本研究目的為探討國內海洛因戒治人的渴求經驗，試圖檢驗藥物渴望量表(DDQ)(Franken, 2002)在台灣樣本的信效度，同時了解不同渴求構念與焦慮、憂鬱以及執行功能的關係。 首先根據過去渴求模式以及相關渴求量表發展，提出藥物渴望量表的兩個不同因素結模型，分別為模型一正增強、負增強以及控制，模型二渴望與意圖、結果預期以及控制，由探索性因素分析與驗證性因素分析結果顯示，藥物渴望量表的控制因素無法穩定反應渴求構念，但正增強與負增強、渴望與意圖與結果預期兩模型則可得到良好的支持，其中正增強與負增強之模型顯著優於單因素模型。 相關分析結果顯示，渴求的正增強與負增強兩構念皆與焦慮、憂鬱情緒達顯著正相關，淨相關分析中顯示排除正增強影響後，負增強仍與焦慮強緒有顯著相關。渴求也與執行功能中的工作記憶、訊息處理速度有顯著的負相關。研究結果初步顯示國內海洛因戒治人之不同渴求狀態與焦慮、憂鬱以及執行功能之關係，顯示在成癮治療過程中，不僅須處理渴求經驗，同時也須針對焦慮、憂鬱情緒做介入，並考慮認知功能對治療、復發的影響，以降低個案復發的風險。 / The purpose of the present study was to discuss the craving experience of heroin addicts during compulsory treatment in Taiwan. Drug Desire Questionnaire (Franken, 2002) was used to investigate different craving constructs that were positive reinforcement, negative reinforcement and control. DDQ was validated in this research. This study also examined the relationships between heroin craving, depression, anxiety and executive function. According to models of craving and research, the present study tried to examine the two models of DDQ simultaneously. Two models were also accepted but the model composed positive reinforcement and negative reinforcement was better than one-factor model. Control factor of DDQ was not validated. The result of partial correlation analysis revealed that negative reinforcement was significantly related to anxiety after control the effect of positive reinforcement. According to the results of correlation analysis, two different craving construct were also significantly related to working memory and not related to the other ability of executive function. Implications for clinical applications and future research were also suggested.

當我們在處理語句的訊息時，即使接收到的訊息是處於一種模糊不清的狀態之下，我們仍然可以藉由語境或者是儲存在長期記憶中的知識表徵來幫助我們理解語句。然而，在可以被視為一般語句處理的篇章中以及去除儲存在長期記憶的知識表徵的非篇章段落中的基本的言語的處理單位，甚少被提及。在本文中，我們將探討在兩種韻律結構的篇章語句以及非篇章為主的言語基本處理單位為何。 接著，我們將用具有心理實證的語句基本單位檢視詞彙學派以及範疇學派在句法分析上所使用的初始單位，探討哪一個學派的句法分析同時具有理論性以及實證性的證據支持。此外，經由探究韻律結構、詞語分斷之間的互動，來檢驗語言以及句法的獨立性假說。更進一步的，我們比較男女之間，對於語句提取的效率是否存有差異。分別有六男、六女，共十二名的大學生參與這次的實驗。實驗的材料是由實驗者將兩種韻律結構的篇章以及非篇章的段落分別錄音之後，讓受試者對所聽到的語句，做斷詞的工作。我們使用分斷派典以及統計考驗，來驗證本文中提出的各個假說。結果發現，在相似於我們一般說話語句的篇章中，基本處理的言語單位是詞，而在去除韻律結構以及分篇章為主的段落中，處理的基本言語單位是音節。這樣的結果符合工作記憶模式的預測。另外，詞彙學派的句法分析得到了理論上及實證上的支持。構詞、音韻、句法、以及長期記憶中的知識表徵，應該被視為是一個整體，而非句法、語言是獨立於整個認知系統之外的。至少，在本文中，利用語句產生證據來看，是反駁這個觀點的。大體上，男女之間對於語句處理的基本單位是沒有差別的，但似乎女孩子在語句產出時，更依賴韻律結構存在的與否。作者在文中提出了社會語言學的解釋。由本文可以得知，在語句產出的證據看來，詞彙句法學派得到了理論上及實證上的支持。語言是和整個認知系統互動的一種機制。而男女在提取言語單位上的效率並無不同。 / It is widely accepted that the routine of the perceptual processing of ongoing speech can be comprehended even in a degraded quality through the aid of the context or real-world knowledge stored in LTM. However, the basic units processed in the discourse-based text that can be recognized as the normal sentential input and those processed in the non-discourse-based text which removes the contribution of the knowledge representation stored in LTM are not yet investigated. In this study the basic units processed in these two textual patterns were discovered. The basic unit processed in normal prosodic, discourse-based text was employed to resolve the controversy between lexicalists’ and categorical syntacticians’ primitives of syntactic analyses. In addition, purposes of the interaction between prosodic patterns, namely the prosodic pattern, prosody-free pattern and the syntactic segmentation were examined to testify the autonomy hypotheses whether they gain the support from the speech production. Furthermore, the retrieval efficiency between genders were analyzed as well to investigate whether different genders employed different retrieval efficiency in different textual and prosodic patterns. 12 undergraduate students, six male and six female students participated in the two experiments. Discourse-based texts with two prosodic patterns and non-discourse-based pattern were recorded in the auditory form to conduct the experiments. Segmentation paradigm and statistical analysis were used to make the production analyses. Results indicated that a word is the basic unit processed in the prosodic, discourse-based text while a syllable is the basic unit processed in the prosody-free discourse-based text and non-discourse-based text which confirms to the prediction of WM model. The evidence favors lexicalists’ primitive of syntactic analysis psychologically. The cooperation between morphology, syntax, phonology and knowledge representations in general cognitive system argues against the autonomy hypotheses. Language should be recognized as a submechanism embedded in the cognitive system. The results suggested that, in general, there was no difference between genders but it seemed that female subjects tended more to rely on phonological cues. A plausible sociolinguistic reason was proposed. The results suggest that lexicalists’ primitive for syntactic analysis has theoretical as well as psychological support. In speech production, language seems to interact with other cognitive mechanisms rather than isolate to form an independent, self-contained domain. No retrieval difference exists between genders.

本研究以理學院大學數學學科能力測驗成績在7級分以上的女大學生49名作為研究對象，操弄兩種刻板印象：『女性的數學較差』與『理學院的學生數學能力較好』，結合『刻板印象威脅』與『刻板印象提升』的概念，探討一個同時具有正負向刻板印象的當事人，當被激發不同所屬團體認同（性別/科目），對於受試者工作表現、工作選擇與自我能力評估的影響，並驗證考試焦慮與工作記憶容量作為刻板印象效果的中介變項之可能性。 本研究為單因子設計，獨變項『不同認同團體激發』有三組：性別認同組、理學院認同組、控制組。依變項則有8項指標：工作記憶容量測驗分數、數學測驗分數、考試焦慮量表分數、考試焦慮生理測量、數學測驗選擇難度、數學測驗難度評估、自我評估數學能力、刻板印象相信程度。 研究結果發現，當受試者被激發理學院認同時，他們的確會受到刻板印象提升效果的影響，造成工作記憶容量上升，但當受試者被激發性別認同時，他們在工作記憶容量測驗上的表現和控制組的受試者並沒有差異，亦即，刻板印象威脅效果沒有顯現。而接受到不同認同團體激發的受試者，儘管在自陳式考試焦慮量表上並沒有顯現出差異，然而在脈搏測量上則顯現出組間差異。 另外，在『測驗難度選擇』方面，本研究發現理學院認同組的受試者較其他組受試者會選擇較困難的作業。然而，在『數學能力測驗難度評估』、『對自己能力的評估』、『刻板印象的相信程度』這三方面，不同組的受試者則沒有顯現出差異。而本研究所提出的刻板印象效果之中介機制，並未在本實驗中得到支持。最後，研究者除了對上述結果進行討論之外，亦提出本研究的限制以及對未來研究的建議。

本文研究的主要目的為研究學習行為與智能的相關性，採經驗加權吸引模型(Experience-Weighted Attraction)來描述受測者在選美競賽賽局(Beauty Contest Game)實驗下的決策及行為，不單只選擇強化學習或信念學習模型，其理由為經驗加權吸引模型綜合了以上兩個學習的特點；在智能的部分，本文以實驗所得的工作記憶能力(Working Memory Capacity)分數的高低，來代表智能高低。 　　從研究結果發現，智能高與低兩類受測者的初始吸引分配，皆與其在第一期的選擇類似，而低智能的受測者在初始吸引部分，所估計的分配結果會與第一期之後期間的分配較不相似，這可能代表著低智能的受測者對於類似賽局實驗以及此實驗的分析或想像較差；在ψ的參數估計上，由於低智能的初始吸引與最後一期猜測的分配較不相似，以理論來說會遞減較快，也就是說會小於高智能所估計的結果，而真實的估計結果也顯示如此，此外，ψ的估計結果，也表示低智能受測者，對於之前吸引遞減較快，遺忘地較快。本文在δ的部分，高智能的受測者明顯地大於低智能的受測者，這表示高智能的受測者，對於失去的報酬比較敏感，會較關心沒有選擇到的數字所能得到的報酬，本文認為此結果可能隱含高智能受測者的認知階層較高。在受測者對於吸引敏感度λ的參數部分，本研究發現，此兩類受測者並無太大差異，也就是此兩類受測者對於吸引的變動，敏感度差距不大，也就代表影響人們對於吸引敏感度的原因，可能不是來自於智商高低。由本文的實證結果，可以發現學習行為與智能的相關性，因此本文建議在往後與學習行為有關的研究上，也許可以納入智能為主要研究探討的核心。 / The purpose of this paper is to explore possible relationships between individual differences in working memory capacity (WMC) and behavioral heterogeneity revealed in a repeated beauty contest experiment. We use ‘experience-weighted attraction’ (EWA) learning, to describe the decision-making and learning behavior of subjects in the beauty contest game (BCG) experiment. In the intelligence section, the level of the experiment from the working memory capacity score, to represent the intelligence high or low. We found high and low intelligent of the subject's initial attract allocated all its similar to the first period choice. In parameter estimation of ψ, due to the initial attraction of low intelligence subject is less similar to the choice of the following periods. According to theory,ψ of the low intelligence subjects will decrease faster, and the estimate of the results also show that. In addition, part of δ, high intelligence subjects was larger than the low intelligent subjects, which means that subjects of high intelligence, more sensitive to lost revenue. We think that may be implied the higher intelligent subjects are higher cognitive hierarchy. The sensitivity of players to attractions λ, we found that these two types of intelligent is not much difference. This means that the impact of the sensitivity of players to attractions, may not be from the intelligent level. By the empirical results, we can find the relationship between behavioral heterogeneity and intelligence, so we suggests that it may be incorporated into the intelligent as the main research.

研究背景:成人午睡對於認知與情緒影響的正面效益，已獲得許多研究證實，不過兒童夜間各睡眠期所占比例與成人不同，而且至今少有兒童午睡效益的研究，因此，本研究旨在探討短暫午睡對於國小學童認知功能、學習表現與情緒狀態的影響。 實驗設計與方法:以研究一實驗室情境，配合研究二教室現場實地研究兩種方式進行探討。研究一採組內設計，以30名國小五年級學童，在睡眠實驗室分別接受單日20分鐘的午睡與清醒的實驗，並以五種神經心理測驗，進行前測與後測，並以相依樣本t考驗進行比較兩種實驗情境在五種神經心理測驗表現的差異，並以性別×情境×時間三因子變異數分析，比較睏睡度與情緒的分數差異，並以皮爾森積差相關統計分析午睡睡眠參數資料與神經心理測驗分數的相關性。研究二採組內設計，以67名五年級學童，在兩週分別接受三日教室現場的午睡以及三日清醒情境的安排，並實施國語、數學、社會教學，作為午睡效益的評量依據，並以重複樣本t考驗比較兩種實驗情境國語科、數學科、社會科學習成效測驗分數是否有所差異，另以午睡習慣×實驗情境×時間三因子變異數分析，比較睏睡度與情緒量表分數的差異性。 研究結果:研究一發現受試者經歷20分鐘的午睡後，在專心度表現顯著比清醒好，不過午睡後的抑制刺激干擾的錯誤率卻顯著比清醒時高；至於在工作記憶、敘述性記憶、程序性動作記憶的表現，兩種情境則無顯著差異。另外，發現午睡後13:10的主觀睏睡度明顯比清醒時要低，在其他情緒狀態上則無顯著差異。而且發現睡眠第一期時間與抑制刺激干擾能力表現達顯著負相關；睡眠第二期時間與敘述性記憶表現成正相關:睡眠第三期時間則與敘述性記憶表現成負相關;:研究二則發現午睡後學生睏睡度顯著比沒午睡時要低，而且三日內15:30的睏睡度皆比剛睡醒13:10時要低，且第三日15:30睏睡度有顯著降低，但其他情緒則無顯著影響。另外，國語、數學、社會三科的學習成效，在兩種實驗情境皆無顯著差異。 結論:兒童午睡過程睡眠期與成人不太相同，且從兒童夜間睡眠與認知相關研究，也可以發現兒童似乎能夠補償短暫午睡缺乏，造成對認知功能損害或情緒的負面影響，因此，短暫午睡似乎對於兒童的正面顯著效益，並不如成人ㄧ般，不過，本研究實驗室或教室研究情境，皆ㄧ致發現兒童午睡仍能減少受試者主觀睏睡度，而且也發現隨著午睡日數增加所帶來的正面效益。未來，進行實地研究可以更嚴謹的睡眠偵測及判讀工具，來確認受試者午睡情況，減少主觀判斷與檢核所產生的誤差。 / Background: It has been confirmed by many researches that taking the afternoon nap has positive effects on adult cognition and emotion. However, the proportion of children’s sleep stages at night is quite different from that of adults. Since there are few studies on the effects of children’s afternoon nap, this paper aims to discuss the effects of short nap on cognitive ability, academic performance and emotional state of elementary school pupils. Experimental Design and Methods: The study mainly adopted two methods--------- laboratory situation and field study in the classroom. The first method was conducted among 30 fifth-grade pupils from the elementary school, with each one dealing with 20-minute long nap and sober status respectively in a day. Besides, five neuropsychological tests were carried out to pre-test and post-test their performance with the paired sample t-test to compare their difference. Based on the variance analysis of gender, situation as well as time factors, sleepiness degree and emotional difference were compared and the relationship between nap parameters and neuropsychological test scores was analyzed with Pearson's correlation analysis method. The second method was conducted among 67 fifth-grade pupils from the elementary school, dealing with afternoon nap and sober situation respectively for three days in two weeks. Besides, Chinese, Mathematics and Sociology were taught as the basis to assess the effects of afternoon nap with the paired samples t-test. Based on the variance analysis of nap habits, environmental situation and time factors, sleepy degree and emotional difference were compared. Research Result: The first study showed that concentration degree of pupils after 20-minute afternoon nap was much higher than that before sleeping, so was the error rate to inhibit stimulation’s interference. As for the performance in working, declarative and procedural motor memory, there was no significant difference. In addition, we found that the subject sleepiness degree after 13:10 was lower than that when awake and there was no significant difference in other emotional states. The duration of stageⅠwas significantly negative-related to the performance to inhibit stimulation’s interference, and the duration of stageⅡwas positive-related to declarative memory performance; while the duration of stageⅢwas negative-related to declarative memory performance. The second study showed that subjective sleepiness degree of pupils after afternoon nap was much lower than that before nappinging, so was the sleepiness degree of 15:30 much lower than that of 13:10 in three days. In particular, the sleepiness degree of 15:30 in the third day decreased significantly, while other emotional states were not affected greatly. What’s more, there was no significance between these two experimental situations on study effects of Chinese, Mathematics and Sociology Conclusion: Children have a different afternoon nap course from adults. Related researches on children’s night sleep and cognition show that children seem to be able to .compensate for the lack of a short nap, resulting in cognitive impairment or emotional impact of negative.Therefore, the positive benefit of short nap of children is not as significant as that of adults. However, both laboratory and classroom situation showed that children’s afternoon nap could still reduce the subjective sleepiness. As the napping days increased, the positive effect was much more evident. In the near future, more rigorous sleep state detection and scoring tools for field study can be used to identify the nap situation and to reduce subjective misunderstanding and detection errors.

認知功能的提升是當今神經科學領域中的研究重點之一，但其神經機制尚有待釐清。本研究利用一種用於改善阿茲海默症臨床的非競爭型N-甲基-D-天門冬胺酸受體拮抗劑memantine，檢測其對於大白鼠在不同時距相關操作式制約行為及空間工作記憶行為之影響效果。實驗一為針對時間屬性的操作式制約行為實驗，運用大白鼠的區辯性增強低頻反應作業（DRL 10秒行為）與固定時距作業（FI 30秒行為）之行為作業，並操弄連續訓練與間歇訓練的兩種不同模式，測試memantine對前述四組受試的操作式制約行為在表現、消除與自發恢復等三階段之劑量反應。實驗二利用配對性延遲T迷津作業區分出不等基準線(表現好與表現差)之受試，再加以藥理實驗，測試memantine對於前述兩組受試之劑量反應。實驗一結果顯示，受試在兩種不同訓練模式下經十五次習得訓練後，在兩種操作式壓桿行為的壓桿反應相關指標中都有明顯的差異，這證實不同的行為訓練模式會導致學習後的表現有差異之別。memantine藥理實驗結果顯示，此藥對於上述四組受試的操作式行為之三階段的影響效果，會因為不同訓練模式與不同作業而異。實驗二結果顯示，memantine提高空間工作記憶的正確率在表現不好的組別有很顯著的藥效，這證實memantine對於空間式工作記憶行為的影響，也會因學習基準線的不同水平而異。在行為實驗後所進行的蛋白質表現量檢測中，memantine（5 mg/kg）只對五個測試腦區中的背側紋狀體中ERK1磷酸化程度有明顯上升的影響，而其對ERK2及CREB的磷酸化在所有腦組織中皆沒有顯著的影響。綜合以上結果，memantine影響時間與空間屬性的相關行為之藥理效果，會依行為的不同習得歷程(或行為背景經驗)及基準線表現程度而異，而此項行為藥理效果，可能與紋狀體中ERK1的磷酸化有關。 / The neural basis of cognitive enhancement is one of the intriguing topics in neuroscience research; however, the underlying neural mechanisms remain to be elucidated. This study examined the effects of memantine, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist which is used to treat Alzheimer’s disease in clinic, on operant behaviors and spatial working memory. In Experiment 1, using the differential reinforcement for low-rate-response 10 sec (DRL 10s) and the fixed-interval 30 sec (FI 30s) operant tasks, and with the manipulation of two different training regimens (continuous vs. intermittent) in the acquisition phase, the effects of memantine were evaluated in three stages of behavioral tests including the performance (right after the end of 15-day acquisition), the extinction, and the spontaneous recovery (after the extinction). In Experiment 2, memantine were tested in the subjects with different level of baseline performance (good vs. bad) on the distinctive patterns of operant responding in four different groups which received DRL 10s and FI 30s with different training regimens; indicating that behavioral task and training background are critical to the operant performance of temporal operant behaviors. Such behavioral outcomes led the dissociable effects of memantine appeared in between the four groups as tested in all three different stages. The results of Experiment 2 showed a profound improvement of the correct responses rate on spatial working memory in the low-baseline group as compared to the higher-baseline group. With a pretreatment of memantine (5 mg/kg), brain tissues in five selected areas were collected for western blot assays of ERK 1, ERK 2, and CREB. The results only revealed a significant increase of ERK 1 phosphorylation in the dorsal striatum. Together, the effects of memantine to improve cognition-associated processes in the temporal operant behaviors and the baseline of performance, and the present observation of cognition-enhancing effects of memantine may be resulted by the ERK 1 phosphorylation in the dorsal striatum.