O gênero Passiflora é um excelente modelo para estudos de transição de fase, pois há diferenças morfológicas evidentes entre as plantas nas fases juvenil, adulta vegetativa e adulta reprodutiva. Há relatos de que quando se introduzem ápices de plantas adultas de Passiflora edulis, quer estejam na fase vegetativa ou reprodutiva, em condições de cultivo in vitro, observa-se a regressão à fase juvenil. O objetivo geral deste trabalho foi caracterizar as modificações morfológicas envolvidas na reversão à juvenilidade de ápices caulinares adultos de P. edulis quando cultivados em meio de cultura sem adição de reguladores de crescimento além de avaliar o efeito de reguladores de crescimento no intuito de evitar a reversão à juvenilidade no cultivo in vitro de P. edulis. O trabalho foi desenvolvido a partir da combinação da técnica da micropropagação in vitro e microscopia eletrônica de varredura, sendo dividido em três experimentos: o cultivo in vitro de ápices caulinares em meio MSM sem reguladores de crescimento e análise de amostras em microscópio eletrônico de varredura, cultivo in vitro de ápices caulinares em meio MSM com reguladores de crescimento e cultivo in vitro de ápices caulinares em meio MSM adicionados com BAP na concentração de 10?M com análises de amostras em microscópio estereoscópico. Através de micrografias eletrônicas e imagens estereoscópicas, foi possível caracterizar as fases do desenvolvimento de P. edulis, demonstrando os caracteres morfológicos assim como a manutenção das estruturas cultivadas in vitro. Não foi possível observar o rejuvenescimento in vitro quando ápices caulinares foram cultivados em meio ½ MS ou MSM sem adição de reguladores de crescimento. O rejuvenescimento de ápices caulinares adultos de P. edulis foi obtido a partir do cultivo em meio MSM com adição de 10?M de BAP. Entretanto, o rejuvenescimento foi parcial, pois nem todas as características foram revertidas. A formação de folhas lanceoladas in vitro e o desenvolvimento de brotos adventícios in vitro caracterizaram a reversão à juvenilidade em P. edulis. O meio MSM suplementado com 10 ?M de BAP foi favorável ao desenvolvimento de gemas axilares, além de facilitar a indução do rejuvenescimento dos ápices caulinares. Logo, a reversão à juvenilidade foi alcançada sob as condições in vitro adotadas / The genus Passiflora is an excellent model for phase transition studies because there are obvious morphological differences between plants in the juvenile, adult vegetative and adult reproductive phases. It has been reported that when introducing shoot tips of adult plants of Passiflora edulis, whether in the vegetative or reproductive phase, under in vitro culture conditions, regression to the juvenile phase is observed. The general objective of this work was to characterize the morphological changes involved in the reversion to juvenility of adult shoot tips of P. edulis when grown in culture medium without addition of growth regulators in addition to evaluating the effect of growth regulators in order to avoid reversion to juvenility in the in vitro cultivation of P. edulis. The work was developed from the combination of in vitro micropropagation and scanning electron microscopy, and was divided in three experiments: in vitro culture of shoot tips in MSM medium without growth regulators and analysis of samples in scanning electron microscope; in vitro culture of shoot tips in MSM medium with growth regulators and in vitro culture of shoot tips in MSM medium added with BAP at the concentration of 10?M and analysis of samples under a stereoscopic microscope. Through electronic micrographs and stereoscopic images, it was possible characterize the phases of the development of P. edulis, demonstrating the morphological traits as well as the maintenance of the structures cultivated in vitro. In vitro rejuvenation could not be observed when shoot tips were grown in ½ MS or MSM medium without addition of growth regulators. The rejuvenation of P. edulis adult shoot tips was obtained from the cultivation in MSM medium with the addition of 10?M BA. However, the rejuvenation was partial, since not all the characteristics were reversed. The formation of in vitro lanceolated leaves and the development of in vitro adventitious shoots characterized the reversion to juvenility in P. edulis. The MSM medium supplemented with 10?M BA was favorable to the development of axillary buds, in addition to facilitating the induction of the rejuvenation of the shoot tips. Therefore, the reversion to juvenility was achieved under the in vitro conditions adopted

The urban landscape reflects the social, economic, and policy changes that have taken place in a community. The inner city has been previosly called a microcosm that indicates the changes that are occurring in society. The inner city can thus be studied to examine how it responds and adapts to economic change. This thesis asks in what ways are the historic and current economic transitions visible in Hamilton’s inner city landscape; and how do planning policies influence the emerging urban built form. The thesis examines select characteristics of the contemporary inner city derived from the literature (i.e. art and entertainment amenitites, recreational uses, residential revitalization, institutional uses, post-Fordist economy, decline in manufacturing activity, promotion of multi-modal transportation, sustainability policy, and statement place making) and their expected physical manifestations. The methods consist of a historical analysis and visual diagnosis that uses photographs and field notes in order to provide a bottom-up interpretation of downtown Hamilton’s changing urban landscape. There is evidence of arts-culture led rejuvenation of downtown Hamilton and the public realm. However, there is the challenge of promoting revitalization in a context of visual urban blight and the possibilities of policy-induced loss of employment lands.

The urban landscape reflects the social, economic, and policy changes that have taken place in a community. The inner city has been previosly called a microcosm that indicates the changes that are occurring in society. The inner city can thus be studied to examine how it responds and adapts to economic change. This thesis asks in what ways are the historic and current economic transitions visible in Hamilton’s inner city landscape; and how do planning policies influence the emerging urban built form. The thesis examines select characteristics of the contemporary inner city derived from the literature (i.e. art and entertainment amenitites, recreational uses, residential revitalization, institutional uses, post-Fordist economy, decline in manufacturing activity, promotion of multi-modal transportation, sustainability policy, and statement place making) and their expected physical manifestations. The methods consist of a historical analysis and visual diagnosis that uses photographs and field notes in order to provide a bottom-up interpretation of downtown Hamilton’s changing urban landscape. There is evidence of arts-culture led rejuvenation of downtown Hamilton and the public realm. However, there is the challenge of promoting revitalization in a context of visual urban blight and the possibilities of policy-induced loss of employment lands.

Cette étude vise caractériser le manteau lithosphérique du massif du Hoggar (Algérie) et son évolution, grâce à une étude multidisciplinaire (pétrologique, géochimique et pétrophysique) d'enclaves mantelliques échantillonnées par le volcanisme cénozoïque. L'échantillonnage provient de deux districts volcaniques (Tahalagha et Manzaz) situés respectivement en périphérie et au coeur du bombement du Hoggar. Le district de Tahalgha est par ailleurs situé à cheval sur un grand cisaillement pan-africain (le 4°35), séparant deux domaines structuraux majeurs du socle du Hoggar : le Hoggar Central Polycyclique à l'Est (domaine LATEA) et le Hoggar occidental à l'Ouest (bloc d'Iskel). Les xénolites étudiés apportent des informations sur l'évolution du manteau lithosphérique depuis l'orogenèse pan-africaine, au cours de laquelle s'est structuré le socle de cette région (le Bouclier Touareg), jusqu'aux événements cénozoïques responsables du bombement topographique et du volcanisme.L'héritage pan-africain est essentiellement préservé dans les échantillons du district périphérique de Tahalgha, sous la forme de lherzolites équilibrées à basse température (750 - 900°C), à clinopyroxènes appauvris en terres rares légères. Ces échantillons sont considérés comme représentant la lithosphère sous-continentale à l'issue des processus de réjuvénation qui ont marqué les derniers stades de l'orogenèse pan-africaine. Ils montrent des textures de déformation (porphyroclastiques à equigranulaires) bien préservées, attribuées à ces événements et caractérisées par des orientations cristallographiques préférentielles (OPRs) de l'olivine (axiales-[010]) compatibles avec un régime transpressif. Les événements cénozoïques sont marqués par un recuit partiel de ces textures, particulièrement prononcé à Manzaz et dans les échantillons de Tahalgha équilibrés à des températures moyennes à élevées (900-1150°C), et affectés par différents degrés de métasomatisme. Les xénolites de Tahalgha représentent un cas d'étude exemplaire du métasomatisme mantellique, couplant variations texturales, minéralogiques et chimiques le long de gradient locaux de température. Une modification des OPRs d'olivine est observée, qui résulterait à la fois de l'infiltration de liquides métasomatiques et d'une réactivation des accidents pan-africains en cisaillement pur.Des implications importantes de cette étude résident dans l'échelle des variations de premier ordre attribuées aux interactions lithosphère-asthénosphère au Cénozoïque. Celles-ci sont essentiellement à l'échelle du bombement du Hoggar (différences entre Manzaz et Tahalga, c'est-à-dire entre Hoggar central et périphérique) ou à celle de conduits magmatiques et de leurs épontes (variabilité locale des xénolites de Tahalgha). Par contre, les résultats obtenus montrent peu de variations significatives pour les échelles intermédiaires, notamment pour des localités de Tahlagha situées de part et d'autre ou à différentes distances du 4°35. Ceci favorise plutôt, pour l'origine du bombement volcanique du Hoggar, les modèles faisant appel à des structures d'assez grande échelle telle qu'un panache mantellique ou une cellule de convection asthénosphérique de type « Edge Driven Convection », plutôt qu'un processus essentiellement lié à la réactivation des failles lithosphériques pan-africaines. / This study aims to characterize the lithospheric mantle of the Hoggar swell (Algeria) and its evolution through time via a multidisciplinary (petrological, geochemical and petrophysical) study of mantle xenoliths sampled by Cenozoic volcanism. The samples were collected in two volcanic districts (Tahalagha and Manzaz) located in the periphery and in the central part of the Hoggar massif, respectively. The Tahalgha sampling also straddles a mega pan-African shear zone (the 4°35 fault) between two major structural domains of the Tuareg Shield basement: the Central Polycyclic Hoggar to the East (LATEA terranes) and the Western Hoggar domain to the West (Iskel block). The studied xenoliths provide information on the evolution of the lithospheric mantle from the Pan-African orogeny – i.e. the period when the Tuareg Shield was structured – to the Cenozoic events responsible for topographic upwelling and volcanism in the Hoggar swell.The Pan-African heritage is found in xenoliths from the peripheral Tahalgha district. These samples are distinguished by low equilibrium temperatures (750-900°C) and LREE-depleted clinopyroxene compositions. They are considered to represent the sub-continental lithosphere after the rejuvenation process that marked the later stages of the Pan-African orogeny. They show well preserved deformation textures (porphyroclastic to equigranular) assigned to these events and characterized by preferential crystallographic orientations (CPOs) of olivine (axial-[010]) consistent with a transpressional regime. The Cenozoic events are marked by partial annealing of these textures, particularly pronounced in the Manzaz samples, as well as in the Tahalgha xenoliths equilibrated at medium to high temperatures (900-1150°C). These samples were affected by different degrees of metasomatism. The Tahalgha xenoliths represent a rather unique case study of mantle metasomatism, where coupled textural, mineralogical and chemical variations occur along local temperature gradients. The Cenozoic events were also responsible for a change in olivine CPOs, resulting from both infiltration of metasomatic fluids and reactivation of Pan-African accidents in a pure-shear regime.Important implications of this study lie in the scale at which the first-order lithosphere modifications ascribed to the Cenozoic event are observed, i.e. either at the scale of the whole Hoggar swell, as shown by the increasing degree of textural annealing and metasomatism from Tahalgha to Manzaz (i.e. from outer to central Hoggar), or at the small scale of magma conduits and their wall rocks, as shown by the local variability registered by the Tahalgha xenoliths. Conversely, our data show little changes at intermediate scales, as might be expected, for instance, among the Tahalgha localities situated on either sides - or at different distances - from the 4°35. As regards the origin of the Hoggar volcanic swell, this result favours the models involving relatively large-scale structures such as a mantle plume or "Edge Driven Convection", rather than a process involving merely the reactivation of pan-African lithospheric faults.

NDLTD Innovative ETD Award 2005. The design of a multi-functional building entails the synthesis of multiple systems and networks. The needs of multiple clients must be effectively overlaid to create a build able, contextually suitable and aesthetically pleasing architectural solution. The proposed building is a public, urban building. City buildings consist of spaces that are essentially part of the city, simultaneously dependant on the whole and separated by building lines and security systems. The gradation of space from public to private exists everywhere. The focus of the design is on the creation of place in the Pretoria CBD. The scheme is integrated into its surroundings, and functions as a system in itself. The proposed multi-use building will be set on a currently built up site in the Pretoria CBD, on the c/o Paul Kruger and Schoeman Streets, one city block from Church Square. Building functions include retail, residential, a satellite gallery for the Tshwane Art Museum, and new offices and facilities for Talking Beads, a producer Arts and Crafts. / Dissertation (MArch (Prof))--University of Pretoria, 2006. / Architecture / unrestricted

Avaliar a biocompatibilidade do fio lifting biológico - fio serrilhado de poliuretana de óleo de mamona - e sua eficácia no rejuvenescimento facial. Na primeira etapa deste trabalho implantamos os fios no dorso de camundongos, que foram sacrificados com 03, 07, 15 e 30 dias com posterior análise histológica por microscopia óptica. Na segunda fase implantamos os fios na face de pacientes com flacidez dérmica e analisamos, fotograficamente e através de uma modelagem numérico-computacional o resultado (rejuvenescimento), com intervalos entre 07 e 60 dias. As análises histológicas demonstraram uma rápida integração do fio ao tecido celular subcutâneo com formação abundante de colágeno e as fotografias dos pacientes revelaram uma maior firmeza da derme e um rejuvenescimento facial, comprovados pela análise computacional. Suas características químicas e físicas e os resultados iniciais nos permitem acreditar que o fio lifting biológico - fio serrilhado de poliuretana do óleo de mamona - apresenta elevada biocompatibilidade com uma rápida integração ao tecido subcutâneo sendo uma excelente opção no rejuvenescimento facial. / Evaluate the biological lifting thread - castor oil polyurethane serrulate thread - bio-compatibility and it´s eficacy on facial rejuvenation. At first we implanted the threads in subcutaneous tissues on mice backs that were sacrificed after 03, 07, 15 and 30 days, followed by histological analysis of material by using optical microscopy. Later, implants were carried out in patients with facial dermal flaccidity, and comparisons were made through photographs between 7 and 60 days, than we made a numerical-computational modelling comparision of this photographs. Histological analysis showed a quick thread integration with the celular subcutaneous tissue by a large amount of colagen syntesis and the patients photographs showed facial rejuvenation with improvement of the skin flaccidity comproved by numerical modelling. It`s chemical and physical characteristics and the initial results allow us belive that the biological lifting thread - castor oil polyurethane serrulate thread - has good bio-compatibility and fast integration with the celular subcutaneous tissue being an excellent option for the facial rejuvenation.

En el Perú existe un mercado en crecimiento ante la necesidad de las mujeres de recuperar su calidad de vida la cual se ve disminuida al presentar problemas tanto funcionales como estéticos en la zona íntima. Para ello se propone la creación de una nueva unidad de negocios en un centro médico en funcionamiento mediante once procedimientos con láser y sin láser aplicado por profesionales calificados . En la investigación de mercado se determinó que el público objetivo son mujeres de edades comprendidas entre 18 y 65 años, residentes en los distritos de Callao, San Miguel, San Martín, Los Olivos, Pueblo Libre y Lima Cercado, de nivel socioeconómico AB, que tengan la necesidad de dar solución a los diferentes problemas de la salud ginecológica, ya sea por el paso del tiempo o injurias externas como por ejemplo el embarazo y parto. En base al estudio de mercado se ha establecido que el potencial de mercado es aproximadamente 8000 mujeres por lo que Medivital espera atender 216 procedimientos y 2160 consultas para el primer año a un precio promedio de 1,200 soles. La inversión inicial será financiada mediante un crédito del 80% de la inversión total ​Los ingresos el primer año para Medivital ascienden a 313,200 soles por lo que el plan de negocios es viable y rentable obteniendo un VAN de 643,203 soles y un TIR de 77% mientras que el VANE fue de 732,360 soles mientras que el TIRE fue de 87.5. / There is a growing market in Peru in view of the women's need to functionally and aesthetically recover the functioning of their private parts. For this purpose, Medivital must create another business unit in an operating medical center with eleven laser and non-laser procedures. The target audiences are women between the ages of 18 and 65, residing in the districts of Callao, San Miguel, San Martin, Los Olivos, Pueblo Libre and Lima Cercado, socioeconomic status AB, who wish to improve their physical appearance, either for deterioration in inclement weather or previous pregnancies. Based on the market study,there are a potencial market from 8000 women. Medivital wish to attend 216 procedures and 2160 consultations for the first year at an average price of 1,200 soles. The initial investment will be financed through a credit of 80% of the total investment . The first year revenues for Medivital amount to 313,200 soles, so the business plan is viable and profitable, obtaining a NPV of 643,203 soles and an IRR of 77%, while the VANE was 732,360 soles while the TIRE was 87.5. / Trabajo de investigación

本研究主要探討日本綜合商社，在面對產業經營環境衝擊下之組織變革因應之道，並選取與台灣電子產業發展關係密切的兼松集團之電子事業為研究探討對象。期以兼松組織變革活化成功的個案，做為台灣企業面臨變革轉型的一參考借鏡。 　　在不景氣的經濟大環境下，商社的價值已改變，且已不再有像以往每年持續成長的榮景，本研究旨在探討兼松電子變革因應之新思維與變革執行之具體做法。兼松在面對變局之際，為使企業保有持續成長之優勢，特採選擇與集中之新思維重整領域。針對現有架構檢討，擬定改革方針並採取最有效的目標管理，具體落實地結合績效考評，因而順利地成功轉型。變革成功經驗，他山之石或可攻錯。兼松轉型活化成功的變革策略，對台灣地區面對成長瓶頸的大型企業，如何藉由結合核心能耐，跨入新興事業領域？或可做為企業經營上之參考借鏡。 　　變革要能有效進行，任何變革策略、改造流程或提昇品質的方法，都必須妥善處理以排除變革的障礙。科特(Kotter)所提成功轉型的八大步驟：1.建立危機意識；2.成立領導團隊；3.提出願景；4.溝通願景；5.授權員工參與；6.創造近程戰果；7.鞏固戰果並再接再厲；8.讓新做法深植企業文化中，很具體的勾勒出變革策略新思維、結構調整與變革執行之做法。本研究發現兼松在落實推動變革執行之後，已成功地變革轉型為：從資訊型物流仲介者到知識型通路整合者；結合核心能耐跨入新興領域；從事業部結構到社內子會社。 　　綜合本研究探討，從兼松的轉型變革成功個案帶給台灣的啟示是：企業唯有經由重新定義的變革再思維，朝相關核心能耐做創新求變，並將變革思維、策略與結構調整三者緊密結合執行，以及培育持續變革的組織文化，才能確保變革轉型成功。 / This research studies the organization restructure in Japanese enterprise while facing the severe impact on business environmental changes. Kanematsu is selected as the research object because of the close business development relationship with Taiwanese electronic industry. The successful rejuvenation of Kanematsu by restructuring the organization can be a typical benchmark for Taiwan in transformation. 　　Under the long time economic recession, the value of the enterprise has been changed, and no more creating the continuous prosperity as usual. This research studies the practical approach that Kanematsu took to execute the transformation of structure through rethinking methodology of change management. By adopting the strategic rethinking of selection and focus, Kanematsu redefined the business to assure the continuous growth for enhancing enterprise's competence toward the changes. Kanematsu's successful transformation experience by implementing restructuring strategy can be a model for Taiwanese enterprise in facing the bottle neck of growth in order to leap into a new business field by integrated the core competence. 　　Kotter's eight steps of transformation: 1. Establish a sense of urgency, 2. Form a powerful guiding coalition, 3. Create a vision, 4. Communicate the change vision, 5. Empower employees for broad-based action, 6. Generate short-term wins, 7. Consolidate gains and producing more change, 8. Anchor new approaches in the culture, specifically outlines the ways of change management's strategic rethinking, re-structuring and executing corporate transformation. Some findings of this research exposure that through practical implementing and executing the transformation, Kanematsu successfully transformed from IT intermediator to informediator; leaped into a new era by congregating the core competency; and transformed from departmental structure to internal subsidiary. 　　What this research reveals can be an inspiration to Taiwanese enterprise in transformation. Only through the rethinking to redefine the business, restructuring to enhance the core competence, executing concurrent transformation thoroughly, and then building up the corporate culture of pursuing the advantage of managing the endless change can lead to successful transformation.

由於許多企業對於LINE在號召年輕族群的能力寄與厚望，為了釐清目前企業對於評估LINE與操作LINE的策略是否合乎年輕族群的需求，本研究將聚焦於討論最早採用LINE的企業期待透過LINE進行品牌年輕化的歷程，以企業的實戰經驗切入，剖析早期採用LINE的企業進行品牌年輕化歷程與操作策略，同時透過釐清年輕族群對於使用LINE的經驗與需求兩相對照，試圖釐清目前企業使用LINE進行品牌年輕化的做法是否正確？是否有迷思存在的可能性？若因迷思存在而造成經營策略上的偏差，企業未來該如何修正與優化？ 由於意會本質上是人們對事務的主觀認知，並且是一個持續性的流程，是一種複雜且動態的觀念，因此將採用深度訪談法針對企業的相關部門成員進行歷程的研究。為呈現企業內部與外在社會環境相關的完整脈絡，本研究也會輔以消費者訪談、文獻資料法與二手資料法作為資訊搜集與驗證成效的方式。研究結果發現，個案對於透過LINE推動品牌年輕化的歷程上，確實存有許多囿於過往經驗或組織文化所形成的主觀認知，導致其對於新科技的理解與其目標族群的需求有所落差。研究結果也顯示，LINE確實能為企業接觸到年輕族群，但需要提供他們所需要的服務和資訊，才能爭取他們對品牌的認同和好感，同時與年輕族群的互動形式，相較於過往的單向式傳播，也必須因應LINE的科技特質有所調整。 / As many enterprises place great expectations in LINE’s ability to call out the youth, in order to find out whether the enterprises’ strategies in assessment and operation on LINE meeting the demand of the youth, this research looks into the experience of the first runner enterprises that promote brand rejuvenation with LINE. By introducing the real-world experience of the enterprise, this research analyzes the journey and operation strategies of rejuvenating brands by using LINE in early years. Meanwhile, by comparing the experiences and demand of using LINE among the youth, this research aims at whether the methods of rejuvenating brands by using LINE are satisfying. Does the myth really exist? If the myth does exist and bring diversified business strategies, how can the enterprises revise and improve their strategies in the future? Since sense making is people’s subjective perception of affairs by nature and it is both a persistent process and a complicated and dynamic concept, this research focuses on the experience from members of relevant departments of the enterprise by in-depth interview. To present the context of the internal and external environment of the enterprise, this research also utilizes consumer interview, documents, and literature as the main data sourses and effectiveness verification. The research results show that cases do have many subject perceptions generated from previous confined experience or organizational culture in the course of LINE’s promotion of brand rejuvenation, which gives rise to difference between the understanding of new technology and the demand of target groups. The research results also show that LINE really enables the enterprise to access to the young people, but provision of their necessary service and information is required to get their recognition and good impression of the brand. Meanwhile, the means of interaction with the youth must be adjusted according to LINE’s technological nature comparing with previous single-direction dissemination.

No description available.