This investigation examined the ability of the self-reported Veterans Specific Activity Questionnaire (VSAQ) and the Yale Physical Activity Survey (YPAS) to predict an individual’s performance on a timed walking assessment. Twenty subjects 65 years of age and older (73.5 ± 4.8) volunteered for the study. There were 13 women and nine men. Subjects participated in an individual interview in which the VSAQ and the YPAS were administered. The subjects then participated in a timed 25 meter walking test (16.5 ± 2.5). The 25 meter walking test was given twice and the times for each individual was averaged. Descriptive analysis of the YPAS demonstrated that the predominant reported level of energy expenditure was used for work activities (50% ± 18.4). The least amount of calories for the entire group was expended in caretaking with a mean percentage of 3.3% (± 6.1). Exercise was the second highest calorie expending category with 21.9% (± 14.0) of total calories. However, recreational activities were a close third with a mean of 17% (± 19.0). Yard work represented 7.8% (± 7.8) of total calories. The mean score for the VSAQ was 7.4 (± 3.4). The regression analysis demonstrated that age, gender, and VSAQ score were significant predictors of physical performance on the walking test (p<0.05) (Time= -1.78 +0.274 Age +2.22 Gender - 0.366 VSAQ). The r-squared value for this was 62.5%. Performance time was significantly predicted by adding the selected values from the YPAS (exercise and work) and the value from the VSAQ (Time= 18.5 - 0.566 VSAQ +0.0568 %Exer + 0.0350 %Work). The r-squared value for this was 52.6%. There was also a significant correlation (p<0.05) between age, time, and performance (r²=0.5). Therefore, the VSAQ appears to be an alternative assessment tool for physical activity in this selected elderly population. / Master of Science

Yes / Objectives: To determine whether individual goal-oriented cognitive rehabilitation (CR) improves everyday functioning for people with mild-to-moderate dementia. Design and methods: Parallel group multi-centre single-blind randomised controlled trial (RCT) comparing CR added to usual treatment (CR) with usual treatment alone (TAU) for people with an ICD-10 diagnosis of Alzheimer’s, vascular or mixed dementia and mild-to-moderate cognitive impairment (MMSE score ≥ 18), and with a family member willing to contribute. Participants allocated to CR received ten weekly sessions over three months and four maintenance sessions over six months. Participants were followed up three and nine months post-randomisation by blinded researchers. The primary outcome was self-reported goal attainment at three months. Secondary outcomes at three and nine months included informant-reported goal attainment, quality of life, mood, self-efficacy, and cognition, and study partner stress and quality of life. Results: We randomised (1:1) 475 people with dementia; 445 (CR=281) were included in the intention to treat analysis at three months, and 426 (CR=208) at nine months. At three months there were statistically-significant large positive effects for participant-rated goal attainment (d=0.97, 95% CI 0.75 to 1.19), corroborated by informant ratings (d=1.11, 0.89 to 1.34). These effects were maintained at nine months for both participant (d=0.94, 0.71 to 1.17) and informant ratings (d=0.96, 0.73 to 1.2). The observed gains related to goals directly targeted in the therapy. There were no significant differences in secondary outcomes. Conclusions: Cognitive rehabilitation enables people with early-stage dementia to improve their everyday functioning in relation to individual goals targeted in the therapy. / National Institute for Health, Health Technology Assessment Programme, Grant/Award Number: 11/15/04

Background Critical illness myopathy (CIM) and polyneuropathy (CIP) are a common complication of critical illness. Both cause intensive-care-unit-acquired (ICU-acquired) muscle weakness (ICUAW) which increases morbidity and delays rehabilitation and recovery of activities of daily living such as walking ability. Focused physical rehabilitation of people with ICUAW is, therefore, of great importance at both an individual and a societal level. A recent systematic Cochrane review found no randomised controlled trials (RCT), and thus no supporting evidence, for physical rehabilitation interventions for people with defined CIP and CIM to improve activities of daily living. Therefore, the aim of our study is to compare the effects of an additional physiotherapy programme with systematically augmented levels of mobilisation with additional in-bed cycling (as the parallel group) on walking and other activities of daily living.

OF DIPLOMA THESIS Name and surname: Bc. Lia Medková Thesis supervisor: MUDr. Yvona Angerová, Ph. D., MBA Referee: Title thesis: The effect of sensation disorders on upper limb function in patients after brain injury Abstract The aim of this thesis was to determine The effect of sensation disorders on upper limb function in patients after brain injury. Method: The research for this thesis involved non-experimental pre-research and quasiexperiments. The thesis' theoretical hypothesis was developed on the basis of previous studies that had looked at the effect of brain damage on patients' upper limb function. A total of twenty patients between the ages of 20 - 59 were selected to participate in the empirical study reported in this thesis. All participating patients had suffered damage to their cerebral cortex. The causes of their brain damage included strokes, trauma and tumor. The participants were divided into two groups of ten using the Nottingham Sensory Assessment. Participants with sensory disorders were allocated to the experimental group. Participants without sensory disorders were placed in the control group. The Jebsen-Taylor test was performed on all participants to assess their upper limb function after they had suffered brain damage. Results: Hypothesis thesis: Disorders of superficial,...

Thesis (Ph.D. (Physiotherapy))--University of the Witwatersrand, Faculty of Health Sciences, 2013. / Stroke impacts on a survivor’s ability to participate in community activities such as return to work (RTW) and affects people who are still within the working age. Return to work contributes to life satisfaction and social identity at least partly through independence gained from income-generation. The impact of RTW programmes for stroke survivors is limited and not generalisable to South Africa. This study aimed to bridge this gap in South Africa, and was conducted within the Gauteng province as it comprises the largest share of the South African population. Objectives and Methodology: The aim of the study was to determine the current practice in RTW intervention programmes for stroke survivors in the Gauteng Province of South Africa and to establish the effect of a workplace intervention programme on the rate of RTW of previously employed stroke survivors. This study had two stages: Stage one: A cross sectional survey was performed using a self administered questionnaire to establish current practice in RTW intervention programmes and the therapists’ perceived barriers and enablers of RTW after stroke. Stage two study included: a) a randomised controlled trial (RCT) to evaluate a six week RTW intervention, with follow-up at three and six months. The workplace intervention programme was tailored according to the functional ability and workplace challenges of each stroke survivor and was as follows: Week one: Assessment for work skill. The assessment included work modules which identified potential problems such as: visual discrimination; eye hand coordination; form and spatial perception; manual dexterity; colour discrimination; cognitive problems, and job specific physical demand factors. Week two: The therapist interviewed the stroke survivor and employer separately to establish perceived barriers and enablers of RTW. This was followed by a meeting between the therapist, stroke survivor and employer/supervisor to discuss and develop a plan to overcome identified barriers and to strengthen identified enablers based on consensus between stroke survivor and employer. Week three: A work visit for the stroke survivor to demonstrate what they did at work and identify what they could still do safely and what they could not do. This included vocational counselling and coaching; emotional support; adaptation of the working environment; advice on coping strategies to compensate for mobility and upper limb functional limitations; and fatigue management. Weeks four, five and six: continuation of the work visits, while monitoring progress, and making necessary adjustments as per stroke survivor and employer’s needs. This was done at the workplace while the participants continued with their usual therapy at the hospital. The control group received usual care. The primary outcome was RTW rate. The secondary outcomes included activities of daily living (measured with the Barthel Index); mobility (measured with the Modified Rivermead Mobility Index); basic cognitive function (measured with the Montreal Cognitive Assessment) and perceived quality of life (measured with the Stroke Specific Quality of life Scale). Another aim of stage two study was to: b) establish the stroke survivors’ and employers’ perceived barriers and enablers of RTW (this was done with the experimental group only); and to: c) identify predictors of RTW. Stage one study results: Thirty six (68%) of the 53 questionnaires sent to stroke rehabilitation facilities were returned. Seventeen (47%) of the 36 clinical settings referred stroke survivors to facilities offering RTW services; 12 (33%) facilities did not refer stroke survivors for RTW and did not offer RTW services; and seven (20%) facilities offered RTW services. Of the seven facilities that rendered RTW services for stroke survivors, five (71%) communicated with the employer to discuss reasonable accommodation and four (57%) did assessments for potential to RTW. The most common reason given by the 29 facilities for not offering RTW services was that they referred stroke survivors to other therapists who offered these services. The second most common reason was the unemployment status of the stroke survivor at the time of having stroke. The therapists’ most commonly perceived barriers of RTW were the severity of the stroke survivors’ physical impairments (n = 3) (36%) and their employment status (n = 11) (31%) at the time of having stroke. The most commonly perceived enablers were willingness of the employer to reasonably accommodate the stroke survivor at work (n = 12) (33%), family support (n = 8) (22%) and increased length of hospital stay to allow for intensive rehabilitation (n = 7) (19%). Stigma in the workplace was the only variable which had a statistically significant relationship with the type of clinical facility therapists worked at (p = 0.02). Stage two study results: The average age for the study group was 45 (SD: 8.7) years and the average stroke duration was 4.6 (SD: 1.8) weeks. There were 41 (51%) male stroke survivors and 39 (49%) female stroke survivors. Majority (55%) of the stroke survivors were breadwinners (63%), had a grade 11 to 12 educational level (64%), an income above R5000 (46%) and had a helper (74%) whom they did not have to pay (81%). Stroke survivors who returned to work had better quality of life at six months after stroke than those who did not RTW (p = 0.05). Results from the qualitative study indicated that the perceived enablers of RTW included: ability of the employer to provide reasonable accommodation and good interpersonal working relationships between stroke survivor, employer and co-workers. The perceived barriers of RTW included: unaffordable reasonable accommodation costs; inaccessible transport; having cognitive (memory and attention) and speech impairments and high unemployment rates. The overall RTW rate was 20% at three months follow-up and 40% at six months follow-up. Twenty seven percent of the stroke survivors in the intervention group returned to work at three months compared to 12% in the control group (p = 0.13). At six months, the majority of stroke survivors (60%) in the intervention group returned to work compared to 20% in the control group (p <0.001). The following factors were predictive of RTW: male gender (p = 0.03); fewer speech problems (p = 0.02); increased time off work post stroke (p = 0.001); ability to perform activities of daily living (p = 0.02); good mobility (p = 0.01) and good cognitive ability (p = 0.02). The stroke survivors in the intervention group were 5.2 times more likely to RTW than those in the control group at six months following stroke, and for every unit increase in the activities of the Barthel Index and Montreal Cognitive assessment score, the likelihood of RTW increased by 1.7 and 1.3 respectively. Conclusion: A RTW intervention consisting of workability assessments and workplace visits was effective in facilitating RTW for stroke survivors in Gauteng province, South Africa. Key predictors of RTW included male gender; increased time off work post stroke; ability to perform activities of daily living; good mobility and good cognitive ability and were identified as facilitating RTW; speech problems were identified as barriers to RTW. Overall, these results suggest the need to direct resources towards increasing work place intervention strategies after stroke.

Introdução: O envelhecimento populacional traz desafios, como os prejuízos de funcionalidade em tarefas rotineiras, decorrentes de condições crônicas de saúde, como a demência da doença de Alzheimer (DA). Para elaborar propostas de intervenção adequadas ao portador de DA e a sua família, a funcionalidade deve ser avaliada. O Routine Task Inventory - Expanded (RTI-E) é uma avaliação que permite avaliar o desempenho em ABVD, AIVD, Comunicação e Preparo para o Trabalho a partir da perspectiva do paciente, do cuidador e do terapeuta. Objetivo: Traduzir, adaptar transculturalmente, medir a fidedignidade e a validade da versão brasileira do RTI-E para avaliar a funcionalidade em idosos com DA. Métodos: Realizou-se a tradução e adaptação transcultural do instrumento. Utilizou-se o coeficiente ? de Chronbach para avaliar a consistência interna. A fidedignidade entre avaliadores do RTI-E foi obtida por CCI. A validade de conteúdo foi obtida por validade convergente (correlacionando a avaliações cognitivas e funcionais) e divergente (correlação com HAM-D). A validade de critério foi obtida por validade concorrente. Resultados: Foram avaliados 85 sujeitos, divididos em 42 sujeitos grupo DA (CDR=1 ou 2) e 43 sujeitos grupo controle (CDR=0) e seus pares. Obteve-se a tradução e adaptação transcultural do RTI-E, aprovada pela autora. O RTI-E demonstrou consistência interna elevada em cada escala analisada, sendo o valor mais alto em AIVD obtida por relato do cuidador (?=0,966) e alta fidedignidade entre avaliadores. O instrumento mostrou validade convergente em relação a medidas cognitivas, sendo a maior correlação encontrada em AIVD, relato cuidador (r=0,912, comparado a CAMCOG e r=0,911, comparado a MEEM). Em relação a medidas funcionais, a correlação foi muito forte em relato do cuidador (AIVD X Lawton [r= 0,917]) e em observação do terapeuta (AIVD X DAFS-Br [r=0,911]). As escalas por autorrelato mostram correlações fracas ou insignificantes. O RTI-E mostrou-se capaz de discriminar sujeitos com DA e sem DA, calculando-se áreas sob a curva ROC. Obteve-se pontos de corte variando conforme cada escala. A maior precisão (98,82%) foi encontrada em AIVD, relato cuidador, com sensibilidade 100% e especificidade 97,67%, para ponto de corte 5,26, porém, observando-se todos os valores, nota-se que o RTI-E mostra-se um instrumento mais específico do que sensível. Conclusão: Obteve-se uma versão final adaptada ao nosso meio, aprovada pela autora. O instrumento mostrou-se válido e fidedigno para avaliar a funcionalidade de idosos com DA, oferencendo informações importantes para planejamento de intervenções / Background: Population aging presents challenges, such as functional impairment in routine tasks, due to chronic health conditions, like dementia of Alzheimer\'s disease (AD). In order to design appropriate intervention programs for the AD and his / her family, functionality should be evaluated. The Routine Task Inventory - Expanded (RTI-E) is an assessment that allows evaluating the performance in AVD, IADL, Communication and Working Readiness from the perspective of the patient, the caregiver and the therapist. Objective: To translate, cross-culturally adapt, measure the reliability and validity of the Brazilian version of RTI-E to evaluate the functionality in the elderly with AD dementia compared to the elderly without cognitive impairment. Methods: Translation and cross-cultural adaptation of the instrument was carried out, aiming to maintain semantic and conceptual equivalence to the original. The Chronbach\'s ? coefficient was used to evaluate the internal consistency and interrater reliability was obtained by ICC. Content validity was obtained by convergent validity (correlation with cognitive and functional assessments) and divergent (correlation with HAM-D). Criterion validity was obtained by concurrent validity. Results: There were 85 subjects, divided into 42 subjects, AD group (CDR = 1 or 2) and 43 control group subjects (CDR = 0) and their peers. Translated and cross-culturally adapted version of the RTI-E, approved by the author, was achieved. The RTI-E demonstrated high internal consistency in each analyzed scale, being the highest value in AIVD obtained by a caregiver report (alpha = 0.966) and high interrater reliability. The instrument showed convergent validity in relation to cognitive measures, the highest correlation was found in AIVD, caregiver report (r = 0.912, compared to CAMCOG and r = 0.911, compared to MMSE). About functional measures, the correlation was very strong in caregiver\'s report (AIVD X Lawton [r = 0.917]) and in therapist\'s observation (AIVD X DAFS-Br [r = 0.911]). Self-report scales showed weak or insignificant correlations. RTI-E was able to discriminate between subjects with AD and controls. Cut-off points were obtained varying according to each scale. The highest precision (98.82%) was found in AIVD, a caregiver report, with 100% sensitivity and 97.67% specificity, for cut-off point 5,26. However, observing all values, RTI-E shows to be more specific than sensitive. Conclusion: A final version adapted to our culture, approved by the author was obtained. The instrument was valid and reliable to evaluate the functionality of the elderly with AD, offering important information for planning interventions

A artrite reumatóide é uma doença inflamatória crônica associada a alta morbidade, perda da produtividade e redução da expectativa de vida. Os pacientes requerem uma atendimento multidisciplinar para o controle da doença, reduzindo a inflamação e prevenindo a atrofia e deformação articulares. A estimulação elétrica nervosa transcutânea (TENS) tem se demonstrado no controle da dor articular, mas ainda há controvérsias sobre sua eficácia na reabilitação funcional da mão nesses pacientes. Este é um estudo cego, placebo-controlado, cruzado para comparar parâmetros funcionas da mobilidade da mão em pacientes com artrite reumatóide antes, durante e ao final de um período de 12 semanas de aplicação de TENS-burst em pontos sensitivos do membro superior. Na aplicação terapêutica utilizou-se intensidade de corrente de 10mA para estimulação das articulações metacarpofalangeanas e 20mA para os pontos sensorias do braço. Após uma pausa de um mês no tratamento, os pacientes que inicialmente receberam a estimulação terapêutica passaram a receber a estimulação placebo e vice-versa. Os resultados mostraram que a eletroestimulação terapêutica produziu mudanças positivas graduais e lineares na reabilitação funcional da mão analisado-se parâmetros de força e precisão de preensão das mãos, levando os pacientes à uma independência na execução de atividade de vida diária. O tratamento placebo mostrou-se ineficiente para a recuperação dos parâmetros avaliados. As habilidades conquistadas pelos pacientes que receberam inicialmente a eletroestimulação terapêutica foram perdidas durante o período de repouso, sugerindo que a manutenção da função da mão depende da continuidade do tratamento ao longo do tempo / Rheumatoid arthritis is a chronic inflammatory disease associated with high morbidity, loss of productivity and reduced life expectancy. Patients require multidisciplinary treatment to control the disease by reducing inflammation and preventing atrophy and joint deformation. Transcutaneous electrical nerve stimulation (TENS-burst) has been shown to control joint pain, but there is still controversy about its efficacy in functional hand rehabilitation in these patients. This is a blind, placebo-controlled, crossover study to compare the functional parameters of the mobility of the hand in rheumatoid arthritis patients before, during and after a period of 12 weeks of application of TENS- burst in the sensory points of the arm and metacarpophalangeal joints . In therapeutic application we used a current of 10mA for stimulation of joints and 20mA for the sensory points of the arm. After a month-long pause in treatment, patients who initially received therapy stimulation began receiving the placebo stimulation and vice versa. The results showed that therapeutic electrical stimulation produced gradual and linear positive changes in functional rehabilitation of the hand, accessed by analysis of strength and accuracy parameters of prehension, leading patients to independence in performing their daily living activities. The placebo treatment was inefficient for the recovery of the parameters evaluated. Skills achieved by patients who initially received therapeutic TENS-burst were lost during the rest (washing out) period, suggesting that the maintenance of hand function in rheumatoid artherits patients depends on the continuity of TENS-burst treatment

O envelhecimento da população brasileira tornou-se uma das principais preocupações dos gestores da área de saúde. Para manter o idoso com um envelhecimento ativo é necessária a preservação da independência e da autonomia. A institucionalização interfere nessa autonomia, deixando, muitas vezes, o idoso mais frágil. O objetivo deste estudo foi avaliar o nível de fragilidade de idosos que vivem em Instituições de Longa Permanência (ILPI) e sua relação com a independência funcional. Trata-se de um estudo quantitativo, observacional e prospectivo. Foram entrevistados 112 idosos residentes em ILPIs da cidade de Maceió, Alagoas. A coleta de dados foi realizada no período de agosto de 2012 a janeiro de 2013. O instrumento de coleta de dados foi composto por dados demográficos e socioeconômicos, Mini Exame do Estado Mental (MEEM), presença de comorbidades/problemas de saúde, Escala de Depressão Geriátrica (GDS), Índice de Barthel e Escala de Fragilidade de Edmonton (EFS). A análise dos dados realizou-se por meio de distribuições de frequência e de medidas de tendência central e dispersão. Estimou-se a razão de chance de prevalência para análise dos fatores associados e o teste de Correlação de Pearson para avaliar a correlação entre fragilidade e independência funcional. Os valores de p<=0,05 foram considerados estatisticamente significativos. A idade média foi de 77 anos (± 9,5 anos), predominância do sexo feminino (51,8%). A maioria era composta por idosos solteiros (41,1%), com média de 1,9 anos de estudo, 78,6% tinham renda de um salário mínimo, 58,0% recebiam visitas dos familiares, e 75,9% não eram fumantes, 77,7% referiram oito ou mais comorbidades/problemas de saúde. Quanto à independência funcional, 84,8% dos idosos eram dependentes e quanto a fragilidade 80,4% eram frágeis. A correlação do nível de independência funcional com a fragilidade dos idosos foi significante, negativa e moderada. O estudo conclui que existe uma forte relação entre fragilidade e independência funcional. Essa informação é valiosa para a prática da enfermagem gerontológica, pois oferece subsídios para o planejamento de ações específicas, com vistas à prevenção da fragilidade e manutenção da autonomia e independência do idoso institucionalizado / The aging of the Brazilian population has become one of the main concerns for administrators in the health area. Assuring aged individuals with an active aging requires the preservation of their independence and autonomy. Institutionalization interferes in this autonomy and, often, makes the aged individual even more frail. The aim of this study was to evaluate the level of frailty of aged individuals living in homes for the aged (HA) and its relation with functional independence. This is an observational prospective study using a quantitative approach, which involved interviewing 112 aged individuals living in HA in the city of Maceió, state of Alagoas. Data were collected in the period between August 2012 and January 2013. The instrument of data collection included demographic and socioeconomic data, the Mini-Mental State Examination (MMSE), the presence of comorbidities/health problems, the Geriatric Depression Scale (GDS), the Barthel Index and the Edmonton Frail Scale (EFS). Data were analyzed by means of distributions of frequency and measures of central and dispersion tendency. The prevalence odds ratio was estimated for the analysis of the associated factors and Pearson\'s correlation test was applied to evaluate the correlation between frailty and functional independence. Values of p<=0.05 were considered statistically significant. The mean age was 77 years (± 9.5 years), with predominance of women (51.8%). Most aged individuals were single (41.1%), with a mean of 1.9 years of education. 78.6% earned one minimum salary, 58.0% received visits from their relatives, 75.9% did not smoke, and 77.7% mentioned having eight or more comorbidities/health problems. Regarding functional independence, 84.8% of the elderly presented dependence and, as for frailty, 80.4% were frail. The correlation of the level of functional independence with frailty in the elderly was significant, negative and moderate. In conclusion, there is a strong relation between frailty and functional independence. This information is valuable for the practice of geriatric nursing, as it offers subsidies for planning specific actions, aiming at the prevention of frailty and the maintenance of the autonomy and independence of the institutionalized elderly individual

A esquizofrenia é uma das 25 principais causas de incapacidade em todo o mundo. Indivíduos que desenvolvem a doença apresentam prejuízos cognitivos relevantes ao longo vida. A combinação de tratamentos farmacológico e psicossocial é eficaz na melhora das dimensões psicopatológicas da esquizofrenia, porém a maioria dos pacientes apresenta importantes déficits cognitivos, principalmente em funções executivas (FE) com impacto na funcionalidade, impossibilitando uma vida independente. O método Occupational Goal Intervention (OGI) é eficaz na melhora de FE, porém não foi testado em pacientes com esquizofrenia resistente (ER). Realizamos estudo piloto cujos resultados foram descritos na dissertação de mestrado e publicados no periódico Psychiatry Research. O presente trabalho inclui o estudo completo com follow-up de 6 meses. Objetivos: Trata-se de um ensaio clínico comparando a intervenção de Terapia Ocupacional (TO), baseada no método OGI para a reabilitação de FE, com um grupo-controle de indivíduos com ER. Método: O estudo desenvolveu-se em 3 tempos: baseline, pós-tratamento e follow-up. Cinquenta e quatro pacientes com diagnóstico de ER foram randomizados e distribuídos em dois grupos: experimental e controle (placebo). O grupo experimental recebeu 30 sessões de TO com o método OGI e o grupo controle (GC) recebeu 30 sessões de atividades artesanais de livre escolha, sem intervenção ativa do terapeuta (placebo). As medidas de desfecho primário foram avaliadas pela BADS, e as de desfecho secundário pela DAFS-BR e ILSS-BR O impacto sobre a cognição foi avaliado por uma bateria neuropsicológica padrão, que mediu as seguintes funções: atenção, fluência verbal, FE, memória e o QI estimado. As escalas PANSS e o CGI foram utilizadas para monitorar a gravidade dos sintomas psicopatológicos. A eficácia foi avaliada nos três tempos do estudo por meio da análise linear de efeitos mistos e obtido o tamanho de efeito por meio d de Cohen. Resultados: Observou-se melhora significativa com tamanhos de efeito de médios a altos na BADS total (d=0,73), com pequena redução no follow-up (d=0,69).Na DAFS-BR total os tamanhos de efeito foram médios (d=0,58) porém não se sustentou no follow-up (d=0,39). Os resultados de tamanhos de efeito na ILSS-BR total foi alto (d=1,09) e com aumento de melhora clínica no follow-up (d=1,19). Não foram observadas mudanças nas funções cognitivas avaliadas pela bateria neuropsicológica. Conclusão: o método OGI mostrou-se eficaz na melhora da maioria das FE relacionadas à capacidade de controle inibitório, planejamento, resolução de problemas e flexibilidade mental de pacientes com ER quando comparado ao placebo, melhora esta que foi mantida 6 meses de seguimento / Schizophrenia is one of the top 25 causes of disability worldwide. Individuals who develop the disease have relevant cognitive impairments over a long period of time. The combination of pharmacological and psychosocial treatments is effective in improving the psychopathological dimensions of schizophrenia, but the majority of patients present significant cognitive deficits, especially in executive functions (EF) with an impact on functionality, making life independent. The Occupational Goal Intervention (OGI) method is effective in improving EF but has not been tested in patients with resistant schizophrenia (RE). We conducted a pilot study whose results were described in the master\'s thesis and published in the journal Psychiatry Research. The present study includes the complete 6-month follow-up study. Objectives: This is a clinical trial comparing Occupational Therapy (OT), based on the OGI method for the rehabilitation of EF, with a control group of individuals with RE. Method: The study was developed in 3 stages: baseline, post-treatment, and follow-up. Fifty-four patients diagnosed with RE were randomized and divided into two groups: experimental and control (placebo). The experimental group received 30 OT sessions with the OGI method and the control group received 30 sessions of free-choice craft activities without active therapist intervention (placebo). Primary outcome measures were evaluated by the BADS and secondary endpoints by DAFS-BR and ILSS-BR. The impact on cognition was assessed by a standard neuropsychological battery, which measured the following functions: attention, verbal fluency, EF, memory, and estimated IQ. PANSS scales and CGI were used to monitor the severity of psychopathological symptoms. Efficacy was assessed in the three study times by means of the linear analysis of mixed effects and the effect size obtained by means d of Cohen. Results: A significant improvement was observed with mean to high effect sizes in the total BADS (d = 0.73), with a small reduction in follow-up (d = 0.69). In DAFS-BR total effect sizes were medium (d = 0.58) but did not sustained at the follow-up (d = 0.39). The results of effect sizes in the total ILSS-BR were high (d = 1.09) and with an increase in clinical followup at follow-up (d = 1.19). No changes were observed in the cognitive functions evaluated by the neuropsychological battery. Conclusion: the OGI method proved to be effective in improving the majority of EF related to inhibitory control capacity, planning, problem-solving, and mental flexibility of RE patients when compared to placebo, which was maintained 6 months after follow-up

Objetivos: Avaliar a capacidade funcional de pacientes vítimas de trauma um ano após alta hospitalar e verificar associação da capacidade funcional com fatores relacionados ao trauma e à internação hospitalar. Metodologia: Estudo de coorte prospectivo, com pacientes vítimas de trauma grave (Injury Severity Score - ISS >=16), internados entre Junho e Setembro de 2010 em unidade de terapia intensiva (UTI) cirúrgica especializada em paciente politraumatizado de um hospital público de grande porte na cidade de São Paulo, Brasil. Variáveis de interesse como idade, sexo, escore de Glasgow, Acute Physiology and Chronic Health Disease Classification System II (APACHE II), mecanismos de trauma, número de lesões, região corpórea afetada, número de cirurgias, duração da ventilação mecânica (VM) e tempo de internação hospitalar foram coletadas dos prontuários médicos. A capacidade funcional foi avaliada um ano após alta hospitalar utilizando as escalas Glasgow Outcome Scale (GOS) e Escala de Atividades Instrumentais de Vida Diária de Lawton (AIVDL). Os pacientes também foram questionados se haviam retornado ao trabalho ou estudo. Resultados: O seguimento um ano após trauma foi completo em 49 indivíduos, a maioria composta por jovens (36±11 anos), do sexo masculino (81,6%) e vítimas de acidentes de trânsito (71,5%). Cada indivíduo sofreu aproximadamente 4 lesões corporais, acarretando uma média no ISS de 31 ± 14,4. O traumatismo cranioencefálico foi o tipo de lesão mais comum (65,3%). De acordo com a GOS, a maioria dos pacientes apresentou disfunção moderada (43%) ou disfunção leve ou ausente (37%) um ano após o trauma. A escala AIVDL apresentou pontuação média de 12±4 com aproximadamente 60- 70% dos indivíduos capazes de realizar de forma independente a maioria das atividades avaliadas. Escore de Glasgow, APACHE II, duração da VM e tempo de internação hospitalar foram associadas com a capacidade funcional um ano após lesão. A regressão linear múltipla considerando todas as variáveis significativas revelou associação entre a pontuação da escala AIVDL e o tempo de internação hospitalar. Apenas 32,6% dos indivíduos retornaram ao trabalho ou estudo. Conclusões: A maioria dos pacientes vítimas de trauma grave foi capaz de realizar as atividades avaliadas com independência; apenas um terço deles retornou ao trabalho e/ou estudo um ano após alta hospitalar. O tempo de internação hospitalar foi revelado como preditor significativo para a recuperação da capacidade funcional um ano após lesão grave / Objectives: To investigate the functional capacity of trauma survivors at one year after hospital discharge and to verify the association between functional capacity and trauma-related aspects and hospital stay. Methods: This prospective cohort study included severe trauma patients (Injury Severity Score - ISS >= 16) admitted between June and September 2010 to a surgical intensive care unit (ICU) of a large public hospital in São Paulo, Brazil. Variables of interest such as age, gender, Acute Physiology and Chronic Health Disease Classification System II (APACHE II), trauma mechanisms, number of injuries, body region injured, number of surgeries, mechanical ventilation (MV) duration and hospital length of stay (LOS) were collected from patient records. Functional capacity was assessed one year after hospital discharge using the Glasgow Outcome Scale (GOS) and the Lawton Instrumental Activities of Daily Living Scale (LIADL). Patients were also asked if they had returned to work or school. Results: A total of 49 trauma survivors completed 1 year of follow-up. Most subjects were young (36±11 years), male (81.6%) and victims of traffic accidents (71.5%). Each patient suffered approximately 4 injuries, with a mean ISS of 31 ± 14.4. Traumatic brain injury was the most common type of injury (65.3%). According to the GOS, most patients were classified into two categories, indicating moderate dysfunction (43%) or mild or no dysfunction (37%) at one year after trauma. Additionally, the LIADL also showed favorable functional outcomes (average score 12 ± 4); approximately 60-70% of the subjects were able to perform most activities independently. Glasgow score, APACHE II score, MV duration and hospital LOS were factors related to the recovery of functional capacity one year after injury. Multiple linear regression analysis including all variables with statistical power revealed a significant association between the LIADL score and hospital LOS. Only 32.6% of the subjects had returned to work or school. Conclusions: Most severe trauma patients were able to perform the assessed activities independently, although only a third had returned to work or school one year after hospital discharge. Hospital LOS was identified as a significant predictor of functional capacity recovery one year after severe injury