<p>The aim of this essay is to study and show the contents of the music repertoire that is used in live action role plays in Sweden and study how this repertoire is spread between participants in the culture of live action role playing.</p><p>Four informants have been chosen and interviewed, three men and one woman of different ages from different places in Sweden. They have all been practicing live action role playing for some years.</p><p>Some of the conclusions that can be drawn from this study is that the participants of this hobby culture value music that feels old and contribute to the illusion of another world and time. The music repertoire of the live action role playing culture is filled with this music that gives the participants associations in line with the illusion. That is more important than the real age of the music. Another interesting conclusion is that the participants learn and spread the melodies verbally to each other and only the texts spread on the internet.</p>

<p>This study is based on my work as a teacher of Swedish language and literature to upper secondary school students, and my interest in developing the teaching of literature by using both new criticism theories and theories of literary perception focusing on reader response. The purpose of the study is to examine the learning process in trying to develop literary competence and to find out how to describe the competence shown by the students. My starting-point is a discussion about literary competence and the theory and model of literary competence by Örjan Torell. In examining literary competence, by how students use their constitutional competence as well as performance and literary transfer competences, Torell´s model shows the possibility and the need for both knowledge of literature and personal reception by focusing on the dialogue between author and reader.</p><p>The method is qualitative and the empirics are material collected in one senior high school class in the Social Science programme during their second and third year. The material contains written reading logs, written answers to tasks and transcribed recordings of discussions of literature.</p><p>The analysis shows a variety among the literary competence shown and developed by the students and points to the complexity of understanding the concept of literary competence. The model proves to be useful in focusing the teaching and learning of literature and the results indicate that teaching of literature by combining learning of epochs, genres, ideas and conceptions with personal reading is a valuable approach.</p><p>Keywords: literary competence, literary teaching, literary reception, discussions of literature, reading logs, literary repertoire, text competence.</p>

Antibodies are essential molecules that help to provide immunity against a vast population of environmental pathogens. This antibody conferred protection is dependent upon genetic diversification mechanisms that produce an impressive repertoire of lymphocytes expressing unique B-cell receptors. The advent of high throughput sequencing has enabled researchers to sequence populations of B-cell receptors at an unprecedented depth. Such investigations can be used to expand our understanding of mechanistic processes governing adaptive immunity, characterization of immunity related disorders, and the discovery of antibodies specific to antigens of interest. However, next generation sequencing of immunological repertoires is not without its challenges. For example, it is especially difficult to identify biologically relevant features within large datasets. Additionally, within the immunology community, there is a severe lack of standardized and easily accessible bioinformatics analysis pipelines. In this work, we present methods which address many of these concerns. First, we present robust statistical methods for the comparison of immunoglobulin repertoires. Specifically, we quantified the overlap between the antibody heavy chain variable domain (V H ) repertoire of antibody secreting plasma cells isolated from the bone marrow, lymph nodes, and spleen lymphoid tissues of immunized mice. Statistical analysis showed significantly more overlap between the bone marrow and spleen VH repertoires as compared to the lymph node repertoires. Moreover, we identified and synthesized antigen-specific antibodies from the repertoire of a mouse that showed a convergence of highly frequent VH sequences in all three tissues. Second, we introduce a novel algorithm for the rapid and accurate alignment of VH sequences to their respective germline genes. Our tests show that gene assignments reported from this algorithm were more than 99% identical to assignments determined using the well-validated IMGT software, and yet the algorithm is five times faster than an IgBlast based analysis. Finally, in an effort to introduce methods for the standardization, transparency, and replication of future repertoire studies, we have built a cloud-based pipeline of bioinformatics tools specific to immunoglobulin repertoire studies. These tools provide solutions for data curation and long-term storage of immunological sequencing data in a database, annotation of sequences with biologically relevant features, and analysis of repertoire experiments. / text

The purpose of this research is to create an awareness of the significant contributions to the solo and chamber trumpet literature made by Jiří Laburda (b. 1931), a twentieth-century composer from the Czech Republic. Laburda has an extensive oeuvre including 22 solo pieces for trumpet and accompaniment, four pieces for two or more trumpets, two collections of trumpet duets, eight brass chamber works including at least one trumpet, and six works for brass quintet. Select pieces by Laburda for trumpet and piano lend themselves to pedagogical uses for the instruction of beginning and intermediate trumpet students, and thus provide a valuable repertory of teaching pieces that could help prepare students to play standard repertory such as the Haydn and Hummel concerti for trumpet. This document provides annotated pedagogical analyses of four compositions by Jiří Laburda including Diarium (a five-volume set of short technical studies for trumpet and piano), Peter with Trumpet, Sonatina for Trumpet, and Sonata for Trumpet. The four works have been selected from various levels of difficulty to illustrate Laburda's method of sequential progression in writing for different stages of the developing trumpet student. Each analysis explains how the composition is of particular value for trumpet students and for what purpose(s) the piece can be used pedagogically. The analyses contain various exercises and suggestions to help students practice and prepare these pieces for performance.

This study examines negative issues that cannabis users have experienced associated with cannabis use. The author made qualitative interviewsto unveil four cannabis users’ life stories. These stories were analyzed through the discourse psychologicalperspective interpretive repertoirein order to explore and identify analogies among the users. The author found that the respondents, despite their seemingly diverse backgrounds and personalities, carry a collective repertoire of similar experience and reasoning around cannabis and society which can be defined as a cannabis discourse; a discourse grounded in facts as well as speculations, arguments which separately may seem reasonable but altogether often appear contradictory, and real-life anecdotes that sometimes reflect paradoxical conclusions. It's suggested that the respondents, through their repertoire, construct and maintain this discourse while social stigma and legal retaliation strengthens it. These findings may be useful for social workers in order to understand cannabis users’ situation, societal vulnerability and sometimes controversial values, including the origins of such.

Song repertoire structure, organization, and use were studied in 68 male Canada Warblers (Cardellina canadensis) in a breeding population in New Hampshire in 2010-2011. On average, males had complex repertoires of 12 phrases and 55 variants. Repertoire sharing was negatively related to distance between territories, and positively related to longer territory tenure, evidence that males learn songs from neighbours. Males used two singing modes: (I) slow, regular delivery of less variable songs, and (II) fast, intermittent delivery of more variable songs interspersed with chips. Males used Mode I when unpaired and when near females, and Mode II at dawn and during territory disputes, a pattern similar to other warbler species with two song categories. Detectability (whether a male sang) differed little between 1-, 3-, 5-, and 10-min count intervals. Song output and detectability were highest at dawn and in unpaired males, and lowest in paired males late in the season.

This thesis begins with the claim that gendered violence continues to plague First Nations women and Aboriginal communities across Canada, despite national statistics that suggest improvement. Contemporary Native theatre attempts to counter systemic violence that oppress the Aboriginal peoples. Violence against women is especially prevalent when exploring First Nations realities, and the dramatic works examined illustrate how the rampancy of gendered violence both hinders and defines the lived realities of First Nations women in Canada. Through the careful reading of Tomson Highway’s The Rez Sisters, Yvette Nolan’s Annie Mae’s Movement, and Marie Clements’s The Unnatural and Accidental Women this thesis contends that Native theatre is an affective tool for promoting social change. Through witnessing and testifying, seeking spiritual and cultural fulfillment, and exploring the potentialities of what I call the Aboriginal repertoire, First Nations women and Canada as a nation may take the next steps toward individual and communal wellness.

The B cell repertoire in the neonatal immune system (IS) is characterised by reactivity towards self-components, including other immunoglobulin (Ig) V-regions. These properties have been suggested to be a requirement for the development of a normal immune system. DNA sequencing of two interacting Ig idiotypes, derived from neonatal, preimmune mice, demonstrated that such idiotypic connectivity is germ- line encoded and devoid of VDJ junctional diversity. The serum levels of the same Ig idiotypes were studied in normal mice and demonstrated that the expression in serum fluctuated over time in a pattern compatible with a complex dynamic system. In contrast, similar analyses in autoimmune mice or humans demonstrated fluctuations in Ig titers that differed significantly from the healthy individuals. These findings suggested that pathological autoimmunity may be associated with fundamental alterations in the dynamics of natural antibody (ab) expression. This was further investigated in the nonobese diabetic (NOD) mouse, an animal model for human Type I diabetes. Suppression of the early B cell development in the NOD mouse prevented the development of diabetes, suggesting a role for B cells/Igs in the development of diabetes in these mice. Furthermore, neonatal injections of polyclonal Ig preparations or single, monoclonal natural abs inhibited disease induction. The prevention of diabetes development by one such natural ab was demonstrated to be dependent on both the dose injected and the timing of administration. Studies of the B cell repertoire development in NOD mice, compared to normal mice, by DNA-sequence analyses of IgVH rearrangements utilising genes from the most D-proximal Vh family, Vh7183, supported the idea of an aberrant B cell repertoire in this mouse model. Thus, the adult NOD mouse retained a neonatal pattern of Vh7183 rearrangements. This pattern could, however, be "normalised" by neonatal injection of a natural antibody, previously demonstrated to prevent the development of T cell dependent autoimmunity in the NOD mouse. / <p>Diss. (sammanfattning) Umeå : Umeå universitet, 1993, härtill 6 uppsatser</p> / digitalisering@umu

The focus of this thesis is how identities are construed in adult education. According to the theoretical framework inspiring the study, identities are viewed as discursive constructions that are negotiated in social arenas. Hence, identities are considered versatile, plural and contradictory. The study has an ethnographic case study design and the field work was conducted 1998–2001. Various sources of data collection, such as interviews and participant observations were utilised. Every day practice at three different institutions of adult education in the case study municipality ”Nystad” were studied: Folk high school, Komvux and Liber Hermods flexgymnasium. Participants (27) were studied extensively, and a follow-up containing biographical interviews with the participants was also done 18 months after the main study. The result will show how the discourse of life long learning produce different technologies applying to different institutions of adult education defining what counts as knowledge, the relationships between actors and the demands participants will be posed with. Although the institutions of education are different, there are also similarities. The differences, however, are important in the recruitment of participants. The requirements of the education as to who you are supposed to be as a participant in adult education show a similar pattern, irrespective of the institution of education; the student with an interest in studying, prone to change, independent and well-behaved. Different strategies are detected when focusing the staging of participants’ identities, adaptive and defiant. An adaptive strategy means the adults meet the requirements of the education and a defiant strategy that they resist. The strategies may be applied by one and the same participant depending on the situation. Biographies show how different interpretative repertoires are used to stage different identities. The participants use four repertoires relevant to the subject: that of making a living, learning, earning credits and self realization. The repertoires applicable to the forms of teaching are teacher oriented, selfdirected and conversational. The repertoires used in relation to the teachers in adult education are expert, person, supervisor and administrator. The repertoires used by the adults in order to describe other participants are adult student, study mate and friend. The result of the study inspires the discussion of adult education in terms of social inclusion and exclusion.

La diversité génétique du virus de l'immunodéficience humaine, le VIH-1 responsable de la pandémie du SIDA, représente un challenge dans le développement d'un vaccin qui doit conférer une protection contre différentes formes du virus pour être efficace. L'identification de populations de lymphocytes T CD8+ (CTL) capables de reconnaître des variants peptidiques d'un épitope est donc une étape importante. Dans le modèle singes rhésus, j'ai montré en utilisant des tétramères spécifiques de 9 variants peptidiques d'un épitope qu'une même population de CTL générés par la vaccination, peut reconnaître l'épitope relatif à l'immunogène et un certain nombre de ses variants provenant de diverses formes du VIH-1. Ces études ont également permis de caractériser les populations de CTL spécifiques de chaque variant de cet épitope en analysant l'expression des différents gènes codant pour la chaîne variable β du TCR (Vβ répertoire) et par un large séquençage des régions complémentaires déterminantes 3 (CDR3) du TCRβ. Ces travaux ont montré qu'une vaccination utilisant la séquence du clade C de l'enveloppe du VIH-1 conduit à des réponses divergentes chez 2 singes rhésus Mamu-A*01+. De plus, ces résultats ont mis en évidence que l'usage de certainβes nVe permet pas de déterminer le potentiel cross-réactif des CTL. Par ailleurs, une immunisation utilisant des séquences de l'enveloppe du clade B du VIH-1 peut générer des CTL capables de reconnaître un large nombre de variants de l'épitope testé. L'analyse de 8112 séquences CDR3 du TCRβ a permis de les caractériser. Cependant, les tests fonctionnels ont démontré que bon nombre de ces variants peptidiques stimulent une production suboptimale de cytokines par les CTL générés après vaccination. Ces résultats démontrent que la reconnaissance de variant peptidiques d'un épitope est nécessaire mais pas suffisante pour protéger contre différentes formes du VIH-1 exprimant ces séquences. L'identification de variants peptidiques capables d'induire une réponse fonctionnelle des CTL pourrait contribuer au développement d'un vaccin efficace contre le VIH-1.