Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-02-15T13:45:21Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Adriane Cardim 2015.pdf: 1719203 bytes, checksum: 5820b852957920840a3967619c38ee97 (MD5) / Made available in DSpace on 2017-02-15T13:45:21Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Adriane Cardim 2015.pdf: 1719203 bytes, checksum: 5820b852957920840a3967619c38ee97 (MD5) Previous issue date: 2015-08-20 / CAPES / A doença pulmonar obstrutiva crônica (DPOC) é uma desordem respiratória associada à disfunção muscular esquelética e ao desenvolvimento de hiperinsuflação pulmonar o que contribui para dispneia e redução da tolerância ao exercício. O alongamento dos músculos da caixa torácica e a vibração de corpo inteiro surgem como terapias alternativas para recuperar a função muscular e melhorar a capacidade funcional. Os objetivos desta dissertação foram: 1. Avaliar os efeitos agudos de um programa de alongamentos da musculatura da caixa torácica sobre a mobilidade diafragmática e a cinemática toracoabdominal de pacientes com DPOC durante o exercício; 2. Avaliar a qualidade da evidência da literatura dos efeitos da vibração de corpo inteiro (VCI) sobre a capacidade funcional de pacientes com DPOC. Foi realizado um ensaio clínico composto por 14 pacientes com DPOC, 6 hiperinsufladores severos (HS) e 8 não hiperinsufladores (NH). Os pacientes foram divididos em dois grupos: Alongamento (GA) e Controle (GC) e tiveram avaliadas a mobilidade diafragmática bem como o padrão ventilatório e os volumes da parede torácica antes da intervenção (GA ou GC) e após exercício de carga constante em bicicleta ergométrica. Os resultados mostraram aumentos no volume corrente abdominal (p<0,001), mobilidade diafragmática (p=0,030), além de maiores valores de saturação periférica de oxigênio (p=0,024) no GA em relação ao GC nos pacientes com HS; e redução da frequência respiratória (p=0,023), aumento do volume inspiratório final (p=0,004) e menor sensação de fadiga de membros inferiores (p=0,043) no GA em relação ao GC nos pacientes NH. A sessão de alongamentos não foi capaz de aumentar a tolerância ao exercício. Também foi desenvolvida uma revisão sistemática e metanálise que incluiu quatro artigos envolvendo 185 pacientes, todos os estudos mostraram aumento na distância percorrida no teste de caminhada de seis minutos no grupo com VCI em relação ao controle (57,85 m; IC 95% 16,33-99,33). A qualidade da evidência foi moderada. Concluímos que o alongamento dos músculos da caixa torácica pode trazer benefícios agudos para os pacientes com DPOC, principalmente naqueles que apresentam hiperinsuflação dinâmica severa e que a vibração de corpo inteiro é capaz de melhorar a capacidade funcional de pacientes com DPOC. / Chronic obstructive pulmonary disease (COPD) is a respiratory disorder associated with skeletal muscle dysfunction and the development of lung hyperinflation which contributes to dyspnea and reduced exercise tolerance. Stretching the muscles of the rib cage and the whole body vibration emerge as alternative therapies to restore muscle function and improve functional capacity. The objectives of this study were: 1. To assess the acute effects of a stretching program for the muscles of the rib cage on the diaphragmatic motion and kinematics thoracoabdominal patients with COPD during exercise; 2. To assess the quality of evidence from the literature of the effects of whole body vibration (WBV) on the functional capacity of patients with COPD. It conducted a clinical trial comprising 14 patients with COPD, 6 severe hyperinflators (SH) and 8 non hyperinflators (NH). Patients were divided into two groups: Stretching (SG) and control (CG) and were evaluated diaphragmatic mobility and the ventilatory pattern and volume of the chest wall before the intervention (SG or CG) and after constant load exercise bicycle exercise. The results showed increases in abdominal tidal volume (p <0.001), diaphragmatic mobility (p = 0.030), as well as higher peripheral oxygen saturation values (p = 0.024) in SG than the CG in patients with SH; and reduced respiratory rate (p = 0.023), increased end-inspiratory volume (p = 0.004) and less sense of fatigue of the lower limbs (p = 0.043) in SG than the CG in NH patients. The stretching session was not able to increase exercise tolerance. It was also developed a systematic review and meta-analysis that included four articles involving 185 patients, all studies showed an increase in the distance covered on the six-minute walk test in the group with VCI compared to the control (57.85 m; 95% CI 16.33 to 99.33). The quality of evidence was moderate. We conclude that the stretching of the muscles of the rib cage can bring benefits for acute COPD patients, particularly those with severe dynamic hyperinflation and the whole-body vibration can improve the functional capacity of patients with COPD.

Orientador: Edson Rosa Pimentel / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia / Made available in DSpace on 2018-08-10T19:16:40Z (GMT). No. of bitstreams: 1 Aro_AndreaAparecidade_M.pdf: 2216863 bytes, checksum: ab5348a9628ee1b1c771905a93337915 (MD5) Previous issue date: 2008 / Resumo: Músculos, tendões e ligamentos constituem a maioria das estruturas afetadas durante a realização de atividades desportivas, assim um melhor conhecimento sobre essas estruturas é de grande interesse para profissionais que tratam da reabilitação. Pouco se sabe sobre os efeitos do alongamento sobre aspectos bioquímicos e estruturais de tendões, quando usado como modalidade terapêutica após longo período de imobilização. No presente estudo, com o objetivo de avaliar a resposta do tecido frente a procedimentos de alongamento após imobilização, ratos wistar foram divididos em cinco grupos experimentais: controle do grupo Imobilizado (ratos não imobilizados), grupo Imobilizado (ratos imobilizados por 4 semanas), controle do grupo Imobilizado Alongado e Imobilizado Livre (ratos sem imobilização e alongamento), grupo Imobilizado e Alongado (imobilizados por 4 semanas e alongados durante 3 semanas) e grupo Imobilizado e Livre (imobilizados por 4 semanas e livres na gaiola por 3 semanas). Os tendões foram retirados e separados em regiões proximal (tensão) e distal (compressão) para serem analisados. Para as análises bioquímicas as regiões distal e proximal foram extraídas com cloreto de guanidina e os extratos analisados por SDS-PAGE, dosagem de proteínas não colagênicas e glicosaminoglicanos (GAGs) sulfatados. Para quantificação de hidroxiprolina os tendões foram hidrolisados em HCl. Para as análises morfológicas os cortes de tendões foram corados com Hematoxilina-eosina (HE), Azul de Toluidina (AT) e Ponceau SS (PSS). A análise em SDS-PAGE não mostrou diferenças marcantes entre os grupos, mas uma banda de colágeno mais proeminente foi observada no grupo IL em relação ao IA e ao grupo controle na região de compressão. A dosagem de hidroxiprolina mostrou maior concentração no grupo I na região de compressão. Nenhuma diferença foi observada na região de tensão. Com relação à concentração de proteínas não colagênicas, foram detectadas diferenças apenas na região de tensão, com maiores concentrações no grupo I. Quando comparados os grupos IA e IL, valores mais altos foram encontrados no grupo IA. Foi observado presença abundante de GAGs sulfatados, especialmente de condroitim sulfato, na região de compressão do grupo IA. A presença de dermatam sulfato foi marcante nas regiões de compressão e tensão dos grupos I e IL. A análise em microscopia de polarização de cortes corados com PSS indicou maior desorganização dos feixes de colágeno no grupo I, com parcial recuperação após alongamento ou apenas remobilização. Uma revisão no procedimento de alongamento deveria ser considerada em experimentos futuros, considerando a duração e periodicidade das sessões, visando melhorar sua eficiência em casos de tendões previamente imobilizados / Abstract: Muscles, tendons and ligaments are present in most of structures that may be injured during sportive activities, so a better knowledge on these structures is very important for professionals who work with rehabilitation. Little is known about the stretching effects on the biochemical and morphological features of the tendons, specially when tendons are submitted to a long period of immobilization. In the present work our purpose was evaluate the response of the tissue to the procedures of stretching followed of immobilization, rats wistar were divided into five experimental groups: control Immobilized (rats not immobilized), Immobilized (immobilized for 4 weeks), control Immobilized and Stretched / Immobilized and Free (rats without immobilization and stretching), Immobilized and Stretched (immobilized for 4 weeks and stretched during 3 weeks) and Immobilized and Free (immobilized for 4 weeks and free in the cages for 3 weeks). The tendons were removed and the proximal (tension) and distal (compression) regions were separated to be analyzed. For biochemical analysis the proximal and distal regions were extracted with guanidinium chloride and the extract analyzed for SDS-PAGE, non-collagenous proteins, and sulfated glycosaminoglycan (GAGs sulfated). For quantitation of hydroxyproline the tendons were hydrolysed in HCl. For morphological analysis the sections of the tendons were stained with Haematoxylin-eosin (HE), Toluidine Blue (AT) and Ponceau SS (PSS). Observations were with polarization microscopy. Analysis in SDS-PAGE showed no remarkable differences amongst the groups, but a more prominent band of collagen was observed in the IF in relation to IA and control groups in the compression region. Analysis of the quantity of hydroxyproline showed more concentration in the I group in the compression region. No differences were observed in tension region. With respect to the concentration of non-collagenous proteins, differences were detected only in the tension region, where larger concentrations were found in the I Group. When IS and IF were compared, highest values were found in the IS group. A more abundant presence of sulfated GAGs, especially chondroitin sulfate, was found in the compression region of the IS group. The presence of dermatan sulfate was remarkable in the compression and tension regions of I and IF groups. Analysis of sections stained with Ponceau SS, under polarization microscopy, indicated that the I group exhibits a larger disorganization of the collagen bundles, partially recovered after stretching or with only remobilization. A revision in the stretching procedure should be considered in future experiments, in terms of duration and periodicity of the sessions to try improving the efficiency of the stretching in cases of previous immobilization of tendons / Mestrado / Biologia Celular / Mestre em Biologia Celular e Estrutural

Orientador: Gustavo Luis Gutierrez / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação Física / Made available in DSpace on 2018-08-24T18:30:11Z (GMT). No. of bitstreams: 1 Bastos_RicardoLima_M.pdf: 1078867 bytes, checksum: f1830fc7b4436a9a96c187bab163cbaf (MD5) Previous issue date: 2013 / Resumo: A ginástica laboral é um recurso empregado por empresas de diversos setores para reduzir o absenteísmo, quadro de lesões e melhorar a qualidade de vida de seus funcionários. A lei de cota para deficientes nas empresas foi um importante avanço no processo de inclusão dos mesmos em sociedade. Agora nas empresas este grupo participa das aulas de ginástica laboral, porém, devido a suas particularidades necessitam de um trabalho específico e muitas vezes individualizado por parte dos professores. Entendemos que é de suma importância aprofundar os conhecimentos sobre o tema para que os profissionais melhorar a qualidade de vida destes sujeitos. Objetivamos com o presente, familiarizar estes professores sobre as deficiências e suas particularidades, o ambiente corporativo e a ginástica laboral, bem como, propor contribuições para as aulas deste grupo tanto de ordem técnica como prescrição e execução dos exercícios além da didática durante as aulas / Abstract: The gymnastics is a resource used by companies from various sectors to reduce absenteeism, injuries and improve the quality of life of its employees. The quota law for disabled persons in the companies was a major breakthrough in their inclusion in society. Now in the companies this group participates in gymnastics classes, however, due to its special need for a specific work and often individualized by teachers. We believe it is extremely important to increase knowledge of the subject for professionals to improve the quality of life of these subjects. We aim with this, familiarize these teachers about disabilities and their particularities, the corporate environment and gymnastics, as well as to consider contributions to the lessons of this group both technical as prescription and delivery of exercises besides teaching during lessons / Mestrado / Atividade Fisica Adaptada / Mestre em Educação Física

M.Tech. / Dancing, over the years has become a highly competitive sport with demanding levels of fitness and flexibility needed in order to progress to a professional level (DeMann, 1997). With lower back pain becoming a common occurrence in dancers, both physical as well as emotional stress is placed on the dancer and their lower back (DeMann, 1997). The aim of this study was to compare the effectiveness of Chiropractic adjustments on the lumbar spine and Sacroiliac joints, stretching certain muscle groups or the combination of the two treatment protocols on Freestyle dancers with chronic lower back pain with regards to pain, disability and lumbar spine and pelvis range of motion. Thirty female participants between the ages of thirteen and twenty five years were recruited to participate in this study. Successful participants were then randomly placed into one of three groups, of ten participants each, which would receive different treatment protocols according to their group allocation. Group 1 underwent Chiropractic adjustments to the lumbar spine and Sacroiliac joints, Group 2 received stretching exercises to the Quadratus lumborum muscle; gluteal muscles consisting of Gluteus maximus, medius and minimus; Piriformis; Psoas; Hamstring and Multifidus muscles only and Group 3 received a combination of the treatment protocols. Participants in all three groups were assessed using the Numerical Pain Rating Scale and the Roland-Morris Disability Questionnaire for subjective readings; the Digital Inclinometer was used for objective readings of ROM. All treatments were performed at the Riviere Academy of Dance under the supervision of a qualified Chiropractor. The results concluded that the benefits of an adjustment alone, stretching alone as well as the two treatments combined showed a reduction of pain and increase of ROM, when managing a dancer with lower back pain. Not one treatment was shown to be more beneficial than the other.

A thesis presented in partial compliance wnh the requirements for the Master's Degree in Chiropractic, Technikon Natal, 1999. / Sacroiliac syndrome is a common condition causing low back pain (Mierau et al. 1984, Guo and Zhao 1994). It is a painful, debilitating condition that may cause considerable discomfort (Haldeman 1992:220). According to Frymoyer et al. (1991:2114), sacroiliac syndrome is a frequently overlooked source of low back pain as it may mimic other well known causes of low back pain / M

In order to explore the N-H stretching region of aliphatic amines, we performed a study of the Raman spectrum of n-propylamine at various concentrations in cyclohexane. Statistical analysis provided evidence of a second symmetric stretching vibration, which we were able to assign to nonhydrogen bonded NH2 groups. To obtain additional evidence on the existence of monomers in n-propylamine and to further study hydrogen bonding and Fermi resonance in aliphatic amines, we extended the investigation to the analysis of the Raman spectrum of this compound over an extended range of temperature in the neat liquid phase. This study corroborated our finding that the peak previously assigned to the symmetric stretching mode of hydrogen bonded amines is actually composed of two bands. Furthermore, trends in both the resolved band parameters and the Fermi resonance analysis were tabulated, allowing one to monitor the change in the N-H valence region with concentration and temperature.

Le cartilage articulaire est un tissu conjonctif spécialisé recouvrant les surfaces osseuses et assurant, avec d’autres tissus comme la membrane synoviale, le bon fonctionnement des articulations. Le cartilage est composé d'un type cellulaire, le chondrocyte, qui assure la synthèse et la dégradation d’une matrice extracellulaire essentielle à ses propriétés mécaniques. Les articulations, en conditions physiologique et pathologique, sont soumises à deux stress principaux agissant sur l’homéostasie du cartilage : le stress mécanique et le stress inflammatoire. Le premier objectif de ma thèse était d’étudier l’effet d’un stress mécanique de type étirement sur le profil d’expression des gènes dans des chondrocytes articulaires de lapin en culture primaire en utilisant une approche à grande échelle (micro‐arrays). Nous avons identifié 36 et 57 transcrits répertoriés dans le génome de lapin et dont les taux d’expression sont respectivement augmentés et diminués par un étirement équibiaxial cyclique (5%, 1Hz, 20h). Certains gènes sont connus pour leur implication dans l’inflammation, la mort cellulaire et la dégradation matricielle. Parmi eux, celui de la relaxine (RLN) était le gène le plus induit par l’étirement. La relaxine, hormone peptidique de la superfamille de l’insuline/relaxine, est connue pour son implication dans la reproduction et la grossesse. En revanche son rôle dans le cartilage articulaire restait à étudier. Le deuxième objectif de ma thèse était, par conséquent, de caractériser la fonction de la RLN dans le cartilage. Mes résultats de RT‐PCR quantitative montrent pour la première fois que la quantité des transcrits de la RLN est augmentée par le stress mécanique et le stress inflammatoire (traitement par l’interleukine‐1) dans des chondrocytes articulaires de lapin. De plus, la quantité des transcrits de la RLN est diminuée au cours de la dédifférenciation des chondrocytes. Dans un modèle de gonarthrose induite chez la souris par déstabilisation du ménisque médial, j’ai montré par immunofluorescence que la RLN est principalement présente au niveau des couches superficielles du cartilage de genou et que son expression diminue dans le cartilage arthrosique par rapport au cartilage normal. De plus, le traitement par de la RLN de chondrocytes de lapin augmente l’activité de la métalloprotéinase MMP‐9 impliquées dans la dégradation du cartilage. En conclusion, cette étude montre que la RLN est sensible aux stress mécanique et inflammatoire et la dédifférenciation des chondrocytes. Elle suggère que cette hormone pourrait moduler l’homéostasie du cartilage. La RLN est donc une cible potentielle d’intérêt dans les pathologies ostéoarticulaires. / The articular cartilage is a specialized conjunctive tissue covering bone surfaces. It ensures, together with other tissues like the synovial membrane, the right functioning of the articulations. The cartilage is formed of one cellular type, the chondrocyte, which is responsible for the synthesis and degradation of the extracellular matrix required for its mechanical properties. The joints, under physiological and pathological conditions, are subjected to two main types of stress that affect cartilage homeostasis: mechanical stress and inflammatory stress. The first objective of my PhD thesisis is to study the effect of stretching, one type of mechanical stress, on the gene expression profile in rabbit articular chondrocytes in culture using a large scale approach (micro‐arrays). 36 and 57 transcripts of the rabbit genome which are up‐regulated and down‐regulated by equibiaxial cyclic tensile stretching (5%, 1Hz, 20h) respectively were identified. Some of these genes are known for their implication in inflammation, cell death and matrix degradation. Among them, the relaxin (RLN) gene is the most induced by stretching. RLN is a peptide hormone that belongs to the insulin/relaxin superfamily. It is known for its implication in reproduction and pregnancy. However, the role of RLN in cartilage is still to be studied. The second objective of my PhD thesis is, consequently, to characterize the function of RLN in cartilage. My qRT‐PCR results show, for the first time, that the RLN transcript levels increase upon mechanical and inflammatory (interleukin ‐1treatment) stress in rabbit articular chondrocytes. Moreover, RLN transcript levels decrease during cell dedifferentiation. In a model of gonarthrosis induced in mice by destabilization of the medial meniscus, I showed by immunofluorescence that RLN is mainly present in the superficial layers of the knee cartilage and that its expression decreases in osteoarthritic cartilage as compared to normal cartilage. Furthermore, treatment of rabbit chondrocytes with RLN increases the activity of the metalloproteinase MMP‐9 involved in cartilage degradation. In conclusion, this study shows that RLN is sensitive to mechanical and inflammatory stress and to chondrocyte dedifferentiation. It also suggests that this hormone could modulate cartilage homeostasis. Therefore, RLN is a potential target in osteoarticular pathologies.

Background: Spasticity of the ankle can occur in multiple sclerosis and stroke, and can significantly reduce quality of life by impeding walking and other activities of daily living. Robot driven continuous passive motion (CPM) of the ankle may be a beneficial rehabilitation strategy for lower limb spasticity management, but, objective measures of decreased spasticity and improved locomotion remains uncertain. Additionally, the acute and chronic effects of CPM on spinal cord excitability are unknown. Objectives: To evaluate: 1) the acute changes in spinal cord excitability induced by 30 min of CPM at the ankle joint, in neurologically intact individuals and in those with lower limb spasticity; and, 2) chronic training-induced effects of 6 weeks of bilateral CPM training on reflex excitability and locomotion in those with lower limb spasticity. Methods: Spinal cord excitability was assessed using Hoffmann (H-) reflex recruitment curves, collected immediately before and following 30 min of CPM of the right (neurologically intact) or more affected (clinical) ankle. A multiple baseline repeated measures study design was used to assess changes following 18 bilateral CPM training sessions. Spasticity and locomotion were assessed using the Modified Ashworth Scale, the 10 m Walk test, and the Timed Up and Go test. Results: Twenty-one neurologically intact (6 female, 15 male, mean age 24.5 ± 1.7y) and 9 participants with spasticity (3 female, 6 male, mean age 58.9 ± 9.7y) due to various neurological conditions including stroke (n=4), MS (n=3), spinal cord injury (n=1), and cerebral palsy (n=1). In the neurologically intact group, CPM produced a bi-directional modulation of H-reflex creating ‘facilitation’ (n=12) (31.4 ± 20.9% increase in H-reflex amplitude) and ‘suppression’ (n=9) (32.9 ± 21.0% decrease in H-reflex amplitude) groups. In the clinical participants, acute CPM before training significantly increased H-reflex recruitment curve variables H@Thres and H@50; but there was no significant effect of acute CPM post-training. Baseline reflex excitability following training was reduced on the MA side for H@Thres, H@50 and H@100 by 96.5 ± 7.7%, 90.9 ± 9.2%, and 62.9 ± 21.1%, respectively. On the less affected side there was a significant decrease in H@Thres and H@50 by 83.4 ± 29.0% and 76.0 ± 28.3%. Time to complete the 10 m Walk Test was not different (5.2 ± 7.9% change, p = 0.06), and time to complete the Timed Up and Go was decreased (9.5 ± 12.3% change, p = 0.05). Spasticity of the ankle plantar flexor muscles, assessed by the Modified Ashworth Scale, was reduced in 4 participants with spasticity. Conclusion: Acute and chronic CPM of the ankle can significantly alter spinal cord excitability. CPM training may be a useful strategy to decrease spasticity of the ankle plantar flexors. / Graduate / 2018-09-15

Názevpráce Komparace efektivity rozcvičení florbalistů Cíle práce Zjistit, které z vybraných druhů rozcvičení má největší vliv na rychlostní výkon florbalisty. Metoda Data pro komparaci efektivity rozcvičení budou dosažena pomocí srovnávací studie, kdy probandi podstoupí různé druhy rozcvičení. Probandi budou testováni testovou baterií, která je součástí kondičních testů české reprezentace. Využity budou fotobuňky zapůjčené od České florbalové unie. Výsledky Zobrazují efektivitu jednotlivých druhů rozcvičení florbalistů. Klíčová slova Rozcvičení, dynamický strečink, florbal, experiment, komparace

The investigations presented in the thesis are theoretical studies of magnetohydrodynamic flows, heat and mass transfer in Newtonian/non-Newtonian cooling liquids, due to horizontal/vertical stretching sheet. The theoretical studies include the effect of magnetic field, uniform and non-uniform heat source/sink (flow and temperature dependent heat source/sink) effects. The considered problems include flow of viscous fluids in the presence of applied magnetic field and electric field with first order chemical reactions. The viscous incompressible Newtonian fluid flow in porous medium with Darcy-Forchheimmer model, electrically conducting fluid and nanofluid is studied. We introduce innovative techniques for finding solutions of highly nonlinear coupled boundary value problems such as Runge-Kutta method, Perturbation method and Differential Transform Method (DTM).   Chapter 1-2 gives a brief introduction. Chapter 3 focuses on Lie group analysis of MHD flow and heat transfer over a stretching sheet. The effects of viscous dissipation, uniform heat source/sink and MHD on heat transfer are addressed. In Chapter 4-6 we examined the laminar flow, thermocapillary flow of a nanoliquid thin film over an unsteady stretching sheet in presence of MHD and thermal Radiation in different situations. An effective medium theory (EMT) based model is used for the thermal conductivity of the nanoliquid.  Metal and metal oxide nanoparticles are considered in carboxymethyl cellulose (CMC) - water base liquid. In Chapter 7-9 we analyzed, heat and mass transfer in MHD, mixed convection, viscoelastic fluid flow, non-Darcian flow due to stretching sheet in presence of viscous dissipation, non-uniform heat source/sink and porous media have been investigated in different situations.  MHD and viscous dissipation have a significant influence on controlling of the dynamics.    In Chapter 10 the linear stability of Maxwell fluid-nanofluid flow in a saturated porous layer is examined theoretically when the walls of the porous layers are subjected to time-periodic temperature modulations. A modified Darcy-Maxwell model is used to describe the fluid motion, and the nanofluid model used includes the effects of the Brownian motion. The thermal conductivity and viscosity are considered to be dependent on the nanoparticle volume fraction. In Chapter 11 we studied MHD flow in a vertical double passage channel taking into account the presence of the first order chemical reactions. The governing equations are solved by using a regular perturbation technique valid for small values of the Brinkman number and a DTM valid for all values of the Brinkman number.