Dans ce travail de thèse, certaines étendues d’eaux continentales regroupant plusieurs types de système de dépôt comme les lacs, mers intérieures et lagunes ont été regroupées au sein d'un nouveau groupe de système sédimentaire mentionnés sous l'appellation de Wind-driven Water Body (WWB).Afin de caractériser l'évolution et l'enregistrement sédimentaire d'un exemple de WWB, une étude sédimentologique intégrée du bassin quaternaire du Lac Saint-Jean (Québec, Canada) a été menée à partir d'une approche intégrant géologie de terrain et imagerie géophysique très haute résolution (CHIRP 2D). A l'échelle du cortège sédimentaire, le régime glaciaire à paraglaciaire de la sédimentation et le rebond glacio-isostatique ont contrôlé au premier ordre, à la fois la succession lithologique et les architectures grandes échelles du bassin pour générer un Cortège de Régression Forcée (CRF) atypique. Au sein de ce cortège de régression forcée fini-glaciaire, une dynamique de système WWB s'est progressivement affirmée à partir de 8,5 cal. ka BP. Elle s'est exprimée par la mise en place d'une dynamique littorale importante occasionnellement associée à une circulation interne générant des courants de fonds lors d'épisodes de vents forts.Finalement, l'analyse sédimentologique du bassin du Lac Saint-Jean a permis de dégager plusieurs interprétations ayant attrait (1) à l'évolution des systèmes WWB et (2) aux séquences de déglaciation en domaine précédemment englacé. De plus, ce travail représente une contribution à l'échelle régionale pour les modalités de la dernière déglaciation du Sud-Est du Québec. / In this study, a certain number of continental enclosed basins including several depositional systems such as lakes, inland seas or lagoons have been grouped in a new sort of sedimentary system referred to as Wind driven Water Body. To characterize the sedimentary evolution and record of a WWB basin, an integrated sedimentological study has been carried out on the quaternary Saint-Jean basin (Québec, Canada) based on field onshore geology and offshore geophysics (CHIRP 2D).At the system-tract scale, the glacial to paraglacial sedimentation and the glacio-isostatic rebound controlled at first-order the lithofacies succession and large-scale architectures to generate an original Falling Stage System Tract (FSST). Within this FSST, since 8.5 cal. ka BP a WWB related sedimentary evolution overprinted the glacial to paraglacial evolution. This expressed in the form of the emplacement of an important coastal dynamics, occasionally accompanied by a lake-scale hydrodynamics at the origins of bottom currents during strong wind to storm events.Finally, the sedimentological analysis of the Saint-Jean basin brought numerous interpretations related to (1) the sedimentary evolution of WWB systems and (2) deglaciation sequences in previously glaciated domains. In addition, this work supplements the regional quaternary framework concerning the latest deglaciation evolution in southeast Quebec.

Analisamos aproximadamente três anos de dados correntográficos, em toda a coluna d\'água, e de temperatura junto ao fundo, a fim de avaliar o comportamento hidrodinâmico e termal nas proximidades da Quebra da Plataforma Continental (QPC) de Cabo Frio (CF, Rio de Janeiro, Brasil - 23° 20\'S). A Corrente do Brasil (CB) força movimentos apontando para sudoeste, paralelos à isóbata, em todos os níveis verticais, com variação sazonal das intensidades: médias máximas para o verão (58,7 cm/s) e primavera (41,4 cm/s) e mínimas para inverno (31,0 cm/s) e outono (22,8 cm/s). Foram obtidos máximos significativos de correlação entre as correntes paralelas à isóbata, em toda a coluna d\'água, e o vento na mesma direção, com defasagem na resposta das correntes da ordem do período inercial local (31 h). Também foram obtidos máximos significativos de correlação entre as correntes de fundo normais à isóbata, e a componente paralela do vento, concordantes com mecanismos de intrusões de Água Central do Atlântico Sul (ACAS) na plataforma continental, as quais antecedem a conhecida ressurgência costeira de CF. Sazonalmente, os resultados concordaram principalmente com as variações de posicionamento da frente da CB na QPC e, secundariamente, com a variabilidade dos ventos. Os dados de temperatura indicaram presença quase permanente da ACAS no fundo, e os máximos de correlação obtidos com as correntes paralelas à isóbata indicam que águas mais quentes, oriundas do núcleo da CB (Água Tropical), se aproximam do fundo da QPC, principalmente durante o verão. As correntes de maré se mostraram fracas em todo o período avaliado, com importância decrescendo da superfície para o fundo (20 e 10% da variância, respectivamente) / Current data throughout the water column and temperatures at the bottom from about three years have been analyzed in order to evaluate the hydrodynamic and thermal behavior near the Cabo Frio (CF) continental shelf break (23° 20\'S - Rio de Janeiro, Brazil). The Brazil Current (BC) forces movements pointing to SW, isobath-aligned, on all vertical levels. The speed varies seasonally, with surface mean currents maximum on summer (58.7 cm/s) and spring (41.4 cm/s), and minimum on winter (31.0 cm/s) and autumn (22.8 cm/s). Significant maximum correlation was found between subinertial winds and driven-wind currents, both isobath-aligned, with a delay next to the local inertial period (31 hours). Significant maximum correlation were also obtained between bottom cross-isobath currents and the isobath-aligned component of the wind, consistent with the South Atlantic Central Water (SACW) transport towards the continental shelf, which antedates the well-known coastal CF upwelling. Seasonally, the results agreed mainly with the positioning variations of the BC to the shelf break and, secondly, with the local winds variability. The temperature values below the 18ºC (SACW thermohaline index) was almost permanent on the bottom of the shelf break, and the maximum correlation obtained with current along the isobath indicates that the warmer water of the BC nucleus (Tropical Water) approaches to the bottom of the shelf break, especially during the summer. Tidal currents were weak during the entire sampling period, decreasing the relative strength from the surface to the bottom (20% and 10% of the variance, respectively)

Clinical evidence suggested patients with lower plasma C-reactive protein (CRP) levels after statin therapy could have better clinical outcome. The last part of the study was to measure on-treatment high sensitivity CRP (hsCRP) levels among 229 Chinese patients with hyperlipidaemia undergoing treatment with simvastatin 40 mg daily. The patients were genotyped for 15 SNPs or haplotypes in 11 candidate genes that would have significant allele frequency among Chinese patients and may be linked to statin efficacy or hsCRP levels. The analysis suggested BMI is the largest single contributing factor of 15.0% of the variation in hsCRP levels, followed by plasma triglycerides levels contributing 4.7% and male gender 1.6% (all P<0.05). However comparisons of hsCRP levels among genotype groups did not reveal any significant findings, with or without adjustment with covariate genotypic or phenotypic factors. To further categorize individuals as high or medium risk, we set a threshold hsCRP level of 1 mg/L as the benchmark for evaluation. The CRPc.3872G>A SNP was related to lower risk compared to the homozygous wild-type genotype (adjusted odds ratio AOR = 0.289; P = 0.014) after adjusting for phenotypic factors of age, gender, smoking status, BMI, waist circumference, hip circumference, plasma lipid profiles, co-existing disease and co-medications. Another marginal finding included the HNF1A c.79A>C SNP (AOR = 0.575; P = 0.118). / Polymorphisms in the drug transporters are likely to be more important with hydrophilic statins such as pitavastatin, which undergoes transporter mediated distribution. The SLCO1B1 c.388A>G polymorphism in the gene encoding the uptake transporter organic anion transporting polypeptide (OATP1B1) is common in Chinese and the variant was associated with increases of 63--68% in maximum plasma concentration and 44--47% in systemic exposure of both the lactone and acid compared to wild-type subjects (P<0.05). Co-administration of pitavastatin with grapefruit juice (GFJ) resulted in a small increase of the area under the plasma concentration time curve (AVC) by 15--16% for both the acid and lactone (P<0.05). However, there was no significant effect on the drug-food interaction in relation to relevant SNPs in the enzymes and transporters examined. / The SNPs examined included those in the genes for the enzymes and transporters involved in the metabolic pathway or the distribution of simvastatin. Cytochrome P450 (CYP) enzymes are involved in hepatic and intestinal metabolism of several statins and simvastatin is known to undergo extensive metabolism via the CYP3A4/3A5 pathway. The common candidate SNPs in the CYP3A4/3A5 enzymes found in Chinese populations include CYP3A4*1G, CYP3AP1*3 and CYP3A5*3 , which are associated with altered enzyme expression and activity. However, no statistically significant relationship was found between these SNPs and a potential phenotypic marker of enzyme activity, the urinary ratio of 6beta-hydroxy-cortisol/cortisol (6beta-OHC/C) concentrations. The analysis of lipid lowering responses in relation to individual SNPs or combinations from gene-gene interactions also revealed no statistically significant findings. In the subgroup of patients with familial hypercholesterolaemia, the CYP3A4*1G, CYP3AP1*3 and CYP3A5*3 polymorphisms appeared to have a small effect on the changes in LDL-C and total cholesterol with the subjects with the CYP3A5*3 and CYP3AP1*3 variants showing less reduction and those with the CYP3A4*1G variant showing more reduction than subjects with the wild-type genotype with a tendency for a gene-dose effect. It is difficult to interpret these findings and the significance may be related to multiple testing. / The statins, or 3-hydroxymethyl-3-glutaryl coenzyme A (HMG-CoA) reductase inhibitors, act on the rate limiting step in endogenous cholesterol synthesis. Their primary action results in reduction of plasma low-density lipoprotein cholesterol (LDL-C) levels and this is thought to be the major mechanism by which they reduce cardiovascular events. There are considerable differences between subjects in both the plasma levels of the statins and in their effects on LDL-C and other lipid parameters and some of this variation appears to be related to genetic differences in the pathways of drug metabolism and distribution and in the pathways involved in lipid metabolism. / The variation in response may be related to variations in systemic or hepatic exposure to the drug, which in turn will be related to the pharmacokinetics. This is also likely to play a role in the adverse effects of myopathy and therapeutic tolerance. In a pharmacokinetic study in healthy male Chinese subjects, the common polymorphism of CYP2D6*10 was analyzed in relation to the pharmacokinetics of lovastatin and simvastatin. There was a tendency for reduced clearance of simvastatin lactone by 30% (P>0.05) in subjects with the CYP2D6*10/*10 genotype. With lovastatin, there were similar findings with 38.5--84.9% decrease in clearance which appeared to be related to enzyme activity according to genotype, with *5 carriers showing a greater decline in clearance than *10 carriers (P<0.05). / These results provide some insights into the pharmacokinetics and pharmacodynamics of statins and the pharamacogenetic relationships to candidate SNPs. Future research in this field should help to facilitate safer and more effective treatment with these commonly used medications, resulting in personalized therapy and optimal clinical benefits for patients with cardiovascular disease. / This thesis describes a study of 270 patients recruited from the outpatient clinics at the Prince of Wales Hospital who were treated with simvastatin 40 mg daily for at least 4 weeks. Their mean (+/-SD) LDL-C baseline level was 5.38+/-1.68 mmol/L and the reduction in LDL-C after simvastatin treatment was 2.81+/-0.99 mmol/L or -47.1+/-12.5%. / Mak, Wah Lun Valiant. / Adviser: Brian Tomlinson. / Source: Dissertation Abstracts International, Volume: 73-06, Section: B, page: . / Thesis (Ph.D.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 253-289). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

A mixed-methods design consisting of two phases was adopted. In Phase I, a purposive sample of 31 older Clnnese people with KOA was invited for a semi-structured interview to explore their perceptions and experiences of exercise. Five major categories emerged: typical living pattern with KOA, self-management of KOA, the practice of exercise, views about exercise, and preferences for learning exercise. The findings were used in the development of an exercise programme for this client group. / Knee osteoarthritis (KOA) is prevalent in the growing older Chinese population in Hong Kong. Therapeutic exercise for KOA has strong empirical evidence of its effectiveness on reducing knee pain and physical disability in people with KOA provided that they persists in practising the recommended exercise regimen. However, few previous studies have incorporated the client's perspectives into the design of an exercise programme for promoting continual practice of exercise. This study aimed to develop a new therapeutic exercise programme and pilot its acceptability to promote continual practice for older Chinese people with KOA. / The Phase II study used both quantitative and qualitative approaches to examine participants' satisfaction with the new exercise programme, adherence to the prescribed exercises, mastering of the exercise movements and health outcomes (knee pain, stiffness and range-of-motion, physical function, muscle strength and endurance of the lower extremities, and quality of life). A convenience sample of 33 older Chinese people with KOA participated in the programme. Seven measurement tools in Chinese versions (if applicable) were used to collect quantitative data from the participants: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the 12-item Short Form of the Medical Outcome Study Questionnaire (SF-12), a goniometer, the Timed-Stands Test (TST), a satisfaction questionnaire, an exercise diary, and a return-demonstration performance record sheet. Six of the participants were invited for a semi-structured interview to explore their experience of the programme. / The quantitative results showed that the participants were highly satisfied with the exercise programme with a mean score of 90.15 out of 100 (SD = 8.05). Their average exercise adherence was high with a mean percentage of 91.04% (SD = 14.54) and their overall performance in mastering of the exercise movements was good with a mean score of 76.71 out of 100 (SD = 21.75). Most participants' health outcomes significantly improved at three months after the exercise programme, except for the SF-12 physical health summary score. The qualitative findings revealed four major categories: satisfaction with the exercise programme, mastering of the exercise movements, experience of the exercise's effects, and integration of the exercises into the daily routine. These findings were mainly consistent with the quantitative results of the study. / The results of this study showed that the exercise programme was acceptable to the participants in terms of satisfaction with the programme, adherence to the prescribed exercises and mastering of the exercise movements. Therefore, adopting a client-centred approach is likely to be a way forward in the development of exercise programmes for promoting continual practice of therapeutic exercise regimens by older Chinese people with KOA. / Lee, Fung Kam. / Advisers: Tak Ying Ann Shiu; Tze Fan Diana Lee; Kwok Wei Winnie So. / Source: Dissertation Abstracts International, Volume: 73-06, Section: B, page: . / Thesis (Ph.D.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 332-369). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese; some appendixes in Chinese.

Made available in DSpace on 2016-04-25T20:22:34Z (GMT). No. of bitstreams: 1 Marcia Regina Silva do Vale.pdf: 7437402 bytes, checksum: 179adcd19266758ad92f61d36f6e470a (MD5) Previous issue date: 2008-12-05 / The study focuses on the issue of concentration of population in the continental area of the São Vicente city. First city in Brazil, São Vicente keeps contradictions that are stressed from the 1970 with the settlement of its continental area. In this period began to emerge to communities formed mainly by migrants from the north and northeast of the country. To pursue its inclusion as São Vicente citizens, this kind of group from the São Vicente will consider the school of basic education as a source of improved living standards. In this first decade of the new century, the school of basic education is therefore high on the communities of the continental area of São Vicente, it works as unifying the population resident in the place. The intensification of this phenomenon directed the council for the region to revert to the lack of education by increasing the number of schools and places for children. The social movement of the population from the continental area ends winner because articulates Vicente citizens of the island area and the power of the council in public benefit them when fighting for their beliefs / O estudo enfoca a questão da concentração populacional na área continental da cidade de São Vicente. Primeira cidade do Brasil, São Vicente guarda contradições que se acentuaram a partir da década de 1970 com o povoamento de sua área continental. Nesse período começaram a surgir às comunidades formadas principalmente por migrantes do norte e nordeste do país. Ao visarem sua inserção como cidadãos vicentinos, esse contingente populacional passa a considerar a escola de ensino fundamental como fonte de melhoria das condições de vida. Nessa primeira década do novo século, a escola de ensino fundamental ocupa lugar de destaque para as comunidades da área continental de São Vicente, pois funciona como aglutinadora da população residente no local. A intensificação desse fenômeno direcionou o município para a região no sentido de reverter à falta de escolarização aumentando o número de escolas e vagas para as crianças. Esse movimento social da população ma área continental termina vencedor porque articula os cidadãos vicentinos da ilha e o poder público do município em beneficiá-los quando lutam por suas convicções

Nos estudos de populações pesqueiras é comum o uso de modelos hidrodinâmicos acoplados a modelos biológicos e, um tipo de modelo merece destaque: o baseado no indivíduo (IBM). A Plataforma Continental do Atlântico Sudoeste comporta uma importante atividade pesqueira e, a influência da circulação na distribuição de ovos/larvas nessa região é pouco entendida. Estudos anteriores sugerem que o transporte de Ekman em direção à costa e o deságue de água fluvial impedem a perda de ovos e larvas da área costeira. Este trabalho apresenta resultados de um estudo englobando os padrões de circulação e de transporte de larvas nessa área, realizado através do desenvolvimento de um IBM para os estágios iniciais da Engraulis anchoita e o acoplamento deste a dois campos de velocidade superficial: a de Ekman, e a saída de um modelo hidrodinâmico 3D. Os resultados mostram que somente a deriva de Ekman não é suficiente para explicar o padrão de retenção larval observado na região. Os valores de retenção encontrados com a utilização da saída do modelo estão próximos aos observados. Maiores concentrações larvais foram obtidas no outono/inverno e menores na primavera/verão. Estes resultados estão diretamente relacionados à combinação dos efeitos dos padrões de vento da área com a influência das Correntes do Brasil e das Malvinas e do deságue continental na circulação sobre a plataforma. / Recruitment of pelagic fishes is the net result a series of continuous events in their life cycle. Most of the variability in natural mortality is thought to occur during the early stages of development and is related to environmental factors. The use of coupled physical-biological modeling in the study of fisheries populations is very common and a particular type of model deserves special mention: the Individual Based Model (IBM). The Atlantic Southwestern Continental Shelf is one of the most productive fishing sites in the Western South Atlantic, but the processes involving the circulation in this area and its influence on eggs/larvae transport and retention are still poorly understood. Recent studies describe the spawning activity of anchovy and its relationship to oceanographic processes and suggest that predominant onshore Ekman transport, during the austral winter/spring, keeps the eggs and larvae in coastal areas. According to these studies, the river runoff contributes to the formation of a retention zone for planktonic organisms over the area. This work presents results of a study that considers both the circulation pattern and larval transport, throught the development of an IBM for the early stages of anchovy Engraulis anchoita. The model is coupled to two surface velocity fields: the Ekman drift, and the output of a 3D hydrographic model. The results show that just Ekman surface velocities are not able to explain the larval dispersion observed in this region. Retention values obtained with the model output are much closer to observed values. Autumn and winter seasons present the highest values of retention. These results are due to the combined effect of the wind patterns registered in the area with the influence of the river runoff and the Brazil-Malvinas shelf circulation.

A dinâmica da matéria orgânica particulada (MOP) nos oceanos, desde sua formação até seu consumo/exportação, é um elo importante no ciclo biogeoquímico do carbono e elementos associados, que ganhou importância nas últimas décadas devido ao aumento do CO2 antropogênico. Para melhorar os modelos e as previsões climáticas, projetos oceanográficos investigam os fatores que influenciam na dinâmica da MOP, sobretudo em regiões produtivas e representativas em escala global. No Atlântico Sul, a região mais produtiva é ao largo do continente africano, devido à contínua ressurgência de borda leste. Entretanto, regiões hidrograficamente dinâmicas também podem contribuir com elevadas taxas de produção dependendo das condições ambientais, cuja importância no reservatório de MOP ainda é desconhecida. Este trabalho tem como objetivo estudar a dinâmica do MOP em suspensão em duas regiões também produtivas do Atlântico Sudoeste: (i) o setor externo da Margem Continental Sudeste Brasileira (Capítulo 1); e (ii) o setor Austral ao sul de 30ºS (Capítulo 2). São discutidos os efeitos das condições oceanográficas no reservatório de MOP e seus padrões interanuais de distribuição geográfica. / The dynamics of particulate organic matter (POM) in the oceans, from its formation to its consumption/export, is an important link in the biogeochemical cycle of carbon and associated elements, which gained importance in the last decades due to increase of anthropogenic CO2. To improve models and climate predictions, oceanographic projects investigate the factors that influence the POM dynamics, especially in productive and representative regions on a global scale. In the South Atlantic, the most productive region is off the African continent, due to permanent Eastern Boundary upwelling. However, dynamic hydrographic regions can also provide with high production rates depending on environmental conditions, whose importance in the POM reservoir is still unknown. This work aims to study the suspended POM dynamics in two productive regions of the southwest Atlantic: (i) the outer Brazilian Southeast Continental Margin (Chapter 1); and (ii) the Austral sector south of 30ºS(Chapter 2). The effects of different oceanographic conditions in the POM reservoir, their interannual pattern and geographic distribution are discussed.

Made available in DSpace on 2016-04-26T14:57:25Z (GMT). No. of bitstreams: 1 Marcia Regina Silva do Vale.pdf: 7437402 bytes, checksum: 179adcd19266758ad92f61d36f6e470a (MD5) Previous issue date: 2008-12-05 / The study focuses on the issue of concentration of population in the continental area of the São Vicente city. First city in Brazil, São Vicente keeps contradictions that are stressed from the 1970 with the settlement of its continental area. In this period began to emerge to communities formed mainly by migrants from the north and northeast of the country. To pursue its inclusion as São Vicente citizens, this kind of group from the São Vicente will consider the school of basic education as a source of improved living standards. In this first decade of the new century, the school of basic education is therefore high on the communities of the continental area of São Vicente, it works as unifying the population resident in the place. The intensification of this phenomenon directed the council for the region to revert to the lack of education by increasing the number of schools and places for children. The social movement of the population from the continental area ends winner because articulates Vicente citizens of the island area and the power of the council in public benefit them when fighting for their beliefs / O estudo enfoca a questão da concentração populacional na área continental da cidade de São Vicente. Primeira cidade do Brasil, São Vicente guarda contradições que se acentuaram a partir da década de 1970 com o povoamento de sua área continental. Nesse período começaram a surgir às comunidades formadas principalmente por migrantes do norte e nordeste do país. Ao visarem sua inserção como cidadãos vicentinos, esse contingente populacional passa a considerar a escola de ensino fundamental como fonte de melhoria das condições de vida. Nessa primeira década do novo século, a escola de ensino fundamental ocupa lugar de destaque para as comunidades da área continental de São Vicente, pois funciona como aglutinadora da população residente no local. A intensificação desse fenômeno direcionou o município para a região no sentido de reverter à falta de escolarização aumentando o número de escolas e vagas para as crianças. Esse movimento social da população ma área continental termina vencedor porque articula os cidadãos vicentinos da ilha e o poder público do município em beneficiá-los quando lutam por suas convicções

2)Qualitative study: Three areas were discussed: i) Generational differences in dietary practices were apparent and it was attributable to the discrepancies in the food environment during childhood, attitudes towards family meals, and practices of regular meal schedules between generations; ii) Mothers were influential but did not recognize their influences on their adult daughters' diet. Ignorance of the importance of diet-health relationship in young adulthood was observed; iii) Effects of media food promotions were apparent in the presence of Westernized food environment and reduced family size. Health and diet information in the media induced both positive and negative effects on the dietary behaviours of Chinese women. / Background: Studies on the characteristics associated with the Western dietary pattern (DP) in Asia are limited. Understanding the family DP resemblance in Asia is of public health importance because of the possible beneficial effects of intergenerational transfer of traditional plant-based Asian diet. Studies about media influence on dietary behaviours in Asia are few and none studied the effects on the overall DP. / Conclusion: There is an intergenerational association for practicing Western DP within family. Mothers were influential in adult daughters' dietary intakes, through modelling and family meals. A dose-response relationship exists between the practice of Western DP and media exposure in Chinese women. Public health strategies should consider promotion of family meals and empowerment of women on quick and healthy cooking skills as long-term approaches for family health promotion and obesity prevention. Policy evaluation of food or food-related advertising standards is necessary. / Keywords: mother, daughter, dietary pattern, media exposure, family meal, Western, TV viewing / Methods: This thesis composes two studies as follows: 1)a cross-sectional study on Western DP and media exposure; 2)a qualitative study on media influences on dietary practices. / Objective: This study aims to examine the dietary and individual characteristics associated with Western DP, investigate the association between the practice of Western DP and media exposure, and qualitatively assess how media and other factors influence the dietary practices in two generations of Chinese women. / Results: 1)Cross-sectional study: Western DP was characterised by higher intakes of meat (red, processed, poultry), fast foods, seafood, energy-dense foods (e.g. high-fat dairy, cakes and snacks), eggs, energy, fat, and dietary cholesterol. Daughters had a higher Western DP score than their mother. Western DP score was positively associated with the time spent on total media exposure and years living in Hong Kong for mothers, and with the time spent on TV viewing, mother's Western DP score, and smoking status for daughters. Western DP score was positively associated with the prevalence odds of being overweight and negatively associated with the frequency of family meals for both mothers and daughters. / The cross-sectional study recruited 207 (103 mothers, 104 daughters) community-based women from a longitudinal study. Dietary intake was quantified by an interviewer-administered diet history questionnaire. A self-reported questionnaire assessed the media (newspapers, magazines, radio, television, and leisure-time internet use) and other exposures (demographics, leisure-time physical activities, and lifestyles). Anthropometric data are measured. Two major DPs (Western and prudent) were identified using principal component analysis. Generation-specific factors associated with DPs were identified by multiple linear regression analyses adjusted for age and energy intake. / The qualitative study enrolled 22 mothers and 13 daughters from the same study population for semi-structured in-depth interviews. Themes were identified corresponding to the environmental levels described by the Ecological Model, with quotations supported. The final themes were evaluated by participant validation. / Lee, Suk Yin Roselle. / Adviser: Suzanne C Ho. / Source: Dissertation Abstracts International, Volume: 73-02, Section: B, page: . / Thesis (Ph.D.)--Chinese University of Hong Kong, 2010. / Includes bibliographical references (leaves 222-250). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [201-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

Este trabalho tem como objetivo a identificação de feições que permitam (1) a construção do arcabouço crustal profundo e da porção superior do manto em parte da Costa de Angola, (2) a comparação deste arcabouço com o embasamento aflorante e (3) a tentativa de adequar estes resultados aos modelos de ruptura continental já publicados. Para alcançar estes objetivos foi feita a interpretação de cinco linhas sísmicas de reflexão profundas (25 Km de profundidade) na costa de Angola, nas Bacias de Kwanza e Baixo Congo, adquiridas pela ION-GXT. As feições identificadas na sísmica de reflexão auxiliaram na determinação dos limites da crosta continental superior e inferior, no reconhecimento das camadas que compõem a crosta oceânica e na identificação da Descontinuidade de Mohorovicic (que marca o limite entre crosta e manto). A interpretação sísmica associada a dados da literatura (que proporcionaram valores de densidade para os pacotes identificados na interpretação sísmica) permitiram a realização de uma modelagem gravimétrica que foi comparada ao dado gravimétrico adquirido durante a aquisição sísmica. A modelagem gravimétrica serviu para validar a interpretação sísmica, atuando como um controle de qualidade para a interpretação. Caso a anomalia gravimétrica gerada pela modelagem não estivesse de acordo com a anomalia medida, a interpretação sísmica era revista na tentativa de um melhor ajuste entre o resultado modelado e o medido. Este ajuste, no entanto, sempre foi feito honrando os refletores que estavam bem marcados na sísmica. Somado a isto, ainda foi utilizado o dado magnético adquirido no campo, no auxilio da interpretação. O arcabouço crustal obtido com a utilização deste método permitiu a comparação dos resultados da interpretação com os modelos de evolução de margens passivas existentes na literatura, mostrando muitos pontos em comum aos modelos que defendem a possibilidade de ocorrência de manto exumado em margens passivas pobres em magmatismo. A interpretação final destes dados mostrou um domínio proximal marcado por uma crosta continental espessa porém pouco afinada em contato com um domínio distal marcado por uma crosta continental muito afinada (crosta hiper-estirada) e, em direção ao centro do oceano, uma região em que ocorre a exumação do manto. A passagem do domínio proximal para o distal ocorre de forma rápida em uma região denominada Zona de Estrangulamento. À oeste do manto exumado é possível identificar a crosta oceânica. O cruzamento dos resultados obtidos neste trabalho com dados do embasamento aflorante no continente africano sugerem um controle do deste nos valores finais de afinamento da crosta continental sob a bacia e nas regiões de manto exumado. Trabalhos recentes realizados na costa de Angola e do Brasil mostram feições semelhantes às identificadas nesta dissertação. / The main objectives of this study are to identify features on seismic data that allow (1) the building of a deep crustal framework and of the upper portion of the mantle, in part of the Angolan margin; (2) to compare this framework with the adjacent outcropping basement of the African continent and; (3) to try to fit these results to the published continental breakup models. In order to achieve these objectives, five deep reflection seismic lines (25 km of depth) situated in the in Kwanza and Lower Congo Basins on the passive margin of Angola were interpreted. The features identified on seismic were useful to recognize the tripartite division that caracterize the oceanic crust and in defining the Mohorovicic Discontinuity (that represents the limit between crust and mantle). The seismic interpretation associated with the data obtained from the scientific literature (that provided density values for the packages identified on seismic interpretation) allowed the establishment of a gravity modeling that was compared to the gravity data acquired during the seismic acquisition. The gravity model was useful to validate the seismic interpretation, acting as a quality control of the latter. In case of the gravity anomaly generated by the modeling not being in accordance with the measured anomaly, the seismic interpretation was revised in order to obtain a better adjustment between the modeled and the measured result. This adjustment, however, was always done honoring the reflectors that were clearly positioned on seismic. In addition, the magnetic data acquired on the field was used to help on interpretation. The crustal framework obtained by the methodology described above was compared with the passive margin evolution models found on scientific literature, showing some points in common with the models that postulate the occurrence of exhumed mantle in magma-poor passive margins. The final interpretation of these data showed the existence of a proximal domain characterized by a thick continental crust slightly thinned in contact with a distal domain marked by a hyper-extended continental crust. Oceanwards there is a region where the exhumation of the mantle took place. The passage of the proximal to the distal domain is abrupt, here termed as a Necking Zone. Oceanic crust is identified to the west of exhumed mantle. The comparison of the results obtained in this study with data from the outcropping basement on the African continent suggests a basement control on the vales of continental crust thinning attained under the basins and on the regions of exhumed mantle. Recent works done on the Angolan and Brazilian margins show features similar to the ones identified on this dissertation.