INTRODUÇÃO: A adolescência é uma fase da vida marcada por transformações corpóreas intensas, especialmente nos pés resultando em mudanças no apoio estático e dinâmico. Dentre as metodologias de avaliação desse segmento destaca-se o Índice da Postura do Pé (IPP-6) por ser válido, confiável e multidimensional para verificar possíveis alterações posturais. OBJETIVOS: Caracterizar e relacionar o índice da postura do pé (IPP-6) em adolescentes de acordo com o sexo, faixa etária, índice de massa corpórea (IMC) e lateralidade. MÉTODOS: Foram avaliados 1.400 adolescentes escolares de Amparo e Pedreira em São Paulo, Brasil. Para avaliação eles permaneceram descalços numa base de madeira tendo entre os pés um retângulo de etil vinil acetato (EVA) para padronização da base de apoio. Cada pé foi avaliado pelo IPP- 6 em posição estática, no qual foi classificado entre supinado, normal e pronado através da somatória de seis critérios anatômicos. Cada critério foi graduado entre -2 a +2, sendo que valores negativos indicam supinação, positivos pronação e zero postura neutra. RESULTADOS: Os adolescentes, independentemente do sexo, apresentaram em sua maioria, os pés classificados como normais (lado direito: 78%, esquerdo: 73%). O sexo masculino (0,29, p= 0,04) e o pé esquerdo (0,73, p < 0,001) foram relacionados ao IPP-6, ou seja, em ambas as condições esperam-se que o escore total atribuído a essas variáveis sejam mais elevados (pé direito masculino: 3,09±2,84, esquerdo: 3,76 ± 2,80; pé direito feminino: 2,28 ± 2,61, esquerdo: 3,45±2,66; lateralidade esquerda: 3,55 ± 2,71, direita: 2,82 ± 2,7). Por outro lado, o coeficiente de correlação para o IMC foi negativo (- 0,08, p= < 0,001), o que significa que quanto maior for o IMC menor será o escore atribuído ao IPP-6. CONCLUSÃO: O IPP-6 em adolescentes de 10 a 14 anos está relacionado ao sexo masculino e pé esquerdo, isto é, em ambas as condições o escore predito é maior, logo os pés tendem a se apresentar com maior tendência a pronação. Por outro lado, em relação ao IMC, observa-se uma relação negativa, ou seja, o escore atribuído ao IPP-6 no adolescente classificado com sobrepeso e obesidade é menor. Porém, independentemente do sexo e IMC do adolescente e do pé em que a avaliação seja realizada espera-se que a postura seja classificada como normal / INTRODUCTION: Adolescence is a phase of life marked by intense bodily transformations. This is especially true in the feet, where changes occur in static and dynamic support. Among the evaluation methodologies of this segment, the foot posture index (FPI-6) stands out because it is valid, reliable, and multidimensional to verify possible postural changes. OBJECTIVES: To characterize and relate the FPI-6 in adolescents according to sex, age, body mass index (BMI) and laterality. METHODS: A total of 1,400 schoolchildren from Amparo and Pedreira in São Paulo, Brazil, were evaluated. For evaluation, they remained barefoot on a wooden base, with a rectangle of ethylene- vinyl acetate (EVA) between their feet for standardization of the support base. The FPI-6 was used to evaluate each foot in a static position, in which each foot was classified as either supinated, normal, or pronated after a summation of six anatomical criteria. Each criterion was graded between -2 and +2, with negative values indicating supination, positive values indicating pronation, and zero indicating neutral posture. RESULTS: Adolescents, regardless of their sex had their feet classified as normal (right side: 78%, left side: 73%). The male sex (0.29, p = 0.04) and the left foot (0.73, p < 0.001) were related to the FPI-6--that is, in both conditions, the total score attributed to these variables was higher (male right foot: 3.09 ± 2.84, male left foot: 3.76 ± 2.80; female right foot: 2.28 ± 2.61, female left foot: 3.45 ± 2.66; laterality for left foot: 3.55 ± 2.71, laterality for right foot: 2.82 ± 2.7). On the other hand, the correlation coefficient for the BMI was negative (-0.08, p = < 0.001), which means that the higher the BMI, the lower the score attributed to the FPI-6. CONCLUSION: The FPI-6 in adolescents aged 10 to 14 years is related to the male sex and the left foot--that is, in both conditions, the predicted score is higher, so the feet tend to present with a tendency to pronation. In relation to BMI, however, a negative relation is observed--that is, the score attributed to the FPI-6 in the adolescents who are classified as overweight and obese is lower. However, regardless of the sex and BMI of the adolescent and the foot in which the evaluation is performed, the foot posture is expected to be classified as normal

La profession infirmière en France a vécu des changements récents en termes de recherche et de formation. Dans notre pays, la discipline infirmière est en cours d'institutionnalisation, pourtant il existe déjà des infirmières françaises mettant en ¿uvre des projets de recherche dans une relative autarcie. Dans le contexte actuel professionnel, disciplinaire et intellectuel, comment la recherche infirmière française peut-elle à la fois intégrer la sphère internationale et développer son programme singulier? Il est ambitionné de mettre en lumière ce à quoi les infirmières françaises tiennent, leurs " valeurs " scientifiques. Le programme de recherche Thot, programme séquentiel multi-méthodes, lancé en 2010, étudie le développement de la capacité de recherche infirmière en France. L'étude Thot 1 est une analyse descriptive transversale de l'activité scientifique infirmière à partir du Programme Hospitalier de Recherche Infirmière 2010 et 2011. L'étude Thot 2 est une ethnographie des pratiques de recherche infirmière mises en ¿uvre, combinées à la pratique clinique. Thot 3 est une étude phénoménographique sur les conceptions de la recherche, acquises pendant la formation, par des infirmières titulaires d'un doctorat, en France et en Suède. Les résultats des trois études ont été triangulés au regard de la définition de la science comme pratique socio-culturelle et sept valeurs sont proposées : réflexivité, formation dédiée, cohérence, diversité, confiance, transmission et transformation. Ce programme, déployé et mis en ¿uvre lors d'une des étapes charnières, contribue à l'intégration, dans le futur, des valeurs des infirmières françaises, comme des valeurs scientifiques. / Nursing research and education recently changed in France. In our country, the nursing discipline is currently transforming toward an academic institutionalisation. European development of nursing research is heterogeneous, but the paths of progress seem similar if four sequential stages. Nursing research is characterized by its diversity. However, French nurses implement research projects, in a relative seclusion. In the current professional, disciplinary and intellectual French nursing context, how can nursing research integrate both the international arena and develop its own unique programme? This thesis further aspires to highlight French nurses? scientific values and provide guidelines for nursing research and education in France. The research programme Thot, a multi-method programme, was launched in 2010 to study the development of French nursing research capacity. Thot 1 study was a descriptive cross-sectional analysis of the Hospital Nursing Research Programme 2010 and 2011 scientific activity. Thot 2 study was an ethnography of nursing research practices, combined with clinical practice. Thot 3 was a phenomenographic study of research concepts acquired during a doctoral apprenticeship in France and Sweden. Seven values were derived from the integration of the results of the three studies: reflexivity, dedicated education, coherence, diversity, confidence, transmission and transformation. We hope that this programme, deployed and implemented concurrently to one of the stage of development of nursing in France, will participate in the future integration of the values of French nurses as scientific values,

Objetivo: A hipertensão arterial constitui o principal fator de risco modificável para as doenças cardiovasculares e a maioria dos hipertensos necessitará de medicamento para controlar a pressão. Este estudo analisa a prevalência da hipertensão arterial referida e a utilização de anti-hipertensivos por adultos do município de São Paulo de acordo com variáveis socioeconômicas e demográficas. Métodos: Análise de dados do Inquérito de Saúde no Município de São Paulo – ISA Capital, estudo transversal, de base populacional conduzido em 2003 que possui 1668 adultos com 20 anos ou mais. Para investigar a distribuição das principais classes de anti-hipertensivos, utilização de genérico, forma de obtenção e custeio utilizou-se de um recordatório de três dias. Resultados: A prevalência de hipertensão referida foi de 16,9%, sendo maior nos indivíduos com idade mais avançada, menor escolaridade e sem ocupação. Entre os que referiam hipertensão, a prevalência do consumo de anti-hipertensivo nos três dias que antecederam a entrevista foi de 73,1%. Dos indivíduos que consumiram anti-hipertensivos 38,3% obtiveram o medicamento através do SUS e 35,3% utilizaram genéricos. As principais classes consumidas em monoterapia foram: inibidores da enzima conversora de angiotensina – IECA (41,9%) e diuréticos (24,6%). As principais associações foram: IECA + diurético (36,0%) e diurético + betabloqueador (22,3%). Conclusões: A hipertensão arterial referida se distribui de maneira desigual entre diferentes subgrupos da população. No acesso a medicamento anti-hipertensivo o SUS consegue promover equidade no fornecimento dessas drogas para a população mais desfavorecida. As classes consumidas não estão totalmente de acordo com as diretrizes de hipertensão. / Objective: Hypertension is the major modifiable risk factor for cardiovascular diseases and most of hypertensive patients will require medication for the control of blood pressure. This study analyses the prevalence of self-reported hypertension and the utilization of antihypertensive agents by adults in São Paulo City, Brazil, according to socioeconomic and demographic variables. Methods: Analysis of data from the Health Survey of São Paulo City – ISA Capital, a cross-sectional, population-based survey conducted in 2003 with 1668 adults aged 20 years or over. To investigate the distribution of the main antihypertensive drug classes, utilization of generic drugs and information about how the drugs were obtained, individuals who self-reported hypertension were asked about any drug use for high blood pressure in the previous three days. Results: The prevalence of self-reported hypertension was 16.9%. Advanced age, lower education and not having a job were independently associated with hypertension. The consumption of antihypertensive drugs was 73.1%. Among those who took antihypertensive drugs 38.3% and 35.3%, respectively, obtained the medication from the Brazilian Public Health System (SUS) and used generics. Angiotensin-converting enzyme inhibitors (ACEi) (41.9%) and diuretics (24.6%) were the most used drugs utilized as monotherapy and the most used combinations were ACEi + diuretics (36.0%) and diuretics + beta-blockers (22.3%). Conclusions: The distribution of self-reported hypertension is not equal among different subgroups of the population. The equity in the delivery of antihypertensive drugs is an important component of treatment and control of hypertension and the SUS could perform it to the less advantaged people. The classes consumed do not agree fully with the hypertension guidelines.

Locomotion is one of the most important qualities of man and has always been associated with survival, foraging ans subsistence. During the course of evolution, men and women developed some form of gender specialization which resulted in different level of mobility between the sexes. Throughout history, the types of subsistence have changed and the degree of sedentism has increased. However, despite all the changes in subsistence, gender specialization and bone robusticity sexual dimorphism in the robusticity of the lower limb bones remained surprisingly stable. Is it possible that women load lower limb bones differenty than men (e.i. due to different body proportions)? The aim of this work is to determine wheter there is sexual dimorphism between the sexes of the recent living population in the cross-sectional properties of the tibia and in the load on the tibia during running. In this work we used images of the tibia from magnetic resonance imaging and kinematic and kinetic data during the run of 20 probands. By using musculoskeletal modeling we estimated the bending moment acting at 50 % of the tibial length as well as the angle of action of this moment. After adjusting for size, no significant difference was found in the results of cross-sectional geometry of the bone in any of the monitored...

Il a été postulé qu’en plus d’influencer les comportements parentaux, les caractéristiques personnelles des parents joueraient un rôle important dans leur degré de coopération avec leur partenaire (Abidin, 1992 ; Belsky, 1984). Toutefois, peu d’études se sont penchées sur les liens unissant les traits de personnalité des parents et l’alliance parentale (Jacobson et al., 1995; Stright et Bales, 2003). Le premier objectif de l’étude était donc d’évaluer les liens intra-parents, c’est-à-dire si les traits de personnalité d’un parent d’enfant d’âge préscolaire permettent de prédire sa propre perception de l’alliance parentale et ce, après avoir contrôlé pour l’effet de son niveau de scolarité, de son revenu ainsi que de sa perception de sa situation financière. Le second objectif était d’examiner les liens inter-parents, donc de vérifier si les traits de personnalité d’un partenaire contribuent à prédire la perception de l’alliance parentale de l’autre parent. Finalement, le troisième objectif consistait à vérifier s’il existait des différences sexuelles dans les relations prédictives entre les traits de personnalité et l’alliance parentale. L’échantillon est composé de 170 dyades de parents ayant un enfant âgé entre 42 et 48 mois et résidant dans la grande région métropolitaine de Montréal. Les parents ont été évalués par le biais de questionnaires auto-révélés. Les résultats montrent que l’amabilité des mères et la stabilité émotionnelle des pères sont positivement associées à leur perception de l’alliance parentale. De plus, une forte amabilité chez les conjoints prédit positivement l’alliance parentale, autant pour les mères que les pères. Par ailleurs, le trait d’amabilité maternelle prédit significativement mieux la perception de l’alliance parentale des pères que l’amabilité paternelle. Toutefois, aucune différence sexuelle significative n’a été constatée quant à la magnitude de la contribution des traits de personnalité des parents sur la perception de l’alliance parentale des mères. Cette étude met en lumière l’importance de certaines caractéristiques personnelles influençant la perception de la coopération entre les parents sur la sphère parentale. / It has been theorized that personality has implications in both parenting behaviours and the extent to which parents are willing to collaborate in order to respond to a child’s changing needs (Abidin, 1992 ; Belsky, 1984 ). However, few studies examined the relationship between parent’s personality traits and their parenting alliance (Jacobson et al., 1995; Stright et Bales, 2003). This study focused on three objectives. The first aim was to examine the influence of parent’s personality traits on his own perception of the parenting alliance. The second objective was to verify if the partner’s personality traits predicted the perception of the parenting alliance of the other parent. Lastly, the study aimed to identify potential sexual differences in the predictive relations between personality traits and parenting alliance. Data was collected using a sample of 170 mothers and fathers of children aged 24 to 48 months, living in the Montreal area, who completed self-report questionnaires. The results of this study show that high agreeableness in mothers and high emotional stability in fathers were linked to better perception of the parenting alliance. Furthermore, spouse’s high agreeableness predicted higher parenting alliance scores, for both parents. Compared to father’s agreeableness, mother’s agreeableness is significantly a better predictor of father’s perception of the parenting alliance. Also, when mother’s and father’s scores were compared, none of the partner’s personality traits emerged as a more significant predictor of the parenting alliance as perceived by mothers. This study provides evidence that some parent’s characteristics are important in understanding how they perceive the cooperation with their spouse in regard to parenting.

There are many large-scale contacting methods for gas reactions requiring a solid catalyst. The catalytic gas-solid Fluidized Bed Reactor (FBR) is one of the popular methods in industry. In FBRs the bulk of the gas throughput is present as lean bubbles, mostly deprived of solids, bubbling through a solids-rich emulsion phase. The movement of gas into and out of the emulsion often dictates the performance of an FBR. During the past five decades major contributions have been made towards the understanding of FBRs, although numerous gaps still exist, especially at higher bubbling regime velocities. This work follows an integrated approach for the simultaneous measurement of hydrodynamics and reactor performance. Hydrodynamics are measured using fast X-Ray Tomography (XRT), pressure analysis techniques and an optical fibre probe. Reactor performance is measured by utilizing the ozone decomposition reaction. Performance is quantified using a basic two-phase reactor model with an apparent overall interphase mass transfer (K0) parameter. Two 14 cm (ID) fluidized bed columns are used, one setup supporting the ozone decomposition reaction and the other installed within a fast XRT facility. Special emphasis is placed on superficial velocities (U0) spanning the entire bubbling regime up to the onset of the turbulent regime (Uc). The particle types employed are Geldart B sand particles and highly dense ferro-silicon (FeSi) particles. Fines are added to both particle types, resulting in a total of four particle systems (sand baseline; sand with fines; FeSi baseline; FeSi with fines). Time constraints on the XRT equipment limited the tomography measurements to the sand baseline particle system. The hydrodynamics of the other particle systems were limited to the pressure signal and optical probe measurements of the ozone decomposition setup. The results of the sand baseline system suggest that a distinction should be made between the low-interaction bubbling regime and the high-interaction bubbling regime. A change in mass transfer behaviour occurs around a U0/Uc value of 0.25. Reactor performance increases up to U0/Uc = 0.7, after which a decreasing trend is observed. An empirical correlation is proposed for the specific interphase mass transfer (kbe) of the higher velocity bubbling regime. This correlation is based on the integration of the hydrodynamics determined by means of XRT and reactor performance: 4-12 The hydrodynamic parameter β gives the best fit for the entire velocity range with an average error of 8%, although it is not recommended for U0/Uc<0.17. It is observed that the classical approach of penetration theory for interphase mass transfer, performs exceptionally well at low velocities (U0/Uc<0.34). The addition of fines to the FeSi particle type decreases the overall reactor performance, despite decreased bubble sizes. The solids fraction, however, unexpectedly increases with the addition of fines and a collapse of the emulsion phase is measured. It is therefore postulated that though flow in the emulsion phase is much higher for the FeSi baseline system and decreases with the addition of fines. For the sand particle type, the behaviour expected from literature is observed: reactor performance increases, bubble sizes decrease and the solids fraction decreases. Very distinct hydrodynamic behaviour is observed for all the fluidization regimes with XRT. Probability density distributions show there are still two phases present in the turbulent regime and that the emulsion-phase solids fraction remains independent of velocity until fast fluidization sets in. The turbulent regime has unique hydrodynamic behaviour, although voids appear to be a transient structure between the structures of the bubbling and fast fluidization regimes. / Thesis (PhD)--University of Pretoria, 2013. / gm2014 / Chemical Engineering / unrestricted

Context: The facial subunit principle organizes the facial skin into subunits. Facial reconstruction for skin cancer based on aesthetic units consists of replacing the entire subunit when a large part of a subunit has been removed. Aims: To determine the prevalence of facial skin cancer, their location by facial aesthetic units, and the type of facial reconstruction used in each of them. Settings and Design: An observational cross-sectional study was conducted at the Head and Neck Surgery Service of a general hospital between 2017 and 2018. Materials and Methods: A population census was conducted during this period. Statistical Analysis Used: The categorical variables were expressed as frequencies (percentages). Continuous variables were described as the means and standard deviations or medians and interquartile ranges. Results: The most common skin cancer was basal cell skin cancer, followed by epithelial skin cancer and, at last, melanoma. In general, the most frequent localization of these cancers was the nose. Conclusions: In spite of primary closure being the most common form of reconstruction, a considerable number of patients required facial reconstruction based on aesthetic facial units, with satisfying results. / Revisión por pares

With the growing popularity of business analytics, companies experience an increasing need of reliable data. Although the availability of behavioural data showing what the consumers do has increased, the access to data showing consumer mentality, what the con- sumers actually think, remain heavily dependent on tracking surveys. This thesis inves- tigates the performance of a Dynamic Factor Model using respondent-level data gathered through repeated cross-sectional surveys. Through Monte Carlo simulations, the model was shown to improve the accuracy of brand tracking estimates by double digit percent- ages, or equivalently reducing the required amount of data by more than a factor 2, while maintaining the same level of accuracy. Furthermore, the study showed clear indications that even greater performance benefits are possible.

Bakgrund: Att barn drabbas av hjärtstopp är ovanligt men tyvärr är överlevnadsgraden låg. Träning och repetition inom hjärt- och lungräddning är nödvändig för att sjuksköterskor ska kunna bevara sin kompetens och klara av att utföra HLR med bra kvalitet. Trots att det finns riktlinjer och rekommendationer för barn-HLR är tidsspannet mellan utbildningstillfällena längre än rekommenderat. Motiv: Eftersom HLR på barn sällan behöver utföras och det finns brister i kontinuiteten av den praktiska och teoretiska utbildningen skapas svårigheter för sjuksköterskor att upprätthålla sina kunskaper. Forskning kring hur sjuksköterskors självskattar sin kompetens inom barn-HLR är mycket bristfällig. Syfte: Syftet med studien var att undersöka sjuksköterskors självskattade kompetens att utföra barn-HLR, samt att mäta sambandet mellan den självskattade kompetensen och antalet yrkesår och tid sedan senaste HLR-utbildningen. Metod: Datainsamlingen genomfördes med hjälp av ett självrapporteringsformulär via en webbaserad enkät med sjuksköterskor (n=55) som rekryterades via ett icke slumpmässigt urval. Resultat: Sjuksköterskorna skattade sin kompetens inom larmrutiner, luftvägshantering, kompressionsteknik och sin övergripande kompetens inom HLR som hög. Svaga skillnader hittades hos de som självskattat sin kompetens till hög respektive låg, där de som arbetat längre även skattade sin kompetens som högre. Konklusion: Det är kanske inte utbildningen i sig som påverkar den självskattade kompetensen inom barn-HLR utan sjuksköterskans kliniska erfarenhet. En hög självskattad kompetens inom barn-HLR ger inga garantier för ett korrekt utförande och eftersom behovet av mer utbildning och simulering var högt kan det finnas en osäkerhet gällande kunskap och utförandet bland sjuksköterskorna. Att främja sjuksköterskors kompetensutveckling inom verksamheten kan bidra till en ökad kunskap och ett mer korrekt utförande av barn-HLR och därmed ge det drabbade barnet en högre chans till överlevnad. / Background: The fact that children suffer from cardiac arrest is unusual, but unfortunately the survival rate is low. Training and repetition in cardiopulmonary resuscitation is necessary for nurses to be able to maintain their competence and be able to perform CPR with good quality. Although there are guidelines and recommendations for pediatric CPR, the time span between training sessions is longer than recommended. Motive: As CPR on children rarely needs to be performed and there are shortcomings in the continuity of the practical and theoretical training, difficulties are created for nurses to maintain their knowledge. Research on how nurses' self-assess their competence in pediatric CPR is very deficient. Aim: The purpose of the studies was to investigate nurses' self-assessed competence to perform pediatric CPR, and to measure the relationship between the self-assessed competence and the number of professional years and time since the most recent CPR training. Methods: The data collection was carried out using a self-report form via a web-based questionnaire with nurses (n = 55) which was recruited via a non-random sample. Result: The nurses rated their competence in alarm routines, airway management, compression technology and their overall competence in CPR as high. Weak differences were found among those who self-assessed their skills to high and low, respectively, where those who worked longer also rated their skills as higher. Conclusion: It may not be the education itself that affects the self-assessed competence in pediatric CPR but the nurse's clinical experience. A high self-rated competence in pediatric CPR provides no guarantees for a correct execution and since the need for more training and simulation was high, there may be an uncertainty regarding knowledge and execution among the nurses. Promoting nurses' competence development within the business can contribute to increased knowledge and a more correct execution of pediatric CPR and thus give the affected child a higher chance of survival.

Introduction: Coronavirus 2019 (SARS-CoV-2) infection in children occurred in Peru as of March 2020, leading to pediatric patients' hospitalization in areas adapted for this purpose at the Edgardo Rebagliati Martins National Hospital. In the beginning, the demand for hospitalization was low, but it increased gradually. Consistent with international reports, the majority of patients presented mild or moderate symptoms. Nonetheless, there were also severe cases, even fatal ones. Objectives: To describe the characteristics and clinical outcome of pediatric patients with COVID-19 hospitalized in a referral hospital in Lima, Peru, between March and August 2020. Methods: A descriptive and inferential cross-sectional study was carried out. The population includes all hospitalized patients in the Department of Pediatrics, with clinical and surgical diagnoses associated with COVID-19. Results: We included 100 patients, with an average age of 83.4 ± 54 months, with a predominance of male patients (55%). Hospitalized patients were grouped into five categories: respiratory failure (17%), multisystemic inflammatory syndrome (MIS-C) (31%), neurological presentation (19%), acute abdomen (20%), and patients with oncological problems (13%). Most of the patients (74%) had comorbidities. Regarding the presenting symptoms, intestinal pain predominated in the appendicitis group (90%, p < 0.001), fever was present in most patients with respiratory failure (64.7%); multisystemic inflammatory syndrome (90.3%), neurological manifestations (15.8%), acute abdomen (50%) and oncological conditions (61.5%) were also present in these patients. Kawasaki symptoms were found in 38.7% of the patients with multisystemic inflammatory syndrome. Mortality was 4%. Respiratory problems (29.4%) and multisystemic inflammatory syndrome (22.6%) required admission to intensive care, more frequently than the other presentations (p = 0.008). Conclusions: We conclude that the vulnerability in the pediatric population is the one that has preexisting conditions. We divided our patients according to presentation, diagnosis, and complications, which were predominantly respiratory. We also had oncological patients with COVID-19. / Introducción: La infección por coronavirus 2019 (SARS-CoV-2) en niños se presentó en Perú desde marzo del 2020. Desde entonces fue necesario internar pacientes pediátricos en el Hospital Nacional Edgardo Rebagliati Martins, en el área de hospitalización adaptada para dicho propósito. Al inicio, la demanda de hospitalización era baja y se fue incrementando progresivamente. Coincidiendo con los reportes internacionales, la mayoría presentó cuadros leves o moderados, pero también hubo casos graves e incluso mortales. Objetivos: Describir las características y el desenlace clínico de los pacientes pediátricos con COVID-19 hospitalizados en un hospital de referencia en Lima, Perú, entre marzo y agosto de 2020. Métodos: Se realizó un estudio transversal descriptivo e inferencial. La población incluyó a todos los pacientes que se hospitalizaron en el Departamento de Pediatría Clínica, con diagnósticos clínicos y quirúrgicos asociados a COVID-19. Resultados: Incluimos 100 pacientes, con edad promedio de 83,4 ± 54 meses, con predominio de varones (55%). Los pacientes hospitalizados fueron agrupados en cinco categorías: insuficiencia respiratoria (17%), síndrome inflamatorio multisistémico (31%), presentación neurológica (19%), abdomen agudo (20%) y pacientes con problemas oncológicos (13%). La mayoría de los pacientes (74%) tenían comorbilidades. Respecto a los síntomas de presentación, el dolor intestinal predominó en el grupo de apendicitis (90%, p < 0,001), la fiebre estuvo presente en la mayoría de los pacientes con falla respiratoria (64,7%), el síndrome inflamatorio multisistémico se registró en 90,3%, la sintomatología neurológica en 15,8%, el abdomen agudo 50% y oncológicos en 61,5% de los pacientes. Los síntomas de Kawasaki estuvieron presentes en 38,7% de los pacientes con síndrome inflamatorio multisistémico. La mortalidad fue de 4%. En 29,4% de problemas respiratorios y en 22,6% de síndrome inflamatorio multisistémico, se requirió de admisión en cuidados intensivos, lo que fue más frecuente que las otras presentaciones (p = 0,008). Conclusiones: Se concluye que la población pediátrica vulnerable es aquella con comorbilidades preexistentes. La división de pacientes en nuestro estudio fue definida por la presentación, diagnóstico y complicaciones predominantemente con problemas respiratorios, y en pacientes oncológicos con COVID-19. / Revisión por pares