The independent, complex role of a school nurse requires accurate documentation of assessments, interventions, and outcomes. Consistent documentation by all school nurses is crucial to study the impact of nursing interventions on children's health and success in school. While standardized nursing languages are available, the actual use of these languages is in the infancy stages of implementation. This national survey of school nurses reveals diverse practices in school nursing documentation. Using Everett Rogers' (2003) Diffusion of Innovation (DOI) theory, a web-based survey allowed respondents to identify their knowledge and attitude towards the use of standardized languages, including NANDA International (NANDA-I), Nursing Interventions Classification (NIC), and Nursing Outcomes Classification (NOC). Respondents also rated barriers to adopting the use of NANDA-I, NIC, and NOC (NNN). The results of this survey serve as a foundation for moving the practice of school nursing towards consistent documentation. Ultimately, the implementation of NNN will allow school nurses to document more consistently, base practice decisions on evidence, and improve the health and academic success of children in schools.

Ethernet as the communication medium in the enterprise data center has outlived all competing mediums and resisted the test of time with regards to speed and costs. The future is also poised for growth with 40 and 100Gps speeds just over horizon. The current state of the technology is being enhanced and extended with lossless features to allow for fabric convergence of Storage and Inter Process Communication (IPC) Networks. It is under this medium that an increase in the adoption of Remote Direct Memory Access (RDMA) over Ethernet using offloaded TCP/IP (iWARP) and Infiniband over Ethernet (RoCE) communication stacks to RDMA capable NIC adapter s (RNIC) is observed. RDMA enables direct application to application communication over the network resulting in numerous and significant benefits such as reduced CPU utilization, lower latency communications, increased energy efficiency, and reduced overall system requirements. However, with said benefits also comes increased software complexity in how RDMA interface users communicate. The RDMA communication semantics, which originate from the HPC domain, are heavily biased towards Low-Latency and High-Bandwidth communications rather than Reliability, Availability, and Serviceability (RAS). As adoption increases, and enterprise data centers begins to leverage RDMA over Ethernet, enhancements to the OS stack software architecture and design of the components involved is required to address these deficiencies. Operating system interfaces, device drivers, adapter hardware design, and embedded firmware features must be viewed from a high-availability and maintainability point of view. RAS enhancements for RDMA communications proposes the software architectural tradeoffs for enhancing the iWARP and RoCE RDMA implementations for communications in the enterprise data center, with new and traditional RAS features for existing communications stacks and devices. The architecture leverages software enhancements in traceability, availability, maintainability, serviceability, fault-isolation and resource management; such that in the advent of errors, the probability that the forensics data points to identify root cause are immediately and automatically available is increased. / text

In a theoretical part of the paper, the main focus is on characteristics and terminology of premature babies, breastfeeding, classification systems NANDA International, NIC and NOC, about also management which is an integral part of nursing process. Both quantitative and qualitative researches were used to obtain and process all data. In quantitative method was used a method of document was used, content analysis and quasiexperiment. Results of quantitative research were processed in SPSS software, version 16.0 Statistical Package for Social Sciences, where a method of nonparametric correlation was used. A pen and paper interview with open questions was used in qualitative section of research. Before the research itself, a deputy of nursing care in hospital Nemocnice České Budějovice, a.s. was addressed. The research was implemented between February 2013 and April 2013. First research cluster consisted of nine mothers and eleven premature babies in which two of the mothers had twins. Basic criteria for entering the research, was a necessary hospitalization of both the mother and the child, which the hospital Nemocnice České Budějovice, a. s. offers. The major criterion was an initiated lactation. Second research sample consisted of nurses working at Stanice intermediární péče II. (IMP II ? rooming) of Nemocnice České Budějovice a. s. First of goals was to create files from classification systems NANDA International, NIC, NOC for development and support of breastfeeding for premature babies. The main goal of this work was to create a comprehensive documentation mediated by classification systems NANDA International, NIC, NOC for growth and support of premature babies. The theoretical content of the paper itself was used to create documentation and its usage in praxis. It was not mentioned to create new, but to apply already well known, verified and proven classification systems, which can make not only breastfeeding, but also the daily routine of a nurse more efficient. The suggested documentation solves the issues of breastfeeding of premature babies to help mothers, but also to increase a professional prestige of nurses. Documentation was compiled to include all the necessary information needed for the correct nursing process method. Significant part of documentation is a preliminary case history of mother and child, which offered valuable information. Further attribute were nursing diagnoses dealing with breastfeeding issues of premature babies and intervention realized during hospitalization. It was necessary to address each entry concerned with premature babies individually, based on complex evaluation of overall condition. Many pieces of knowledge from specialized literature on the topic of premature babies and personal experience of doc. PhDr. Mária Bolendovičová, PhD. were used to create the documentation. Second aim of the study was verification of selected specimens on clinical praxis. Third aim was to monitor nurses in Stanice intermediární péče II. (IMP II ? rooming) and their attitude to usage of classification systems NANDA International, NIC and NOC. Based on interviews with nurses it was proven that nurses have better knowledge of NANDA Internationals classification systems than knowledge of NIC and NOC. Final documentation was tested in the perspective of medical staff and its exploitability in clinical praxis. It was found that nurses sense the classification systems NANDA International, NIC and NOC as an appropriate tool, but only with more staff present to work on station. From statements of nurses was clear that establishing a diagnoses is a responsibility of each nurse taking part in nursing process.

Made available in DSpace on 2014-06-11T19:26:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2001Bitstream added on 2014-06-13T20:15:08Z : No. of bitstreams: 1 monteirojunior_o_me_botfm.pdf: 372086 bytes, checksum: e70c404b57dbf716ae6468fc47c63be9 (MD5) / Objetivando estudar a prevalência de neoplasia intra-epitelial cervical (NIC) em mulheres soro-positivas para o vírus da imunodeficiência humana (HIV) ao compará-las com um grupo controle de mulheres soro-negativas, foi realizado um trabalho retrospectivo em que foram avaliadas 86 mulheres HIV positivas e 86 mulheres HIV negativas, que freqüentaram um serviço público de acompanhamento em DST/AIDS na cidade de Campo Grande, Mato Grosso do Sul, Brasil. Foram realizadas avaliações citológicas pelo Papanocolaou, colposcopias e biópsias quando indicadas. Encontrou-se uma prevalência maior de NIC no grupo de mulheres HIV positivas em comparação ao grupo de mulheres HIV negativas, e esta diferença foi estatisticamente significativa. Conclui o autor que, sendo o câncer do colo uterino uma patologia previnível e com o atual aumento da expectativa de vida das pacientes HIV positivas, este grupo de mulheres merece atenção ginecológica diferenciada com consultas mais frequentes e livre acesso à colposcopia. / Objetiving to study the prevalence of cervical intraepithelial neoplasia (CIN) in human immunodeficiency virus (HIV) – infected women and to compar with a group control of seronegative women, it was realized a retrospective study being assessed 86 HIV – infected and 86 HIV – unifected women, who were attended in a public service of accompaniment in TSD/AIDS in Campo Grande City, Mato Grosso do Sul, Brazil. Were realized evolution cytologic for the Papanicolaou test, colposcopy and biopsies, when indicated. It was found a prevalence of CIN significantly greater in HIV – seropositive women than in seronegative women. In conclusion, being the cervical cancer a pathology that can be prevented and with the current increase of the life’s expectative of the HIV – seropositive women, this group of women needs a better gynecologic atenttion with visits and Papanicolaou smears more often and free access to colposcopy.

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, 2006. / Submitted by wesley oliveira leite (leite.wesley@yahoo.com.br) on 2009-11-12T22:27:21Z No. of bitstreams: 1 Dissert KLISSIA PIRES SOUZA PICCININ.pdf: 594769 bytes, checksum: 96b64b73835fc8465ff0aa1d324e719c (MD5) / Approved for entry into archive by Gomes Neide(nagomes2005@gmail.com) on 2010-07-13T13:02:02Z (GMT) No. of bitstreams: 1 Dissert KLISSIA PIRES SOUZA PICCININ.pdf: 594769 bytes, checksum: 96b64b73835fc8465ff0aa1d324e719c (MD5) / Made available in DSpace on 2010-07-13T13:02:02Z (GMT). No. of bitstreams: 1 Dissert KLISSIA PIRES SOUZA PICCININ.pdf: 594769 bytes, checksum: 96b64b73835fc8465ff0aa1d324e719c (MD5) Previous issue date: 2006 / A granzima B é uma serino-protease sintetizada pelos linfócitos T citotóxicos ativados por um estímulo exógeno. O linfócito T citotóxico é o principal efetor no processo de erradicação de células infectadas por vírus e células neoplásicas. Em associação com a perforina, a granzima B induz apoptose na célula alvo. O objetivo desta pesquisa foi avaliar quantitativamente, por estudo imuno-histoquímico, a expressão linfocitária da granzima B na neoplasia intra-epitelial cervical de pacientes infectadas pelo HIV. Participaram da pesquisa 71 pacientes, sendo 36 HIV-positivo e 35 controles. A maioria das pacientes do grupo HIV-positivo apresentava contagem de células CD4>200/mm³ e utilizava terapia anti-retroviral potente. Os valores medianos para a granzima B em 20 campos de grande aumento (epiteliais e estromais) no grupo HIV-positivo e no grupo controle foram respectivamente: sem neoplasia (20,5 e 4,6), NIC I (54,0 e 40,3), NIC II e NIC III (36,0 e 58,7). Não houve diferença estatisticamente significante entre a NIC de pacientes HIV-positivo e controles. Portanto, a alta incidência e recorrência de NIC nas pacientes infectadas pelo HIV não parecem ser decorrentes de alteração na expressão linfocitária da granzima B. _______________________________________________________________________________________ ABSTRACT / Granzyme B is a serine protease synthesized in activated cytotoxic T lymphocyte after exogenous stimulation. Cytotoxic T lymphocyte are the main effector in eradication process of neoplasic cell and virus infected cell. With perforin, granzyme B discharge apoptosis signal to a target cell. The objective of this study was to evaluate granzyme B expression in lymphocytes by immunohistochemistry staining of cervical intraepithelial neoplasia (CIN) in HIV-infected women. A total of 71 pacients have participated of this study: 36 HIV-positive and 35 controls. The majority of HIV-infected women group received highly antiretroviral therapy (HAART) and presented CD4-cell count >200/mm³. The activated cytotoxic T lymphocyte mean value in 20 fields (HPF400X), in both epithelials and stromals pars from HIV-positive group and control group were, respectively: without neoplasia (20,5 and 4,6), CIN I (54,0 and 40,3), CIN II and CIN III (36,0 and 58,7). There weren’t significantly difference between CIN from HIV positive patients and controls. Thus, the high incidence and recorrence of CIN from HIV-infected women weren’t resulting from granzyme B altered expression in lymphocytes.

This paper deals, building on a ground defined by Heidegger's What is Metaphysics?, with a single question: in what sense do being and the no-thing belong together? This question is being addressed at two parallel levels. Based on a detailed interpretation of key text passages that have often been examined insufficiently due to their lack of accessibility, it aims to gain a complex insight into the issue and interpret it in its many nuances of meaning. At the same time, its aim is to articulate a general philosophical significance of the intrinsic connection between being and the no-thing; to what extent it affects the innermost intention of Heidegger's fundamental ontology as such, i.e. raising the question of the meaning of being. The paper builds on a phenomenological description of the original experience of the no-thing and captures a transformation of a human being into a pure Da-sein, which he goes through during this experience. Since the experience of the no-thing according to Heidegger is identical to the basic mood of dread, this piece of work depicts it in relation to seemingly similar, but in their meaning actually opposite moods: fear and, most importantly, abysmal boredom. Subsequently, it puts forward an interpretation of the no-thing's own ontological significance and thus...

La presente investigación "NIC 38 Activos Intangibles y su Impacto Financiero y Tributario en las empresas de tecnologías informáticas en San Isidro, año 2018" plantea determinar el impacto financiero como tributario que tiene esta NIC, es por ello que necesitamos reconocer y medir un intangible dentro de una organización. En el Marco Teórico, realizamos la investigación a través de fuentes primarias en las cuales se desarrollan conceptos generales de la NIC 38 como son definiciones, objetivos, alcance, reconocimiento, medición e información a revelar y su relación con las empresas de tecnologías informáticas, también el impacto financiero y tributario de la NIC. Luego, en el Plan de investigación, mostraremos los problemas, objetivos e hipótesis generales como específicos. En la metodología se define la población y muestra para aplicar el método de investigación mixta, que se encarga de obtener la información tanto cualitativa y cuantitativa, a través de entrevistas en profundidad a expertos en NIIF y tributación; y encuestas a contadores de empresas del sector. En el Desarrollo, plasmaremos la aplicación de la metodología y se desarrollará el caso práctico antes y después de aplicar la NIC. Posteriormente, en el Análisis de Resultados, realizamos el análisis de los instrumentos aplicados en las entrevistas, encuestas y el resultado del caso práctico. Concluyendo con la validación de las hipótesis generales y específicas con la aplicación correcta de la NIC 38 y con ello verificar si impacta financieramente y tributariamente y ante ello planteamos recomendaciones para un correcto uso de la norma. / This research entitled "IAS 38: Intangible Assets and their Financial and Tax Effect in Information Technology Companies located in San Isidro, 2018" proposes to determine both the financial and tax effect of this IAS. For this purpose, we need to identify, recognize and measure an intangible asset within an organization. In the Theoretical Framework, research is carried out through primary sources in which the general concepts of IAS 38 are developed. This includes definitions, objectives, scope, recognition, measurement, data and their association with the IT companies as well as the financial and tax effect of the aforementioned IAS. In the Research Plan, we will describe the problems, objectives and hypotheses both general and specific. In the Methodology, we define the population and sample in order to apply the mixed methods research, which collects and analyzes qualitative and quantitative data using in-depth interviews with IAS and taxation experts; and surveys conducted to accountants currently working in the relevant field. In the Research Development, the application of the methodology will be shown and the case study will be developed before and after the application of the IAS 38. Subsequently, in the Analysis of Results, we study the instruments applied in the interviews, surveys and the outcome of the case study. To conclude, the general and specific hypotheses are validated by applying the IAS 38 and we can determine if they impact the IT companies financially and tributarily. If this is the case, we will propose recommendations for the correct use. / Tesis

The prevailing view is that enhancement of dopamine (DA) transmission in the mesolimbic system consisting of DA neurons in the ventral tegmental area (VTA) that project to the nucleus accumbens (NAc) underlies the rewarding properties of ethanol (EtOH) and nicotine (NIC). Although the dogma is that EtOH enhancement of DA neural activity contributes to enhancement of DA transmission, DA neurons are not sensitive to rewarding levels of EtOH. However, VTA GABA neurons are sensitive to low-dose EtOH. We have shown previously that EtOH modulation of DA release in the NAc is mediated by α6-containing nicotinic receptors (α6*-nAChRs), that α6*-nAChRs mediate low-dose EtOH effects on VTA GABA neurons and EtOH preference, and α6*-nAChRs may be a molecular target for low-dose EtOH. Thus, the most sensitive target for reward-relevant EtOH modulation of mesolimbic DA transmission and the involvement of α6*-nAChRs in the mesolimbic DA reward system remains to be elucidated. The aim of this study was to evaluate EtOH effects on VTA GABAergic input to CINs and DA release in the NAc. Using DIO channel rhodopsin-2 (ChR2) viral injections into the VTA of VGAT Cre mice, we found that VTA GABA neurons send an inhibitory projection to CINs, replicating what has been demonstrated by others. This study investigated the acute and chronic effects of EtOH at this synapse. We demonstrate that EtOH markedly enhances CIN firing rate and that these effects are blocked by the α6-conotoxin MII (α-Ctx MII), knockout of accumbal α6*-nAChRs with α6-shRNA, and atypical GABA receptor antagonists. This study also investigated plasticity at this synapse. We demonstrate that a low frequency stimulation (LFS; 1 Hz, 240 pulses) causes inhibitory long-term depression at this synapse (CIN-iLTD) which is also blocked by α-Ctx MII, α6-shRNA, and atypical GABA receptor antagonists. We also show that CIN-iLTD is blocked in EtOH-dependent mice. Taken together, these findings suggest that EtOH affects the VTA GABAergic projection to CINs via α6*-nAChRs and that atypical GABA receptors also play a role.

El presente trabajo de investigación de tesis tiene como objetivo determinar el impacto en los Estados Financieros y en el Impuesto a la Renta de la NIC 36: Deterioro del valor de los Activos y su impacto en los Estados Financieros y en el Impuesto a la Renta en las empresas del sector pesquero que producen y exportan harina y aceite de pescado en Lima, año 2018. La presente investigación comprende los temas más sobresalientes de la NIC 36 como son los indicios de deterioro, alcance, reconocimiento y medición de un activo en deterioro. Capítulo I Marco teórico, consiste en una investigación mediante la información de fuentes primarias y conceptos que definan a las normas internacionales de información financiera; así como el impacto en los Estados Financieros y en el Impuesto a la Renta del sector pesquero. Capítulo II Plan de investigación, se plantea la situación problemática de la tesis, así como el problema principal y específico, objetivo general y específicos, la hipótesis inicial y específico. Capítulo III Metodología, se determinó la población, así como la muestra para las investigaciones cualitativas y cuantitativas. Capítulo IV Desarrollo de Investigación, se realizó el trabajo de campo por medio de la entrevista a profundidad, cuestionario y análisis para el desarrollo del caso práctico. Capítulo V Análisis de Resultados de la investigación, se desarrolla casos prácticos que nos permiten aplicar situaciones basadas en la NIC 36, concluyendo con la validación de la hipótesis en base a resultados estadísticos. / The objective of this thesis research work is to determine the impact on Financial Statements and Income Tax of IAS 36: Deterioration of the value of the Assets and their impact on the Financial Statements and Income Tax in companies in the fishing sector that produce and export fishmeal and fish oil in Lima, year 2018. The present investigation includes the most outstanding issues of IAS 36, such as the indications of impairment, scope, recognition and measurement of a deteriorating asset. Chapter I Theoretical framework, it consists of an investigation through the information of primary sources and concepts that define the international financial information standards; as well as the impact on the Financial Statements and Income Tax of the fishing sector. Chapter II Plan of investigation, the problematic situation of the thesis is raised, as well as the main and specific problem, general and specific objective, the initial and specific hypothesis. Chapter III Methodology, the population was determined, as well as the sample for qualitative and quantitative research. Chapter IV Development of Investigation, the field work was carried out through the in-depth interview, questionnaire and analysis for the development of the practical case. Chapter V Analysis of Research Results, practical cases are developed that allow us to apply situations based on IAS 36, concluding with the validation of the hypothesis based on statistical results. / Tesis

El presente trabajo de investigación denominado: “Evaluación del Impacto Financiero y Tributario en la transición de la NIC 17 a la NIIF 16 en el sector minero", tiene como objetivo ilustrar a las empresas del sector, sobre la trascendencia de la nueva norma de arrendamientos en los estados financieros. El estudio se encuentra dividido en seis capítulos principales. En el marco teórico se presentan los constructos fundamentales del estudio, en los cuales se definen los conceptos clave que sitúan al lector en el contexto de la investigación. Acto seguido se expone el plan de investigación, en el cual se identifica el problema, la hipótesis planteada y los objetivos trazados. Más adelante se emplea la metodología mixta para profundizar en la percepción de las empresas del sector y medir su conocimiento sobre la nueva norma. Después se presentan los resultados del estudio y mediante la aplicación de un caso, se pretende ilustrar los principales cambios de la nueva norma. A continuación, se analizan los resultados de la investigación y se pretende evaluar el impacto en la transición hacia una nueva partiendo de los resultados de la investigación mixta y la literatura consultada. Finalmente, se concluye que la nueva norma traerá beneficios que mejoran la transparencia y la comparabilidad de la información, pero tendrá consecuencias en los contratos alquiler y los contratos de operación minera que involucran el arrendamiento de maquinaria y equipos, que pueden afectar las condiciones de los convenios de deuda y la calificación crediticia de las compañías mineras. / This research paper entitled: "Evaluation of Financial Impact and Taxation in the transition from IAS 17 to IFRS 16 in the mining industry", aims to illustrate to companies in the industry, about the importance of the new accounting standard for leases in the financial statements. The study is divided into six main chapters. In the theoretical framework the main constructs of the study are presented, in which the key concepts that put the reader in the context of the investigation are defined. Then is exposed the research plan, in which is identified the problem, the hypothesis and objectives. Later, the mixed methodology is used to deepen the perception of companies in the sector and to measure their knowledge of the new standard. After, the results of the study are presented and by applying a case, are intended to illustrate the main changes in the new standard. Then the research results are analyzed and pretend to assess the impact on the transition to a new standard, on the results of the joint research and the literature. Finally, we conclude that the new standard will bring benefits to improve transparency and comparability of information, but it will have consequences in the contracts rent and contract mining operation involving the leasing of machinery and equipment, which may affect the conditions of debt covenants and the rating credit of mining companies. / Trabajo de Suficiencia Profesional