Background The point of departure in this thesis is that unemployment is a recognised determinant of health, which may vary between different ages and among men and women. Despite governmental policies to tackle unemployment and ease its effects on health, unemployment continues to bea growing public health problem. Aim The objective of the thesis was to analyse, from a gender perspective, the relationships between ill health and unemployment as well as other unstable labour market positions in the transition from youth to adulthood. The aim of each paper was: I. Does the association between ill health and unemployment differ between young people and adults? II. Is the transition from an unstable labour market position to permanent paid job health-protective? III. Is participation in labour market programmes related to mental health? IV. What is the association between ill health among men and women and how could it be analysed with a relational theory of gender? Methods The longitudinal study was carried out in Luleå - a medium-sized industrial town in the Northern Sweden. The cohort, consisting of all 1083 pupils (506 girls and 577 boys) aged 16 who attended the last year of compulsory school in 1981, was followed up at the ages of 16, 18, 21 and 30. The response rates were high e.g. 96.4% at 14 years follow-up. The cohort was followed with extensive and well-validated questionnaires. Multivariate logistic regression was used in all papers, while propensity score matchingwas used in Paper III. Results Paper I. Health effects of long-term unemployment differed between young people and adults. Long-term unemployment was more related to psychological ill health and smoking in young people than in adults. Paper II. The results indicated that after controlling for gender as well as for an indicator of health-related selection, possible confounders and mediators transition from an unstable labour market position to permanent employment could be health-promoting. Paper III. No association was found between participation in active labour market programmes and psychological symptoms. Due to methodological shortages the results have to be interpreted with caution. Adjustment for either all background selection variables or the propensity score in multivariate logistic regression showed similar associations suggesting that propensity score could be used to adjust for background selection variables. Paper IV. A strong association between unemployment and suboptimal self-rated health among women and high alcohol consumption among men was found and a theory of structural relations was used to discuss the gendered patterns for ill health. Conclusion The thesis indicated gendered patterns of relations between unemployment and the health outcomes, in the transition from youth to adulthood. The policy implications of my thesis are that full employment policies should be promoted to reduce the health inequalities associated with unemployment. / The Northern Swedish Cohort study

This thesis focused on factors contributing to improved work environment in small-scale enterprises and sustainable health for the entrepreneurs. In Study I, implementation of the provision of Systematic Work Environment Management (SWEM) with and without support was investigated. Two implementation methods were used, supervised and network method. The effect of the project reached the employees faster in the enterprises with the supervised method. In general, the work environment improved in all enterprises. However, extensive support to small-scale enterprises in terms of advice and networking aimed at fulfilling SWEM regulations had limited effect – especially considering the cost of applying these methods. Studies II, III, and IV focused on entrepreneurs’ health, work conditions, strategies for maintaining good health, and utilisation of Occupational Health Service (OHS). A closed cohort of entrepreneurs in ten different trades responded to two self-administered questionnaires on health and work conditions, with five years between the surveys: at baseline, 496 entrepreneurs responded, and 251 entrepreneurs responded at follow-up. Differences were tested by Chi2-test, and associations estimated with logistic regression analyses. Qualitative interviews on entrepreneurs’ strategies for maintaining good health were included. In Study II, the most frequently reported complaints, musculoskeletal pain and mental health problems, were associated with poor job satisfaction and poor physical work environment. In Study III, consistent self-reported good health, i.e. good health both at baseline and at follow up, was associated with self-valued good social life when adjusted for physical work conditions and job satisfaction. Entrepreneurs’ strategies for maintaining good health included good planning and control over work, flexibility at work, good social contact with family, friends and other entrepreneurs, and regular physical exercise. Study IV concerned entrepreneur’s utilisation of OHS. Entrepreneurs affiliated to OHS had either better or more adverse work conditions than non-affiliated entrepreneurs. Medical care and health check-ups were the services most utilised. Affiliation to OHS correlated with use of specific information sources and active work environment management. The entrepreneurs were not consistently affiliated to OHS over the five-year-period.

Background: The main objective of this study was to investigate older people’s physical activity, their participation in various life situations, and their perceptions of their own health. This included an exploration of potential influences of urban versus rural residency on these outcomes, an evaluation of the measurement properties of a balance confidence scale, and an examination of the proposed usefulness of the International Classification of Functioning, Disability and Health (ICF) as a conceptual framework to facilitate analysis and understanding of selected outcomes. Methods: The study design was cross-sectional, population-based, with random selection from the national register of one urban and two rural municipalities in Northern Iceland. There were 186 participants, all community-dwelling, aged 65 to 88 years (mean = 73.8), and 48% of the group were women. The participation rate was 79%. Data was collected in 2004, in face-to-face interviews and through various standardized assessments. The main outcomes were total physical activity; leisure-time, household, and work-related physical activity; participation frequency and perceived participation restrictions; and self-rated health. Other assessments represented aspects of the ICF body functions, activities, environmental factors and personal factors. Moreover, Rasch analysis methods were applied to examine and modify the Activities-specific Balance Confidence (ABC) scale and the ICF used as a conceptual framework throughout the study. Results: The total physical activity score was the same for urban and rural people and the largest proportion of the total physical activity behavior was derived from the household domain. Rural females received the highest scores of all in household physical activity and rural males were more physically active than the others in the work-related domain. However, leisure-time physical activity was more common in urban than rural communities. A physically active lifestyle, urban living, a higher level of cognition, younger age, and fewer depressive symptoms were all associated with more frequent participation. Rural living and depressive symptoms were associated with perceived participation restrictions. Moreover, perceived participation restrictions were associated with not being employed and limitations in advanced lower extremity capacity. Both fewer depressive symptoms and advanced lower extremity capacity also increased the likelihood of better self-rated health, as did capacity in upper extremities, older age, and household physical activity. Rasch rating scale analysis indicated a need to modify the ABC to improve its psychometric properties. The modified ABC was then used to measure balance confidence which, however, was found not to play a major role in explaining participation or self-rated health. Finally, the ICF was useful as a conceptual framework for mapping various components of functioning and health and to facilitate analyses of their relationships. Conclusions: The results highlighted the commonalities and differences in factors associated with participation frequency, perceived participation restrictions, and self-rated health in old age. Some of these factors, such as advanced lower extremity capacity, depressive symptoms, and physical activity pattern should be of particular interest for geriatric physical therapy due to their potential for interventions. While the associations between depressive symptoms, participation, and self-rated health are well known, research is needed on the effects of advanced lower extremity capacity on participation and self-rated health in old age. The environment (urban versus rural) also presented itself as an important contextual variable to be aware of when working with older people’s participation and physically active life-style. Greater emphasis should be placed on using Rasch measurement methods for improving the availability of quality scientific measures to evaluate various aspects of functioning and health among older adults. Finally, a coordinated implementation of a conceptual framework such as ICF may further advance interdisciplinary and international studies on aging, functioning, and health.

En viktig faktor för människans förmåga att arbeta är hälsa. På arbetsplatsen tillbringar människan mer än en tredje del av sina liv, vilket gör arbetsplatsen till en betydande arena i skapandet av hälsa. Kommuner har som arbetsgivare i Sverige generellt en sämre hälsa samt högre sjukfrånvaro bland sina anställda än andra arbetsgivare. De som jobbar inom vård och omsorg har generellt dåliga psykosociala arbetsförhållanden. Den psykosociala arbetsmiljön i form av höga krav, bristande kontroll och dåligt socialt stöd kan påverka hälsan negativt, vilket kan öka rörligheten på arbetsmarknaden i form av att fler tenderar att byta jobb på grund av dåliga arbetsförhållanden. Syftet är att undersöka samband mellan självskattad psykosocial arbetsmiljö, självskattad hälsa och övervägandet att byta jobb bland kommunanställda inom äldre- och handikappomsorgen i Sverige. Studien har genomförts som en deduktiv tvärsnittsstudie och är en del av en störres studie.  Den baseras på 9 270 kommunanställda inom äldre- och handikappomsorgen i Sverige. Studien teoretiska referensram är krav/kontroll/stöd modellen. Analys skedde genom univariata, bivariata och multivariata metoder.    Resultatet visar att det fanns signifikanta bi- och multivariata samband mellan att kommunanställda som upplever den psykosociala arbetsmiljön som god även skattar hälsan bättre samt i mindre utsträckning överväger att byta jobb än de som upplever sämre psykosocial arbetsmiljö. Ålder och antal år på arbetsplatsen hade betydelse för övervägandet att byta jobb. Detta i form av att ju äldre de anställda är samt ju längre de arbetat på arbetsplatsen desto mindre är övervägandet att byta jobb. Slutsatsen är att den psykosociala arbetsmiljön hade betydelse för den upplevda hälsan och övervägandet att byta jobb bland kommunanställda inom äldre och handikappsomsorgen. / Health is an important prerequisite for the ability to work. In the workplace, the human being spends more than a third of their lives. This makes the workplace a major arena for health promotion. Municipalities have as employers in Sweden generally poorer health and higher rates of sick leaves among the employees than other employers. Those who work in health care have bad demanding working conditions. Psychosocial work environment in the form of high demands, lack of control and poor social support may affect health negatively. This can increase labor market mobility in the form of more tend to change jobs due to poor working conditions. The aim of this study is to investigate the relationship between self-rated psychosocial work environment, self-rated health and occupational mobility among municipal employees in the elderly and disabled care in Sweden. The study is implemented as a deductive cross sectional study and is a part of a major study. It is based on a sample of 9 270 municipal employees in the elderly and disabled care in Sweden. The theoretical frame of reference of study is the demand / control / support model. The analyses were done by univariat, bivariat - and multivariate methods. The results show that there were significant correlation between municipal employees who experience the psychosocial work environment as good rated health better and lesser extent considering changing jobs than those who experience poorer psychosocial work environment. Age and number of years in the workplace was relevant to the consideration of changing jobs. This is in the form of the older employees are and the longer they worked in the workplace, the less is the consideration of changing jobs. The conclusion is that the psychosocial work environment was important for the perceived health and the consideration to change jobs among municipal employees in the elderly and disabled.

Diss. (sammanfattning) Umeå : Umeå universitet, 2009. / Härtill 4 uppsatser. Även tryckt utgåva.

Tyrimo tikslas – nustatyti kaip susiję paauglių prieraišumo prie tėvų stilius su interneto naudojimo intensyvumu bei subjektyviu sveikatos vertinimu. Tyrime dalyvavo 142 mokiniai (108 merginos ir 34 vaikinai), 96 mokiniai anketas pildė internetu, 46 Viešojoje įstaigoje Kauno „Vyturio“ katalikiškoje vidurinėje mokykloje. Tiriamieji pildė anketą, kurią sudarė keturios metodikos, prieraišumo stiliaus, žmonės mano gyvenime, subjektyvaus sveikatos vertinimo ir interneto naudojimo intensyvumo klausimynas. Tyrimo rezultatai parodė, kad prieraišumas prie tėvų, subjektyvus sveikatos vertinimas ir interneto naudojimo intensyvumas skiriasi atskirose sociodemografinėse grupėse: vaikinai savo sveikatą vertina geriau nei merginos, paaugliams; gyvenantiems su abiem tėvais, būdingas didesnis prieraišumas prie tėvų ir geresnis subjektyvus sveikatos vertinimas, nei gyvenantiems su vienu iš tėvų; teigiantys, jog nejaučia skausmų, savo sveikatą vertina geriau ir ne taip intensyviai naudoja internetą, nei tiriamieji, pažymėję, jog jaučia skausmus; pildžiusių anketas mokykloje subjektyvus sveikatos vertinimas geresnis, nei pildžiusių anketas internetu. Paauglių subjektyvus sveikatos vertinimas reikšmingai koreliuoja su prieraišumu prie tėvų, gautas ryšys silpnas. Aukštas, žemas paauglių subjektyvus sveikatos vertinimas skirtingose sociodemografinėse grupėse statistiškai reikšmingai skiriasi išskyrus paauglių gyvenančių su vienu iš tėvų. Paaugliams, kuriems būdingas vyraujantis nerimastingo... [toliau žr. visą tekstą] / The aim of the study was to assess connections between adolescent attachment to parents‘ style with intensity of internet use and self – rated health. The subjects of the study were 142 students (108 girls and 34 boys), 96 students questionnaires were filled out online, 46 studets questionnaires filled out in the Catholic secondary school. Students were asked to fill 4 questionnaires: Relationship Scale Questionnaire, People In My Life, Internet Addiction Test and subjective helth questionnaire. The results of the study showed that attachment to parent, self – rated health and intensity of internet use are different among sociodemographical groups: boys evaluate their health better than the girls. Adolescent who lived with their parent have more attachment to parent and their health is better, comparing with adolescent who lived with one of his parent. Adolescent who wrote that do not feel pain their health are better and they use less intensity of the internet than students, who wrote, that feel pain. Students who filled questionnaire in school have better health than students who filled questionnaire online. Adolescents‘self – rated health was correlated with attachment to parent. Anxious attached subjects have had lower health than save attached subject. Save attached subjects are more attached to parent. Anxious attached subjects are more intensity of internet use.

Obesity and physical inactivity are major risk factors for numerous chronic diseases, conditions, and early mortality. Healthy body weight and physical activity (PA) are also positively associated with health-related quality of life (HRQL). However, obesity and physical inactivity levels in Canadian youth and adults are high. This thesis comprises five studies exploring the burden of obesity and physical inactivity, focusing on HRQL. The first study assessed PA research productivity in Canada from 1990-2005. Canada produced approximately 5% of global PA research, 50% originating from Ontario, the biomedical and clinical areas accounting for 40% each; however, research in population health and health services was lacking. The second study used data from the Physical Activity Longitudinal Study (PALS), the 22-year follow-up of the 1981 Canada Fitness Survey, to assess PA and obesity tracking from youth to adulthood. Over 80% of overweight/obese youth became overweight/obese adults, while the majority of overweight/obese adults had not been overweight/obese youth; almost all healthy weight adults had been healthy weight youth. PA did not track over 22 years. The third study used the PALS data to examine the long-term effect of youth BMI and PA on adult HRQL (SF-36), using dichotomized outcomes based on Canadian norms. Contrary to expectations, overweight youth were more likely than healthy weight youth to score at/above the norm in adult HRQL, especially in the mental health domains. Youth PA was not associated with adult HRQL. The fourth study used the same data to explore the youth BMI-adult HRQL relationship using continuous outcomes, by sex. Youth BMI was positively associated with mental HRQL in adult females only; no negative impacts emerged. The fifth study used the Canadian Community Health Survey (CCHS) Cycle 3.1 data to investigate the combined association of PA and BMI to HRQL among Canadian adults, including self-rated health, participation/activity limitation, and total disability days, by age and sex. Inactive individuals had increased odds of adverse HRQL, regardless of weight status; underweight, overweight, and obesity were of little consequence for active individuals. Collectively, these results help to better understand the health burdens created by the current epidemics of obesity and physical inactivity in Canadians throughout their lifespans. / Thesis (Ph.D, Kinesiology & Health Studies) -- Queen's University, 2010-12-08 18:00:44.214

The growing prevalence of childhood and adolescent physical inactivity and obesity are major concerns in Canada. Physical activity promoted within schools should be seen as a way to address these problems, since the majority of children receive public schooling. Research highlighting in-school physical activity helps influence school board and public health officials to create a physically active school environment. Consequently, this study has two objectives. The first is to describe the prevalence of in-school physical activity and four dependent variables in a nationwide sample of 9717 students, using data from the Health Behavior in School–aged Children survey. Dependent variables include life satisfaction, self-rated health, academic performance, and out-of-school physical activity. The second objective examines the association between in-school physical activity levels and these dependent variables, while controlling for potential confounders. Using existing data from the 2005/06 Health Behaviour in School-aged Children Survey, a partial proportional odds model form of ordinal logistic regression was fitted in order to investigate the relationship between in-school physical activity and self-rated health, life satisfaction, academic performance, and out-of-school physical activity, while controlling for potential confounders. The results showed a significant positive relationship between in-school physical activity and life satisfaction (OR range: 1.18 – 1.50), in-school physical activity and self-rated health (OR range: 1.10 – 2.86), in-school physical activity and academic performance (OR range: 1.20 – 1.40), and in-school physical activity and out-of-school physical activity (OR range: 1.09 - 6.68). Consequently, it is recommended that school environments which encourage physical activity continue to be promoted, and future studies continue to explore the benefits of in-school physical activity. / Thesis (Master, Community Health & Epidemiology) -- Queen's University, 2011-01-21 10:42:29.807

Background  Occupation-focused and occupation-based interventions can potentially promote occupational engagement among community-dwelling older people, but there is limited evidence to identify the most effective and cost-effective interventions. For independent-living older people, there is a lack of evidence to determine if occupation-focused and occupation-based interventions have an effect on their occupational engagement. For older people who need assistance because of bathing disabilities, there is limited evidence of the effects of occupation-focused and occupation-based interventions on their occupational engagement or for reducing or omitting their need for assistance. Finally, there is limited evidence to determine if occupation-focused and occupation-based interventions implemented for community-dwelling older people are cost effective. Aim The aim of this thesis was to evaluate the effects and cost effectiveness of occupation-focused and occupation-based interventions for two groups of community-dwelling older people, independent-living, community-dwelling older people and older people with bathing disabilities. Method Studies I and II were based on an exploratory randomized controlled trial. One hundred and seventy seven persons, 77–82 years, single living, and without need for home help were randomized to a no-intervention control group or to one of three occupational therapy interventions focused on promoting occupational engagement: an individual intervention, an activity group or a discussion group. In study I, effect sizes for leisure engagement and ability to perform activities of daily living (ADL) tasks were estimated for each intervention in relation to the control group to identify the most effective intervention at 3 and 12 months after baseline. In study II, the effects on quality adjusted life years (QALYs) and the total costs for the intervention, social services provided by the municipality and health care were used evaluate cost-effectiveness. Study III was a quasi-experimental clinical trial and included 95 persons, 65+, who had applied for municipality-based home help with bathing. For participants in the intervention group, occupational therapists implemented occupation-focused and occupation-based interventions. No occupational therapy intervention was implemented for those in the control group, but they were allocated home help services if judged to need it based on an assessment by a municipality care manager. Evaluations of ADL ability, self-rated health and allocated home help were implemented at baseline and after 15 weeks. Study IV involved the use of decision-modeling based on a five state Markov model that included levels of dependency in ADLs, place of residency and death. Probabilities for transitions between states in the model, QoL scores and societal costs for each state were derived from previous research. Overall, the model was based on research indicating that more severe levels of dependency reduced QALY scores and increased societal costs. Previous trials have provided evidence that an occupation-focused and occupation-based intervention implemented to reduce bathing disabilities increased the probability of independence of home help. The Markov model was used to evaluate cost-effectiveness over 8 years for an intervention compared to no intervention. Results The results of study I indicated that each intervention had a small positive effect on minimizing a decline in leisure engagement and/or ADL, but no intervention was clearly superior. In study II, the results indicated that the interventions delivered in a group format positively affected self-rated health. The discussion group was the most cost-effective intervention. The results of study III indicated that the intervention had no effect on ADL ability or self-rated health. There was, however, a large difference in the allocation of home help at follow up, indicating that the intervention was effective in reducing dependency on home help for bathing. The results of study IV indicated that compared to no intervention, the intervention resulted in a positive accumulation of QALYs and lower costs for every year during the entire 8 year period. Conclusion This thesis provides evidence to support the implementation of occupation-focused and occupation-based interventions for independent-living, community-dwelling older people in order to reduce their decline in occupational engagement and improve their self-rated health; the interventions also have the potential to be cost effective. This thesis also provides evidence that an occupation-focused and occupation-based intervention implemented for older people with bathing disabilities was effective in promoting independence from home help for bathing. Finally, an occupation-focused and occupation-based intervention that increased the probability of being independent of home help for bathing had a positive impact on the long term accumulation of QALYs and reduced societal costs and, therefore, can be considered very cost effective.

Background and aim: As an experienced paediatric nurse I have recognised that adolescents with persistent chronic childhood diseases fall between two chairs. International studies support this recognition. Norwegian adolescents with juvenile idiopathic arthritis are no exception. Chronic arthritis from childhood might have far-reaching consequences for the growth and development of the child, and for the family and community. The fact that a considerable proportion of children with JIA continue to have active disease and disease residua through adolescence into adulthood underlines the importance of illuminating the situation in a public-health perspective. Through this study I aim at exploring physical and psychosocial health among young adults with JIA in a life-span perspective from childhood and adolescence into adult life. Methods: The thesis has a qualitative and a quantitative approach. Study I had an abductive explorative design. The experiences and perceptions of health-care transition were explored by focus-group interviews with young people with JIA and related health professionals respectively. Qualitative content analysis was utilised. Study II had an abductive explorative design with qualitative interviews to explore young adults’ experiences of living with JIA in a life-span perspective. Qualitative content analysis was utilised. Study III had a longitudinal deductive design. The standardised questionnaires of Health Assessment Questionnaire, General Health Questionnaire version 30, and Visual Analogue Scales of pain, fatigue, and illness were utilised to explore physical ability, psychosocial health, pain, fatigue, and illness in a cohort of patients with JIA 18.3 years after symptom-onset. Comparisons with baseline and first follow-up were performed. Data were analysed by descriptive statistics and non parametric tests. Study IV had a cross-sectional deductive design. In addition to the questionnaires utilised in study III, the questionnaire of SF-36 Health Survey and data on education, employment, need of assistive equipment at work, and use of health services the previous year were employed. Comparisons with Norwegian population- based data were performed. Data were analysed by descriptive statistics, and parametric and non parametric tests. Findings: In study I, ability to live a meaningful and responsible adult life seemed to be a common goal. Obstacles for the young people were the nature of the disease, a lack of focus on transition processes, and overprotective parents and health professionals. Obstacles for the health professionals were lack of inter-professional and inter-institutional formal co-operation and agreed practice, and lack of competence on adolescent development and health. Study II demonstrates that living with JIA implies a constant oscillation between struggle and adjustment to an insecure everyday life and an unpredictable life course. This was expressed as bodily experiences of limitation and freedom, interpersonal experiences of being included or set on the sidelines, and intrapersonal perceptions of insecurity and confidence. Of the 55 young adults with JIA in study III, 21 reported physical disability, and 12 reported psychiatric distress within the clinical range. Furthermore, 26 patients reported illness, 27 pain, and 33 fatigue above 10 on the VAS scale (0-100). Significant correlations were found between physical disability, pain, illness and fatigue, and between psychiatric distress, pain, and fatigue. Comparisons from first to second follow-up of the cohort showed no significant changes in physical or psychosocial functioning, pain, or fatigue. In study IV, physical ability and pain were significant predictors of the average variation of physical health while psychiatric distress and female gender were significant predictors of the average variation of mental health. Impaired physical health was associated with low rates of psychiatric distress. As compared to the general Norwegian population, impaired HRQL in the physical domain was found, but not in the mental domain, and a higher level of education, but similar employment rate. Conclusion: The four studies demonstrate complementary findings. Discrepancies between interviews and inquiries indicate that the interviews illuminate a depth and breadth of life with JIA in a life-span perspective that not is possible to unveil solely by standardised inquiries. Although persistent favourable outcomes are found physically and psychosocially from first to second follow-up, young adults with JIA reveal that life with JIA encompasses struggle and adjustment to an insecure life situation physically, psychologically, and socially. / Bakgrunn og mål: Mange års erfaring som pediatrisk sykepleier har vist meg at unge mennesker med kroniske barnesykdommer faller mellom to stoler i overgangen til voksent liv. Internasjonale studier støtter denne erfaringen, og norske ungdommer med juvenil idiopatisk artritt er ikke noe unntak. Kronisk barneleddgikt kan ha vidtrekkende konsekvenser for barnets vekst og utvikling, for familien og samfunnet for øvrig. Det faktum at mange barn fortsetter å ha aktiv sykdom og senvirkninger av sykdommen gjennom ungdomsårene og inn i voksent liv, understreker betydningen av å belyse de unges helse og livssituasjon i et folkehelseperspektiv. Gjennom denne avhandlingen ønsker jeg å undersøke fysisk, psykisk og sosial helse blant unge voksne med barneleddgikt i et livsløpsperspektiv. Metode: Avhandlingen har en kvantitativ og en kvalitativ tilnærming. Studie I hadde en abduktiv eksplorerende design. Gjennom fokusgruppeintervjuer med respektivt unge mennesker med barneleddgikt og helsepersonell innen revmatologi ble opplevelser og erfaringer med overgangen til voksenhelsetjenesten undersøkt. Kvalitativ innholdsanalyse ble benyttet. Studie II hadde også en abduktiv eksplorerende design med kvalitative intervjuer for å utforske livet med barneleddgikt blant unge voksne i et livsløpsperspektiv. Kvalitativ innholdsanalyse ble benyttet også her. Studie III hadde en longitudinell deduktiv design. Standardiserte spørreskjemaer om fysisk funksjon (Health Assessment Questionnaire), psykososial helse (General Health Questionnaire versjon 30), og sykdomsfølelse, smerte og trøtthet (Visual Analogue Scales) ble anvendt for å undersøke selvvurdert helse blant kohorten 18.3 år etter symptomdebut. Sammenligning med baselinestudien og første oppfølging ble gjort. Deskriptiv statistikk og non parametriske tester ble benyttet i dataanalysen. Studie IV var en deduktiv tverrsnittsstudie. I tillegg til spørreskjemaene som ble benyttet i studie III, ble spørreskjemaet SF-36 Health Survey benyttet for å undersøke selvvurdert helserelatert livskvalitet. Data fra telefonintervjuet om utdanning, yrkesaktivitet, behov for hjelpemidler på jobb, og behov for helsetjenester siste året ble inkludert. Sammenligninger ble gjort med norske normdata. Deskriptiv statistikk, parametriske og non parametriske tester ble benyttet i dataanalysen. Funn: Studie I viste at det å være i stand til å leve et meningsfylt og ansvarsbevisst voksenliv var et felles mål. Hindringer for de unge viste seg å være sykdommens natur, manglende fokus på overgangsprosessen, og overbeskyttende foreldre og helsepersonell. Hindringer blant helsepersonell var mangel på formelt samarbeid og omforent praksis på tvers av profesjoner og institusjoner, og mangel på kompetanse om ungdoms helse og utvikling. Studie II viste at livet med barneleddgikt innebærer en konstant veksling mellom kamp og tilpasning til et usikkert dagligliv og et uforutsigbart livsløp. Dette kom til uttrykk i erfaringer om kroppslige begrensninger eller frihet, interpersonlige opplevelser av å bli inkludert eller satt til side, og intrapersonlige opplevelser av usikkerhet eller trygghet. Blant de 55 unge voksne med barneleddgikt i studie III rapporterte 21 fysiske funksjonshemninger og 12 psykiatrisk distress. Videre rapporterte 26 pasienter sykdomsfølelse, 27 smerter, og 33 trøtthet med en skåring på 10 eller mer på VAS-skalaene (0-100). Signifikante korrelasjoner ble funnet mellom fysisk funksjonshemning, smerter, sykdomsfølelse og trøtthet, og mellom psykiatrisk distress, smerter og trøtthet. Sammenligninger fra første til andre oppfølging av kohorten viste ingen signifikante endringer i fysisk eller psykisk funksjonsevne, smerter eller trøtthet. Studie IV viste at fysisk funksjons-hemning og smerter var signifikante prediktorer for den gjennomsnittlige variasjonen i fysisk helse, mens psykiatrisk distress og kvinnelig kjønn var signifikante prediktorer for den gjennomsnittlige variasjonen i mental helse. Sviktende fysisk helse var ikke assosiert med psykiatrisk distress. Sammenlignet med norske normdata fant vi sviktende helserelatert livskvalitet i det fysiske domene, men ikke i det mentale domene, og høyere utdanningsnivå, men ingen forskjell i yrkesaktivitet. Konklusjon: Funnene fra de fire delstudiene kompletterer hverandre. Diskrepansen mellom funnene fra intervjuene og spørreskjemaene belyser en bredde og dybde i opplevelsene avlivet med barneleddgikt som det ikke er mulig å avdekke bare gjennom bruk av standardiserte spørreskjemaer. Selv om funnene viser vedvarende positive utfall av sykdommen både fysisk og psykososialt fra første til andre oppfølging, viser unge mennesker med barneleddgikt at livet innebærer kamp og tilpasning til en usikker livssituasjon fysisk, psykisk og sosialt.