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401	Item Response Theory in the Neurodegenerative Disease Data Analysis / Théorie de la réponse d'item dans l'analyse des données sur les maladies neurodégénératives Wang, Wenjia 21 June 2017 (has links) Les maladies neurodégénératives, telles que la maladie d'Alzheimer (AD) et Charcot Marie Tooth (CMT), sont des maladies complexes. Leurs mécanismes pathologiques ne sont toujours pas bien compris et les progrès dans la recherche et le développement de nouvelles thérapies potentielles modifiant la maladie sont lents. Les données catégorielles, comme les échelles de notation et les données sur les études d'association génomique (GWAS), sont largement utilisées dans les maladies neurodégénératives dans le diagnostic, la prédiction et le suivi de la progression. Il est important de comprendre et d'interpréter ces données correctement si nous voulons améliorer la recherche sur les maladies neurodégénératives. Le but de cette thèse est d'utiliser la théorie psychométrique moderne: théorie de la réponse d’item pour analyser ces données catégoriques afin de mieux comprendre les maladies neurodégénératives et de faciliter la recherche de médicaments correspondante. Tout d'abord, nous avons appliqué l'analyse de Rasch afin d'évaluer la validité du score de neuropathie Charcot-Marie-Tooth (CMTNS), un critère important d'évaluation principal pour les essais cliniques de la maladie de CMT. Nous avons ensuite adapté le modèle Rasch à l'analyse des associations génétiques pour identifier les gènes associés à la maladie d'Alzheimer. Cette méthode résume les génotypes catégoriques de plusieurs marqueurs génétiques tels que les polymorphisme nucléotidique (SNPs) en un seul score génétique. Enfin, nous avons calculé l'information mutuelle basée sur la théorie de réponse d’item pour sélectionner les items sensibles dans ADAS-cog, une mesure de fonctionnement cognitif la plus utilisées dans les études de la maladie d'Alzheimer, afin de mieux évaluer le progrès de la maladie. / Neurodegenerative diseases, such as Alzheimer’s disease (AD) and Charcot Marie Tooth (CMT), are complex diseases. Their pathological mechanisms are still not well understood, and the progress in the research and development of new potential disease-modifying therapies is slow. Categorical data like rating scales and Genome-Wide Association Studies (GWAS) data are widely utilized in the neurodegenerative diseases in the diagnosis, prediction and progression monitor. It is important to understand and interpret these data correctly if we want to improve the disease research. The purpose of this thesis is to use the modern psychometric Item Response Theory to analyze these categorical data for better understanding the neurodegenerative diseases and facilitating the corresponding drug research. First, we applied the Rasch analysis in order to assess the validity of the Charcot-Marie-Tooth Neuropathy Score (CMTNS), a main endpoint for the CMT disease clinical trials. We then adapted the Rasch model to the analysis of genetic associations and used to identify genes associated with Alzheimer’s disease by summarizing the categorical genotypes of several genetic markers such as Single Nucleotide Polymorphisms (SNPs) into one genetic score. Finally, to select sensitive items in the most used psychometrical tests for Alzheimer’s disease, we calculated the mutual information based on the item response model to evaluate the sensitivity of each item on the ADAS-cog scale. Maladie neurodegenerative Echelle de notation Données categoriques Theorie de la réponse d’item Modèle Rasch Analyse Rasch GWAS Test d’association génétique Maladie d’Alzheimer Maladie Charcot-Marie-Tooth CMTNS Information mutuelle ADAS-cog Neurodegenerative disease Rating scale Categorical data Item response theory Rasch Model Rasch analysis GWAS Gene-based association test Alzheimer’s disease Charcot-Marie-Tooth disease CMTNS Mutual information ADAS-cog
402	MODELAGEM DE DIMENSÕES DA QUALIDADE DE APARTAMENTOS VIA TEORIA DE RESPOSTA AO ITEM E TEORIA CLÁSSICA DE TESTES / QUALITY DIMENSIONS MODELING OF APARTMENTS VIA ITEM RESPONSE THEORY AND CLASSICAL TEST THEORY Schrippe, Patrícia 09 February 2015 (has links) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / This dissertation aims to analyze the items and dimensions of quality related to apartments in the city of Santa Maria / RS. It is underlined that quality investigated comes to compliance with the characteristics required by customers. About the methodological proceedings, 39 characteristics of location qualities, position and typological were listed according to the bibliography and sequentially reviewed by the real estate agencies. Subsequently, on the real estate agencies, data were collected of 500 apartments sold on 04/01/2013 to 08/25/2014; representing 37% of apartments sold in the city in that period. The data analysis began with the classical theory of tests, using Exploratory Factor Analysis and Confirmatory Factor Analysis sequentially, using the varimax rotation; which identified two factors, based on the criterion of Kaiser. Thus, the approach of Item Response Theory was opportunity, with the logistic model of two parameters as well, the presentation of the critical aspects on the use of Item Response Theory. The first model of Item Response Theory, whose latent trait was named quality of apartments about status, are compost of four items; while the second model, the latent trait quality of apartments about utility, no identified items Sequentially, it was found that the analyzed apartments had scores between 80 to 90, thus, it is clear that most of the apartments investigated for status have the score features 80 in ITR. Therefore it is possible conclude that the proposed objective of this dissertation was achieved. / Esta dissertação visa analisar os itens e dimensões da qualidade referentes aos apartamentos da cidade de Santa Maria/RS. Salienta-se que a qualidade estudada se trata da satisfação das características requeridas pelos clientes. Acerca dos procedimentos metodológicos, 39 características acerca de qualidades de localização, posição e tipológicas foram elencados de acordo com a bibliografia e sequencialmente verificados nas agências imobiliárias. Posteriormente, nas agências imobiliárias, foram coletados dados de 500 apartamentos vendidos nos períodos de 04/01/2013 a 25/08/2014; representando 37% dos apartamentos vendidos na cidade no referido período. O tratamento dos dados iniciou com a Teoria Clássica dos Testes, utilizando a Análise Fatorial Exploratória e sequencialmente a Análise Fatorial Confirmatória, utilizando a rotação ortogonal varimax; que apontou dois fatores, tendo como base o critério de Kaiser. Oportunizando assim a abordagem da Teoria de Resposta ao Item, apresentando o Modelo Logístico de dois parâmetros bem como, a apresentação dos aspectos críticos acerca da utilização da Teoria de Resposta ao Item. O primeiro modelo da Teoria de Resposta ao Item, cujo traço latente foi denominado qualidade dos apartamentos quanto ao status do apartamento, é composto por quatro itens; enquanto o segundo modelo, de traço latente qualidade dos apartamentos quanto à utilidade, não gerou itens. Sequencialmente, verificou-se que os apartamentos analisados possuíam escore entre 80 a 90, por conseguinte, é possível afirmar que a maioria dos apartamentos investigados quanto a status possuem as características de escore 80 na TRI. Portanto, é possível afirmar que, o objetivo proposto da presente dissertação foi alcançado. Mercado Imobiliário Imóveis urbanos Apartamentos Psicometria Teoria de Resposta ao Item Modelo Logístico de dois parâmetros Teoria Clássica de Testes Correlação de Pearson Real Estate Market Urban real estate Apartments Psychometrics Item Response Theory Logistic model of two parameters Classical Test Theory Pearson Correlation
403	Avaliação educacional : um olhar matemático Fugita, Felipe January 2018 (has links) Orientador: Prof. Dr. Daniel Miranda Machado / Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Mestrado Profissional em Matemática em Rede Nacional - PROFMAT, Santo André, 2017. / Um dos objetivos desse trabalho é explicar a Teoria de Resposta ao Item, conhecida como TRI, enfatizando o modelo logístico de três parâmetros e descrevendo suas principais características. Outro objetivo é mostrar como o professor pode utilizar ferramentas estatísticas, em uma planilha eletrônica, para: verificar a qualidade das questões que compõe sua prova; analisar se existe uma correlação entre dois instrumentos de avaliação; utilizar a média escolar de um aluno para inferir sobre o seu desempenho no vestibular; entre outras possibilidades. Com a finalidade de explicar a TRI e seu método de estimação de parâmetros por Máxima Verossimilhança, são apresentados previamente os modelos Matemáticos, Probabilísticos e Estatísticos, pilares dessa teoria. Além disso, é descrito como os programas de avaliações educacionais em larga escala de diversos países utilizam a TRI para monitorar o desempenho de seus sistemas educacionais. Em seguida, são expostas algumas ferramentas Estatísticas, em específico, o coeficiente de correlação, o método de mínimos quadrados e o ponto bisserial que podem colaborar nos processos de avaliações educacionais que fazem parte da rotina escolar. São ilustrados também exemplos de planilhas eletrônicas com a descrição passo a passo de sua construção e dos comandos utilizados. Desse modo, espera-se contribuir para compreensão da TRI e, consequentemente, dos indicativos educacionais produzidos pelos programas de avaliações em larga escala, bem como, para atuação e reflexão da prática docente em seus métodos de avaliação educacional. / One of the goals of this work is to explain Item Response Theory, known as IRT, emphasizing the Three-Parameter Logistic model and describing its main characteristics. Another objective is to demonstrate how educators can use statistical tools within a spreadsheet to: verify the quality and reliability of test questions; examine whether there is a correlation between two assessment tools; use the school average of a student to predict his or her performance in entrance examinations; among other possibilities. To explain IRT and its method of parameter estimation by maximum likelihood, this work presents the mathematical, probabilistic and statistical models that are the pillars of the theory. It also describes how the large-scale educational assessment programs of various countries use IRT to monitor the performance of their education systems. Then, this work presents a selection of statistical tools, specifically, the correlation coefficient, the least squares method and the point biserial correlation, which could contribute to the process of routine educational assessments. Also provided are illustrated examples of spreadsheets with step-by- step descriptions of their creation and the commands used. Thus, the work hopes to contribute to the understanding of IRT and, consequently, of the educational indicators produced by large-scale assessment programs, as well as benefit educators in their practice and reflection on methods of educational evaluation. TEORIA DE RESPOSTA AO ITEM AVALIAÇÃO DA EDUCAÇÃO PROBABILIDADE ESTATÍSTICA CORRELAÇÃO MÉTODO DE MÍNIMOS QUADRADOS PONTO BISSERIAL ESTIMATIVA DE MÁXIMA VEROSSIMILHANÇA ITEM RESPONSE THEORY EDUCATIONAL EVALUATION CORRELATION LEAST SQUARE METHODS POINT-BISERIAL
404	Construction et validation d’une échelle de mesure de la coercition sexuelle Raiche, Ann-Pierre 08 1900 (has links) Contexte. Au cours des dernières années, l’évaluation de la violence sexuelle a connu un essor croissant. En effet, les milieux de la recherche tentent d’étudier plus largement l’ensemble des violences sexuelles, notamment en s’intéressant à la coercition sexuelle. À ce jour, il subsiste des différences quant à la définition de la notion de coercition sexuelle et une incertitude relative aux instruments de mesure à employer demeure. Objectif. L’objectif du présent mémoire est donc de construire et de mettre à l’épreuve la validé d’une échelle de mesure de la coercition sexuelle en utilisant les items du Multidimensional Inventory of Development, Sex, and Agression (MIDSA). Méthodes. L’échantillon est composé de 529 hommes, ayant commis une infraction à caractère sexuel, incarcérés dans une prison ou encore dans un centre de traitement du Massachusetts ou du Minnesota. Tous les participants ont complété le MIDSA. Le MIDSA propose 20 items mesurant 5 types de tactiques de coercition sexuelle : la manipulation, l’intoxication volontaire, l’action de prendre avantage d’une personne intoxiquée, la menace de l’utilisation de la force physique ainsi que l’utilisation de la force physique. Résultats. Les résultats indiquent que l’échelle de coercition sexuelle à 5 items possède les meilleures propriétés psychométriques. La cohérence interne de l'échelle est bonne. De plus, les analyses de théorie de réponse à l’item indiquent que la majorité des items étaient considérés comme difficiles et que tous les items possèdent un bon pouvoir discriminant. Enfin, l’échelle présente des corrélations de modérées à élevées avec la majorité des échelles associées, indiquant ainsi une bonne validité convergente et concurrente. / Background. In recent years, the assessment of sexual violence has grown steadily. In fact, the research community has been trying to examine broader forms of sexual perpetration and victimization, especially sexual coercion. There is no consistent definition in the literature for sexual coercion and uncertainty remains regarding the measuring instruments. Objective. The study aims to create a scale of sexual coercion using items from the Multidimensional Inventory of Development, Sex, and Aggression (MIDSA) and assess its validity. Methods. The sample included 529 adult males who committed a sexual offense. They completed the MIDSA while incarcerated in prisons and special commitment facilities in Massachusetts and Minnesota at the time of assessment. The MIDSA proposes a 20 item pool measuring sexual coercion based on 5 types of tactics to coerce someone into sexual activity: manipulation and bribing, offering drinks or drugs, taking advantage of someone already intoxicated by drugs or alcohol, using threats of physical force, and the use of physical force. Results. Findings from this study revealed that a 5-item version of the sexual coercion scale has the best psychometric properties. The internal consistency of the scale is good. Furthermore, the item response theory analysis shows that most items were considered difficult and serious and that all items present a good discriminant power. Finally, the sexual coercion scale presents moderate-high correlations with almost all associated scales, indicating good convergent and concurrent validity. Violence sexuelle Coercition sexuelle Définitions Mesures psychométriques Échelle de mesure Théorie Classique des Tests Théorie de Réponse à l’Item Validité convergente Validité concurrente Sexual violence Sexual coercion Definitions Psychometric measures Scale Classical Test Theory Item Response Theory Convergent validity Concurrent validity
405	Happiness at work: are job satisfaction, job self-efficacy and trait emotional intelligence related? De Kok, Caitlin Anne 01 1900 (has links) This thesis explores and describes the relationship between emotional intelligence, job satisfaction and job self-efficacy. The sample was collected between 2007 and 2010 and consists of 1336 South Africans within the workplace. Trait emotional intelligence was assessed using the Trait Emotional Intelligence Questionnaire (TEIQue), while job satisfaction and job self-efficacy were assessed from the biographical questions asked during the TEIQue assessment process. The first hypothesis investigated whether there is a statistically significant relationship between job satisfaction and trait emotional intelligence. A relationship was found that is statistically, but not practically, significant. The second hypothesis centred on the relationship between job self-efficacy and emotional intelligence, with statistically significant results (p<0.001), and a weaker relationship than the one found between job satisfaction and scores on the TEIQue. The third hypothesis, investigating a possible interaction effect between job satisfaction and job self-efficacy, was rejected. In addition to the study’s three hypotheses, exploratory IRT analysis was conducted on a section of the TEIQue items in order to further explore the functioning of the test within the South African context. Findings suggest that there is a relationship between the constructs within the study, but that this relationship is more complex than first assumed, being affected by issues such as social desirability and central tendency bias. / Psychology / M.A. (Psychology) Emotional intelligence Trait emotional intelligence Job satisfaction Job self-efficacy Item response theory General (graded) response model Analysis of variance Workplace Self-efficacy 158.7 Attitude (Psychology) -- Testing Trait intercorrelations Job satisfaction -- Research Emotional intelligence -- Research Work -- Psychological aspects Success -- Psychological aspects Emotional intelligence tests --Research Self efficacy -- Research
406	A Psychometric Evaluation of Script Concordance Tests for Measuring Clinical Reasoning Wilson, Adam Benjamin 29 January 2014 (has links) Indiana University-Purdue University Indianapolis (IUPUI) / Purpose: Script concordance tests (SCTs) are assessments purported to measure clinical data interpretation. The aims of this research were to (1) test the psychometric properties of SCT items, (2) directly examine the construct validity of SCTs, and (3) explore the concurrent validity of six SCT scoring methods while also considering validity at the item difficulty and item type levels. Methods: SCT scores from a problem solving SCT (SCT-PS; n=522) and emergency medicine SCT (SCT-EM; n=1040) were used to investigate the aims of this research. An item analysis was conducted to optimize the SCT datasets, to categorize items into levels of difficulty and type, and to test for gender biases. A confirmatory factor analysis tested whether SCT scores conformed to a theorized unidimensional factor structure. Exploratory factor analyses examined the effects of six SCT scoring methods on construct validity. The concurrent validity of each scoring method was also tested via a one-way multivariate analysis of variance (MANOVA) and Pearson’s product moment correlations. Repeated measures analysis of variance (ANOVA) and one-way ANOVA tested the discriminatory power of the SCTs according to item difficulty and type. Results: Item analysis identified no gender biases. A combination of moderate model-fit indices and poor factor loadings from the confirmatory factor analysis suggested that the SCTs under investigation did not conform to a unidimensional factor structure. Exploratory factor analyses of six different scoring methods repeatedly revealed weak factor loadings, and extracted factors consistently explained only a small portion of the total variance. Results of the concurrent validity study showed that all six scoring methods discriminated between medical training levels in spite of lower reliability coefficients on 3-point scoring methods. In addition, examinees as MS4s significantly (p<0.001) outperformed their MS2 SCT scores in all difficulty categories. Cross-sectional analysis of SCT-EM data reported significant differences (p<0.001) between experienced EM physicians, EM residents, and MS4s at each level of difficulty. When considering item type, diagnostic and therapeutic items differentiated between all three training levels, while investigational items could not readily distinguish between MS4s and EM residents. Conclusions: The results of this research contest the assertion that SCTs measure a single common construct. These findings raise questions about the latent constructs measured by SCTs and challenge the overall utility of SCT scores. The outcomes of the concurrent validity study provide evidence that multiple scoring methods reasonably differentiate between medical training levels. Concurrent validity was also observed when considering item difficulty and item type. psychometrics script concordance test factor analysis clinical reasoning Analysis of variance Multivariate analysis Medical logic -- Measurement Examinations -- Design and construction Uncertainty Sex role -- Research -- Methodology Cognitive learning theory Cognitive psychology -- Research
407	Optimierung von Messinstrumenten im Large-scale Assessment Hecht, Martin 21 July 2015 (has links) Messinstrumente stellen in der wissenschaftlichen Forschung ein wesentliches Element zur Erkenntnisgewinnung dar. Das Besondere an Messinstrumenten im Large-scale Assessment in der Bildungsforschung ist, dass diese normalerweise für jede Studie neu konstruiert werden und dass die Testteilnehmer verschiedene Versionen des Tests bekommen. Hierbei ergeben sich potentielle Gefahren für die Akkuratheit und Validität der Messung. Um solche Gefahren zu minimieren, sollten (a) die Ursachen für Verzerrungen der Messung und (b) mögliche Strategien zur Optimierung der Messinstrumente eruiert werden. Deshalb wird in der vorliegenden Dissertation spezifischen Fragestellungen im Rahmen dieser beiden Forschungsanliegen nachgegangen. / Measurement instruments are essential elements in the acquisition of knowledge in scientific research. Special features of measurement instruments in large-scale assessments of student achievement are their frequent reconstruction and the usage of different test versions. Here, threats for the accuracy and validity of the measurement may emerge. To minimize such threats, (a) sources for potential bias of measurement and (b) strategies to optimize measuring instruments should be explored. Therefore, the present dissertation investigates several specific topics within these two research areas. Psychologie Bildungsforschung Optimierung Kontexteffekte Bearbeitungszeit Blockpaarbalance Designeffekte Designbalancierung Generalisierte lineare Mischmodelle IQB IRT Lineare Mischmodelle Messmodell Messinstrument Multi-Matrix Design Parameterschätzung Parameterverzerrung Positionsbalance Rasch-Modell Testhefteffekte Testheftschwierigkeit Testheftleichtigkeit Testdesign Unvollständige Blockdesigns Positionseffekte Schulleistungsstudien context effects optimization linear mixed models generalized linear mixed models response time educational assessment cluster pair balance design effects design balance item response theory measurement model measurement instrument parameter estimation parameter bias position balance psychology Rasch model 1PL model booklet effects booklet difficulty booklet easiness test design booklet design incomplete block design multiple matrix sampling position effects large-scale assessment 150 Psychologie 11 Psychologie CM 3000 CM 3200 ddc:150

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