Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro / O processo de educação em saúde é um dos determinantes para a qualidade da atuação das equipes de atenção básica. A educação permanente, em especial, possibilita o aprendizado dinâmico a partir das demandas do cotidiano do trabalhador. Atualmente, a educação a distância é um dos meios pelos quais os profissionais podem se aprimorar, rompendo com incompatibilidades temporais e geográficas. Com este objetivo, foi instituído em 2007, pelo Ministério da Saúde, o Programa Telessaúde Brasil, que visa a educação permanente a distância dos profissionais da estratégia de saúde da família, sendo o Rio de Janeiro um dos núcleos do projeto piloto. Esta pesquisa teve como objetivos: a) Identificar e caracterizar, do ponto de vista sócio-demográfico, acadêmico e quanto ao uso de tecnologias de internet, os enfermeiros inseridos no Projeto Telessaúde Brasil núcleo Rio de Janeiro, segundo as regiões fluminenses; b) Identificar, categorizar e analisar as principais demandas de educação permanente apontadas pelos enfermeiros participantes no momento da adesão; c) Descrever e analisar a participação dos enfermeiros em atividades específicas. O Projeto possui duas atividades básicas: a teleconferência, funcionando de modo síncrono, em que o profissional tem a oportunidade de participar de aulas sobre temas de interesse com possibilidade de interação; e, a segunda opinião formativa que, de modo assíncrono possibilita ao trabalhador obter a opinião de um especialista sobre qualquer dúvida de seu cotidiano. A metodologia utilizada foi quantitativa, com desenho longitudinal e observacional, delineamento de pesquisa não experimental e caráter descritivo. Os dados foram obtidos entre os anos de 2009 e 2010 utilizando três fontes: formulários de Linha de base, registro de teleconferências e registros de perguntas e respostas de segunda opinião formativa. Os resultados indicam que o perfil do profissional fluminense é composto por trabalhadores do sexo feminino, jovens de formação recente, especialistas e com conhecimentos básicos sobre tecnologias de informação e comunicação. Verificou-se também que a maior parte das dúvidas do enfermeiro da ESF ainda é pautada em dúvidas clínicas, seguidos de dúvidas sobre implementação de atividades em educação permanente. Conclui-se pela viabilidade e importância deste tipo de atividade de educação permanente, em que pesem algumas contradições e dificuldades para o enfermeiro da atenção básica, que constituem-se em desafios a serem superados. / The education process is a determinant factor for the quality of service of health professionals. Permanent Education, particulary, enables dynamic learning from the daily demands of the professional. Currently, distance education is one means by which practitioners can improve, surpassing temporal and geographical incompatibilities. In this sense, it was established in 2007 by the Ministry of Health the Brazil Telehealth Program, which seeks to promote permanent distance education for professionals involved in the family health strategy, being Rio de Janeiro as one of the cores of the pilot project. This research aimed to: a) Identify and characterize, in terms of socio-demographic, academic, and on the use of Internet technologies, the nurses inserted into Telehealth Project Brazil Rio de Janeiro Nucleus, Rio de Janeiro according to region, b) To identify, categorize and analyze the permanent education demands pointed by the participants, c) Describe and analyze the participation of nurses in specific activities. The Project has two basic activities: the teleconference, working synchronously in wich the professional has the opportunity of attending classes about subjects there ar in accordance with the interaction possibility and, the second formative opinion, asynchronously working, giving the worker the possibility to obtain the opinion of an expert on any doubt in his everyday life. The methodology was based on a quantitative approach with longitudinal design and observational, not experimental research design and descriptive character. Data were collected between the years 2009 and 2010 and analyzed according to three sources of information: Baseline forms, teleconferences and formative second opinions. The results indicate that the professional profile of Rio de Janeiro is composed of female workers, young, recently trained, specialists and with basic knowledge on information technologies and communication. It was also found that most of the questions are still related to clinical issues, followed by questions about implementation of activities on continuing education. The conclusion shows the feasibility and importance of this type of continuing education activity, in spite of some contradictions and difficulties for nurses in primary care, which are challenges to be overcome.

Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-03-23T14:05:40Z No. of bitstreams: 1 doradeisestephanmoreira.pdf: 1242070 bytes, checksum: 1472da6e12332e2c2680116e16da0c2a (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-04-24T02:31:14Z (GMT) No. of bitstreams: 1 doradeisestephanmoreira.pdf: 1242070 bytes, checksum: 1472da6e12332e2c2680116e16da0c2a (MD5) / Made available in DSpace on 2016-04-24T02:31:14Z (GMT). No. of bitstreams: 1 doradeisestephanmoreira.pdf: 1242070 bytes, checksum: 1472da6e12332e2c2680116e16da0c2a (MD5) Previous issue date: 2013-03-08 / O presente trabalho versa sobre as transformações por que passaram a relação do homem com o sagrado, desde os primórdios até os dias atuais. Na pré-história essa relação se dava, essencialmente, de forma a garantir a sobrevivência dos hominídeos, diante das intempéries da natureza. Num estágio mais avançado, houve uma intensificação dessa relação, uma vez que o homem das sociedades arcaicas passou a atribuir um sentido sagrado a tudo que estava ao seu redor, através das hierofanias. Veneravam-se deuses por intermédio de totens, extraídos do próprio meio ambiente. Com o advento das religiões de salvação, que tiveram no Cristianismo seu maior expoente, surgiu o elemento mediador entre o homem e o sagrado, representado, sobretudo, pelos profetas e sacerdotes. Por um longo tempo, as identidades religiosas possuíram um caráter mais fixo e permanente. Gradativamente, foi dando-se o processo de secularização da sociedade, fator que, dentre outros, ocasionou mudanças substanciais no campo religioso, impactando sobremaneira essas identidades. Os arautos do sagrado foram se transmutando. Com o aumento populacional, para se chegar até os fiéis tornou-se necessário o trabalho de mediadores mais portentosos: os veículos de comunicação. O foco de nossa pesquisa é a mediação televisiva e o peso que ela exerce na formação identitária religiosa na contemporaneidade. Deter-nos-emos na análise dos programas televangélicos, os quais representam anualmente cerca de cinco mil horas da programação dos canais abertos, conforme dados do OBITEL – Observatório Ibero-Americano da Ficção Televisiva. Nesse vasto universo, escolhemos como recorte empírico os programas Fala Que Eu Te Escuto (IURD/Rede Record) e Direção Espiritual (Igreja Católica/TV Canção Nova). Para interpretá-los, utilizamos princípios da Análise de Conteúdo, metodologia que tradicionalmente, desde a sua primeira aplicação, vem possibilitando a análise verticalizada de mensagens religiosas. / This paper deals with the changes that have come to man's relationship with the sacred, since the early days to the present. In prehistory this relationship occurred essentially to ensure the survival of the hominids in front the storms of nature. At a later stage, there was an intensification of this relationship, and the man of archaic societies began to assign a sacred meaning to everything that was around him, through hierophanies. Gods are worshiped through totems, taken from the environment itself. With the advent of religions of salvation, which had its greatest exponent in Christianity, arose the mediating element between man and the sacred represented mainly by the prophets and priests. For a long time, religious identities owned a character more fixed and permanent. Gradually occurred the process of secularization of society, a factor that, among others, led to substantial changes in the religious field, impacting greatly those identities. The heralds of the sacred were transmuting itself. With the increase of population, to reach to the faithful, became necessary the work of a more portentous mediator: the media. The focus of our research is the mediation televised and the weight it carries in the contemporary religious identity formation. We will consider in the analysis of tele-evangelicals programs, which represent annually about five thousand hours of open channels programming, according to the Obitel - Ibero-American Observatory of Fiction Television. In this vast universe, we have chosen as empirical cut the programs Fala que eu te escuto (IURD/ Rede Record) and Direção Espiritual (Catholic Church / TV Canção Nova). To dissect them we have used the principles of the Content Analysis, a methodology that traditionally, since its first application, is making possible a detailed analysis of religious messages.

Near field communication (Nfc), a contact-range and short-lived message exchange technology, has in recent years become popular in relation to payment-cards, key-cards and ski-passes. With the release of, in particular, the Google Nexus S, which is capable of reading and writing Nfc tags as well as exchanging messages between devices by touch, the roles of consumers have changed from carriers of passive cards to that of active readers. This publicly available hardware technology, embedded into relatively cheap connected smartphones, creates a new field of possibilities in which a complete and complex Nfc-based system can be developed solely by means of software. In this thesis work, the research is in relation to the field of Nfc, ranging from the physical characteristics of the technology to the design of the Nfc API on the Android platform. Nfc-based apps, library and systems are designed, developed and evaluated in terms of performance. The Android apps which are implemented are WiFi and Bluetooth connectors as well as an Nfc-sensor value visualizer. Additionally, two full systems are developed which consists of an Android app, backend server, database and web or PC-client frontend. These two systems are: a web-based high-performance live statistical visualizer of Nfc sensor values and an Nfc-scan based product endorsement, Like-event, presenting the picture and name of a user endorsing a product on the in-store advertisement displays on top of the ads. The system for scanning, distributing and presenting statistics on sensor-values from a specially crafted NfcV-enabled sensor is evaluated in terms of performance along the chain of events starting at the Nfc tag introduction and being dispatched on the mobile phone and ending with the calculations and plot-generation carried out by the browser connected to the backend via a WebSocket. The evaluations show that in a use-case in which the user holds a tablet in one hand and an Nfc-enabled smartphone in the other, the user would experience a mean-delay of 515 milliseconds between putting the device against an NfcV-sensor and seeing the statistical plot, containing the last 1000 values, updated in the browser on the tablet. Additionally, the user would experience a mean-delay of 74 milliseconds between the values being presented on the mobile device itself until they are presented on the tablet in the case of constant streaming from an NfcV connected sensor. The conclusion is that this delay of 74 milliseconds is sufficiently low for the user to feel that the devices are tightly coupled, making it natural to pay attention to the tablet when scanning sensors. Possible use-cases for this include a technician walking between built-in passive NfcV sensors on the factory floor or a nurse walking between patients wearing bandages with built-in passive health-sensors. Finally, the work is discussed in terms of ethics and social impact as development in the tele-healthcare field continues, and a set of Nfc-based applications are suggested including Nfc-tags for interactive product customization, company car management and app deployment.

With the advent of the telephonic and technological healthcare revolution, pharmaceutical corporations seek to improve patient compliance and quality of life by contracting with services providers. As an employee of one such provider, working for more than three years on a medication for the neurologically degenerative disease, multiple sclerosis, this investigation utilizes a mixed methodological approach. In order to improve and diversify the clinical services provided to patients, I was contracted as a consultant. I interviewed phone and PRN nurses, developed and released a PRN survey, and interviewed patients living in the Dallas/Fort Worth, Texas area. The combined experiences and expertise of the three groups who participated would serve to inform and develop new programs and services for patients with differing disease states. The research resulted in a re-imagining of the social networking theory of health, as well as the works of Pierre Bourdieu and Michel Foucault, to serve the evolving tele-health and technologically based healthcare workplace.

Bakgrund: Telefonrådgivning är ett område som ständigt växer inom sjukvården. Telefonrådgivningens syfte är att göra en bedömning avseende vilket vårdbehov som finns, ge råd, samt hänvisa den vårdsökande till rätt vårdinstans. Arbetet som telefonsjuksköterska kan vara komplext med höga krav. Klinisk erfarenhet kan således underlätta i många avseenden. Syfte: Syftet var att sammanställa sjuksköterskors erfarenheter av telefonrådgivning.Metod: En kvalitativ litteraturstudie har genomförts innehållande tio vetenskapliga artiklar som har granskats, analyserats och sammanställts. Databaserna CINAHL och PubMed användes för datainsamling. Resultat: I resultatet framkom sex teman. Exempel på teman som fångats är bland annat att ge och ta råd, dokumentation och datoriserade beslutsstöd och att medvetandegöra stressen. Att visa empati och bygga tillit med den vårdsökande var viktigt för att vinna dennes förtroende och på så vis underlätta samtalet. De datoriserade beslutsstöden lovordades men ansågs även vara ett hinder vissa gånger när den personliga erfarenheten var av annan åsikt. Konklusion: Sjuksköterskorna upplevde ofta arbetet med telefonrådgivning som givande och något som gynnade deras kompetensutveckling. Det kunde emellertid även vara stressigt och upplevas som problematiskt då resurserna var begränsade. Att läsa in och tolka vad den vårdsökande förmedlade var essentiellt eftersom de visuella ledtrådarna saknades. / Background: Telephone consulting is a field that constantly grows within health care. The aim of telephone consulting is to make an assessment regarding which health needs that exists, give advice, and refer the care seekers to the appropriate healthcare provider. The work as a telenurse can be complex with high demands. Clinical experience can therefore facilitate in many regards.Aim: The aim was to compile nurses experiences of telephone consulting.Method: A qualitative literature review was done containing ten scientific articles that has been reviewed, analyzed and compiled. The databases CINAHL and PubMed was used for data collection.Findings: In the result six different themes emerged. Examples of themes caught are among others to give and receive advice, documentation and compututerized decision support and to be aware of the stress. To show emphaty and to build trust with the care seeker were important to win their confidence and in that way facilitate the telephone consulting. The computerized decision supports were commended but was also seen as an obstacle when the personal experience were of a different opinion. Conclusion: Nurses often experienced the work of telephone consulting as rewarding and something that benefited their skills development. However, it could also be stressful and experienced as problematic as resources were limited. To read in and interpret what the care-seeking was conveyed was essential because the visual clues were lacking.

I dagens samhälle är klimatet och påverkan på miljön en av de viktigaste frågorna som bör ställas. Transportsektorn står för en stor del av de utsläpp som påverkar miljön och genom att minska utsläppen från transportsektorn kan frågor om klimatet adresseras. Arbetspendling är en del av transportsektorn och har använts som fokusområde för rapporten på grund av dess möjligheter till förändring som kommit i ljuset under Covid-19 pandemin. Syftet med rapporten är således att undersöka hur klimatpåverkan från arbetspendling kan reduceras. För detta har Järfälla kommun valts som fokusområde.  För att svara på syftet har en scenario- och litteraturstudie genomförts för att ge svar på vilka förändringar i resvanor som skett i samband med pandemin samt på vilket sätt en reducering av utsläppen relaterade till arbetspendlande kan ske. Scenariostudien utformades som en backcastingstudie vilken resulterade i fyra scenarier där samtliga beskriver sätt att nå målet om en reducering av klimatpåverkan från arbetspendling. Resultatet av studien presenteras i form av scenarier som alla ger ett svar på syftet, ‘hur kan klimatpåverkan från arbetspendling reduceras’ genom att visa effekterna av åtgärder såsom att arbeta från hemmet och begränsa möjligheten till parkering vid arbetsplatsen.  Genom att göra en scenariostudie har syftet kunnat besvaras. Däremot har flera antaganden behövts göras som påverkar resultatet. Slutsatsen som kan dras av arbetet är således att klimatpåverkan från arbetspendling kan minska genom att tillämpa åtgärder såsom hemarbete och en begränsning av antalet parkeringsplatser, men ytterligare studier bör genomföras på energianvändningens skifte från arbetsplatsen till hemmet, digitala mötens effekt på transportbehovet, arbetspendlingens klimatpåverkan utöver CO2-utsläpp och hur anställdas hälsa påverkas av hemarbetet. / In today's society, the climate and the impact on the environment is one of the most important questions that should be asked. The transport sector accounts for a large part of the emissions that affect the environment, and by reducing emissions from the transport sector, such questions about the climate can be addressed. Work commuting is part of the transport sector and has been used as a focus area for this study due to the potential for change that came to light during the Covid-19 pandemic. The purpose of this study is thus to investigate how the climate impact from commuting can be reduced. For this Järfälla in Stockholm has been chosen as the area of study.  To answer the purpose, a scenario and literature study has been conducted to provide answers to what changes in travel habits have occurred due to the pandemic and in what ways a reduction in emissions related to commuting can happen. The scenario study was designed as a backcasting study which resulted in four scenarios where all describe ways to achieve the goal of reducing the climate impact from commuting. The results of the study are therefore presented in the form of scenarios that all provide an answer to the purpose, ‘how can the climate impact from commuting be reduced’ by showing the effects of measures such as working from home and limiting the possibility of parking at the workplace.  By doing a scenario study, the purpose of the study has been answered. However, several assumptions have had to be made that affected the result. The conclusion that can be drawn from the study is that the climate impact from commuting can be reduced by applying measures such as working from home and a limitation of the number of parking spaces available, but further studies needs to be carried out regarding the shift in energy usage from the workplace to the home, the effect of digital meetings on the need for transport, the climate impact of commuting in addition to CO2 emissions and how employees' health is affected by working from home.

Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal.

Made available in DSpace on 2016-04-04T18:31:18Z (GMT). No. of bitstreams: 1 Poncinelli_Final_revisada22052007-3.pdf: 2496152 bytes, checksum: 2e7cfb0d28420c6b16ef51f9ebff00d5 (MD5) Previous issue date: 2007-04-27 / Research for the development of a process-mapping model based on control patterns to manage information technology. There is a trend for organizations to try and have their management processes under control; however, choosing, implementing and using the models which would best adapt to their reality are not easy tasks. This paper proposes the development of an information technology Management process using the systems study method named Sistemografia in order to meet the demands of the Sarbanes-Oxley law. This process is based on a model of control by objective, named Control Objectives for Information and related Technology (COBIT). All of these factors are embedded in companies that manage their technologies, especially telecommunications companies related to tele-information technology and to the multi-service nets. In short, the objectives are: to describe the elements that compose Company Management and Architecture; to describe the articles of the Sarbanes-Oxley law, relating them to the COBIT model; to describe the management model using the sistemografia method; and to propose a framework for data management and metadata for the Management of IT, associating a dashboard, and based on the maturity of the processes, so as to measure them at their present stage and plan the aimed strategic stage. / Pesquisa para desenvolvimento de um modelo para mapeamento de processos baseado em controles para a governan?a de tecnologia da informa??o. As organiza??es t?m procurado cada vez mais, ter sob controle seus processos de governan?a, por?m, escolher, adotar e utilizar modelos que melhor se adaptem ?s sua realidade n?o ? tarefa f?cil. Este trabalho prop?e o desenvolvimento de um processo de Governan?a de Tecnologia da Informa??o utilizando o m?todo de estudo de sistemas, denominado Sistemografia para atender as determina??es da Lei Sarbanes-Oxley. Tal processo est? baseado em modelo de controles por objetivos, denominado Control Objectives for Information and related Technology (COBIT). Todos esses fatores est?o intrinsecamente presentes nas empresas que fa?am gest?o de suas tecnologias, principalmente empresas de telecomunica??es que est?o relacionadas com a teleinform?tica e as redes multi-servi?o. De forma espec?fica os objetivos s?o: descrever os elementos que comp?em as Governan?a e a Arquitetura Empresariais; descrever as Se??es da Lei Sarbanes- Oxley, relacionando-as com o modelo COBIT; descrever o processo para gest?o utilizando o m?todo de sistemografia; e propor uma moldura (framework) para a gest?o dos dados e metadados para Governan?a de TI, associando um painel de controle (dashboard), baseado na maturidade dos processos, de maneira a medilos em seu estado atual e projetar o est?gio estrat?gico desejado.

Made available in DSpace on 2015-04-14T14:50:58Z (GMT). No. of bitstreams: 1 416908.pdf: 885300 bytes, checksum: 5452bf642a3ce3b68b89d90eab1512b5 (MD5) Previous issue date: 2009-07-18 / O zebrafish ? um pequeno tele?steo usado atualmente como organismo modelo em diversas ?reas das ci?ncias. As bases moleculares da neurobiologia e o genoma similar ao dos humanos proporcionam o seu uso em diversos tipos de estudos, que incluem toxicol?gicos, gen?ticos e patol?gicos. Estudos demonstraram que o d?ficit de ferro pode gerar diversos tipos de anemias enquanto seu ac?mulo pode estar relacionado com diversas patologias, como a Hemocromatose Heredit?ria, no f?gado e Doen?as Neurodegenerativas, como Alzheimer e Parkinson, no c?rebro. O sistema colin?rgico tem sido amplamente utilizado como par?metro para avaliar a a??o de agentes t?xicos e altera??o de padr?es comportamentais. A enzima Acetilcolinesterase (AChE), uma vez inibida, pode gerar um ac?mulo de acetilcolina nas sinapses nervosas e jun??es musculares, resultando em um aumento da transmiss?o excitat?ria. O gene da AChE foi clonado e seq?enciado no zebrafish. O uso crescente do zebrafish em diversos estudos envolvendo exposi??o a agentes t?xicos e f?rmacos, d? suporte a seu uso como um modelo experimental atrativo para avaliar os efeitos do ferro em diferentes tecidos. Neste sentido, o objetivo do presente estudo foi avaliar os efeitos da exposi??o a diferentes concentra??es de ferro sobre a atividade da acetilcolinesterase em c?rebro e f?gado de zebrafish adultos, assim como investigar a poss?vel correla??o destes efeitos com o conte?do de ferro acumulado em cada um dos tecidos analisados. Nos ensaios in vitro, o ferro foi capaz de promover um aumento significativo na atividade da acetilcolinesterase em c?rebro (52%) e f?gado (53%) quando os tecidos foram expostos a mais alta concentra??o de ferro testada (2.6 mM). Um aumento desta atividade enzim?tica foi observado nos ensaios in vivo, na presen?a de 15mg/L de ferro, tanto em c?rebro (62%) quanto em f?gado (70%). A an?lise de PCR semiquantitativo mostrou n?o haver modula??o nos n?veis de transcritos do gene que codifica a AchE em ambos os tecidos de zebrafish. Al?m disto, foi demonstrado que o ferro estava significativamente aumentado no f?gado quando os peixes foram expostos a 15mg/L (226%) e 150mg/L (200%), mas n?o no c?rebro. Estes resultados indicam que o ferro pode promover altera??es significativas na atividade da AchE, mas que o aumento da atividade n?o parece estar diretamente relacionado com o aumento de ferro nestes tecidos de zebrafish.

Made available in DSpace on 2015-04-14T14:51:02Z (GMT). No. of bitstreams: 1 423971.pdf: 420258 bytes, checksum: 53b4c1e4ced71be9f6cf930e265f01fb (MD5) Previous issue date: 2010-03-30 / O peixe zebra ? um pequeno tele?steo que vem sendo considerado um modelo ideal para estudos de numerosas doen?as humanas. Estudos demonstraram que muitos genes deste peixe s?o similares ao de mam?feros, inclusive humanos. Evid?ncias t?m indicado o importante papel desempenhado pelo ATP e a adenosina no sistema nervoso central (SNC). O neurotransmissor ATP ? armazenado de forma vesicular e liberado na fenda sin?ptica, onde pode agir em receptores espec?ficos localizados na membrana celular. A inativa??o do sinal mediado pelo ATP extracelular ? realizada por uma fam?lia de enzimas denominadas ectonucleotidases, incluindo as NTPDases (nucleos?deo trifosfato difosfoidrolases) e a ecto-5?-nucleotidase. Estas enzimas s?o respons?veis pelo catabolismo extracelular do neurotransmissor ATP at? adenosina. Estudos do nosso laborat?rio demonstraram a presen?a de ectonucleotidases como as NTPDases e a ecto-5?-nucleotidase no SNC de zebrafish. O objetivo deste trabalho foi investigar o efeito in vivo da exposi??o subcr?nica (96 horas) ao ars?nio sobre a atividade das NTPDases e ecto-5 - nucleotidase em c?rebro de peixe zebra, al?m de avaliar as altera??es comportamentais induzidas pelo ars?nio nesta esp?cie. Quanto aos par?metros comportamentais, houve uma diminui??o na atividade locomotora de animais submetidos a 5 mg/L de ars?nio (30,5%) quando comparado com o grupo controle, sendo que n?o houve altera??o na dist?ncia percorrida durante 5 minutos de an?lise. Durante 5 minutos de avalia??o comportamental, n?o foram observadas altera??es na velocidade m?dia e no ?ngulo do nado dos peixes em todas as concentra??es testadas de ars?nio (0,05 mg/L, 5 mg/L e 15 mg/L). O tempo gasto no ter?o superior do tanque n?o foi alterado entre os grupos testados com diferentes concentra??es de ars?nio. O tempo gasto na zona m?dia do tanque diminuiu significativamente nas concentra??es de 0,05 mg/L (55%), 5 mg/L (62%) e 15 mg/L (62%) quando comparado ao grupo controle. Al?m disso, o tempo gasto na zona inferior foi significativamente maior (28%) apenas no grupo tratado com 5 mg/L ars?nio quando comparado ao controle. Houve uma diminui??o significativa na hidr?lise de ATP na presen?a de 0,05 mg/L (37,6%), 5 mg/L (34,8%) e 15 mg/L (30,6%) de ars?nio quando comparado ao controle. O efeito inibit?rio tamb?m foi observado sobre a hidr?lise do ADP nas concentra??es de 0,05 mg/L (25%), 5 mg/L (38%) e 15 mg/L (41%) quando comparado ao controle. Com rela??o a atividade da 5 -nucleotidase, uma redu??o na hidr?lise do AMP foi promovida pelo ars?nio nas concentra??es de 50 mg/L (37,7%), 5 mg/L (26,7%) e 15 mg/L (35 %). Os resultados demonstraram que as altera??es sobre ectonucleotidases ap?s tratamentos com ars?nio podem ser um dos fatores envolvidos nos efeitos neurot?xicos e comportamentais induzidos por este contaminante no sistema nervoso central.