Made available in DSpace on 2016-03-15T19:40:15Z (GMT). No. of bitstreams: 1 Adriana de Fatima Ribeiro.pdf: 1024780 bytes, checksum: d13e14bac4328d6e7a146f7ac32bb833 (MD5) Previous issue date: 2014-02-13 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Attention Deficit Disorder and Hyperactivity (ADHD) is characterized by a pattern of persistent inattention and/ or hyperactivity that it is more severe than normally observed in individuals with an equivalent level of development. It is a disorder in which the symptoms are varied and may interfere in different degrees according to the environment in which the individual is inserted. The identification of the signs of this disorder must take into consideration an assessment of the neuropsychological functions and of the behavioral indicators, preferably from multiple informants such as parents or guardians, teachers and the adolescent itself. This project aims to identify the main agreements relating to the behaviors of adolescents complaining of symptoms of ADHD observed by multiple informants, and correlate them to their performance on neuropsychological tests. It was used the inventories CBCL/6-18, TRF/6-18 and YSR/11-18 belonging to the Achenbach System of Empirically Based Assessment (ASEBA) and WISC-III, Wisconsin and the Concentrated Attention Test (AC). Twenty adolescents participated in this study aged between 11 and 16 years, divided into two groups, ten with diagnostic (ADHD group) and ten without ADHD (control group). All participants were part of the protocol of neuropsychological, behavioral and clinical assessment to identify signs of inattention and hyperactivity/ impulsivity of the Developmental Disorders Post-Graduation Program at Mackenzie Presbyterian University. The results for the concordance rates in the answers provided by multiple informants in the correlation between CBCL versus TRF, CBCL versus YSR and TRF versus YSR, through values of reference (Q corr), according to the ADM program version 7, were high for both groups. In the comparison of the scales of Internalizing, Externalizing and Total Problems in function of the groups and instruments, as much as for the scales of problems of attention and attention deficit disorder and hyperactivity, it was observed in the ADHD group that the parents reported more problems than the teachers and in the control group the teachers reported significantly greater number of problems. In the comparison of the scales of Sluggish Cognitive Tempo in function of the groups and instruments it was verified that the parents also perceive more alterations in the behavior in different instruments constituents of this scale than the teachers. Regarding to correlations of neuropsychological tests and behavioral indicators of problems of behavior in different instruments, no significant differences were observed. It is therefore concluded the need to compose procedures of assessment of people with the complaint of ADHD with different reporting instruments by multiple informants, besides other procedures such as direct observation or neuropsychological testing for the establishment of a cognitive profile as an aid in the process of assessment. / O Transtorno de Déficit de Atenção/Hiperatividade (TDAH) se caracteriza por um padrão de desatenção e/ou hiperatividade persistente e mais grave do que o normalmente observado em indivíduos com nível equivalente de desenvolvimento. Trata-se de um transtorno cujos sintomas são variados e podem interferir em graus diversos conforme o ambiente no qual o indivíduo está inserido. A identificação dos sinais desse transtorno deve levar em consideração uma avaliação das funções neuropsicológicas e de indicadores comportamentais, preferencialmente a partir de múltiplos informantes como pais ou responsáveis, professores e o próprio adolescente. Este projeto tem como objetivo identificar as principais concordâncias referentes aos comportamentos dos adolescentes com queixa dos sintomas de TDAH, observados pelos múltiplos informantes e posteriormente correlacioná-los ao seu desempenho nos testes neuropsicológicos. Foram usados os inventários CBCL/6-18, TRF/6-18 e YSR/11-18 que pertencem ao Sistema de Avaliação Baseado em Evidência do Achenbach (ASEBA) e WISC-III, Wisconsin e Teste de Atenção Concentrada (AC). Participaram desse estudo 20 adolescentes com idades entre 11 a 16 anos, divididos em dois grupos, 10 com diagnóstico (grupo TDAH) e 10 sem TDAH (grupo controle).Todos os participantes fizeram parte do protocolo de avaliação neuropsicológica, comportamental e clínica para identificar sinais de desatenção e hiperatividade/impulsividade do Programa de Pós-Graduação em Distúrbios do Desenvolvimento, da Universidade Presbiteriana Mackenzie. Os resultados para os índices de concordância nas respostas fornecidas pelos múltiplos informantes na correlação entre CBCL versus TRF, CBCL versus YSR e TRF versus YSR, pelo meio dos valores de referência (Q corr), de acordo com o programa ADM versão 7, mostrou-se alta para os dois grupos. Na comparação das escalas de Problemas Internalizantes, Externalizantes e Totais em função dos grupos e instrumentos tanto quanto para as escalas de Problemas de atenção e Problemas de déficit de atenção e hiperatividade, observou-se no grupo TDAH que os pais relataram mais problemas que os professores e no grupo controle os professores é quem relataram um número significativamente maior de problemas. Na comparação das escalas de Ritmo Cognitivo Lento em função dos grupos e instrumentos, verificou-se que os pais também perceberam mais alterações nos comportamentos constituintes dessa escala que os professores. Com relação às correlações dos testes neuropsicológicos e dos indicadores comportamentais de problemas de comportamento nos diferentes instrumentos, não foram observadas diferenças significativas. Conclui-se, assim, a necessidade de compor procedimentos de avalição de pessoas com queixas de TDAH com diferentes instrumentos de relato por múltiplos informantes, além de outros procedimentos como observação direta ou testagem neuropsicológica para o estabelecimento de um perfil cognitivo para auxiliar no processo de avaliação.

Submitted by Andreza Leão (andrezaflh@gmail.com) on 2018-06-21T17:35:07Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Tese_TDAHBrasilEspanha.pdf: 3304276 bytes, checksum: ce9bf46771071c64d075c0d52a730602 (MD5) / Approved for entry into archive by Celia Santana (celiasantana@ufpa.br) on 2018-12-12T17:49:28Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Tese_TDAHBrasilEspanha.pdf: 3304276 bytes, checksum: ce9bf46771071c64d075c0d52a730602 (MD5) / Made available in DSpace on 2018-12-12T17:49:28Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Tese_TDAHBrasilEspanha.pdf: 3304276 bytes, checksum: ce9bf46771071c64d075c0d52a730602 (MD5) Previous issue date: 2016-11-30 / CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / A presente tese de doutorado objetivou comparar o TDAH no Brasil e na Espanha sob a perspectiva de mães e professores. Essa obra está dividida em 3 estudos: a) O estudo 1, consistiu em uma revisão de literatura dos estudos de prevalência de TDAH nos cinco continentes, enfocando-se as estimativas de prevalência; o processo de amostragem; o tipo de estudo; os critérios diagnósticos; e, as principais variáveis exploradas pelos estudos; b) O estudo 2 comparou a percepção de mães em relação aos problemas de comportamentos listados no CBCL (Child Behavior Checklist) em duas amostras clínicas independentes compostas por pais de crianças brasileiras e espanholas com o diagnóstico de TDAH. O estudo foi do tipo exploratório-descritivo, documental, retrospectivo, transversal, de caráter quantitativo dos prontuários atendidos entre 2010 a abril de 2015 no Hospital Universitário Virgen de la Arrixaca- Murcia/Espanha, e no Hospital Universitário Bettina Ferro de Souza – Belém/Brasil; c) O estudo 3, comparou a perspectiva dos professores no que tange aos problemas de comportamento nos alunos com o diagnóstico de TDAH. Trata-se de uma investigação documental do tipo exploratória-descritiva, retrospectiva e transversal, em que se recorreu a análise de prontuários de crianças e adolescentes, em especial ao TRF (Teacher Report Form) entre os anos de 2013 e 2014 diagnosticados com TDAH em duas unidades clínicas de psicologia situadas no Brasil e Espanha. A principal contribuição desta obra foi encontrar sintomas semelhantes nas duas amostras. A comparação das duas culturas distintas a partir da perspectiva de dois informantes que representam ambientes diferentes, no caso, as mães que avaliaram o comportamento no ambiente familiar, e os professores que interpretaram os sintomas no ambiente escolar, enriqueceram tais achados. / This PhD thesis aimed to investigate ADHD in Brazil and Spain from the perspective of parents and teachers. This work is divided into three studies: a) Study 1 consisted of a literature review of studies on the prevalence of ADHD in five continents, focusing on the estimates of prevalence; the sampling process; the type of study; diagnostic criteria; and the main variables explored by studies; b) Study 2 compared the perception of mothers in relation to behavior problems listed in the CBCL (Child Behavior Checklist) in two independent clinical samples composed of Brazilian and Spanish children with ADHD diagnosis. The study was exploratory-descriptive, documental, retrospective, cross-sectional, quantitative nature of the medical records treated between 2010 to April 2015 at the University Hospital Virgen de la Arrixaca- Murcia / Spain, and the University Hospital Bettina Ferro de Souza - Belém / Brazil; c) Study 3, compared the teacher’s perspective in relation to behaviour problems in students diagnosed with ADHD. This is a documentary investigation of exploratory-descriptive, retrospective and cross-sectional, in which resorted to analysis of children and adolescents records, especially the TRF (Teacher Report Form) between the years 2013 and 2014 diagnosed with ADHD two clinical psychology units located in Brazil and Spain. The main contribution of this work was to find similar symptoms in two independent samples composed of children and adolescents ADHD diagnosis. The comparison of the two different cultures from the perspective of two informants representing different environments, in this case, mothers who evaluated the behavior in the family environment, and teachers who interpreted the symptoms in the school environment, enriched these findings.

Includes vita. / Title from PDF of title page. / Document formatted into pages; contains 137 pages. / Thesis (Ph.D.)--University of South Florida, 2003. / Includes bibliographical references. / Text (Electronic thesis) in PDF format. / ABSTRACT: The researcher examined the relationships between tuberous sclerosis, a multi-system genetic disorder, and school functioning through the use of a parent questionnaire and behavior rating scale. Information was gathered on the typical school experiences of children with tuberous sclerosis, including educational placement and services, behavioral functioning, parent involvement, and parent satisfaction. The results indicated that the majority of students with tuberous sclerosis are in special education and receiving related services. Three-quarters received one or more related services through the public school, and 30% received private related services paid for by their parents. Parent involvement was positively correlated with parent satisfaction, and negatively correlated with t-scores on the Withdrawn/Depressed subscale of the CBCL. / ABSTRACT: Parents of children receiving Autism services were generally less satisfied with their children's school experiences than other parents. Parent satisfaction was negatively correlated with the Attention Problems scale of the CBCL. Student age was negatively correlated with time in inclusion and with related services. This information forms the basis for a discussion of school psychologists' roles in the educational success of students with tuberous sclerosis and the critical areas towards which interventions should be directed. / System requirements: World Wide Web browser and PDF reader. / Mode of access: World Wide Web.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-07-25T23:14:34Z No. of bitstreams: 1 AngelicaLopesCordeiroMandu_DISSERT.pdf: 8297335 bytes, checksum: a571100e33585465a7dd9329c7047ab6 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-08-04T20:58:54Z (GMT) No. of bitstreams: 1 AngelicaLopesCordeiroMandu_DISSERT.pdf: 8297335 bytes, checksum: a571100e33585465a7dd9329c7047ab6 (MD5) / Made available in DSpace on 2016-08-04T20:58:54Z (GMT). No. of bitstreams: 1 AngelicaLopesCordeiroMandu_DISSERT.pdf: 8297335 bytes, checksum: a571100e33585465a7dd9329c7047ab6 (MD5) Previous issue date: 2016-02-18 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Os nevos melanoc?ticos (NMs) s?o prolifera??es benignas de c?lulas n?vicas, que podem serencontradas na pele e em mucosas de revestimento, incluindo a mucosa oral. Contudo, osNMs cut?neos s?o mais comuns, quando comparados os que acometem a mucosa oral. Osmecanismos moleculares envolvidos no desenvolvimento dos nevos e os fatores que podeminfluenciar no padr?o de migra??o das c?lulas n?vicas s?o pouco explorados. O objetivo destapesquisa foi analisar a express?o imuno-histoqu?mica das prote?nas E-caderina e Bcl-2 emNMs orais/cut?neos e relacion?-las com as caracter?sticas cl?nicas (sexo, idade, localiza??o,exposi??o ? radia??o solar) e tipos histopatol?gicos. Foram analisados 36 casos de NMs orais34 de NMs cut?neos. Foi utilizada a t?cnina de imuno-histoqu?mica das prote?nas E-caderinae bcl-2, na qual foram analisados a intensidade (fraca, intermedi?ria e forte) e distribui??o demarca??o (focal e difusa). A imunoexpress?o tamb?m foi analisada quanto aos tipos de c?lulasn?vicas (A, B e C). A an?lise estat?stica foi realizada atrav?s dos testes de Qui-Quadradode Pearson e Correla??o de Spearman com n?vel de signific?ncia estabelecido em 5%. Dos 70casos de NMs, 82,9% eram do sexo feminino, 48,6% com idade entre 26-50 anos, 60% eramda ra?a branca, 51,4% foram diagnosticados histopatologicamente como nevos intrad?rmicos/intramucosos e 80% eram NMs adquiridos. A express?o imuno-histoqu?mica da bcl2 e Ecaderinaforam vari?veis na amostra e n?o exibiram associa??o com os par?metros cl?nicos. Aexpress?o da bcl-2 e E-caderina foram vari?veis de acordo com os tipos de c?lulas n?vicas (A,B e C) (p=0,001). A express?o da bcl-2 foi mais difusa em NMs cong?nitos (p=0,002). A Ecaderinafoi positiva em 83,3% dos NMs <1cm (p=0,001) e em exibiu uma fraca marca??oem 73,9% dos NMs que se encontravam em ?reas expostas (p=0,010). Com base nestes resultados,sugere-se que a E-caderina tenha um controle na determina??o dos tipos histopatol?gicosdos NMs, e que a bcl-2 seja um poss?vel marcador de NMs com maior susceptibilidade aodesenvolvimento de les?es malignas. / Melanocytic nevi (MNs) are benign melanocytic proliferations of cells, which can be found in the skin and mucous coat, including the oral mucosa. However, skin NMs are more common when compared to those that affect the oral mucosa. The molecular mechanisms involved in the development of nevi and the factors that can influence the migration pattern of the nevus cells are little explored. The aim of this study was to analyze the immunohistochemical expression of E-cadherin protein and Bcl-2 in oral / skin NMs and relate them to the clinical characteristics (gender, age, location, exposure to solar radiation) and histopathological types. 36 cases of oral NMs and 34 Skin NMs were analyzed. The immunohistochemistry was used of the protein E-cadherin and bcl-2, which were analyzed the intensity (weak, moderate and strong) and distribution marking (diffuse and focal). The immunoreactivity also analyzed as to the types of nevus cells (epithelioid cells -A, -B lymphocyte and fibroblast-like -C). Statistical analysis was performed using the chi-square tests of Pearson and Spearman correlation with significance level set at 5%. Of the 70 cases of NMs, 82.9% were female, 48.6% aged 26-50 years, 51.4% were diagnosed histologically as intradermal / intramucosal nevi and 80% were NMs acquired. Immunohistochemical expression of BCL2 and E-cadherin were variables in the sample and showed no association with clinical parameters. The expression of bcl-2 and E-cadherin were variable according to the types of nevus cells (A, B and C) (P = 0.001). The expression of bcl-2 was more diffuse in congenital MNs (p = 0.002). E-cadherin was positive in 83.3% of MNs <1cm (p = 0.001) and exhibited weak staining in 73.9% of MNs that were in exposed areas (p = 0.010). Based on these results, it is suggested that the E-cadherin has a modulating effect on the migratory properties of NMs, and bcl-2 is a marker of MNs with increased proliferative capacity.

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La presente ricerca nasce da una domanda di un territorio specifico che si è interrogato relativamente ai problemi emotivo-comportamentali dei bambini in età prescolare Tale richiesta ci ha sollecitato da un punto di vista teorico a porre l’attenzione da un lato, sul significato “clinico” dei problemi emotivo-comportamentali dei bambini, dall’altro sul processo di assessment e in particolar modo sulla prospettiva multi-informant . Tale prospettiva è stata nello specifico oggetto di riflessione e indagine empirica soprattutto nel primo studio dove si sono considerate con particolare attenzione le discrepanze tra gli informant e il loro possibile significato. La domanda di ricerca iniziale si è quindi ampliata fino ad affrontare l’individuazione dei fattori protettivi e di rischio nello sviluppo psicologico dei bambini in età prescolare. A questo proposito il secondo studio propone un modello multifattoriale per la comprensione delle problematiche emotivo-comportamentali dei bambini che tiene conto di aspetti individuali e di aspetti relazionali, familiari in primo luogo. Infine, il terzo studio vede l’utilizzo del modello teorico proposto nei i primi due studi su di un campione di genitori che si sono rivolti a un servizio territoriale arrivando a identificare gli elementi del modello che discriminano famiglie considerate normali da quelle definibili come cliniche. / This research developed from a need to answer specific questions about emotional-behavioral problems in preschool children. From a theoretical point of view, this need forced one to focus on the “clinical” meaning of emotional-behavioral problems in pre-school children and their assessment processes, especially from a multi-informant perspective. Particularly, this perspective was a topic of interest in an empirical investigation in the first study, where discrepancies between informants and their possible perceptions were considered with particular attention. The initial research question was expanded to deal with the identification of risk and protective factors in the psychological development of preschool children. On this regard, the second study proposed a multi-factorial model to understand the emotional and behavioral problems of children which took into account individual and relational aspects, including especially the family. Finally, the third study considered the use of a theoretical model proposed in the first two studies with a sample of parents who turned for help to social services to identify from the model critical elements that discriminated families which could be considered functional from those defined as clinical.

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