This thesis focuses on the important private law institute of preliminary injunctions used for the provisional regulation of the circumstances of minors. The fundamental legal principle on which the paper is based is the principle of the best interests of the child, largely based on Art. 3 of the Convention on the Rights of the Child, which states that the best interests of the child shall be a primary consideration in any decision-making concerning children. Emphasis is placed on the child's legal status as a party to the proceedings for a preliminary injunction and the consequent rights of the minor, focusing on the child's right to be heard. The individual chapters are devoted to a detailed analysis of Czech legislation relating to the topic in question, both under the current wording of the law and current application in practice. The first chapter offers a concise introduction to the addressed issue. The second chapter provides definitions of the key concepts related to the topic. The third chapter discusses the position of the child as a party to the proceedings for the issue of a preliminary injunction, their procedural personality and procedural capacity, representation of the child in the process itself and, last but not least, the interests of the child, and their fundamental rights to be...

This thesis examines the use and interpretation of Revelation in the writings of the contemporary prophets Richard Brothers, Joanna Southcott and William Blake. Contributing to an emerging scholarly interest in the reception of biblical texts within marginalised interpretative traditions, the thesis offers a detailed exploration of how Revelation is incorporated into these authors' prophetic texts, and how it informs the identity of readers who see their activities as bringing about the fulfilment of the text's visions on the historical plane. This aim is achieved by engaging with extant comparative studies of Brothers, Southcott and Blake within historical and literary studies; a comparison with similar contemporary prophetic figures and the contribution of Revelation to their prophetic self-understandings; and contextualising these figures against contemporary constructions of Revelation as a prophetic text, and the recognition of the poetic nature of biblical prophecy in the eighteenth century. In particular, the thesis advocates for the continued exploration of "emic" approaches to these figures, a process started by members of Oxford's Prophecy Project. The thesis thus argues that "prophecy", rather than "millenarianism," is the most appropriate way of characterising these authors' scriptural engagement, and explores how prophecy is understood in their writings to delineate commonalities in their understanding of the prophet's role. Finally, it surveys how Revelation is interpreted within the respective works of the writers who are the focus of this thesis. The conclusion offers a hermeneutical reflection on the relationship between the prophetic interpreter and the texts they engage with. It suggests that the reader who claims to be "inspired" faces a tension between offering an interpretation of the authoritative text, and claiming an equivalent level of authority for their own works. The thesis makes three contributions to existing scholarly debates. Firstly, it demonstrates that attention to these three authors' interpretations of Revelation shows how attention to neglected voices illuminates the history of interpretation of this biblical book. Secondly, it justifies comparing these three authors under the framework of "prophecy", rather than the anachronistic terminology of "millenarianism." Thirdly, it explores their readings of Revelation to shed light on how interpretation of a scriptural text such as Revelation is key to the evolution of prophetic vocation; how Revelation’s images are developed and transformed in their own prophetic texts; and finally, their sensitivity to hermeneutical questions raised by Revelation’s relationship to other biblical texts and the problems posed by its eschatology.

Ce mémoire de maîtrise propose des outils d’analyse permettant de souligner la cohérence harmonique du langage de Franz Schubert, en particulier dans les œuvres tardives de sa production. L’analyse d’un corpus incluant principalement sa musique de chambre, ses sonates pour piano et une sélection de lieder, nous a permis d’observer des constantes dans le discours harmonique du compositeur. Confrontée à la fois à la richesse de l’écriture tonale de Schubert et aux limites d’un mémoire de maîtrise, nous avons été amenée à concentrer notre étude sur deux traits caractéristiques de son style harmonique, soit le majeur-mineur et sa pratique modulatoire. D’une part, la typologie des emplois du majeur-mineur développée dans ce travail permet de préciser la nature des différents phénomènes s’y rapportant, tout en soulignant l’importance structurelle qu’ils occupent au sein de la forme. Ainsi, nous avons identifié trois types d’emploi de l’interchangeabilité des modes majeur et mineur : l’ornementation à l’intérieur d’un accord (coloration), l’emprunt d’accords au mode opposé à l’intérieur d’une unité structurelle harmonique (mode mixte), et le changement de modes entre deux unités structurelles harmoniques successives (opposition de modes). D’autre part, les mécanismes modulatoires expliqués dans ce mémoire, soit l’emploi du majeur-mineur lors de l’accord pivot, l’altération de la fonction VII ainsi que l’utilisation de dominantes contrariées, entraînent un accroissement de la tension tonale en reliant des zones très éloignées entre elles et agissent comme marqueurs formels dans les œuvres du compositeur. Les mécanismes présentés dans ce mémoire permettent ainsi de préciser la logique harmonique qui sous-tend les œuvres de Schubert, en mettant en valeur l’interaction entre la microstructure et la macrostructure. / This master’s thesis provides analysis tools to highlight the internal consistency of Schubert’s harmonic language, especially in his late works. The analysis of a corpus including mainly his chamber music, his piano sonatas, and a selection of lieder, reveals some constants in the composer’s harmonic organization. Confronted with both the richness of Schubert’s tonal writing and the limits of a master’s thesis, I have chosen two characteristic features of his harmonic style for study : his use of major-minor harmonies and his modulatory practice. First, the typology of the major-minor usages developed in this thesis allows for the specification of the nature of different phenomena related to them, while emphasizing their structural importance in the form. Thus, three types of application of the interchangeability of major and minor modes are identified: ornamentation within a chord (colouration), borrowing of chords from the opposite mode inside a harmonic structural unit (modal mixture), and modal shift between two successive harmonic structural units (mode opposition). Furthermore, the modulatory mechanisms explained in this thesis including the use of major-minor at pivot chords, chromatically altered VII chords, as well as the use of what Serge Gut identifies as « dominantes contrariées » cause an increase in tonal tension by linking remote tonalities and act as formal markers in the works of Schubert. The mechanisms presented in this thesis advance our understanding of the harmonic logic that underlies Schubert’s works by drawing attention to the interaction between microstructure and macrostructure.

There is a constant struggle to increase the efficiency in gas turbines, where one method is to have a higher inlet temperature to the turbine. Often, this results in temperatures higher than the critical temperature of the materials, which makes cooling of the components an important part of the turbine. The cooling air is tapped from the compressor, and has hence required work while being compressed, but since it is removed from the thermodynamic cycle it will not provide any work in the turbine stages. Therefore, it is important to understand the losses in the cooling system to be able to use the smallest amount of cooling air possible, while still cool sufficiently to not decrease the turbine’s lifetime. The pressure losses in the cooling and secondary air systems are due to either friction or minor losses; contractions, expansions and bends. The losses can be described by a discharge coefficient, ; a rate of how close the actual mass flow is to the ideal mass flow, or a pressure loss coefficient, ; a rate of the pressure drop. In the cooling and secondary air systems there are orifices and cooling geometries. These can have different geometrical properties depending on application, and thereby have different heat transfer performances and causing a higher or lower pressure drop. At Siemens Industrial Turbomachinery AB, SIT AB, a one-dimensional in-house program named C3D is used for thermal calculations and calculations of flow properties of internal cooling flow networks. The program uses hydraulic networks consisting of nodes and branches to simulate the flow inside the components. Correlations used for describing pressure losses have been collected and divided depending on their valid ranges, with the aim to make pressure loss calculations easier. A MATLAB code have been developed, which, depending on input parameters, separates the correlations and returns a plot with the correlations that can be used. In order to make the code as useful as possible, a few assumptions were made; curve fitting of correlations which were only available as plots and interpolation to get larger valid ranges for some cases. These assumptions will influence the results, but the code will still be able to give an indication of which correlation to use, and hence, the objective is fulfilled. Simulations in one dimension are commonly used, since it is less time consuming than three-dimensional modelling. Therefore, with focus on the pressure losses, a one-dimensional model of a blade in the in-house program C3D has been evaluated using a three-dimensional model in the CFD program Ansys CFX. Also, two new models were created in C3D; both with geometrical properties and pressure loss coefficients adjusted to the CFX model, but the first model is using the same hydraulic network as in the evaluated, reference, model while the second is using a new network, built according to the streamlines in CFX. The resulting mass flows in the C3D models were compared to the mass flows in the CFX model, which ended in the conclusion that it is hard for the one-dimensional models to understand the complex, three-dimensional flow situations, even when adjusting them to the CFX model. Anyhow, the adjustments made the model somewhat closer to the three-dimensional case, and hence CFX should be used in an earlier stage when developing C3D models.

Master of Music / School of Music, Theatre, and Dance / Slawomir Dobrzanski / This report is a study of Johann Sebastian Bach’s Partita in C minor, BWV 826; Ludwig van Beethoven’s Sonata in F-sharp major, Op.78; Fryderyk Chopin’s Scherzo in B Minor, Op.20; M. Ravel’s “Miroirs”: II. Oiseaux tristes, IV. Alborada del gracioso, V. Vallee de cloches; These compositions are part of the author’s Master’s Piano Recital given on April 12, 2017. The study mainly discusses from historical, theoretical and stylistic perspectives.

During later years, the primary care services are experiencing a heavier strain in terms of increasing expenses and higher demand for medical services. An increased awareness about pharmaceutical adverse effects and the global concern of antibiotic resistance has given self-care and active surveillance a stronger position within the primary care services. The management strategy for minor illnesses is important because care-seekers tend to repeat successful strategies from past events, and past experience with self-care drives future self-care practices. The overall aim of this thesis was to explore people’s experiences and needs when practicing self-care and receiving self-care advice for minor illnesses. This was achieved by studying people’s experiences with and knowledge of minor illnesses, self-care interventions and channels of information used when providing self-care for minor illness. Needs for confidence in self-care were studied, as well as supporting and obstructing factors in the practice of self-care. Satisfaction with telephone nursing and people’s experiences of reassurance in relation to the decision-making process in self-care for minor illness was explored. The results showed that experience correlated with self-rated knowledge of the condition, and the least common conditions most often generated a health care services consultation. To confidently practice self-care people needed good knowledge and understanding about obtaining symptom relief. Younger persons more often reported the need of having family or friends to talk to. Easy access to care was most often reported as a support in self-care, and a lack of knowledge about illnesses was most often reported as obstructing self-care. Care-seekers receiving self-care advice were less satisfied with the telephone nursing than care-seekers referred to medical care, and feeling reassured after the call was the most important factor influencing satisfaction. Self-care advice had a constricting influence on healthcare utilization, with 66.1% of the cases resulting in a lower level of care than first intended. The course of action that persons in self-care decided on was found to relate to uncertainty and perception of risk. Reassurance had the potential to allay doubts and fears to confidence, thereby influencing self-care and consultation behavior. In conclusion, symptoms of minor illness can cause uncertainty and concern, and reassurance is an important factor influencing people’s course of action when afflicted with minor illness. The nurse constitutes a calming force, and the encounter between the nurse and the care-seeker holds a unique possibility of reassurance and confidence that minor illness is self-limiting to its nature and that effective interventions can provide relief and comfort. Just as health is more than the absence of disease, self-care is more than the absence of medical care.

Allogeneic hematopoietic stem cell transplantation (allo-HCT) has been a successful cellular therapy for patients suffering from hematological malignancies for many decades; however, the beneficial effects of graft-versus-leukemia (GVL) are classically offset by graft-versus-host disease (GVHD). GVHD occurs when major and/or minor human leukocyte antigen (HLA) mismatches between donor and recipient cause rapid expansion and activation of donor effector T cells (Teffs) resulting in end organ damage to the recipient’s epithelial tissues. Given the lymphoproliferative nature of this disease, the standard treatment option is broad immunosuppression, which can result in primary disease relapse, steroid refractory GVHD, and/or opportunistic infection. A more targeted therapy that can selectively suppress GVH responses with maintained GVL responses would achieve the optimal goal of allo-HCT. Regulatory T cells (Tregs) both natural (nTregs) or induced (iTregs) could be potential cellular therapies for the treatment of GVHD, given their innate suppressive function. Initial clinical trials using nTregs have yielded positive results; however, nTreg cellular therapy has been cumbersome due to the necessity for large scale ex vivo expansion given their low yield within an apheresis product and non-specific suppression. Conversely, iTregs can be generated from naïve T cells thus decreasing ex vivo culture times and can be educated with specific antigen thus providing targeted suppression, but a consensus on their efficacy for GVHD therapy has not been reached. Therefore, we investigated the efficacy of antigen specific iTreg therapy for the prevention of GVHD while maintaining GVL responses. In Chapter 2, we evaluated the effectiveness of monoclonal HY-specific iTregs in GVHD attenuation. We chose HY as a target antigen because it is a naturally processed, ubiquitously expressed minor mismatch antigen carried by only male donors/recipients cited to increase GVHD prevalence when donor and recipient are sex-mismatched. Utilizing HY-transgenic mice in which all T cells recognize HY antigen exclusively, we generated HY specific iTregs which effectively attenuating GVHD in male, but not female recipients in three murine bone marrow transplantation (BMT) models (major mismatch, parent to F1, and miHAg mismatch). We found HY specific iTregs lost stability in female recipients but remained stable and suppressive in male recipients suggesting expression of HY antigen was required for their suppressive function and stability. GVL responses were not compromised with the addition of HY specific iTregs in recipient mice using a pre-established tumor model. Thus, HY-specific iTregs can be generated and suppress GVHD in an antigen-dependent manner while sparing the GVL effect. In Chapter 3, we extend our findings in Chapter 2, which provided proof of principle that antigen specific iTregs effectively control GVHD; however, this therapy has a limited translational potential. Therefore, we generated alloreactive CD4 and CD8 iTregs and evaluated GVHD attenuation and GVL preservation in either full or haplo-MHC mismatched BMT models. We found alloreactive CD4 iTregs significantly suppress lethal GVHD, but completely abrogated the GVL effect against aggressive tumors. Conversely, alloreactive CD8 iTregs moderately attenuated GVHD and possessed direct cytotoxicity against tumor cells. Therefore, to rescue the impaired GVL effect mediated by CD4 iTregs, we established a combinational therapy with CD8 iTregs. Indeed we found combination CD4 and CD8 iTreg therapy significantly suppressed GVHD while sparing GVL responses compared to either CD4 or CD8 singular therapy. Mechanistically, this was achieved by potent suppression of both CD4 and CD8 Teffs coupled with preserved cytolytic molecule expression by both CD8 iTregs and Teffs. Taken together, we propose antigen specific iTreg therapy can effectively attenuate GVHD while preserving GVL responses. We further uncovered unique characteristics of CD4 and CD8 iTregs that can be exploited to achieve the optimal cellular therapy following allo-HCT.

This thesis takes a fresh, character-based approach to the Íslendingasögur. It is inspired by a narratological study that unites the functional and structural role of characters with their human, individualistic portrayal. My major objective is to demonstrate the important connection between characterisation and structure in the sagas. By drawing attention to characters that I term narrative triggers, I offer a way of reading the sagas that relies both on the narrative conventions of tradition and on the less predictable, personal interactions between the cast of any given saga. In the case of both major and minor figures in the Íslendingasögur a certain type of character is often present to perform necessary motivational functions, allowing the plot to develop. In Part I I emphasise the functional aspect of these characters, before exploring unusual examples that emphasise their individuality in Part II.The motivation of the plot is linked throughout to the figure of the ójafnaðarmaðr. A secondary objective is to provide a clearer understanding of the nature and function of this commonly occurring character type. The ójafnaðarmaðr is frequently alluded to in scholarship,but this thesis provides the first in-depth study of the portrayal of these characters. The quality that informs them (ójafnaðr,‘inequity’, lit. ‘unevenness’) is a threat to one of the core values of saga society and hints at an ‘unbalancing’ of social interactions and of the narrative equilibrium itself. That this unbalance leads to changes in the social structure of the setting is a key factor in driving the plots of the sagas along. For this reason, a detailed examination of the figure of the ójafnaðarmaðr is long overdue: they can be observed to perform a specific narrative function but are always fitted to suit their particular context. Focussing on the structural conventions of character introduction, Part I establishes my methodology and catalogues the examples of characters introduced as ójafnaðarmenn. The scope is limited to those introduced as such because it allows me to establish for the first time the full corpus and conventions of these characters and their introductions. Following developments in our understanding of the oral background to the sagas, my approach to these narratives is built upon the evidence of their shared origins in pre-literate storytelling [...]. The intersection between functionality and individuality in character brings certain aspects of the Íslendingasögur to the fore. Part II of this thesis shows that in combination with the structural markers explored in Part I, the sagas employ the collective perspective of the general public, other characters and ‘irrational’ motivators such as fate to contribute to their techniques of characterisation. Because disruptive qualities speak inherently of a difference in the way an individual sees themselves and in the way the public sees them, or we as an audience are meant to see them, figures termed ójafnaðarmaðr are an ideal focal point for the development of this study.

In this dissertation, I investigate a number of interrelated developments affecting the morphosyntax of nouns in Cappadocian Greek. I specifically focus on the development of differential object marking, the loss of grammatical gender distinctions, and the neuterisation of noun inflection. My aim is to provide a diachronic account of the innovations that Cappadocian has undergone in the three domains mentioned above. !ll the innovations examined in this study have the effect of rendering the morphology and syntax of nouns in Cappadocian more like that of neuters. On account of the historical and sociolinguistic circumstances in which Cappadocian developed as well as of the superficial similarity of their outcomes to equivalent structures in Turkish, previous research has overwhelmingly treated the Cappadocian developments as instances of contact-induced change that resulted from the influence of Turkish. In this study, I examine the Cappadocian innovations from a language-internal point of view and in comparison with parallel developments attested in the other Modern Greek dialects of Asia Minor, namely Pontic, Rumeic, Pharasiot and Silliot. My comparative analysis of a wide range of dialect-internal, cross-dialectal and cross-linguistic typological evidence shows that language contact with Turkish can be identified as the main cause of change only in the case of differential object marking. On the other hand, with respect to the origins of the most pervasive innovations in gender and noun inflection, I argue that they go back to the common linguistic ancestor of the modern Asia Minor Greek dialects and do not owe their development to language contact with Turkish. I show in detail that the superficial similarity of these latter innovations’ outcomes to their Turkish equivalents in each case represents the final stage in a long series of typologically plausible, language-internal developments whose early manifestations predate the intensification of Cappadocian–Turkish linguistic and cultural exchange. These findings show that diachronic change in Cappadocian is best understood when examined within a larger Asia Minor Greek context. On the whole, they make a significant contribution to our knowledge of the history of Cappadocian and the Asia Minor Greek dialects as well as to Modern Greek dialectology more generally, and open a fresh round of discussion on the origin and development of other innovations attested in these dialects that are considered by historical linguists and Modern Greek dialectologists to be untypically Greek or contact-induced or both.

Étude théorique sur les institutions de la tutelle officieuse et de l'adoption sous l'application du Code civil de 1804. C'est une étude théorique car la tutelle officieuse n'a pas connue de nombreuses pratiques. Au travers de l'institution de l'adoption, il est analysé et supposé les applications théoriques de l'institution de la tutelle officieuse. Cette étude est à la fois historique et théorique, les liens de filiation fictive y sont analysés afin de permettre une meilleure compréhension des mécanismes d'adoption et d'attachement d'un mineur à l'apparition de l'adoption sous l'application du Code civil de 1804. / Theoretical study on the institutions of the unofficial supervision(guardianship) and the adoption under the application of the Civil code of 1804. It is a theoretical study because the unofficial supervision(guardianship) did not know of numerous practices. Through the institution of the adoption, are analyzed and supposed the theoretical applications of the institution of the unofficial supervision(guardianship). This study is historic and theoretical at once(at the same time), the links of fictitious filiation are analyzed there to allow a better understanding of the mechanisms of adoption and attachment of a minor(miner) the appearance of the adoption under the application of the Civil code of 1804.