques. En outre, nos résultats suggèrent que le questionnaire de lʼAQLQ(S) peut être utilisé pour identifier les individus avec un niveau de détresse psychologique potentiellement significatif. / The most important factor in the prognosis of occupational asthma (OA) is the length of exposure with symptoms prior to removal from exposure. Impaired quality of life, psychological distress and psychiatric disease are conditions frequently associated with OA. Our goal was to identify factors, including socio-economic status, that can influence the delay in submitting a claim to a medicolegal agency after the onset of asthmatic symptoms, and to confirm that such a delay is associated with a worse respiratory prognosis and higher direct costs. Further, we examined the association between clinical and socio-economic variables and their influence on psychological and cost outcomes in individuals with OA. Next, we wanted to evaluate whether individuals with clinically significant psychological distress (PD) and psychiatric morbidity could be identified by using a quality of life (QOL) measurement instrument. This is a study of individuals who filed claims for compensation for occupational asthma from the Workersʼ Compensation Board of Quebec (the CSST). Data were collected at re-evaluation, approximately two and a half years after diagnosis. Besides collecting clinical markers of asthma, individuals underwent a general socio-demographic and medical history evaluation, a brief psychiatric interview (Primary Care Evaluation of Mental Disorders, PRIME-MD) and completed a battery of questionnaires, including the Asthma Quality of Life Questionnaire - AQLQ(S), the St. Georgeʼs Respiratory Questionnaire (SGRQ), and the Psychiatric Symptoms Index (PSI). Sixty individuals were included in the study. Being older, having a revenue of >$30,000 Can. (CAD$) and having OA due to high- molecular- weight agents were all positively associated with the number of years of exposure with symptoms before removal from exposure. Individuals with persistent airway hyperresponsiveness at follow-up had a higher number of years with symptoms. Experiencing symptoms in the workplace for less than one year generated lower direct costs. QOL and PD parameters had moderate correlations with clinical markers of OA. Asthma severity, employment and marital status, income and length of employment with the employer showed the strongest associations with QOL and PD. More impaired QOL was associated with higher direct costs for compensation. A cut-off of 5.1 on the AQLQ(S) emotional function subscale had the best discriminative value to distinguish individuals with or without clinically significant psychological distress according to the PSI. We were able to identify socio-economic variables that were associated with a longer interval during which individuals remained symptomatic in the workplace before being removed from exposure. This longer exposure time was associated with worse disease outcomes and higher compensation costs. These findings could prove to be useful in surveillance programs that could be preferentially targeted for these subgroups of individuals. Impaired QOL and PD are frequent among individuals with OA receiving compensation and are associated with clinical markers of OA and socio-economic factors. Further, our findings suggest that the AQLQ(S) questionnaire could be used to identify individuals with potentially clinically significant levels of psychological distress.
28

Durée de lʼexposition avec symptômes, séquelles et coûts de lʼasthme professionnel en relation avec le statut psychologique et socioéconomique

Miedinger, David 04 1900 (has links)
Le facteur le plus important de pronostic de l'asthme professionnel (AP) est la durée des symptômes avant le retrait de lʼexposition à lʼagent causant lʼAP. La qualité de vie réduite, la détresse psychologique et les maladies psychiatriques sont des conditions souvent associées à l'AP. Notre objectif était d'identifier les facteurs, incluant le statut socioéconomique, qui ont une influence sur lʼintervalle de temps nécessaire pour présenter une requête à une agence médicolégale à la suite de lʼapparition de symptômes dʼasthme et de confirmer qu'un tel délai est associé à un moins bon pronostic respiratoire et à des coûts directs plus élevés. En outre, nous avons examiné la relation entre les variables cliniques et socio-économiques dʼune part et leur influence sur les facteurs psychologiques et économiques dʼautre part chez des travailleurs atteints d'AP. Ensuite, nous avons voulu évaluer si les individus souffrant de détresse psychologique (DP) et de morbidité psychiatrique pourraient être identifiés en utilisant un instrument mesurant la qualité de vie (QV). Lʼétude a été effectuée auprès dʼindividus ayant déposé des demandes d'indemnisation pourʼAP auprès du Commission de la sécurité et de la santé du travail du Québec (CSST). Les données ont été recueillies au moment de la réévaluation, soit environ deux ans et demi après le diagnostic. Outre la collecte des marqueurs cliniques de l'asthme, les individus ont été soumis à une évaluation générale de leur histoire sociodémographique et médicale, à une brève entrevue psychiatrique (évaluation des soins primaires des troubles mentaux, PRIME-MD) et à un ensemble de questionnaires, incluant le Questionnaire sur la qualité de vie - AQLQ(S), le Questionnaire respiratoire de St. George (SGRQ) et le Psychiatric Symptom Index (PSI).Soixante personnes ont été incluses dans l'étude. Etre plus âgé, avoir un revenu supérieur à 30 000$ CA etêtre atteint dʼAP dû à un allergène de haut poids moléculaire ont une association positive avec le nombre dʼannées dʼexposition avec symptômes avant le retrait. Au cours de la période de suivi, le nombre dʼannées dʼexposition avec symptômes était plus grand chez les individus ayant une hyperréactivité bronchique persistante. Par ailleurs, la présence de symptômes au poste de travail pendant moins d'un an est associée à une réduction des coûts directs. Les paramètres de QV et de DP avaient des corrélations modérées avec les marqueurs cliniques de lʼAP. Les plus fortes associations avec ces variables ont pu être observées dans les cas de la sévérité de l'asthme, des statuts dʼemploi et matrimonial, du revenu et de la durée de la période de travail avec l'employeur. Un seuil de 5,1 au niveau de la sous-échelle de la fonction émotionnelle de lʼAQLQ(S) sʼest avéré avoir la meilleure valeur discriminante pour distinguer les individus avec ou sans détresse psychiatrique cliniquement significative selon le PSI. Nous avons été en mesure d'identifier les variables socio-économiques associées à un intervalle plus long dʼexposition professionnelle en présence de symptômes dʼasthme. De même, une plus longue période d'exposition a été associée à un moins bon pronostic de la maladie et à des coûts de compensation plus élevés. Ces résultats s'avèrent utiles pour la surveillance de lʼAP qui pourrait cibler ces sous-groupes d'individus. La QV et la PS sont fréquemment réduites chez les individus atteints d'AP qui perçoivent une compensation. Elles sont associées à des marqueurs cliniques de lʼasthme et à des facteurs socio-économiques. En outre, nos résultats suggèrent que le questionnaire de lʼAQLQ(S) peut être utilisé pour identifier les individus avec un niveau de détresse psychologique potentiellement significatif. / The most important factor in the prognosis of occupational asthma (OA) is the length of exposure with symptoms prior to removal from exposure. Impaired quality of life, psychological distress and psychiatric disease are conditions frequently associated with OA. Our goal was to identify factors, including socio-economic status, that can influence the delay in submitting a claim to a medicolegal agency after the onset of asthmatic symptoms, and to confirm that such a delay is associated with a worse respiratory prognosis and higher direct costs. Further, we examined the association between clinical and socio-economic variables and their influence on psychological and cost outcomes in individuals with OA. Next, we wanted to evaluate whether individuals with clinically significant psychological distress (PD) and psychiatric morbidity could be identified by using a quality of life (QOL) measurement instrument. This is a study of individuals who filed claims for compensation for occupational asthma from the Workersʼ Compensation Board of Quebec (the CSST). Data were collected at re-evaluation, approximately two and a half years after diagnosis. Besides collecting clinical markers of asthma, individuals underwent a general socio-demographic and medical history evaluation, a brief psychiatric interview (Primary Care Evaluation of Mental Disorders, PRIME-MD) and completed a battery of questionnaires, including the Asthma Quality of Life Questionnaire - AQLQ(S), the St. Georgeʼs Respiratory Questionnaire (SGRQ), and the Psychiatric Symptoms Index (PSI). Sixty individuals were included in the study. Being older, having a revenue of >$30,000 Can. (CAD$) and having OA due to high- molecular- weight agents were all positively associated with the number of years of exposure with symptoms before removal from exposure. Individuals with persistent airway hyperresponsiveness at follow-up had a higher number of years with symptoms. Experiencing symptoms in the workplace for less than one year generated lower direct costs. QOL and PD parameters had moderate correlations with clinical markers of OA. Asthma severity, employment and marital status, income and length of employment with the employer showed the strongest associations with QOL and PD. More impaired QOL was associated with higher direct costs for compensation. A cut-off of 5.1 on the AQLQ(S) emotional function subscale had the best discriminative value to distinguish individuals with or without clinically significant psychological distress according to the PSI. We were able to identify socio-economic variables that were associated with a longer interval during which individuals remained symptomatic in the workplace before being removed from exposure. This longer exposure time was associated with worse disease outcomes and higher compensation costs. These findings could prove to be useful in surveillance programs that could be preferentially targeted for these subgroups of individuals. Impaired QOL and PD are frequent among individuals with OA receiving compensation and are associated with clinical markers of OA and socio-economic factors. Further, our findings suggest that the AQLQ(S) questionnaire could be used to identify individuals with potentially clinically significant levels of psychological distress.

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