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The problem with which this study is concerned is that of comparing the results of teaching community college students enrolled in a transferable mathematics sequence for business and economics majors by a computer-aided instructional program and by the traditional lecture method. In order to effectively resolve this problem, an A Programming Language System 360 (APL/360)-aided instructional program was developed and an experimental study was conducted. The APL/360-aided instructional program consisted of three sets of materials.: a manuscript on APL/360, a list of APL programs defining operators relevant to a computer-aided study of calculus, and a collection of problems based on these programs and calculus concepts. The subjects for the experiment were forty-four students enrolled in three sections of Mathematics 112 at Mountain View College of the Dallas County Community College District. The control group, students taught by the traditional lecture method, consisted of twenty-one students. The experimental group, students taught by the APL/360-aided instructional program, consisted of twenty-three students. The same instructor taught all students. The essential difference in the two teaching methods was the use of the computer as a teaching-learning aid in the computer-aided instructional program. The computer was a course supplement to classroom instruction and aided students in obtaining insight into the nature of mathematical concepts as well as serving as a computational aid.

DOCTORAL THESIS 2012 POKORNA Abstract We have used a well characterized transplantable transgenic mouse model which mimics human acute promyelocytic leukemia (APL), both in its biological characteristics and its response to conventional therapeutic drugs. The aim of our study was to better characterize the efficacy of the combined treatment and to determine molecular markers of clinical outcome. We established a minimal residual disease monitoring based on the high sensitivity of detection of PML-RAR transcripts by polymerase chain reaction (PCR) technology in APL mice. We showed that oncogene-specific PCR-based assays allow, like in patients, the diagnosis, follow-up and prediction of disease evolution. Furthermore, PCR assay was used to assess various tissues and organs for the presence of PML-RAR-positive cells in minimal residual disease free long-term survivors. As expected, majority of mice had no measurable tissue level of PML-RAR demonstrating the efficacy of immunotherapy. However, tracking the oncogene-positive cells reveals for the first time that extramedullary PML-RAR-positive cell reservoirs such as the brain may persist and be involved in the leukemia relapse. We aimed at investigating the immune responses involved in the anti-leukemic effect of the combined immutherapy. To evaluate the...

Made available in DSpace on 2015-03-05T18:38:01Z (GMT). No. of bitstreams: 0 Previous issue date: 18 / Nenhuma / Este estudo teve por objetivo analisar o setor metal mecânico do Vale do Rio do Sinos no Estado do Rio Grande do Sul, avaliando sua competitividade. O setor é composto por 1157 empresas e disponibiliza 20.620 empregos diretos, com predominância de micro e pequenas empresas, representando 97,06% do total, as quais produzem para os mais diversos setores da economia, porém com a peculiaridade de uma boa parcela deste montante estar focado para o APL do calçado, demonstrando uma dicotomia no setor. Os dados foram obtidos através de um questionário, elaborado a partir das características da competitividade, crescimento e diversificação e aplicado em 9 empresas, sendo 4 delas atuando no APL do calçado e as outras 5 fora do APL, portanto produzindo para vários setores da economia, como o setor agrícola, moveleiro, automotivo, petrolífero, estrada e infra-estrutura, mineração, entre outros. Ao se defrontarem as características da competitividade, conforme proposto no estudo, se observou uma semelhança em muitas es / This paper aims at analyzing the metal mechanic industrial complex located in the Vale do Rio do Sinos, Rio Grande do Sul State, Brazil, by evaluating its competitivity. The complex is made of 1157 companies, which generate 20.620 direct jobs, being 97, 06% of them micro and small companies producing to different sectors of the economy. However, most of these companies integrate the local productive systems (clusters) related to the shoe industry, this fact shows a sector dichotomy. A questionnaire based on competitivity, growth and diversification was applied to 09 companies - 04 of them integrate the local productive system related to the shoe industry, and the other 05 produce to different sectors of the economy: agribusiness, furniture industry, oil companies, mining, roads and infrastructure, mainly . In terms of competitivity, it has been noticed that companies apply similar strategies; however, the ones integrating the local productive system present small competitivity variation, showing that such

Made available in DSpace on 2015-04-22T22:10:34Z (GMT). No. of bitstreams: 1 Nadja Polyana Felizola Cabete.pdf: 625813 bytes, checksum: fa399dcf5ca145eba4bd4629fdbbff14 (MD5) Previous issue date: 2009-10-30 / Trying to find ways for regional development, proposals are suggested to incentivate clusters in the suburbs. These clusters, conventionally called in Brazil of Arranjos Produtivos Locais, represent a chance of economic and social development for these regions, since that organized and structuralized, what it can be defined by its maturity level. However, it depends on the performance of the companies, its organization and the relashionship created inside cluster. The approach of this work is developing a model for evaluate the real development situation of the companies inside these clusters, through a research based on the bibliography review and some important works developed about this subject, that are base for a half-structuralized interview that can be able of identify the possible situations that companies could present. This model can influenciate the companies to plan strategies for reaching better levels of development and help them to contribute in significant way for increasing the cluster maturity level / Em busca de alternativas para alavancar o desenvolvimento regional, surgem propostas de incentivos aos aglomerados produtivos instalados em regiões menos favorecidas do país. Esses aglomerados, convencionalmente chamados no Brasil de Arranjos Produtivos Locais, representam uma oportunidade de desenvolvimento econômico e social para essas regiões, desde que organizados e estruturados, o que pode ser definido pelo nível de maturidade em que os mesmos se encontram. Porém, o alcance de um maior nível de maturidade depende consideravelmente do desempenho das empresas inseridas no arranjo, da forma com que elas se organizam e se relacionam para alcançar seu próprio desenvolvimento e do todo. A proposta deste trabalho é criar um modelo que auxilie no diagnóstico do desenvolvimento destas empresas de forma clara e objetiva, a partir de uma pesquisa exploratória, com a realização de um levantamento teórico sobre o tema e a realização de uma entrevista semi-estruturada, de caráter preditivo das possíveis situações em que a empresa possa se encontrar. Baseadas nos resultados obtidos nesta pesquisa, as empresas poderão visualizar sua realidade e traçar estratégias para alcançar níveis maiores de desenvolvimento e desta forma contribuir de maneira mais significativa para o aumento do nível de maturidade do arranjo

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2017-04-13T12:36:54Z No. of bitstreams: 1 2009 - Paulo Rodrigues F.Pereira.pdf: 1153982 bytes, checksum: f420a46faa32f113b20b2eb3d96c7023 (MD5) / Made available in DSpace on 2017-04-13T12:36:54Z (GMT). No. of bitstreams: 1 2009 - Paulo Rodrigues F.Pereira.pdf: 1153982 bytes, checksum: f420a46faa32f113b20b2eb3d96c7023 (MD5) Previous issue date: 2009-08-10 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / This study was developed based on the introduction of the Banana local production system at Rio de Janeiro state, according to the cluster theory, aiming to support the sustainable development of the region, that is facing fierce competition from the products coming from other regions in Brazil. In this situation a professional marketing management, using the right distribution channels, thus the recognition of the product value attributes may generate real competitive advantages to de local banana production system. Although Rio de Janeiro is the country?s second largest internal consumer, state production hasn?t found a receptive local market. While logistical costs are lower, local production doesn?t meet the visual characteristics consumers are looking for and as a result finds itself well below the market?s demands. The object of this dissertation is to identify the fruit?s level of competitiveness within the value chain?both in its natural state, as well as that of products derived from it?according to the markets new commercialization standards, in order to revert the strangulation points present in production today. The methods used to map out the difficulties found in the production chain include field research, questionnaires, and interviews with producers and final consumers. The results found point to the technical deficiencies of production without modern cultural treatments and distance between producers when it comes to the sale of natural or industrialized products which makes them competitors rather than partners in a cluster. Products derived from bananas could present a solution, both in regards to products that currently aren?t being sold due to an excess of bananas on the market, as well as for producers who lack the means to compete in a market where high-tech products with a more attractive appearance are found. This study allows the identification of the deficient agents in the production chain and presents a proposition of new solutions and Technologies to enhance the cluster formation, be it in the formation of producers associations or other forms of cooperative behavior in search for the implementation of new solutions. The use of information that may aggregate value to the products and stimulate professional sales may generate marginal incomes to the producers, configuring as a solution to the impoverishment of the families who depend of these incomes to survive. Also the decline of the banana culture has led to a environmental problem and to the real state speculation. Nevertheless the solution to revert this situation lies on the implementation of the local produce system based on clusters theories the adoption of more Professional culture techniques avoiding a uncertain future to this local production system / Este trabalho foi realizado com base na implanta??o do APL da Banana Org?nica do Estado do Rio de Janeiro que tem como objetivo apoiar o desenvolvimento sustent?vel da produ??o da banana na regi?o, entrando em recupera??o frente a bananicultura de outros estados; e uma comercializa??o mais profissional, nos canais de distribui??o corretos e com a valoriza??o dos elos produtivos poder? trazer uma real vantagem competitiva ao APL. Apesar do Rio de Janeiro ser o segundo maior consumidor interno, a produ??o n?o encontra no estado um mercado receptor, mesmo tendo um custo log?stico inferior, o produto n?o atende ?s caracter?sticas visuais que se apresentam muito abaixo das exig?ncias do que o mercado consumidor busca. O objetivo nesta disserta??o consiste em identificar na cadeia de valor a competitividade da fruta in natura e dos derivados da banana frente aos novos padr?es de comercializa??o do mercado, revertendo os pontos de estrangulamento hoje existentes na produ??o. A metodologia de trabalho utilizada para mapear as dificuldades da cadeia produtiva foi aplicar pesquisas de campo com uso de question?rios e entrevistas com produtores e consumidores finais. Os resultados encontrados apontam para as defici?ncias tecnol?gicas da produ??o sem uso dos modernos tratos culturais e do distanciamento dos produtores entre si, na hora de vender o produto in natura ou o produto industrializado, transformando-os em concorrentes e n?o parceiros de um cluster. Os derivados de banana poder?o ser uma solu??o para os produtos que ora n?o s?o vendidos pelo excesso de oferta e para os produtos que n?o apresentam condi??es de disputar um mercado concorrido com produtos de alta tecnologia e apar?ncia agrad?vel ao consumidor. Este trabalho permitiu identificar na cadeia produtiva elos deficientes que resultaram numa proposta com aporte de novas tecnologias em solu??es que fortale?am o que poder? ser um cluster, seja na forma??o de associa??es de produtores ou outros grupos onde todos possam cooperar na busca e implanta??o das solu??es. A utiliza??o de informa??es que possam agregar valor aos produtos e trazer profissionalismo na venda poder?o gerar uma renda marginal para a comunidade, sendo a solu??o para reverter um quadro de empobrecimento das fam?lias que hoje dependem desta cultura, mas que convivem com renda a cada dia menor. A decad?ncia da cultura da banana levou para a regi?o o problema ambiental e a especula??o imobili?ria, mas uma solu??o para reverter este quadro se apresenta na implanta??o do APL da banana org?nica da regi?o da Costa Verde, transformando-a numa cultura mais profissional.

Le langage APL a été défini en 1962 par K.E. Iverson dans un ouvrage intitulé " A Programming Language " [Iverson62]. En dépit des difficultés nouvelles que ce langage posait aux concepteurs, des interprètes APL furent rapidement disponibles chez I.B.M. [Chomat71, Iverson73]. Ce langage s'étant d'emblée révélé intéressant pour toutes les applications réclamant plus de programmation que de longs calculs, plusieurs systèmes virent le jour chez d'autres constructeurs [Martin72, Girardot76]. Réalisés pour la plupart sur de gros ordinateurs, ils réclament des ressources hors de proportion avec les moyens habituels mis à la disposition des ingénieurs ou des étudiants. Parallèlement de nombreux travaux de recherche ont été menés afin d'accélérer l'interprétation du langage. P.S. Abrams fut le premier à introduire certaines notions fondamentales d'optimisation comme le beating devenu classique de nos jours. Il a également envisagé la construction d'un matériel muni d'un code machine très voisin du langage APL [Abrams70]. D'autres approches ont consisté à réaliser un maximum de fonctions au niveau matériel, en microprogrammant un sous-interprète scalaire ou vectoriel, et en rédigeant ensuite, dans l'APL restreint ainsi obtenu, l'interprète complet. L'étude des divers systèmes existants montre que les architectures purement logicielles, utilisant presque toujours une technique d'interprétation naïve sont les plus répandues. Cependant, même si les architectures sont restées identiques, l'évolution des techniques d'implantation a permis des progrès considérables. De fait, il semble assez difficile de progresser beaucoup dans une voie purement logicielle si ce n'est par des approches radicalement différentes comme celles décrites dans [Hewlett77]. Ce système APL réalisé sur HP 3000 est en fait un compilateur incrémental générant pour chaque ligne de code qu'il exécute pour la première fois, un fragment de code machine. , Une signature associée à ce code permet de savoir ultérieurement si la réutilisation de ce code est possible.

The prohibition of the anti-personnel landmines in 1997 have caused a great debate. The debate itself is quite unilateral, where it is mainly the supporters of the prohibition who is creating scien-tific contribution to the subject. The debate is also directed to if and why a nation should ratify the ban on antipersonnel mines, and because of that, the discussion of how a nation have or could have ratify it has been forgotten. This study examines how the Swedish counter-mobility regulations has changed after the ratification of the Ottawa-convention and the elimination of the anti-personnel mines. The purpose of this essay is to increase the knowledge how the Swedish armed forces have adapted to the ratification of the Ottawa-convention and in the long run contribute to the under-standing on how a political/humanitarian decision can affect the fighting power of a smaller nation as Sweden. Through analysis of Swedish counter-mobility regulations, it shows that some adaptations have been made, however there is still some unbalance between the methods/tactics and the available landmine equipment which results in less than maximum effect is produced with the counter-mobility actions.

Submitted by Roger Guedes (roger.guedes@fjp.mg.gov.br) on 2013-08-22T13:50:33Z No. of bitstreams: 2 A espiral do conhecimento inter-organizacional.pdf: 1481806 bytes, checksum: 3e6825f2c1fe7e409117d77e41ffbba5 (MD5) license_rdf: 23599 bytes, checksum: 9e2b7f6edbd693264102b96ece20428a (MD5) / Approved for entry into archive by Roger Guedes (roger.guedes@fjp.mg.gov.br) on 2013-08-22T13:51:47Z (GMT) No. of bitstreams: 2 A espiral do conhecimento inter-organizacional.pdf: 1481806 bytes, checksum: 3e6825f2c1fe7e409117d77e41ffbba5 (MD5) license_rdf: 23599 bytes, checksum: 9e2b7f6edbd693264102b96ece20428a (MD5) / Made available in DSpace on 2013-08-22T13:51:47Z (GMT). No. of bitstreams: 2 A espiral do conhecimento inter-organizacional.pdf: 1481806 bytes, checksum: 3e6825f2c1fe7e409117d77e41ffbba5 (MD5) license_rdf: 23599 bytes, checksum: 9e2b7f6edbd693264102b96ece20428a (MD5) Previous issue date: 2006 / Funda????o Jo??o Pinheiro / Esta pesquisa examinou um agrupamento produtivo de confec????es no sentido de verificar sua constitui????o enquanto arranjo produtivo local (APL). Pesquisamos sua hist??ria enquanto agrupamento produtivo e a constru????o de sua cultura coletiva, verificando seu grau de coopera????o e compartilhamento informacional. Identificamos na sua vis??o compartilhada de mundo um conte??do informacional que os agrega, relacionados a sua pr??tica produtiva cotidiana. Sugerimos, finalmente, interven????es no agrupamento que permitam aumentar o grau de confian??a e coopera????o, o que pode ampliar a troca de informa????es, o aumento do aprendizado coletivo, a gera????o de inova????es e o conseq??ente fortalecimento do arranjo produtivo local. / This research examineted a small local industries group in order to verify its constitucion as a cluster. Researched its history while a cluster and the construction of its coletive culture, verifying its grade of cooperation and information sharing. Identifying the way they see the world was found an informational content that keeps them together related to its daily production practices. Sugested, finally, interventions in the cluster that allows the raise of trust and cooperation grades, which may amplify the exchange of information, the raise of coletive knowledge, the creation of inovation and, consequently, its strength. / Ci??ncia, Informa????o e Comunica????o

Made available in DSpace on 2014-06-11T19:24:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-09-28Bitstream added on 2014-06-13T18:51:29Z : No. of bitstreams: 1 ruiz_er_me_bauru.pdf: 1253533 bytes, checksum: ec8453a71add632b9eefd8d8002be43f (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / O objetivo desta pesquisa é analisar a gestão da comunicação, das empresas do Arranjo Produtivo Local (APL) de Brinquedos de Laranjal Paulista e Região, entendida como forma efetiva de aumento da competitividade mercadológica e eficiência empresarial do setor em que atuam. A identificação de eventuais pontos de estrangulamento possibilita o aprimoramento dos processos de comunicação utilizados, bem como a disseminação dos mesmos, junto ao APL. Os dados obtidos através da aplicação de um questionário tornou possível analisar a gestão da comunicação do APL de Brinquedos de Laranjal Paulista e Região, e a sua importância para a melhoria da competitividade mercadológica e eficiência das empresas, minimizando o distanciamento entre os empresários bem como das informações imprescindíveis à atuação do APL. Foram pesquisadas 13 empresas fabricantes de brinquedos porque elas se constituem nas mais atuantes para o APL em questão. Dentre as conclusões obtidas, pode-se evidenciar a inexistência de um setor de comunicação formalmente constituído, a grande preocupação com a comunicação informal distorcida, a percepção da necessidade de melhoria do processo comunicativo, e por fim, a constatação que a comunicação externa adequada às empresas minimiza o distanciamento entre os empresários, aumentando a competitividade e a eficiência empresarial. / The objective of this research is to analyze the management of the communication, of the companies of local producer system (cluster) of Toys of Laranjal Paulista and Region, understood as form accomplishes of increase of the marketing competitiveness and enterprise efficiency of the sector where they act. The identification of eventual points of strangulation makes possible the improvement of the used processes of communication, as well as the dissemination of the same ones, next tot he cluster. The data gotten through the application of a questionnaire became possible to analyze the management of the communication of the cluster of Toys of Laranjal Paulista and Region, and its importance for the improvement of the marketing competitiveness and efficiency of the companies, minimizing the distances enters the entrepreneurs as well as of the essential information to the performance of the cluster. Thirteen companies had been searched manufacturers of toys because they consist in most operating for the cluster in question. Amongst the gotten conclusions, she can yourself be cited the inexistence of a sector of communication formal consisting, the great concern with the distorted informal communication, the perception of the necessity of improvement of the communication process and finally the verification that the external communication adjusted the companies minimizes the distance between the entrepreneurs, increasing the competitiveness and the enterprise efficiency.