Går det att förutspå framtida aktiepriser genom att undersöka hur priser, på samma aktier, rört sig historisk? För att undersöka detta har vi använt oss av teknisk analys. Denna uppsats undersöker om teknisk analys på stockholmsbörsen kan användas för att uppnå högre avkastning än en s.k. Buy and Hold Strategi. I undersökningen används Relative Strength Index som teknisk analysmetod för att försöka förutspå framtida upp- och nedgångar i aktiepriser på tjugofem av de högst omsatta aktierna på Stockholmsbörsen. I undersökningen kompletteras Relative Strength Index med en Money Management strategi, som är till för att begränsa förlusterna. Undersökningsperioden sträcker sig mellan januari 2001 och juni 2008.   Svaga statistiska resultat, kombinerat med generellt sett lägre avkastningar, säger oss att förutspå framtida upp- och nedgångar på Stockholmsbörsen med hjälp av Relative Strength Index ej är att föredra framför strategin Buy and Hold.

Due to the recent increase of computer programmers, and asa result, sufferers from Repetitive Strain Injury (RSI),programming by voice is becoming an important alternativeto keyboard-based input. Using speech recognition softwareis more difficult for programming tasks than naturallanguage. This is because writing code requires punctuation,symbols, and abbreviations that need to be spelled out. It isalso not limited to writing code, but also includes navigation,editing, and error correction. Therefore, an easy and flexibleway of working with code by voice is therefore. This studyexamines the efficiency of vocal programming in differentparadigms (namely, the imperative and reactive paradigm).We survey which advantages and challenges the reactiveand imperative paradigm have within this field. Bydiscussing if and how the reactive paradigm could beincorporated into future tools and covering the mostcommon challenges, we hope to provide a base for furtherstudies on programming reactively by voice. A brief surveyof tools for vocal programming is carried out. Using TalonVoice, examples written in Java and RxJava, we measure theperformance of the respective paradigms, by recording thenumber of words, syllables, and necessary pauses used whenproducing code vocally. The results vary in vocal load, butboth paradigms have advantages in vocal programming. Theresults also show that reactive programming, thoughgenerally requiring more code for the same tasks asimperative code, does not require the vocal programmer toutter as many words per character as within the imperativeparadigm. The authors discuss the effects of cognitive load inrelation to the presented findings.

TTP protocol for managing hierarchy trees of the RTCP feedback channel represents the mechanism for transferring the big amount of data from end users via the “narrow” feedback channel. We are not speaking about thousands of users but about millions of users, which are using services like IPTV. The method of a data summarization is used for this purpose in selected network nodes. The summarized message is transferred and summarized again in higher levels of the hierarchical tree. Both methods allow reducing the amount of data and help to increase information content transferred via the feedback channel. Finding of the correct end user position in a network is also very important aspect. The user must be able to find the closest summarization node with this information and starts sending out the messages to this node for processing. There are several methods for constructing and managing the asynchronous feedback channel that are introduced in this work.

The thesis is concerned with the design and optimization of a trading strategy on currency markets in order to maximize profit on the EURUSD currency pair. The strategy is based on standard technical indicators and is tested in demo account environment. The thesis describes the whole development from initial design to an optimized version of the draft.

This study performs a comparative analysis and evaluates the impact of different Relative Strenght Index (RSI) and stop loss configurations on a trading algorithm based on candlesticks patterns. It is tested on both the Swedish OMXS30 market and the UK FTSE100 market. By tweaking the configurations, RSI and stop loss was found to have a substantial impact on the performance of the algorithm. On both OMXS30 and FTSE100 markets the difference between configurations was shown to be significant / Denna studie gör en jämförelse och analyserar olika Relative Strenght Index (RSI) och stop loss-konfigurationers påverkan på en tradingalgoritm som är baserad på candlestick patterns. Algoritmen är testad på svenska OMXS30 och brittiska FTSE100. Genom att testa olika konfigurationer blev slutsatsen att RSI och stop loss hade en stor påverkar på algoritmens resultat. På både OMXS30 och FTSE100 var skillnaden mellan konfigurationerna signifikant.

With the rise in demand for renewable energy sources, photovoltaics have become increasingly popular as a means of reducing household dependence on the utility grid for power. But solar panels generate dc electricity, a dc to ac inverter is required to allow the energy to be used by the existing ac electrical distribution. Traditional full bridge inverters are able to accomplish this, but they suffer from many problems such as low efficiency, large size, high cost, and generation of electrical noise, especially common mode noise. Efforts to solve these issues have resulted in improved solutions, but they do not eliminate all of the problems and even exaggerate some of them. Soft switching inverters are able to achieve high efficiency by eliminating the switching losses of the power stage switches. Since this action requires additional components that are large and have additional losses associated with them, these topologies have traditionally been limited to higher power levels. The resonant snubber inverter is a soft switching topology that eliminates many of these problems by taking advantage of the bipolar switching action of the power stage switches. This allows for a significant size reduction in the additional parts and elimination of common mode noise, making it an ideal candidate for lower power levels. Previous attempts to implement the resonant snubber inverter have been hampered by low efficiency due to parasitics of the silicon devices used, but, with recent developments in new semiconductor technologies such as silicon carbide and gallium nitride, these problems can be minimized and possibly eliminated. The goal of this thesis is to design and experimentally verify a design of a resonant snubber inverter that takes advantage of new semiconductor materials to improve efficiency while maintaining minimal additional, parts, simple control, and elimination of common mode noise. A 600 W prototype is built. The performance improvements over previous designs are verified and compared to alternative high efficiency solutions along with a novel control technique for the auxiliary resonant snubber. A standalone and grid tie controller are developed to verify that the auxiliary resonant snubber and new auxiliary control technique does not complicate the closed loop control. / Master of Science

O glioblastoma (GBM) é o tumor primário do sistema nervoso central mais frequente no adulto, com sobrevida média de aproximadamente 12 meses. Múltiplas alterações genéticas e epigenéticas presentes neste tumor determinam sua biologia e fenótipo bastante agressivos. Assim, o presente estudo objetivou estudar a expressão dos genes envolvidos no Índice de Radiossensibilidade (RSI) e do gene MGMT em amostras de tumor primário humano de GBM, buscando identificar a associação destes com radiossensibilidade e sobrevida. Foram analisadas as características epidemiológicas, de evolução e desfecho clínico de 28 pacientes com GBM que fizeram uso de temozolamida (TMZ), cujos prontuários físicos e eletrônicos foram revisados no Serviço de Arquivo Médico (SAM) e Sistema Athos. Foi observado que 64,29% dos pacientes possuíam mais de 50 anos de idade e eram do sexo masculino; 86,36% possuíam o Karnofsky Performance Status acima ou igual a 80%; 57,14% possuíam localização não eloquente; 78,57% apresentavam lesão residual; 89,29% não foram reexpostos à radioterapia; 64,29% não fizeram uso de temozolamida metronômica; 96,43% não foram submetidos a outra quimioterapia; 78,57% não realizaram reabordagem cirúrgica; 60,71% tiveram progressão tardia e/ou não tiveram progressão da doença. Também foi evidenciado que tanto a regressão bruta de cada gene separadamente, quanto a regressão ajustada para os fatores clínicos mais relevantes (idade ao diagnóstico, localização do tumor e presença de lesão residual) não evidenciaram significância estatística em relação à progressão tardia. A relação entre o tempo de sobrevida global e a expressão dos genes ajustada para os mesmos fatores clínicos evidenciou significância estatística para os genes RELA (HR 1,265 / p = 0,01); c-Jun (HR 1,237 / p = 0,03) e c-ABL (HR 0,33 / p = 0,04). A análise de sobrevida livre de progressão ajustada mostrou diferença significativa (p = 0,04) entre os grupos com tumor de localização eloquente e não eloquente, assim como para a expressão do gene RELA (HR 1,107 / p = 0,03). Em relação à expressão gênica e a sobrevida global ou sobrevida livre de progressão dos pacientes pelo teste de Log-rank não foi observada diferença estatística. Na análise da expressão gênica com as variáveis clínico-epidemiológicas, a expressão do gene SUMO1 foi significativamente aumentada (p = 0,009) no grupo com progressão tardia com relação ao grupo com progressão precoce da doença, a expressão do AR apresentou aumento significativo (p = 0,021) no grupo em que a TMZ metronômica não foi administrada e as expressões dos genes RELA (p = 0,03),c-Jun (p = 0,005), STAT1 (p = 0.009) e HDAC1 (p = 0.044) estava elevada nos pacientes que apresentaram o exame neurológico pré-operatório normal. Esses dados indicam que o conjunto dos genes do RSI e o MGMT não demonstraram ser preditores de radiossensibilidade. Podemos inferir que RELA, c-Jun e c-ABL são potenciais marcadores de pior prognóstico e que SUMO1 pode ser um marcador de bom prognóstico / Glioblastoma (GBM) is the primary tumor of the central nervous system most common in adults, with a median survival of approximately 12 months. Multiple genetic and epigenetic alterations present in this tumor determine its biology and phenotype very aggressive. Thus, the present study aimed to study the expression of genes involved in radiosensitivity index (RSI) and the MGMT gene in GBM human primary tumor samples, seeking to identify the association of these with radiosensitivity and survival. The epidemiological evolution and clinical characteristics of 28 GBM patients who used temozolamide (TMZ), whose physical and electronic medical records were reviewed in the Medical File Service (SAM) and Athos System, were analyzed. It was observed that 64.29% of the patients were over 50 years of age and were male; 86.36% had Karnofsky Performance Status of 80 or more; 57.14% had no eloquent location; 78.57% had residual lesion; 89.29% did not have reexposure to radiotherapy; 64.29% did not use metronomic temozolamide; 96.43% did not undergo another chemotherapy; 78.57% did not undergo surgical reassessment; 60.71% had late progression and / or had no disease progression. It was also evidenced that both the gross regression of each gene separately and the regression adjusted for the most relevant clinical factors (age at diagnosis, tumor location and presence of residual lesion) did not show statistical significance in relation to the late progression. The relationship between overall survival time and gene expression adjusted for the same clinical factors showed statistical significance for RELA genes (HR 1.265 / p = 0.01), c-Jun (HR 1.237 / p = 0.03) and c-ABL (HR 0.33 / p = 0.04). Adjusted progression-free survival analysis showed a significant difference (p = 0.04) between the groups with eloquent and noneloquent localization, as well as RELA gene expression (HR 1,107 / p = 0.03). Regarding the gene expression and overall survival or progression-free survival of the patients by the Logrank test, no statistical difference was observed. In the analysis of the expression genes with the clinical-epidemiological variables the expression of the SUMO1 gene was significantly increased (p = 0.009) in the group with late progression in relation to the group with early disease progression, the expression of AR showed a significant increase (p = 0.021) in the group in which the metronomic TMZ was not administered and the RELA (p = 0.03), c-Jun (p = 0.005), STAT1 (p = 0.009) and HDAC1 (p = 0.044) gene expressions were elevated in patients who had normal preoperative neurologic examination. These data indicate that the set of RSIgenes and MGMT were not shown to be predictors of radiosensitivity. We can infer that RELA, c-Jun and c-ABL are potential markers of worse prognosis and that SUMO1 may be a marker of good prognosis

O glioblastoma (GBM) é o tumor primário do sistema nervoso central mais frequente no adulto, com sobrevida média de aproximadamente 12 meses. Múltiplas alterações genéticas e epigenéticas presentes neste tumor determinam sua biologia e fenótipo bastante agressivos. Assim, o presente estudo objetivou estudar a expressão dos genes envolvidos no Índice de Radiossensibilidade (RSI) e do gene MGMT em amostras de tumor primário humano de GBM, buscando identificar a associação destes com radiossensibilidade e sobrevida. Foram analisadas as características epidemiológicas, de evolução e desfecho clínico de 28 pacientes com GBM que fizeram uso de temozolamida (TMZ), cujos prontuários físicos e eletrônicos foram revisados no Serviço de Arquivo Médico (SAM) e Sistema Athos. Foi observado que 64,29% dos pacientes possuíam mais de 50 anos de idade e eram do sexo masculino; 86,36% possuíam o Karnofsky Performance Status acima ou igual a 80%; 57,14% possuíam localização não eloquente; 78,57% apresentavam lesão residual; 89,29% não foram reexpostos à radioterapia; 64,29% não fizeram uso de temozolamida metronômica; 96,43% não foram submetidos a outra quimioterapia; 78,57% não realizaram reabordagem cirúrgica; 60,71% tiveram progressão tardia e/ou não tiveram progressão da doença. Também foi evidenciado que tanto a regressão bruta de cada gene separadamente, quanto a regressão ajustada para os fatores clínicos mais relevantes (idade ao diagnóstico, localização do tumor e presença de lesão residual) não evidenciaram significância estatística em relação à progressão tardia. A relação entre o tempo de sobrevida global e a expressão dos genes ajustada para os mesmos fatores clínicos evidenciou significância estatística para os genes RELA (HR 1,265 / p = 0,01); c-Jun (HR 1,237 / p = 0,03) e c-ABL (HR 0,33 / p = 0,04). A análise de sobrevida livre de progressão ajustada mostrou diferença significativa (p = 0,04) entre os grupos com tumor de localização eloquente e não eloquente, assim como para a expressão do gene RELA (HR 1,107 / p = 0,03). Em relação à expressão gênica e a sobrevida global ou sobrevida livre de progressão dos pacientes pelo teste de Log-rank não foi observada diferença estatística. Na análise da expressão gênica com as variáveis clínico-epidemiológicas, a expressão do gene SUMO1 foi significativamente aumentada (p = 0,009) no grupo com progressão tardia com relação ao grupo com progressão precoce da doença, a expressão do AR apresentou aumento significativo (p = 0,021) no grupo em que a TMZ metronômica não foi administrada e as expressões dos genes RELA (p = 0,03),c-Jun (p = 0,005), STAT1 (p = 0.009) e HDAC1 (p = 0.044) estava elevada nos pacientes que apresentaram o exame neurológico pré-operatório normal. Esses dados indicam que o conjunto dos genes do RSI e o MGMT não demonstraram ser preditores de radiossensibilidade. Podemos inferir que RELA, c-Jun e c-ABL são potenciais marcadores de pior prognóstico e que SUMO1 pode ser um marcador de bom prognóstico / Glioblastoma (GBM) is the primary tumor of the central nervous system most common in adults, with a median survival of approximately 12 months. Multiple genetic and epigenetic alterations present in this tumor determine its biology and phenotype very aggressive. Thus, the present study aimed to study the expression of genes involved in radiosensitivity index (RSI) and the MGMT gene in GBM human primary tumor samples, seeking to identify the association of these with radiosensitivity and survival. The epidemiological evolution and clinical characteristics of 28 GBM patients who used temozolamide (TMZ), whose physical and electronic medical records were reviewed in the Medical File Service (SAM) and Athos System, were analyzed. It was observed that 64.29% of the patients were over 50 years of age and were male; 86.36% had Karnofsky Performance Status of 80 or more; 57.14% had no eloquent location; 78.57% had residual lesion; 89.29% did not have reexposure to radiotherapy; 64.29% did not use metronomic temozolamide; 96.43% did not undergo another chemotherapy; 78.57% did not undergo surgical reassessment; 60.71% had late progression and / or had no disease progression. It was also evidenced that both the gross regression of each gene separately and the regression adjusted for the most relevant clinical factors (age at diagnosis, tumor location and presence of residual lesion) did not show statistical significance in relation to the late progression. The relationship between overall survival time and gene expression adjusted for the same clinical factors showed statistical significance for RELA genes (HR 1.265 / p = 0.01), c-Jun (HR 1.237 / p = 0.03) and c-ABL (HR 0.33 / p = 0.04). Adjusted progression-free survival analysis showed a significant difference (p = 0.04) between the groups with eloquent and noneloquent localization, as well as RELA gene expression (HR 1,107 / p = 0.03). Regarding the gene expression and overall survival or progression-free survival of the patients by the Logrank test, no statistical difference was observed. In the analysis of the expression genes with the clinical-epidemiological variables the expression of the SUMO1 gene was significantly increased (p = 0.009) in the group with late progression in relation to the group with early disease progression, the expression of AR showed a significant increase (p = 0.021) in the group in which the metronomic TMZ was not administered and the RELA (p = 0.03), c-Jun (p = 0.005), STAT1 (p = 0.009) and HDAC1 (p = 0.044) gene expressions were elevated in patients who had normal preoperative neurologic examination. These data indicate that the set of RSIgenes and MGMT were not shown to be predictors of radiosensitivity. We can infer that RELA, c-Jun and c-ABL are potential markers of worse prognosis and that SUMO1 may be a marker of good prognosis

Introduktion: Smartphoneapplikationen My Jump2 har bedömts att ha större tillgänglighet och inte vara beroende av labbutrustning vid vertikala hopptester. I jämförelse med kraftplatta (golden standard) har applikationen visat sig valid och reliabel. My Jump2 har uppvisat mycket bra- perfekt korrelation mot övrig kraftutrustning. Jämförelse mellan My Jump2 och kliniska tester är ännu inte beprövat på detta område. Syfte: Syftet med denna kliniska studie var att analysera samband och korrelationer mellan värden från My Jump2 och kliniska tester gällande funktionell bedömning av underbenets muskulatur. Därför jämfördes värden hos aktiva, icke skadade män och kvinnor. Metod: Totalt 26st kvinnor och män testades vid ett indivduellt testtilfälle i gymmiljö. 3rep MAX, lunge-test, antal tåhävningar och bäst av tre drop jump analyserades på dominanta benet. Pearsons korrelation användes för att undersöka samband mellan My Jump2 och kliniska tester och ANCOVA för att undersöka skillnader mellan deltagare. Resultat: Huvudfynden var att MyJump2 uppvisade två signifikanta korrelationssamband för männen och ett för kvinnorna vid jämförelse med kliniska tester. Signifikanta skillnader gällande RSI-värde med hänsyn till muskelstyrka 3rep MAX (95% CI; 0,01-0,19, p = 0,03) fanns mellan könen. Ingen signifikant skillnad i stiffness med hänsyn till ROM (95% CI; -0,11- 0,55, p = 0,18) justerat mot kön (95% CI; -0,78-2,03, p = 0,37) återfanns. Konklusion: Resultaten indikerar på att vidare forskning är nödvändig. Endast få signifikanta korrelationssamband återfanns mellan värden från My Jump2 och kliniska tester. My Jump2 visar signifikanta nivåer för RSI-värdet med hänsyn till muskelstyrka och kön. Studien kan inte bekräfta förväntade samband mellan My Jump2 och kliniska tester för underbenet. / Introduction: The smartphoneapplication My Jump2 has been assessed in rescent research for its validity and reliability. In comparison to golden standard devices, My Jump2 shows great- perfect correlation measuring jump height. Eventhough former results indicate usability of the smarthphoneapplication, further research is needed in order to evaluate clinical usefulness in a more expanded population. Aim: The aim of this study was to analyse the relationship and correlations between measured values from My Jump2 and clinical testing of lower extremity performance. This in an active and recreational population, both male and female. Method: A total of 26 males and females were tested individually in a gym-location. 3rep MAX, lunge-test, heel-rises to exhaustion and best of three drop jumps were analysed on the dominat leg. Pearsons correlation was used to evaluate the relationship between My Jump2 and clinical tests and ANCOVA to analyse diffrences within the testgroup. Results: Analysis showed two significant correlations between functional values for the men and one for women when comparing My Jump2 and clinical tests. A significant difference in RSI-value was found between the covariate (sex) (95% CI; 0,01-0,19, p = 0,03) considering 3rep MAX (factor). No significant difference was found in stiffness between the covariate (sex) considering ROM (factor). Conclusion: This study indicates that further research is needed. Analysis shows few significant correlations between My Jump2 and clinical tests. My Jump2 results shows significant values regarding RSI-values considering sex and musclestrenght. This study can not confirm the relationship and correlations between measured values from My Jump2 and clinical testing of lower extremity performance.

O presente trabalho se ocupa das questões relativas à noção de estrutura no escopo teórico da psicanálise de Jacques Lacan (1901-1981), em específico sobre o objeto de estudo definido por estruturas clínicas, segundo a divisão clássica neurose, perversão e psicose. A questão que norteou a pesquisa foi: Como definir a noção de estruturas clínicas na obra lacaniana? Diante da hipótese de permanência teórica do conjunto estrutural na obra de Lacan, o objetivo da tese foi definir as estruturas clínicas por meio da correlação de tais conjuntos com os três registros Real, Simbólico e Imaginário (RSI) e suas escritas topológicas pelos enodamentos possíveis do Nó-borromeano. O método proposto foi estruturado em quatro capítulos: (1) Análise das bordas epistemológicas para o conceito de estrutura em Lacan, desde o estruturalismo, com a linguística com Ferdinand de Saussure (1857-1913) e Roman O. Jakobson (1896-1982), a antropologia com Claude Lévi-Strauss (1908-2009) e a lógica e a matemática com Aristóteles (384 a.c. -322 a.c.), Gottlob Frege (1848 1925) e indicações gerais da topologia; (2) Proposição da noção de estruturas clínicas, a partir das três principais teorias da constituição do sujeito em Lacan, teoria do estádio do espelho (1949 1964), teoria do complexo de édipo (1950-1970) e teoria da alienação (1964 1970), das quais é possível extrair as indicações dos três registros RSI; (3) Desenvolvimento das operações primordiais Bejahung e Verwerfung - de inscrição no campo da linguagem e seus efeitos de retorno em operadores estruturais específicos a cada conjunto, tais quais na divisão ser, sujeito e eu na montagem da estrutura pelo corte significante; (4) Considerações sobre os arranjos particulares definidos por neurose - o efeito do suporte simbólico ao significante, perversão - posição de recobrimento Imaginário do objeto e psicose - a função imaginária de borda para o Real. Portanto, a tese defendida está pautada numa proposição estrutural da subjetividade pela articulação de operações fundamentais de inscrição no campo da linguagem, e de operadores específicos pela amarração dos três registros RSI, escritos nos enodamentos do Nó-Borromeu RSI, que se atualizam sob transferência enquanto hipótese diagnóstica na particularidade de um tratamento / The present work deals with the questions related to the notion of structure in the theoretical scope of the psychoanalysis of Jacques Lacan (1901-1981), specifically on the object of study defined as clinical structures, according to the classic neurosis, perversion and psychosis division. The question that guided the research was: How to define the notion of clinical structures in the Lacanian work? In view of the hypothesis of theoretical permanence of the structural set in Lacan\'s work, the aim of this thesis was to define the clinical structures by means of the correlation of such sets with the three registers Real, Symbolic and Imaginary (RSI) and their topological writings by the possible intertwinement of the Borromean knot. The proposed method is structured in four chapters: (1) Analysis of epistemological edges to the concept of structure in Lacan, from the structuralism, with Linguistics with Ferdinand de Saussure (1857-1913) and Roman O. Jakobson (1896-1982), anthropology with Claude Lévi-Strauss (1908-2009) and logics and mathematics with Aristotle (384 BC-322 BC), Gottlob Frege (1848-1925) as well as General topology; (2) Proposal of the concept of clinical structures, from the three main theories of the constitution of the subject in Lacan, theory of the mirror stage (1949 1964), theory of the Oedipus complex (1950-1970) and theory of alienation (1964-1970), from which it is possible to extract the indications of three registers RSI; (3) The development of main operations - Bejahung and Verwerfung - on the inscription in the field of language and their returning effects on specific structural operators to each set, such as in the division being, subject and I in the assembly of the structure by the signifier cutting; (4) Consideration of the particular arrangements defined as neurosis - the effect in the symbolic support to the signifier, perversion - position of the imaginary object covering and, psychosis - the imaginary function of edge for the Real. Therefore, the thesis defended is based on a structural proposition of subjectivity by the articulation of fundamental operations of inscription in the field of language, and of specific operators in the tying of the three RSI registers, written in the intertwinements of the Node-Borromeo RSI, that are updated under transfer while diagnostic hypothesis in the particularity of a treatment