Biomass is a valuable and limited resource that should be used efficiently. The potential of replacing fossil-based products with bio-based ones produced in biobased industrial systems is huge. One important aim of increasing the share of biobased products is to improve the sustainability of systems for production and consumption. Therefore, it is important to evaluate what solutions are available to improve the sustainability performance of bio-based industrial systems, and if they also bring negative impacts. The thesis focuses on assessing the role of biogas solutions in developing sustainable bio-based systems. Such assessments are often quite narrow in their scope and focus on quantitative environmental or economic aspects. This thesis aims at also including feasibility related aspects involving the contextual conditions that are assessed more qualitatively. Biogas solutions are identified as a versatile approach to treat organic materials which are generated in large volumes in bio-based industrial systems. The results show that biogas solutions in bio-based industrial systems (i) improve circular flows of energy and nutrients, (ii) are especially viable alternatives when the quality of the by-product streams become poorer, and (iii) may improve the profitability of the bio-based industrial system. To perform better assessments of these systems, it seems valuable to broaden the set of indicators assessed and include feasibility-related indicators, preferably through the involvement of relevant stakeholders as they contribute with different perspectives and can identify aspects that influence the sustainability in different areas. Future studies could benefit from applying those broader assessments on more cases to build on a more generalisable knowledge base.

Le couplage d’une oxydation en voie humide (OVH) et d’un réacteur à biofilm aérobie en lit fixe (PBBR) a été étudié afin d’évaluer sa faisabilité pour le traitement d’un effluent donné et de modéliser le procédé couplé en vue de l’évaluation de ses performances énergétiques et de son coût d’investissement. Deux composés modèles ont été choisis : le phénol, représentatif des margines, et le colorant Acid Orange 7, représentatif de certains effluents textiles.Tout d'abord, l’OVH du composé modèle a été étudiée afin de sélectionner des conditions permettant la formation d’un effluent adapté au traitement biologique. Des PBBR ont ensuite été développés : l’influence de l’acclimatation et de la configuration du réacteur a été étudiée. Enfin, les PBBR ont été alimentés par l’effluent d'OVH afin de conclure sur la faisabilité du procédé couplé. Dans un second temps, l’OVH du composé modèle a été simulée sur ProsimPlus via des données thermodynamiques, hydrodynamiques et cinétiques. Un modèle de PBBR a été développé à partir de données physiques et cinétiques issues de la littérature, validé expérimentalement, puis implémenté sur ProsimPlusl. Ainsi, le traitement par procédé couplé OVH – PBBR des effluents sélectionnés a été simulé. Dans les deux cas, la faisabilité du couplage a été montrée expérimentalement, le PBBR permettant d’affiner le traitement du composé modèle et/ou du COT, avec des abattements jusqu’à 99% et 96% respectivement. De plus, via les simulations, un bilan énergétique positif a été calculé – montrant le potentiel autothermique du procédé couplé – ainsi qu’une économie significative sur le coût d’investissement de l’OVH, validant ainsi l’intérêt du couplage. / Coupling Wet Air Oxidation (WAO) with an aerobic Packed-Bed Biofilm Reactor (PBBR) has been studied, firstly to assess its feasibility to treat a given effluent, and secondly to develop a coupled-process modeling and simulation in order to evaluate its energetic performance and investment cost. Two model compounds were selected: phenol, representing margins, and Acid Orange 7 dye, representing some textile effluents. First of all, WAO of model compound was studied to select operating conditions leading to an effluent which was adapted to biological treatment. Then, PBBRs were implemented: effect of acclimation to the model compound and effect of reactor configuration (upflow or downflow) were studied. Finally, the PBBRs were fed with the pre-oxidized effluent, allowing to conclude on the feasibility of the coupled process. Furthermore, simulation of WAO of model compound was carried out on ProsimPlus® software thanks to thermodynamics, hydrodynamics and kinetics data from literature and/or experiments. As well, a PBBR model was developed using literature physics and kinetics data, it was then experimentally validated and implemented on ProsimPlus®. Thus, simulations of the treatment by WAO – PBBR coupled process of the selected effluents were undertaken. In both cases, feasibility of the coupled process was experimentally established: biological reactor improved treatment of model compound and/or TOC, with yields up to 99% and 96% respectively. Besides, simulations allowed to assess a positive energy balance – indicating a potentially autothermic process – and a significant gain on WAO investment cost, so that the interest of coupling WAO and PBBR was demonstrated.

LIDER CHICLAYO S.A. es una organización que tiene como objetivo posicionarse en el sector vivienda y es por eso, que presenta el proyecto inmobiliario “Condominio TERRANOVA” a desarrollarse en un terreno de 6,200 m2, ubicado en el distrito de Pimentel, provincia de Chiclayo, departamento de Lambayeque. Este proyecto se encuentra dentro de los lineamientos del plan estratégico de la empresa, pretendiendo consolidar el mercado en la región norte del Perú; para realizar en el futuro proyectos de mayor envergadura o similares, utilizando la Dirección de Proyectos en cada etapa sin sobrepasar los presupuestos, sin mayores retrasos y sin dejar de lado la calidad del trabajo y producto. Este proyecto tendrá una duración de 27 meses; de los cuales, los 3 primeros meses será de trabajos pre operativos, 9 meses de preventas y 9 meses de ventas. Luego la construcción tendrá una duración de 9 meses y luego 7 meses de post venta. Para lo cual se tiene presupuestado una inversión de 23´ 511 826.00 millones de soles; cuya distribución está dada por Aportes de Promotores, Ventas y Financiamiento Bancario. Se tiene proyectada una utilidad de 2´468 086.00 millones de soles, y una TIR del 25.59% Durante los siguientes ocho capítulos a desarrollar en la presente tesis se comprobará la factibilidad tanto técnica, económica y financiera de la dirección de proyectos inmobiliarios que implica la construcción de edificios. La estructura de este documento ha sido desarrollada de acuerdo a los cinco grupos de procesos de un proyecto. / LIDER CHICLAYO S.A. is an organization that aims to position itself in the housing sector and that is why it presents the real estate project "Condominio TERRANOVA" to be developed on a 6,200 m2 land, located in the district of Pimentel, province of Chiclayo, department of Lambayeque. This project is within the guidelines of the company's strategic plan, seeking to consolidate the market in the northern region of Peru; to carry out larger or similar projects in the future, using Project Management at each stage without exceeding budgets, without major delays and without neglecting the quality of work and product. This project will last 27 months; of which, the first 3 months will be pre-operational work, 9 months of pre-sales and 9 months of sales. Then the construction will last 9 months and then 7 months of post sale. For which an investment of 23´ 511 826.00 million soles has been budgeted; whose distribution is given by Contributions of Promoters, Sales and Bank Financing. A profit of 2'468 086.00 million soles is projected, and an IRR of 25.59% During the following eight chapters to be developed in this thesis, the technical, economic and financial feasibility of managing real estate projects involving the construction of buildings will be verified. The structure of this document has been developed according to the five groups of processes of a project. / Tesis

No description available.

Abstract This thesis aims to explore the impact of municipal sustainability policy requirements on the feasibility - the viability or practicality of the realization - of housing development projects, by using the perspectives of the municipality, housing developers, and institutional investors. By using this three-point perspective, this thesis aims to shed light on the intricate dynamics between these stakeholders, and the implications of municipal policy requirements on the project feasibility. Therefore, the study seeks to uncover perceived challenges from the housing developers and identify potential areas for improvement in the policy implementation. The municipality of Eindhoven in the Netherlands is used as a case study. The study uses principal-agent theory and employs a qualitative analysis method, to gain new insights into the effectiveness of policy implementation, the interplay and collaboration between the different stakeholders, the collaboration, and investment strategies of institutional investors. The study concludes that collaboration between the housing developers and the municipality is a key factor in overcoming barriers and creating feasible housing development projects. Building trust, recognition for each other’s interests, and sharing risks and responsibilities are crucial elements. As well as stability in the policy implementation, which is identified as a key factor in safeguarding ongoing development projects from unexpected costs and delays. Aligning policy requirements with consumer needs, fostering trust and understanding between the stakeholders, and creating some sort of ‘transition policy’ are the key takeaways from this study. Ultimately, the study aims to contribute to effective policy implementation, improved collaboration, and accelerating the housing supply. / Sammanfattning Denna uppsats undersöker hur kommunala hållbarhetskrav påverkar genomförbarheten av bostadsutvecklingsprojekt genom att belysa tre olika intressenters perspektiv: kommun, bostadsutvecklare och institutionella investerare. Med genomförbarhet menas sannolikheten att ett bostadsutvecklingsprojekt kommer förverkligas med ett lyckat utfall. Genom att undersöka och lyfta fram de tre perspektiven syftar uppsatsen till att åskådliggöra den komplicerade dynamiken mellan dessa intressenter och konsekvenserna av de kommunala hållbarhetskraven på projektens genomförbarhet. Framför allt är målet att synliggöra bostadsutvecklarnas upplevda utmaningar och identifiera potentiella områden för förbättringar kring hur de kommunala kraven kan implementeras. Studien är baserad på en fallstudie av Eindhoven kommun i Nederländerna. Principal-agentteorin används i kombination med en kvalitativ analysmetod för att nå nya insikter om effektiviteten i genomförandet av kommunala hållbarhetskrav, om samspelet mellan de tre intressenterna samt de institutionella investerarnas investeringsstrategier. Studien konkluderar att samarbetet mellan bostadsutvecklare och kommun är avgörande för att övervinna hinder och skapa lyckade bostadsutvecklingsprojekt. Detta är kopplat till att bygga upp förtroende, erkänna varandras intressen och dela risker och ansvar. Att anpassa de politiska kraven till konsumenternas behov, främja förtroende och förståelse mellan intressenterna och skapa någon form av "övergångspolitik" är de viktigaste slutsatserna från studien. Likaså kontinuitet i genomförandet av politiken, som identifieras som en nyckelfaktor för att undvika oväntade kostnader och förseningar i pågående bostadsutvecklingsprojekt. Genom dessa insikter avser studien bidra till ett mer effektivt genomförande av de kommunala hållbarhetskraven, förbättra samarbetet mellan viktiga intressenter och skapa ett mer effektivt bostadsutbud.

Today there is a growing issue of physical inactiveness, especially during the winter period, leading to various health issues. The new-found concept of a Winter Activity Park can be a possible solution for Swedish municipalities, as a means to increase spontaneous physical activity, and improve public health, during the winter season. The concept has originated from the need for increased spontaneous physical activity during winter and includes creating a physical activity facility with the usage of artificial snow. Södertälje is a municipality where a Winter Activity Park could act as a solution in order to increase spontaneous physical activity. The aim of the study is to assess the feasibility of a Winter Activity Park, using artificial snow, in Södertälje municipality. The study sets out to determine what is technically required in order to implement a Winter Activity Park, and by including two specific sites in Södertälje (Stadsparken and Tveta Friluftsgård), it can be assessed how well each site is meeting the requirements. Additionally, the study sets out to assess what possible environmental impacts the implementation may lead to at each site, as well as determining how artificial snow should be obtained to have the least contribution to climate change. The results show that there are several technical requirements that need to be fulfilled at a site in order to implement a Winter Activity Park. Neither of the chosen sites are currently meeting all the technical requirements for a Winter Activity Park, although it is considered possible for both sites to be able to fulfil them at a later stage. By conducting an EIA, it was concluded that Tveta Friluftsgård were likely to experience less negative environmental consequences from the implementation of a Winter Activity Park, compared to Stadsparken. By calculating the carbon footprint for the alternative ways of obtaining artificial snow, it was concluded that producing snow directly at a site, using a lake as a water source, would be the most favourable, in terms of least contribution to climate change. As a final conclusion, it was determined that a Winter Activity Park is feasible in Södertälje municipality, with Tveta Friluftsgård and production directly at the site seemingly being the best way to go. However, depending on what the purpose of the Winter Activity Park is, other sites and methods of obtaining snow can be more suitable. In order to create a more comprehensive view of the feasibility and sustainability of the concept of a Winter Activity Park, future studies should investigate social and economic aspects related to the concept. / Ett växande problem i dagens samhälle är fysisk inaktivitet, främst under vinterhalvåret, vilket leder till flera olika hälsoproblem. Det nyfunna konceptet Vinterparkleken kan vara en möjlig lösning för kommuner i Sverige för att öka spontan fysisk aktivitet under vintersäsongen och därmed förbättra folkhälsan. Konceptet har sitt ursprung från behovet av ökad spontan fysisk aktivitet, och innebär införandet av en anläggning för fysisk aktivitet med användandet av tillverkad snö. Södertälje är en kommun där en Vinterparklek kan vara en möjlig lösning för att öka den spontana fysiska aktiviteten. Syftet med studien är att utvärdera genomförbarheten av Vinterparkleken med konstgjord snö i Södertälje kommun. Studien syftar till att bedöma vad som är tekniskt nödvändigt för att genomföra en Vinterparklek och två specifika platser i Södertälje (Stadsparken och Tveta Friluftsgård) är inkluderade i studien för att bedöma hur väl varje plats uppfyller kraven. Studien syftar även till att bedöma vilka möjliga miljöeffekter implementeringen av en Vinterparklek kan leda till på varje plats, samt bestämma på vilket vis konstgjord snö ska erhållas för att ha minst bidrag till klimatförändring. Resultaten visar att det finns flera tekniska krav som måste uppfyllas på en plats för att kunna genomföra en Vinterparklek. Ingen av de valda platserna uppfyller för närvarande alla tekniska krav för en Vinterparklek, även om det anses möjligt att bägge platserna kommer kunna uppfylla dem i ett senare skede. Resultaten från MKB visade på att införandet av en Vinterparklek vid Tveta Friluftsgård rimligtvis skulle ha mindre negativa miljökonsekvenser jämfört med vid Stadsparken. Genom att beräkna koldioxidavtrycket för de alternativa sätten att erhålla tillverkad snö, drogs slutsatsen att snö producerad direkt på plats, samt använda en sjö som vattenkälla, skulle vara det mest gynnsamma, i form av minst bidrag till klimatförändringar. Den slutliga slutsatsen är att en Vinterparklek är genomförbar i Södertälje kommun, med Tveta Friluftsgård och snötillverkning direkt på plats som till synes bästa tillvägagångssättet. Vilken plats som ska väljas och hur snö ska erhållas kan dock även bestämmas utifrån vad konceptet är menat att bidra med. För att skapa en mer övergripande bild av genomförbarheten och hållbarheten av en Vinterparklek bör framtida studier undersöka sociala och ekonomiska aspekterna som är relaterade till konceptet.

Background: The primary objective of this study was to assess the feasibility of the Healthy Lifestyles Program (HLP), a novel 12-month complex intervention based in cognitive behavioural therapy and theories of behavioural change, delivered in a community-based setting in Hamilton, Canada. The secondary objective was to explore implementation factors. Methods/ design: A pragmatic pilot randomised controlled trial using quantitative and qualitative evaluation methods. Participants were randomly allocated to either intervention group (n=15) or comparator group (n=15). The intervention group attended weekly group education sessions and met in-person with a healthcare team monthly to create personalized health goals and action plans. The comparator group met with a research assistant every three months to develop health goals and action plans. We assessed feasibility of the program by measuring recruitment, participation and retention rates, missing data, and attendance. All participant-directed and clinical outcome measures were analyzed for between and within group changes using Generalized Estimating Equations (GEE). Content analysis was conducted for qualitative data. Results: We recruited and randomized 30 participants to each group (n=15) within 3 months. Retention rate was 60% (9/15) for the intervention group and 47% (7/15) for the comparator group. Less than 1% of participant-directed and clinical outcomes were missing. Participants attended an average of 29 of 43 educational sessions and 100% of one-to-one sessions. The healthcare team valued the program’s holistic approach to care, increased time and interaction with participants, professional collaboration, and the ability to provide counselling and health supports. Location accessibility was an important factor facilitating implementation. Reducing the number of psycho-social education sessions and having access to a gym could improve retention and delivery of the program. Conclusion: This study has demonstrated the feasibility of the HLP with minor modifications recommended for a larger trial and for the intervention. / Thesis / Master of Public Health (MPH) / Rates of chronic physical and mental health illness are rising in Canada. Lifestyle or behavioural changes can prevent or manage chronic diseases. The aim of this pilot study is to test the feasibility of delivering a 12-month Healthy Lifestyles Program to participants in Hamilton, Canada. The Healthy Lifestyles Program is a complex intervention designed to help participants identify health goals and action plans to achieve those goals with the guidance of healthcare professionals. We observed that the program was successfully delivered, accepted by participants and staff and required minor changes to the study design for a scaled-up study. The program showed positive trends for improving goal attainment, depression, and loneliness scores. The results of this study will help inform the design and scale-up of a larger study.

A method for performing robust optimal design that combines the efficiency of experimental designs and the accuracy of nonlinear programming (NLP) has been developed, called Search-and-Zoom. Two case studies from the RF and communications industry, a high-frequency micro-strip band-pass filter (BPF) and a rectangular, directional patch antenna, were used to show that sensitivity optimization could be effectively performed in this industry and to compare the computational efficiency of traditional NLP methods (using fmincon solver in MATLAB R2013a) and they hybrid method Search-and-Zoom. The sensitivity of the BPF's S11 response was reduced from 0.06666 at the (non-robust) nominal optimum to 0.01862 at the sensitivity optimum. Feasibility in the design was improved by reducing the likelihood of violating constraints from 20% to nearly 0%, assuming RSS (i.e., normally-distributed) input tolerances and from 40% to nearly 0%, assuming WC (i.e., uniformly-distributed) input tolerances. The sensitivity of the patch antenna's S11 function was also improved from 0.02068 at the nominal optimum to 0.0116 at the sensitivity optimum. Feasibility at the sensitivity optimum was estimated to be 100%, and thus did not need to be improved. In both cases, the computation effort to reach the sensitivity optima, as well as the sensitivity optima with RSS and WC feasibility robustness, was reduced by more than 80% (average) by using Search-and-Zoom, compared to the NLP solver.

Today, Real World Data (RWD) is a popular topic in many studies. In particular, it is anticipated to be a significant resource for addressing issues brought on by drug development costs, lengthy development times, and safety concerns. The Swedish healthcare Quality Registries (QR) are studied to contribute to the improvement of health care with individual-based clinical data. Recorded data is used for quality improvement, guidance compliance monitoring, and research. However, the workflow for such a framework that applies RWD which is patient-related data that came from various sources to the new drug development field is currently not well-defined. Thus the main aim of this project is to establish a strategy for integrating RWD with pharmaceutical modeling. To achieve this aim, QRs were examined through an ontological approach. The data and procedures necessary for modeling the development of new drugs, as well as the correspondence of the pieces offered by QR, were studied to assess the feasibility. The modeling of new drug development was studied for three applications: Adverse Drug Event (ADE), Computer-based Simulation (CBS), and drug repurposing, and the analysis of QRs was conducted on seven diseases. After in-depth analysis, although there were differences between the registries, it showed enough feasibility in terms of how much the data provided in the studies on drug repurposing and computer-based simulation satisfied the items required for new drug development. However, in the case of rare diseases, given the lack of an automated method, the ethical ambiguity, and the speed of the process, there still seems to be potential for improvement.  Many registries have begun to support research on the development of novel medications, such as by independently recording the features of drugs. These initiatives could enable the future potential of new Real World Evidence (RWE) such as in the field of proteomics and genomics discovery. / Idag är Real World Data (RWD) ett populärt ämne i många studier. I synnerhet förväntas det vara en betydande resurs för att ta itu med problem som orsakas av kostnader för läkemedelsutveckling, långa utvecklingstider och säkerhetsproblem. Kvalitetsregistren studeras för att bidra till att förbättra hälso- och sjukvården med individbaserade kliniska data. Registrerade data används för kvalitetsförbättring, övervakning av efterlevnad av riktlinjer och forskning. Arbetsflödet för ett sådant ramverk som tillämpar RWD som är patientrelaterad data som kom från olika källor till det nya läkemedelsutvecklingsområdet är dock för närvarande inte väldefinierat. Därför är huvudsyftet med detta projekt att upprätta en strategi för att integrera RWD med läkemedelsmodellering. För att uppnå detta mål undersöktes kvalitetsregister genom ett ontologiskt tillvägagångssätt. De data och procedurer som krävs för att modellera utvecklingen av nya läkemedel, såväl som överensstämmelsen mellan de bitar som erbjuds av kvalitetsregister, studerades för att bedöma genomförbarheten. Modelleringen av utvecklingen av nya läkemedel studerades för tre tillämpningar: skadlig läkemedelseffekt, datorbaserad simulering och återanvändning av läkemedel, och analys av kvalitetsregister genomfördes på sju sjukdomar. Efter en djupgående analys, även om det fanns skillnader mellan registren, visade den tillräcklig genomförbarhet när det gäller hur mycket data som tillhandahållits i studierna om läkemedelsåteranvändning och datorbaserad simulering uppfyllde de krav som krävdes för utveckling av nya läkemedel. Men när det gäller sällsynta sjukdomar, med tanke på avsaknaden av en automatiserad metod, den etiska oklarheten och processens snabbhet, verkar det fortfarande finnas potential för förbättringar. Många register har börjat stödja forskning om utveckling av nya mediciner, till exempel genom att oberoende registrera drogens egenskaper. Dessa initiative skulle kunna möjliggöra den framtida potentialen för nya verkliga bevis, såsom inom området för proteomik och genomik.

Concurrent Design studies have become of great importance in the space industry reducing the time and costs associated to the feasibility assessments for future space missions. This has also helped companies and space agencies to be at the forefront of this fast-developing sector. These collaborative sessions are carried out by an interdisciplinary group of engineers, experts and customers who are capable of achieving an optimal design solution within a short period of time, typically a few weeks. They make use of dedicated tools, like COMET® which is developed by RHEA Group, to store and share the data within the team, as well as with other partners or stakeholders. As new software tools are developed for Model-Based Systems Engineering (MBSE) applications, parallel improvements are needed for Concurrent Engineering teams, since this can be one of the first steps for a model-based approach. One of the main constraints during Concurrent Design studies is the limited number of analysed options, since evaluating the entire design space would require longer sessions and increased time availability from the experts, and would consequently result in more expensive projects. One solution for this problem can be the application of generative engineering technologies to Concurrent Design studies. This method would allow to explore the entire design space by first defining the study model together with the system constraints, and then using a software to automatically generate all the possible architecture variants for that specific model. An example of state-of-the-art technologies for generative design is Simcenter™ Studio, a recently released tool from Siemens Digital Industries Software. The complexity of space missions requires a very detailed definition and evaluation of the system architecture, even at the early stages of the design process. Therefore, research is needed on the use and implementation of new methodologies that will tackle the challenges related to Concurrent Design. The context of the research presented in this thesis is the new project proposed by RHEA Group, Siemens and OHB, called Generative Concurrent Design (GCD). It aims to combine their software tools COMET® and Simcenter Studio, bringing generative engineering to Concurrent Design. One of the main advantages is achieving more optimised solutions in shorter times, reducing the number of necessary iterations on the system architecture during the entire project lifecycle. An enhanced feature of this tool is the possibility for the users to explore the solutions trade space with the support of an Artificial Intelligence (AI) based system. This thesis presents and demonstrates the application of the GCD methodology to a use case at system level, focused on the evaluation of configuration and assembly options in the design of a spacecraft. Using the mission EnVision, selected in 2021 by ESA’s Science Programme Committee, as the design baseline, the GCD methodology has been implemented in this use case study making use of both software tools and showing potential future features and applications. / Les études de conception concourante ont pris une grande importance dans l'industrie spatiale, en réduisant le temps et les coûts associés aux évaluations de faisabilité des futures missions spatiales. Cela a également permis aux entreprises et aux agences spatiales d'être à l'avant-garde de ce secteur en plein essor. Ces sessions de collaboration sont menées par un groupe interdisciplinaire d'ingénieurs, d'experts et de clients qui sont capables d'obtenir une solution de conception optimale dans un délai court, généralement quelques semaines. Ils utilisent des outils dédiés, comme COMET® qui est développé par RHEA Group, pour stocker et partager les données au sein de l'équipe, ainsi qu'avec d'autres partenaires ou parties prenantes. Au fur et à mesure que de nouveaux outils logiciels sont développés pour les applications d'ingénierie des systèmes basés sur les modèles (MBSE), des améliorations parallèles sont nécessaires pour les équipes d'ingénierie concourante, car cela peut constituer l'une des premières étapes d'une approche basée sur les modèles. L'une des principales contraintes lors des études de conception concourante est le nombre limité d'options analysées, car l'évaluation de l'ensemble de l'espace de conception nécessiterait des sessions plus longues et une plus grande disponibilité des experts, ce qui se traduirait par des projets plus coûteux.  Une solution à ce problème pourrait être l'application des technologies d'ingénierie générative aux études de conception concourante. Cette méthode permettrait d'explorer l'ensemble de l'espace de conception en définissant d'abord le modèle d'étude ainsi que les contraintes du système, puis en utilisant un logiciel pour générer automatiquement toutes les variantes possibles du système pour ce modèle spécifique. Un exemple de technologies de pointe pour la conception générative est Simcenter™ Studio, un outil récemment publié par Siemens Digital Industries Software.  La complexité des missions spatiales exige une définition et une évaluation très détaillées de l'architecture du système, même aux premiers stades du processus de conception. Par conséquent, des recherches sont nécessaires sur l'utilisation et la mise en œuvre de nouvelles méthodologies qui permettront de relever les défis liés à la conception concourante. Le contexte de la recherche présentée dans cette thèse est le nouveau projet proposé par RHEA Group, Siemens et OHB, appelé Conception Concurrente Générative (Generative Concurrent Design ou GCD en anglais). Il vise à combiner leurs outils logiciels COMET® et Simcenter Studio, en apportant l'ingénierie générative à la conception concourante. L'un des principaux avantages est de parvenir à des solutions plus optimisées dans des délais plus courts, en réduisant le nombre d'itérations nécessaires sur l'architecture du système pendant tout le cycle de vie du projet. Une caractéristique améliorée de cet outil est la possibilité, pour les utilisateurs, d'explorer l'espace commercial des solutions avec le soutien d'un système basé sur l'intelligence artificielle (IA). Cette thèse présente et démontre l'application de la méthodologie GCD à un cas d'utilisation au niveau système, centré sur l'évaluation des options de configuration et d'assemblage dans la conception d'un vaisseau spatial. En utilisant la mission EnVision, sélectionnée en 2021 par le Comité du Programme Scientifique de l'ESA, comme base de conception, la méthodologie GCD a été mise en œuvre dans cette étude de cas d'utilisation, en employant les deux outils logiciels et en montrant les fonctionnalités et applications potentielles futures.