Thesis (M.G.S.)--Miami University, Dept. of Sociology and Gerontology, 2006. / Title from first page of PDF document. Includes bibliographical references (p. 31-32).

Made available in DSpace on 2015-07-22T20:50:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-11-25. Added 1 bitstream(s) on 2015-08-11T03:25:34Z : No. of bitstreams: 1 Publico-020a.pdf: 165301 bytes, checksum: 478022db64b034bbea30c204bbaf2cb9 (MD5). Added 1 bitstream(s) on 2015-08-11T03:25:34Z : No. of bitstreams: 2 Publico-020a.pdf: 165301 bytes, checksum: 478022db64b034bbea30c204bbaf2cb9 (MD5) Publico-020b.pdf: 118674 bytes, checksum: 3222abfa356d637cdb4ac8248c91cf7a (MD5). Added 1 bitstream(s) on 2015-08-11T03:25:35Z : No. of bitstreams: 3 Publico-020a.pdf: 165301 bytes, checksum: 478022db64b034bbea30c204bbaf2cb9 (MD5) Publico-020b.pdf: 118674 bytes, checksum: 3222abfa356d637cdb4ac8248c91cf7a (MD5) Publico-020c.pdf: 2073396 bytes, checksum: 04ba8e01c6f7b4dd2421e5babffdd4b9 (MD5) / Um número desconhecido de pacientes com câncer experimenta reações e interações de drogas graves, podendo resultar em hospitalização e até em morte. Particularmente, pacientes portadores de neoplasia maligna comumente recebem um grande número de medicamentos, além de receberem drogas com alto risco de efeitos adversos. Desta forma, dois estudos foram realizados como base para esta tese: uma revisão sistemática e em estudo retrospectivo. A revisão sistemática da literatura avaliou os estudos publicados sobre a epidemiologia de interações medicamentosas em pacientes com câncer. A busca identificou 8 estudos: 7 artigos publicados no PubMed e um resumo publicado nos proceedings do congresso da sociedade americana de oncologia (ASCO). A maioria dos estudos era retrospectiva e avaliou potenciais interações medicamentosas, com apenas dois estudos publicados sobre reais interações medicamentosas. Aparentemente, um terço dos pacientes oncológico ambulatoriais recebe combinações de drogas com risco de interação. Os principais fatores de risco para interações medicamentosas são: idade avançada, número crescente de medicações, presença de lesões cerebrais (primárias ou secundárias) e pacientes que recebem drogas consideradas de risco como anticonvulsivantes, varfarina e anti-inflamatórios hormonais e não-hormonais. O segundo estudo desta tese avaliou a prevalência de potenciais interações medicamentosas entre pacientes com câncer terminal. Desta forma, nós revisamos retrospectivamente os prontuários de todos os pacientes com câncer que foram atendidos no ambulatório de Cuidados Paliativos, do Hospital Princess Margaret, Toronto, Canadá, num período de 8 meses. As listas de medicações foram rastreadas para interações pelo programa eletrônico Drug Interaction Facts, que classifica as interações por nível de gravidade (maior, moderada e menor) e evidência científica (1 a 5, onde 1 = maior nível de evidência). Dentre os 372 pacientes avaliados, 250 interações medicamentosas potenciais foram identificadas em 115 pacientes (31%, 95% Intervalo de Confiança 26 - 36%), predominantemente envolvendo varfarina e fenitoína. A maioria das potenciais interações foi classificada como de gravidade moderada (59%) e 41,5% possuíam níveis de evidência 1-3. Na análise multivariada, idade crescente (p<0,001), pelo menos uma comorbidade (p=0,001), tipo de câncer (tumores cerebrais, p<0,001) e número crescente de medicamentos utilizados (p<0,001) foram associados a risco de interações medicamentosas. Portanto, concluiu-se que potenciais interações medicamentosas são comuns entre pacientes oncológicos que estejam recebendo cuidados de suporte exclusivos, sendo que a maioria envolve varfarina e/ou anticonvulsivantes. Fatores de risco incluem idade avançada, pacientes com múltiplas comorbidades, tumores cerebrais e aqueles que utilizam muitas medicações. / Background: Drug-drug interactions (DDIs) comprise an important problem in medical oncology practice. We systematically reviewed the frequency of DDIs in oncology. Methods: We searched PubMed for eligible articles and online databases abstracts of major oncology meetings. Results: Eight studies reported on the frequency of DDIs: six evaluated the frequency of potential DDIs while 2 studies reported on real DDIs, i.e. interactions that had clinical consequences. Studies of potential DDIs found that approximately one third of patients are exposed to dangerous drug doublets, with the most common ones involving warfarin and anticonvulsants. One study of real DDIs found that 2% of hospitalized cancer patients had a DDI as the cause of admission. Conclusion: Drug interactions comprise an important issue in oncology, with approximately one third of ambulatory cancer patients being at risk of DDIs. Data are limited on the clinical consequences of drug interactions among cancer patients. / TEDE / BV UNIFESP: Teses e dissertações

CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior / O objetivo desta tese à compreender como, no Conjunto Palmeiras, um bairro situado na periferia de Fortaleza, construiu-se, ao longo do tempo, a imagem de um bairro solidÃrio. Entende-se que tal imagem resultou tanto da mobilizaÃÃo em torno das demandas sociais para o bairro como do desenvolvimento de experiÃncias consideradas inovadoras no campo da economia solidÃria que o tornaram conhecido e reconhecido internacionalmente, sobretudo ao final da dÃcada de 1990, alvo de inÃmeros estudos acadÃmicos, detentor de visibilidade midiÃtica e premiaÃÃes. Em meados de 2000, tais iniciativas expandiram-se como polÃtica de governo, por meio da Secretaria Nacional de Economia SolidÃria (SENAES). O ponto central, desta forma, à entender de que modo essas iniciativas ditas solidÃrias foram sendo difundidas e adquiriram legitimidade perante o Estado e a sociedade civil e quais as implicaÃÃes desse processo que une duas lÃgicas aparentemente contraditÃrias. Para tanto, orientada por uma perspectiva metodolÃgica qualitativa, a tese teve como foco as seguintes questÃes: que atores sociais participam do processo de construÃÃo dessa imagem? De que maneira atuam? Qual a extensÃo das iniciativas ditas solidÃrias? Que percepÃÃo de solidariedade perpassa as relaÃÃes de parcerias firmadas entre os atores sociais envolvidos? Quais implicaÃÃes tendem a ocorrer com a institucionalizaÃÃo dessas iniciativas diante do carÃter solidÃrio que originalmente as particularizaram? Conclui-se que, atualmente, as iniciativas solidÃrias no Conjunto Palmeiras desenvolvem-se, do ponto de vista institucional, em um campo ainda nÃo definido. Se por um lado, buscam-se instrumentos cabÃveis à sua autonomia legal, por outro, ao se institucionalizarem tais experiÃncias, abre-se o caminho para que outros referenciais passem a demarcar estas iniciativas, provavelmente distintas daqueles que a embasaram em sua gÃnese. / The aim of this thesis is to understand how the neighbourhood Conjunto Palmeiras, located in the suburbs of Fortaleza, has built throughout time the image of a supportive neighbourhood. It is understood that this image is the result of movements related to social demands, such as the development of experiences considered to be innovative in the field of the supportive economy. Those movements, therefore, made Conjunto Palmeiras a target of an uncountable amount of academic studies, many of them awarded, which turned it into an internationally known and acknowledged neighbourhood, especially in the late 90âs. In the mid-2000s, those initiatives have been expanded as a Government policy by the National Secretary of Supportive Economy - SENAES (Brazilian initials). Hence, the main point of this work is to understand which ways those initiatives were widespread and gained legitimacy before the State and the civil society as well as which are the implications of this process, that connects two apparently contradictory rationales. Therefore, guided by a qualitative methodological perspective, the thesis focuses on: Who are the social actors who take part in the process of building this image? How do they work? What is the extent of the so-called supportive initiatives? What perceptions of solidarity permeate the correlation of partnership between the social actors involved? Which implications tend to occur with the institutionalisation of those initiatives before the supportive character that originally particularised? As a result, we conclude that, currently, Conjunto Palmeirasâs supportive initiatives, from an institutional point of view, develop themselves into a field not yet specified. If on one hand, it is sought applicable instruments to its legal autonomy, on the other hand, by institutionalising such experiences, a new path is open in order to allow other references to demarcate those initiatives, probably different from those ones in its genesis.

Många ungdomar med olika typer av problem kan i dagsläget inte bo kvar hemma. Anledningarna till det kan ligga hos ungdomen själv eller hos ungdomens familj och närsamhälle och kan då placeras på ett stödboende. Studiens syfte är att undersöka om ungdomar på stödboendet Kollektivboendet (Kollbo) i Örebro upplever sig vara delaktiga i den stödjande verksamheten och hur delaktigheten ser ut. Studien är en kvalitativ undersökning baserad på sex semistrukturerade intervjuer med ungdomar boende på Kollbo och i deras slusslägenheter. De sex pojkarna är slumpmässigt utvalda utifrån ett antal sammanställda kriterier. Resultatet av studien framställs under olika teman som vi har identifierat under intervjuerna. Resultatet visade på att majoriteten av ungdomarna till stor del upplever sig delaktiga i den stödjande processen på Kollbo. Det framkommer även att ungdomarna är positiva till personalen och Kollbo, men att det finns vissa aspekter där pojkarna upplever att delaktigheten brister. / Many young people with different types of problems can at present not live at home. The reasons to it can lie at the youth alone or at the youth’s family and near society and can then be placed on a supportive residential home. The study's purpose is to examine whether young people on Kollektivboendet (Kollbo) in Örebro are to be involved in supporting activities and how the participation looks. The study is a qualitative survey, based on six semi structured interviews with young people living at the supportive residential home Kollbo and in their sluice-gate apartments. The six boys are randomly selected from a number of consolidated criteria. The results of the study are produced under different themes that we have identified during the interviews. The results showed that the majority of young people largely feel involved in the supporting process around themselves at Kollbo. It is found that young people feel positive towards the staff and Kollbo, but that there are certain aspects where the boys experiences that the participation deficiencies.

This diploma thesis deals with learning styles and their effectiveness amongst pupils with specific learning disabilities. The theoretical part describes the problems of specific learning disorders, the current legislation and the possibilities of care for pupils with specific learning disabilities in school counseling facility, learning styles, learning habits amongst pupils with specific learning disorders and basic diagnostics of learning styles. The practical part is focused on the research and includes quantitative research which focuses on revealing the predominant style of learning at the second level of elementary school amongst pupils with learning disabilities and its comparison with the regular population of pupils. The thesis also answers a range of questions, such as, what helps learners who have learning disabilities to make the most out of their work, what disturbs the learners during learning, and compares these findings with pupils without any learning disabilities. The results of the survey revealed that pupils with specific learning disabilities involved in the research are predominant in the auditory style of learning. There were no differences found between predominant learning styles in pupils with learning disabilities and pupils without these disorders.

Women treated for a gynecological cancer report longstanding post-treatment difficulties for which they rarely seek or receive help. Few intervention studies have successfully improved global sexual health within this population. Research in this domain is challenging due to inconsistent measurements of sexuality, low response rates and high attrition rates. The overarching study objectives were: (a) To contribute to the advancement of research on supportive care needs (including sexual health needs), desire for help, and predictors of needs; and, (b) To inform the development of services for gynecological cancer survivors. In Study 1, a qualitative interview study explored the experiences of 15 gynecological cancer survivors. Interviews were conducted and analysed based on the Interpretive Description approach . In Study 2 (for which results were analyzed in two parts), a descriptive, cross-sectional needs assessment was conducted to measure supportive care needs, desire for help, sexual health and vaginal changes, and service format preferences in 113 patients. In Part 1 of Study 2, descriptive and regression analyses explored patient needs, desire for help and potential predictors of these variables. In Part 2, a descriptive analysis explored sexual health needs and vaginal changes, desire for help with sexual health needs, and their associations with sociodemographic and medical variables. Qualitative results from Study 1 suggested that psychological, emotional and relational aspects of sexuality were as important to the participants as physiological sexual response. In the needs assessment, the strongest predictors of greater unmet needs and increased readiness for help were younger age and shorter time since treatment. Moderate to high sexual and social needs were equally prevalent in women recently treated and those treated several years prior to the study, suggesting that sexual and social needs may remain unaddressed over time. Further, many women who reported a need did not desire help, demonstrating the subjectivity of needs and distress, as well as the potential presence of barriers to seeking help. Both studies revealed a common finding, where sexual health needs were a product of the discordance between participants’ current sexual experiences and their perceptions of ideal sexual health. Overall, the two studies indicate that a significant subgroup of patients experience unmet needs in cancer survivorship, most of which are non-physical; also, while some needs were higher following treatment, unmet social and sexual health needs show little relationship with time since treatment. Ambivalence about receiving help with unmet needs is related to beliefs about the role of the health care team in meeting non-physical needs, as well as other perceived barriers. Patient’s perceived sexual health needs and barriers to receiving help should be evaluated within a comprehensive framework of needs and discussed one-on-one. Future research should explore the added predictive value of other groups of medical and psychological variables.

No description available.

Among the goals of recent supported work employment programs is improvement of competitive employment opportunities for individuals who suffer from chronic mental illness, and for whom competitive employment outcomes are poor. This study examined the effects of a vocational rehabilitation program, Project Success (Skills Upgrade: Client Centered Empowerment Supportive Services), on self esteem and quality of life for chronically mentally ill participants.

Boundaries in the growth of women entrepreneurship, in general, are for example family responsibility, gender discrimination, missing networks and the lack of interaction with other successful entrepreneurs. This is especially critical in developing countries where the women have to face additionally barriers. The existence of supportive organizations is crucial in creating opportunities for female entrepreneurship. One example of a female entrepreneurial network that supports women doing business is GSWIM (Grooming a Successful Woman with an Intellectual Mind), operating in Kampala, Uganda. This thesis will study the knowledge sharing behaviour within the organization. The main data collection has been retrieved through interviews held with five business women, members of GSWIM. A developed version of the MOA framework (Motivation, Opportunity, Ability) have been used to analyse the collected data. It is shown that there are a lot of things in GSWIM that facilitate the knowledge sharing behaviour. GSWIM motivate, inspire and are proficient in communicating the value of sharing knowledge. However, there are some crucial aspects for improvements related to increased ability, belongingness of members and decentralization. The long-term orientation is along with team cohesiveness, probably two of the network’s major assets. By providing a network for women, and a platform for knowledge sharing, GSWIM has reduced some barriers to entrepreneurship in Uganda.

Philosophiae Doctor - PhD / In concluding this dissertation I am reminded of Patton's (1990) contention that in order to decide what the appropriate unit of analysis is in a study, you need to decide what it is you want to be able to say something about at the end of the study. The unit of analysis of this study was the characteristics of and strategies for developing a successful school. At the end of this study, in relation to the South African education context, I wanted to say something about what a successful school looks like and, with special reference to school OD, how a school can become successful by examining Modderdam's success story (the case) in relation to TIP's school OD model (the intervention), international and local research on successful schools (the literature), and' current South African education policies and reform initiatives (national education reform). I was particularly concerned with saying something about the implications of this study for education reform in South Africa and, where possible, other contexts. These intentions were based on the two broad aims of this study which were: The nature of this study was illuminative and not scientifically absolute. Based on the principle of learning from success it endeavoured to deepen our understanding of what constitutes a successful school and how a school can become successful. The particular context is the South African education reform process. As such, it aimed to provoke insights rather than definitive answers in response to the aims of this study. The insights that have been generated by this study have manifested at different levels of 'depth'. Chapter eight discussed emerging insights which ranged from findings such as the striking similarity between the case study's successes and the twelve generic characteristics of a successful school based on the literature, to the contention that, unlike schools in a developed context, a school in the South African context cannot be the primary unit of change. Chapter nine consolidated these emerging insights into three key insights which have in some respects gone beyond the aims of this study by, for example, proposing a framework of core conditions for an enabling school level environment. In summarising this study's insights I have attempted to portray the iterative nature of propositional order. In accordance with its two broad aims, the table below summarises this study's main insights and the implications of these insights for education reform in South Africa and beyond. the analysis process by starting with those which are of a more basic, 'findings' level and finishing with those which are of a more deeper,