This thesis examines the interaction between the Union Prison System led by William Hoffman and the Confederate prisoners-of-war, specifically those held at Elmira, New York. By focusing on Hoffman's actions and decisions in the last year of the war, the Confederate death toll can be better understood. The treatise relies heavily on The War Of The Rebellion: A Compilation Of The Official Records Of The Union And Confederate Armies. Two studies were indispensable for this study: Hesseltine's Civil War Prisons: A Study In War Psychology, and Leslie's Hunter's Ph.D. Disseration, Warden For The Union: William Hoffman (1807-1884). The conclusions of my research are: (A) William Hoffman developed a change in actions in 1864, and (B) these actions continued in the last year of the war. As a result of his actions and other factors, Elmira had the highest percentage of death of any Union prison camp. Hoffman's actions led to a higher death rate of Confederate prisoners than has been previously recognized.

The purpose of this study was to examine the perceived outcomes of participation in a summer camp that included physical work and service as a major component. A qualitative data analysis approach was used. A convenience sample of 10 male adolescents and 10 parents were selected. The data was analyzed using open, axial, and selective coding. Data analysis was used to ascertain perceived outcomes from the program from both boys and their parents. Analysis of the data showed the emergence of a core theme of boys learning to work and enjoying work. Enjoying work was the term chosen to represent this core theme, and a theory of enjoying work was developed with seven salient attributes. These attributes were that the work was productive and taught skills, provided challenge, was intrinsically rewarding, made a difference for someone else, was done with others, was physical and done outdoors, and took place over an extended period of time.

In 1831, Jackson County, Missouri, was designated as a place of refuge for the members of the Church of Jesus Christ of Latter-day Saints. Attempts to establish permanent residence in their Zion ended in bloodshed and violence. An army was raised to go to the aid of those cast out of their homes. This thesis pays particular attention to the recruiting of the army and the gathering of money and provisions, the trek to Missouri, and the interaction of those promoting and opposing the camp. The trek from Kirtland, Ohio, to Jackson County, Missouri, revealed frustrations, hardships, strengths, weaknesses, and deaths among those who participated in the abortive attempt to redeem the land and reinstate the people. This study also disclosed contrasting reactions of historians to this period of history and the still differing feelings of many who wrote of their personal experience with the camp. The histories of over two hundred men who comprised this trek were studied to determine its impact upon their lives. A strong loyal tie between them and their prophet leader was discovered.

Cyclic nucleotides such as cAMP and cGMP serve as intracellular second messengers in diverse signaling pathways that control a wide range of cellular functions. Such pathways are regulated by key cyclic nucleotide receptor proteins including protein kinase A (PKA), the exchange protein directly activated by cAMP (EPAC), the hyperpolarization-activated cyclic-nucleotide-modulated (HCN) ion channels, and protein kinase G (PKG), and malfunction of these proteins has been linked to a number of pathologies. While it is known that cyclic nucleotide binding to these proteins leads to structural perturbations that promote their activation, the role played by dynamics in auto-inhibition and cyclic-nucleotide-dependent activation is not fully understood. Therefore, in this thesis we examined dynamics within the cyclic-nucleotide receptor proteins EPAC, HCN and PKG, and found that dynamics are critical for allosteric control of activation and/or autoinhibition of all three proteins. In particular, our findings for EPAC and HCN have highlighted dynamics as a key modulator of the entropic and enthalpic components, respectively, of the free-energy landscape for cAMP-dependent allostery, while our findings for PKG have highlighted dynamics as a key determinant of the cGMP-vs.-cAMP selectivity necessary to minimize cross-talk between signaling pathways. Ultimately, we envision that the methods outlined in this thesis will reveal key differences in the regulatory mechanisms of human cyclic nucleotide receptors that can eventually be exploited in the development of novel therapeutics to selectively target a single receptor, and thus treat physiological conditions/diseases linked to malfunction of the target receptor. / Thesis / Doctor of Philosophy (PhD) / In this thesis, we examined cyclic-nucleotide-responsive proteins that regulate key physiological processes, and whose malfunction has been linked to cardiovascular and neurological disorders. In particular, in three such proteins we examined dynamics, whose role in cyclic-nucleotide-responsive function is not fully understood. We found that cyclic-nucleotide-dependent variations in dynamics play a critical role in the function of these proteins, with the results for each protein highlighting a different role played by dynamics. Ultimately, we envision that the methods outlined in this thesis will reveal key functional differences among human cyclic-nucleotide-responsive proteins that can eventually lead to the development of novel therapeutics to treat certain diseases such as arrhythmias or epilepsy by selectively targeting a single cyclic-nucleotide-responsive protein.

No description available.

Diaries are private documentations of people’s lives. They contain descriptions of events, thoughts, fears, and desires. While diaries are usually kept in private, published ones, such as the diary of Anne Frank, show that they bear the potential to give personal insight into events and into the emotional impact on their authors. We present a visualization tool that provides insight into the Bergen-Belsen memorial’s diary corpus, which consists of dozens of diaries written by concentration camp prisoners. We designed a calendar view that documents when authors wrote about concentration camp life. Different modes support quantitative and sentiment analyses, and we provide a solution for historians to create thematic concepts that can be used for searching and filtering for specific diary entries. The usage scenarios illustrate the importance of the tool for researchers and memorial visitors as well as for commemorating the Holocaust.

Livestock grazing is an important part for the livelihood of a large part of the world’s population. While in some areas of the world water accessibility is often taken for granted, in arid regions this can be a limited resource. The central Asian country of Mongolia is one of the countries that sees excessive livestock grazing in an arid region. Nomadic pastoralism is widespread to ensure access to fresh water sources as well as pastures. These movement patterns are under ongoing research, but so far, the impact of water accessibility on these movement patterns has not been investigated. Specifically in the Great Gobi B Strictly Protected Area, pastoralists rely on water obtained from a variety of sources like lakes, rivers, and wells. I analysed camp usage and the availability of water for pastoralists to uncover current movement patterns and how these are influenced by water. I want to gain insight on how the distance to the closest water source influences camp usage and how this changes with seasonality and the size of the herd. For this I conducted Kruskal-Wallis and two-sided Pearson tests respectively. A potential overlap between wildlife and livestock was investigated since this might be a potential conflict and further leading to the spread of diseases. Furthermore, I modelled precipitation and temperature until the year 2050 to spot a potential redistribution of water in an already arid region. There was no correlation found between the seasons nor herd size and the distance to the closest and second closest water source. In my analysis, the overlap between wildlife and livestock was found only to a minor extend. Precipitation and temperature in the region were found to change only to a marginal degree from 2023 to 2050. Due to this, I identified the most important water sources and camps based on the analysisof the current data.

The purpose of this research was to increase understanding of ecology and control of cogongrass (Imperata cylindrica (L.) Beauv.) to assist with management of this invasive grass. To address different aspects of cogongrass management, I examined factors that affect spread of cogongrass, effects of cogongrass on native plant communities, and use of three native species to suppress cogongrass. Relative susceptibility of pine-bluestem and pine-shrub vegetation associations to vegetative encroachment and seed dispersal of cogongrass were evaluated. Vegetative encroachment into burned and unburned areas of these two vegetation associations also was measured. Effects of infestation size on vegetative growth of cogongrass and relationships between military activity and establishment and growth of cogongrass on military firing points were investigated. I also compared frequency of cogongrass infestation and vegetative growth rates for unpaved roads with different levels of traffic and maintenance. Native plant richness, diversity, and abundance were compared between cogongrass infestations and in uninfested adjacent areas for longleaf pine-bluestem and ruderal, cleared areas. Morella cerifera (L.) Small, Chamaecrista fasciculata (Michx.) Greene, and Panicum virgatum L. were tested for their ability to suppress cogongrass re-growth after treatment with a herbicide. Mean vegetative encroachment of cogongrass was < 2 m/yr for both habitat types regardless of burning. Vegetative encroachment was more than double in burned plots compared to unburned plots. Spikelets of cogongrass consistently dispersed farther into pine-bluestem (x¯ =17.3 m) forests compared to pine-shrub forests (x¯ = 9.4 m). Vegetative encroachment was not affected by size of infestation for cogongrass patches on firing points (x¯ < 1 m/yr) (P > 0.643). In areas of soil disturbance from military equipment, vegetative expansion rates of 7-10 m/yr were recorded. There was a positive relationship between military troop use and cogongrass establishment for one of the 2 years of the study (P = 0.023). Growth and establishment of cogongrass did not vary for unpaved roads with differing levels of maintenance and traffic (P > 0.173). Species diversity and abundance of herbaceous vegetation was less in cogongrass infestations compared to uninfested adjacent areas. Complete suppression of cogongrass was not evident for any of three native species tested.

No description available.

No description available.