The topic of my diploma thesis is the issue of nursing care in pediatric pati- ents before consumption of organs at the resuscitation department. I consider this topic socially very topical because the number of transplant candidates on transplantation lists is constantly increasing. Since child transplant can- didates are the most vulnerable group, I have focused on child organ donors. The theoretical part criticizes the concept of death and threat, including examination methods that lead to brain death. I present the activities of the Coordination Center of the Transplant and Coordinated Coordinator in a donor program that seeks to proliferate the transplant program. An important component is legal legislation and ethical aspects, which are an integral part of the donor system in the Czech Republic. Study materials I searched in the databases NLK, SVKKL, Medvik, Embase, PubMed, Wiley Online Library, Medscape. The research was conducted from the National Medical Library and from the Central Bohemian Library in Kladno. I got statistical data from web sources, especially from KST. Methodology: The choice of the case study best fulfills the requirements necessary to map the key moments of nursing care, which may play a role in the timely indication of a potential organ donor, as well as in considering...

The topic of my diploma thesis is the issue of nursing care in pediatric patients before consumption of organs at the resuscitation department. I consider this topic socially very topical because the number of transplant candidates on transplantation lists is constantly increasing. Since child transplant candidates are the most vulnerable group, I have focused on child organ donors. The theoretical part criticizes the concept of death and threat, including examination methods that lead to brain death. I present the activities of the Coordination Center of the Transplant and Coordi- nated Coordinator in a donor program that seeks to proliferate the transplant program. An important component is legal legislation and ethical aspects, which are an integral part of the donor system in the Czech Republic. Study materials I searched in the databases NLK, SVKKL, Medvik, Embase, PubMed, Wiley Online Library, Medscape. The research was conducted from the National Medical Library and from the Central Bohemian Library in Kladno. I got statistical data from web sources, especially from KST. Methodology: The choice of the case study best fulfills the requirements necessary to map the key moments of nursing care, which may play a role in the timely indication of a potential organ donor, as well as in considering...

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The presented diploma thesis deals with the church policy of the Bohemian King John of Bohemia in relation to Upper Lusatia and the Duchy of Wrocław. The areas which thanks to John's successful territorial policy have become an integral part of the Bohemian Kingdom for several centuries. As the named countries belonged to the indivisible dominions of the Bohemian ruler, he was able to fully develop there his donor activities. The research is based on an analysis of available sources especially of a diplomatic nature and is also focused on narrative sources. The aim of this work is to analyse and interpret John's relationship to church institutions especially chapters and monasteries in defined regions. Attention is also paid to the ecclesiastical patronage of Henry of Jawor a longtime competitor of John of Bohemia in the struggle for Upper Lusatia, who ruled over Görlitz until 1329 and over part of Upper Lusatia until the end of his life († 1346). The work would like to contribute to the evaluation of John's support for church institutions, which was aimed at strengthening his position in these areas. Keywords: John of Bohemia; Henry of Jawor; Upper Lusatia; Silesia; Duchy of Wrocław; church policy; donation; confirmation

Tillgängligheten av blod kan vara livsavgörande för många personer, därför är blodgivning en viktig del av vården. För blodgivare kan en regelbunden blodgivning påverka kroppens järndepåer vilket på sikt kan leda till en järnbrist. Syftet med denna studie var att kartlägga blodgivares järndepåer i Region Jönköpings län genom att (i) utvärdera antalet och andelen nyanmälningar som ej uppfyllt godkänd S-ferritinnivå för blodgivning, (ii) jämföra nivåerna av S-ferritin vid nyregistrering och vid upprepad blodgivning, (iii) utvärdera intag av järnprofylax hos blodgivare, (iv) jämföra antalet, andelen samt orsaken till kontrollprovtagningar före och efter S-ferritin infördes som provtagningsrutin. Data insamlades och erhölls från Blodcentralen, Jönköping, Sverige, och analyserades statistiskt. Resultatet visade att fler kvinnor än män ej blev godkända som blodgivare på grund av S-ferritin <22 µg/L. Genom att sänka S-ferritinnivån kan fler kvinnor godkännas för blodgivning. Vidare visade studien att upprepad blodgivning leder till minskade järndepåer. Grupperna som erbjudits järnprofylax hade stabilare S-ferritin över tid vilket antyder att alla blodgivare skulle gynnas av järnprofylax, men vidare studier krävs. Majoriteten av blodgivare med S-ferritin ≤100 µg/L intar erbjudna järntabletter vilket visade att blodgivarna möjliggjorde fortsatt blodgivning. Slutligen visade studien att sedan S-ferritin infördes som provtagningsrutin 2017 har kontrollprovtagningar på grund av lågt B-Hb minskat, vilket visar att risken för att utveckla en järnbrist på grund av upprepad blodgivning har minskat i Region Jönköpings län. / The availability of blood could be crucial for many people; blood donation is, therefore, a vital part of healthcare. Continuous blood donation could affect the blood donors’ iron depots which could lead to an iron deficiency. The aim of the present study was to evaluate and highlight iron depots amongst blood donors in Jönköping County by (i) evaluating the number and proportion of new applicants which did not meet the approved S-ferritin levels for blood donation, (ii) compare the levels of S-ferritin in new registrations and repeated blood donations, (iii) evaluate intake of iron supplements amongst blood donors, (iv) compare the number, proportion and cause for control sampling before and after S-ferritin was introduced as a sampling routine. Data was collected from the Department of Transfusion Medicine, Jönköping, Sweden, and analysed statistically.The result showed that more women than men were not approved for blood donation because of S-ferritin <22 µg/L. By lowering S-ferritin, additional women will be approved for blood donation. Further, the study showed that continuous blood donation leads to decreased iron depots. Groups that were offered iron supplements showed more stable S-ferritin levels over time which implied that all blood donors would benefit from iron supplements, but further studies are required. The majority of the blood donors with S-ferritin ≤100 µg/L were taking their offered iron supplements which showed that the blood donors enabled future blood donations. Lastly, since S-ferritin was introduced as a sampling routine in 2017 the amount of control samplings due to low B-Hb has decreased. This shows that the risk to develop an iron deficiency due to continuous blood donation has decreased in Jönköping County.

Under tidig vår 2021 presenterade den svenska regeringen en proposition som skulle innebära ändringar i transplantationslagen. Eftersom det råder organbrist i Sverige är syftet med propositionen att fler donationer ska möjliggöras. Ett av förslagen är ett borttagande av närståendevetot vilket innebär att anhöriga inte längre har rätt att neka donation från en avliden närstående när donationsviljan är okänd, även kallat ett hard opt out-system. Sverige skulle då bli det tredje landet i världen att införa ett sådant donationssystem. Det finns få studier som undersöker effekten av ett borttagande av närståendevetot, framförallt ur ett samhällsekonomiskt perspektiv. Syftet med vår uppsats är att analysera en sådan systemförändring i Sverige genom en CBA. Som komplement till vår CBA genomför vi en enkätstudie för att analysera vissa icke-monetära effekter. Vi vill också undersöka om inställningen till organdonation har förändrats sedan den senaste undersökningen gjordes år 2015. Resultatet visar en mer positiv inställning till organdonation i vår studie jämfört med tidigare. I huvudkalkylen ger de monetärt värderade effekterna av ett borttagande av närståendevetot en nettobesparing på 427 miljoner kronor. Förutsatt att de icke-monetära effekterna inte uppgår till en kostnad på mer än 427 miljoner kronor är ett borttagande av närståendevetot en samhällsekonomiskt lönsam åtgärd. I känslighetsanalysen presenteras flera alternativa kalkyler där de monetära effekterna ger en positiv nettobesparing i samtliga vilket tyder på ett robust resultat i vår huvudkalkyl. Trots att våra beräkningar tyder på att ett borttagande av närståendevetot leder till en nettobesparing kan uppsatsen inte fastställa om det är den mest kostnadseffektiva åtgärden. Tidigare studier menar att det inte finns bevis för att borttagandet i sig leder till fler donerade organ och att strukturella förändringar kan vara minst lika betydelsefulla, om inte mer. Vi rekommenderar att fler jämförande studier görs med länder som har en hög andel donatorer för att kunna utvärdera vilka åtgärder som skulle vara mest kostnadseffektiva i Sverige. / In early spring 2021, the Swedish government presented a bill that would entail amendments to the Transplantation Act. Since there is an organ shortage in Sweden, the purpose of the bill is to enable more donations. One of the proposals is the removal of the family consent which means that relatives will no longer have the right to refuse donation from a deceased relative when the willingness to donate is unknown, also known as a hard opt out system. This would make Sweden the third country in the world to implement such a donation system. There are few previous studies which examine the economic aspect of removing the family consent. The purpose of our thesis is to analyze such a systemic change in Sweden through a CBA. In addition to our CBA, we conduct a survey to analyze certain non-monetary effects. We also seek to analyze whether the attitude towards organ donation has changed since the most recent survey was conducted in 2015. The results show a more positive attitude towards organ donation in our study compared to earlier research.  In the main calculation, the monetarily valued effects of a removal of the family consent presents net savings of SEK 427 million. Given that the non-monetary effects do not add up to a cost of more than SEK 427 million, a removal of the family consent is a profitable measure from a CBA perspective. The sensitivity analysis presents several alternative calculations where the monetary effects provide a net saving in all of them, which indicates a robust result in our main calculation. Even though our calculations indicate that a removal of the family consent leads to a net saving, we cannot determine if it is the most cost-effective measure. Previous studies suggest that there is no evidence that the removal itself leads to more donated organs and that structural changes can be at least as significant, if not more so. We recommend that additional comparative studies with countries that have a high proportion of donors should be conducted. This would help with the evaluation of which measures would be the most cost-effective in Sweden.

Background: Societies around the world have seen an increased willingness to contribute to social responsibilities activities. One way for corporations to commit to corporate social responsibility (CSR) have been to donate corporate assets. However, donating company assets has been questioned if justifiable. Arguments ranging from the missuses of assets to increased competitive advantage as a part of corporate strategy have been mentioned in connection to corporate donations. These different opinions have created an uncertainty of how corporate donations ultimately will affect a company’s market value. Objective: The objective of this thesis is to distinguish if corporate donations have a significant effect on a company’s market value. It is further examined if different amounts or recipient area of a donation significantly impacts the response to the donation. The aim is to understand if the donation amount is lost or if donating can create value for a company, possibly helping to motivate managers to donate and thus create value for our society. Method: An event-study methodology approach was used to examine abnormal returns associated with corporate donation announcements. Linear regressions were applied to distinguish if different donation amounts or if the recipient area played a significant role regarding how realised donation announcements is interpreted by the market. Result: No market significance regarding abnormal returns was found connected to donation announcements during any of the three studied event windows. The linear regressions performed revealed that the donation amounts significantly affect market reactions during a two day-period before an announcement as well as a seven day-period after the announcement day. Indicating information leakage and lagging reactions to the announcement. Recipient area was identified to not affect abnormal returns with the regressions for any of the investigated event windows. However, through an analysis of means, some specific cases where the donation amount and the recipient area resulted in a significant difference between groups were distinguished. Conclusion: No significant punishment to donating companies was found; hence no lost firm value was identified, indicating that the act of donating is not viewed as inappropriate by the market. Therefore, managers do not need to fear the market’s reactions when planning a corporate donation. Internal value can emerge from the act of donating, in the form of goodwill, brand image, reputation, company image, positioning or awareness. Further, it was determined that neither the donation amount nor the recipient area have a significant relation to the effect for any of the whole event windows tested. / Bakgrund: Samhällen runt om i världen har upplevt en ökad strävan att bidra till samhällsansvar. Ett sätt som företag bidrar till detta är genom att donera sina tillgångar. Dock har användningen av företagstillgångar till detta ändamål ifrågasatts. Där argument som felanvändning av företagstillgångar till konkurrensfördel som en del av företagsstrategi har använts i samband med företagsdonationer. Dessa skilda åsikterna har skapat oklarhet kring hur företagsdonationer verkligen påverkar ett företags marknadsvärde. Syfte: Syftet med denna uppsatts är att urskilja om företagsdonationer har en signifikant effekt på ett företags marknadsvärde. Vidare undersöks om mängden som doneras har betydelse och om mottagarområdet påverkar den initiala reaktionen. Målet är att förstå om donationsvärdet går förlorat eller om donationer kan skapa värde för företag, vilket möjligen kan bidra till att motivera chefer att donera och på så vis skapa värde för samhället. Metod: Event-studiemetoden används för att undersöka abnormal avkastning som förknippas med offentliggörandet av företagsdonationer. Linjära regressioner används för att urskilja om olika donationsmängder eller mottagarområden har ett signifikant inflytande angående hur publikationen av en donation tolkas av marknaden. Resultat: Ingen marknadstäckande signifikans beträffande abnormal avkastning observerades kopplat till offentliggörandet av donationer under något av de tre testade eventfönstren. De linjära regressioner som utfördes avslöjar att donationsmängden signifikant påverkar marknadsreaktioner under en tvådagarsperiod innan offentliggörandet samt under en sjudagarsperiod efter annonseringsdagen. Detta indikerar att det finns informationsläckage och eftersläpande reaktioner kopplat till tillkännagivandet. Mottagarområde påverkade inte abnormal avkastning enligt de utförda regressionerna för något av de testade eventfönsterna. Däremot kunde vissa specifika fall urskiljas genom en medelvärdesanalys där donationsmängd och mottagarområde resulterade i en signifikant skillnad mellan grupperna. Slutsats: Ingen signifikant bestraffning mot donerande företag hittades, därav är inget förlorat företagsvärde identifierat; vilket indikerar att handlingen att donera inte anses som felaktig av investerare. Följaktligen behöver chefer inte bekymra sig för investerares reaktioner i samband med donationer. Inneboende värde kan skapas av akten att donera i form av goodwill, varumärke, rykte, företagssyn, positionering och/eller medvetenhet. Vidare kunde det fastställas att varken donationsmängden eller mottagarområdet har en signifikant relation till effekten under något av de testade eventfönsterna.

Medical researchers are exploring the potential of patients’ mobile phones and wearables for medical studies. The contribution of volunteers in a form of citizen science, where citizens donate their data for research purposes, can enable studies on a large scale. This research area, known as mobile health, often relies on shared data such as tracked steps or self- reporting forms. Privacy, transparency and trust play a fundamental role in the interaction of users with related platforms that agglomerate medical studies.This project explores privacy concerns of potential users of mobile health citizen science apps, summarises similar user patterns and analyses the impact of transparency enhancing tools on the users’ trust. In this context, a prototype with different features that aim to increase the transparency is designed, tested and evaluated. The results indicate how users perceive the importance and the generated trust of the proposed features and provide recommendations for data donation platforms.

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Human infertility is not a new phenomenon, but it is as old as humanity itself. Currently in most developed countries, the number of couples who have a problem with childbearing is growing. This is due, among other things, to the lifestyle associated with career development and postponement of parenthood. While in the past infertile couples usually had only two options to deal with their sterility - childlessness and a substitute life program, or adopting a child. Today, infertile couples have a third option and this is the treatment of infertility using assisted reproduction methods. This year, exactly forty years have elapsed since the birth of the first child by means of extracorporeal fertilization. Already then the assisted reproduction was considered a method that is ethically problematic. Numerous specialists, such as physicians, biologists, lawyers, philosophers, theologians, and others, have been involved in the quest for ethical issues. Not only there has been no solution to some problems during the whole lifetime of assisted reproduction on which most experts and the general public would agree, but with the gradual development of this treatment method new problems have arisen. Today's stage of development of artificial insemination techniques and procedures together with modern...